3307-39-9,MFCD00002647
Catalog No.:AA0029A2

3307-39-9 | 2-(4-Chlorophenoxy) propionic acid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
99%(HPLC)
in stock  
$43.00   $30.00
- +
1g
98%
in stock  
$91.00   $64.00
- +
5g
98%
in stock  
$250.00   $175.00
- +
10g
98%
in stock  
$408.00   $286.00
- +
25g
98%
in stock  
$726.00 $508.00
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA0029A2
Chemical Name:
2-(4-Chlorophenoxy) propionic acid
CAS Number:
3307-39-9
Molecular Formula:
C9H9ClO3
Molecular Weight:
200.6190
MDL Number:
MFCD00002647
SMILES:
CC(C(=O)O)Oc1ccc(cc1)Cl
NSC Number:
70174
Properties
Computed Properties
 
Complexity:
176  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0  
XLogP3:
2.3  

Downstream Synthesis Route

[1]Haskelberg[JournalofOrganicChemistry,1947,vol.12,p.435][JournalofOrganicChemistry,1948,vol.13,p.937]

3307-39-9    538-09-0   
2-(4-Chloro-phenoxy)-propionicacid(1R,3R,5S)-(8-aza-bicyclo3.2.1oct-3-yl)ester 

[1]JournalofMedicinalChemistry,1994,vol.37,p.1712-1719

[1]Arzneimittel-Forschung/DrugResearch,1975,vol.25,p.1686-1692

116-02-9    3307-39-9   
(S)-2-(4-Chloro-phenoxy)-propionicacid3,3,5-trimethyl-cyclohexylester 

[1]Arzneimittel-Forschung/DrugResearch,1975,vol.25,p.1686-1692

[1]Arzneimittel-Forschung/DrugResearch,1975,vol.25,p.1686-1692

Literature

Title: Toxicokinetics, including saturable protein binding, of 4-chloro-2-methyl phenoxyacetic acid (MCPA) in patients with acute poisoning.

Journal: Toxicology letters 20110325

Title: Purification and gene cloning of an enantioselective thioesterification enzyme from Brevibacterium ketoglutamicum KU1073, a deracemization bacterium of 2-(4-chlorophenoxy)propanoic acid.

Journal: Bioscience, biotechnology, and biochemistry 20100101

Title: Physiology and pathophysiology of ClC-K/barttin channels.

Journal: Frontiers in physiology 20100101

Title: Molecular Pharmacology of Kidney and Inner Ear CLC-K Chloride Channels.

Journal: Frontiers in pharmacology 20100101

Title: Combined use of biomarkers and in situ bioassays in Daphnia magna to monitor environmental hazards of pesticides in the field.

Journal: Environmental toxicology and chemistry 20070201

Title: Radiolytic degradation of herbicide 4-chloro-2-methyl phenoxyacetic acid (MCPA) by gamma-radiation for environmental protection.

Journal: Ecotoxicology and environmental safety 20061001

Title: Differential effects of pyrazinamide and clofibrate on gene expression of rat hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme of the tryptophan-NAD pathway.

Journal: International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20060501

Title: Channel or transporter? The CLC saga continues.

Journal: Experimental physiology 20060101

Title: Activation and inhibition of kidney CLC-K chloride channels by fenamates.

Journal: Molecular pharmacology 20060101

Title: Diversity of Cl(-) channels.

Journal: Cellular and molecular life sciences : CMLS 20060101

Title: Phenoxyacetic acid herbicide exposure for women on Ontario farms.

Journal: Journal of toxicology and environmental health. Part A 20050813

Title: Molecular determinants of differential pore blocking of kidney CLC-K chloride channels.

Journal: EMBO reports 20040601

Title: CLC-K channels: if the drug fits, use it.

Journal: EMBO reports 20040601

Title: Investigations of pharmacologic properties of the renal CLC-K1 chloride channel co-expressed with barttin by the use of 2-(p-Chlorophenoxy)propionic acid derivatives and other structurally unrelated chloride channels blockers.

Journal: Journal of the American Society of Nephrology : JASN 20040101

Title: Structural requisites of 2-(p-chlorophenoxy)propionic acid analogues for activity on native rat skeletal muscle chloride conductance and on heterologously expressed CLC-1.

Journal: British journal of pharmacology 20030801

Title: Molecular requisites for drug binding to muscle CLC-1 and renal CLC-K channel revealed by the use of phenoxy-alkyl derivatives of 2-(p-chlorophenoxy)propionic acid.

Journal: Molecular pharmacology 20020801

Title: Exposure to pesticides as risk factor for non-Hodgkin's lymphoma and hairy cell leukemia: pooled analysis of two Swedish case-control studies.

Journal: Leukemia & lymphoma 20020501

Title: Fast and slow gating of CLC-1: differential effects of 2-(4-chlorophenoxy) propionic acid and dominant negative mutations.

Journal: Molecular pharmacology 20010701

Title: [Pharmacological analysis of the antihypoxic action of aminobutyric acid derivatives].

Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20010101

Title: Pharmacological characterization of chloride channels belonging to the ClC family by the use of chiral clofibric acid derivatives.

Journal: Molecular pharmacology 20000901

Title: Modulation of the gating of CIC-1 by S-(-) 2-(4-chlorophenoxy) propionic acid.

Journal: British journal of pharmacology 19990301

Quotation Request
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Additional Info:
SDS
Historical Records
Tags:3307-39-9 Molecular Formula|3307-39-9 MDL|3307-39-9 SMILES|3307-39-9 2-(4-Chlorophenoxy) propionic acid
Catalog No.: AA0029A2
3307-39-9,MFCD00002647
3307-39-9 | 2-(4-Chlorophenoxy) propionic acid
Pack Size: 100mg
Purity: 99%(HPLC)
in stock
$43.00 $30.00
Pack Size: 1g
Purity: 98%
in stock
$91.00 $64.00
Pack Size: 5g
Purity: 98%
in stock
$250.00 $175.00
Pack Size: 10g
Purity: 98%
in stock
$408.00 $286.00
Pack Size: 25g
Purity: 98%
in stock
$726.00 $508.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA0029A2
Chemical Name: 2-(4-Chlorophenoxy) propionic acid
CAS Number: 3307-39-9
Molecular Formula: C9H9ClO3
Molecular Weight: 200.6190
MDL Number: MFCD00002647
SMILES: CC(C(=O)O)Oc1ccc(cc1)Cl
NSC Number: 70174
Properties
Complexity: 176  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 13  
Hydrogen Bond Acceptor Count: 3  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 3  
Undefined Atom Stereocenter Count: 1  
Undefined Bond Stereocenter Count: 0  
XLogP3: 2.3  
Downstream Synthesis Route
940-31-8    3307-39-9 

[1]Haskelberg[JournalofOrganicChemistry,1947,vol.12,p.435][JournalofOrganicChemistry,1948,vol.13,p.937]

3307-39-9    538-09-0   
2-(4-Chloro-phenoxy)-propionicacid(1R,3R,5S)-(8-aza-bicyclo3.2.1oct-3-yl)ester 

[1]JournalofMedicinalChemistry,1994,vol.37,p.1712-1719

3307-39-9    116-02-9    58327-11-0 

[1]Arzneimittel-Forschung/DrugResearch,1975,vol.25,p.1686-1692

116-02-9    3307-39-9   
(S)-2-(4-Chloro-phenoxy)-propionicacid3,3,5-trimethyl-cyclohexylester 

[1]Arzneimittel-Forschung/DrugResearch,1975,vol.25,p.1686-1692

3307-39-9    59-46-1    27474-47-1 

[1]Arzneimittel-Forschung/DrugResearch,1975,vol.25,p.1686-1692

Literature fold

Title: Toxicokinetics, including saturable protein binding, of 4-chloro-2-methyl phenoxyacetic acid (MCPA) in patients with acute poisoning.

Journal: Toxicology letters20110325

Title: Purification and gene cloning of an enantioselective thioesterification enzyme from Brevibacterium ketoglutamicum KU1073, a deracemization bacterium of 2-(4-chlorophenoxy)propanoic acid.

Journal: Bioscience, biotechnology, and biochemistry20100101

Title: Physiology and pathophysiology of ClC-K/barttin channels.

Journal: Frontiers in physiology20100101

Title: Molecular Pharmacology of Kidney and Inner Ear CLC-K Chloride Channels.

Journal: Frontiers in pharmacology20100101

Title: Combined use of biomarkers and in situ bioassays in Daphnia magna to monitor environmental hazards of pesticides in the field.

Journal: Environmental toxicology and chemistry20070201

Title: Radiolytic degradation of herbicide 4-chloro-2-methyl phenoxyacetic acid (MCPA) by gamma-radiation for environmental protection.

Journal: Ecotoxicology and environmental safety20061001

Title: Differential effects of pyrazinamide and clofibrate on gene expression of rat hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme of the tryptophan-NAD pathway.

Journal: International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition20060501

Title: Channel or transporter? The CLC saga continues.

Journal: Experimental physiology20060101

Title: Activation and inhibition of kidney CLC-K chloride channels by fenamates.

Journal: Molecular pharmacology20060101

Title: Diversity of Cl(-) channels.

Journal: Cellular and molecular life sciences : CMLS20060101

Title: Phenoxyacetic acid herbicide exposure for women on Ontario farms.

Journal: Journal of toxicology and environmental health. Part A20050813

Title: Molecular determinants of differential pore blocking of kidney CLC-K chloride channels.

Journal: EMBO reports20040601

Title: CLC-K channels: if the drug fits, use it.

Journal: EMBO reports20040601

Title: Investigations of pharmacologic properties of the renal CLC-K1 chloride channel co-expressed with barttin by the use of 2-(p-Chlorophenoxy)propionic acid derivatives and other structurally unrelated chloride channels blockers.

Journal: Journal of the American Society of Nephrology : JASN20040101

Title: Structural requisites of 2-(p-chlorophenoxy)propionic acid analogues for activity on native rat skeletal muscle chloride conductance and on heterologously expressed CLC-1.

Journal: British journal of pharmacology20030801

Title: Molecular requisites for drug binding to muscle CLC-1 and renal CLC-K channel revealed by the use of phenoxy-alkyl derivatives of 2-(p-chlorophenoxy)propionic acid.

Journal: Molecular pharmacology20020801

Title: Exposure to pesticides as risk factor for non-Hodgkin's lymphoma and hairy cell leukemia: pooled analysis of two Swedish case-control studies.

Journal: Leukemia & lymphoma20020501

Title: Fast and slow gating of CLC-1: differential effects of 2-(4-chlorophenoxy) propionic acid and dominant negative mutations.

Journal: Molecular pharmacology20010701

Title: [Pharmacological analysis of the antihypoxic action of aminobutyric acid derivatives].

Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994)20010101

Title: Pharmacological characterization of chloride channels belonging to the ClC family by the use of chiral clofibric acid derivatives.

Journal: Molecular pharmacology20000901

Title: Modulation of the gating of CIC-1 by S-(-) 2-(4-chlorophenoxy) propionic acid.

Journal: British journal of pharmacology19990301

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