Home Other Building Blocks 3200-06-4
3200-06-4,MFCD00079473
Catalog No.:AA00I5ZL

3200-06-4 | Nafronyl oxalate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
99%
in stock  
$75.00   $53.00
- +
1g
99%
in stock  
$93.00   $65.00
- +
5g
99%
in stock  
$195.00   $137.00
- +
25g
99%
in stock  
$670.00   $469.00
- +
100g
99%
in stock  
$2,257.00   $1,580.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00I5ZL
Chemical Name:
Nafronyl oxalate
CAS Number:
3200-06-4
Molecular Formula:
C26H35NO7
Molecular Weight:
473.5586
MDL Number:
MFCD00079473
SMILES:
OC(=O)C(=O)O.CCN(CCOC(=O)C(Cc1cccc2c1cccc2)CC1CCCO1)CC
Properties
Computed Properties
 
Complexity:
536  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
12  
Undefined Atom Stereocenter Count:
2  

Downstream Synthesis Route

[1]BioorganicandMedicinalChemistryLetters,2012,vol.22,p.3441-3444

[1]BioorganicandMedicinalChemistryLetters,2012,vol.22,p.3441-3444

[1]Kiwala,Dawid;Olbrycht,Maksymilian;Balawejder,Maciej;Piatkowski,Wojciech;Seidel-Morgenstern,Andreas;Antos,Dorota[OrganicProcessResearchandDevelopment,2016,vol.20,#3,p.615-625]

Literature

Title: Intravenous naftidrofuryl for critical limb ischaemia.

Journal: The Cochrane database of systematic reviews 20120711

Title: Practical access to four stereoisomers of naftidrofuryl and their binding affinity towards 5-hydroxytryptamine 2A receptor.

Journal: Bioorganic & medicinal chemistry letters 20120515

Title: Naftidrofuryl for dementia.

Journal: The Cochrane database of systematic reviews 20111207

Title: A systematic review and economic evaluation of cilostazol, naftidrofuryl oxalate, pentoxifylline and inositol nicotinate for the treatment of intermittent claudication in people with peripheral arterial disease.

Journal: Health technology assessment (Winchester, England) 20111201

Title: A discovery of novel Mycobacterium tuberculosis pantothenate synthetase inhibitors based on the molecular mechanism of actinomycin D inhibition.

Journal: Bioorganic & medicinal chemistry letters 20110701

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: I suffer from frequent leg cramps and I've heard that quinine can help. Should I consider taking it?

Journal: The Johns Hopkins medical letter health after 50 20100601

Title: Silence of the limbs pharmacological symptomatic treatment of intermittent claudication.

Journal: Current vascular pharmacology 20100501

Title: Assessment: symptomatic treatment for muscle cramps (an evidence-based review): report of the therapeutics and technology assessment subcommittee of the American academy of neurology.

Journal: Neurology 20100223

Title: Vasodilators and vasoactive substances for idiopathic sudden sensorineural hearing loss.

Journal: The Cochrane database of systematic reviews 20091007

Title: Fatal intoxication with naftidrofuryl.

Journal: Legal medicine (Tokyo, Japan) 20090901

Title: Assessment of binding affinity to 5-hydroxytryptamine 2A (5-HT2A) receptor and inverse agonist activity of naftidrofuryl: comparison with those of sarpogrelate.

Journal: Journal of pharmacological sciences 20090801

Title: Pharmacologic therapy for intermittent claudication.

Journal: Pharmacotherapy 20090501

Title: Naftidrofuryl for intermittent claudication: meta-analysis based on individual patient data.

Journal: BMJ (Clinical research ed.) 20090101

Title: Naftidrofuryl for intermittent claudication.

Journal: The Cochrane database of systematic reviews 20080416

Title: [Idiopathic sudden sensorineural hearing loss. What's the appropriate management?].

Journal: La Tunisie medicale 20071001

Title: Naftidrofuryl for acute stroke.

Journal: The Cochrane database of systematic reviews 20070418

Title: A novel inhibitor of Mycobacterium tuberculosis pantothenate synthetase.

Journal: Journal of biomolecular screening 20070201

Title: Prognostic indicators of management of sudden sensorineural hearing loss in an Asian hospital.

Journal: Singapore medical journal 20070101

Title: [Inpatient infusion treatment for acute tinnitus with and without adjuvant psychotherapeutic intervention. A comparison of psychological effectiveness].

Journal: HNO 20061001

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Cost effectiveness of cilostazol compared with naftidrofuryl and pentoxifylline in the treatment of intermittent claudication in the UK.

Journal: Current medical research and opinion 20050601

Title: Acral necrosis after inadequate excessive administration of bleomycin in a testicular cancer patient.

Journal: Onkologie 20050101

Title: Pharmacokinetics of naftidrofuryl in patients with renal impairment.

Journal: Arzneimittel-Forschung 20050101

Title: Naftidrofuryl: a review of its use in the treatment of intermittent claudication.

Journal: Drugs & aging 20050101

Title: Calcium oxalate deposition in renal allografts: morphologic spectrum and clinical implications.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040801

Title: [Secondary prevention and conservative therapy of obliterative arteriosclerosis].

Journal: Orvosi hetilap 20040516

Title: [Evidence-based therapy of intermittent claudication].

Journal: Krankenpflege Journal 20040101

Title: Naftidrofuryl-induced liver injury.

Journal: The American journal of gastroenterology 20030601

Title: Raynaud's phenomenon (primary).

Journal: Clinical evidence 20030601

Title: Naftidrofuryl-driven regulation of endothelial ICAM-1 involves nitric oxide.

Journal: Free radical biology & medicine 20030301

Title: Characterization of the CNS effects of naftidrofuryl (Praxilène) by quantitative EEG and functional MRI: a study in healthy elderly subjects.

Journal: Neuropsychobiology 20030101

Title: Can claudication be improved with medication?

Journal: Seminars in vascular surgery 20021201

Title: Nocturnal leg cramps in older people.

Journal: Postgraduate medical journal 20021001

Title: Reduction of endothelin-1 binding and inhibition of endothelin-1-mediated detrusor contraction by naftidrofuryl.

Journal: Clinical science (London, England : 1979) 20020801

Title: Vitamin A metabolism is altered in brown Norway and long-Evans rats infused with naftidrofuryl or erythromycin intravenously.

Journal: International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20020701

Title: Findings of the Naftidrofuryl in Quality of Life (NIQOL) European study program.

Journal: International angiology : a journal of the International Union of Angiology 20020301

Title: Naftidrofuryl exerts antiserotonergic but no endothelin-receptor blocking effects in AS4.1 cells, juxtaglomerular cells and isolated perfused rat kidneys.

Journal: Journal of cardiovascular pharmacology 20020101

Title: Effect of naftidrofuryl on intramuscular partial oxygen pressure (pO2) prior to, during and after physical load on the treadmill in apparently healthy subjects.

Journal: Clinical hemorheology and microcirculation 20020101

Title: [Current EMNID survey on peripheral arterial occlusive disease].

Journal: Krankenpflege Journal 20020101

Title: [Application of prostaglandin E1 and Naftidrofuryl in combined treatment of purulent-necrotic complications of the diabetic foot syndrome].

Journal: Klinichna khirurhiia 20020101

Title: Naftidrofuryl in quality of life (NIQOL). A Belgian study.

Journal: International angiology : a journal of the International Union of Angiology 20011201

Title: Naftidrofuryl in the treatment of vascular dementia.

Journal: European archives of psychiatry and clinical neuroscience 20011201

Title: Pharmacotherapy of intermittent claudication.

Journal: Expert opinion on pharmacotherapy 20011101

Title: [Intermittent claudication. Walking plus vasoactive drug treatment].

Journal: MMW Fortschritte der Medizin 20010705

Title: [Deleterious cardiac effects of serotonin in myocardial ischemia: role of naftidrofuryl].

Journal: Annales de cardiologie et d'angeiologie 20010601

Title: Treatment alternatives for nocturnal leg cramps.

Journal: The Medical journal of Australia 20010521

Title: New treatment options in intermittent claudication: the US experience.

Journal: International journal of clinical practice. Supplement 20010401

Title: [Effect of naftidrofuryl on physiological walking distance in patients with intermittent claudication].

Journal: Annales de cardiologie et d'angeiologie 20010401

Title: A new study demonstrates the efficacy of naftidrofuryl in the treatment of intermittent claudication. Findings of the Naftidrofuryl Clinical Ischemia Study (NCIS).

Journal: International angiology : a journal of the International Union of Angiology 20010301

Title: Behavioral studies of the effects of moderate oligemic hypoxia caused by bilateral clamping of carotid arteries in mice. Impairment of spatial working memory.

Journal: Polish journal of pharmacology 19980101

Title: Naftidrofuryl oxalate, nootropic effects on the scopolamine- and the basal forebrain lesion-induced amnesia in rats.

Journal: Pharmacology, biochemistry, and behavior 19910801

Title: Naftidrofuryl

Title: Meng Y, et al. Cost-effectiveness of cilostazol, naftidrofuryl oxalate, and pentoxifylline for the treatment of intermittent claudication in people with peripheral arterial disease. Angiology. 2014 Mar;65(3):190-197.

Title: Stevens JW, et al. Systematic review of the efficacy of cilostazol, naftidrofuryl oxalate and pentoxifylline for the treatment of intermittent claudication. Br J Surg. 2012 Dec;99(12):1630-1638.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 3200-06-4
Tags:3200-06-4 Molecular Formula|3200-06-4 MDL|3200-06-4 SMILES|3200-06-4 Nafronyl oxalate