Home Amines 3685-84-5
3685-84-5,MFCD00012533
Catalog No.:AA0034I8

3685-84-5 | 2-(dimethylamino)ethyl 2-(4-chlorophenoxy)acetate hydrochloride

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1g
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$13.00   $9.00
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5g
98%
in stock  
$19.00   $13.00
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25g
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$58.00   $40.00
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500g
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  • Technical Information
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA0034I8
Chemical Name:
2-(dimethylamino)ethyl 2-(4-chlorophenoxy)acetate hydrochloride
CAS Number:
3685-84-5
Molecular Formula:
C12H17Cl2NO3
Molecular Weight:
294.1743
MDL Number:
MFCD00012533
SMILES:
CN(CCOC(=O)COc1ccc(cc1)Cl)C.Cl
Properties
Properties
 
Form:
Solid  
MP:
133-135°C  
Refractive Index:
1.6140 (estimate)  
Storage:
Room Temperature;  

Computed Properties
 
Complexity:
228  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
7  

Literature

Title: Construction and performance characteristics of new ion selective electrodes based on carbon nanotubes for determination of meclofenoxate hydrochloride.

Journal: Analytica chimica acta 20120612

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: A simple and sensitive HPLC method for quantification of the metabolin of meclofenoxate in human plasma.

Journal: Journal of chromatographic science 20100101

Title: Effect of centrophenoxine against rotenone-induced oxidative stress in an animal model of Parkinson's disease.

Journal: Neurochemistry international 20091101

Title: Bioequivalence and pharmacokinetic comparison of a single 200-mg dose of meclofenoxate hydrochloride capsule and tablet formulations in healthy Chinese adult male volunteers: a randomized sequence, open-label, two-period crossover study.

Journal: Clinical therapeutics 20080901

Title: Behavioral alterations in rotenone model of Parkinson's disease: attenuation by co-treatment of centrophenoxine.

Journal: Brain research 20080327

Title: [Effects of piracetam and meclofenoxate on the brain NMDA and nicotinic receptors in mice with different exploratory efficacy in the cross maze test].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20080101

Title: [Effects of nicotinic cholinoreceptor ligands and nootropic drugs on the spontaneous exploratory activity in a labyrinth in mice].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20080101

Title: Further evidence of centrophenoxine mediated protection in aluminium exposed rats by biochemical and light microscopy analysis.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20071201

Title: Kinetic study on the degradation of meclophenoxate hydrochloride in alkaline aqueous solutions by high performance liquid chromatography.

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20070101

Title: Stability-indicating electrochemical methods for the determination of meclophenoxate hydrochloride and pyritinol dihydrochloride using ion-selective membrane electrodes.

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20070101

Title: Reversal of an aluminium induced alteration in redox status in different regions of rat brain by administration of centrophenoxine.

Journal: Molecular and cellular biochemistry 20061001

Title: Evidence for centrophenoxine as a protective drug in aluminium induced behavioral and biochemical alteration in rat brain.

Journal: Molecular and cellular biochemistry 20061001

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Modulatory effects of centrophenoxine on different regions of ageing rat brain.

Journal: Experimental gerontology 20051001

Title: Centrophenoxine improves chronic cerebral ischemia induced cognitive deficit and neuronal degeneration in rats.

Journal: Acta pharmacologica Sinica 20041201

Title: Brain cholinesterases: III. Future perspectives of AD research and clinical practice.

Journal: Medical hypotheses 20040101

Title: Effect of centrophenoxine on water-immersion restraint stress- and chemically-induced gastric ulcers in rats.

Journal: Research communications in molecular pathology and pharmacology 20030101

Title: Pharmacological interventions against aging through the cell plasma membrane: a review of the experimental results obtained in animals and humans.

Journal: Annals of the New York Academy of Sciences 20020401

Title: Can nootropic drugs be effective against the impact of ethanol teratogenicity on cognitive performance?

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20010201

Title: Memory effects of the new derivative of the p-chlorophenoxyacetic acid adafenoxate compared to the effects of some cognition-enhancing drugs in rats.

Journal: Arzneimittel-Forschung 19890901

Title: [Pharmacological analysis of memory disorders of different origins].

Journal: Biulleten' eksperimental'noi biologii i meditsiny 19890601

Title: Effect of nicergoline on learning and memory.

Journal: Methods and findings in experimental and clinical pharmacology 19880701

Title: [Circadian rhythm studies on the prenatal toxic effect of cyclophosphamide and centrophenoxine in Wistar rats].

Journal: Anatomischer Anzeiger 19850101

Title: Mosharrof AH, et al. Effects of meclofenoxate and citicholine on learning and memory in aged rats. Acta Physiol Pharmacol Bulg. 1987;13(4):17-24.

Title: Marcer D, et al. The differential effects of meclofenoxate on memory loss in the elderly. Age Ageing. 1977 May;6(2):123-31.

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