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3521-62-8,MFCD00084691
Catalog No.:AA019FSW

3521-62-8 | Erythromycin estolate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5g
95
in stock  
$24.00   $17.00
- +
25g
95%
in stock  
$62.00   $44.00
- +
100g
95%
in stock  
$178.00   $125.00
- +
500g
95%
in stock  
$677.00   $474.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA019FSW
Chemical Name:
Erythromycin estolate
CAS Number:
3521-62-8
Molecular Formula:
C52H97NO18S
Molecular Weight:
1056.3875
MDL Number:
MFCD00084691
SMILES:
CCC(=O)O[C@H]1[C@@H](O[C@@H](C[C@@H]1N(C)C)C)O[C@@H]1[C@@H](C)[C@H](O[C@@H]2O[C@@H](C)[C@@H]([C@](C2)(C)OC)O)[C@@H](C)C(=O)O[C@H](CC)[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]1(C)O)C)C)O)(C)O.CCCCCCCCCCCCOS(=O)(=O)O
NSC Number:
757880
Properties
Properties
 
BP:
743℃  
Form:
Solid  
MP:
135-140°C dec.  
Refractive Index:
1.6550 (estimate)  
Solubility:
chloroform: soluble4.0ML, clear, colorless (200 mg + 4.0 mL Chloroform)  
Stability:
Light Sensitive  
Storage:
Room Temperature;  

Computed Properties
 
Complexity:
1550  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
18  
Heavy Atom Count:
72  
Hydrogen Bond Acceptor Count:
19  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
22  

Literature

Title: Integrated systems toxicology approaches identified the possible involvement of ABC transporters pathway in erythromycin estolate-induced liver injury in rat.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20140301

Title: Antibiotics for ureaplasma in the vagina in pregnancy.

Journal: The Cochrane database of systematic reviews 20110907

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Pharmacokinetics of erythromycin after the administration of intravenous and various oral dosage forms to dogs.

Journal: Journal of veterinary pharmacology and therapeutics 20081201

Title: Antibiotics for whooping cough (pertussis).

Journal: The Cochrane database of systematic reviews 20070718

Title: Antibiotics for whooping cough (pertussis).

Journal: The Cochrane database of systematic reviews 20050125

Title: Effect of tetrahydrocurcumin on erythromycin estolate-induced lipid peroxidation in rats.

Journal: Journal of basic and clinical physiology and pharmacology 20050101

Title: Azithromycin is as effective as and better tolerated than erythromycin estolate for the treatment of pertussis.

Journal: Pediatrics 20040701

Title: Protective role of tetrahydrocurcumin against erythromycin estolate-induced hepatotoxicity.

Journal: Pharmacological research 20040501

Title: Protective effect of Sesbania grandiflora against erythromycin estolate-induced hepatotoxicity.

Journal: Therapie 20030101

Title: Effect of chlorpromazine and erythromycin on bile salt-induced cholestasis in the rat.

Journal: Pharmacology 19790101

Title: David E. Kleiner, et al. Learn more about Erythromycin Estolate. Biomaterials and Medical Device - Associated Infections, 2015

Title: Lu X, et al. Integrated systems toxicology approaches identified the possible involvement of ABC transporters pathway in erythromycin estolate-induced liver injury in rat. Food Chem Toxicol. 2014 Mar;65:343-55.

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