Catalog No.:AA003VAJ

37762-06-4 | 5-(2-Propoxyphenyl)-1H-[1,2,3]triazolo[4,5-d]pyrimidin-7(4H)-one

Name: Name:5-(2-Propoxyphenyl)-1H-[1,2,3]triazolo[4,5-d]pyrimidin-7(4H)-one
Brand: AABLOCKS
SKU: AA003VAJ
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Rating: 90 (10 reviews)

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10mg

≥98%

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$40.00 $28.00

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50mg

≥98%

in stock

$168.00 $117.00

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100mg

≥98%

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$296.00 $207.00

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250mg

≥98%

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$640.00 $448.00

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Technical Information
Properties
Literature
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Technical Information
Properties
Literature

Technical Information

Catalog Number:

AA003VAJ

Chemical Name:

5-(2-Propoxyphenyl)-1H-[1,2,3]triazolo[4,5-d]pyrimidin-7(4H)-one

CAS Number:

37762-06-4

Molecular Formula:

C13H13N5O2

Molecular Weight:

271.2746

MDL Number:

MFCD00214073

SMILES:

CCCOc1ccccc1c1nc(=O)c2c([nH]1)nn[nH]2

NSC Number:

757885

Properties

Form:

Solid

MP:

229-233°C (dec.)

Storage:

-20 ℃;

Computed Properties

Complexity:

400

Covalently-Bonded Unit Count:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Rotatable Bond Count:

XLogP3:

1.6

Literature

Title: Choi SH , et al. Zaprinast, an inhibitor of cGMP-selective phosphodiesterases, enhances the secretion of TNF-alpha and IL-1beta and the expression of iNOS and MHC class II molecules in rat microglial cells. J Neurosci Res. 2002 Feb 1;67(3):411-21.

Title: Taniguchi Y, et al. Zaprinast, a well-known cyclic guanosine monophosphate-specific phosphodiesterase inhibitor, is an agonist for GPR35. FEBS Lett. 2006 Sep 18;580(21):5003-8. Epub 2006 Aug 17.

Title: Keswani AN , et al The cyclic GMP modulators YC-1 and zaprinast reduce vessel remodeling through antiproliferative and proapoptotic effects. J Cardiovasc Pharmacol Ther. 2009 Jun;14(2):116-24.

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