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Title: Neuroprotective effect of linagliptin against cuprizone-induced demyelination and behavioural dysfunction in mice: A pivotal role of AMPK/SIRT1 and JAK2/STAT3/NF-κB signalling pathway modulation.
Journal: Toxicology and applied pharmacology 20180801
Title: Global gene expression profiles in brain regions reflecting abnormal neuronal and glial functions targeting myelin sheaths after 28-day exposure to cuprizone in rats.
Journal: Toxicology and applied pharmacology 20161101
Title: Developmental cuprizone exposure impairs oligodendrocyte lineages differentially in cortical and white matter tissues and suppresses glutamatergic neurogenesis signals and synaptic plasticity in the hippocampal dentate gyrus of rats.
Journal: Toxicology and applied pharmacology 20160101
Title: Cuprizone decreases intermediate and late-stage progenitor cells in hippocampal neurogenesis of rats in a framework of 28-day oral dose toxicity study.
Journal: Toxicology and applied pharmacology 20150915
Title: Developmental exposure to cuprizone reduces intermediate-stage progenitor cells and cholinergic signals in the hippocampal neurogenesis in rat offspring.
Journal: Toxicology letters 20150505
Title: Enhanced accumulation of Kir4.1 protein, but not mRNA, in a murine model of cuprizone-induced demyelination.
Journal: Brain research 20131106
Title: Sildenafil (Viagra®) down regulates cytokines and prevents demyelination in a cuprizone-induced MS mouse model.
Journal: Cytokine 20121101
Title: Reduced astrocytic NF-κB activation by laquinimod protects from cuprizone-induced demyelination.
Journal: Acta neuropathologica 20120901
Title: Quetiapine enhances oligodendrocyte regeneration and myelin repair after cuprizone-induced demyelination.
Journal: Schizophrenia research 20120601
Title: The cyclooxygenase-2 pathway via the PGE₂ EP2 receptor contributes to oligodendrocytes apoptosis in cuprizone-induced demyelination.
Journal: Journal of neurochemistry 20120501
Title: BACE1 in central nervous system myelination revisited.
Journal: Molecular psychiatry 20120301
Title: Expression of retinoid X receptor β is induced in astrocytes during corpus callosum demyelination.
Journal: Journal of chemical neuroanatomy 20120301
Title: Olesoxime accelerates myelination and promotes repair in models of demyelination.
Journal: Annals of neurology 20120201
Title: Magnetic resonance imaging and histological evidence for the blockade of cuprizone-induced demyelination in C57BL/6 mice.
Journal: Neuroscience 20120127
Title: Fibroblast growth factor 1 (FGFR1) modulation regulates repair capacity of oligodendrocyte progenitor cells following chronic demyelination.
Journal: Neurobiology of disease 20120101
Title: Galanin transgenic mice with elevated circulating galanin levels alleviate demyelination in a cuprizone-induced MS mouse model.
Journal: PloS one 20120101
Title: Sphingosine 1-phosphate receptor modulator fingolimod (FTY720) does not promote remyelination in vivo.
Journal: Molecular and cellular neurosciences 20110901
Title: The hippocampal fimbria of cuprizone-treated animals as a structure for studying neuroprotection in multiple sclerosis.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20110801
Title: Corticosteroids impair remyelination in the corpus callosum of cuprizone-treated mice.
Journal: Journal of neuroendocrinology 20110701
Title: Time-dependent changes in the brain arachidonic acid cascade during cuprizone-induced demyelination and remyelination.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20110701
Title: Inhibition of 5-lipoxygenase activity in mice during cuprizone-induced demyelination attenuates neuroinflammation, motor dysfunction and axonal damage.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20110701
Title: Neurobiological effects of sphingosine 1-phosphate receptor modulation in the cuprizone model.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110501
Title: Remyelination is altered by bone morphogenic protein signaling in demyelinated lesions.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110323
Title: Longitudinal near-infrared imaging of myelination.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110216
Title: Gas6 increases myelination by oligodendrocytes and its deficiency delays recovery following cuprizone-induced demyelination.
Journal: PloS one 20110101
Title: Spatial and temporal profiles of growth factor expression during CNS demyelination reveal the dynamics of repair priming.
Journal: PloS one 20110101
Title: Dietary vitamin D3 supplements reduce demyelination in the cuprizone model.
Journal: PloS one 20110101
Title: Influence of methylprednisolone on magnetic resonance and histological measures during cuprizone-induced demyelination.
Journal: Neuroscience letters 20101008
Title: Modulation of bone morphogenic protein signalling alters numbers of astrocytes and oligodendroglia in the subventricular zone during cuprizone-induced demyelination.
Journal: Journal of neurochemistry 20101001
Title: Beneficial effects of minocycline on cuprizone induced cortical demyelination.
Journal: Neurochemical research 20100901
Title: Cuprizone neurotoxicity, copper deficiency and neurodegeneration.
Journal: Neurotoxicology 20100901
Title: 17beta-estradiol protects male mice from cuprizone-induced demyelination and oligodendrocyte loss.
Journal: Neurobiology of disease 20100801
Title: ADAM12 is expressed by astrocytes during experimental demyelination.
Journal: Brain research 20100422
Title: HDAC1 nuclear export induced by pathological conditions is essential for the onset of axonal damage.
Journal: Nature neuroscience 20100201
Title: Effects of fumaric acids on cuprizone induced central nervous system de- and remyelination in the mouse.
Journal: PloS one 20100101
Title: GAS6 enhances repair following cuprizone-induced demyelination.
Journal: PloS one 20100101
Title: Demyelination in the juvenile period, but not in adulthood, leads to long-lasting cognitive impairment and deficient social interaction in mice.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20090831
Title: 17beta-estradiol and progesterone prevent cuprizone provoked demyelination of corpus callosum in male mice.
Journal: Glia 20090601
Title: Partial inhibition of proteasome activity enhances remyelination after cuprizone-induced demyelination.
Journal: Experimental neurology 20090601
Title: Discoidin domain receptor 1, a tyrosine kinase receptor, is upregulated in an experimental model of remyelination and during oligodendrocyte differentiation in vitro.
Journal: Journal of molecular neuroscience : MN 20090501
Title: Statin therapy inhibits remyelination in the central nervous system.
Journal: The American journal of pathology 20090501
Title: Behavioral and neurobiological changes in C57BL/6 mice exposed to cuprizone.
Journal: Behavioral neuroscience 20090401
Title: Recovery from chronic demyelination by thyroid hormone therapy: myelinogenesis induction and assessment by diffusion tensor magnetic resonance imaging.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20081224
Title: Activation of inflammatory response by a combination of growth factors in cuprizone-induced demyelinated brain leads to myelin repair.
Journal: Neurochemical research 20081201
Title: Quetiapine alleviates the cuprizone-induced white matter pathology in the brain of C57BL/6 mouse.
Journal: Schizophrenia research 20081201
Title: Axl-/- mice have delayed recovery and prolonged axonal damage following cuprizone toxicity.
Journal: Brain research 20081113
Title: Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency.
Journal: Nature neuroscience 20080901
Title: Thyroid hormones promote differentiation of oligodendrocyte progenitor cells and improve remyelination after cuprizone-induced demyelination.
Journal: Experimental neurology 20080801
Title: Inhibition of p53 transcriptional activity: a potential target for future development of therapeutic strategies for primary demyelination.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080611
Title: Gas6 deficiency increases oligodendrocyte loss and microglial activation in response to cuprizone-induced demyelination.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080514
Title: MRI identification of the rostral-caudal pattern of pathology within the corpus callosum in the cuprizone mouse model.
Journal: Journal of magnetic resonance imaging : JMRI 20080301
Title: Effects of acute and repeated exposure to lipopolysaccharide on cytokine and corticosterone production during remyelination.
Journal: Brain, behavior, and immunity 20071001
Title: Microglial recruitment, activation, and proliferation in response to primary demyelination.
Journal: The American journal of pathology 20070501
Title: The neurotoxic effect of cuprizone on oligodendrocytes depends on the presence of pro-inflammatory cytokines secreted by microglia.
Journal: Neurochemical research 20070201
Title: Combination of growth factors enhances remyelination in a cuprizone-induced demyelination mouse model.
Journal: Neurochemical research 20070101
Title: Implications of protease M/neurosin in myelination during experimental demyelination and remyelination.
Journal: Neuroscience letters 20060925
Title: A novel fluorescent probe that is brain permeable and selectively binds to myelin.
Journal: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20060901
Title: Imaging the peripheral benzodiazepine receptor response in central nervous system demyelination and remyelination.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060601
Title: Dominant-negative beta1 integrin mice have region-specific myelin defects accompanied by alterations in MAPK activity.
Journal: Glia 20060601
Title: Remyelination after cuprizone-induced demyelination in the rat is stimulated by apotransferrin.
Journal: Experimental neurology 20060401
Title: Copper and zinc dismetabolism in the mouse brain upon chronic cuprizone treatment.
Journal: Cellular and molecular life sciences : CMLS 20050701
Title: Astroglial-derived lymphotoxin-alpha exacerbates inflammation and demyelination, but not remyelination.
Journal: Glia 20050101
Title: Hyperphosphorylation and aggregation of tau in experimental autoimmune encephalomyelitis.
Journal: The Journal of biological chemistry 20041231
Title: bHLH transcription factor Olig1 is required to repair demyelinated lesions in the CNS.
Journal: Science (New York, N.Y.) 20041217
Title: Induction of hyperphosphorylated tau in primary rat cortical neuron cultures mediated by oxidative stress and glycogen synthase kinase-3.
Journal: Journal of Alzheimer's disease : JAD 20041201
Title: K+ channel blockade impairs remyelination in the cuprizone model.
Journal: Glia 20041101
Title: Peripheral benzodiazepine receptor imaging in CNS demyelination: functional implications of anatomical and cellular localization.
Journal: Brain : a journal of neurology 20040601
Title: Oligodendrocytes and progenitors become progressively depleted within chronically demyelinated lesions.
Journal: The American journal of pathology 20040501
Title: Alterations in metabolism and gene expression in brain regions during cuprizone-induced demyelination and remyelination.
Journal: Journal of neurochemistry 20020701
Title: The protective role of nitric oxide in a neurotoxicant-induced demyelinating model.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20020101
Title: Cuprizone and piperonyl butoxide, proposed inhibitors of T-cell function, attenuate experimental allergic encephalomyelitis in SJL mice.
Journal: Journal of neuroimmunology 20011001
Title: Interleukin-1beta promotes repair of the CNS.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010915
Title: Cerebroside synthesis as a measure of the rate of remyelination following cuprizone-induced demyelination in brain.
Journal: Journal of neurochemistry 20010501
Title: Role of copper ions and cytochrome P450 in the vasodilator actions of the nitroxyl anion generator, Angeli's salt, on rat aorta.
Journal: European journal of pharmacology 20010202
Title: [Transition metals and nitric oxide production in human endothelial cells].
Journal: Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie 20010101
Title: A comparison of spongiosis induced in the brain by hexachlorophene, cuprizone and triethyl tin in the Sprague-Dawley rat.
Journal: Human & experimental toxicology 19911101
