[1]EuropeanJournalofOrganicChemistry,2018,vol.2018,p.1821-1832
[2]TetrahedronLetters,2005,vol.46,p.5005-5007
[1]TetrahedronLetters,2005,vol.46,p.5005-5007
[2]OrganicLetters,2018,vol.20,p.4959-4963
[1]TetrahedronLetters,2005,vol.46,p.5005-5007
[2]OrganicLetters,2018,vol.20,p.4959-4963
[1]TetrahedronLetters,2005,vol.46,p.5005-5007
[2]TetrahedronLetters,2005,vol.46,p.5005-5007
[1]TetrahedronLetters,2005,vol.46,p.5005-5007
Title: Prenylated phloroglucinols from Hypericum scruglii, an endemic species of Sardinia (Italy), as new dual HIV-1 inhibitors effective on HIV-1 replication.
Journal: PloS one 20180101
Title: Highly specific blockade of CCR5 inhibits leukocyte trafficking and reduces mucosal inflammation in murine colitis.
Journal: Scientific reports 20160101
Title: Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis.
Journal: Chemical research in toxicology 20150518
Title: International Union of Basic and Clinical Pharmacology. XC. multisite pharmacology: recommendations for the nomenclature of receptor allosterism and allosteric ligands.
Journal: Pharmacological reviews 20141001
Title: Synergistic activity profile of carbosilane dendrimer G2-STE16 in combination with other dendrimers and antiretrovirals as topical anti-HIV-1 microbicide.
Journal: Nanomedicine : nanotechnology, biology, and medicine 20140401
Title: Preparation and activities of macromolecule conjugates of the CCR5 antagonist Maraviroc.
Journal: ACS medicinal chemistry letters 20140213
Title: Design, synthesis and biological evaluation of novel piperazine derivatives as CCR5 antagonists.
Journal: PloS one 20130101
Title: Mutations in variable domains of the HIV-1 envelope gene can have a significant impact on maraviroc and vicriviroc resistance.
Journal: AIDS research and therapy 20130101
Title: Monitoring the emergence of resistance mutations in patients infected with HIV-1 under salvage therapy with raltegravir in Rio de Janeiro, Brazil: a follow-up study.
Journal: Journal of medical virology 20121201
Title: Chemokine receptor antagonists.
Journal: Journal of medicinal chemistry 20121126
Title: Pharmacokinetic interaction between maraviroc and etravirine in HIV-infected patients receiving regimens containing both drugs and no ritonavir-boosted protease inhibitor.
Journal: The Journal of antimicrobial chemotherapy 20121101
Title: Next-generation oral preexposure prophylaxis: beyond tenofovir.
Journal: Current opinion in HIV and AIDS 20121101
Title: Population-based sequencing of the V3-loop can predict the virological response to maraviroc in treatment-naive patients of the MERIT trial.
Journal: Journal of acquired immune deficiency syndromes (1999) 20121101
Title: Immune recovery and T cell subset analysis during effective treatment with maraviroc.
Journal: The Journal of antimicrobial chemotherapy 20121001
Title: Antiretroviral neurotoxicity.
Journal: Journal of neurovirology 20121001
Title: Anti-retroviral drugs do not facilitate hepatitis C virus (HCV) infection in vitro.
Journal: Antiviral research 20121001
Title: Long-term glucose tolerance in highly experienced HIV-infected patients receiving nucleoside analogue-sparing regimens.
Journal: AIDS (London, England) 20120910
Title: Allosteric modulators of rhodopsin-like G protein-coupled receptors: opportunities in drug development.
Journal: Pharmacology & therapeutics 20120901
Title: Patients on a combined antiretroviral therapy after maraviroc clinical test show no immunovirological impairment.
Journal: Antiviral research 20120901
Title: HIV-1 CRF01_AE coreceptor usage prediction using kernel methods based logistic model trees.
Journal: Computers in biology and medicine 20120901
Title: Clinical studies with chemokine receptor-5 (CCR5)-inhibitors.
Journal: Current opinion in HIV and AIDS 20120901
Title: HIV population genotypic tropism testing and its clinical significance.
Journal: Current opinion in HIV and AIDS 20120901
Title: Phenotyping methods for determining HIV tropism and applications in clinical settings.
Journal: Current opinion in HIV and AIDS 20120901
Title: A pilot trial of adding maraviroc to suppressive antiretroviral therapy for suboptimal CD4⁺ T-cell recovery despite sustained virologic suppression: ACTG A5256.
Journal: The Journal of infectious diseases 20120815
Title: CCR5 antagonist blocks metastasis of basal breast cancer cells.
Journal: Cancer research 20120801
Title: The lowest X4 Geno2Pheno false-positive rate is associated with greater CD4 depletion in HIV-1 infected patients.
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20120801
Title: From in vitro EC₅₀ to in vivo dose-response for antiretrovirals using an HIV disease model. Part I: a framework.
Journal: Journal of pharmacokinetics and pharmacodynamics 20120801
Title: Chemokine receptor blockade in graft-versus-host disease.
Journal: The Lancet. Oncology 20120801
Title: New nitrogen containing substituents at the indole-2-carboxamide yield high potent and broad spectrum indolylarylsulfone HIV-1 non-nucleoside reverse transcriptase inhibitors.
Journal: Journal of medicinal chemistry 20120726
Title: Blockade of lymphocyte chemotaxis in visceral graft-versus-host disease.
Journal: The New England journal of medicine 20120712
Title: Virological failure at one year in triple-class experienced patients switching to raltegravir-based regimens is not predicted by baseline factors.
Journal: International journal of STD & AIDS 20120701
Title: V3 determinants of HIV-1 escape from the CCR5 inhibitors Maraviroc and Vicriviroc.
Journal: Virology 20120605
Title: Impact of triplicate testing on HIV genotypic tropism prediction in routine clinical practice.
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20120601
Title: Evolution of proviral DNA HIV-1 tropism under selective pressure of maraviroc-based therapy.
Journal: The Journal of antimicrobial chemotherapy 20120601
Title: Amino acid derivatives of the (-) enantiomer of gossypol are effective fusion inhibitors of human immunodeficiency virus type 1.
Journal: Antiviral research 20120601
Title: CCR5 inhibitors: emergence, success, and challenges.
Journal: Expert opinion on emerging drugs 20120601
Title: A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model.
Journal: PLoS pathogens 20120601
Title: CCR5 antagonist TD-0680 uses a novel mechanism for enhanced potency against HIV-1 entry, cell-mediated infection, and a resistant variant.
Journal: The Journal of biological chemistry 20120511
Title: Susceptibility of HIV type 2 primary isolates to CCR5 and CXCR4 monoclonal antibodies, ligands, and small molecule inhibitors.
Journal: AIDS research and human retroviruses 20120501
Title: Can the flow of medicines be improved? Fundamental pharmacokinetic and pharmacological principles toward improving Phase II survival.
Journal: Drug discovery today 20120501
Title: Naturally occurring resistance mutations to HIV-1 entry inhibitors in subtypes B, C, and CRF31_BC.
Journal: Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20120501
Title: Transmitted/founder and chronic subtype C HIV-1 use CD4 and CCR5 receptors with equal efficiency and are not inhibited by blocking the integrin α4β7.
Journal: PLoS pathogens 20120501
Title: Lower than expected maraviroc concentrations in cerebrospinal fluid exceed the wild-type CC chemokine receptor 5-tropic HIV-1 50% inhibitory concentration.
Journal: AIDS (London, England) 20120424
Title: Design and synthesis of a bivalent ligand to explore the putative heterodimerization of the mu opioid receptor and the chemokine receptor CCR5.
Journal: Organic & biomolecular chemistry 20120407
Title: Drug resistance and coreceptor usage in HIV type 1 subtype C-infected children initiating or failing highly active antiretroviral therapy in South Africa.
Journal: AIDS research and human retroviruses 20120401
Title: T-cell changes after a short-term exposure to maraviroc in HIV-infected patients are related to antiviral activity.
Journal: The Journal of infection 20120401
Title: Cell-cell transmission enables HIV-1 to evade inhibition by potent CD4bs directed antibodies.
Journal: PLoS pathogens 20120401
Title: [Integrase inhibitors and CCR5 receptor antagonists].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20120401
Title: Pharmacological modulation of chemokine receptor function.
Journal: British journal of pharmacology 20120301
Title: Efficacy of new antiretroviral drugs in treatment-experienced HIV-infected patients: a systematic review and meta-analysis of recent randomized controlled trials.
Journal: HIV medicine 20120301
Title: Once daily maraviroc 300 mg or 150 mg in combination with ritonavir-boosted darunavir 800/100 mg.
Journal: The Journal of antimicrobial chemotherapy 20120301
Title: [Allogeneic stem cell transplantation for acute myeloid leukemia and HIV infection--case 3/2012].
Journal: Deutsche medizinische Wochenschrift (1946) 20120301
Title: Novel approaches to inhibit HIV entry.
Journal: Viruses 20120201
Title: CNS effects of a CCR5 inhibitor in HIV-infected subjects: a pharmacokinetic and cerebral metabolite study.
Journal: The Journal of antimicrobial chemotherapy 20120101
Title: Modulatory effects of the CCR5 antagonist maraviroc on microglial pro-inflammatory activation elicited by gp120.
Journal: Journal of neurochemistry 20120101
Title: CCR5 antagonism in HIV infection: current concepts and future opportunities.
Journal: Annual review of medicine 20120101
Title: In vitro phenotypic susceptibility of HIV-2 clinical isolates to CCR5 inhibitors.
Journal: Antimicrobial agents and chemotherapy 20120101
Title: Drug safety evaluation of maraviroc for the treatment of HIV infection.
Journal: Expert opinion on drug safety 20120101
Title: Recent progress in small molecule CCR5 antagonists as potential HIV-1 entry inhibitors.
Journal: Current pharmaceutical design 20120101
Title: Interactions between prostaglandins, leukotrienes and HIV-1: possible implications for the central nervous system.
Journal: Retrovirology 20120101
Title: Immunologic effectiveness of maraviroc- and raltegravir-containing regimens (R+M+) versus raltegravir-based regimens that do not include maraviroc (R+M-).
Journal: Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 20120101
Title: Maraviroc, a chemokine receptor-5 antagonist, fails to demonstrate efficacy in the treatment of patients with rheumatoid arthritis in a randomized, double-blind placebo-controlled trial.
Journal: Arthritis research & therapy 20120101
Title: The epidemiology and clinical correlates of HIV-1 co-receptor tropism in non-subtype B infections from India, Uganda and South Africa.
Journal: Journal of the International AIDS Society 20120101
Title: Targets for inhibition of HIV replication: entry, enzyme action, release and maturation.
Journal: Intervirology 20120101
Title: Responses to switching to maraviroc-based antiretroviral therapy in treated patients with suppressed plasma HIV-1-RNA load.
Journal: Intervirology 20120101
Title: Faster HIV-1 disease progression among Brazilian individuals recently infected with CXCR4-utilizing strains.
Journal: PloS one 20120101
Title: Baseline susceptibility of primary HIV-2 to entry inhibitors.
Journal: Antiviral therapy 20120101
Title: Antiviral effect of maraviroc in semen: a case report.
Journal: Antiviral therapy 20120101
Title: Novel agents for the treatment of HIV-2 infection.
Journal: Antiviral therapy 20120101
Title: Review of the safety, efficacy, and pharmacokinetics of elvitegravir with an emphasis on resource-limited settings.
Journal: HIV/AIDS (Auckland, N.Z.) 20120101
Title: The use of preexposure treatments for HIV prophylaxis.
Journal: HIV/AIDS (Auckland, N.Z.) 20120101
Title: CCR5Δ32 genotype leads to a Th2 type directed immune response in ESRD patients.
Journal: PloS one 20120101
Title: A high performance liquid chromatographic assay of mefloquine in saliva after a single oral dose in healthy adult Africans.
Journal: Malaria journal 20120101
Title: The role of chemokines in mediating graft versus host disease: opportunities for novel therapeutics.
Journal: Frontiers in pharmacology 20120101
Title: Impaired maraviroc and raltegravir clearance in a human immunodeficiency virus-infected patient with end-stage liver disease and renal impairment: a management dilemma.
Journal: Pharmacotherapy 20120101
Title: In-depth characterization of viral isolates from plasma and cells compared with plasma circulating quasispecies in early HIV-1 infection.
Journal: PloS one 20120101
Title: Conference highlights of the 5th international workshop on HIV persistence during therapy, 6-9 December 2011, St. Maartin, West Indies.
Journal: AIDS research and therapy 20120101
Title: HIV-1 promotes intake of Leishmania parasites by enhancing phosphatidylserine-mediated, CD91/LRP-1-dependent phagocytosis in human macrophages.
Journal: PloS one 20120101
Title: Independent evolution of macrophage-tropism and increased charge between HIV-1 R5 envelopes present in brain and immune tissue.
Journal: Retrovirology 20120101
Title: Controversies in HIV cure research.
Journal: Journal of the International AIDS Society 20120101
Title: Analysis of high-depth sequence data for studying viral diversity: a comparison of next generation sequencing platforms using Segminator II.
Journal: BMC bioinformatics 20120101
Title: Incomplete immune recovery in HIV infection: mechanisms, relevance for clinical care, and possible solutions.
Journal: Clinical & developmental immunology 20120101
Title: Structural insights from binding poses of CCR2 and CCR5 with clinically important antagonists: a combined in silico study.
Journal: PloS one 20120101
Title: Impact of multi-targeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection.
Journal: PloS one 20120101
Title: HIV RNA suppression and immune restoration: can we do better?
Journal: Clinical & developmental immunology 20120101
Title: Monocytes contribute to differential immune pressure on R5 versus X4 HIV through the adipocytokine visfatin/NAMPT.
Journal: PloS one 20120101
Title: What is the future of CCR5 antagonists in rheumatoid arthritis?
Journal: Arthritis research & therapy 20120101
Title: Novel therapeutic strategies targeting HIV integrase.
Journal: BMC medicine 20120101
Title: Safety profile of maraviroc in patients coinfected with HIV-1 and hepatitis B or C included in the maraviroc expanded access program.
Journal: HIV clinical trials 20120101
Title: Molecular Understanding of HIV-1 Latency.
Journal: Advances in virology 20120101
Title: New option for management of HIV-1 infection in treatment-naive patients: once-daily, fixed-dose combination of rilpivirine-emtricitabine-tenofovir.
Journal: HIV/AIDS (Auckland, N.Z.) 20120101
Title: Impact of short-term HAART initiated during the chronic stage or shortly post-exposure on SIV infection of male genital organs.
Journal: PloS one 20120101
Title: Efficacy, stability, and biosafety of sifuvirtide gel as a microbicide candidate against HIV-1.
Journal: PloS one 20120101
Title: Antiretroviral drugs: critical issues and recent advances.
Journal: Indian journal of pharmacology 20120101
Title: Levels of soluble endothelial protein C receptor are associated with CD4+ changes in Maraviroc-treated HIV-infected patients.
Journal: PloS one 20120101
Title: Self-reported adherence supports patient preference for the single tablet regimen (STR) in the current cART era.
Journal: Patient preference and adherence 20120101
Title: Update on clinical and methodological recommendations for genotypic determination of HIV tropism to guide the usage of CCR5 antagonists.
Journal: AIDS reviews 20120101
Title: Alterations in cerebrospinal fluid chemokines are associated with maraviroc exposure and in vivo metabolites measurable by magnetic resonance spectroscopy.
Journal: HIV clinical trials 20120101
Title: Stochastic model of in-vivo X4 emergence during HIV infection: implications for the CCR5 inhibitor maraviroc.
Journal: PloS one 20120101
Title: A genotypic test for HIV-1 tropism combining Sanger sequencing with ultradeep sequencing predicts virologic response in treatment-experienced patients.
Journal: PloS one 20120101
Title: Non-aqueous silicone elastomer gels as a vaginal microbicide delivery system for the HIV-1 entry inhibitor maraviroc.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20111210
Title: Boosted tipranavir versus darunavir in treatment-experienced patients: observational data from the randomized POTENT trial.
Journal: Drugs in R&D 20111201
Title: Rescue of HIV-1 long-time archived X4 strains to escape maraviroc.
Journal: Antiviral research 20111201
Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Journal: PLoS computational biology 20111201
Title: Does GSS still maintain relevance on HAART outcome after the introduction of newest active antiretroviral drugs? 48 weeks results.
Journal: Current HIV research 20111201
Title: [Methods for determination of HIV tropism and their clinical use].
Journal: Enfermedades infecciosas y microbiologia clinica 20111201
Title: Microbicides: a new hope for HIV prevention.
Journal: The Indian journal of medical research 20111201
Title: How much do antiretroviral drugs penetrate into the central nervous system?
Journal: Journal of medicine and life 20111114
Title: Host factors mediating HIV-1 replication.
Journal: Virus research 20111101
Title: In vitro activity of antiretroviral drugs against Plasmodium falciparum.
Journal: Antimicrobial agents and chemotherapy 20111101
Title: In vitro effect of anti-human immunodeficiency virus CCR5 antagonist maraviroc on chemotactic activity of monocytes, macrophages and dendritic cells.
Journal: Clinical and experimental immunology 20111101
Title: Viral determinants of HIV-1 macrophage tropism.
Journal: Viruses 20111101
Title: Prospective CCR5 small molecule antagonist compound design using a combined mutagenesis/modeling approach.
Journal: Journal of the American Chemical Society 20111019
Title: Deep V3 sequencing for HIV type 1 tropism in treatment-naive patients: a reanalysis of the MERIT trial of maraviroc.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20111001
Title: Allosteric model of maraviroc binding to CC chemokine receptor 5 (CCR5).
Journal: The Journal of biological chemistry 20110923
Title: Synergistic activity profile of griffithsin in combination with tenofovir, maraviroc and enfuvirtide against HIV-1 clade C.
Journal: Virology 20110901
Title: A computational study of CYP3A4 mediated drug interaction profiles for anti-HIV drugs.
Journal: Journal of molecular modeling 20110801
Title: Pharmacokinetics of the raltegravir/maraviroc/etravirine combination.
Journal: The Journal of antimicrobial chemotherapy 20110801
Title: Identification and characterization of INCB9471, an allosteric noncompetitive small-molecule antagonist of C-C chemokine receptor 5 with potent inhibitory activity against monocyte migration and HIV-1 infection.
Journal: The Journal of pharmacology and experimental therapeutics 20110701
Title: Cell disposition of raltegravir and newer antiretrovirals in HIV-infected patients: high inter-individual variability in raltegravir cellular penetration.
Journal: The Journal of antimicrobial chemotherapy 20110701
Title: A role for the chemokine RANTES in regulating CD8 T cell responses during chronic viral infection.
Journal: PLoS pathogens 20110701
Title: Common adverse effects of antiretroviral therapy for HIV disease.
Journal: American family physician 20110615
Title: Novel 4,4-disubstituted piperidine-based C-C chemokine receptor-5 inhibitors with high potency against human immunodeficiency virus-1 and an improved human ether-a-go-go related gene (hERG) profile.
Journal: Journal of medicinal chemistry 20110609
Title: Agonist-induced internalization of CC chemokine receptor 5 as a mechanism to inhibit HIV replication.
Journal: The Journal of pharmacology and experimental therapeutics 20110601
Title: Synergistic inhibition of R5 HIV-1 by maraviroc and CCR5 antibody HGS004 in primary cells: implications for treatment and prevention.
Journal: AIDS (London, England) 20110601
Title: Maraviroc intensification for suboptimal CD4⁺ T cell response in a perinatally HIV-infected adolescent.
Journal: AIDS (London, England) 20110601
Title: Lessons from maraviroc clinical trials.
Journal: Expert review of anti-infective therapy 20110601
Title: Detection of inferred CCR5- and CXCR4-using HIV-1 variants and evolutionary intermediates using ultra-deep pyrosequencing.
Journal: PLoS pathogens 20110601
Title: HIV-1 efficient entry in inner foreskin is mediated by elevated CCL5/RANTES that recruits T cells and fuels conjugate formation with Langerhans cells.
Journal: PLoS pathogens 20110601
Title: Single and multiple dose pharmacokinetics of maraviroc in saliva, semen, and rectal tissue of healthy HIV-negative men.
Journal: The Journal of infectious diseases 20110515
Title: HIV-1 entry inhibition by small-molecule CCR5 antagonists: a combined molecular modeling and mutant study using a high-throughput assay.
Journal: Virology 20110510
Title: A combination of polymorphic mutations in V3 loop of HIV-1 gp120 can confer noncompetitive resistance to maraviroc.
Journal: Virology 20110510
Title: [CCR5 antagonist Maraviroc: effective and well tolerated. 'A very promising substance'].
Journal: MMW Fortschritte der Medizin 20110505
Title: [Utilizing the potential of maraviroc early. 'Clear in second line therapy' (interview by Dr. Felicitas Zorn)].
Journal: MMW Fortschritte der Medizin 20110505
Title: Analysis of co-receptor usage of circulating viral and proviral HIV genome quasispecies by ultra-deep pyrosequencing in patients who are candidates for CCR5 antagonist treatment.
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20110501
Title: Rapid analysis of pharmacology for infectious diseases.
Journal: Current topics in medicinal chemistry 20110501
Title: HIV-1 integrase inhibitor resistance and its clinical implications.
Journal: The Journal of infectious diseases 20110501
Title: [Characteristics of antiretroviral drugs].
Journal: Enfermedades infecciosas y microbiologia clinica 20110501
Title: Combinations of 3-hydroxyphthalic anhydride-modified ovalbumin with antiretroviral drug-based microbicide candidates display synergistic and complementary effects against HIV-1 infection.
Journal: Journal of acquired immune deficiency syndromes (1999) 20110415
Title: Proper laboratory notebook practices: protecting your intellectual property.
Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20110401
Title: Chemokine receptor CCR5: from AIDS to atherosclerosis.
Journal: British journal of pharmacology 20110401
Title: Approaches for understanding and predicting drug interactions in human immunodeficiency virus-infected patients.
Journal: Expert opinion on drug metabolism & toxicology 20110401
Title: Clinical pharmacokinetic and pharmacodynamic profile of the HIV integrase inhibitor elvitegravir.
Journal: Clinical pharmacokinetics 20110401
Title: HIV-1 dual/mixed tropic isolates show different genetic and phenotypic characteristics and response to maraviroc in vitro.
Journal: Antiviral research 20110401
Title: Durability and safety of a novel salvage therapy in R5-tropic HIV-infected patients: maraviroc, raltegravir, etravirine.
Journal: Journal of acquired immune deficiency syndromes (1999) 20110401
Title: CXCR4 and CCR5 ligands cooperate in monocyte and lymphocyte migration and in inhibition of dual-tropic (R5/X4) HIV-1 infection.
Journal: European journal of immunology 20110401
Title: Maraviroc is able to inhibit dual-R5 viruses in a dual/mixed HIV-1-infected patient.
Journal: The Journal of antimicrobial chemotherapy 20110401
Title: Potential of novel antiretrovirals to modulate expression and function of drug transporters in vitro.
Journal: The Journal of antimicrobial chemotherapy 20110401
Title: Engineering HIV-resistant human CD4+ T cells with CXCR4-specific zinc-finger nucleases.
Journal: PLoS pathogens 20110401
Title: Clinical management of HIV drug resistance.
Journal: Viruses 20110401
Title: CCR5 blockade in combination with cyclosporine increased cardiac graft survival and generated alternatively activated macrophages in primates.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20110315
Title: CCR5 antibodies HGS004 and HGS101 preferentially inhibit drug-bound CCR5 infection and restore drug sensitivity of Maraviroc-resistant HIV-1 in primary cells.
Journal: Virology 20110301
Title: Synthesis and evaluation of 2-phenyl-1,4-butanediamine-based CCR5 antagonists for the treatment of HIV-1.
Journal: Bioorganic & medicinal chemistry letters 20110301
Title: Theoretical studies on the interactions and interferences of HIV-1 glycoprotein gp120 and its coreceptor CCR5.
Journal: Journal of chemical information and modeling 20110227
Title: New insights into the mechanisms whereby low molecular weight CCR5 ligands inhibit HIV-1 infection.
Journal: The Journal of biological chemistry 20110218
Title: The use of the SAEM algorithm in MONOLIX software for estimation of population pharmacokinetic-pharmacodynamic-viral dynamics parameters of maraviroc in asymptomatic HIV subjects.
Journal: Journal of pharmacokinetics and pharmacodynamics 20110201
Title: Emerging antiretroviral drug interactions.
Journal: The Journal of antimicrobial chemotherapy 20110201
Title: Discordance rates between Trofile test and short-term virological response to maraviroc.
Journal: Antiviral research 20110201
Title: Direct measurement of thermal stability of expressed CCR5 and stabilization by small molecule ligands.
Journal: Biochemistry 20110201
Title: Efficacy and safety of nucleoside reverse transcriptase inhibitor-sparing salvage therapy for multidrug-resistant HIV-1 infection based on new-class and new-generation antiretrovirals.
Journal: The Journal of antimicrobial chemotherapy 20110201
Title: Comparison of phenotypic and genotypic tropism determination in triple-class-experienced HIV patients eligible for maraviroc treatment.
Journal: The Journal of antimicrobial chemotherapy 20110201
Title: Small molecule HIV entry inhibitors: Part I. Chemokine receptor antagonists: 2004 - 2010.
Journal: Expert opinion on therapeutic patents 20110201
Title: Deep sequencing to infer HIV-1 co-receptor usage: application to three clinical trials of maraviroc in treatment-experienced patients.
Journal: The Journal of infectious diseases 20110115
Title: An imidazopiperidine series of CCR5 antagonists for the treatment of HIV: the discovery of N-{(1S)-1-(3-fluorophenyl)-3-[(3-endo)-3-(5-isobutyryl-2-methyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridin-1-yl)-8-azabicyclo[3.2.1]oct-8-yl]propyl}acetamide (PF-232798).
Journal: Journal of medicinal chemistry 20110113
Title: Recent advances in antiretroviral drugs.
Journal: Expert opinion on pharmacotherapy 20110101
Title: Indications for the use of next-generation antiretroviral drugs in current clinical practice.
Journal: Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20110101
Title: Long-term CD4+ T-cell count evolution after switching from regimens including HIV nucleoside reverse transcriptase inhibitors (NRTI) plus protease inhibitors to regimens containing NRTI plus non-NRTI or only NRTI.
Journal: BMC infectious diseases 20110101
Title: Introducing the issue on 'differential use of CCR5 versus CXCR4 by HIV-1. Pathogenic, translational and clinical open questions'.
Journal: Journal of translational medicine 20110101
Title: R5X4 HIV-1 coreceptor use in primary target cells: implications for coreceptor entry blocking strategies.
Journal: Journal of translational medicine 20110101
Title: Natural anti-CCR5 antibodies in HIV-infection and -exposure.
Journal: Journal of translational medicine 20110101
Title: Clinical significance of HIV-1 coreceptor usage.
Journal: Journal of translational medicine 20110101
Title: Clinical use of CCR5 inhibitors in HIV and beyond.
Journal: Journal of translational medicine 20110101
Title: [Variability in HIV viral tropism determination using different genotypic algorithms in patients infected with B versus non-B HIV-1 subtypes].
Journal: Enfermedades infecciosas y microbiologia clinica 20110101
Title: Penicillium marneffei Infection in AIDS.
Journal: Pathology research international 20110101
Title: Update on microbicide research and development - seeking new HIV prevention tools for women.
Journal: European journal of medical research 20110101
Title: Prevalence of potential drug-drug interactions involving antiretroviral drugs in a large Kenyan cohort.
Journal: PloS one 20110101
Title: Maraviroc can improve lipid profiles in dyslipidemic patients with HIV: results from the MERIT trial.
Journal: HIV clinical trials 20110101
Title: The costs of full suppression of plasma HIV RNA in highly antiretroviral-experienced patients.
Journal: AIDS reviews 20110101
Title: Susceptibility of HIV-1 subtypes B', CRF07_BC and CRF01_AE that are predominantly circulating in China to HIV-1 entry inhibitors.
Journal: PloS one 20110101
Title: Genetic characteristics, coreceptor usage potential and evolution of Nigerian HIV-1 subtype G and CRF02_AG isolates.
Journal: PloS one 20110101
Title: Use of maraviroc-, raltegravir-, and etravirine-containing regimens in treatment-experienced patients: a case-series study.
Journal: Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 20110101
Title: HIV quasispecies dynamics during pro-active treatment switching: impact on multi-drug resistance and resistance archiving in latent reservoirs.
Journal: PloS one 20110101
Title: Comparison of intima-media thickness and ophthalmic artery resistance index for assessing subclinical atherosclerosis in HIV-1-infected patients.
Journal: Cardiovascular ultrasound 20110101
Title: Results of antiretroviral treatment interruption and intensification in advanced multi-drug resistant HIV infection from the OPTIMA trial.
Journal: PloS one 20110101
Title: Antiretroviral Therapy for HIV-2 Infection: Recommendations for Management in Low-Resource Settings.
Journal: AIDS research and treatment 20110101
Title: Outcomes of Universal Access to Antiretroviral Therapy (ART) in Georgia.
Journal: AIDS research and treatment 20110101
Title: Mutations in gp41 are correlated with coreceptor tropism but do not improve prediction methods substantially.
Journal: Antiviral therapy 20110101
Title: Baseline CD4(+) T-cell counts and weighted background susceptibility scores strongly predict response to maraviroc regimens in treatment-experienced patients.
Journal: Antiviral therapy 20110101
Title: Create a translational medicine knowledge repository--research downsizing, mergers and increased outsourcing have reduced the depth of in-house translational medicine expertise and institutional memory at many pharmaceutical and biotech companies: how will they avoid relearning old lessons?
Journal: Journal of translational medicine 20110101
Title: Selected amino acid mutations in HIV-1 B subtype gp41 are associated with specific gp120v₃ signatures in the regulation of co-receptor usage.
Journal: Retrovirology 20110101
Title: Genotypic tropism testing by massively parallel sequencing: qualitative and quantitative analysis.
Journal: BMC medical informatics and decision making 20110101
Title: Clinical utility of maraviroc.
Journal: Clinical drug investigation 20110101
Title: Marked increase in etravirine and saquinavir plasma concentrations during atovaquone/proguanil prophylaxis.
Journal: Malaria journal 20110101
Title: Contraception in HIV-positive female adolescents.
Journal: AIDS research and therapy 20110101
Title: Conformational alterations in the CD4 binding cavity of HIV-1 gp120 influencing gp120-CD4 interactions and fusogenicity of HIV-1 envelopes derived from brain and other tissues.
Journal: Retrovirology 20110101
Title: HIV and HAART-Associated Dyslipidemia.
Journal: The open cardiovascular medicine journal 20110101
Title: Solution structure of LC4 transmembrane segment of CCR5.
Journal: PloS one 20110101
Title: Estimating the threshold surface density of Gp120-CCR5 complexes necessary for HIV-1 envelope-mediated cell-cell fusion.
Journal: PloS one 20110101
Title: Inhibition of HIV-1 Env-Mediated Cell-Cell Fusion by Lectins, Peptide T-20, and Neutralizing Antibodies.
Journal: The open virology journal 20110101
Title: A topical microbicide gel formulation of CCR5 antagonist maraviroc prevents HIV-1 vaginal transmission in humanized RAG-hu mice.
Journal: PloS one 20110101
Title: Humanized Rag1-/- γc-/- mice support multilineage hematopoiesis and are susceptible to HIV-1 infection via systemic and vaginal routes.
Journal: PloS one 20110101
Title: Validation of case-finding algorithms derived from administrative data for identifying adults living with human immunodeficiency virus infection.
Journal: PloS one 20110101
Title: Should patents for antiretrovirals be waived in the developing world? Annual Varsity Medical Debate--London, 21 January 2011.
Journal: Philosophy, ethics, and humanities in medicine : PEHM 20110101
Title: Genotypic prediction of HIV-1 subtype D tropism.
Journal: Retrovirology 20110101
Title: Resistance to the CCR5 inhibitor 5P12-RANTES requires a difficult evolution from CCR5 to CXCR4 coreceptor use.
Journal: PloS one 20110101
Title: [Analysis of the prevalence of CCR5 coreceptor antagonist resistance mutations among HIV-1 variants in Russia].
Journal: Voprosy virusologii 20110101
Title: Pre-exposure prophylaxis of HIV.
Journal: Indian journal of sexually transmitted diseases and AIDS 20110101
Title: Investigation of griffithsin's interactions with human cells confirms its outstanding safety and efficacy profile as a microbicide candidate.
Journal: PloS one 20110101
Title: The utility of the new generation of humanized mice to study HIV-1 infection: transmission, prevention, pathogenesis, and treatment.
Journal: Retrovirology 20110101
Title: Genotypic and functional properties of early infant HIV-1 envelopes.
Journal: Retrovirology 20110101
Title: Origin and epidemiological history of HIV-1 CRF14_BG.
Journal: PloS one 20110101
Title: Resource utilization and cost-effectiveness of counselor- vs. provider-based rapid point-of-care HIV screening in the emergency department.
Journal: PloS one 20110101
Title: [Our experience with maraviroc treatment in HIV positive patients].
Journal: Casopis lekaru ceskych 20110101
Title: A comparison of parallel pyrosequencing and sanger clone-based sequencing and its impact on the characterization of the genetic diversity of HIV-1.
Journal: PloS one 20110101
Title: HIV-1 predisposed to acquiring resistance to maraviroc (MVC) and other CCR5 antagonists in vitro has an inherent, low-level ability to utilize MVC-bound CCR5 for entry.
Journal: Retrovirology 20110101
Title: An inducible cell-cell fusion system with integrated ability to measure the efficiency and specificity of HIV-1 entry inhibitors.
Journal: PloS one 20110101
Title: It is time to consider third-line options in antiretroviral-experienced paediatric patients?
Journal: Journal of the International AIDS Society 20110101
Title: 8-Modified-2'-deoxyadenosine analogues induce delayed polymerization arrest during HIV-1 reverse transcription.
Journal: PloS one 20110101
Title: Combined phytochemistry and chemotaxis assays for identification and mechanistic analysis of anti-inflammatory phytochemicals in Fallopia japonica.
Journal: PloS one 20110101
Title: Safety, efficacy, and pharmacokinetics of rilpivirine: systematic review with an emphasis on resource-limited settings.
Journal: HIV/AIDS (Auckland, N.Z.) 20110101
Title: Role of raltegravir in the management of HIV-1 infection.
Journal: HIV/AIDS (Auckland, N.Z.) 20110101
Title: Pharmacokinetics of antiretroviral drugs in anatomical sanctuary sites: the fetal compartment (placenta and amniotic fluid).
Journal: Antiviral therapy 20110101
Title: Pharmacokinetics of antiretroviral drugs in anatomical sanctuary sites: the male and female genital tract.
Journal: Antiviral therapy 20110101
Title: SHIV-162P3 infection of rhesus macaques given maraviroc gel vaginally does not involve resistant viruses.
Journal: PloS one 20110101
Title: Applications of next-generation sequencing technologies to diagnostic virology.
Journal: International journal of molecular sciences 20110101
Title: Intensification of antiretroviral therapy with a CCR5 antagonist in patients with chronic HIV-1 infection: effect on T cells latently infected.
Journal: PloS one 20110101
Title: In vitro downregulation of matrix metalloproteinase-9 in rat glial cells by CCR5 antagonist maraviroc: therapeutic implication for HIV brain infection.
Journal: PloS one 20110101
Title: Modeling dynamic interactions between pre-exposure prophylaxis interventions & treatment programs: predicting HIV transmission & resistance.
Journal: Scientific reports 20110101
Title: Grand challenges.
Journal: Frontiers in immunology 20110101
Title: Clinical Use of Inhibitors of HIV-1 Integration: Problems and Prospects.
Journal: Acta naturae 20110101
Title: Two-year safety and virologic efficacy of maraviroc in treatment-experienced patients with CCR5-tropic HIV-1 infection: 96-week combined analysis of MOTIVATE 1 and 2.
Journal: Journal of acquired immune deficiency syndromes (1999) 20101215
Title: Maraviroc concentrations in cerebrospinal fluid in HIV-infected patients.
Journal: Journal of acquired immune deficiency syndromes (1999) 20101215
Title: Treatment intensification has no effect on the HIV-1 central nervous system infection in patients on suppressive antiretroviral therapy.
Journal: Journal of acquired immune deficiency syndromes (1999) 20101215
Title: Maraviroc concentrations in seminal plasma in HIV-infected patients.
Journal: Journal of acquired immune deficiency syndromes (1999) 20101215
Title: C-C chemokine receptor type 5 (CCR5) utilization of transmitted and early founder human immunodeficiency virus type 1 envelopes and sensitivity to small-molecule CCR5 inhibitors.
Journal: The Journal of general virology 20101201
Title: Evolution of CCR5 antagonist resistance in an HIV-1 subtype C clinical isolate.
Journal: Journal of acquired immune deficiency syndromes (1999) 20101201
Title: Primary resistance to maraviroc in a large set of R5-V3 viral sequences from HIV-1-infected patients.
Journal: The Journal of antimicrobial chemotherapy 20101201
Title: TROCAI (tropism coreceptor assay information): a new phenotypic tropism test and its correlation with Trofile enhanced sensitivity and genotypic approaches.
Journal: Journal of clinical microbiology 20101201
Title: Evaluation of primary resistance to HIV entry inhibitors among brazilian patients failing reverse transcriptase/protease inhibitors treatment reveal high prevalence of maraviroc resistance-related mutations.
Journal: AIDS research and human retroviruses 20101201
Title: Glioblastoma: synergy of growth promotion between CCL5 and NK-1R can be thwarted by blocking CCL5 with miraviroc, an FDA approved anti-HIV drug and blocking NK-1R with aprepitant, an FDA approved anti-nausea drug.
Journal: Journal of clinical pharmacy and therapeutics 20101201
Title: An LC-MS-MS method for quantitative determination of maraviroc (UK-427,857) in human plasma, urine and cerebrospinal fluid.
Journal: Biomedical chromatography : BMC 20101201
Title: Cost-effectiveness of maraviroc for antiretroviral treatment-experienced HIV-infected individuals in Mexico.
Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20101201
Title: [Pharmacological profile and clinical findings of Maraviroc (Celsentri® Tablets)].
Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20101201
Title: The evolutionary analysis of emerging low frequency HIV-1 CXCR4 using variants through time--an ultra-deep approach.
Journal: PLoS computational biology 20101201
Title: Maraviroc is a substrate for OATP1B1 in vitro and maraviroc plasma concentrations are influenced by SLCO1B1 521 T>C polymorphism.
Journal: Pharmacogenetics and genomics 20101201
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20101201
Title: Comparison of the Mechanisms of Drug Resistance among HIV, Hepatitis B, and Hepatitis C.
Journal: Viruses 20101201
Title: Cost-effectiveness of optimized background therapy plus maraviroc for previously treated patients with R5 HIV-1 infection from the perspective of the Spanish health care system.
Journal: Clinical therapeutics 20101201
Title: A report from the XVIII International AIDS Conference. (July 18-23, 2010-Vienna, Austria).
Journal: Drugs of today (Barcelona, Spain : 1998) 20101201
Title: Maraviroc does not affect humoral response to the pandemic influenza A-H1N1v 2009 adjuvanted vaccine in HIV-1-infected patients.
Journal: AIDS (London, England) 20101127
Title: Hepatic safety and tolerability in the maraviroc clinical development program.
Journal: AIDS (London, England) 20101113
Title: Recognition and management of significant drug interactions in HIV patients: challenges in using available data to guide therapy.
Journal: Clinical pharmacology and therapeutics 20101101
Title: Emerging concepts and approaches for chemokine-receptor drug discovery.
Journal: Expert opinion on drug discovery 20101101
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20101101
Title: It's official...but not infallible.
Journal: Prescrire international 20101101
Title: Maraviroc first-line therapy for HIV infection. Too risky.
Journal: Prescrire international 20101101
Title: Population-based V3 genotypic tropism assay: a retrospective analysis using screening samples from the A4001029 and MOTIVATE studies.
Journal: AIDS (London, England) 20101023
Title: Maternal-fetal pharmacokinetics and dynamics of a single intrapartum dose of maraviroc in rhesus macaques.
Journal: Antimicrobial agents and chemotherapy 20101001
Title: A maraviroc-resistant HIV-1 with narrow cross-resistance to other CCR5 antagonists depends on both N-terminal and extracellular loop domains of drug-bound CCR5.
Journal: Journal of virology 20101001
Title: Novel antiretroviral combinations in treatment-experienced patients with HIV infection: rationale and results.
Journal: Drugs 20100910
Title: An altered and more efficient mechanism of CCR5 engagement contributes to macrophage tropism of CCR5-using HIV-1 envelopes.
Journal: Virology 20100901
Title: Protection of rhesus macaques from vaginal infection by vaginally delivered maraviroc, an inhibitor of HIV-1 entry via the CCR5 co-receptor.
Journal: The Journal of infectious diseases 20100901
Title: Long-term immunovirogical effect and tolerability of a maraviroc-containing regimen in routine clinical practice.
Journal: Current HIV research 20100901
Title: Maraviroc-containing regimen suppresses HIV replication in the cerebrospinal fluid of patients with neurological symptoms.
Journal: AIDS (London, England) 20100824
Title: CD4+ T-cell restoration after 48 weeks in the maraviroc treatment-experienced trials MOTIVATE 1 and 2.
Journal: Journal of acquired immune deficiency syndromes (1999) 20100801
Title: Characterization of a SHIV162P3 variant evolved in an infected rhesus macaque with persistent plasma viremia.
Journal: Virus research 20100801
Title: Improved detection of CXCR4-using HIV by V3 genotyping: application of population-based and 'deep' sequencing to plasma RNA and proviral DNA.
Journal: Journal of acquired immune deficiency syndromes (1999) 20100801
Title: Evaluation of the genotypic prediction of HIV-1 coreceptor use versus a phenotypic assay and correlation with the virological response to maraviroc: the ANRS GenoTropism study.
Journal: Antimicrobial agents and chemotherapy 20100801
Title: Pharmacogenetic testing and therapeutic drug monitoring are complementary tools for optimal individualization of drug therapy.
Journal: European journal of clinical pharmacology 20100801
Title: Downregulation of leukocyte migration after treatment with CCR5 antagonist maraviroc.
Journal: Journal of acquired immune deficiency syndromes (1999) 20100801
Title: Development and application of a simple LC-MS method for the determination of plasma maraviroc concentrations.
Journal: The journal of medical investigation : JMI 20100801
Title: A novel CCR5 mutation common in sooty mangabeys reveals SIVsmm infection of CCR5-null natural hosts and efficient alternative coreceptor use in vivo.
Journal: PLoS pathogens 20100801
Title: Dynamics of HIV tropism under suppressive antiretroviral therapy: implications for tropism testing in subjects with undetectable viraemia.
Journal: The Journal of antimicrobial chemotherapy 20100701
Title: Hemodynamic effects of single-dose vardenafil in subjects receiving maraviroc.
Journal: Journal of acquired immune deficiency syndromes (1999) 20100701
Title: Short communication: antiretroviral therapy resistance mutations present in the HIV type 1 subtype C pol and env regions from therapy-naive patients in Zambia.
Journal: AIDS research and human retroviruses 20100701
Title: Role of CXCR4 in HIV infection and its potential as a therapeutic target.
Journal: Future microbiology 20100701
Title: Patterns of HIV-1 protein interaction identify perturbed host-cellular subsystems.
Journal: PLoS computational biology 20100701
Title: Maraviroc: a review of its use in the management of CCR5-tropic HIV-1 infection.
Journal: Drugs 20100618
Title: Validation of a rapid and sensitive high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) assay for the simultaneous determination of existing and new antiretroviral compounds.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100601
Title: Shift in phenotypic susceptibility suggests a competition mechanism in a case of acquired resistance to maraviroc.
Journal: AIDS (London, England) 20100601
Title: HIV-1 tropism.
Journal: Protein & cell 20100601
Title: Novel hexahydropyrrolo[3,4-c]pyrrole CCR5 antagonists.
Journal: Bioorganic & medicinal chemistry letters 20100515
Title: Clinical outcome in resistant HIV-2 infection treated with raltegravir and maraviroc.
Journal: Antiviral research 20100501
Title: Protection against HIV-envelope-induced neuronal cell destruction by HIV attachment inhibitors.
Journal: Archives of virology 20100501
Title: Raltegravir plasma concentrations in treatment-experienced patients receiving salvage regimens based on raltegravir with and without maraviroc coadministration.
Journal: The Annals of pharmacotherapy 20100501
Title: Treatment of HIV infection with the CCR5 antagonist maraviroc.
Journal: Expert opinion on pharmacotherapy 20100501
Title: [CCR5-antagonists: contribution of a new antiretroviral class to the management of HIV infection].
Journal: Medecine et maladies infectieuses 20100501
Title: Inhibition of HIV-1 replication by isoxazolidine and isoxazole sulfonamides.
Journal: Chemical biology & drug design 20100501
Title: HIV-1 Entry, Inhibitors, and Resistance.
Journal: Viruses 20100501
Title: Using density functional theory to rationalise the mass spectral fragmentation of maraviroc and its metabolites.
Journal: Rapid communications in mass spectrometry : RCM 20100415
Title: CCR5 antagonists: host-targeted antiviral agents for the treatment of HIV infection, 4 years on.
Journal: Antiviral chemistry & chemotherapy 20100414
Title: Basic PK/PD principles of drug effects in circular/proliferative systems for disease modelling.
Journal: Journal of pharmacokinetics and pharmacodynamics 20100401
Title: Are the proposed env mutations actually associated with resistance to maraviroc?
Journal: Journal of acquired immune deficiency syndromes (1999) 20100401
Title: Prediction of co-receptor usage of HIV-1 from genotype.
Journal: PLoS computational biology 20100401
Title: HIV-1 RT Inhibitors with a Novel Mechanism of Action: NNRTIs that Compete with the Nucleotide Substrate.
Journal: Viruses 20100401
Title: Raltegravir, maraviroc, etravirine: an effective protease inhibitor and nucleoside reverse transcriptase inhibitor-sparing regimen for salvage therapy in HIV-infected patients with triple-class experience.
Journal: AIDS (London, England) 20100327
Title: A lectin isolated from bananas is a potent inhibitor of HIV replication.
Journal: The Journal of biological chemistry 20100319
Title: Maraviroc versus efavirenz, both in combination with zidovudine-lamivudine, for the treatment of antiretroviral-naive subjects with CCR5-tropic HIV-1 infection.
Journal: The Journal of infectious diseases 20100315
Title: Maraviroc for treatment-naive patients with HIV-1 infection: is the glass half empty or half full?
Journal: The Journal of infectious diseases 20100315
Title: Clinical implications of genotypic resistance to the newer antiretroviral drugs in HIV-1-infected patients with virological failure.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20100315
Title: Different selection patterns of resistance and cross-resistance to HIV-1 agents targeting CCR5.
Journal: The Journal of antimicrobial chemotherapy 20100301
Title: Anti-chemokine small molecule drugs: a promising future?
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Title: Evaluation of a 3-amino-8-azabicyclo[3.2.1]octane replacement in the CCR5 antagonist maraviroc.
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Title: Novel CCR5 antagonists for the treatment of HIV infection: a review of compounds patented in 2006 - 2008.
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Title: [Current topics on drug-resistant HIV in Japan].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20100301
Title: Drug-class specific impact of antivirals on the reproductive capacity of HIV.
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Title: Pharmacokinetic interaction of ritonavir-boosted elvitegravir and maraviroc.
Journal: Journal of acquired immune deficiency syndromes (1999) 20100201
Title: A validated high-performance liquid chromatography-ultraviolet method for quantification of the CCR5 inhibitor maraviroc in plasma of HIV-infected patients.
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Title: HIV entry inhibitors: progress in development and application.
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Title: [The newest developments in anti-HIV-1 drugs].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20100201
Title: CCR5: From Natural Resistance to a New Anti-HIV Strategy.
Journal: Viruses 20100201
Title: Pharmacokinetics and drug-drug interactions of antiretrovirals: an update.
Journal: Antiviral research 20100101
Title: Entry inhibitors in the treatment of HIV-1 infection.
Journal: Antiviral research 20100101
Title: Long-lasting enfuvirtide carrier pentasaccharide conjugates with potent anti-human immunodeficiency virus type 1 activity.
Journal: Antimicrobial agents and chemotherapy 20100101
Title: Foscarnet as salvage therapy in HIV-2-infected patient with antiretroviral treatment failure.
Journal: Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20100101
Title: HIV type 1 from a patient with baseline resistance to CCR5 antagonists uses drug-bound receptor for entry.
Journal: AIDS research and human retroviruses 20100101
Title: Assessment of the pharmacokinetics of co-administered maraviroc and raltegravir.
Journal: British journal of clinical pharmacology 20100101
Title: Formal reasoning on qualitative models of coinfection of HIV and Tuberculosis and HAART therapy.
Journal: BMC bioinformatics 20100101
Title: Towards a Patent Pool for HIV Medicines: The Background.
Journal: The open AIDS journal 20100101
Title: Patent Pooling for Promoting Access to Antiretroviral Drugs (ARVs) - A Strategic Option for India.
Journal: The open AIDS journal 20100101
Title: Pooling ARV Drug Patents: A Pro-Access Fitting Strategy?
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Title: Profile of etravirine for the treatment of HIV infection.
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Title: [Approach to establishing and evaluating clinical relevance of drug interactions in HIV patients: 2009 update].
Journal: Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20100101
Title: Frequent CXCR4 tropism of HIV-1 subtype A and CRF02_AG during late-stage disease--indication of an evolving epidemic in West Africa.
Journal: Retrovirology 20100101
Title: HIV-1 fusion inhibitor peptides enfuvirtide and T-1249 interact with erythrocyte and lymphocyte membranes.
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Title: Molecular mechanisms of HIV-1 persistence in the monocyte-macrophage lineage.
Journal: Retrovirology 20100101
Title: Maleic anhydride-modified chicken ovalbumin as an effective and inexpensive anti-HIV microbicide candidate for prevention of HIV sexual transmission.
Journal: Retrovirology 20100101
Title: Optimal management of cytomegalovirus retinitis in patients with AIDS.
Journal: Clinical ophthalmology (Auckland, N.Z.) 20100101
Title: Forecasting drug utilization and expenditure in a metropolitan health region.
Journal: BMC health services research 20100101
Title: Incorporation of podoplanin into HIV released from HEK-293T cells, but not PBMC, is required for efficient binding to the attachment factor CLEC-2.
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Title: Semen may harbor HIV despite effective HAART: another piece in the puzzle.
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Title: Recent key advances in human immunodeficiency virus medicine and implications for China.
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Title: Effects of CC chemokine receptor 5 (CCR5) inhibitors on the dynamics of CCR5 and CC-chemokine-CCR5 interactions.
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Title: A microsimulation of the cost-effectiveness of maraviroc for antiretroviral treatment-experienced HIV-infected individuals.
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Title: Positive selection of HIV host factors and the evolution of lentivirus genes.
Journal: BMC evolutionary biology 20100101
Title: Comparative determination of HIV-1 co-receptor tropism by Enhanced Sensitivity Trofile, gp120 V3-loop RNA and DNA genotyping.
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Title: Comparison of HIV-1 genotypic resistance test interpretation systems in predicting virological outcomes over time.
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Title: Co-receptor tropism prediction among 1045 Indian HIV-1 subtype C sequences: Therapeutic implications for India.
Journal: AIDS research and therapy 20100101
Title: Acyclovir inhibition of IDO to decrease Tregs as a glioblastoma treatment adjunct.
Journal: Journal of neuroinflammation 20100101
Title: Maraviroc in treatment-experienced patients with HIV-1 infection - experience from routine clinical practice.
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Title: Efficacy and safety of maraviroc versus efavirenz, both with zidovudine/lamivudine: 96-week results from the MERIT study.
Journal: HIV clinical trials 20100101
Title: Impact of baseline antiretroviral resistance status on efficacy outcomes among patients receiving maraviroc plus optimized background therapy in the MOTIVATE 1 and 2 trials.
Journal: HIV clinical trials 20100101
Title: Anti-inflammatory effect of maraviroc in an HIV-infected patient with concomitant myositis: a case report.
Journal: Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 20100101
Title: HIV-1 V3 envelope deep sequencing for clinical plasma specimens failing in phenotypic tropism assays.
Journal: AIDS research and therapy 20100101
Title: Structure activity relationship of dendrimer microbicides with dual action antiviral activity.
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Title: From bench to clinic: accessing promising investigational medications for patients with HIV infection in an urban family health center.
Journal: Journal of the American Board of Family Medicine : JABFM 20100101
Title: Clinical perspective on antiretroviral drug-drug interactions with the non-nucleoside reverse transcriptase inhibitor etravirine.
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Title: Genotypic determination of HIV tropism - clinical and methodological recommendations to guide the therapeutic use of CCR5 antagonists.
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Title: Assessing the performance of a computer-based policy model of HIV and AIDS.
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Title: Clinical, virological and immunological responses in Danish HIV patients receiving raltegravir as part of a salvage regimen.
Journal: Clinical epidemiology 20100101
Title: Accurate and efficient gp120 V3 loop structure based models for the determination of HIV-1 co-receptor usage.
Journal: BMC bioinformatics 20100101
Title: Effects of maraviroc and efavirenz on markers of immune activation and inflammation and associations with CD4+ cell rises in HIV-infected patients.
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Title: Progress in antiretroviral drug delivery using nanotechnology.
Journal: International journal of nanomedicine 20100101
Title: Co-receptor usage and prediction of V3 genotyping algorithms in HIV-1 subtype B' from paid blood donors experienced anti-retroviral therapy in Chinese central province.
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Title: Antiretroviral therapy optimisation without genotype resistance testing: a perspective on treatment history based models.
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Title: Structure of HIV-1 quasi-species as early indicator for switches of co-receptor tropism.
Journal: AIDS research and therapy 20100101
Title: Early development of non-hodgkin lymphoma following initiation of newer class antiretroviral therapy among HIV-infected patients - implications for immune reconstitution.
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Title: Transmitted drug resistance in persons with acute/early HIV-1 in San Francisco, 2002-2009.
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Title: Grifonin-1: a small HIV-1 entry inhibitor derived from the algal lectin, Griffithsin.
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Title: Clinical management of treatment-experienced, HIV/AIDS patients in the combination antiretroviral therapy era.
Journal: PharmacoEconomics 20100101
Title: Oral pre-exposure prophylaxis by anti-retrovirals raltegravir and maraviroc protects against HIV-1 vaginal transmission in a humanized mouse model.
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Title: Incidence of Severe Hepatotoxicity Related to Antiretroviral Therapy in HIV/HCV Coinfected Patients.
Journal: AIDS research and treatment 20100101
Title: Lipid Metabolism and Cardiovascular Risk in HIV-1 Infection and HAART: Present and Future Problems.
Journal: Cholesterol 20100101
Title: Raltegravir in combination with other antiretroviral agents for the treatment of HIV infection.
Journal: Infection and drug resistance 20100101
Title: Optimizing management of treatment-naïve and treatment-experienced HIV+ patients: the role of maraviroc.
Journal: HIV/AIDS (Auckland, N.Z.) 20100101
Title: Role of etravirine in the management of treatment-experienced patients with human immunodeficiency virus type 1.
Journal: HIV/AIDS (Auckland, N.Z.) 20100101
Title: Profile of maraviroc: a CCR5 antagonist in the management of treatment-experienced HIV patients.
Journal: HIV/AIDS (Auckland, N.Z.) 20100101
Title: Canadian consensus guidelines for the optimal use of maraviroc in the treatment of HIV-infected adults.
Journal: The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale 20100101
Title: Towards Inhibition of Vif-APOBEC3G Interaction: Which Protein to Target?
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Title: HTS and hit finding in academia--from chemical genomics to drug discovery.
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Title: Satisfactory cross-cultural validity of the ACTG symptom distress module in HIV-1-infected antiretroviral-naive patients.
Journal: Clinical trials (London, England) 20091201
Title: Antiretroviral therapy: new drugs, formulations, ideas, and strategies.
Journal: Topics in HIV medicine : a publication of the International AIDS Society, USA 20091201
Title: When and how to use maraviroc in HIV-infected patients.
Journal: AIDS (London, England) 20091127
Title: Cerebrospinal fluid maraviroc concentrations in HIV-1 infected patients.
Journal: AIDS (London, England) 20091127
Title: Is maraviroc beneficial in paradoxical progressive multifocal leukoencephalopathy-immune reconstitution inflammatory syndrome management?
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Title: [Features and the method of application of a CCR5 antagonist, a new integrase inhibitor].
Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20091110
Title: Adaptive mutations in a human immunodeficiency virus type 1 envelope protein with a truncated V3 loop restore function by improving interactions with CD4.
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Title: Efavirenz: a decade of clinical experience in the treatment of HIV.
Journal: The Journal of antimicrobial chemotherapy 20091101
Title: Maraviroc and raltegravir.
Journal: British journal of clinical pharmacology 20091101
Title: FDA advisory committee approves Selzentry.
Journal: AIDS patient care and STDs 20091101
Title: Novel drug classes: entry inhibitors [enfuvirtide, chemokine (C-C motif) receptor 5 antagonists].
Journal: Current opinion in HIV and AIDS 20091101
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20091101
Title: Correlation between the Trofile test and virological response to a short-term maraviroc exposure in HIV-infected patients.
Journal: The Journal of antimicrobial chemotherapy 20091001
Title: New antiretroviral drugs: a review of the efficacy, safety, pharmacokinetics, and resistance profile of tipranavir, darunavir, etravirine, rilpivirine, maraviroc, and raltegravir.
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Title: A liquid chromatography-tandem mass spectrometry assay for quantification of nevirapine, indinavir, atazanavir, amprenavir, saquinavir, ritonavir, lopinavir, efavirenz, tipranavir, darunavir and maraviroc in the plasma of patients infected with HIV.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091001
Title: Impact of adding maraviroc to antiretroviral regimens in patients with full viral suppression but impaired CD4 recovery.
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Title: Planning Future Strategies for Domestic and International NeuroAIDS Research, July 24-25, 2008.
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Title: CD4-BFFI: a novel, bifunctional HIV-1 entry inhibitor with high and broad antiviral potency.
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Title: New developments in HIV drug resistance.
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Title: The history of antiretrovirals: key discoveries over the past 25 years.
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Title: Maraviroc modelling strategy: use of early phase 1 data to support a semi-mechanistic population pharmacokinetic model.
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Title: [Immunorecovery after prolonged HIV-related immunosuppression: opportunities of the new antiretroviral classes].
Journal: Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 20090901
Title: Maraviroc concentrates in the cervicovaginal fluid and vaginal tissue of HIV-negative women.
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Title: Human immunodeficiency virus: 25 years of diagnostic and therapeutic strategies and their impact on hepatitis B and C virus.
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Title: Accelerated immunodeficiency by anti-CCR5 treatment in HIV infection.
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Title: Two HIV-1 variants resistant to small molecule CCR5 inhibitors differ in how they use CCR5 for entry.
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Title: 96-Week MERIT ES analysis shows efficacy of Celsentri=Selzentry.
Journal: AIDS patient care and STDs 20090801
Title: Concurrent use of statins does not influence efficacy of maraviroc in Maraviroc versus Optimized Therapy in Viremic Antiretroviral Treatment-Experienced Patients 1 and 2 trials.
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Title: Side chain flexibilities in the human ether-a-go-go related gene potassium channel (hERG) together with matched-pair binding studies suggest a new binding mode for channel blockers.
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Title: Rapamycin enhances aplaviroc anti-HIV activity: implications for the clinical development of novel CCR5 antagonists.
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Title: Detection of low-frequency pretherapy chemokine (CXC motif) receptor 4 (CXCR4)-using HIV-1 with ultra-deep pyrosequencing.
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Title: Maraviroc: perspectives for use in antiretroviral-naive HIV-1-infected patients.
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Title: A double-blind, placebo-controlled trial of maraviroc in treatment-experienced patients infected with non-R5 HIV-1.
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Title: Etravirine: new drug. Multidrug-resistant HIV: another option.
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Title: Gateways to clinical trials.
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Title: The transport of anti-HIV drugs across blood-CNS interfaces: summary of current knowledge and recommendations for further research.
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