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375815-87-5,MFCD08460603
Catalog No.:AA00BXLX

375815-87-5 | Varenicline tartrate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$7.00   $5.00
- +
5mg
98%
in stock  
$15.00   $11.00
- +
10mg
98%
in stock  
$19.00   $14.00
- +
25mg
98%
in stock  
$24.00   $17.00
- +
100mg
98%
in stock  
$36.00   $25.00
- +
1g
98%
in stock  
$193.00   $135.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00BXLX
Chemical Name:
Varenicline tartrate
CAS Number:
375815-87-5
Molecular Formula:
C17H19N3O6
Molecular Weight:
361.3493
MDL Number:
MFCD08460603
SMILES:
N1C[C@@H]2C[C@H](C1)c1c2cc2c(c1)nccn2.O[C@H]([C@H](C(=O)O)O)C(=O)O
Properties
Computed Properties
 
Complexity:
388  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
2  

Downstream Synthesis Route

[1]CurrentPatentAssignee:ZHEJIANGCHARIOTEERPHARMACEUTICALCOLTD-CN113980020,2022,ALocationinpatent:Paragraph0035-0062

[2]CurrentPatentAssignee:KYUNGDONGPHARM.CO.,LTD.-KR101781352,2017,B1Locationinpatent:Paragraph0100-0101

[3]CurrentPatentAssignee:MEDICHEM,S.A.-US2012/4239,2012,A1Locationinpatent:Page/Pagecolumn12

[4]CurrentPatentAssignee:PFIZERINC-WO2007/110730,2007,A2Locationinpatent:Page/Pagecolumn10

[5]CurrentPatentAssignee:SEIDEENGELBERT;TEVAPHARMACEUTICALINDUSTRIESLTD.-WO2010/23561,2010,A1Locationinpatent:Page/Pagecolumn19

[6]CurrentPatentAssignee:ALKEMLAB;ALKEMLABORATORIES-WO2011/80758,2011,A2Locationinpatent:Page/Pagecolumn18

[7]CurrentPatentAssignee:TEVAPHARMACEUTICALINDUSTRIESLTD.-WO2011/110954,2011,A1Locationinpatent:Page/Pagecolumn21-22

1-(9,10-dihydro-6H-6,10-methanoazepino4,5-gquinoxaline-8(7H)-yl)-2,2,2,-trifluoroethanone 
  87-69-4    375815-87-5 

[1]CurrentPatentAssignee:MEDICHEM,S.A.-US2012/4239,2012,A1Locationinpatent:Page/Pagecolumn11

[2]CurrentPatentAssignee:PFIZERINC-WO2004/108725,2004,A1Locationinpatent:Page6

[3]CurrentPatentAssignee:MEDICHEM,S.A.-WO2009/65872,2009,A2Locationinpatent:Page/Pagecolumn12-13;14-15;18

[1]CurrentPatentAssignee:MEDICHEM,S.A.-WO2009/101185,2009,A2Locationinpatent:Page/Pagecolumn7

1-(7,8-diamino-4,5-dihydro-1H-1,5-methanobenzodazepin-3(2H)-yl)-2,2,2-trifluoroethanone 
  375815-87-5 

[1]CurrentPatentAssignee:ALKEMLAB;ALKEMLABORATORIES-WO2011/80758,2011,A2

[2]CurrentPatentAssignee:TEVAPHARMACEUTICALINDUSTRIESLTD.-WO2011/110954,2011,A1

Literature

Title: Varenicline promotes endothelial cell migration by lowering vascular endothelial-cadherin levels via the activated α7 nicotinic acetylcholine receptor-mitogen activated protein kinase axis.

Journal: Toxicology 20170901

Title: Varenicline enhances oxidized LDL uptake by increasing expression of LOX-1 and CD36 scavenger receptors through α(7) nAChR in macrophages.

Journal: Toxicology 20170401

Title: Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis.

Journal: Chemical research in toxicology 20150518

Title: Organic cation transporter variation and response to smoking cessation therapies.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20141201

Title: Comparative pathophysiology, toxicology, and human cancer risk assessment of pharmaceutical-induced hibernoma.

Journal: Toxicology and applied pharmacology 20131215

Title: Effects of nicotinic acetylcholine receptor agonists on cognition in rhesus monkeys with a chronic cocaine self-administration history.

Journal: Neuropharmacology 20130101

Title: The effect of smoking cessation pharmacotherapies on pancreatic beta cell function.

Journal: Toxicology and applied pharmacology 20121115

Title: Impact of human D398N single nucleotide polymorphism on intracellular calcium response mediated by α3β4α5 nicotinic acetylcholine receptors.

Journal: Neuropharmacology 20121101

Title: Chronic sazetidine-A at behaviorally active doses does not increase nicotinic cholinergic receptors in rodent brain.

Journal: The Journal of pharmacology and experimental therapeutics 20121101

Title: Strategies to help a smoker who is struggling to quit.

Journal: JAMA 20121017

Title: An economic evaluation based on a randomized placebo-controlled trial of varenicline in smokers with cardiovascular disease: results for Belgium, Spain, Portugal, and Italy.

Journal: European journal of preventive cardiology 20121001

Title: Varenicline decreases nicotine self-administration and cue-induced reinstatement of nicotine-seeking behaviour in rats when a long pretreatment time is used.

Journal: The international journal of neuropsychopharmacology 20121001

Title: Project Impact: a pharmacotherapy pilot trial investigating the abstinence and treatment adherence of Latino light smokers.

Journal: Journal of substance abuse treatment 20121001

Title: Varenicline induced psychosis in schizophrenia.

Journal: The Australian and New Zealand journal of psychiatry 20121001

Title: Varenicline decreases alcohol consumption in heavy-drinking smokers.

Journal: Psychopharmacology 20121001

Title: Effects of 21 days of varenicline versus placebo on smoking behaviors and urges among non-treatment seeking smokers.

Journal: Journal of psychopharmacology (Oxford, England) 20121001

Title: Adverse neuropsychiatric events associated with varenicline use in veterans: a case series.

Journal: Issues in mental health nursing 20121001

Title: Characteristics of COPD smokers and effectiveness and safety of smoking cessation medications.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20120901

Title: Adherence to varenicline among African American smokers: an exploratory analysis comparing plasma concentration, pill count, and self-report.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20120901

Title: Effects of the combination of metyrapone and oxazepam on intravenous nicotine self-administration in rats.

Journal: Psychopharmacology 20120901

Title: Impact of varenicline on cue-specific craving assessed in the natural environment among treatment-seeking smokers.

Journal: Psychopharmacology 20120901

Title: The effects of varenicline on attention and inhibitory control among treatment-seeking smokers.

Journal: Psychopharmacology 20120901

Title: Use of an α3β4 nicotinic acetylcholine receptor subunit concatamer to characterize ganglionic receptor subtypes with specific subunit composition reveals species-specific pharmacologic properties.

Journal: Neuropharmacology 20120901

Title: The antinociceptive effects of nicotinic partial agonists varenicline and sazetidine-A in murine acute and tonic pain models.

Journal: The Journal of pharmacology and experimental therapeutics 20120901

Title: Comparisons of high-dose and combination nicotine replacement therapy, varenicline, and bupropion for smoking cessation: a systematic review and multiple treatment meta-analysis.

Journal: Annals of medicine 20120901

Title: Varenicline for smoking cessation: nausea severity and variation in nicotinic receptor genes.

Journal: The pharmacogenomics journal 20120801

Title: Varenicline is a potent partial agonist at α6β2* nicotinic acetylcholine receptors in rat and monkey striatum.

Journal: The Journal of pharmacology and experimental therapeutics 20120801

Title: Do package inserts reflect symptoms experienced in practice?: assessment using an automated phone pharmacovigilance system with varenicline and zolpidem in a primary care setting.

Journal: Drug safety 20120801

Title: Efficacy and safety of pharmacotherapy for smoking cessation among pregnant smokers: a meta-analysis.

Journal: BJOG : an international journal of obstetrics and gynaecology 20120801

Title: Cost-effectiveness of varenicline versus bupropion, nicotine-replacement therapy, and unaided cessation in Greece.

Journal: Clinical therapeutics 20120801

Title: Health impact of smoking and smoking cessation strategies: current evidence.

Journal: British journal of community nursing 20120801

Title: Does varenicline worsen psychiatric symptoms in patients with schizophrenia or schizoaffective disorder? A review of published studies.

Journal: The Journal of clinical psychiatry 20120801

Title: Structural characterization of binding mode of smoking cessation drugs to nicotinic acetylcholine receptors through study of ligand complexes with acetylcholine-binding protein.

Journal: The Journal of biological chemistry 20120706

Title: Prescribing of nicotine replacement therapy to cardiovascular disease patients in England.

Journal: Addiction (Abingdon, England) 20120701

Title: Varenicline increases in vivo striatal dopamine D2/3 receptor binding: an ultra-high-resolution pinhole [123I]IBZM SPECT study in rats.

Journal: Nuclear medicine and biology 20120701

Title: Epistaxis and other haemorrhagic events associated with the smoking cessation medicine varenicline: a case series from two national pharmacovigilance centres.

Journal: European journal of clinical pharmacology 20120701

Title: Effectiveness of varenicline for smoking cessation at 2 urban academic health centers.

Journal: European journal of internal medicine 20120701

Title: Varenicline blocks β2*-nAChR-mediated response and activates β4*-nAChR-mediated responses in mice in vivo.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20120601

Title: A single administration of low-dose varenicline saturates α4β2* nicotinic acetylcholine receptors in the human brain.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20120601

Title: Pharmacologic characterization of a nicotine-discriminative stimulus in rhesus monkeys.

Journal: The Journal of pharmacology and experimental therapeutics 20120601

Title: A pilot test of a combined tobacco dependence treatment and lung cancer screening program.

Journal: Lung cancer (Amsterdam, Netherlands) 20120501

Title: Very low rate and light smokers: smoking patterns and cessation-related behaviour in England, 2006-11.

Journal: Addiction (Abingdon, England) 20120501

Title: Varenicline potentiates alcohol-induced negative subjective responses and offsets impaired eye movements.

Journal: Alcoholism, clinical and experimental research 20120501

Title: [Effectiveness and safety of varenicline for smoking cessation].

Journal: Deutsche medizinische Wochenschrift (1946) 20120501

Title: A randomized, double-blind, placebo-controlled study evaluating the safety and efficacy of varenicline for smoking cessation in patients with schizophrenia or schizoaffective disorder.

Journal: The Journal of clinical psychiatry 20120501

Title: Nicotine receptor partial agonists for smoking cessation.

Journal: The Cochrane database of systematic reviews 20120418

Title: Changes in health-related quality of life with smoking cessation treatment.

Journal: European journal of public health 20120401

Title: Plasma levels of metabolites of catecholamine in nicotine-dependent patients treated with varenicline.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20120401

Title: Efficacy and tolerability of pharmacotherapies to aid smoking cessation in adolescents.

Journal: Paediatric drugs 20120401

Title: Promoting smoking cessation.

Journal: American family physician 20120315

Title: Cost-effectiveness of tobacco control policies in Vietnam: the case of personal smoking cessation support.

Journal: Addiction (Abingdon, England) 20120301

Title: Varenicline dose dependently enhances responding for nonpharmacological reinforcers and attenuates the reinforcement-enhancing effects of nicotine.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20120301

Title: A randomized placebo-controlled trial of varenicline for smoking cessation allowing flexible quit dates.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20120301

Title: Smoking cessation after brain damage does not lead to increased depression: implications for understanding the psychiatric complications of varenicline.

Journal: Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology 20120301

Title: A randomized trial of varenicline (Chantix) for the treatment of spinocerebellar ataxia type 3.

Journal: Neurology 20120221

Title: Pfizer advertises smoking cessation drug despite health warnings.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20120207

Title: Varenicline versus bupropion XL for smoking cessation in older adolescents: a randomized, double-blind pilot trial.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20120201

Title: Results of an initial clinical trial of varenicline for the treatment of cocaine dependence.

Journal: Drug and alcohol dependence 20120201

Title: Effects of varenicline and bupropion on cognitive processes among nicotine-deprived smokers.

Journal: Experimental and clinical psychopharmacology 20120201

Title: Adjunctive varenicline treatment with antipsychotic medications for cognitive impairments in people with schizophrenia: a randomized double-blind placebo-controlled trial.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20120201

Title: Smoking cessation pharmacogenetics: analysis of varenicline and bupropion in placebo-controlled clinical trials.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20120201

Title: The effects of extended pre-quit varenicline treatment on smoking behavior and short-term abstinence: a randomized clinical trial.

Journal: Clinical pharmacology and therapeutics 20120201

Title: Quitting smoking with varenicline: parallel, randomised efficacy trial in Iran.

Journal: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20120201

Title: Grover disease may result from the impairment of keratinocytic cholinergic receptors.

Journal: Journal of the American Academy of Dermatology 20120201

Title: Systematic review of the cost-effectiveness of varenicline vs. bupropion for smoking cessation.

Journal: International journal of clinical practice 20120201

Title: Cost-effectiveness analysis of varenicline versus existing smoking cessation strategies in Central America and the Caribbean using the BENESCO model.

Journal: Hospital practice (1995) 20120201

Title: Cost analysis of varenicline versus bupropion, nicotine replacement therapy, and unaided cessation in Nicaragua.

Journal: Hospital practice (1995) 20120201

Title: Varenicline: aggression and homicidal ideation.

Journal: Prescrire international 20120201

Title: The pain of giving up smoking.

Journal: International journal of cardiology 20120126

Title: [Smoking cessation in medical practice--new possibilities?].

Journal: Revue medicale suisse 20120125

Title: New reports examine psychiatric risks of varenicline for smoking cessation.

Journal: JAMA 20120111

Title: Varenicline as a smoking cessation aid in schizophrenia: effects on smoking behavior and reward sensitivity.

Journal: Psychopharmacology 20120101

Title: Safety and tolerability of varenicline tartrate (Champix(®)/Chantix(®)) for smoking cessation in HIV-infected subjects: a pilot open-label study.

Journal: AIDS patient care and STDs 20120101

Title: Cardiovascular events in patients taking varenicline: a case series from intensive postmarketing surveillance in New Zealand.

Journal: Drug safety 20120101

Title: Varenicline precipitating psychosis in a patient with no previous psychiatric history: a case report of a Spanish patient who was later diagnosed with paranoid personality disorder.

Journal: Clinical schizophrenia & related psychoses 20120101

Title: Real world evaluation of three models of NHS smoking cessation service in England.

Journal: BMC research notes 20120101

Title: Varenicline in stopping long-term nicotine use.

Journal: The American journal on addictions 20120101

Title: Varenicline.

Journal: Profiles of drug substances, excipients, and related methodology 20120101

Title: Risk of cardiovascular serious adverse events associated with varenicline use for tobacco cessation: systematic review and meta-analysis.

Journal: BMJ (Clinical research ed.) 20120101

Title: Drug-induced liver injury due to varenicline: a case report.

Journal: BMC gastroenterology 20120101

Title: Economic impact of delays in listing decisions by provincial drug plans after a positive Common Drug Review recommendation: the case of a smoking-cessation treatment.

Journal: Healthcare quarterly (Toronto, Ont.) 20120101

Title: Use of the Patient Health Questionnaire-2 to predict suicidal ideations in patients taking varenicline.

Journal: The American journal on addictions 20120101

Title: A novel recruitment message to increase enrollment into a smoking cessation treatment program: preliminary results from a randomized trial.

Journal: Health communication 20111201

Title: Effects of moderate-dose treatment with varenicline on neurobiological and cognitive biomarkers in smokers and nonsmokers with schizophrenia or schizoaffective disorder.

Journal: Archives of general psychiatry 20111201

Title: Tobacco dependence treatment for hospitalized smokers: a randomized, controlled, pilot trial using varenicline.

Journal: Addictive behaviors 20111201

Title: Efficacy of a flexible quit date versus an a priori quit date approach to smoking cessation: a cross-study analysis.

Journal: Addictive behaviors 20111201

Title: A cost-effectiveness model of smoking cessation based on a randomised controlled trial of varenicline versus placebo in patients with chronic obstructive pulmonary disease.

Journal: Expert opinion on pharmacotherapy 20111201

Title: [The evaluation of strengthened psychological and behavioral intervention in smoking cessation clinics].

Journal: Zhonghua nei ke za zhi 20111201

Title: Varenicline prevents affective and cognitive exacerbation during smoking abstinence in male patients with schizophrenia.

Journal: Psychiatry research 20111130

Title: Quantification of nicotine, cotinine, trans-3'-hydroxycotinine and varenicline in human plasma by a sensitive and specific UPLC-tandem mass-spectrometry procedure for a clinical study on smoking cessation.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111115

Title: Unichiral 2-(2'-pyrrolidinyl)-1,4-benzodioxanes: the 2R,2'S diastereomer of the N-methyl-7-hydroxy analogue is a potent α4β2- and α6β2-nicotinic acetylcholine receptor partial agonist.

Journal: Journal of medicinal chemistry 20111110

Title: Varenicline effects on craving, cue reactivity, and smoking reward.

Journal: Psychopharmacology 20111101

Title: Lung function and respiratory symptoms in a 1-year randomized smoking cessation trial of varenicline in COPD patients.

Journal: Respiratory medicine 20111101

Title: The smoking cessation drug varenicline improves deficient P20-N40 inhibition in DBA/2 mice.

Journal: Pharmacology, biochemistry, and behavior 20111101

Title: Effects of varenicline on the reinforcing and discriminative stimulus effects of cocaine in rhesus monkeys.

Journal: The Journal of pharmacology and experimental therapeutics 20111101

Title: [Good effect of varenicline in snuff use cessation. Double-blind placebo controlled comparative study].

Journal: Lakartidningen 20111101

Title: The effect of varenicline on heart rate variability in healthy smokers and nonsmokers.

Journal: Autonomic neuroscience : basic & clinical 20111028

Title: Cost effectiveness of interventions to reduce relapse to smoking following smoking cessation.

Journal: Addiction (Abingdon, England) 20111001

Title: The impact of the introduction of smoke-free legislation on prescribing of stop-smoking medications in England.

Journal: Addiction (Abingdon, England) 20111001

Title: Efficacy of varenicline to prompt quit attempts in smokers not currently trying to quit: a randomized placebo-controlled trial.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20111001

Title: Patterns of nicotinic receptor antagonism: nicotine discrimination studies.

Journal: The Journal of pharmacology and experimental therapeutics 20111001

Title: Varenicline is a potent agonist of the human 5-hydroxytryptamine3 receptor.

Journal: The Journal of pharmacology and experimental therapeutics 20111001

Title: Observational study of safety and efficacy of varenicline for smoking cessation among Filipino smokers.

Journal: Current medical research and opinion 20111001

Title: Nicotine receptor partial agonists for smoking cessation.

Journal: American family physician 20111001

Title: More evidence that varenicline harms the heart.

Journal: The Harvard mental health letter 20111001

Title: A comparison of brain and behavioral effects of varenicline and nicotine in rats.

Journal: Behavioural brain research 20110930

Title: Clinical practice. Treating smokers in the health care setting.

Journal: The New England journal of medicine 20110929

Title: Risk of serious adverse cardiovascular events associated with varenicline: a systematic review and meta-analysis.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20110906

Title: Varenicline for smoking cessation: is it a heartbreaker?

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20110906

Title: Varenicline: quantifying the risk.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20110906

Title: Varenicline: quantifying the risk.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20110906

Title: Varenicline: quantifying the risk.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20110906

Title: Varenicline: quantifying the risk.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20110906

Title: Varenicline: quantifying the risk.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20110906

Title: Varenicline: cardiovascular safety.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20110906

Title: [Abstinence rates with varenicline compared to bupropion and nicotine replacement therapy for quitting smoking in primary care].

Journal: Atencion primaria 20110901

Title: Dissociation between duration of action in the forced swim test in mice and nicotinic acetylcholine receptor occupancy with sazetidine, varenicline, and 5-I-A85380.

Journal: Psychopharmacology 20110901

Title: A pilot clinical trial of varenicline for smoking cessation in black smokers.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20110901

Title: A pilot study of the efficacy of varenicline for the treatment of smokeless tobacco users in Midwestern United States.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20110901

Title: Did the introduction of varenicline in England substitute for or add to the use of other smoking cessation medications?

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20110901

Title: Psychiatric adverse events associated with varenicline: an intensive postmarketing prospective cohort study in New Zealand.

Journal: Drug safety 20110901

Title: In brief: Cardiovascular safety of varenicline (Chantix).

Journal: The Medical letter on drugs and therapeutics 20110822

Title: Varenicline for tobacco dependence: panacea or plight?

Journal: Expert opinion on pharmacotherapy 20110801

Title: [Clinical study of smoking cessation clinic subjects].

Journal: Nihon Jibiinkoka Gakkai kaiho 20110801

Title: Varenicline attenuates cue-induced relapse to alcohol, but not nicotine seeking, while reducing inhibitory response control.

Journal: Psychopharmacology 20110701

Title: Effectiveness of varenicline for smoking cessation: a 1-year follow-up study.

Journal: Journal of substance abuse treatment 20110701

Title: Varenicline, a partial agonist at neuronal nicotinic acetylcholine receptors, reduces nicotine-induced increases in 20% ethanol operant self-administration in Sprague-Dawley rats.

Journal: Addiction biology 20110701

Title: Prescribing of smoking cessation medication in England since the introduction of varenicline.

Journal: Addiction (Abingdon, England) 20110701

Title: The sensitizing effect of acute nicotine on amphetamine-stimulated behavior and dopamine efflux requires activation of β2 subunit-containing nicotinic acetylcholine receptors and glutamate N-methyl-D-aspartate receptors.

Journal: Neuropharmacology 20110601

Title: A preliminary investigation of varenicline for heavy drinking smokers.

Journal: Psychopharmacology 20110601

Title: A double-blind randomized placebo-controlled pilot study of neuropsychiatric adverse events in abstinent smokers treated with varenicline or placebo.

Journal: Biological psychiatry 20110601

Title: Selective α4β2 nicotinic acetylcholine receptor agonists target epigenetic mechanisms in cortical GABAergic neurons.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20110601

Title: Varenicline for smoking cessation in people with schizophrenia: a double blind randomized pilot study.

Journal: Schizophrenia research 20110601

Title: Varenicline induced mania in a 51 year old patient without history of bipolar illness.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20110601

Title: A discrete-event simulation of smoking-cessation strategies based on varenicline pivotal trial data.

Journal: PharmacoEconomics 20110601

Title: A case of late-life onset mania during Varenicline assisted smoking cessation.

Journal: International journal of geriatric psychiatry 20110601

Title: A smoking cessation intervention for thoracic surgery and oncology clinics: a pilot trial.

Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20110601

Title: Varenicline and the evaluation of neuropsychiatric adverse events in smokers.

Journal: Biological psychiatry 20110601

Title: Core modification of cytisine: a modular synthesis.

Journal: Angewandte Chemie (International ed. in English) 20110523

Title: Effects of varenicline on smoking cue–triggered neural and craving responses.

Journal: Archives of general psychiatry 20110501

Title: Nicotinic receptor agonists decrease L-dopa-induced dyskinesias most effectively in partially lesioned parkinsonian rats.

Journal: Neuropharmacology 20110501

Title: Electrophysiological perspectives on the therapeutic use of nicotinic acetylcholine receptor partial agonists.

Journal: The Journal of pharmacology and experimental therapeutics 20110501

Title: Utilization of services in a randomized trial testing phone- and web-based interventions for smoking cessation.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20110501

Title: Adherence to varenicline in the COMPASS smoking cessation intervention trial.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20110501

Title: Treatment of nicotine dependence with Chantix (varenicline).

Journal: Texas dental journal 20110501

Title: Use of varenicline for 4 weeks before quitting smoking: decrease in ad lib smoking and increase in smoking cessation rates.

Journal: Archives of internal medicine 20110425

Title: Smoking cessation interventions: a primer for physicians: Comment on 'Use of varenicline for 4 weeks before quitting smoking'.

Journal: Archives of internal medicine 20110425

Title: [Smoking cessation--assistance for the general practitioner].

Journal: MMW Fortschritte der Medizin 20110407

Title: Pharmacokinetics, safety, and tolerability following multiple oral doses of varenicline under various titration schedules in elderly nonsmokers.

Journal: Journal of clinical pharmacology 20110401

Title: Single- and multiple-dose pharmacokinetics of the selective nicotinic receptor partial agonist, varenicline, in healthy Japanese adult smokers.

Journal: Journal of clinical pharmacology 20110401

Title: A review of cost-effectiveness of varenicline and comparison of cost-effectiveness of treatments for major smoking-related morbidities.

Journal: Journal of evaluation in clinical practice 20110401

Title: Effectiveness of varenicline as an aid to smoking cessation: results of an inter-European observational study.

Journal: Current medical research and opinion 20110401

Title: What justifies a placebo-controlled trial of Varenicline for smoking cessation in patients with COPD?

Journal: Chest 20110401

Title: Effects of varenicline in adult smokers: a multinational, 24-week, randomized, double-blind, placebo-controlled study.

Journal: Clinical therapeutics 20110401

Title: Smoking cessation pharmacotherapy: a concise overview.

Journal: Advance for NPs & PAs 20110401

Title: Breaking free from nicotine dependence. A combination of strategies boosts the odds of success.

Journal: The Harvard mental health letter 20110401

Title: Clinical shorts.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20110322

Title: Synthesis of 2-(substituted phenyl)-3,5,5-trimethylmorpholine analogues and their effects on monoamine uptake, nicotinic acetylcholine receptor function, and behavioral effects of nicotine.

Journal: Journal of medicinal chemistry 20110310

Title: Effects of varenicline on smoking cessation in patients with mild to moderate COPD: a randomized controlled trial.

Journal: Chest 20110301

Title: Abstinence and psychological distress in co-morbid smokers using various pharmacotherapies.

Journal: Drug and alcohol dependence 20110301

Title: The effects of nicotine, varenicline, and cytisine on schedule-controlled responding in mice: differences in α4β2 nicotinic receptor activation.

Journal: European journal of pharmacology 20110301

Title: Nicotine dependence: health consequences, smoking cessation therapies, and pharmacotherapy.

Journal: Primary care 20110301

Title: Interventions for smokeless tobacco use cessation.

Journal: The Cochrane database of systematic reviews 20110216

Title: Nicotine receptor partial agonists for smoking cessation.

Journal: The Cochrane database of systematic reviews 20110216

Title: Varenicline blocks nicotine intake in rats with extended access to nicotine self-administration.

Journal: Psychopharmacology 20110201

Title: Dose-dependent and sustained effects of varenicline on dopamine D2/3 receptor availability in rats.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20110201

Title: Adherence to and reasons for premature discontinuation from stop-smoking medications: data from the ITC Four-Country Survey.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20110201

Title: Australia's experience with varenicline: usage, costs and adverse reactions.

Journal: Addiction (Abingdon, England) 20110201

Title: Adynamic ileus induced by varenicline.

Journal: Current drug safety 20110201

Title: Integrating results from smoking cessation drug research and development into clinical occupational health practice.

Journal: AAOHN journal : official journal of the American Association of Occupational Health Nurses 20110201

Title: Effects of copayment on initiation of smoking cessation pharmacotherapy: an analysis of varenicline reversed claims.

Journal: Clinical therapeutics 20110201

Title: [Pharmacotherapies for nicotine dependence: review of scientific evidence. Spanish Society of Smoking Specialists: recommendations about election and individualization].

Journal: Medicina clinica 20110129

Title: Varenicline for tobacco dependence treatment in recovering alcohol-dependent smokers: an open-label pilot study.

Journal: Journal of substance abuse treatment 20110101

Title: Effect of co-administration of varenicline and antidepressants on extracellular monoamine concentrations in rat prefrontal cortex.

Journal: Neurochemistry international 20110101

Title: Parallel anxiolytic-like effects and upregulation of neuronal nicotinic acetylcholine receptors following chronic nicotine and varenicline.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20110101

Title: Impact of genetic variability in nicotinic acetylcholine receptors on nicotine addiction and smoking cessation treatment.

Journal: Current medicinal chemistry 20110101

Title: Functional interactions of fibrillar and oligomeric amyloid-β with alpha7 nicotinic receptors in Alzheimer's disease.

Journal: Journal of Alzheimer's disease : JAD 20110101

Title: Counselors' knowledge of the adoption of tobacco cessation medications in substance abuse treatment programs.

Journal: The American journal on addictions 20110101

Title: Nicotinic acetylcholine receptors containing the α4 subunit are critical for the nicotine-induced reduction of acute voluntary ethanol consumption.

Journal: Channels (Austin, Tex.) 20110101

Title: Pharmacotherapy for smoking.

Journal: Canadian family physician Medecin de famille canadien 20110101

Title: Usage patterns of stop smoking medications in Australia, Canada, the United Kingdom, and the United States: findings from the 2006-2008 International Tobacco Control (ITC) Four Country Survey.

Journal: International journal of environmental research and public health 20110101

Title: Correlation between willing to smoking cessation and treatment outcome of health care workers in Thailandt.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20110101

Title: Pharmacotherapy for smoking cessation: present and future.

Journal: Current pharmaceutical design 20110101

Title: Culturally-tailored smoking cessation for American Indians: study protocol for a randomized controlled trial.

Journal: Trials 20110101

Title: A manic episode in a 64-year-old man: an adverse effect of varenicline.

Journal: General hospital psychiatry 20110101

Title: The management of tobacco smoking.

Journal: Cardiovascular journal of Africa 20110101

Title: Varenicline induces manic relapse in bipolar disorder.

Journal: General hospital psychiatry 20110101

Title: Gastrointestinal adverse effects of varenicline at maintenance dose: a meta-analysis.

Journal: BMC clinical pharmacology 20110101

Title: Suicidal behavior and depression in smoking cessation treatments.

Journal: PloS one 20110101

Title: Effects of smoking cessation on central blood pressure and arterial stiffness.

Journal: Vascular health and risk management 20110101

Title: Adverse effects and tolerability of medications for the treatment of tobacco use and dependence.

Journal: Drugs 20101224

Title: Nicotine receptor partial agonists for smoking cessation.

Journal: The Cochrane database of systematic reviews 20101208

Title: Drug treatment for users of smokeless tobacco.

Journal: BMJ (Clinical research ed.) 20101206

Title: The high-affinity nAChR partial agonists varenicline and sazetidine-A exhibit reinforcing properties in rats.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20101201

Title: Drug discrimination in methamphetamine-trained rats: effects of cholinergic nicotinic compounds.

Journal: The Journal of pharmacology and experimental therapeutics 20101201

Title: The nicotinic acetylcholine receptor partial agonist varenicline increases the ataxic and sedative-hypnotic effects of acute ethanol administration in C57BL/6J mice.

Journal: Alcoholism, clinical and experimental research 20101201

Title: Nicotine receptors and depression: revisiting and revising the cholinergic hypothesis.

Journal: Trends in pharmacological sciences 20101201

Title: A review of the clinical pharmacokinetics and pharmacodynamics of varenicline for smoking cessation.

Journal: Clinical pharmacokinetics 20101201

Title: Varenicline-induced grand mal seizure.

Journal: Epileptic disorders : international epilepsy journal with videotape 20101201

Title: Thiopurine S-methyltransferase deficiency associated with a novel mutation.

Journal: Inflammatory bowel diseases 20101101

Title: Immediate versus delayed quitting and rates of relapse among smokers treated successfully with varenicline, bupropion SR or placebo.

Journal: Addiction (Abingdon, England) 20101101

Title: Mental health stability in veterans with posttraumatic stress disorder receiving varenicline.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20101101

Title: [Sustainable efficacy of oral varenicline for smoking cessation].

Journal: Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20101101

Title: Comparison of available treatments for tobacco addiction.

Journal: Current psychiatry reports 20101001

Title: A pilot study to assess smokeless tobacco use reduction with varenicline.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20101001

Title: Nicotine gum dependence treated with varenicline--a case report.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20101001

Title: Clinical experience of varenicline for smoking cessation.

Journal: The clinical respiratory journal 20101001

Title: A brief review of pharmacotherapeutic treatment options in smoking cessation: bupropion versus varenicline.

Journal: Journal of the American Academy of Nurse Practitioners 20101001

Title: Relapse prevention in UK Stop Smoking Services: current practice, systematic reviews of effectiveness and cost-effectiveness analysis.

Journal: Health technology assessment (Winchester, England) 20101001

Title: Varenicline (champix)-associated manic relapse in bipolar affective disorder.

Journal: Irish medical journal 20101001

Title: Utilization of the smoking cessation medicine varenicline: an intensive post-marketing study in New Zealand.

Journal: Pharmacoepidemiology and drug safety 20100901

Title: Thoughts and acts of aggression/violence toward others reported in association with varenicline.

Journal: The Annals of pharmacotherapy 20100901

Title: Varenicline treatment for smoking cessation in Asian populations: a pooled analysis of placebo-controlled trials conducted in six Asian countries.

Journal: Current medical research and opinion 20100901

Title: The safety and efficacy of varenicline in cocaine using smokers maintained on methadone: a pilot study.

Journal: The American journal on addictions 20100901

Title: Pharmacoeconomic spotlight on varenicline as an aid to smoking cessation.

Journal: CNS drugs 20100901

Title: Utilization management for smoking cessation pharmacotherapy: varenicline rejected claims analysis.

Journal: The American journal of managed care 20100901

Title: Electroconvulsive therapy (ECT) effective for psychotic recrudescence and suicidality after varenicline adjunctive therapy for smoking cessation in a schizoaffective patient.

Journal: Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20100901

Title: Letter by Smolderen and Pelle regarding article, 'Efficacy and safety of varenicline for smoking cessation in patients with cardiovascular disease: a randomized trial'.

Journal: Circulation 20100831

Title: Drug safety crackdown revs up.

Journal: Nature 20100805

Title: Nicotinic partial agonists varenicline and sazetidine-A have differential effects on affective behavior.

Journal: The Journal of pharmacology and experimental therapeutics 20100801

Title: Varenicline and mecamylamine attenuate locomotor sensitization and cross-sensitization induced by nicotine and morphine in mice.

Journal: Pharmacology, biochemistry, and behavior 20100801

Title: Smoking cessation-recent advances.

Journal: Cardiovascular drugs and therapy 20100801

Title: The use of snus for quitting smoking compared with medicinal products.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20100801

Title: [The management of patients with nicotine dependence - the role of the general practitioners].

Journal: Therapeutische Umschau. Revue therapeutique 20100801

Title: [Medical therapy for smoking cessation].

Journal: Therapeutische Umschau. Revue therapeutique 20100801

Title: [Preventive relapse treatment for tobacco cessation - is it worthwhile?].

Journal: Therapeutische Umschau. Revue therapeutique 20100801

Title: Activation of alpha4* nAChRs is necessary and sufficient for varenicline-induced reduction of alcohol consumption.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100728

Title: Cross-validation of a new procedure for early screening of smoking cessation medications in humans.

Journal: Clinical pharmacology and therapeutics 20100701

Title: Varenicline-induced drug eruption with resulting palmar/plantar hyperhidrosis and dysesthesia.

Journal: Journal of the American Academy of Dermatology 20100701

Title: Predictors of post-treatment relapse to smoking in successful quitters: pooled data from two phase III varenicline trials.

Journal: Drug and alcohol dependence 20100601

Title: Varenicline induced polydipsia and hyponatremia in a patient with schizophrenia.

Journal: Schizophrenia research 20100601

Title: Extinction with varenicline and nornicotine, but not ABT-418, weakens conditioned responding evoked by the interoceptive stimulus effects of nicotine.

Journal: Neuropharmacology 20100601

Title: Varenicline treatment decreases DNMT1 mRNA expression in lymphocytes of schizophrenic patients who are cigarette smokers.

Journal: Schizophrenia research 20100601

Title: Smoking outcome by psychiatric history after behavioral and varenicline treatment.

Journal: Journal of substance abuse treatment 20100601

Title: Characteristics and abstinence outcomes among tobacco quitline enrollees using varenicline or nicotine replacement therapy.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20100601

Title: Mouse model predicts effects of smoking and varenicline on event-related potentials in humans.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20100601

Title: Adherence to treatment for tobacco dependence: association with smoking abstinence and predictors of adherence.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20100601

Title: Varenicline withdrawal-induced delirium with psychosis.

Journal: The American journal of psychiatry 20100601

Title: Varenicline in smoking cessation.

Journal: Expert review of respiratory medicine 20100601

Title: Activation and inhibition of mouse muscle and neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes.

Journal: The Journal of pharmacology and experimental therapeutics 20100501

Title: Varenicline use in patients with mental illness: an update of the evidence.

Journal: Expert opinion on drug safety 20100501

Title: Varenicline's effects on acute smoking behavior and reward and their association with subsequent abstinence.

Journal: Psychopharmacology 20100501

Title: Pre-clinical properties of the alpha4beta2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence.

Journal: British journal of pharmacology 20100501

Title: Behavioral counseling and varenicline treatment for smoking cessation.

Journal: American journal of preventive medicine 20100501

Title: [Pharmacological profile and clinical findings on varenicline tartrate (Champix tablets)].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20100501

Title: Effects of the alpha4beta2 partial agonist varenicline on brain activity and working memory in abstinent smokers.

Journal: Biological psychiatry 20100415

Title: Evaluation of varenicline as an aid to smoking cessation in UK general practice - a THIN database study.

Journal: Current medical research and opinion 20100401

Title: A randomized controlled open comparative trial of varenicline vs nicotine patch in adult smokers: efficacy, safety and withdrawal symptoms (the VN-SEESAW study).

Journal: Circulation journal : official journal of the Japanese Circulation Society 20100401

Title: Pharmacological effects of nonselective and subtype-selective nicotinic acetylcholine receptor agonists in animal models of persistent pain.

Journal: Pain 20100401

Title: Effects of varenicline and mecamylamine on the acquisition, expression, and reinstatement of nicotine-conditioned place preference by drug priming in rats.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20100401

Title: Psychiatric adverse events in randomized, double-blind, placebo-controlled clinical trials of varenicline: a pooled analysis.

Journal: Drug safety 20100401

Title: Varenicline does not increase serum BDNF levels in patients with nicotine dependence.

Journal: Human psychopharmacology 20100401

Title: Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 3'-(substituted phenyl)epibatidine analogues. Nicotinic partial agonists.

Journal: Journal of natural products 20100326

Title: Varenicline and pheochromocytoma.

Journal: Annals of internal medicine 20100302

Title: Cost effectiveness of varenicline versus bupropion and unaided cessation for smoking cessation in a cohort of Finnish adult smokers.

Journal: Current medical research and opinion 20100301

Title: Modulation of ethanol consumption by genetic and pharmacological manipulation of nicotinic acetylcholine receptors in mice.

Journal: Psychopharmacology 20100301

Title: Varenicline effects on cocaine self administration and reinstatement behavior.

Journal: Behavioural pharmacology 20100301

Title: Quantitative assessment of exposure-response relationships for the efficacy and tolerability of varenicline for smoking cessation.

Journal: Clinical pharmacology and therapeutics 20100301

Title: Neuronal nicotinic acetylcholine receptors as pharmacotherapeutic targets for the treatment of alcohol use disorders.

Journal: CNS & neurological disorders drug targets 20100301

Title: Smoking cessation intervention: an evidence-based approach.

Journal: Postgraduate medicine 20100301

Title: Integrating smoking cessation into HIV care.

Journal: AIDS patient care and STDs 20100301

Title: Rapid and sustained response to a single dose of sertraline in a patient with newly emergent depression during varenicline-assisted smoking cessation.

Journal: CNS spectrums 20100301

Title: Effect of the alpha4beta2* nicotinic acetylcholine receptor partial agonist varenicline on dopamine release in beta2 knock-out mice with selective re-expression of the beta2 subunit in the ventral tegmental area.

Journal: Neuropharmacology 20100201

Title: The nicotinic acetylcholine receptor partial agonist varenicline and the treatment of drug dependence: a review.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20100201

Title: The alpha4beta2 nicotinic acetylcholine-receptor partial agonist varenicline inhibits both nicotine self-administration following repeated dosing and reinstatement of nicotine seeking in rats.

Journal: Psychopharmacology 20100201

Title: Current approaches to pharmacotherapy for smoking cessation.

Journal: Therapeutic advances in respiratory disease 20100201

Title: Improving the effectiveness of tobacco use cessation (TUC).

Journal: International dental journal 20100201

Title: Current treatment options in smoking cessation.

Journal: Hospital practice (1995) 20100201

Title: Varenicline and P50 auditory gating in medicated schizophrenic patients: a pilot study.

Journal: Psychiatry research 20100130

Title: Varenicline for smoking cessation in patients with coronary heart disease.

Journal: Circulation 20100119

Title: Efficacy and safety of varenicline for smoking cessation in patients with cardiovascular disease: a randomized trial.

Journal: Circulation 20100119

Title: Pharmacogenetics of smoking cessation therapy.

Journal: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 20100105

Title: Working memory deficits predict short-term smoking resumption following brief abstinence.

Journal: Drug and alcohol dependence 20100101

Title: [Tolerability profile of varenicline in current medical practice].

Journal: Presse medicale (Paris, France : 1983) 20100101

Title: Crossing borders: factors affecting differences in cost-effectiveness of smoking cessation interventions between European countries.

Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20100101

Title: The cost-effectiveness of an extended course (12+12 weeks) of varenicline compared with other available smoking cessation strategies in the United States: an extension and update to the BENESCO model.

Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20100101

Title: Varenicline: a pharmacoeconomic review of its use as an aid to smoking cessation.

Journal: PharmacoEconomics 20100101

Title: [Medications for smoking cessation. New advice concerning important neuropsychiatric effects].

Journal: Perspective infirmiere : revue officielle de l'Ordre des infirmieres et infirmiers du Quebec 20100101

Title: Non smoking for successful aging: therapeutic perspectives.

Journal: Current pharmaceutical design 20100101

Title: Varenicline for smokeless tobacco dependence.

Journal: Journal of postgraduate medicine 20100101

Title: [More or less smoked news].

Journal: Pneumologia (Bucharest, Romania) 20100101

Title: Stopping smokeless tobacco with varenicline: randomised double blind placebo controlled trial.

Journal: BMJ (Clinical research ed.) 20100101

Title: Prescription drugs associated with reports of violence towards others.

Journal: PloS one 20100101

Title: Smoking cessation in patients with chronic kidney disease.

Journal: CANNT journal = Journal ACITN 20100101

Title: Varenicline and suicide. Safety data from New Zealand.

Journal: BMJ (Clinical research ed.) 20091231

Title: Cost-effectiveness of varenicline compared with nicotine patches for smoking cessation--results from four European countries.

Journal: European journal of public health 20091201

Title: Sibutramine for weight gain attenuation during smoking cessation with varenicline: a pilot study.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20091201

Title: A retrospective poison center review of varenicline-exposed patients.

Journal: The Annals of pharmacotherapy 20091201

Title: Varenicline and antiretroviral therapy in patients with HIV.

Journal: Journal of acquired immune deficiency syndromes (1999) 20091201

Title: Varenicline and suicide. Risk of psychiatric side effects with varenicline.

Journal: BMJ (Clinical research ed.) 20091201

Title: Smoking cessation agents and suicide.

Journal: BMJ (Clinical research ed.) 20091105

Title: Varenicline attenuates some of the subjective and physiological effects of intravenous nicotine in humans.

Journal: Psychopharmacology 20091101

Title: What do we know about the role of pharmacotherapy for smoking cessation before or during pregnancy?

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20091101

Title: [Drug treatment of tobacco dependence].

Journal: Deutsche medizinische Wochenschrift (1946) 20091101

Title: Population pharmacokinetic analysis of varenicline in adult smokers.

Journal: British journal of clinical pharmacology 20091101

Title: Nicotine dependence and smoking cessation.

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20091101

Title: Varenicline-induced acute generalized exanthematous pustulosis.

Journal: Clinical and experimental dermatology 20091001

Title: Preclinical pharmacology of the alpha4beta2 nAChR partial agonist varenicline related to effects on reward, mood and cognition.

Journal: Biochemical pharmacology 20091001

Title: Smoking cessation: how to advise the patient.

Journal: Heart (British Cardiac Society) 20091001

Title: Acute generalized exanthematous pustulosis caused by varenicline.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20090901

Title: Acute hepatic injury associated with varenicline in a patient with underlying liver disease.

Journal: The Annals of pharmacotherapy 20090901

Title: Varenicline increases striatal dopamine D(2/3) receptor binding in rats.

Journal: Addiction biology 20090901

Title: Varenicline in prevention of relapse to smoking: effect of quit pattern on response to extended treatment.

Journal: Addiction (Abingdon, England) 20090901

Title: Lambert-Eaton myasthenic syndrome following varenicline (Chantix) use.

Journal: Muscle & nerve 20090901

Title: Varenicline in the management of smoking cessation: a single technology appraisal.

Journal: Health technology assessment (Winchester, England) 20090901

Title: Varenicline gets stronger warnings about psychiatric problems, vehicle crashes.

Journal: JAMA 20090826

Title: Safety of smoking cessation drugs.

Journal: The Medical letter on drugs and therapeutics 20090824

Title: Are nicotine replacement therapy, varenicline or bupropion options for pregnant mothers to quit smoking? Effects on the respiratory system of the offspring.

Journal: Therapeutic advances in respiratory disease 20090801

Title: Varenicline reduces alcohol self-administration in heavy-drinking smokers.

Journal: Biological psychiatry 20090715

Title: Varenicline: a novel pharmacotherapy for smoking cessation.

Journal: Drugs 20090709

Title: Varenicline augmentation in depressed smokers: an 8-week, open-label study.

Journal: The Journal of clinical psychiatry 20090701

Title: Tobacco dependence and withdrawal: science base, challenges and opportunities for pharmacotherapy.

Journal: Pharmacology & therapeutics 20090701

Title: Varenicline attenuates nicotine-enhanced brain-stimulation reward by activation of alpha4beta2 nicotinic receptors in rats.

Journal: Neuropharmacology 20090701

Title: Worsening psychosis induced by varenicline in a hospitalized psychiatric patient.

Journal: Pharmacotherapy 20090701

Title: Varenicline overdose in a teenager--a clinical pharmacology perspective.

Journal: Clinical toxicology (Philadelphia, Pa.) 20090701

Title: Varenicline-induced mixed mood and psychotic episode in a patient with Schizoaffective Disorder.

Journal: CNS spectrums 20090701

Title: Impact of symptoms experienced by varenicline users on tobacco treatment in a real world setting.

Journal: Journal of substance abuse treatment 20090601

Title: Does varenicline induce acute interstitial nephritis?

Journal: Mayo Clinic proceedings 20090601

Title: Varenicline and proximal myopathy.

Journal: The Medical journal of Australia 20090601

Title: Tobacco use among individuals with intellectual or developmental disabilities: a brief review.

Journal: Intellectual and developmental disabilities 20090601

Title: Subjective improvement in proprioception in 2 patients with atypical Friedreich ataxia treated with varenicline (Chantix).

Journal: Journal of clinical neuromuscular disease 20090601

Title: [Current and future medical drugs for smoking cessation].

Journal: Laryngo- rhino- otologie 20090601

Title: Cost-effectiveness of varenicline for smoking cessation.

Journal: Expert review of pharmacoeconomics & outcomes research 20090601

Title: Smoking-cessation therapy using varenicline: the cost-utility of an additional 12-week course of varenicline for the maintenance of smoking abstinence.

Journal: Journal of evaluation in clinical practice 20090601

Title: Varenicline reduced smoking behaviour in a mentally ill person.

Journal: Journal of psychopharmacology (Oxford, England) 20090501

Title: Persistent genital arousal disorder: a case report in a woman with lifelong PGAD where serendipitous administration of varenicline tartrate resulted in symptomatic improvement.

Journal: The journal of sexual medicine 20090501

Title: Mood, side-effects and smoking outcomes among persons with and without probable lifetime depression taking varenicline.

Journal: Journal of general internal medicine 20090501

Title: Cognitive and antismoking effects of varenicline in patients with schizophrenia or schizoaffective disorder.

Journal: Schizophrenia research 20090501

Title: Combination treatment with varenicline and nicotine replacement therapy.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20090501

Title: Safety and effectiveness of varenicline in a veteran population with a high prevalence of mental illness.

Journal: The Annals of pharmacotherapy 20090501

Title: Hallucinations in the context of varenicline withdrawal.

Journal: The American journal of psychiatry 20090501

Title: Reduced affective symptoms during tobacco dependence treatment with varenicline.

Journal: Addiction (Abingdon, England) 20090501

Title: Do the 10 UK suicides among those taking the smoking cessation drug varenicline suggest a causal link?

Journal: Addiction (Abingdon, England) 20090501

Title: Treatment of comorbid tobacco use in people with serious mental illness.

Journal: Journal of psychiatry & neuroscience : JPN 20090501

Title: Chantix-induced mental status changes in a young healthy female.

Journal: South Dakota medicine : the journal of the South Dakota State Medical Association 20090501

Title: Findings on alcohol dependence point to promising avenues for targeted therapies.

Journal: JAMA 20090422

Title: The relevance and treatment of cue-induced cravings in tobacco dependence.

Journal: Journal of substance abuse treatment 20090401

Title: The smoking cessation medication varenicline attenuates alcohol and nicotine interactions in the rat mesolimbic dopamine system.

Journal: The Journal of pharmacology and experimental therapeutics 20090401

Title: Smoking in pregnancy and lactation: a review of risks and cessation strategies.

Journal: European journal of clinical pharmacology 20090401

Title: Varenicline for smoking cessation: a placebo-controlled, randomized study.

Journal: Respirology (Carlton, Vic.) 20090401

Title: Varenicline overdose in a teenager.

Journal: Clinical toxicology (Philadelphia, Pa.) 20090401

Title: The pharmacokinetic and tolerability profile of varenicline in healthy Chinese volunteers.

Journal: International journal of clinical pharmacology and therapeutics 20090401

Title: Two recent updates for psychiatric conditions.

Journal: Journal of child and adolescent psychopharmacology 20090401

Title: Update on smoking cessation therapies.

Journal: Advances in therapy 20090401

Title: Real world study to evaluate the effectiveness of varenicline and cognitive-behavioural interventions for smoking cessation.

Journal: International journal of environmental research and public health 20090401

Title: Smoking cessation: aspects of prevention and therapy. The activity of the Smoking Cessation Center of Parma-Italy.

Journal: Acta bio-medica : Atenei Parmensis 20090401

Title: Studies linking smoking-cessation drug with suicide risk spark concerns.

Journal: JAMA 20090311

Title: Varenicline has antidepressant-like activity in the forced swim test and augments sertraline's effect.

Journal: European journal of pharmacology 20090301

Title: Smoking cessation with varenicline: a suicidal fatality.

Journal: Journal of analytical toxicology 20090301

Title: Varenicline and bupropion sustained-release combination therapy for smoking cessation.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20090301

Title: Emerging drugs for the treatment of tobacco dependence.

Journal: Expert opinion on emerging drugs 20090301

Title: Varenicline: a first-line treatment option for smoking cessation.

Journal: Clinical therapeutics 20090301

Title: Antismoking drug still recommended to Canadians despite side effects and US advisory.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20090217

Title: Varenicline for tobacco dependence.

Journal: The New England journal of medicine 20090212

Title: Varenicline for tobacco dependence.

Journal: The New England journal of medicine 20090212

Title: A 51-year-old woman with bipolar disorder who wants to quit smoking.

Journal: JAMA 20090204

Title: Treatment of imbalance with varenicline Chantix(R): report of a patient with fragile X tremor/ataxia syndrome.

Journal: Acta neurologica Scandinavica 20090201

Title: An algorithm for tailoring pharmacotherapy for smoking cessation: results from a Delphi panel of international experts.

Journal: Tobacco control 20090201

Title: Interventions for preventing weight gain after smoking cessation.

Journal: The Cochrane database of systematic reviews 20090121

Title: Varenicline improves mood and cognition during smoking abstinence.

Journal: Biological psychiatry 20090115

Title: Budgetary impact of varenicline in smoking cessation in the United Kingdom.

Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20090101

Title: Effects of the nicotinic receptor partial agonists varenicline and cytisine on the discriminative stimulus effects of nicotine in rats.

Journal: Pharmacology, biochemistry, and behavior 20090101

Title: Pharmacology of nicotine: addiction, smoking-induced disease, and therapeutics.

Journal: Annual review of pharmacology and toxicology 20090101

Title: [Modern medical support for smoking cessation].

Journal: Der Internist 20090101

Title: Update in new medications for primary care.

Journal: Journal of general internal medicine 20090101

Title: Targeting reward-relevant nicotinic receptors in the discovery of novel pharmacotherapeutic agents to treat tobacco dependence.

Journal: Nebraska Symposium on Motivation. Nebraska Symposium on Motivation 20090101

Title: New findings on nicotine addiction and treatment.

Journal: Nebraska Symposium on Motivation. Nebraska Symposium on Motivation 20090101

Title: Quitting smoking without a psychotic break: the potential link between nicotinic acetylcholine receptor partial agonists and neuropsychiatric adverse events.

Journal: Clinical nurse specialist CNS 20090101

Title: Do implementation issues influence the effectiveness of medications? The case of nicotine replacement therapy and bupropion in UK Stop Smoking Services.

Journal: BMC public health 20090101

Title: [Varenicline - pharmacological therapy of tobacco dependence].

Journal: Wiener medizinische Wochenschrift (1946) 20090101

Title: A preliminary benefit-risk assessment of varenicline in smoking cessation.

Journal: Drug safety 20090101

Title: Pharmacokinetics, safety, and tolerability of varenicline in healthy adolescent smokers: a multicenter, randomized, double-blind, placebo-controlled, parallel-group study.

Journal: Clinical therapeutics 20090101

Title: Cost-utility analysis of varenicline, an oral smoking-cessation drug, in Japan.

Journal: PharmacoEconomics 20090101

Title: Successful smoking cessation and improvement of negative symptoms with varenicline in a stable schizophrenia patient.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20090101

Title: Smoking and chronic obstructive pulmonary disease (COPD). Parallel epidemics of the 21 century.

Journal: International journal of environmental research and public health 20090101

Title: Safety and drug utilization profile of varenicline as used in general practice in England: interim results from a prescription-event monitoring study.

Journal: Drug safety 20090101

Title: Varenicline-induced mania in a bipolar patient.

Journal: Clinical neuropharmacology 20090101

Title: [Cardiac arrest with varenicline: a case report].

Journal: Therapie 20090101

Title: Treating tobacco dependence in a medical setting.

Journal: CA: a cancer journal for clinicians 20090101

Title: Cost effectiveness of varenicline in Belgium, compared with bupropion, nicotine replacement therapy, brief counselling and unaided smoking cessation: a BENESCO Markov cost-effectiveness analysis.

Journal: Clinical drug investigation 20090101

Title: Varenicline and suicidal behaviour: a cohort study based on data from the General Practice Research Database.

Journal: BMJ (Clinical research ed.) 20090101

Title: [A multidisciplinary approach of nicotine addiction--the new face of the tabaccology conference. Iaşi, June 25-27, 2009].

Journal: Pneumologia (Bucharest, Romania) 20090101

Title: Practical implementation of varenicline as an aid to smoking cessation in clinical practice.

Journal: Pneumologia (Bucharest, Romania) 20090101

Title: Regulation of smoking cessation drugs by the Food and Drug Administration.

Journal: Food and drug law journal 20090101

Title: Clinical utility of varenicline for smokers with medical and psychiatric comorbidity.

Journal: International journal of chronic obstructive pulmonary disease 20090101

Title: Varenicline: for smoking cessation.

Journal: Kathmandu University medical journal (KUMJ) 20090101

Title: Evaluation of cost-utility of varenicline compared with existing smoking cessation therapies in South Korea.

Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20090101

Title: Cost-effectiveness of pharmacogenetic testing to tailor smoking-cessation treatment.

Journal: The pharmacogenomics journal 20081201

Title: Effect of varenicline on the acute and repeated locomotor responses to nicotine in rats.

Journal: Synapse (New York, N.Y.) 20081201

Title: Varenicline-associated acute renal failure.

Journal: The Annals of pharmacotherapy 20081201

Title: Possible varenicline-induced paranoia and irritability in a patient with major depressive disorder, borderline personality disorder, and methamphetamine abuse in remission.

Journal: Journal of clinical psychopharmacology 20081201

Title: [Drug treatment for smoking and marijuana abuse].

Journal: Revue des maladies respiratoires 20081201

Title: [Specific program for smoking cessation: thus your patients become nonsmokers].

Journal: MMW Fortschritte der Medizin 20081113

Title: Varenicline for tobacco dependence.

Journal: The New England journal of medicine 20081106

Title: Lack of a pharmacokinetic interaction between a new smoking cessation therapy, varenicline, and digoxin in adult smokers.

Journal: European journal of clinical pharmacology 20081101

Title: The influence of acute varenicline administration on smoking and eating behavior in humans.

Journal: Pharmacology, biochemistry, and behavior 20081101

Title: Multimodal techniques for smoking cessation: a review of their efficacy and utilisation and clinical practice guidelines.

Journal: International journal of clinical practice 20081101

Title: Smoking cessation in pregnancy.

Journal: Expert opinion on drug safety 20081101

Title: Smoking cessation: new ways to quit.

Journal: Harvard men's health watch 20081101

Title: Suicidal ideation and varenicline: a possible case of mistaken adverse drug reaction?

Journal: The Journal of clinical psychiatry 20081101

Title: Varenicline and smokers with mental illnesses.

Journal: Lancet (London, England) 20081004

Title: Nicotinic receptor partial agonists as novel compounds for the treatment of smoking cessation.

Journal: Expert opinion on investigational drugs 20081001

Title: Varenicline ameliorates nicotine withdrawal-induced learning deficits in C57BL/6 mice.

Journal: Behavioral neuroscience 20081001

Title: Pharmacotherapy for smoking cessation.

Journal: Therapeutic advances in respiratory disease 20081001

Title: [Varenicline for smoking cessation].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20080911

Title: Neuropsychiatric disturbance after initiation of varenicline in a patient with a history of alcohol abuse and major depression.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080901

Title: Drugs for tobacco dependence.

Journal: Treatment guidelines from the Medical Letter 20080901

Title: The risk-benefit balance of varenicline for smoking cessation.

Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20080901

Title: Varenicline and suicidality: a new era in medication safety surveillance.

Journal: Expert opinion on drug safety 20080901

Title: First in class.

Journal: Scientific American 20080901

Title: Smoking cessation: the psychiatrist's role.

Journal: Journal of psychiatry & neuroscience : JPN 20080901

Title: Varenicline versus transdermal nicotine patch for smoking cessation: results from a randomised open-label trial.

Journal: Thorax 20080801

Title: Varenicline efficacy and tolerability in a subject with schizophrenia.

Journal: Schizophrenia research 20080801

Title: The place of varenicline in smoking cessation treatment.

Journal: Thorax 20080801

Title: Pre-cessation varenicline treatment vs post-cessation NRT: an uneven playing field.

Journal: Thorax 20080801

Title: Clinically significant outcomes in smoking cessation.

Journal: Thorax 20080801

Title: Tobacco smoking cessation management: integrating varenicline in current practice.

Journal: Vascular health and risk management 20080801

Title: Nicotine receptor partial agonists for smoking cessation.

Journal: The Cochrane database of systematic reviews 20080716

Title: Pharmacotherapies for smoking cessation: a meta-analysis of randomized controlled trials.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20080715

Title: Varenicline (Chantix) warnings: risk versus benefit.

Journal: The Medical letter on drugs and therapeutics 20080714

Title: Varenicline ameliorates ethanol-induced deficits in learning in C57BL/6 mice.

Journal: Neurobiology of learning and memory 20080701

Title: The efficacy and safety of varenicline for smoking cessation using a flexible dosing strategy in adult smokers: a randomized controlled trial.

Journal: Current medical research and opinion 20080701

Title: Diffuse exanthema in a patient receiving varenicline.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080701

Title: Clinical inquiries. What are the most effective ways you can help patients stop smoking?

Journal: The Journal of family practice 20080701

Title: [Champix not suitable for elderly with depression].

Journal: Lakartidningen 20080701

Title: [Cost effectiveness analysis of varenicline (Champix) for the treatment of smoking in Spain].

Journal: Anales de medicina interna (Madrid, Spain : 1984) 20080701

Title: Updated US smoking cessation guideline advises counseling, combining therapies.

Journal: JAMA 20080618

Title: Smoking cessation in pregnancy: why, how, and what next..

Journal: Clinical obstetrics and gynecology 20080601

Title: Pharmacological effects of nicotine on norepinephrine metabolism in rat brown adipose tissue: relevance to nicotinic therapies for smoking cessation.

Journal: Toxicologic pathology 20080601

Title: Exacerbation of recurrent depression as a result of treatment with varenicline.

Journal: The American journal of psychiatry 20080601

Title: Varenicline-induced mixed mood and psychotic episode in a patient with a past history of depression.

Journal: CNS spectrums 20080601

Title: Which drug to be used in smoking cessation?

Journal: Polskie Archiwum Medycyny Wewnetrznej 20080601

Title: Varenicline treatment for smokers with schizophrenia: a case series.

Journal: The Journal of clinical psychiatry 20080601

Title: Smoking cessation therapy with varenicline.

Journal: International journal of chronic obstructive pulmonary disease 20080601

Title: Varenicline as compared to bupropion in smoking-cessation therapy--cost-utility results for Sweden 2003.

Journal: Respiratory medicine 20080501

Title: Varenicline may trigger severe hypoglycaemia in Type 1 diabetes.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20080501

Title: Empowering dental hygienists: tobacco cessation resources.

Journal: International journal of dental hygiene 20080501

Title: Varenicline for smoking cessation.

Journal: Drug and therapeutics bulletin 20080501

Title: [The ABC of smoking cessation].

Journal: Medizinische Monatsschrift fur Pharmazeuten 20080501

Title: New kid on the block: Chantix for smoking cessation.

Journal: Texas dental journal 20080501

Title: Stat bite: Medicaid coverage of tobacco-dependence treatments.

Journal: Journal of the National Cancer Institute 20080402

Title: N-methylation and N-formylation of a secondary amine drug (varenicline) in an osmotic tablet.

Journal: Journal of pharmaceutical sciences 20080401

Title: Effect of human renal cationic transporter inhibition on the pharmacokinetics of varenicline, a new therapy for smoking cessation: an in vitro-in vivo study.

Journal: Clinical pharmacology and therapeutics 20080401

Title: Effect of varenicline and bupropion SR on craving, nicotine withdrawal symptoms, and rewarding effects of smoking during a quit attempt.

Journal: Psychopharmacology 20080401

Title: Human abuse liability of the smoking cessation drug varenicline in smokers and nonsmokers.

Journal: Clinical pharmacology and therapeutics 20080401

Title: Clinical pharmacology of nicotine: implications for understanding, preventing, and treating tobacco addiction.

Journal: Clinical pharmacology and therapeutics 20080401

Title: Breaking away from a narrow prescribing protocol for medicinal nicotine.

Journal: Addiction (Abingdon, England) 20080401

Title: Efficacy and safety of varenicline for smoking cessation.

Journal: The American journal of medicine 20080401

Title: Drug addiction: a critical problem calling for novel solutions.

Journal: Clinical pharmacology and therapeutics 20080401

Title: Smoking cessation 2008.

Journal: IDrugs : the investigational drugs journal 20080401

Title: What's new in clinical pharmacology and therapeutics.

Journal: WMJ : official publication of the State Medical Society of Wisconsin 20080401

Title: FDA warns of adverse events linked to smoking cessation drug and antiepileptics.

Journal: JAMA 20080312

Title: Comment and reply: A double-blind study evaluating the long-term safety of varenicline for smoking cessation.

Journal: Current medical research and opinion 20080201

Title: Hypomania with agitation associated with varenicline use in bipolar II disorder.

Journal: The Annals of pharmacotherapy 20080201

Title: Smoking cessation and lung cancer: oncology nurses can make a difference.

Journal: Seminars in oncology nursing 20080201

Title: Varenicline: a new pharmaceutical approach to smoking cessation.

Journal: Nursing for women's health 20080201

Title: Cost-effectiveness of varenicline compared with bupropion, NRT, and nortriptyline for smoking cessation in the Netherlands.

Journal: Current medical research and opinion 20080101

Title: Varenicline in the routine treatment of tobacco dependence: a pre-post comparison with nicotine replacement therapy and an evaluation in those with mental illness.

Journal: Addiction (Abingdon, England) 20080101

Title: An update on therapeutics for tobacco dependence.

Journal: Expert opinion on pharmacotherapy 20080101

Title: Smoking cessation--what works?

Journal: Australian family physician 20080101

Title: Varenicline versus bupropion SR or placebo for smoking cessation: a pooled analysis.

Journal: American journal of health behavior 20080101

Title: Cost-utility analysis of varenicline versus existing smoking cessation strategies using the BENESCO Simulation model: application to a population of US adult smokers.

Journal: PharmacoEconomics 20080101

Title: Chantix.

Journal: Plastic surgical nursing : official journal of the American Society of Plastic and Reconstructive Surgical Nurses 20080101

Title: Varenicline and its role in smoking cessation.

Journal: Preventive cardiology 20080101

Title: Smoking cessation therapy considerations for patients with chronic kidney disease.

Journal: Nephrology nursing journal : journal of the American Nephrology Nurses' Association 20080101

Title: Systematic review and meta-analysis of combination therapy for smoking cessation.

Journal: Journal of the American Pharmacists Association : JAPhA 20080101

Title: [Not smoking, essential for healthy lungs].

Journal: Pharmazie in unserer Zeit 20080101

Title: Treatment of ataxia and imbalance with varenicline (chantix): report of 2 patients with spinocerebellar ataxia (types 3 and 14).

Journal: Clinical neuropharmacology 20080101

Title: Smoking cessation in cardiovascular patients.

Journal: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20080101

Title: [Pharmacotherapy of smoking cessation with application of nicotine and nicotine free drugs].

Journal: Przeglad lekarski 20080101

Title: Varenicline and adult ADHD.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20080101

Title: Varenicline, appetite, and weight reduction.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20080101

Title: A reader responds to 'Seven pharmacotherapies do promote smoking abstinence at 6 and 12 months'.

Journal: Medscape journal of medicine 20080101

Title: A longer course of varenicline therapy improves smoking cessation rates.

Journal: Preventive cardiology 20080101

Title: Which is the best primary medication for long-term smoking cessation--nicotine replacement therapy, bupropion or varenicline?

Journal: Expert opinion on pharmacotherapy 20071201

Title: Treatment of tobacco dependence: integrating recent progress into practice.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20071120

Title: [Varenicline--a new drug for smoking cessation].

Journal: Ugeskrift for laeger 20071119

Title: [New drugs; varenicline].

Journal: Nederlands tijdschrift voor geneeskunde 20071110

Title: Lack of pharmacokinetic and pharmacodynamic interactions between a smoking cessation therapy, varenicline, and warfarin: an in vivo and in vitro study.

Journal: Journal of clinical pharmacology 20071101

Title: Smoking cessation: an overview of treatment options with a focus on varenicline.

Journal: Pharmacotherapy 20071101

Title: Breaking the ties of nicotine dependence.

Journal: The Nurse practitioner 20071101

Title: Interference with smoking-cessation effects of varenicline after administration of immediate-release amphetamine-dextroamphetamine.

Journal: Pharmacotherapy 20071001

Title: Smoking cessation: tactics that make a big difference.

Journal: The Journal of family practice 20071001

Title: A new medication for the worst addiction.

Journal: Current psychiatry reports 20071001

Title: A second varenicline trial.

Journal: Current psychiatry reports 20071001

Title: Varenicline as maintenance therapy.

Journal: Current psychiatry reports 20071001

Title: Treating tobacco dependence in women.

Journal: Journal of women's health (2002) 20071001

Title: The truth about smoking cessation.

Journal: The Johns Hopkins medical letter health after 50 20071001

Title: The cost effectiveness of varenicline for smoking cessation.

Journal: Managed care interface 20071001

Title: A call to action: new treatment options provide even more reasons to intervene in tobacco dependence.

Journal: Nature clinical practice. Cardiovascular medicine 20070901

Title: [Varenicline].

Journal: Revue de l'infirmiere 20070901

Title: An evaluation of the OECD 308 water/sediment systems for investigating the biodegradation of pharmaceuticals.

Journal: Environmental science & technology 20070815

Title: Varenicline-induced manic episode in a patient with bipolar disorder.

Journal: The American journal of psychiatry 20070801

Title: Exacerbation of schizophrenia by varenicline.

Journal: The American journal of psychiatry 20070801

Title: Varenicline: progress in smoking cessation treatment.

Journal: Expert opinion on pharmacotherapy 20070801

Title: Optimizing on smoke free legislation making the most of the opportunity.

Journal: British journal of community nursing 20070801

Title: Smoking cessation: lessons learned from clinical trial evidence.

Journal: Current opinion in cardiology 20070701

Title: Rationale, pharmacology and clinical efficacy of partial agonists of alpha4beta2 nACh receptors for smoking cessation.

Journal: Trends in pharmacological sciences 20070701

Title: Varenicline: the newest agent for smoking cessation.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070701

Title: The pharmacist's role in tobacco cessation: overview and introduction to the series.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070701

Title: New non-nicotine drug to help smoking cessation efforts.

Journal: Nursing times 20070601

Title: Why choose varenicline (chantix) for smoking cessation treatment?

Journal: Issues in mental health nursing 20070601

Title: Smoking cessation update.

Journal: South Dakota medicine : the journal of the South Dakota State Medical Association 20070601

Title: [New smoking cessation preparations unsuitable in mental disorders].

Journal: Lakartidningen 20070601

Title: How well does the new drug varenicline work for people who want to stop smoking?

Journal: The Harvard mental health letter 20070601

Title: A randomized, placebo-controlled trial of varenicline, a selective alpha4beta2 nicotinic acetylcholine receptor partial agonist, as a new therapy for smoking cessation in Asian smokers.

Journal: Clinical therapeutics 20070601

Title: Efficacy and tolerability of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, in a 12-week, randomized, placebo-controlled, dose-response study with 40-week follow-up for smoking cessation in Japanese smokers.

Journal: Clinical therapeutics 20070601

Title: Confirmatory factor analyses and reliability of the modified cigarette evaluation questionnaire.

Journal: Addictive behaviors 20070501

Title: Comment: Oral varenicline for smoking cessation.

Journal: The Annals of pharmacotherapy 20070401

Title: A double-blind study evaluating the long-term safety of varenicline for smoking cessation.

Journal: Current medical research and opinion 20070401

Title: An employer-based cost-benefit analysis of a novel pharmacotherapy agent for smoking cessation.

Journal: Journal of occupational and environmental medicine 20070401

Title: Pharmacological profile of the alpha4beta2 nicotinic acetylcholine receptor partial agonist varenicline, an effective smoking cessation aid.

Journal: Neuropharmacology 20070301

Title: [The path from cigarettes--with support it works better].

Journal: Medizinische Monatsschrift fur Pharmazeuten 20070301

Title: [Varenicline--a new drug for smoking cessation].

Journal: Medizinische Monatsschrift fur Pharmazeuten 20070301

Title: The most addictive drug, the most deadly substance: smoking cessation tactics for the busy clinician.

Journal: Primary care 20070301

Title: [Giving up smoking is crucial for COPD patients].

Journal: MMW Fortschritte der Medizin 20070222

Title: Ligands selective for alpha4beta2 but not alpha3beta4 or alpha7 nicotinic receptors generalise to the nicotine discriminative stimulus in the rat.

Journal: Psychopharmacology 20070201

Title: Impact of pharmacometric reviews on new drug approval and labeling decisions--a survey of 31 new drug applications submitted between 2005 and 2006.

Journal: Clinical pharmacology and therapeutics 20070201

Title: Drug approvals.

Journal: The Nurse practitioner 20070201

Title: Varenicline for smoking cessation.

Journal: Expert review of neurotherapeutics 20070201

Title: Varenicline: new treatment with efficacy in smoking cessation.

Journal: Drugs of today (Barcelona, Spain : 1998) 20070201

Title: [Drug of the month. Varenicline (Champix)].

Journal: Revue medicale de Liege 20070201

Title: [Champix has become a registered drug].

Journal: Orvosi hetilap 20070128

Title: Nicotine receptor partial agonists for smoking cessation.

Journal: The Cochrane database of systematic reviews 20070124

Title: Mechanism of varenicline (clinical ramifications): electron transfer and oxidative stress.

Journal: Medical hypotheses 20070101

Title: Oral varenicline for smoking cessation.

Journal: The Annals of pharmacotherapy 20070101

Title: Non-nicotinic therapies for smoking cessation.

Journal: Annual review of pharmacology and toxicology 20070101

Title: A clinical imperative: assisting patients who smoke to reduce their risk of cardiovascular disease.

Journal: Preventive cardiology 20070101

Title: Smoking cessation pharmacotherapy--nicotine and non-nicotine preparations.

Journal: Preventive cardiology 20070101

Title: Maximizing smoking cessation in clinical practice: pharmacologic and behavioral interventions.

Journal: Preventive cardiology 20070101

Title: [Tobacco use prevention and cessation in the dental practice].

Journal: Schweizer Monatsschrift fur Zahnmedizin = Revue mensuelle suisse d'odonto-stomatologie = Rivista mensile svizzera di odontologia e stomatologia 20070101

Title: Varenicline: a selective alpha4beta2 nicotinic acetylcholine receptor partial agonist approved for smoking cessation.

Journal: Cardiology in review 20070101

Title: [Varenicline (Champix)].

Journal: Journal de pharmacie de Belgique 20070101

Title: Alcohol history and smoking cessation in nicotine replacement therapy, bupropion sustained release and varenicline trials: a review.

Journal: Alcohol and alcoholism (Oxford, Oxfordshire) 20070101

Title: Kicking butts: smoking cessation update.

Journal: Missouri medicine 20070101

Title: [Varenicline: an aid to smoking cessation therapy].

Journal: Revue medicale de Bruxelles 20070101

Title: [Varenicline--a new chance for smokers?].

Journal: Przeglad lekarski 20070101

Title: Efficacy of varenicline for smoking cessation.

Journal: JAMA 20061206

Title: Multiple-dose pharmacokinetics of the selective nicotinic receptor partial agonist, varenicline, in healthy smokers.

Journal: Journal of clinical pharmacology 20061201

Title: Trials that matter: varenicline: a designer drug to help smokers quit.

Journal: Annals of internal medicine 20061121

Title: Pharmacokinetics, safety, and tolerability after single and multiple oral doses of varenicline in elderly smokers.

Journal: Journal of clinical pharmacology 20061101

Title: New prescription drug available to help smokers stop.

Journal: Mayo Clinic health letter (English ed.) 20061001

Title: Varenicline is a partial agonist at alpha4beta2 and a full agonist at alpha7 neuronal nicotinic receptors.

Journal: Molecular pharmacology 20060901

Title: Single-dose pharmacokinetics of varenicline, a selective nicotinic receptor partial agonist, in healthy smokers and nonsmokers.

Journal: Journal of clinical pharmacology 20060901

Title: New weapon to curb smoking: no more excuses to delay treatment.

Journal: Archives of internal medicine 20060801

Title: Smoking cessation with varenicline, a selective alpha4beta2 nicotinic receptor partial agonist: results from a 7-week, randomized, placebo- and bupropion-controlled trial with 1-year follow-up.

Journal: Archives of internal medicine 20060801

Title: Efficacy and safety of the novel selective nicotinic acetylcholine receptor partial agonist, varenicline, for smoking cessation.

Journal: Archives of internal medicine 20060801

Title: Varenicline (Chantix) for tobacco dependence.

Journal: The Medical letter on drugs and therapeutics 20060801

Title: Varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs sustained-release bupropion and placebo for smoking cessation: a randomized controlled trial.

Journal: JAMA 20060705

Title: Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled trial.

Journal: JAMA 20060705

Title: Effect of maintenance therapy with varenicline on smoking cessation: a randomized controlled trial.

Journal: JAMA 20060705

Title: Varenicline for smoking cessation: definite promise, but no panacea.

Journal: JAMA 20060705

Title: Varenicline.

Journal: Nature reviews. Drug discovery 20060701

Title: The neurobiological basis for partial agonist treatment of nicotine dependence.

Journal: International journal of clinical practice 20060501

Title: The neurobiological basis for partial agonist treatment of nicotine dependence: varenicline.

Journal: International journal of clinical practice 20060501

Title: Molecule of the Month. Varenicline tartrate.

Journal: Drug news & perspectives 20060401

Title: Pharmacologic interventions for smoking cessation.

Journal: Critical care nursing clinics of North America 20060301

Title: FDA speeds smoking cessation drug review.

Journal: JAMA 20060208

Title: Metabolism and disposition of varenicline, a selective alpha4beta2 acetylcholine receptor partial agonist, in vivo and in vitro.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060101

Title: New drugs: varenicline tartrate, insulin glulisine, and insulin detemir.

Journal: Journal of the American Pharmacists Association : JAPhA 20060101

Title: Varenicline: a review of its use as an aid to smoking cessation therapy.

Journal: CNS drugs 20060101

Title: Effectiveness of smoking cessation therapies: a systematic review and meta-analysis.

Journal: BMC public health 20060101

Title: [New tobacco dependence drug: Varenicline, partial agonist of alpha4beta2 acetylcholine-nicotine receptors].

Journal: Casopis lekaru ceskych 20060101

Title: The FDA approves new drug for smoking cessation.

Journal: FDA consumer 20060101

Title: Smoking cessation efficacy and safety of varenicline, an alpha4beta2 nicotinic receptor partial agonist.

Journal: The Journal of cardiovascular nursing 20060101

Title: Varenicline (CHANTIX): a stop-smoking pill.

Journal: ORL-head and neck nursing : official journal of the Society of Otorhinolaryngology and Head-Neck Nurses 20060101

Title: [Medication for ending tobacco dependency. Current state].

Journal: Atencion primaria 20050630

Title: Varenicline: an alpha4beta2 nicotinic receptor partial agonist for smoking cessation.

Journal: Journal of medicinal chemistry 20050519

Title: Revealing the multidimensional framework of the Minnesota nicotine withdrawal scale.

Journal: Current medical research and opinion 20050501

Title: Krebs P, Sherman SE. Review: Varenicline for tobacco cessation does not increase CV serious adverse events. Ann Intern Med. 2012 Aug 21;157(4):JC2-2.

Title: Kikkawa, H.; Maruyama, N.; Fujimoto, Y.; Hasunuma, T. Single- and multiple-dose pharmacokinetics of the selective nicotinic receptor partial agonist, varenicline, in healthy Japanese adult smokers. Journal of Clinical Pharmacology (2011), 51(4), 527-537.

Title: Pachas GN, Cather C, Pratt SA et al. Varenicline for Smoking Cessation in Schizophrenia: Safety and Effectiveness in a 12-Week, Open-Label Trial. J Dual Diagn. 2012;8(2):117-125.

Title: Bordia T, Hrachova M, Chin M et al. Varenicline Is a Potent Partial Agonist at α6β2* Nicotinic Acetylcholine Receptors in Rat and Monkey Striatum. J Pharmacol Exp Ther. 2012 Aug;342(2):327-34.

Title: Varenicline

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Tags:375815-87-5 Molecular Formula|375815-87-5 MDL|375815-87-5 SMILES|375815-87-5 Varenicline tartrate