Home Amines 3621-36-1
3621-36-1,MFCD01546522
Catalog No.:AA00C6G0

3621-36-1 | Columbamine

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Purity
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1mg
98%
in stock  
$42.00   $29.00
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25mg
98%
in stock  
$811.00   $568.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00C6G0
Chemical Name:
Columbamine
CAS Number:
3621-36-1
Molecular Formula:
C20H20NO4+
Molecular Weight:
338.3771
MDL Number:
MFCD01546522
SMILES:
COc1cc2CC[n+]3c(c2cc1O)cc1c(c3)c(OC)c(cc1)OC
Properties
Properties
 
Form:
Solid  
MP:
280-282℃ (methanol )  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
461  
Covalently-Bonded Unit Count:
1  
Formal Charge:
1  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  
XLogP3:
3.4  

Literature

Title: Columbamine suppresses the proliferation and neovascularization of metastatic osteosarcoma U2OS cells with low cytotoxicity.

Journal: Toxicology letters 20121217

Title: Quality evaluation and species differentiation of Rhizoma coptidis by using proton nuclear magnetic resonance spectroscopy.

Journal: Analytica chimica acta 20121017

Title: Coptis chinensis inflorescence extract protection against ultraviolet-B-induced phototoxicity, and HPLC-MS analysis of its chemical composition.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120701

Title: Metabolic discrimination of rhizoma coptidis from different species using 1H NMR spectroscopy and principal component analysis.

Journal: Planta medica 20120401

Title: Cytotoxicity and antihyperglycemic effect of minor constituents from Rhizoma Coptis in HepG2 cells.

Journal: Fitoterapia 20120101

Title: Anti-Inflammatory Activities of a Chinese Herbal Formula IBS-20 In Vitro and In Vivo.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: [Chemical constituents from Corydalis yanhusuo].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120101

Title: [Dynamic accumulation of effective components and biomass of Coptis chinensis in Hongya county].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110801

Title: Metabolites of protoberberine alkaloids in human urine following oral administration of Coptidis Rhizoma decoction.

Journal: Planta medica 20101101

Title: [Simultaneous determination of six alkaloids in Coptis chinensis of different regions by RP-HPLC].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20101001

Title: Anti-inflammatory and anti-nociceptive activities of compounds from Tinospora sagittata (Oliv.) Gagnep.

Journal: Archives of pharmacal research 20100701

Title: Alkaloids from Fissistigma latifolium (Dunal) Merr.

Journal: Molecules (Basel, Switzerland) 20100624

Title: Metabolic diversification of benzylisoquinoline alkaloid biosynthesis through the introduction of a branch pathway in Eschscholzia californica.

Journal: Plant & cell physiology 20100601

Title: Quaternary alkaloids of Argemone mexicana.

Journal: Pharmaceutical biology 20100201

Title: Dig1 protects against cell death provoked by glyphosate-based herbicides in human liver cell lines.

Journal: Journal of occupational medicine and toxicology (London, England) 20100101

Title: [A new flavonoid glucoside from Huanglianjiedutang decoction].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090501

Title: Inhibitory Effects of Coptidis rhizoma and Berberine on Cocaine-induced Sensitization.

Journal: Evidence-based complementary and alternative medicine : eCAM 20090301

Title: Significant differences in alkaloid content of Coptis chinensis (Huanglian), from its related American species.

Journal: Chinese medicine 20090101

Title: [Studies on chemical constituents in the anti-myocardial ischemia effective fraction of Corydalis yanhusuo].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20081101

Title: Isoquinoline alkaloids isolated from Corydalis yanhusuo and their binding affinities at the dopamine D1 receptor.

Journal: Molecules (Basel, Switzerland) 20080925

Title: [Analysis of the main components of coptis-evodia herb couple by HPLC-DAD-MS].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20080301

Title: Cytochrome P3A4 inhibitors and other constituents of Fibraurea tinctoria.

Journal: Journal of natural products 20071201

Title: High performance liquid chromatography-mass spectrometry analysis of protoberberine alkaloids in medicine herbs.

Journal: Journal of separation science 20070401

Title: Simultaneous determination of eight components in Radix Tinosporae by high-performance liquid chromatography coupled with diode array detector and electrospray tandem mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20070219

Title: Free radical scavenging activity and lipoxygenase inhibition of Mahonia aquifolium extract and isoquinoline alkaloids.

Journal: Journal of inflammation (London, England) 20070101

Title: Characterization of isoquinoline alkaloids, diterpenoids and steroids in the Chinese herb Jin-Guo-Lan (Tinospora sagittata and Tinospora capillipes) by high-performance liquid chromatography/electrospray ionization with multistage mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20060101

Title: Separation of protoberberine quaternary alkaloids from a crude extract of Enantia chlorantha by centrifugal partition chromatography.

Journal: Journal of chromatography. A 20040702

Title: A comparative study on the anti-inflammatory, antinociceptive and antipyretic effects of isoquinoline alkaloids from the roots of Turkish Berberis species.

Journal: Life sciences 20021227

Title: Molecular cloning of columbamine O-methyltransferase from cultured Coptis japonica cells.

Journal: European journal of biochemistry 20021101

Title: Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase.

Journal: Journal of natural products 19910101

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