Home Amines 34183-22-7
34183-22-7,MFCD00079243
Catalog No.:AA0038YN

34183-22-7 | 1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
99%
in stock  
$19.00   $14.00
- +
5g
99%
in stock  
$60.00   $42.00
- +
25g
98%
in stock  
$170.00   $119.00
- +
100g
98%
in stock  
$411.00   $288.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0038YN
Chemical Name:
1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one hydrochloride
CAS Number:
34183-22-7
Molecular Formula:
C21H28ClNO3
Molecular Weight:
377.9049
MDL Number:
MFCD00079243
SMILES:
CCCNCC(COc1ccccc1C(=O)CCc1ccccc1)O.Cl
NSC Number:
758640
Properties
Computed Properties
 
Complexity:
368  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
11  
Undefined Atom Stereocenter Count:
1  

Downstream Synthesis Route
34183-22-7    1245615-27-3   
CASUnavailable 

[1]Neidlein;Wu;Hege[Arzneimittel-Forschung/DrugResearch,1988,vol.38,#9,p.1257-1262]

[2]Neidlein;Wu;Hege[Arzneimittel-Forschung/DrugResearch,1988,vol.38,#9,p.1257-1262]

CASUnavailable 
  34183-22-7    907997-07-3 

[1]Getova;Bontchev;Mehandjiev;Bontchev[Polyhedron,2006,vol.25,#11,p.2254-2260]

CASUnavailable 
  34183-22-7    907997-08-4 

[1]Getova;Bontchev;Mehandjiev;Bontchev[Polyhedron,2006,vol.25,#11,p.2254-2260]

[1]Zhao,Da;Xu,Peng;Ritter,Tobias[Chem,2019,vol.5,#1,p.97-107]

[2]Jiao,Ning;Liu,Jianzhong;Qiu,Xu;Song,Song;Wei,Jialiang;Wen,Xiaojin;Zhang,Cheng;Zhang,Ziyao[Science,2020,vol.367,#6475,p.281-285]

Literature

Title: Humanizing the zebrafish liver shifts drug metabolic profiles and improves pharmacokinetics of CYP3A4 substrates.

Journal: Archives of toxicology 20170301

Title: DDPH, a novel antihypertensive agent, is a potential dual inhibitor of hepatic CYP2D and CYP3A.

Journal: Chemico-biological interactions 20160305

Title: Structural basis of drugs that increase cardiac inward rectifier Kir2.1 currents.

Journal: Cardiovascular research 20141101

Title: Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20131201

Title: Pharmacologic cardiac resynchronization of a 1-year-old boy with severe left ventricular dysfunction.

Journal: Pediatric cardiology 20121001

Title: Palmitate increases the susceptibility of cells to drug-induced toxicity: an in vitro method to identify drugs with potential contraindications in patients with metabolic disease.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20121001

Title: Lead optimization of antimalarial propafenone analogues.

Journal: Journal of medicinal chemistry 20120712

Title: The novel phenylpropiophenone derivates induced relaxation of isolated rat aorta.

Journal: Arzneimittel-Forschung 20120701

Title: Cardioprotective effect of glucose-insulin on acute propafenone toxicity in rat.

Journal: The American journal of emergency medicine 20120601

Title: Variegate porphyria and atrial fibrillation: acute attack induced by propafenone.

Journal: Revista espanola de cardiologia (English ed.) 20120501

Title: Use of rate control medication before cardioversion of recent-onset atrial fibrillation or flutter in the emergency department is associated with reduced success rates.

Journal: CJEM 20120501

Title: Structure-activity relationships, ligand efficiency, and lipophilic efficiency profiles of benzophenone-type inhibitors of the multidrug transporter P-glycoprotein.

Journal: Journal of medicinal chemistry 20120412

Title: Systematic review and meta-analysis of the efficacy of cardioversion by vernakalant and comparators in patients with atrial fibrillation.

Journal: Cardiovascular drugs and therapy 20120401

Title: Cardioversion of acute atrial fibrillation in the emergency department: a prospective randomised trial.

Journal: Emergency medicine journal : EMJ 20120301

Title: A liquid chromatography-electrospray tandem mass spectrometry method for the determination of antiarrhythmic drugs and their metabolites in forensic whole blood samples.

Journal: Journal of analytical toxicology 20120301

Title: Atrial fibrillation and the pharmacological treatment: the role of propafenone.

Journal: European review for medical and pharmacological sciences 20120201

Title: Atrial-selective sodium channel block strategy to suppress atrial fibrillation: ranolazine versus propafenone.

Journal: The Journal of pharmacology and experimental therapeutics 20120101

Title: Benign symptomatic premature ventricular complexes: short- and long-term efficacy of antiarrhythmic drugs and radiofrequency ablation.

Journal: Kardiologia polska 20120101

Title: [Not so simple procedure in 'simple' arrhythmias of ventricular].

Journal: Kardiologia polska 20120101

Title: [Termination of paroxysm of atrial fibrillation conversion using oral propafenone after unsuccessful electrical cardioversion].

Journal: Kardiologiia 20120101

Title: [Propafenone in the treatment of cardiac arrhythmias].

Journal: Kardiologiia 20120101

Title: Second case of the use of intravenous fat emulsion therapy for propafenone toxicity.

Journal: Clinical toxicology (Philadelphia, Pa.) 20111201

Title: Optimization of propafenone analogues as antimalarial leads.

Journal: Journal of medicinal chemistry 20111110

Title: Efficacy and potency of class I antiarrhythmic drugs for suppression of Ca2+ waves in permeabilized myocytes lacking calsequestrin.

Journal: Journal of molecular and cellular cardiology 20111101

Title: Pharmacological conversion of recent atrial fibrillation: a randomized, placebo-controlled study of three antiarrhythmic drugs.

Journal: Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20111101

Title: Syncope following 'pill-in-the-pocket' treatment of atrial fibrillation with propafenone plus quinidine.

Journal: Heart (British Cardiac Society) 20111001

Title: A rare cause of atrial fibrillation: a European hornet sting.

Journal: Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20110901

Title: Overdose of propafenone surreptitiously sold as 'Percocet'.

Journal: The Journal of emergency medicine 20110801

Title: Intravenous fat emulsion therapy for intentional propafenone intoxication.

Journal: Clinical toxicology (Philadelphia, Pa.) 20110801

Title: [Evaluation of shensongyangxin capsules in the treatment of paroxysmal atrial fibrillation: a randomized, double-blind and controlled multicenter trial].

Journal: Zhonghua yi xue za zhi 20110628

Title: Comparative pharmacokinetics between a microdose and therapeutic dose for clarithromycin, sumatriptan, propafenone, paracetamol (acetaminophen), and phenobarbital in human volunteers.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20110614

Title: Selective regulation of cardiac organic cation transporter novel type 2 (OCTN2) in dilated cardiomyopathy.

Journal: The American journal of pathology 20110601

Title: Likelihood of Brugada ECG pattern confirmed after propafenone administration for atrial fibrillation cardioversion.

Journal: Acta cardiologica 20110601

Title: Exhaustive sampling of docking poses reveals binding hypotheses for propafenone type inhibitors of P-glycoprotein.

Journal: PLoS computational biology 20110501

Title: Trapping and dissociation of propafenone derivatives in HERG channels.

Journal: British journal of pharmacology 20110401

Title: Inhibition of cardiac Ca2+ release channels (RyR2) determines efficacy of class I antiarrhythmic drugs in catecholaminergic polymorphic ventricular tachycardia.

Journal: Circulation. Arrhythmia and electrophysiology 20110401

Title: Effects of diltiazem and propafenone on the inactivation and recovery kinetics of fKv1.4 channel currents expressed in Xenopus oocytes.

Journal: Acta pharmacologica Sinica 20110401

Title: Mixed treatment comparison of dronedarone, amiodarone, sotalol, flecainide, and propafenone, for the management of atrial fibrillation.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110301

Title: Mixed treatment comparisons for atrial fibrillation: evidence network or bewildering entanglement?

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110301

Title: [Concealed Brugada syndrome that became apparent incidentally during atrial fibrillation therapy].

Journal: Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir 20110301

Title: Propafenone contraindicated in the elderly?

Journal: Heart (British Cardiac Society) 20110201

Title: Canadian Cardiovascular Society atrial fibrillation guidelines 2010: rate and rhythm management.

Journal: The Canadian journal of cardiology 20110101

Title: Atrial fibrillation (acute onset).

Journal: BMJ clinical evidence 20110101

Title: [Good laboratory practice of equilibrium solubility measurement II. Study of pH-dependent solubility of ionizable compounds].

Journal: Acta pharmaceutica Hungarica 20110101

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: A real-time screening assay for GIRK1/4 channel blockers.

Journal: Journal of biomolecular screening 20101201

Title: Identification of human Ether-à-go-go related gene modulators by three screening platforms in an academic drug-discovery setting.

Journal: Assay and drug development technologies 20101201

Title: Profuse oral secretions after propafenone administration in neonates.

Journal: The Journal of pediatrics 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Images in emergency medicine. Reversible QRS complex widening after oral administration of propafenone.

Journal: Emergency medicine journal : EMJ 20101101

Title: Successful treatment of suicidal mega dose of propafenone intoxication - a case report.

Journal: Kardiologia polska 20101101

Title: [Editorial].

Journal: Kardiologia polska 20101101

Title: Overlapping binding sites of structurally different antiarrhythmics flecainide and propafenone in the subunit interface of potassium channel Kv2.1.

Journal: The Journal of biological chemistry 20101029

Title: 'Pill-in-the-pocket' treatment for recent-onset atrial fibrillation.

Journal: Heart (British Cardiac Society) 20101001

Title: Management of patients with acute atrial fibrillation in the ED.

Journal: The American journal of emergency medicine 20101001

Title: [When and how to treat ventricular ectopic beats].

Journal: Giornale italiano di cardiologia (2006) 20101001

Title: Mechanisms of melanogenesis inhibition by propafenone.

Journal: Archives of dermatological research 20100901

Title: Unstable wide complex tachycardia during propafenone therapy.

Journal: Resuscitation 20100801

Title: Efficacy of propafenone hydrochloride in preventing postoperative atrial fibrillation after coronary artery bypass grafting.

Journal: The heart surgery forum 20100801

Title: Stereoselective glucuronidation of propafenone and its analogues by human recombinant UGT1A9.

Journal: Chemical & pharmaceutical bulletin 20100601

Title: [The efficacy of propafenon in the case of supraventricular atrioventricular tachycardia].

Journal: Georgian medical news 20100601

Title: Atrial fibrillation: adverse effects of 'pill-in-the-pocket' treatment and propafenone-carvedilol interaction.

Journal: International journal of cardiology 20100415

Title: Intravenous administration of flecainide or propafenone in patients with recent-onset atrial fibrillation does not predict adverse effects during 'pill-in-the-pocket' treatment.

Journal: Heart (British Cardiac Society) 20100401

Title: [Ventricular preexcitation: is risk stratification feasible?].

Journal: Giornale italiano di cardiologia (2006) 20100401

Title: High-resolution esophageal manometry with ECG monitoring for management of premature ventricular complexes-associated dysphagia.

Journal: Dysphagia 20100301

Title: The hERG potassium channel and drug trapping: insight from docking studies with propafenone derivatives.

Journal: ChemMedChem 20100301

Title: Physician stated atrial fibrillation management in light of treatment guidelines: data from an international, observational prospective survey.

Journal: Clinical cardiology 20100301

Title: Propafenone poisoning--a case report with plasma propafenone concentrations.

Journal: Journal of medical toxicology : official journal of the American College of Medical Toxicology 20100301

Title: Electrophysiological effects, efficacy and safety of intravenous propafenone in termination of atrioventricular nodal reentrant tachycardia and atrioventricular reentrant tachycardia: a prospective non-randomized interventional study.

Journal: Acta clinica Croatica 20100301

Title: [Instead of long-term antiarrhythmia drug treatment--stand-by therapy for atrial fibrillation].

Journal: MMW Fortschritte der Medizin 20100218

Title: Acute propafenone toxicity after two exposures at standard dosing.

Journal: The Canadian journal of cardiology 20100101

Title: [Atrioventricular nodal reciprocal tachycardia: classification, clinical manifestations, diagnosis, and treatment].

Journal: Kardiologiia 20100101

Title: Syncope, widened QRS interval, and left ventricular systolic depression: coincident with propafenone therapy for atrial fibrillation.

Journal: Texas Heart Institute journal 20100101

Title: Propafenone overdose: cardiac arrest and full recovery.

Journal: Cardiology journal 20100101

Title: [Efficacy of amiodarone versus propafenone in the prevention of rhythm disorders in patients after aortocoronary bypass surgery].

Journal: Anesteziologiia i reanimatologiia 20100101

Title: Atrial tachycardia with 1:1 atrioventricular conduction precipitated by propafenone.

Journal: Emergency medicine journal : EMJ 20091201

Title: Enantioselective analysis of R- and S-propafenone in plasma by HPLC applying column switching and liquid-liquid extraction.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091101

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: [Effectiveness of D,L-sotalol in post-ablative atrial arrhythmias in patients with atrial fibrillation treated with radiofrequency ablation].

Journal: Orvosi hetilap 20090906

Title: Acute intoxication with propafenone and trimethoprim-sulfamethoxazole in a case of suicide attempt.

Journal: Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir 20090901

Title: [Life-threatening ventricular arrhythmia during simultaneous administration of propafenone and sotatol].

Journal: Kardiologia polska 20090801

Title: An acute experimental model demonstrating 2 different forms of sustained atrial tachyarrhythmias.

Journal: Circulation. Arrhythmia and electrophysiology 20090801

Title: Enantioselective plasma protein binding of propafenone: mechanism, drug interaction, and species difference.

Journal: Chirality 20090701

Title: Development of a novel HPLC-MS/MS method for the determination of aconitine and its application to in vitro and rat microdialysis samples.

Journal: Biomedical chromatography : BMC 20090701

Title: The effect of pretreatment with renin-angiotensin-aldosterone system blockers on cardioversion success and acute recurrence of atrial fibrillation.

Journal: International journal of clinical practice 20090701

Title: New pharmacological strategies for the treatment of atrial fibrillation.

Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 20090701

Title: A case of myotonic dystrophy presenting with ventricular tachycardia and atrial fibrillation.

Journal: Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir 20090701

Title: Effects of antiarrhythmic drugs on the hyperpolarization-activated cyclic nucleotide-gated channel current.

Journal: Journal of pharmacological sciences 20090601

Title: Recent advances in the development of P-gp inhibitors.

Journal: Anti-cancer agents in medicinal chemistry 20090501

Title: Giant P waves after pharmacological cardioversion of atrial fibrillation.

Journal: Internal and emergency medicine 20090401

Title: Use of propafenone for conversion of chronic atrial fibrillation in horses.

Journal: American journal of veterinary research 20090201

Title: Regulation of antiarrhythmic drug propafenone effects on the c-type Kv1.4 potassium channel by PHo and K+.

Journal: Journal of Korean medical science 20090201

Title: Determination of propafenone hydrochloride by flow-injection analysis coupled with resonance light scattering detection.

Journal: Luminescence : the journal of biological and chemical luminescence 20090101

Title: Comparative bioavailability of propafenone after administration of a magistral suspension vs. commercial tablets in healthy volunteers.

Journal: Arzneimittel-Forschung 20090101

Title: Neutropenia and cutaneous lesions secondary to propafenone.

Journal: European journal of dermatology : EJD 20090101

Title: Clinical evidence of the antiarrhythmic effect of a magistral suspension of propafenone: a case report.

Journal: Archivos de cardiologia de Mexico 20090101

Title: Is newer better? Propafenone versus quinidine for conversion of atrial fibrillation.

Journal: Cardiology journal 20090101

Title: Efficacy and tolerability of oral propafenone versus quinidine in the treatment of recent onset atrial fibrillation: A randomized, prospective study.

Journal: Cardiology journal 20090101

Title: [Preventive strategy for atrial fibrillation in arterial hypertension].

Journal: Klinicheskaia meditsina 20090101

Title: Extemporaneous suspension of propafenone: attending lack of pediatric formulations in Mexico.

Journal: Pediatric cardiology 20081101

Title: Pharmacology of the short QT syndrome N588K-hERG K+ channel mutation: differential impact on selected class I and class III antiarrhythmic drugs.

Journal: British journal of pharmacology 20081101

Title: [Proarrhythmic effect of propafenone in patients with atrial fibrillation and atrial flutter].

Journal: Kardiologia polska 20081101

Title: Successful conversion of recent-onset atrial fibrillation by sequential administration of up to three antiarrhythmic drugs.

Journal: Clinical cardiology 20081001

Title: Absence of protective effect of renin-angiotensin system inhibitors on atrial fibrillation development: insights from the Canadian Trial of Atrial Fibrillation (CTAF).

Journal: The Canadian journal of cardiology 20080901

Title: I was diagnosed with paroxysmal atrial fibrillation three years ago, ablation proved unsuccessful. My blood pressure and cholesterol are in a healthy range and I have experienced no AFib manifestations since beginning a medication regimen that includes Rythmol. Do I need a stress thallium test to check blood flow if I'm on Rythmol?

Journal: Heart advisor 20080901

Title: Propafenone for the prevention of atrial tachyarrhythmias after cardiac surgery: a randomized, double-blind placebo-controlled trial.

Journal: Clinical pharmacology and therapeutics 20080701

Title: Atrial fibrillation, pharmacological cardioversion and topical ophthalmic beta-blocker use.

Journal: International journal of cardiology 20080606

Title: Controversies in the 'pill in the pocket' approach to atrial fibrillation.

Journal: Internal and emergency medicine 20080601

Title: [The comparison between the efficiency of different anti-arrhythmic agents in preventing postoperative atrial fibrillation after open heart surgery].

Journal: Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20080601

Title: Effect of amiodarone on Kv1.4 channel C-type inactivation: comparison of its effects with those induced by propafenone and verapamil.

Journal: Die Pharmazie 20080601

Title: Adverse effects of propafenone after long-term therapy with the addition of citalopram.

Journal: The American journal of geriatric pharmacotherapy 20080601

Title: Transient syncope, left bundle branch block and first degree atrioventricular block after 'pill-in-the-pocket' administration.

Journal: International journal of cardiology 20080507

Title: New spray congealing atomizer for the microencapsulation of highly concentrated solid and liquid substances.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080501

Title: Empirical kinetic model of propafenone release from Hot Air Coating microparticles.

Journal: International journal of pharmaceutics 20080402

Title: Propafenone-induced psoriasis.

Journal: Clinical and experimental dermatology 20080301

Title: Venlafaxine-propafenone interaction resulting in hallucinations and psychomotor agitation.

Journal: The Annals of pharmacotherapy 20080301

Title: Comparative evaluation of effect of valsartan/amlodipine and atenolol/amlodipine combinations on atrial fibrillation recurrence in hypertensive patients with type 2 diabetes mellitus.

Journal: Journal of cardiovascular pharmacology 20080301

Title: Atrial-selective sodium channel block as a strategy for suppression of atrial fibrillation.

Journal: Annals of the New York Academy of Sciences 20080301

Title: Propafenone-induced Brugada-like ECG changes mistaken as acute myocardial infarction.

Journal: Emergency medicine journal : EMJ 20080201

Title: [Ventricular fibrillation and Brugada-like ECG pattern during propafenone treatment].

Journal: Kardiologia polska 20080201

Title: Atrial antifibrillatory effects of structurally distinct IKur blockers 3-[(dimethylamino)methyl]-6-methoxy-2-methyl-4-phenylisoquinolin-1(2H)-one and 2-phenyl-1,1-dipyridin-3-yl-2-pyrrolidin-1-yl-ethanol in dogs with underlying heart failure.

Journal: The Journal of pharmacology and experimental therapeutics 20080101

Title: A randomized comparison of amiodarone and class IC antiarrhythmic drugs to treat atrial fibrillation in patients paced for sinus node disease: the Prevention Investigation and Treatment: A Group for Observation and Research on Atrial arrhythmias (PITAGORA) trial.

Journal: American heart journal 20080101

Title: Nanostructure-initiator mass spectrometry: a protocol for preparing and applying NIMS surfaces for high-sensitivity mass analysis.

Journal: Nature protocols 20080101

Title: [Impact of electrical shock waveform and paddle positions on efficacy of direct current cardioversion for atrial fibrillation].

Journal: Medicina (Kaunas, Lithuania) 20080101

Title: Can QRS Widening be a result of propafenone overdose?

Journal: Progress in cardiovascular nursing 20080101

Title: Atrial fibrillation (acute onset).

Journal: BMJ clinical evidence 20080101

Title: Deglutition induced atrial tachycardia and atrial fibrillation.

Journal: Pacing and clinical electrophysiology : PACE 20071201

Title: Capillary electrophoresis with laser-induced fluorescence and pre-column derivatization for the analysis of illicit drugs.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070915

Title: Cardiac memory induced by QRS widening due to propafenone toxicity.

Journal: Pacing and clinical electrophysiology : PACE 20070901

Title: A natural variant of the heme-binding signature (R441C) resulting in complete loss of function of CYP2D6.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070801

Title: A comparative study of the efficacy and safety of procainamide versus propafenone versus amiodarone for the conversion of recent-onset atrial fibrillation.

Journal: The American journal of cardiology 20070615

Title: Brugada type electrocardiographic changes induced by concomitant use of lithium and propafenone in patient with Wolff-Parkinson-White syndrome.

Journal: Pacing and clinical electrophysiology : PACE 20070601

Title: Further evidence of inherited long QT syndrome gene mutations in antiarrhythmic drug-associated torsades de pointes.

Journal: Heart rhythm 20070501

Title: Self-organizing maps for identification of new inhibitors of P-glycoprotein.

Journal: Journal of medicinal chemistry 20070405

Title: Efficacy of propafenone in paramyotonia congenita.

Journal: Neurology 20070327

Title: Some patients with paroxysmal atrial fibrillation should carry flecainide or propafenone to self treat.

Journal: BMJ (Clinical research ed.) 20070324

Title: Observations on the safety and effectiveness of dofetilide in patients with paroxysmal atrial fibrillation and normal left ventricular function.

Journal: Journal of cardiovascular pharmacology and therapeutics 20070301

Title: Acute pancreatitis and amiodarone: a case report.

Journal: World journal of gastroenterology 20070214

Title: [Efficacy of intravenous Acehytisine Hydrochloride versus propafenone on terminating paroxysmal supraventricular tachycardia: a double-blinded, randomized multi-center study].

Journal: Zhonghua xin xue guan bing za zhi 20070201

Title: Successful treatment of propafenone, digoxin and warfarin overdosage with plasma exchange therapy and rifampicin.

Journal: Clinical drug investigation 20070101

Title: Does treatment with ACE inhibitors prevent the long term recurrences of lone atrial fibrillation after cardioversion?

Journal: Romanian journal of internal medicine = Revue roumaine de medecine interne 20070101

Title: [Atrial fibrillation].

Journal: Archivos de cardiologia de Mexico 20070101

Title: [Arrhythmias in pregnancy. How and when to treat?].

Journal: Archivos de cardiologia de Mexico 20070101

Title: Inhibitory effects of propafenone on the pharmacokinetics of caffeine in humans.

Journal: Therapeutic drug monitoring 20061201

Title: Effect of propafenone on Kv1.4 inactivation.

Journal: Journal of physiology and biochemistry 20061201

Title: Is circumferential pulmonary vein isolation preferable to stepwise segmental pulmonary vein isolation for patients with paroxysmal atrial fibrillation?

Journal: Circulation journal : official journal of the Japanese Circulation Society 20061101

Title: Pharmacogenetics of antiarrhythmic therapy.

Journal: Expert opinion on pharmacotherapy 20060801

Title: Monomorphic and propafenone-induced polymorphic ventricular tachycardia in Brugada syndrome: a case report.

Journal: Acta cardiologica 20060801

Title: Synthesis of pyrazole-based hybrid molecules: search for potent multidrug resistance modulators.

Journal: Bioorganic & medicinal chemistry 20060715

Title: Bioavailability of an extemporaneous suspension of propafenone made from tablets.

Journal: Biopharmaceutics & drug disposition 20060701

Title: Spectrofluorimetric determination of drugs containing active methylene group using N1-methyl nicotinamide chloride as a fluorigenic agent.

Journal: Chemical & pharmaceutical bulletin 20060701

Title: Searching for new antimalarial therapeutics amongst known drugs.

Journal: Chemical biology & drug design 20060601

Title: Propafenone added to ibutilide increases conversion rates of persistent atrial fibrillation.

Journal: Heart (British Cardiac Society) 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Brugada-type ECG pattern and extreme QRS complex widening with propafenone overdose.

Journal: Journal of cardiovascular electrophysiology 20060501

Title: [Drug treatment of atrial fibrillation].

Journal: MMW Fortschritte der Medizin 20060413

Title: Validated capillary electrophoresis assay for the simultaneous enantioselective determination of propafenone and its major metabolites in biological samples.

Journal: Electrophoresis 20060401

Title: Capillary electrophoretic investigation of the enantioselective metabolism of propafenone by human cytochrome P-450 SUPERSOMES: Evidence for atypical kinetics by CYP2D6 and CYP3A4.

Journal: Electrophoresis 20060401

Title: Combined use of 1C and III agents for highly symptomatic, refractory atrial fibrillation.

Journal: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 20060401

Title: Comparative evaluation of HERG currents and QT intervals following challenge with suspected torsadogenic and nontorsadogenic drugs.

Journal: The Journal of pharmacology and experimental therapeutics 20060301

Title: Drug therapy of paroxysmal atrial fibrillation in the elderly over 75 years old.

Journal: Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20060301

Title: Utility of adjunctive single oral bolus propafenone therapy in patients with atrial defibrillators.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20060301

Title: Broad complex tachycardia during treatment of atrial fibrillation with a 1c antiarrhythmic drug: ventricular or supraventricular proarrhythmia?

Journal: International journal of cardiology 20060208

Title: Urticaria-angioedema reaction caused by propafenone.

Journal: Allergy 20060201

Title: Prediction of drug-drug interactions for AUCoral of high clearance drug from in vitro data: utilization of a microtiter plate assay and a dispersion model.

Journal: Current drug metabolism 20060201

Title: Amiodarone versus Sotalol and Propafenone for prevention of immediate recurrence of atrial fibrillation after internal cardioversion: importance of P wave analysis.

Journal: International journal of cardiology 20060113

Title: Exercise-induced left bundle branch block and propafenone administration.

Journal: International journal of cardiology 20060113

Title: [Preventive efficacy of propafenone, its effect on functional state of the heart during long-term treatment of patients with paroxysmal atrioventricular arrhythmias].

Journal: Kardiologiia 20060101

Title: In vivo antiarrhythmic and cardiac electrophysiologic effects of a novel diphenylphosphine oxide IKur blocker (2-isopropyl-5-methylcyclohexyl) diphenylphosphine oxide.

Journal: The Journal of pharmacology and experimental therapeutics 20051201

Title: Comparison of intravenous ibutilide vs. propafenone for rapid termination of recent onset atrial fibrillation.

Journal: International journal of clinical practice 20051201

Title: [Atrial flutter after orthotopic heart transplantation due to recipient-to-donor transatrial conduction].

Journal: Herzschrittmachertherapie & Elektrophysiologie 20051201

Title: 'Pseudosinus rhythm': what is the mechanism?

Journal: Journal of cardiovascular electrophysiology 20051201

Title: Atrial fibrillation (recent onset).

Journal: Clinical evidence 20051201

Title: [Atrial flutter and fibrillation].

Journal: Praxis 20051109

Title: Effect of porosity on the release kinetics of propafenone-loaded PEG-g-PLA nanoparticles.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20051003

Title: Brugada syndrome, manifested by propafenone induced ST segment elevation.

Journal: Emergency medicine journal : EMJ 20051001

Title: Efficacy and safety of ibutilide for cardioversion of atrial flutter and fibrillation in patients receiving amiodarone or propafenone.

Journal: Pacing and clinical electrophysiology : PACE 20050901

Title: Stunning of the left atrium after pharmacological cardioversion of atrial fibrillation.

Journal: Kardiologia polska 20050901

Title: State-dependent block of human cardiac hNav1.5 sodium channels by propafenone.

Journal: The Journal of membrane biology 20050901

Title: Interaction field based and hologram based QSAR analysis of propafenone-type modulators of multidrug resistance.

Journal: Medicinal chemistry (Shariqah (United Arab Emirates)) 20050901

Title: Blocking characteristics of hKv1.5 and hKv4.3/hKChIP2.2 after administration of the novel antiarrhythmic compound AZD7009.

Journal: Journal of cardiovascular pharmacology 20050701

Title: Nonlinear pharmacokinetics of propafenone in rats and humans: application of a substrate depletion assay using hepatocytes for assessment of nonlinearity.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050601

Title: [Pharmacogenetic study of the response to flecainide and propafenone in patients with atrial fibrillation].

Journal: Revista espanola de cardiologia 20050601

Title: Class I antiarrhythmics inhibit Na+ absorption and Cl- secretion in rabbit descending colon epithelium.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20050601

Title: [Outpatient treatment of recurrent atrial fibrillation with the 'pill-in-the-pocket' approach: practical aspects].

Journal: Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20050601

Title: Usefulness of hepatocytes for evaluating the genetic polymorphism of CYP2D6 substrates.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20050601

Title: Respiratory distress in a young infant.

Journal: Clinical pediatrics 20050501

Title: Hybrid therapy with right atrial catheter ablation and previously ineffective antiarrhythmic drugs for the management of atrial fibrillation.

Journal: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 20050401

Title: [Psoriasis worsened by propafenone].

Journal: Annales de dermatologie et de venereologie 20050401

Title: [Immediate cardioversion of atrial fibrillation and atrial flutter lasting less than 90 days by ibutilide versus propafenone: a multicenter study].

Journal: Zhonghua yi xue za zhi 20050330

Title: The 'pill-in-the-pocket' approach to atrial fibrillation.

Journal: The New England journal of medicine 20050317

Title: The 'pill-in-the-pocket' approach to atrial fibrillation.

Journal: The New England journal of medicine 20050317

Title: Propafenone-induced acute generalized exanthematous pustulosis.

Journal: International journal of dermatology 20050301

Title: Characterisation of (R/S)-propafenone and its metabolites as substrates and inhibitors of P-glycoprotein.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20050301

Title: Can recent-onset atrial fibrillation be safely and successfully treated with self-administered antiarrhythmic drugs?

Journal: Nature clinical practice. Cardiovascular medicine 20050301

Title: P-glycoprotein substrate binding domains are located at the transmembrane domain/transmembrane domain interfaces: a combined photoaffinity labeling-protein homology modeling approach.

Journal: Molecular pharmacology 20050201

Title: Short QT syndrome: mechanisms, diagnosis and treatment.

Journal: Nature clinical practice. Cardiovascular medicine 20050201

Title: Pilsicainide in breast milk from a mother: comparison with disopyramide and propafenone.

Journal: British journal of clinical pharmacology 20050101

Title: Clinical comparison of ibutilide and propafenone for converting atrial flutter.

Journal: Cardiovascular drugs and therapy 20050101

Title: Targeting drug-efflux pumps -- a pharmacoinformatic approach.

Journal: Acta biochimica Polonica 20050101

Title: Sotalol versus propafenone for long-term maintenance of normal sinus rhythm in patients with recurrent symptomatic atrial fibrillation.

Journal: The American journal of cardiology 20041215

Title: Outpatient treatment of recent-onset atrial fibrillation with the 'pill-in-the-pocket' approach.

Journal: The New England journal of medicine 20041202

Title: A three-dimensional model for the substrate binding domain of the multidrug ATP binding cassette transporter LmrA.

Journal: Molecular pharmacology 20041101

Title: The low-potency, voltage-dependent HERG blocker propafenone--molecular determinants and drug trapping.

Journal: Molecular pharmacology 20041101

Title: Flecainide and propafenone induced ST-segment elevation in patients with atrial fibrillation: clue to specificity of Brugada-type electrocardiographic changes.

Journal: The American journal of cardiology 20041101

Title: Different clinical courses and predictors of atrial fibrillation occurrence after transisthmic ablation in patients with preablation lone atrial flutter, coexistent atrial fibrillation, and drug induced atrial flutter.

Journal: Pacing and clinical electrophysiology : PACE 20041101

Title: [Propafenone hepatotoxicity].

Journal: Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 20041001

Title: Limitations to antiarrhythmic drug use in patients with atrial fibrillation.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20040928

Title: Evaluation of KCB-328, a new IKr blocking antiarrhythmic agent in pacing induced canine atrial fibrillation.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20040901

Title: Effectiveness of oral propafenone for the prevention of atrial fibrillation after coronary artery bypass grafting.

Journal: The American journal of cardiology 20040901

Title: A rapid HPLC assay for the simultaneous determination of propafenone and its major metabolites in human serum.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20040901

Title: Ibutilide added to propafenone for the conversion of atrial fibrillation and atrial flutter.

Journal: Journal of the American College of Cardiology 20040818

Title: Use of ibutilide in cardioversion of patients with atrial fibrillation or atrial flutter treated with class IC agents.

Journal: Journal of the American College of Cardiology 20040818

Title: Atrial-selective antiarrhythmic actions of novel Ikur vs. Ikr, Iks, and IKAch class Ic drugs and beta blockers in pigs.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20040701

Title: [Intravenous propafenone for conversion of atrial fibrillation in the emergency room].

Journal: Harefuah 20040701

Title: Efficacy of substituting innovator propafenone for its generic formulation in patients with atrial fibrillation.

Journal: The American journal of cardiology 20040615

Title: Lead identification for modulators of multidrug resistance based on in silico screening with a pharmacophoric feature model.

Journal: Archiv der Pharmazie 20040601

Title: Intramolecular distribution of hydrophobicity influences pharmacological activity of propafenone-type MDR modulators.

Journal: Archiv der Pharmazie 20040601

Title: Efficacy of propafenone for maintaining sinus rhythm in patients with recent onset or persistent atrial fibrillation after conversion: a randomized, placebo-controlled study.

Journal: Acta cardiologica 20040601

Title: Atrial fibrillation (acute).

Journal: Clinical evidence 20040601

Title: [Treatment of atrial fibrillation in a Hungarian hospital department of cardiologic internal medicine at the turn of the millennium].

Journal: Orvosi hetilap 20040509

Title: Typical counterclockwise atrial flutter occurring despite absence of the inferior vena cava.

Journal: Heart rhythm 20040501

Title: Metabolism of propafenone and verapamil by cryopreserved human, rat, mouse and dog hepatocytes: comparison with metabolism in vivo.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20040401

Title: Atrial fibrillation: rate control often better than rhythm control.

Journal: Prescrire international 20040401

Title: Quantitative modelling of interaction of propafenone with sodium channels in cardiac cells.

Journal: Medical & biological engineering & computing 20040301

Title: Enantioselective assay of S+ - and R- -propafenone in human urine by using RP-HPLC with pre-column chiral derivatization.

Journal: Journal of Zhejiang University. Science 20040201

Title: Long-term maintenance of normal sinus rhythm in patients with current symptomatic atrial fibrillation: amiodarone vs propafenone, both in low doses.

Journal: Chest 20040201

Title: Propafenone and its metabolites preferentially inhibit IKr in rabbit ventricular myocytes.

Journal: The Journal of pharmacology and experimental therapeutics 20040101

Title: Ventricular tachycardia as a presenting symptom in a child with thrombotic thrombocytopenic purpura.

Journal: Thrombosis and haemostasis 20040101

Title: High-throughput screening for the assessment of time-dependent inhibitions of new drug candidates on recombinant CYP2D6 and CYP3A4 using a single concentration method.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20040101

Title: [Interaction between ipriflavone and other drugs in metabolism in vitro].

Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20040101

Title: Effects of propafenone associated with propofol on myocardial contractility, heart rate, coronary flow, and the incidence of arrhythmia in isolated hearts of rats.

Journal: Arquivos brasileiros de cardiologia 20040101

Title: Acute toxicity of propafenone in a case of suicidal attempt.

Journal: Bratislavske lekarske listy 20040101

Title: Zebrafish embryos express an orthologue of HERG and are sensitive toward a range of QT-prolonging drugs inducing severe arrhythmia.

Journal: Toxicology and applied pharmacology 20031215

Title: Reproducible efficacy of loading oral propafenone in restoring sinus rhythm in patients with paroxysmal atrial fibrillation.

Journal: The American journal of cardiology 20031201

Title: Influence of CYP2D6*10B genotype on pharmacokinetics of propafenone enantiomers in Chinese subjects.

Journal: Acta pharmacologica Sinica 20031201

Title: Transient platypnea-orthodeoxia-like syndrome induced by propafenone overdose in a young woman with Ebstein's anomaly.

Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20031201

Title: Minipig as a model for drug metabolism in man: comparison of in vitro and in vivo metabolism of propafenone.

Journal: Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20031201

Title: Atrial fibrillation (acute).

Journal: Clinical evidence 20031201

Title: Three-dimensional quantitative structure-activity relationship analysis of propafenone-type multidrug resistance modulators: influence of variable selection on test set predictivity.

Journal: Journal of medicinal chemistry 20031106

Title: A subset of highly effective propafenone-type multidrug resistance modulators lacks effects on cardiac action potential and mechanical twitch parameters of rat papillary muscles.

Journal: The Journal of pharmacology and experimental therapeutics 20031101

Title: Efficacy and safety of sustained-release propafenone (propafenone SR) for patients with atrial fibrillation.

Journal: The American journal of cardiology 20031015

Title: Pharmacological treatment of young children with permanent junctional reciprocating tachycardia.

Journal: Cardiology in the young 20031001

Title: Concentration dependent stereoselectivity of propafenone N-depropylation metabolism with human hepatic recombinant CYP1A2.

Journal: Die Pharmazie 20030901

Title: Cost evaluation of rhythm control methods for atrial fibrillation: evidence from CTAF.

Journal: Cardiac electrophysiology review 20030901

Title: Quality of life variables in the selection of rate versus rhythm control in patients with atrial fibrillation: observations from the Canadian Trial of Atrial Fibrillation.

Journal: Cardiac electrophysiology review 20030901

Title: Facilitating electrical cardioversion of persistant atrial fibrillation by antiarrhythmic drugs: update on clinical trial results.

Journal: Cardiac electrophysiology review 20030901

Title: A novel two-pore domain K+ channel, TRESK, is localized in the spinal cord.

Journal: The Journal of biological chemistry 20030725

Title: Transient intraventricular conduction delay associated with concurrent intake of propafenone and antineoplastic agents.

Journal: Cardiovascular drugs and therapy 20030701

Title: Safety and feasibility of a clinical pathway for the outpatient initiation of antiarrhythmic medications in patients with atrial fibrillation or atrial flutter.

Journal: The American journal of cardiology 20030615

Title: Rate-control versus conversion strategy in postoperative atrial fibrillation: trial design and pilot study results.

Journal: Cardiac electrophysiology review 20030601

Title: Effects of acute ischemia, early extrabeats and propafenone on complex activation patterns in intact and ischemic canine hearts.

Journal: Life sciences 20030502

Title: Old and new antiarrhythmic drugs for converting and maintaining sinus rhythm in atrial fibrillation: comparative efficacy and results of trials.

Journal: The American journal of cardiology 20030320

Title: Pharmacologic and nonpharmacologic options to maintain sinus rhythm: guideline-based and new approaches.

Journal: The American journal of cardiology 20030320

Title: Excitable gap composition in the presence of antiarrhythmic drugs in common human atrial flutter.

Journal: The Canadian journal of cardiology 20030315

Title: Molecular site of action of the antiarrhythmic drug propafenone at the voltage-operated potassium channel Kv2.1.

Journal: Molecular pharmacology 20030301

Title: Effects of propafenone and its main metabolite, 5-hydroxypropafenone, on HERG channels.

Journal: Cardiovascular research 20030301

Title: Left atrial size after cardioversion for atrial fibrillation: effect of external direct current shock.

Journal: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 20030301

Title: Propafenone versus ibutilide for post operative atrial fibrillation following cardiac surgery: neither strategy improves outcomes compared to rate control alone (the PIPAF study).

Journal: Medical science monitor : international medical journal of experimental and clinical research 20030301

Title: Effects of a series of dihydroanthracene derivatives on drug efflux in multidrug resistant cancer cells.

Journal: European journal of medicinal chemistry 20030301

Title: Propafenone hepatotoxicity: report of two new cases.

Journal: Digestive diseases and sciences 20030201

Title: Stereoselectivity in trans-tramadol metabolism and trans-O-demethyltramadol formation in rat liver microsomes.

Journal: Acta pharmacologica Sinica 20030101

Title: New multidrug resistance reversal agents.

Journal: Current drug targets 20030101

Title: Intracardiac low-energy versus transthoracic high-energy direct-current cardioversion of atrial fibrillation: a randomised comparison.

Journal: Cardiology 20030101

Title: Electrophysiological mapping and histological examinations of the swine atrium with sustained (> or =24 h) atrial fibrillation: a suitable animal model for studying human atrial fibrillation.

Journal: Cardiology 20030101

Title: Unintentional pediatric overdose of propafenone.

Journal: The Annals of pharmacotherapy 20030101

Title: Long-term follow-up of sudden cardiac arrest survivors and electrophysiologically guided antiarrhythmic therapy.

Journal: Cardiology 20030101

Title: MCASE study of the multidrug resistance reversal activity of propafenone analogs.

Journal: Journal of computer-aided molecular design 20030101

Title: Fatal propafenone overdoses: case reports and a review of the literature.

Journal: Journal of analytical toxicology 20030101

Title: [Propafenone poisoning].

Journal: Therapie 20030101

Title: [Fatal poisoning with propafenone: a case report documented with blood concentration levels].

Journal: Therapie 20030101

Title: Efficacy and safety of propafenone sustained release in the prophylaxis of symptomatic paroxysmal atrial fibrillation (The European Rythmol/Rytmonorm Atrial Fibrillation Trial [ERAFT] Study).

Journal: The American journal of cardiology 20021215

Title: Human variability in polymorphic CYP2D6 metabolism: is the kinetic default uncertainty factor adequate?

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20021101

Title: Effect of CYP2D6*10 genotype on propafenone pharmacodynamics in Chinese patients with ventricular arrhythmia.

Journal: Acta pharmacologica Sinica 20021101

Title: Similarity based SAR (SIBAR) as tool for early ADME profiling.

Journal: Journal of computer-aided molecular design 20021101

Title: New insights into the mechanisms and management of atrial fibrillation.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20021029

Title: Beta-adrenergic stimulation modulates the sodium current block by propafenone in rat ventricular myocardium.

Journal: Journal of electrocardiology 20021001

Title: Long-term clinical significance of frequent and complex ventricular tachyarrhythmias in trained athletes.

Journal: Journal of the American College of Cardiology 20020807

Title: Congenital junctional ectopic tachycardia in children and adolescents: a 20 year experience based study.

Journal: Heart (British Cardiac Society) 20020801

Title: Inhibition of the current of heterologously expressed HERG potassium channels by flecainide and comparison with quinidine, propafenone and lignocaine.

Journal: British journal of pharmacology 20020701

Title: Amiodarone: pearl or peril?

Journal: European heart journal 20020701

Title: Amiodarone reduces procedures and costs related to atrial fibrillation in a controlled clinical trial.

Journal: European heart journal 20020701

Title: [Proarrhythmic effects of propafenone in a woman with hepatopathy: is it always a simple drug in clinical practice?].

Journal: Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20020701

Title: Propafenone-related cholestatic hepatitis in an elderly patient.

Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20020701

Title: Intermittent Brugada syndrome misdiagnosed as acute myocardial infarction and unmasked with propafenone.

Journal: Heart (British Cardiac Society) 20020601

Title: An evaluation of the strategy of maintenance of sinus rhythm by antiarrhythmic drug therapy after ablation and pacing therapy in patients with paroxysmal atrial fibrillation.

Journal: European heart journal 20020601

Title: [The treatment of postoperative junctional ectopic tachycardia].

Journal: Anales espanoles de pediatria 20020601

Title: Quality of life improves with treatment in the Canadian Trial of Atrial Fibrillation.

Journal: American heart journal 20020601

Title: [Efficacy and tolerance of propafenone after correction of atrial fibrillation: PEPS pharmaco-epidemiologic study].

Journal: Archives des maladies du coeur et des vaisseaux 20020601

Title: [Structure and activity relationship of propafenone and alkylesters of 2-and 4-[(3-propylamino-2-hydroxy)-propoxy]-phenylcarbamic acid].

Journal: Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20020501

Title: Paroxysmal supraventricular tachycardia induced by oral stimulation: a case report and review of swallow-induced dysrhythmias.

Journal: The Journal of emergency medicine 20020501

Title: Effect of propafenone on the contractile activity of Latissimus dorsi muscle isolated in an organ chamber: experimental study in rats.

Journal: Arquivos brasileiros de cardiologia 20020301

Title: Oral loading with propafenone for conversion of recent-onset atrial fibrillation: a review on in-hospital treatment.

Journal: Drugs 20020101

Title: [Disclosure of 'Brugada's syndrome' with intravenous propafenone].

Journal: Archivos de cardiologia de Mexico 20020101

Title: Exercise-induced bidirectional ventricular tachycardia with alternating right and left bundle branch block-type patterns--a case report.

Journal: Angiology 20020101

Title: [Hepatic toxicity of propafenone: a case description].

Journal: Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna 20020101

Title: [Pharmacological cardioversion of atrial fibrillation with intravenous and oral propafenone].

Journal: Medicina (Kaunas, Lithuania) 20020101

Title: Chiral metabolism of propafenone in rat hepatic microsomes treated with two inducers.

Journal: World journal of gastroenterology 20011215

Title: Late-breaking clinical trials at the American Heart Association's scientific sessions 2001.

Journal: Circulation 20011120

Title: Propafenone modulates potassium channel activities of vascular smooth muscle from rat portal veins.

Journal: The Journal of pharmacology and experimental therapeutics 20011101

Title: Giant inverted T waves.

Journal: American journal of critical care : an official publication, American Association of Critical-Care Nurses 20011101

Title: Applications of liquid chromatography-tandem mass spectrometry in drug and biomedical analyses.

Journal: Clinica chimica acta; international journal of clinical chemistry 20011101

Title: [Liver function test impairment induced by propafenone in a 73 year old woman].

Journal: Harefuah 20011101

Title: The effect of propafenone on premature ventricular contractions (PVC): an analysis based on heart rate dependency of PVCs.

Journal: Japanese heart journal 20011101

Title: Non-sustained ventricular tachycardia due to low-dose orphenadrine.

Journal: The American journal of medicine 20011001

Title: Stereoselective metabolism of propafenone by human liver CYP3A4 expressed in transgenic Chinese hamster CHL cells lines.

Journal: Acta pharmacologica Sinica 20011001

Title: Simultaneous modeling of pharmacokinetics and pharmacodynamics of propafenone in healthy subjects.

Journal: Acta pharmacologica Sinica 20011001

Title: Long-term efficacy and safety of propafenone and sotalol for the maintenance of sinus rhythm after conversion of recurrent symptomatic atrial fibrillation.

Journal: The American journal of cardiology 20010915

Title: Transient outward current inhibition by propafenone and 5-hydroxypropafenone in cultured neonatal rat ventricular myocytes.

Journal: Journal of cardiovascular pharmacology 20010901

Title: Visual compatibility of sodium nitroprusside with other injectable medications given to pediatric patients.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20010801

Title: [Comparison of efficacy, safety and cost-effectiveness of intravenous versus oral propafenone in paroxysmal atrial fibrillation].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20010801

Title: Efficacy and safety of dofetilide in the prevention of symptomatic episodes of paroxysmal supraventricular tachycardia: a 6-month double-blind comparison with propafenone and placebo.

Journal: American heart journal 20010701

Title: The influence of CYP2D6 polymorphism on the antiarrhythmic efficacy of propafenone in patients with paroxysmal atrial fibrillation during 3 months propafenone prophylactic treatment.

Journal: International journal of clinical pharmacology and therapeutics 20010701

Title: Altered values of heart rate variability in patients with relapse of atrial fibrillation during the first week after electrical cardioversion: preliminary data.

Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20010601

Title: Class IC antiarrhythmic drug induced atrial flutter: electrocardiographic and electrophysiological findings and their importance for long term outcome after right atrial isthmus ablation.

Journal: Heart (British Cardiac Society) 20010401

Title: Effects of propafenone on anisotropic conduction properties within the three-dimensional structure of the canine ventricular wall.

Journal: Basic research in cardiology 20010401

Title: Blocking effects of the antiarrhythmic drug propafenone on the HERG potassium channel.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20010401

Title: Electrophysiologic effects and efficacy of intravenous propafenone in terminating atrioventricular reentrant tachycardia in children.

Journal: The American journal of cardiology 20010315

Title: [Acute cholestatic hepatitis caused by propafenone. Report of a case and review of the literature].

Journal: Recenti progressi in medicina 20010301

Title: Global distribution of atrial ectopic foci triggering recurrence of atrial tachyarrhythmia after electrical cardioversion of long-standing atrial fibrillation: a bi-atrial basket mapping study.

Journal: Journal of the American College of Cardiology 20010301

Title: Single oral loading dose of propafenone for pharmacological cardioversion of recent-onset atrial fibrillation.

Journal: Journal of the American College of Cardiology 20010201

Title: Differential effects of dofetilide, amiodarone, and class lc drugs on left and right atrial refractoriness and left atrial vulnerability in pigs.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20010201

Title: Intravenous antiarrhythmic agents.

Journal: Current opinion in cardiology 20010101

Title: Evaluation of CYP2D6 oxidation of dextromethorphan and propafenone in a Chinese population with atrial fibrillation.

Journal: Journal of clinical pharmacology 20010101

Title: Efficacy of sequential antiarrhythmic treatment in sinus rhythm maintenance after successful electrocardioversion in patients with chronic non-valvular atrial fibrillation.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20010101

Title: [Effectiveness and side effects of the treatment with propafenone and flecainide for recent-onset atrial fibrillation].

Journal: Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20010101

Title: Pharmacologic conversion of atrial fibrillation: a systematic review of available evidence.

Journal: Progress in cardiovascular diseases 20010101

Title: Algorithmic complexity. A new approach of non-linear algorithms for the analysis of atrial signals from multipolar basket catheter.

Journal: Annali dell'Istituto superiore di sanita 20010101

Title: An organic psychosis due to a venlafaxine-propafenone interaction.

Journal: International journal of psychiatry in medicine 20010101

Title: Propafenone-induced ataxia: report of three cases.

Journal: The American journal of the medical sciences 20000801

Title: Propiverine-induced Parkinsonism: a case report and a pharmacokinetic/pharmacodynamic study in mice.

Journal: Pharmaceutical research 20000501

Title: Orthodromic tachycardia with atrioventricular dissociation: evidence for a nodoventricular (Mahaim) fiber.

Journal: Pacing and clinical electrophysiology : PACE 20000201

Title: Persistent atrial flutter in patients treated for atrial fibrillation with amiodarone and propafenone: electrophysiologic characteristics, radiofrequency catheter ablation, and risk prediction.

Journal: Journal of cardiovascular electrophysiology 19990901

Title: Comparison of propafenone versus procainamide for the acute treatment of atrial fibrillation after cardiac surgery.

Journal: The American journal of cardiology 19990801

Title: Effects of propafenone and 5-hydroxy-propafenone on hKv1.5 channels.

Journal: British journal of pharmacology 19981101

Title: Atrial flutter with 1:1 atrioventricular conduction caused by propafenone.

Journal: Pacing and clinical electrophysiology : PACE 19981001

Title: [Circulatory arrest after combined intravenous drugs for the treatment of orthodromic circular tachycardia of Wolff-Parkinson-White syndrome].

Journal: Revista espanola de cardiologia 19970901

Title: Propafenone for conversion and prophylaxis of atrial fibrillation. Propafenone Atrial Fibrillation Trial Investigators.

Journal: The American journal of cardiology 19970215

Title: Safety and tolerability of long-term propafenone therapy for supraventricular tachyarrhythmias. The Propafenone Multicenter Study Group.

Journal: The American journal of cardiology 19960815

Title: Propafenone versus disopyramide for maintenance of sinus rhythm after electrical cardioversion of chronic atrial fibrillation: a randomized, double-blind study. PRODIS Study Group.

Journal: Cardiovascular drugs and therapy 19960501

Title: Comparisons of oral propafenone and quinidine as an initial treatment option in patients with symptomatic paroxysmal atrial fibrillation: a double-blind, randomized trial.

Journal: Journal of internal medicine 19960301

Title: Probable propafenone-induced transient global amnesia.

Journal: The Annals of pharmacotherapy 19950601

Title: Propafenone-induced peripheral neuropathy.

Journal: Mayo Clinic proceedings 19950501

Title: [Persistent atrial flutter induced by propafenone (Rytmonorm)].

Journal: Orvosi hetilap 19940814

Title: Myoclonus associated with propafenone.

Journal: BMJ (Clinical research ed.) 19940108

Title: Propafenone-induced liver injury: report of a case and review of the literature.

Journal: Gastroenterology 19930501

Title: Normal left ventricular function does not protect against propafenone-induced incessant ventricular tachycardia.

Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 19930401

Title: [Prevention of paroxysmal atrial fibrillation with propafenone after withdrawal of amiodarone because of side effects].

Journal: La Clinica terapeutica 19930401

Title: Proarrhythmic effects of class Ic drugs.

Journal: Clinical therapeutics 19930101

Title: Electrophysiological and electropharmacological studies in pre-excitation syndromes: results with propafenone therapy and isoproterenol infusion testing.

Journal: European heart journal 19921101

Title: Propafenone-induced torsade de pointes: cross-reactivity with quinidine.

Journal: Pacing and clinical electrophysiology : PACE 19911101

Title: Metoprolol-induced delirium perpetuated by propafenone.

Journal: American family physician 19911001

Title: Malignant ventricular tachycardia during propafenone treatment in a child with junctional automatic tachycardia: effectiveness of intravenous molar sodium lactate.

Journal: Pacing and clinical electrophysiology : PACE 19910501

Title: The use of associated propafenone in patients with amiodarone-resistant ventricular tachycardia.

Journal: International journal of cardiology 19910501

Title: [Hemolytic reaction resulting from propafenone administration].

Journal: Zhonghua nei ke za zhi 19910401

Title: Exacerbation of myasthenia by propafenone.

Journal: Journal of neurology, neurosurgery, and psychiatry 19910401

Title: Atrial flutter in patients treated for atrial fibrillation with propafenone.

Journal: The American journal of cardiology 19900915

Title: Changes in cardiac output determined by continuous-wave Doppler echocardiography during propafenone or mexiletine drug testing.

Journal: The American journal of cardiology 19900215

Title: [Myoclonic encephalopathy caused by propafenone].

Journal: Therapie 19900101

Title: Congestive heart failure induced by six of the newer antiarrhythmic drugs.

Journal: Journal of the American College of Cardiology 19891101

Title: Cardioprotective effects of various class I antiarrhythmic drugs in canine hearts.

Journal: Journal of the American College of Cardiology 19890701

Title: Symptomatic sinus node dysfunction associated with the use of propafenone.

Journal: The American journal of cardiology 19880901

Title: Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, propafenone, diltiazem, and sparteine.

Journal: Klinische Wochenschrift 19871215

Title: [Intense symptomatic bradycardia caused by sinoauricular block: severe adverse reaction caused by propafenone].

Journal: Medicina clinica 19871010

Title: Enhanced antiarrhythmic efficacy of propafenone when used in combination with procainamide or quinidine.

Journal: American heart journal 19870901

Title: [Anti-arrhythmia efficacy of propafenone in children. Apropos of 30 cases].

Journal: Archives des maladies du coeur et des vaisseaux 19870801

Title: [Fibrillation and atrial flutter. Immediate control and conversion to sinus rhythm with intravenous propafenone].

Journal: Giornale italiano di cardiologia 19870801

Title: Double-blind study of intravenous propafenone for paroxysmal supraventricular reentrant tachycardia.

Journal: Journal of the American College of Cardiology 19870601

Title: Myasthenia-like syndrome induced by cardiovascular agents. Report of a case.

Journal: Italian journal of neurological sciences 19870401

Title: Sustained ventricular tachycardia occurring during propafenone therapy.

Journal: Acta cardiologica 19870101

Title: Torsade de pointes ventricular tachycardia in a hypothyroid patient treated with propafenone.

Journal: The Canadian journal of cardiology 19870101

Title: Demonstration of beta adrenoceptor blockade by propafenone hydrochloride: clinical pharmacologic, radioligand binding and adenylate cyclase activation studies.

Journal: The Journal of pharmacology and experimental therapeutics 19840201

Title: Drug interactions with amiodarone.

Journal: American heart journal 19831001

Title: http://en.wikipedia.org/wiki/Propafenone

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:34183-22-7 Molecular Formula|34183-22-7 MDL|34183-22-7 SMILES|34183-22-7 1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one hydrochloride