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3157-27-5,MFCD00816223
Catalog No.:AA00CKIX

3157-27-5 | 3-(1-PHENYL-ETHYL)-3H-IMIDAZOLE-4-CARBOXYLIC ACID

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1mg
2 weeks  
$2,164.00   $1,515.00
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  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00CKIX
Chemical Name:
3-(1-PHENYL-ETHYL)-3H-IMIDAZOLE-4-CARBOXYLIC ACID
CAS Number:
3157-27-5
Molecular Formula:
C12H12N2O2
Molecular Weight:
216.2359
MDL Number:
MFCD00816223
SMILES:
CC(C1=CC=CC=C1)N2C=NC=C2C(=O)O
NSC Number:
168567
Properties
Computed Properties
 
Complexity:
251  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
1  
XLogP3:
2.4  

Literature

Title: Mapping general anesthetic binding site(s) in human α1β3 γ-aminobutyric acid type A receptors with [³H]TDBzl-etomidate, a photoreactive etomidate analogue.

Journal: Biochemistry 20120131

Title: GABA(A) receptors as molecular targets of general anesthetics: identification of binding sites provides clues to allosteric modulation.

Journal: Canadian journal of anaesthesia = Journal canadien d'anesthesie 20110101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: New insights into the molecular mechanisms of general anaesthetics.

Journal: British journal of pharmacology 20100901

Title: Identification of binding sites in the nicotinic acetylcholine receptor for TDBzl-etomidate, a photoreactive positive allosteric effector.

Journal: The Journal of biological chemistry 20080808

Title: Synthesis of trifluoromethylaryl diazirine and benzophenone derivatives of etomidate that are potent general anesthetics and effective photolabels for probing sites on ligand-gated ion channels.

Journal: Journal of medicinal chemistry 20060810

Title: [18F]FETO: metabolic considerations.

Journal: European journal of nuclear medicine and molecular imaging 20060801

Title: [18F]FETO for adrenocortical PET imaging: a pilot study in healthy volunteers.

Journal: European journal of nuclear medicine and molecular imaging 20060601

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: In vivo and in vitro evaluation of [18F]FETO with respect to the adrenocortical and GABAergic system in rats.

Journal: European journal of nuclear medicine and molecular imaging 20031001

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