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361547-56-0,MFCD16620956
Catalog No.:AA00I732

361547-56-0 | Methyl 3-(tert-butyldimethylsilyloxy)-2,2-dimethylpropanoate

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250mg
95%
in stock  
$406.00   $284.00
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1g
95%
in stock  
$941.00   $659.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00I732
Chemical Name:
Methyl 3-(tert-butyldimethylsilyloxy)-2,2-dimethylpropanoate
CAS Number:
361547-56-0
Molecular Formula:
C12H26O3Si
Molecular Weight:
246.4185
MDL Number:
MFCD16620956
SMILES:
COC(=O)C(CO[Si](C(C)(C)C)(C)C)(C)C
Properties
Computed Properties
 
Complexity:
252  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
3  
Rotatable Bond Count:
6  

Downstream Synthesis Route

[1]Roth;McClymont[SyntheticCommunications,1992,vol.22,#3,p.411-420]

[2]Hale,KarlJ.;Xiong,Ziyue;Wang,Liping;Manaviazar,Soraya;Mackle,Ryan[OrganicLetters,2015,vol.17,#2,p.198-201]

[1]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-WO2010/54058,2010,A1Locationinpatent:Page/Pagecolumn80

[2]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-WO2011/22473,2011,A1Locationinpatent:Page/Pagecolumn179

[3]Locationinpatent:schemeortableRowbottom,MartinW.;Faraoni,Raffaella;Chao,Qi;Campbell,BrianT.;Lai,AndiliyG.;Setti,Eduardo;Ezawa,Maiko;Sprankle,KellyG.;Abraham,Sunny;Tran,Lan;Struss,Brian;Gibney,Michael;Armstrong,RobertC.;Gunawardane,RuwanthiN.;Nepomuceno,RonaldR.;Valenta,Ianina;Hua,Helen;Gardner,MichaelF.;Cramer,MerrylD.;Gitnick,Dana;Insko,DarrenE.;Apuy,JuliusL.;Jones-Bolin,Susan;Ghose,ArupK.;Herbertz,Torsten;Ator,MarkA.;Dorsey,BruceD.;Ruggeri,Bruce;Williams,Michael;Bhagwat,Shripad;James,Joyce;Holladay,MarkW.[JournalofMedicinalChemistry,2012,vol.55,#3,p.1082-1105]

[4]CurrentPatentAssignee:PFIZERINC-WO2014/78325,2014,A1Locationinpatent:Paragraph00571

[5]CurrentPatentAssignee:PFIZERINC-WO2014/78408,2014,A1Locationinpatent:Paragraph00502

[6]CurrentPatentAssignee:PFIZERINC-WO2014/78331,2014,A1Locationinpatent:Paragraph00700

[7]Hale,KarlJ.;Xiong,Ziyue;Wang,Liping;Manaviazar,Soraya;Mackle,Ryan[OrganicLetters,2015,vol.17,#2,p.198-201]

[8]Shi,Bairu;Merten,Sandra;Wong,DavidK.Y.;Chu,JohnC.K.;Liu,LokLok;Lam,SzeKui;Jäger,Anne;Wong,Wing-Tak;Chiu,Pauline;Metz,Peter[AdvancedSynthesisandCatalysis,2009,vol.351,#18,p.3128-3132]

[9]CurrentPatentAssignee:NOVARTISAG;Novartis(w/oSandoz)-WO2010/66684,2010,A2Locationinpatent:Page/Pagecolumn52

[10]Roth;McClymont[SyntheticCommunications,1992,vol.22,#3,p.411-420]

[11]Regan,John;Capolino,Alison;Cirillo,PierF.;Gilmore,Thomas;Graham,AnneG.;Hickey,Eugene;Kroe,RachelR.;Madwed,Jeffrey;Moriak,Monica;Nelson,Richard;Pargellis,ChristopherA.;Swinamer,Alan;Torcellini,Carol;Tsang,Michele;Moss,Neil[JournalofMedicinalChemistry,2003,vol.46,#22,p.4676-4686]

[12]CurrentPatentAssignee:PFIZERINC-WO2009/15000,2009,A1Locationinpatent:Page/Pagecolumn23

[13]CurrentPatentAssignee:PFIZERINC-WO2012/158413,2012,A2Locationinpatent:Page/Pagecolumn102

[14]CurrentPatentAssignee:PFIZERINC-WO2014/78322,2014,A1Locationinpatent:Paragraph00387

[15]CurrentPatentAssignee:PFIZERINC-WO2014/78328,2014,A1Locationinpatent:Paragraph00499

[16]CurrentPatentAssignee:PFIZERINC-WO2014/78454,2014,A1Locationinpatent:Paragraph00640

[1]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-WO2010/54058,2010,A1Locationinpatent:Page/Pagecolumn80

[2]Locationinpatent:experimentalpartRowbottom,MartinW.;Faraoni,Raffaella;Chao,Qi;Campbell,BrianT.;Lai,AndiliyG.;Setti,Eduardo;Ezawa,Maiko;Sprankle,KellyG.;Abraham,Sunny;Tran,Lan;Struss,Brian;Gibney,Michael;Armstrong,RobertC.;Gunawardane,RuwanthiN.;Nepomuceno,RonaldR.;Valenta,Ianina;Hua,Helen;Gardner,MichaelF.;Cramer,MerrylD.;Gitnick,Dana;Insko,DarrenE.;Apuy,JuliusL.;Jones-Bolin,Susan;Ghose,ArupK.;Herbertz,Torsten;Ator,MarkA.;Dorsey,BruceD.;Ruggeri,Bruce;Williams,Michael;Bhagwat,Shripad;James,Joyce;Holladay,MarkW.[JournalofMedicinalChemistry,2012,vol.55,#3,p.1082-1105]

[3]Regan,John;Capolino,Alison;Cirillo,PierF.;Gilmore,Thomas;Graham,AnneG.;Hickey,Eugene;Kroe,RachelR.;Madwed,Jeffrey;Moriak,Monica;Nelson,Richard;Pargellis,ChristopherA.;Swinamer,Alan;Torcellini,Carol;Tsang,Michele;Moss,Neil[JournalofMedicinalChemistry,2003,vol.46,#22,p.4676-4686]

[4]CurrentPatentAssignee:PFIZERINC-WO2009/15000,2009,A1Locationinpatent:Page/Pagecolumn23

361547-56-0   
1-5-(2-hydroxy-1,1-dimethyl-ethyl)-2-<i>p</i>-tolyl-2<i>H</i>-pyrazol-3-yl-3-4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl-urea 

[1]Regan,John;Capolino,Alison;Cirillo,PierF.;Gilmore,Thomas;Graham,AnneG.;Hickey,Eugene;Kroe,RachelR.;Madwed,Jeffrey;Moriak,Monica;Nelson,Richard;Pargellis,ChristopherA.;Swinamer,Alan;Torcellini,Carol;Tsang,Michele;Moss,Neil[JournalofMedicinalChemistry,2003,vol.46,#22,p.4676-4686]

[1]Regan,John;Capolino,Alison;Cirillo,PierF.;Gilmore,Thomas;Graham,AnneG.;Hickey,Eugene;Kroe,RachelR.;Madwed,Jeffrey;Moriak,Monica;Nelson,Richard;Pargellis,ChristopherA.;Swinamer,Alan;Torcellini,Carol;Tsang,Michele;Moss,Neil[JournalofMedicinalChemistry,2003,vol.46,#22,p.4676-4686]

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Tags:361547-56-0 Molecular Formula|361547-56-0 MDL|361547-56-0 SMILES|361547-56-0 Methyl 3-(tert-butyldimethylsilyloxy)-2,2-dimethylpropanoate