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321-14-2,MFCD00002457
Catalog No.:AA0037AN

321-14-2 | 5-Chlorosalicylic acid

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25g
98%
in stock  
$13.00   $9.00
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100g
98%
in stock  
$19.00   $14.00
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500g
98%
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$44.00   $31.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0037AN
Chemical Name:
5-Chlorosalicylic acid
CAS Number:
321-14-2
Molecular Formula:
C7H5ClO3
Molecular Weight:
172.5658
MDL Number:
MFCD00002457
SMILES:
Clc1ccc(c(c1)C(=O)O)O
NSC Number:
30111
Properties
Properties
 
BP:
320.5°C at 760 mmHg  
Form:
Solid  
MP:
171-176 °C  
Refractive Index:
1.4580 (estimate)  
Solubility:
1g/l  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
160  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
3.1  

Literature

Title: Effect of biological confinement on the photophysics and dynamics of a proton-transfer phototautomer: an exploration of excitation and emission wavelength-dependent photophysics of the protein-bound drug.

Journal: Physical chemistry chemical physics : PCCP 20120921

Title: Antimicrobial activity of sulfonamides containing 5-chloro-2-hydroxybenzaldehyde and 5-chloro-2-hydroxybenzoic acid scaffold.

Journal: European journal of medicinal chemistry 20120401

Title: Two centrosymmetric dinuclear phenanthroline-copper(II) complexes with 3,5-dichloro-2-hydroxybenzoic acid and 5-chloro-2-hydroxybenzoic acid.

Journal: Acta crystallographica. Section C, Crystal structure communications 20120401

Title: Structure-activity relationship of salicylic acid derivatives on inhibition of TNF-α dependent NFκB activity: Implication on anti-inflammatory effect of N-(5-chlorosalicyloyl)phenethylamine against experimental colitis.

Journal: European journal of medicinal chemistry 20120201

Title: Fluorescence-based high-throughput screening assay for drug interactions with UGT1A6.

Journal: Assay and drug development technologies 20111001

Title: Structural, vibrational and quantum chemical investigations on 5-chloro-2-hydroxybenzamide and 5-chloro-2-hydroxybenzoic acid.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110901

Title: SA-ABA antagonism in defense responses.

Journal: Plant signaling & behavior 20101001

Title: catena-Poly[[(1,10-phenanthroline)lead(II)]bis-(μ-5-chloro-2-hy-droxy-benzoato)].

Journal: Acta crystallographica. Section E, Structure reports online 20100801

Title: Bismuth(III) complexes derived from non-steroidal anti-inflammatory drugs and their activity against Helicobacter pylori.

Journal: Dalton transactions (Cambridge, England : 2003) 20100321

Title: Deciphering the photophysics of 5-chlorosalicylic acid: evidence for excited-state intramolecular proton transfer.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20100101

Title: Novel metal-binding site of Pseudomonas reinekei MT1 trans-dienelactone hydrolase.

Journal: Biochemical and biophysical research communications 20091225

Title: trans-Dienelactone hydrolase from Pseudomonas reinekei MT1, a novel zinc-dependent hydrolase.

Journal: Biochemical and biophysical research communications 20081114

Title: In vitro inhibition of salicylic acid derivatives on human cytosolic carbonic anhydrase isozymes I and II.

Journal: Bioorganic & medicinal chemistry 20081015

Title: Transport evaluation of salicylic acid and structurally related compounds across Caco-2 cell monolayers and artificial PAMPA membranes.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20081001

Title: Bis(5-chloro-salicylato-κO)bis-(1,10-phenanthroline-κN,N')cadmium(II).

Journal: Acta crystallographica. Section E, Structure reports online 20080701

Title: Salicylate activity. 1. Protection of plants from paraquat injury.

Journal: Journal of agricultural and food chemistry 20051214

Title: Salicylate activity. 3. Structure relationship to systemic acquired resistance.

Journal: Journal of agricultural and food chemistry 20051214

Title: Guest-controlling effects on ER behaviors of beta-cyclodextrin polymer.

Journal: Journal of colloid and interface science 20050901

Title: Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach.

Journal: Journal of medicinal chemistry 20050407

Title: Anaerobic degradation and dehalogenation of chlorosalicylates and salicylate under four reducing conditions.

Journal: Biodegradation 20010101

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