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38966-21-1,MFCD00083214
Catalog No.:AA00770A

38966-21-1 | 8,11|á-Methano-11aH-cyclohepta[a]naphthalene-4,9-dimethanol,tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-, (3R,4R,4aR,6aS,8R,9R,11aS,11bS)-

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1mg
≥98%
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$123.00   $86.00
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5mg
≥98%
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$392.00   $274.00
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25mg
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00770A
Chemical Name:
8,11|á-Methano-11aH-cyclohepta[a]naphthalene-4,9-dimethanol,tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-, (3R,4R,4aR,6aS,8R,9R,11aS,11bS)-
CAS Number:
38966-21-1
Molecular Formula:
C20H34O4
Molecular Weight:
338.4816
MDL Number:
MFCD00083214
SMILES:
OCC1(O)CCC23CC1CC2CCC1C3(C)CCC(C1(C)CO)O
Properties
Computed Properties
 
Complexity:
524  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
8  
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
2  
XLogP3:
2.5  

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Title: Breakages at common fragile sites set boundaries of amplified regions in two leukemia cell lines K562 - Molecular characterization of FRA2H and localization of a new CFS FRA2S.

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Title: Replication dynamics at common fragile site FRA6E.

Journal: Chromosoma 20101201

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Journal: Cancer letters 20101128

Title: Heterocellular induction of interferon by negative-sense RNA viruses.

Journal: Virology 20101125

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Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Replication-dependent γ-H2AX formation is involved in docetaxel-induced apoptosis in NSCLC A549 cells.

Journal: Oncology reports 20101101

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Journal: Chemical & pharmaceutical bulletin 20101101

Title: The Gag cleavage product, p12, is a functional constituent of the murine leukemia virus pre-integration complex.

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Journal: Molecular microbiology 20101001

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Journal: International journal of pharmaceutics 20100915

Title: Chemotherapy-induced genotoxic stress promotes sensitivity to natural killer cell cytotoxicity by enabling missing-self recognition.

Journal: Cancer research 20100915

Title: Synthesis of substituted thieno[2,3-d]pyrimidine-2,4-dithiones and their S-glycoside analogues as potential antiviral and antibacterial agents.

Journal: European journal of medicinal chemistry 20100901

Title: Preferential re-replication of Drosophila heterochromatin in the absence of geminin.

Journal: PLoS genetics 20100901

Title: Cyclin-dependent kinase activity controls the onset of the HCMV lytic cycle.

Journal: PLoS pathogens 20100901

Title: A key commitment step in erythropoiesis is synchronized with the cell cycle clock through mutual inhibition between PU.1 and S-phase progression.

Journal: PLoS biology 20100901

Title: The human genome puzzle - the role of copy number variation in somatic mosaicism.

Journal: Current genomics 20100901

Title: Genomic and epigenomic instability, fragile sites, schizophrenia and autism.

Journal: Current genomics 20100901

Title: ANO1 amplification and expression in HNSCC with a high propensity for future distant metastasis and its functions in HNSCC cell lines.

Journal: British journal of cancer 20100824

Title: Measurement of kinetic parameters of human platelet DNA polymerase gamma.

Journal: Methods (San Diego, Calif.) 20100801

Title: PSI-7851, a pronucleotide of beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine monophosphate, is a potent and pan-genotype inhibitor of hepatitis C virus replication.

Journal: Antimicrobial agents and chemotherapy 20100801

Title: Regulation of the PML tumor suppressor in drug-induced senescence of human normal and cancer cells by JAK/STAT-mediated signaling.

Journal: Cell cycle (Georgetown, Tex.) 20100801

Title: A nuclear family A DNA polymerase from Entamoeba histolytica bypasses thymine glycol.

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Title: Metabolites from the fungus Phoma sp. 7210, associated with Aizoon canariense.

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Title: DNA instability at chromosomal fragile sites in cancer.

Journal: Current genomics 20100801

Title: Mechanisms of genomic instabilities underlying two common fragile-site-associated loci, PARK2 and DMD, in germ cell and cancer cell lines.

Journal: American journal of human genetics 20100709

Title: Residue 752 in DNA polymerase of equine herpesvirus type 1 is non-essential for virus growth in vitro.

Journal: The Journal of general virology 20100701

Title: Strain variation in early innate cytokine induction by Plasmodium falciparum.

Journal: Parasite immunology 20100701

Title: TOPO3alpha influences antigenic variation by monitoring expression-site-associated VSG switching in Trypanosoma brucei.

Journal: PLoS pathogens 20100701

Title: Inhibition of topoisomerase I prevents chromosome breakage at common fragile sites.

Journal: DNA repair 20100604

Title: Supporting cell division is not required for regeneration of auditory hair cells after ototoxic injury in vitro.

Journal: Journal of the Association for Research in Otolaryngology : JARO 20100601

Title: Compounds that target host cell proteins prevent varicella-zoster virus replication in culture, ex vivo, and in SCID-Hu mice.

Journal: Antiviral research 20100601

Title: A strand invasion 3' polymerization intermediate of mammalian homologous recombination.

Journal: Genetics 20100601

Title: Nuclear localisation of LASP-1 correlates with poor long-term survival in female breast cancer.

Journal: British journal of cancer 20100525

Title: Inhibition of HIV-1 replication by isoxazolidine and isoxazole sulfonamides.

Journal: Chemical biology & drug design 20100501

Title: Inhibitory effects of diacylglyceride phospholipids on DNA polymerase and topoisomerase activities, and human cancer cell growth.

Journal: Medicinal chemistry (Shariqah (United Arab Emirates)) 20100501

Title: HIV Nuclear Entry: Clearing the Fog.

Journal: Viruses 20100501

Title: DNA breaks at fragile sites generate oncogenic RET/PTC rearrangements in human thyroid cells.

Journal: Oncogene 20100415

Title: Neuronal models for evaluation of proliferation in vitro using high content screening.

Journal: Toxicology 20100411

Title: Partitioning of histone H3-H4 tetramers during DNA replication-dependent chromatin assembly.

Journal: Science (New York, N.Y.) 20100402

Title: ATR preferentially interacts with common fragile site FRA3B and the binding requires its kinase activity in response to aphidicolin treatment.

Journal: Mutation research 20100401

Title: Low-copy repeats on chromosome 22q11.2 show replication timing switches, DNA flexibility peaks and stress inducible asynchrony, sharing instability features with fragile sites.

Journal: Mutation research 20100401

Title: Global screening and extended nomenclature for 230 aphidicolin-inducible fragile sites, including 61 yet unreported ones.

Journal: International journal of oncology 20100401

Title: Human polymerase alpha inhibitors for skin tumors. Part 2. Modeling, synthesis and influence on normal and transformed keratinocytes of new thymidine and purine derivatives.

Journal: Journal of enzyme inhibition and medicinal chemistry 20100401

Title: Replication timing of human telomeres is chromosome arm-specific, influenced by subtelomeric structures and connected to nuclear localization.

Journal: PLoS genetics 20100401

Title: The design and development of 2-aryl-2-hydroxy ethylamine substituted 1H,7H-pyrido[1,2,3-de]quinoxaline-6-carboxamides as inhibitors of human cytomegalovirus polymerase.

Journal: Bioorganic & medicinal chemistry letters 20100315

Title: Stereoselective synthesis and antiviral activity of (1E,2Z,3E)-1-(piperidin-1-yl)-1-(arylhydrazono)-2-[(benzoyl/benzothiazol-2-oyl)hydrazono]-4-(aryl(1))but-3-enes.

Journal: Archiv der Pharmazie 20100301

Title: Sceptrin, a marine natural compound, inhibits cell motility in a variety of cancer cell lines.

Journal: ACS chemical biology 20100219

Title: Giardia intestinalis: aphidicolin influence on the trophozoite cell cycle.

Journal: Experimental parasitology 20100201

Title: New aspects on chromosomal instability: chromosomal break-points in Fanconi anemia patients co-localize on the molecular level with fragile sites.

Journal: International journal of oncology 20100201

Title: Cytokine expression and signaling in drug-induced cellular senescence.

Journal: Oncogene 20100114

Title: Differential expression of a novel gene BRE (TNFRSF1A modulator/BRCC45) in response to stress and biological signals.

Journal: Molecular biology reports 20100101

Title: Impaired replication dynamics at the FRA3B common fragile site.

Journal: Human molecular genetics 20100101

Title: An aphidicolin-block nucleotide excision repair assay measuring DNA incision and repair capacity.

Journal: Mutagenesis 20100101

Title: Interferon-inducible IFI16, a negative regulator of cell growth, down-regulates expression of human telomerase reverse transcriptase (hTERT) gene.

Journal: PloS one 20100101

Title: The MCM-binding protein ETG1 aids sister chromatid cohesion required for postreplicative homologous recombination repair.

Journal: PLoS genetics 20100101

Title: Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons.

Journal: PLoS biology 20100101

Title: Unscheduled expression of CDC25B in S-phase leads to replicative stress and DNA damage.

Journal: Molecular cancer 20100101

Title: DNA-PKcs plays a dominant role in the regulation of H2AX phosphorylation in response to DNA damage and cell cycle progression.

Journal: BMC molecular biology 20100101

Title: Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway.

Journal: Molecular cancer 20100101

Title: Early embryonic chromosome instability results in stable mosaic pattern in human tissues.

Journal: PloS one 20100101

Title: Identification of four Entamoeba histolytica organellar DNA polymerases of the family B and cellular localization of the Ehodp1 gene and EhODP1 protein.

Journal: Journal of biomedicine & biotechnology 20100101

Title: Polo-like kinase 2-dependent phosphorylation of NPM/B23 on serine 4 triggers centriole duplication.

Journal: PloS one 20100101

Title: The onconeural antigen cdr2 is a novel APC/C target that acts in mitosis to regulate c-myc target genes in mammalian tumor cells.

Journal: PloS one 20100101

Title: Cytometry of chromatin bound Mcm6 and PCNA identifies two states in G1 that are separated functionally by the G1 restriction point.

Journal: BMC cell biology 20100101

Title: Cell cycle progression or translation control is not essential for vesicular stomatitis virus oncolysis of hepatocellular carcinoma.

Journal: PloS one 20100101

Title: Cell cycle and anti-estrogen effects synergize to regulate cell proliferation and ER target gene expression.

Journal: PloS one 20100101

Title: The effect of a DNA damaging agent on embryonic cell cycles of the cnidarian Hydractinia echinata.

Journal: PloS one 20100101

Title: Simultaneous visualization of FISH signals and bromo-deoxyuridine incorporation by formamide-free DNA denaturation.

Journal: Methods in molecular biology (Clifton, N.J.) 20100101

Title: Increased expression of bcl11b leads to chemoresistance accompanied by G1 accumulation.

Journal: PloS one 20100101

Title: Differential Dynamics of ATR-Mediated Checkpoint Regulators.

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Title: Somatic structural rearrangements in genetically engineered mouse mammary tumors.

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Title: Global analysis of the eukaryotic pathways and networks regulated by Salmonella typhimurium in mouse intestinal infection in vivo.

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Title: The normal development of Platynereis dumerilii (Nereididae, Annelida).

Journal: Frontiers in zoology 20100101

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Journal: The EMBO journal 20091202

Title: Common fragile sites are characterized by histone hypoacetylation.

Journal: Human molecular genetics 20091201

Title: Claspin inhibition leads to fragile site expression.

Journal: Genes, chromosomes & cancer 20091201

Title: Mechanism of DNA replication-dependent transcriptional activation of the acetylcholinesterase gene in the Ciona intestinalis embryo.

Journal: Development, growth & differentiation 20091201

Title: 3-O-methylfunicone, a selective inhibitor of mammalian Y-family DNA polymerases from an Australian sea salt fungal strain.

Journal: Marine drugs 20091201

Title: ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2.

Journal: The EMBO journal 20091104

Title: The Arabidopsis ATRIP ortholog is required for a programmed response to replication inhibitors.

Journal: The Plant journal : for cell and molecular biology 20091101

Title: Single-nucleotide and long-patch base excision repair of DNA damage in plants.

Journal: The Plant journal : for cell and molecular biology 20091101

Title: Identification of potent chemotypes targeting Leishmania major using a high-throughput, low-stringency, computationally enhanced, small molecule screen.

Journal: PLoS neglected tropical diseases 20091101

Title: MAP kinase dependent cyclinE/cdk2 activity promotes DNA replication in early sea urchin embryos.

Journal: Developmental biology 20091015

Title: Proteasome-dependent processing of topoisomerase I-DNA adducts into DNA double strand breaks at arrested replication forks.

Journal: The Journal of biological chemistry 20091009

Title: Dyslipidemia-induced neuropathy in mice: the role of oxLDL/LOX-1.

Journal: Diabetes 20091001

Title: Temporal differences in DNA replication during the S phase using single fiber analysis of normal human fibroblasts and glioblastoma T98G cells.

Journal: Cell cycle (Georgetown, Tex.) 20091001

Title: HIV-1 Vpr triggers natural killer cell-mediated lysis of infected cells through activation of the ATR-mediated DNA damage response.

Journal: PLoS pathogens 20091001

Title: Divergent S phase checkpoint activation arising from prereplicative complex deficiency controls cell survival.

Journal: Molecular biology of the cell 20090901

Title: Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice.

Journal: Genes & development 20090901

Title: Paternal effect of the nuclear formin-like protein MISFIT on Plasmodium development in the mosquito vector.

Journal: PLoS pathogens 20090801

Title: A link among DNA replication, recombination, and gene expression revealed by genetic and genomic analysis of TEBICHI gene of Arabidopsis thaliana.

Journal: PLoS genetics 20090801

Title: Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication.

Journal: Cell 20090710

Title: Artemis regulates cell cycle recovery from the S phase checkpoint by promoting degradation of cyclin E.

Journal: The Journal of biological chemistry 20090703

Title: A single-nucleotide polymorphism in a herpesvirus DNA polymerase is sufficient to cause lethal neurological disease.

Journal: The Journal of infectious diseases 20090701

Title: Inefficient double-strand DNA break repair is associated with increased fasciation in Arabidopsis BRCA2 mutants.

Journal: Journal of experimental botany 20090701

Title: Induction of glutathione-dependent DNA double-strand breaks by the novel anticancer drug brostallicin.

Journal: Molecular cancer therapeutics 20090701

Title: Temporal Notch activation through Notch1a and Notch3 is required for maintaining zebrafish rhombomere boundaries.

Journal: Development genes and evolution 20090701

Title: Chk1 C-terminal regulatory phosphorylation mediates checkpoint activation by de-repression of Chk1 catalytic activity.

Journal: Oncogene 20090618

Title: Interfering with Wnt signalling alters the periodicity of the segmentation clock.

Journal: Developmental biology 20090601

Title: The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities.

Journal: Nature cell biology 20090601

Title: Proteasome regulation of ULBP1 transcription.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20090515

Title: Inappropriate activation of cyclin-dependent kinases by the phosphatase Cdc25b results in premature mitotic entry and triggers a p53-dependent checkpoint.

Journal: The Journal of biological chemistry 20090403

Title: Inter-cellular variation in DNA content of Entamoeba histolytica originates from temporal and spatial uncoupling of cytokinesis from the nuclear cycle.

Journal: PLoS neglected tropical diseases 20090401

Title: Replication stress induces genome-wide copy number changes in human cells that resemble polymorphic and pathogenic variants.

Journal: American journal of human genetics 20090313

Title: Cell volume distributions reveal cell growth rates and division times.

Journal: Journal of theoretical biology 20090307

Title: Organization of human replicon: singles or zipping couples?

Journal: Journal of structural biology 20090301

Title: The activity of extracellular signal-regulated kinase is required during G2/M phase before metaphase-anaphase transition in synchronized leukemia cell lines.

Journal: International journal of hematology 20090301

Title: Mitotic recombination: why? when? how? where?

Journal: PLoS genetics 20090301

Title: Delineating metamorphic pathways in the ascidian Ciona intestinalis.

Journal: Developmental biology 20090215

Title: DNA replication arrest in response to genotoxic stress provokes early activation of stress-activated protein kinases (SAPK/JNK).

Journal: Journal of molecular biology 20090206

Title: Rapid DNA double-strand breaks resulting from processing of Cr-DNA cross-links by both MutS dimers.

Journal: Cancer research 20090201

Title: Establishment of human papillomavirus infection requires cell cycle progression.

Journal: PLoS pathogens 20090201

Title: Indirect participation of Hsp90 in the regulation of the cyclin E turnover.

Journal: Biochemical pharmacology 20090115

Title: An isoform of myosin XI is responsible for the translocation of endoplasmic reticulum in tobacco cultured BY-2 cells.

Journal: Journal of experimental botany 20090101

Title: Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogue.

Journal: BMC chemical biology 20090101

Title: Enhancing the efficacy of cisplatin in ovarian cancer treatment - could arsenic have a role.

Journal: Journal of ovarian research 20090101

Title: HIV-1 exploits importin 7 to maximize nuclear import of its DNA genome.

Journal: Retrovirology 20090101

Title: Simultaneous detection of FISH signals and bromo-deoxyuridine incorporation in fixed tissue cultured cells.

Journal: PloS one 20090101

Title: Impaired replication stress response in cells from immunodeficiency patients carrying Cernunnos/XLF mutations.

Journal: PloS one 20090101

Title: HAC stability in murine cells is influenced by nuclear localization and chromatin organization.

Journal: BMC cell biology 20090101

Title: Silencing of PINK1 expression affects mitochondrial DNA and oxidative phosphorylation in dopaminergic cells.

Journal: PloS one 20090101

Title: Skeletal muscle differentiation evokes endogenous XIAP to restrict the apoptotic pathway.

Journal: PloS one 20090101

Title: Proteins of the origin recognition complex (ORC) and DNA topoisomerases on mammalian chromatin.

Journal: BMC molecular biology 20090101

Title: Regulation of chk1.

Journal: Cell division 20090101

Title: Combining the receptor tyrosine kinase inhibitor AEE788 and the mammalian target of rapamycin (mTOR) inhibitor RAD001 strongly inhibits adhesion and growth of renal cell carcinoma cells.

Journal: BMC cancer 20090101

Title: Regulation of slow and fast muscle myofibrillogenesis by Wnt/beta-catenin and myostatin signaling.

Journal: PloS one 20090101

Title: Replication independent formation of extrachromosomal circular DNA in mammalian cell-free system.

Journal: PloS one 20090101

Title: Regulation of DNA replication by the S-phase DNA damage checkpoint.

Journal: Cell division 20090101

Title: Regulation of mitotic spindle formation by the RhoA guanine nucleotide exchange factor ARHGEF10.

Journal: BMC cell biology 20090101

Title: The cellular phenotype of Roberts syndrome fibroblasts as revealed by ectopic expression of ESCO2.

Journal: PloS one 20090101

Title: Comparative modeling of DNA and RNA polymerases from Moniliophthora perniciosa mitochondrial plasmid.

Journal: Theoretical biology & medical modelling 20090101

Title: Combination of interferon-alpha and 5-fluorouracil inhibits endothelial cell growth directly and by regulation of angiogenic factors released by tumor cells.

Journal: BMC cancer 20090101

Title: Inhibition of HIV-1 integrase nuclear import and replication by a peptide bearing integrase putative nuclear localization signal.

Journal: Retrovirology 20090101

Title: Cell cycle-dependent regulation of extra-adrenal glucocorticoid synthesis in murine intestinal epithelial cells.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20081201

Title: Fanconi anemia proteins stabilize replication forks.

Journal: DNA repair 20081201

Title: Cloning of Xenopus orthologs of Ctf7/Eco1 acetyltransferase and initial characterization of XEco2.

Journal: The FEBS journal 20081201

Title: Effect of dehydroaltenusin-C12 derivative, a selective DNA polymerase alpha inhibitor, on DNA replication in cultured cells.

Journal: Molecules (Basel, Switzerland) 20081201

Title: Increased coherence of circadian rhythms in mature fibroblast cultures.

Journal: Journal of biological rhythms 20081201

Title: Replication-dependent radiosensitization of human glioma cells by inhibition of poly(ADP-Ribose) polymerase: mechanisms and therapeutic potential.

Journal: International journal of radiation oncology, biology, physics 20081115

Title: A high-throughput and single-tube recombination of crude PCR products using a DNA polymerase inhibitor and type IIS restriction enzyme.

Journal: Journal of biotechnology 20081010

Title: Roles of the first and second round of DNA replication in the regulation of zygotic gene activation in mice.

Journal: The Journal of reproduction and development 20081001

Title: PP4 is a gamma H2AX phosphatase required for recovery from the DNA damage checkpoint.

Journal: EMBO reports 20081001

Title: Potential anti-respiratory syncytial virus lead compounds from Aglaia species.

Journal: Die Pharmazie 20081001

Title: Constitutive overexpression of CDC25A in primary human mammary epithelial cells results in both defective DNA damage response and chromosomal breaks at fragile sites.

Journal: International journal of cancer 20080915

Title: Roles of cyclins A and E in induction of centrosome amplification in p53-compromised cells.

Journal: Oncogene 20080911

Title: Tumor hypoxia: Impact on gene amplification in glioblastoma.

Journal: International journal of oncology 20080901

Title: Enhanced neurogenesis from neural progenitor cells with G1/S-phase cell cycle arrest is mediated by transforming growth factor beta1.

Journal: The European journal of neuroscience 20080901

Title: Cardiac differentiation in Xenopus requires the cyclin-dependent kinase inhibitor, p27Xic1.

Journal: Cardiovascular research 20080801

Title: Induction of a pro-apoptotic ATM-NF-kappaB pathway and its repression by ATR in response to replication stress.

Journal: The EMBO journal 20080723

Title: Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity.

Journal: The EMBO journal 20080723

Title: Multiple cellular mechanisms related to cyclin A1 in prostate cancer invasion and metastasis.

Journal: Journal of the National Cancer Institute 20080716

Title: Synthesis of 4-oxo-4,7-dihydrofuro[2,3-b]pyridine-5-carboxamides with broad-spectrum human herpesvirus polymerase inhibition.

Journal: Bioorganic & medicinal chemistry letters 20080715

Title: Synchronisation of Giardia lamblia: identification of cell cycle stage-specific genes and a differentiation restriction point.

Journal: International journal for parasitology 20080701

Title: Effect of serum starvation and chemical inhibitors on cell cycle synchronization of canine dermal fibroblasts.

Journal: Theriogenology 20080701

Title: Induction of the human heat shock promoter HSP70B by nutritional stress: implications for cancer gene therapy.

Journal: Cancer investigation 20080701

Title: Uncoupling the replication machinery: replication fork progression in the absence of processive DNA synthesis.

Journal: Cell cycle (Georgetown, Tex.) 20080701

Title: Differential association of Orc1 and Sir2 proteins to telomeric domains in Plasmodium falciparum.

Journal: Journal of cell science 20080615

Title: Metabolic interrelations within guanine deoxynucleotide pools for mitochondrial and nuclear DNA maintenance.

Journal: The Journal of biological chemistry 20080613

Title: The mammalian centrosome and its functional significance.

Journal: Histochemistry and cell biology 20080601

Title: Cell cycle dependent telomere regulation by telomerase in human bone marrow mesenchymal stem cells.

Journal: Biochemical and biophysical research communications 20080516

Title: PTIP/Swift is required for efficient PCNA ubiquitination in response to DNA damage.

Journal: DNA repair 20080503

Title: Haploinsufficiency of DNA Damage Response Genes and their Potential Influence in Human Genomic Disorders.

Journal: Current genomics 20080501

Title: Chk1 is activated at the midblastula transition in Xenopus laevis embryos independently of DNA content and the cyclin E/Cdk2 developmental timer.

Journal: Cell cycle (Georgetown, Tex.) 20080415

Title: Trans-generational radiation-induced chromosomal instability in the female enhances the action of chemical mutagens.

Journal: Mutation research 20080402

Title: Cell cycle synchrony in Giardia intestinalis cultures achieved by using nocodazole and aphidicolin.

Journal: Eukaryotic cell 20080401

Title: Anti proliferative activity of ELACY (CP-4055) in combination with cloretazine (VNP40101M), idarubicin, gemcitabine, irinotecan and topotecan in human leukemia and lymphoma cells.

Journal: Leukemia & lymphoma 20080401

Title: Plx1 is required for chromosomal DNA replication under stressful conditions.

Journal: The EMBO journal 20080319

Title: Targeting human DNA polymerase alpha for the inhibition of keratinocyte proliferation. Part 1. Homology model, active site architecture and ligand binding.

Journal: Journal of enzyme inhibition and medicinal chemistry 20080201

Title: Bloom's syndrome helicase and Mus81 are required to induce transient double-strand DNA breaks in response to DNA replication stress.

Journal: Journal of molecular biology 20080125

Title: Modulation of iridovirus-induced apoptosis by endocytosis, early expression, JNK, and apical caspase.

Journal: Virology 20080120

Title: Iridovirus Bcl-2 protein inhibits apoptosis in the early stage of viral infection.

Journal: Apoptosis : an international journal on programmed cell death 20080101

Title: Transcriptional analysis of a major capsid protein gene from Spodoptera exigua ascovirus 5a.

Journal: Archives of virology 20080101

Title: Human chromosome fragility.

Journal: Biochimica et biophysica acta 20080101

Title: HMGB1 protein inhibits DNA replication in vitro: a role of the acetylation and the acidic tail.

Journal: The international journal of biochemistry & cell biology 20080101

Title: Golgi cisternal unstacking stimulates COPI vesicle budding and protein transport.

Journal: PloS one 20080101

Title: Open-label comparative clinical study of chlorproguanil-dapsone fixed dose combination (Lapdap) alone or with three different doses of artesunate for uncomplicated Plasmodium falciparum malaria.

Journal: PloS one 20080101

Title: 14-3-3 theta binding to cell cycle regulatory factors is enhanced by HIV-1 Vpr.

Journal: Biology direct 20080101

Title: Chromosomal expression and localization of aphidicolin-induced fragile sites in the standard karyotype of river buffalo (Bubalus bubalis).

Journal: Cytogenetic and genome research 20080101

Title: 45S rDNA regions are chromosome fragile sites expressed as gaps in vitro on metaphase chromosomes of root-tip meristematic cells in Lolium spp.

Journal: PloS one 20080101

Title: Isolation and characterization of cidofovir resistant vaccinia viruses.

Journal: Virology journal 20080101

Title: Soluble histone H2AX is induced by DNA replication stress and sensitizes cells to undergo apoptosis.

Journal: Molecular cancer 20080101

Title: The effect of inhibited replication on DNA migration in the comet assay in relation to cytotoxicity and clastogenicity.

Journal: Mutation research 20080101

Title: A dynamic stochastic model for DNA replication initiation in early embryos.

Journal: PloS one 20080101

Title: High-fidelity correction of genomic uracil by human mismatch repair activities.

Journal: BMC molecular biology 20080101

Title: Combinative exposure effect of radio frequency signals from CDMA mobile phones and aphidicolin on DNA integrity.

Journal: Electromagnetic biology and medicine 20080101

Title: Identification of G1-regulated genes in normally cycling human cells.

Journal: PloS one 20080101

Title: Protective antiviral immunity conferred by a nonintegrative lentiviral vector-based vaccine.

Journal: PloS one 20080101

Title: DNA-activated protein kinase functions in a newly observed S phase checkpoint that links histone mRNA abundance with DNA replication.

Journal: The Journal of cell biology 20071231

Title: Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress.

Journal: Genes & development 20071215

Title: Susceptibility of Autographa californica multiple nucleopolyhedrovirus to inhibitors of DNA replication.

Journal: Journal of virological methods 20071201

Title: Expression of thymidylate synthase in human cells is an early G(1) event regulated by CDK4 and p16INK4A but not E2F.

Journal: British journal of cancer 20071105

Title: Novel aphidicolin-inducible common fragile site FRA9G maps to 9p22.2, within the C9orf39 gene.

Journal: Genes, chromosomes & cancer 20071101

Title: The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks.

Journal: Nature structural & molecular biology 20071101

Title: A point mutation in a herpesvirus polymerase determines neuropathogenicity.

Journal: PLoS pathogens 20071101

Title: Hyperspectral image analysis of live cells in various cell cycle stages.

Journal: Cell cycle (Georgetown, Tex.) 20071015

Title: Replication stress, defective S-phase checkpoint and increased death in Plk2-deficient human cancer cells.

Journal: Cell cycle (Georgetown, Tex.) 20071015

Title: The coupling of synthesis and partitioning of EBV's plasmid replicon is revealed in live cells.

Journal: The EMBO journal 20071003

Title: Cell cycle-and proteasome-dependent formation of etoposide-induced replication protein A (RPA) or Mre11/Rad50/Nbs1 (MRN) complex repair foci.

Journal: Cell cycle (Georgetown, Tex.) 20071001

Title: Cell cycle related modulations in Runx2 protein levels are independent of lymphocyte enhancer-binding factor 1 (Lef1) in proliferating osteoblasts.

Journal: Journal of molecular histology 20071001

Title: Evidence for direct involvement of the capsid protein in HIV infection of nondividing cells.

Journal: PLoS pathogens 20071001

Title: Nonclassic functions of human topoisomerase I: genome-wide and pharmacologic analyses.

Journal: Cancer research 20070915

Title: Paternal pronuclear DNA degradation is functionally linked to DNA replication in mouse oocytes.

Journal: Biology of reproduction 20070901

Title: Cytometry of ATM activation and histone H2AX phosphorylation to estimate extent of DNA damage induced by exogenous agents.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20070901

Title: H2AX foci in late S/G2- and M-phase cells after hydroxyurea- and aphidicolin-induced DNA replication stress in Vicia.

Journal: Histochemistry and cell biology 20070901

Title: Hydroxycarbamide in combination with azacitidine or decitabine is antagonistic on DNA methylation inhibition.

Journal: British journal of haematology 20070901

Title: Construction and biological activity of a full-length molecular clone of human Torque teno virus (TTV) genotype 6.

Journal: The FEBS journal 20070901

Title: Checkpoint adaptation in human cells.

Journal: Oncogene 20070830

Title: Buffalos (Bubalus bubalis) cloned by nuclear transfer of somatic cells.

Journal: Biology of reproduction 20070801

Title: Partial purification and characterization of DNA polymerase beta-like enzyme from Plasmodium falciparum.

Journal: Molecular and biochemical parasitology 20070801

Title: 7-Oxo-4,7-dihydrothieno[3,2-b]pyridine-6-carboxamides: synthesis and biological activity of a new class of highly potent inhibitors of human cytomegalovirus DNA polymerase.

Journal: Bioorganic & medicinal chemistry letters 20070715

Title: All beta cells contribute equally to islet growth and maintenance.

Journal: PLoS biology 20070701

Title: HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase.

Journal: PLoS pathogens 20070701

Title: 2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases.

Journal: Bioorganic & medicinal chemistry letters 20070615

Title: Cloning of genetically tagged chromosome break sequences reveals new fragile sites at 6p21 and 13q22.

Journal: International journal of cancer 20070601

Title: A novel DNA damage response: rapid degradation of the p12 subunit of dna polymerase delta.

Journal: The Journal of biological chemistry 20070525

Title: Influence of IBA and aphidicolin on DNA synthesis and adventitious root regeneration from Malus 'Jork 9' stem discs.

Journal: Plant cell reports 20070501

Title: Molecular characterization of the human common fragile site FRA1H.

Journal: Genes, chromosomes & cancer 20070501

Title: FRA18C: a new aphidicolin-inducible fragile site on chromosome 18q22, possibly associated with in vivo chromosome breakage.

Journal: Journal of medical genetics 20070501

Title: Effects of synchronization of donor cell cycle on embryonic development and DNA synthesis in porcine nuclear transfer embryos.

Journal: The Journal of reproduction and development 20070401

Title: Modified LDLs induce proliferation-mediated death of human vascular endothelial cells through MAPK pathway.

Journal: American journal of physiology. Heart and circulatory physiology 20070401

Title: S-phase checkpoints regulate Apo2 ligand/TRAIL and CPT-11-induced apoptosis of prostate cancer cells.

Journal: Molecular cancer therapeutics 20070401

Title: DNA-PK is involved in repairing a transient surge of DNA breaks induced by deceleration of DNA replication.

Journal: Journal of molecular biology 20070330

Title: Highly selective action of triphosphate metabolite of 4'-ethynyl D4T: a novel anti-HIV compound against HIV-1 RT.

Journal: Antiviral research 20070301

Title: Chromosome aberrations in Chinese hamster and human cells: a comparison using compounds with various genotoxicity profiles.

Journal: Mutation research 20070301

Title: Nanomedicines in renal transplant rejection--focus on sirolimus.

Journal: International journal of nanomedicine 20070301

Title: Irofulven induces replication-dependent CHK2 activation related to p53 status.

Journal: Biochemical pharmacology 20070215

Title: FRA1E common fragile site breaks map within a 370kilobase pair region and disrupt the dihydropyrimidine dehydrogenase gene (DPYD).

Journal: Cancer letters 20070208

Title: Osteopontin localizes to the nucleus of 293 cells and associates with polo-like kinase-1.

Journal: American journal of physiology. Cell physiology 20070201

Title: Onset of the DNA replication checkpoint in the early Drosophila embryo.

Journal: Genetics 20070201

Title: Determination of growth inhibitory action point of interferon gamma on WISH cells in cell cycle progression and the window of responsiveness of the cells to the interferon.

Journal: Cytokine 20070201

Title: A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice.

Journal: Nature genetics 20070101

Title: Ascorbate acts as a highly potent inducer of chromate mutagenesis and clastogenesis: linkage to DNA breaks in G2 phase by mismatch repair.

Journal: Nucleic acids research 20070101

Title: Arabidopsis WEE1 kinase controls cell cycle arrest in response to activation of the DNA integrity checkpoint.

Journal: The Plant cell 20070101

Title: Spontaneous unusual expression of frequency of chromosome aberrations and common fragile in human lymphocytes of colorectal cancer patients induced by Aphidicolin.

Journal: Journal of experimental therapeutics & oncology 20070101

Title: Rhodococcus fascians infection accelerates progression of tobacco BY-2 cells into mitosis through rapid changes in plant gene expression.

Journal: The New phytologist 20070101

Title: HIV-1 Vpr activates the G2 checkpoint through manipulation of the ubiquitin proteasome system.

Journal: Virology journal 20070101

Title: Transcriptome changes and cAMP oscillations in an archaeal cell cycle.

Journal: BMC cell biology 20070101

Title: Genome position and gene amplification.

Journal: Genome biology 20070101

Title: ATM activation accompanies histone H2AX phosphorylation in A549 cells upon exposure to tobacco smoke.

Journal: BMC cell biology 20070101

Title: Establishment and mitotic stability of an extra-chromosomal mammalian replicon.

Journal: BMC cell biology 20070101

Title: Molecular portrait of cisplatin induced response in human testis cancer cell lines based on gene expression profiles.

Journal: Molecular cancer 20070101

Title: Base excision repair of ionizing radiation-induced DNA damage in G1 and G2 cell cycle phases.

Journal: Cancer cell international 20070101

Title: Chromosomal instability in Afrotheria: fragile sites, evolutionary breakpoints and phylogenetic inference from genome sequence assemblies.

Journal: BMC evolutionary biology 20070101

Title: Differential intracellular distribution of DNA complexed with polyethylenimine (PEI) and PEI-polyarginine PTD influences exogenous gene expression within live COS-7 cells.

Journal: Genetic vaccines and therapy 20070101

Title: Role of the long cytoplasmic domain of the SIV Env glycoprotein in early and late stages of infection.

Journal: Retrovirology 20070101

Title: Fra-1 governs cell migration via modulation of CD44 expression in human mesotheliomas.

Journal: Molecular cancer 20070101

Title: Hereditary ataxia SCAN1 cells are defective for the repair of transcription-dependent topoisomerase I cleavage complexes.

Journal: DNA repair 20061209

Title: Induction of transcriptionally active Jun proteins regulates drug-induced senescence.

Journal: The Journal of biological chemistry 20061110

Title: Deregulated replication licensing causes DNA fragmentation consistent with head-to-tail fork collision.

Journal: Molecular cell 20061103

Title: Molecular cloning and gene expression of a fibrillarin homolog of tobacco BY-2 cells.

Journal: Protoplasma 20061101

Title: Monoubiquitination of proliferating cell nuclear antigen induced by stalled replication requires uncoupling of DNA polymerase and mini-chromosome maintenance helicase activities.

Journal: The Journal of biological chemistry 20061027

Title: Can individual repair kinetics of UVC-induced DNA damage in human lymphocytes be assessed through the comet assay?

Journal: Mutation research 20061010

Title: Temporal and differential gene expression of Singapore grouper iridovirus.

Journal: The Journal of general virology 20061001

Title: Cyclin A1/Cdk2 is sufficient but not required for the induction of apoptosis in early Xenopus laevis embryos.

Journal: Cell cycle (Georgetown, Tex.) 20061001

Title: tRNAs promote nuclear import of HIV-1 intracellular reverse transcription complexes.

Journal: PLoS biology 20061001

Title: A chemical genetic screen for cell cycle inhibitors in zebrafish embryos.

Journal: Chemical biology & drug design 20061001

Title: Timing the generation of distinct retinal cells by homeobox proteins.

Journal: PLoS biology 20060901

Title: Exit from arsenite-induced mitotic arrest is p53 dependent.

Journal: Environmental health perspectives 20060901

Title: Human DNA polymerase N (POLN) is a low fidelity enzyme capable of error-free bypass of 5S-thymine glycol.

Journal: The Journal of biological chemistry 20060818

Title: Construction of tricyclic enone, a common precursor for aphidicolane and stemodane B/C/D-ring system.

Journal: Chemical & pharmaceutical bulletin 20060801

Title: Depletion of CHK1, but not CHK2, induces chromosomal instability and breaks at common fragile sites.

Journal: Oncogene 20060727

Title: Regulation of Claspin degradation by the ubiquitin-proteosome pathway during the cell cycle and in response to ATR-dependent checkpoint activation.

Journal: FEBS letters 20060724

Title: Generation of replication-dependent double-strand breaks by the novel N2-G-alkylator S23906-1.

Journal: Cancer research 20060715

Title: Involvement of DNA replication in ultraviolet-induced apoptosis of mammalian cells.

Journal: Apoptosis : an international journal on programmed cell death 20060701

Title: Accumulation of FFA-1, the Xenopus homolog of Werner helicase, and DNA polymerase delta on chromatin in response to replication fork arrest.

Journal: Journal of biochemistry 20060701

Title: Sphere formation of ocular epithelial cells in the ciliary body is a reprogramming system for neural differentiation.

Journal: Brain research 20060606

Title: Synchronization in the cell cycle by inhibitors of DNA replication induces histone H2AX phosphorylation: an indication of DNA damage.

Journal: Cell proliferation 20060601

Title: Polyamine depletion and cell cycle manipulation in combination with HSV thymidine kinase/ganciclovir cancer gene therapy.

Journal: International journal of oncology 20060601

Title: A biological evaluation of DNA damage detected by comet assay in healthy populations residing in areas that differ in lung cancer incidence.

Journal: Journal of toxicology and environmental health. Part A 20060601

Title: P21Cip1/WAF1 downregulation is required for efficient PCNA ubiquitination after UV irradiation.

Journal: Oncogene 20060511

Title: p21CDKN1A allows the repair of replication-mediated DNA double-strand breaks induced by topoisomerase I and is inactivated by the checkpoint kinase inhibitor 7-hydroxystaurosporine.

Journal: Oncogene 20060511

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Involvement of 2-C-methyl-D-erythritol-4-phosphate pathway in biosynthesis of aphidicolin-like tetracyclic diterpene of Scoparia dulcis.

Journal: Chemical & pharmaceutical bulletin 20060501

Title: The D-type cyclin CYCD3;1 is limiting for the G1-to-S-phase transition in Arabidopsis.

Journal: The Plant cell 20060401

Title: Effects of hydroxyurea and aphidicolin on phosphorylation of ataxia telangiectasia mutated on Ser 1981 and histone H2AX on Ser 139 in relation to cell cycle phase and induction of apoptosis.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060401

Title: A simple, flexible, nonfluorescent system for the automated screening of neurite outgrowth.

Journal: Journal of biomolecular screening 20060301

Title: Localization of MCM2-7, Cdc45, and GINS to the site of DNA unwinding during eukaryotic DNA replication.

Journal: Molecular cell 20060217

Title: Distinguishing between linear and exponential cell growth during the division cycle: single-cell studies, cell-culture studies, and the object of cell-cycle research.

Journal: Theoretical biology & medical modelling 20060101

Title: Comparative genomic mapping of the bovine Fragile Histidine Triad (FHIT) tumour suppressor gene: characterization of a 2 Mb BAC contig covering the locus, complete annotation of the gene, analysis of cDNA and of physiological expression profiles.

Journal: BMC genomics 20060101

Title: Synchronization, transformation, and cryopreservation of suspension-cultured cells.

Journal: Methods in molecular biology (Clifton, N.J.) 20060101

Title: 'ATR activation in response to ionizing radiation: still ATM territory'.

Journal: Cell division 20060101

Title: Cdc45-MCM-GINS, a new power player for DNA replication.

Journal: Cell division 20060101

Title: Kinesin-5 motors are required for organization of spindle microtubules in Silvetia compressa zygotes.

Journal: BMC plant biology 20060101

Title: Correlated fragile site expression allows the identification of candidate fragile genes involved in immunity and associated with carcinogenesis.

Journal: BMC bioinformatics 20060101

Title: Deoxycytidine kinase is reversibly phosphorylated in normal human lymphocytes.

Journal: Nucleosides, nucleotides & nucleic acids 20060101

Title: HIV infection of non-dividing cells: a divisive problem.

Journal: Retrovirology 20060101

Title: Genome-wide sequence and functional analysis of early replicating DNA in normal human fibroblasts.

Journal: BMC genomics 20060101

Title: Is mammalian chromosomal evolution driven by regions of genome fragility?

Journal: Genome biology 20060101

Title: Regulated polyploidy in halophilic archaea.

Journal: PloS one 20060101

Title: Cell cycle synchronization of tobacco BY-2 cells.

Journal: Nature protocols 20060101

Title: Human mismatch repair: reconstitution of a nick-directed bidirectional reaction.

Journal: The Journal of biological chemistry 20051202

Title: Genomic sequence correction by single-stranded DNA oligonucleotides: role of DNA synthesis and chemical modifications of the oligonucleotide ends.

Journal: The journal of gene medicine 20051201

Title: Treatment with hydroxyurea and tyrphostin-1 significantly improves the transduction efficiency of recombinant adeno-associated viruses in human cancer cells.

Journal: Oncology reports 20051201

Title: Interactions between the cell cycle and embryonic patterning in Arabidopsis uncovered by a mutation in DNA polymerase epsilon.

Journal: The Plant cell 20051201

Title: Securin is not required for chromosomal stability in human cells.

Journal: PLoS biology 20051201

Title: Small molecules that delay S phase suppress a zebrafish bmyb mutant.

Journal: Nature chemical biology 20051201

Title: Origin and characterization of multipotential mesenchymal stem cells derived from adult human trabecular bone.

Journal: Stem cells and development 20051201

Title: Phosphodiesterase 3A binds to 14-3-3 proteins in response to PMA-induced phosphorylation of Ser428.

Journal: The Biochemical journal 20051115

Title: Nucleotide excision repair functions in the removal of chromium-induced DNA damage in mammalian cells.

Journal: Molecular and cellular biochemistry 20051101

Title: The cell cycle independence of HIV infections is not determined by known karyophilic viral elements.

Journal: PLoS pathogens 20051101

Title: Endothelial adhesion of synchronized gastric tumor cells changes during cell cycle transit and correlates with the expression level of CD44 splice variants.

Journal: World journal of gastroenterology 20051028

Title: Ku86 modulates DNA topoisomerase I-mediated radiosensitization, but not cytotoxicity, in mammalian cells.

Journal: Cancer research 20051015

Title: Exploiting PdII and TiIII chemistry to obtain gamma-dioxygenated terpenoids: synthesis of rostratone and novel approaches to aphidicolin and pyripyropene A.

Journal: The Journal of organic chemistry 20051014

Title: Potentiation of in vitro ara-C cytotoxicity by ribonucleotide reductase inhibitors, cyclin-dependent kinase modulators and the DNA repair inhibitor aphidicolin in paediatric acute myeloid leukaemia.

Journal: British journal of haematology 20051001

Title: Tobacco BY-2 cells expressing fission yeast cdc25 bypass a G2/M block on the cell cycle.

Journal: The Plant journal : for cell and molecular biology 20051001

Title: 4-Oxo-4,7-dihydrothieno[2,3-b]pyridines as non-nucleoside inhibitors of human cytomegalovirus and related herpesvirus polymerases.

Journal: Journal of medicinal chemistry 20050908

Title: Effects of abiotic stresses on cell cycle progression in tobacco BY-2 cells.

Journal: Molecules and cells 20050831

Title: The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor.

Journal: Nature 20050825

Title: Identification of molecular mechanisms for cellular drug resistance by combining drug activity and gene expression profiles.

Journal: British journal of cancer 20050822

Title: Analysis of tissue flow patterns during primitive streak formation in the chick embryo.

Journal: Developmental biology 20050801

Title: Hedamycin, a DNA alkylator, induces (gamma)H2AX and chromosome aberrations: involvement of phosphatidylinositol 3-kinase-related kinases and DNA replication fork movement.

Journal: Molecular cancer therapeutics 20050801

Title: Dependence of the timing system regulating the onset of gastrulation on cytoplasmic, but not nuclear, activities in the Xenopus embryo.

Journal: Development, growth & differentiation 20050801

Title: Inhibition of mammalian DNA polymerases by resveratrol: mechanism and structural determinants.

Journal: The Biochemical journal 20050715

Title: Caffeine inhibits callose deposition in the cell plate and the depolymerization of microtubules in the central region of the phragmoplast.

Journal: Plant & cell physiology 20050701

Title: Differences in the association of p53 phosphorylated on serine 15 and key enzymes of homologous recombination.

Journal: Oncogene 20050623

Title: DNA-protein cross-links and replication-dependent histone H2AX phosphorylation induced by aminoflavone (NSC 686288), a novel anticancer agent active against human breast cancer cells.

Journal: Cancer research 20050615

Title: DNA damage induced hyperphosphorylation of replication protein A. 1. Identification of novel sites of phosphorylation in response to DNA damage.

Journal: Biochemistry 20050614

Title: Beta-catenin cleavage in non-apoptotic cells with reduced cell adhesion activity.

Journal: International journal of molecular medicine 20050601

Title: Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint.

Journal: Genes & development 20050501

Title: Identification of four adenosine kinase isoforms in tobacco By-2 cells and their putative role in the cell cycle-regulated cytokinin metabolism.

Journal: The Journal of biological chemistry 20050429

Title: Cell size-dependent and independent proliferation of rodent neuroblastoma x glioma cells.

Journal: Journal of cellular physiology 20050401

Title: Assessment of human DNA repair (NER) capacity with DNA repair rate (DRR) by comet assay.

Journal: Biomedical and environmental sciences : BES 20050401

Title: erbb3 and erbb2 are essential for schwann cell migration and myelination in zebrafish.

Journal: Current biology : CB 20050329

Title: Hair cell regeneration in sensory epithelia from the inner ear of a urodele amphibian.

Journal: The Journal of comparative neurology 20050328

Title: Induction of fusion-competent myoblast-specific gene expression during myogenic differentiation of Drosophila Schneider cells by DNA double-strand breaks or replication inhibition.

Journal: Biochimica et biophysica acta 20050322

Title: Hypersensitivity in DNA mismatch repair-deficient colon carcinoma cells to DNA polymerase reaction inhibitors.

Journal: Cancer letters 20050318

Title: Assessment of DNA damage in peripheral blood of heavy smokers with the comet assay and the micronucleus test.

Journal: Mutation research 20050307

Title: The Fanconi anemia pathway is required for the DNA replication stress response and for the regulation of common fragile site stability.

Journal: Human molecular genetics 20050301

Title: Tissue-specific profile of DNA replication in the swimming larvae of Ciona intestinalis.

Journal: Zoological science 20050301

Title: SMC1 involvement in fragile site expression.

Journal: Human molecular genetics 20050215

Title: ERK1 activation is required for S-phase onset and cell cycle progression after fertilization in sea urchin embryos.

Journal: Development (Cambridge, England) 20050201

Title: Histone H2AX phosphorylation after cell irradiation with UV-B: relationship to cell cycle phase and induction of apoptosis.

Journal: Cell cycle (Georgetown, Tex.) 20050201

Title: SAS-6 defines a protein family required for centrosome duplication in C. elegans and in human cells.

Journal: Nature cell biology 20050201

Title: Alkene-arene meta photocycloadditions with a four-carbon-atom tether: efficient approach toward the polycyclic ring systems of aphidicolin and stemodinone.

Journal: Angewandte Chemie (International ed. in English) 20050128

Title: Using fluorescence for improvement of the quantitative analysis of micronucleus in cell culture.

Journal: Mutation research 20050103

Title: Evolutionary breakpoints are co-localized with fragile sites and intrachromosomal telomeric sequences in primates.

Journal: Cytogenetic and genome research 20050101

Title: Increased systemic efficacy of aphidicolin encapsulated in liposomes.

Journal: Oncology reports 20050101

Title: Endogenous cytokinin oscillations control cell cycle progression of tobacco BY-2 cells.

Journal: Plant biology (Stuttgart, Germany) 20050101

Title: The role of plasmid constructs containing the SV40 DNA nuclear-targeting sequence in cationic lipid-mediated DNA delivery.

Journal: Cellular & molecular biology letters 20050101

Title: Runx-dependent expression of PKC is critical for cell survival in the sea urchin embryo.

Journal: BMC biology 20050101

Title: Nick-directed repair of palindromic loop mismatches in human cell extracts.

Journal: Journal of biomedical science 20050101

Title: Contribution of the C-terminal tri-lysine regions of human immunodeficiency virus type 1 integrase for efficient reverse transcription and viral DNA nuclear import.

Journal: Retrovirology 20050101

Title: The effect of larval age on developmental changes in the polyp prepattern of a hydrozoan planula.

Journal: Zoology (Jena, Germany) 20050101

Title: [A study of chromosomal fragility in peripheral blood lymphocytes in patients with lymphomas].

Journal: Tsitologiia 20050101

Title: DNA ligand Hoechst-33342 enhances UV induced cytotoxicity in human glioma cell lines.

Journal: Journal of photochemistry and photobiology. B, Biology 20041202

Title: Characterization of a novel ATR-dependent, Chk1-independent, intra-S-phase checkpoint that suppresses initiation of replication in Xenopus.

Journal: Journal of cell science 20041201

Title: Enhancement of genotoxic effects in the comet assay with human blood samples by aphidicolin.

Journal: Toxicology letters 20041128

Title: Interaction between human MCM7 and Rad17 proteins is required for replication checkpoint signaling.

Journal: The EMBO journal 20041124

Title: Transition of G1 to early S phase may be required for zinnia mesophyll cells to trans-differentiate to tracheary elements.

Journal: Planta 20041101

Title: Fhit-deficient normal and cancer cells are mitomycin C and UVC resistant.

Journal: British journal of cancer 20041101

Title: Differential regulation of platelet-derived growth factor stimulated migration and proliferation in osteoblastic cells.

Journal: Journal of cellular biochemistry 20041101

Title: Chromosomal instability at common fragile sites in Seckel syndrome.

Journal: American journal of human genetics 20041001

Title: Crosstalk between elicitor-induced cell death and cell cycle regulation in tobacco BY-2 cells.

Journal: The Plant journal : for cell and molecular biology 20041001

Title: Cell-cycle dependence of foamy virus vectors.

Journal: The Journal of general virology 20041001

Title: A hypophosphorylated form of RPA34 is a specific component of pre-replication centers.

Journal: Journal of cell science 20041001

Title: Selective increase of dATP pools upon activation of deoxycytidine kinase in lymphocytes: implications in apoptosis.

Journal: Nucleosides, nucleotides & nucleic acids 20041001

Title: Stimulation of deoxycytidine kinase results in prolonged maintenance of the enzyme activity.

Journal: Nucleosides, nucleotides & nucleic acids 20041001

Title: A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication.

Journal: The EMBO journal 20040915

Title: Effects of gemcitabine on APE/ref-1 endonuclease activity in pancreatic cancer cells, and the therapeutic potential of antisense oligonucleotides.

Journal: British journal of cancer 20040913

Title: Characterization of a conserved aphidicolin-sensitive common fragile site at human 4q22 and mouse 6C1: possible association with an inherited disease and cancer.

Journal: Oncogene 20040909

Title: Purification of Drosophila DNA polymerase zeta by REV1 protein-affinity chromatography.

Journal: The Biochemical journal 20040901

Title: Identification of compounds that enhance the anti-lymphoma activity of rituximab using flow cytometric high-content screening.

Journal: Journal of immunological methods 20040901

Title: Frequent downregulation and loss of WWOX gene expression in human hepatocellular carcinoma.

Journal: British journal of cancer 20040816

Title: Jasmonic acid prevents the accumulation of cyclin B1;1 and CDK-B in synchronized tobacco BY-2 cells.

Journal: FEBS letters 20040813

Title: Dideoxynucleoside triphosphate-sensitive DNA polymerase from rice is involved in base excision repair and immunologically similar to mammalian DNA pol beta.

Journal: Biochemical and biophysical research communications 20040716

Title: Control of replication origin density and firing time in Xenopus egg extracts: role of a caffeine-sensitive, ATR-dependent checkpoint.

Journal: The Journal of biological chemistry 20040702

Title: Aphidicolin-resistant and -sensitive base excision repair in wild-type and DNA polymerase beta-defective mouse cells.

Journal: DNA repair 20040702

Title: Fibroblast growth factor-10 attenuates H2O2-induced alveolar epithelial cell DNA damage: role of MAPK activation and DNA repair.

Journal: American journal of respiratory cell and molecular biology 20040701

Title: The telomeric region is excluded from nucleosomal fragmentation during apoptosis, but the bulk nuclear chromatin is randomly degraded.

Journal: Cell death and differentiation 20040701

Title: Two breakpoint clusters at fragile site FRA3B form phased nucleosomes.

Journal: Genome research 20040701

Title: Synchronized generation of reactive oxygen species with the cell cycle.

Journal: Life sciences 20040604

Title: Bromodeoxyuridine DNA fiber technology in plants: replication origins and DNA synthesis in tobacco BY-2 cells under prolonged treatment with aphidicolin.

Journal: Protoplasma 20040601

Title: Adaptation of a DNA replication checkpoint response depends upon inactivation of Claspin by the Polo-like kinase.

Journal: Cell 20040528

Title: The anticancer drug mithramycin A sensitises tumour cells to apoptosis induced by tumour necrosis factor (TNF).

Journal: British journal of cancer 20040517

Title: ATR regulates a G2-phase cell-cycle checkpoint in Arabidopsis thaliana.

Journal: The Plant cell 20040501

Title: Bloodstream form-specific up-regulation of silent vsg expression sites and procyclin in Trypanosoma brucei after inhibition of DNA synthesis or DNA damage.

Journal: The Journal of biological chemistry 20040402

Title: [Detecting DNA repair capacity of human lymphocytes exposed to ultraviolet C with comet assay].

Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20040401

Title: An automated image capture and quantitation approach to identify proteins affecting tumor cell proliferation.

Journal: Journal of biomolecular screening 20040401

Title: Activation of deoxycytidine kinase in lymphocytes is calcium dependent and involves a conformational change detectable by native immunostaining.

Journal: Biochemical pharmacology 20040301

Title: Aphidicolin and bleomycin induced chromosome damage as biomarker of mutagen sensitivity: a twin study.

Journal: Mutation research 20040226

Title: The role of baculovirus apoptotic suppressors in AcMNPV-mediated translation arrest in Ld652Y cells.

Journal: Virology 20040220

Title: Characterization of DNA demethylation in normal and cancerous cell lines and the regulatory role of cell cycle proteins in human DNA demethylase activity.

Journal: Journal of cellular biochemistry 20040215

Title: Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: mechanism and therapeutic implications.

Journal: Cancer research 20040215

Title: Rb regulates C/EBPbeta-DNA-binding activity during 3T3-L1 adipogenesis.

Journal: American journal of physiology. Cell physiology 20040201

Title: RXRalpha mRNA expression is associated with cell proliferation and cell cycle regulation in Hep3B cell.

Journal: Experimental and molecular pathology 20040201

Title: PPARgamma1 synthesis and adipogenesis in C3H10T1/2 cells depends on S-phase progression, but does not require mitotic clonal expansion.

Journal: Journal of cellular biochemistry 20040201

Title: Efficient transfection of non-proliferating human airway epithelial cells with a synthetic vector system.

Journal: The journal of gene medicine 20040201

Title: The Yin Yang-1 (YY1) protein undergoes a DNA-replication-associated switch in localization from the cytoplasm to the nucleus at the onset of S phase.

Journal: Journal of cell science 20040126

Title: The role of late/slow replication of the FRA16D in common fragile site induction.

Journal: Genes, chromosomes & cancer 20040101

Title: In vivo analysis of cell division, cell growth, and differentiation at the shoot apical meristem in Arabidopsis.

Journal: The Plant cell 20040101

Title: Cloning of a gene cluster responsible for the biosynthesis of diterpene aphidicolin, a specific inhibitor of DNA polymerase alpha.

Journal: Bioscience, biotechnology, and biochemistry 20040101

Title: [A comparative level of expression of some proteins in XL2 cell synchronized on different phases of cell cycle].

Journal: Tsitologiia 20040101

Title: Functional analysis of APC-Cdh1.

Journal: Methods in molecular biology (Clifton, N.J.) 20040101

Title: Regulation of DNA replication by ATR: signaling in response to DNA intermediates.

Journal: DNA repair 20040101

Title: Halofuginone inhibits serum-stimulated pericardial tissue retraction in vitro.

Journal: Tissue engineering 20040101

Title: Control and maintenance of mammalian cell size.

Journal: BMC cell biology 20040101

Title: Control and maintenance of mammalian cell size: response.

Journal: BMC cell biology 20040101

Title: Conservation of aphidicolin-induced fragile sites in Papionini (Primates) species and humans.

Journal: Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 20040101

Title: [Special function of deoxycytidine kinase (dCK) in the activation of chemotherapeutic nucleoside analogs and in the inhibition of cell proliferation].

Journal: Magyar onkologia 20040101

Title: Size control in growing yeast and mammalian cells.

Journal: Theoretical biology & medical modelling 20040101

Title: Characterisation of cytotoxicity and DNA damage induced by the topoisomerase II-directed bisdioxopiperazine anti-cancer agent ICRF-187 (dexrazoxane) in yeast and mammalian cells.

Journal: BMC pharmacology 20040101

Title: Nick-dependent and -independent processing of large DNA loops in human cells.

Journal: The Journal of biological chemistry 20031212

Title: Investigations on the effect of cigarette smoking in the comet assay.

Journal: Mutation research 20031209

Title: Hypo-osmotic or Ca2+-rich external conditions trigger extra contractile vacuole complex generation in Paramecium multimicronucleatum.

Journal: The Journal of experimental biology 20031201

Title: Comparison of hypoxia-induced replication arrest with hydroxyurea and aphidicolin-induced arrest.

Journal: Mutation research 20031127

Title: Comparison of checkpoint responses triggered by DNA polymerase inhibition versus DNA damaging agents.

Journal: Mutation research 20031127

Title: Constitutive DNA damage is linked to DNA replication abnormalities in Bloom's syndrome cells.

Journal: Oncogene 20031127

Title: Replication inhibitors modulate instability of an expanded trinucleotide repeat at the myotonic dystrophy type 1 disease locus in human cells.

Journal: American journal of human genetics 20031101

Title: Genome-wide gene expression in an Arabidopsis cell suspension.

Journal: Plant molecular biology 20031101

Title: 8-Oxoguanine DNA damage: at the crossroad of alternative repair pathways.

Journal: Mutation research 20031029

Title: Xenopus Drf1, a regulator of Cdc7, displays checkpoint-dependent accumulation on chromatin during an S-phase arrest.

Journal: The Journal of biological chemistry 20031017

Title: The ORC1 cycle in human cells: I. cell cycle-regulated oscillation of human ORC1.

Journal: The Journal of biological chemistry 20031017

Title: The role of DNA synthesis inhibition in the cytotoxicity of 2',2'-difluoro-2'-deoxycytidine.

Journal: Cancer chemotherapy and pharmacology 20031001

Title: Flavopiridol potently induces small cell lung cancer apoptosis during S phase in a manner that involves early mitochondrial dysfunction.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20031001

Title: Suppression of Tousled-like kinase activity after DNA damage or replication block requires ATM, NBS1 and Chk1.

Journal: Oncogene 20030904

Title: Bovine BRCA1 shows classic responses to genotoxic stress but low in vitro transcriptional activation activity.

Journal: Oncogene 20030904

Title: XRad17 is required for the activation of XChk1 but not XCds1 during checkpoint signaling in Xenopus.

Journal: Molecular biology of the cell 20030901

Title: Origin of cortical microtubules organized at M/G1 interface: recruitment of tubulin from phragmoplast to nascent microtubules.

Journal: European journal of cell biology 20030901

Title: Characterization of all the subunits of replication factor C from a higher plant, rice (Oryza sativa L.), and their relation to development.

Journal: Plant molecular biology 20030901

Title: Analysis of cell cycle regulation by 1-mono-O-acyl-3-O-(alpha-D-sulfoquinovosyl)-glyceride (SQMG), an inhibitor of eukaryotic DNA polymerases.

Journal: Biochemical pharmacology 20030815

Title: Evidence that DNA replication is not regulated by ubiquitin-dependent proteolysis in Xenopus egg extract.

Journal: Experimental cell research 20030815

Title: Flow cytometric analysis of the cell cycle in different coconut palm (Cocos nucifera L.) tissues cultured in vitro.

Journal: Plant cell reports 20030801

Title: Different cell cycle regulation of vascular smooth muscle in genetic hypertension.

Journal: Hypertension (Dallas, Tex. : 1979) 20030801

Title: Activation of a p53-mediated apoptotic pathway in quiescent lymphocytes after the inhibition of DNA repair by fludarabine.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030801

Title: BY-2 cells: culture and transformation for live cell imaging.

Journal: Current protocols in cell biology 20030801

Title: ICBP90 belongs to a new family of proteins with an expression that is deregulated in cancer cells.

Journal: British journal of cancer 20030707

Title: Measuring the mitotic index in chemically-treated human lymphocyte cultures by flow cytometry.

Journal: Mutation research 20030606

Title: Spontaneous hair-cell renewal following gentamicin exposure in postnatal rat utricular explants.

Journal: Hearing research 20030601

Title: Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes.

Journal: The Journal of biological chemistry 20030530

Title: Tracking the cell cycle origins for escape from topotecan action by breast cancer cells.

Journal: British journal of cancer 20030422

Title: Diastereoselective formal total synthesis of the DNA polymerase alpha inhibitor, aphidicolin, using palladium-catalyzed cycloalkenylation and intramolecular Diels-Alder reactions.

Journal: Organic letters 20030417

Title: Increased error-prone NHEJ activity in myeloid leukemias is associated with DNA damage at sites that recruit key nonhomologous end-joining proteins.

Journal: Cancer research 20030415

Title: bHLH transcription factor Her5 links patterning to regional inhibition of neurogenesis at the midbrain-hindbrain boundary.

Journal: Development (Cambridge, England) 20030401

Title: Loss of p53 induces M-phase retardation following G2 DNA damage checkpoint abrogation.

Journal: Archives of biochemistry and biophysics 20030401

Title: Hypotonic buffer induces meiosis and formation of anucleate cytoplasmic islands in the egg of the two-spotted cricket Gryllus bimaculatus.

Journal: Development, growth & differentiation 20030401

Title: Oligomers of the arginine-rich motif of the HIV-1 TAT protein are capable of transferring plasmid DNA into cells.

Journal: The Journal of biological chemistry 20030328

Title: Cell cycle independent infection and gene transfer by recombinant Sendai viruses.

Journal: Journal of virological methods 20030301

Title: E2F-1 overexpression sensitizes colorectal cancer cells to camptothecin.

Journal: Cancer gene therapy 20030301

Title: Inducible p27(Kip1) expression inhibits proliferation of K562 cells and protects against apoptosis induction by proteasome inhibitors.

Journal: Cell death and differentiation 20030301

Title: Nuclear phosphoinositide 3-kinase C2beta activation during G2/M phase of the cell cycle in HL-60 cells.

Journal: Biochimica et biophysica acta 20030220

Title: Chk1-deficient tumour cells are viable but exhibit multiple checkpoint and survival defects.

Journal: The EMBO journal 20030203

Title: MuERV-L is one of the earliest transcribed genes in mouse one-cell embryos.

Journal: Biology of reproduction 20030201

Title: A genome-wide identification of E2F-regulated genes in Arabidopsis.

Journal: The Plant journal : for cell and molecular biology 20030201

Title: Inhibition of replication induces non-apoptotic cell death in fibroblast cell lines derived from LEC rats.

Journal: The Journal of veterinary medical science 20030201

Title: Latent HIV-1 reactivation in transgenic mice requires cell cycle -dependent demethylation of CREB/ATF sites in the LTR.

Journal: AIDS (London, England) 20030124

Title: Fragile sites and bladder cancer.

Journal: Cancer genetics and cytogenetics 20030115

Title: An in vitro model of pericardial tissue healing.

Journal: Biomaterials 20030101

Title: The use of the MTT assay to study drug resistance in fresh tumour samples.

Journal: Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20030101

Title: Induction of DNA damage responses by adozelesin is S phase-specific and dependent on active replication forks.

Journal: Molecular cancer therapeutics 20030101

Title: An ATR- and Cdc7-dependent DNA damage checkpoint that inhibits initiation of DNA replication.

Journal: Molecular cell 20030101

Title: Cell growth arrest by nucleotides, nucleosides and bases as a tool for improved production of recombinant proteins.

Journal: Biotechnology progress 20030101

Title: Expression of aphidicolin-induced fragile sites and their relationship between genetic susceptibility in breast cancer, ovarian cancer, and non-small-cell lung cancer patients.

Journal: Teratogenesis, carcinogenesis, and mutagenesis 20030101

Title: Differences in the way a mammalian cell and yeast cells coordinate cell growth and cell-cycle progression.

Journal: Journal of biology 20030101

Title: Entamoeba invadens: inhibition of excystation and metacystic development by aphidicolin.

Journal: Experimental parasitology 20030101

Title: Common fragile sites.

Journal: Cytogenetic and genome research 20030101

Title: Aphidicolin decreases ex vivo resistance to cytosine arabinoside in childhood acute leukaemia.

Journal: Oncology reports 20030101

Title: How common are common fragile sites in humans: interindividual variation in the distribution of aphidicolin-induced fragile sites.

Journal: Cytogenetic and genome research 20030101

Title: Behavior and differentiation process of pigment cells in a tropical sea urchin Echinometra mathaei.

Journal: Development, growth & differentiation 20030101

Title: Efficiency, specificity and DNA polymerase-dependence of translesion replication across the oxidative DNA lesion 8-oxoguanine in human cells.

Journal: Mutation research 20021229

Title: ATR regulates fragile site stability.

Journal: Cell 20021213

Title: An ACF1-ISWI chromatin-remodeling complex is required for DNA replication through heterochromatin.

Journal: Nature genetics 20021201

Title: Xath5 regulates neurogenesis in the Xenopus olfactory placode.

Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20021201

Title: Host DNA replication is induced by geminivirus infection of differentiated plant cells.

Journal: The Plant cell 20021201

Title: Delta MEKK3:ER* activation induces a p38 alpha/beta 2-dependent cell cycle arrest at the G2 checkpoint.

Journal: Oncogene 20021121

Title: HL60 cells halted in G1 or S phase differentiate normally.

Journal: Experimental cell research 20021115

Title: Cell cycle-regulated gene expression in Arabidopsis.

Journal: The Journal of biological chemistry 20021101

Title: Inducible DNA demethylation mediated by the maize Suppressor-mutator transposon-encoded TnpA protein.

Journal: The Plant cell 20021101

Title: Apoptosis of Spodoptera litura cells induced by AcMNPV ie-1 gene.

Journal: Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica 20021101

Title: Induction of multiple double-strand breaks within an hsr by meganucleaseI-SceI expression or fragile site activation leads to formation of double minutes and other chromosomal rearrangements.

Journal: Oncogene 20021031

Title: Stabilization of p53 and transactivation of its target genes in response to replication blockade.

Journal: Oncogene 20021017

Title: Induction of DNA ligase I by 1-beta-D-arabinosylcytosine and aphidicolin in MiaPaCa human pancreatic cancer cells.

Journal: Experimental cell research 20021015

Title: Regulation of epithelial cell migration and tumor formation by beta-catenin signaling.

Journal: Experimental cell research 20021015

Title: ATF is important to late S phase-dependent regulation of DNA topoisomerase IIalpha gene expression in HeLa cells.

Journal: Cancer letters 20021008

Title: Mutant alleles of Arabidopsis RADIALLY SWOLLEN 4 and 7 reduce growth anisotropy without altering the transverse orientation of cortical microtubules or cellulose microfibrils.

Journal: Development (Cambridge, England) 20021001

Title: Defective neurite outgrowth in aphidicolin/cAMP-induced motor neurons expressing mutant Cu/Zn superoxide dismutase.

Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20021001

Title: Cell cycle-dependent expression of an essential SMC-like protein and dynamic chromosome localization in the archaeon Halobacterium salinarum.

Journal: Molecular microbiology 20021001

Title: Dynamic organization of vacuolar and microtubule structures during cell cycle progression in synchronized tobacco BY-2 cells.

Journal: Plant & cell physiology 20020901

Title: Expression of folate sensitive and aphidicolin induced chromosomal fragile sites in familial neuroblastoma.

Journal: Journal of experimental & clinical cancer research : CR 20020901

Title: Wild-type p53 inhibits replication-associated homologous recombination.

Journal: Oncogene 20020829

Title: Base excision repair of adenine/8-oxoguanine mispairs by an aphidicolin-sensitive DNA polymerase in human cell extracts.

Journal: Oncogene 20020808

Title: Relationships among the cell cycle, cell proliferation, and aryl hydrocarbon receptor expression in PLHC-1 cells.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20020801

Title: Hydroxyurea significantly enhances tumor growth delay in vivo with herpes simplex virus thymidine kinase/ganciclovir gene therapy.

Journal: Gene therapy 20020801

Title: Dependence of DNA synthesis and in vitro development of bovine nuclear transfer embryos on the stage of the cell cycle of donor cells and recipient cytoplasts.

Journal: Biology of reproduction 20020801

Title: Studies on fertilization in the teleost IV. Effects of aphidicolin and camptothecin on chromosome formation in fertilized medaka eggs.

Journal: Development, growth & differentiation 20020801

Title: Mismatch repair in human nuclear extracts. Time courses and ATP requirements for kinetically distinguishable steps leading to tightly controlled 5' to 3' and aphidicolin-sensitive 3' to 5' mispair-provoked excision.

Journal: The Journal of biological chemistry 20020719

Title: Prolonged arrest of mammalian cells at the G1/S boundary results in permanent S phase stasis.

Journal: Journal of cell science 20020715

Title: The fragile histidine triad/common chromosome fragile site 3B locus and repair-deficient cancers.

Journal: Cancer research 20020715

Title: Over-expression of human DNA polymerase lambda in E. coli and characterization of the recombinant enzyme.

Journal: Genes to cells : devoted to molecular & cellular mechanisms 20020701

Title: Characterization of the bone-resorptive effect of interleukin-11 in cultured mouse calvarial bones.

Journal: Bone 20020701

Title: Identification of unstable sequences within the common fragile site at 3p14.2: implications for the mechanism of deletions within fragile histidine triad gene/common fragile site at 3p14.2 in tumors.

Journal: Cancer research 20020615

Title: Cell synchronization effect on mammalian cell permeabilization and gene delivery by electric field.

Journal: Biochimica et biophysica acta 20020613

Title: Matrix association of early- and late-replicating chromatin studied by single-cell electrophoresis.

Journal: Biochimica et biophysica acta 20020612

Title: Pyrido[2, 3-d]pyrimidines and pyrimido[5',4':5, 6]pyrido[2, 3-d]pyrimidines as new antiviral agents: synthesis and biological activity.

Journal: Archiv der Pharmazie 20020601

Title: DNA polymerase theta purified from human cells is a high-fidelity enzyme.

Journal: Journal of molecular biology 20020531

Title: Fragmentation and dispersal of the pericentriolar Golgi complex is required for entry into mitosis in mammalian cells.

Journal: Cell 20020503

Title: Inhibition of nucleotide excision repair by fludarabine in normal lymphocytes in vitro, measured by the alkaline single cell gel electrophoresis (Comet) assay.

Journal: Japanese journal of cancer research : Gann 20020501

Title: Cell cycle specific plasmid DNA replication in the nuclear extract of Saccharomyces cerevisiae: modulation by replication protein A and proliferating cell nuclear antigen.

Journal: Biochemistry 20020423

Title: Segment-specific expression of alkaline phosphatase in the Tubifex embryo requires DNA replication and mRNA synthesis.

Journal: The Journal of experimental zoology 20020415

Title: The role of the cell cycle on the efficiency of photochemical gene transfection.

Journal: Biochimica et biophysica acta 20020415

Title: Endoreduplication is not inhibited but induced by aphidicolin in cultured cells of tobacco.

Journal: Journal of experimental botany 20020401

Title: Induction of biphasic DNA double strand breaks and activation of multiple repair protein complexes by DNA topoisomerase I drug 7-ethyl-10-hydroxy-camptothecin.

Journal: Molecular pharmacology 20020401

Title: Process of pigment cell specification in the sand dollar, Scaphechinus mirabilis.

Journal: Development, growth & differentiation 20020401

Title: Synchronous Arabidopsis suspension cultures for analysis of cell-cycle gene activity.

Journal: The Plant journal : for cell and molecular biology 20020401

Title: The E2F family of transcription factors from Arabidopsis thaliana. Novel and conserved components of the retinoblastoma/E2F pathway in plants.

Journal: The Journal of biological chemistry 20020322

Title: Transcriptional regulation of mitotic genes by camptothecin-induced DNA damage: microarray analysis of dose- and time-dependent effects.

Journal: Cancer research 20020315

Title: Organophosphate-based pesticides and genetic damage implicated in bladder cancer.

Journal: Cancer genetics and cytogenetics 20020301

Title: Role of cell contact in the specification process of pigment founder cells in the sea urchin embryo.

Journal: Zoological science 20020301

Title: Aphidicolin induces 6-thioguanine resistant mutants in human diploid fibroblasts.

Journal: Mutation research 20020220

Title: Tumor necrosis factor-alpha exerts interleukin-6-dependent and -independent effects on cultured skeletal muscle cells.

Journal: Biochimica et biophysica acta 20020130

Title: Homologous recombination induced by replication inhibition, is stimulated by expression of mutant p53.

Journal: Oncogene 20020117

Title: Action of (E)-2'-deoxy-2'-(fluoromethylene)cytidine on DNA metabolism: incorporation, excision, and cellular response.

Journal: Molecular pharmacology 20020101

Title: Chromosomal fragile sites and relationship between genetic predisposition to small cell lung cancer.

Journal: Teratogenesis, carcinogenesis, and mutagenesis 20020101

Title: Repair of damaged DNA by Arabidopsis cell extract.

Journal: The Plant cell 20020101

Title: Fragile sites in human and Macaca fascicularis chromosomes are breakpoints in chromosome evolution.

Journal: Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 20020101

Title: Investigation of genetic susceptibility to non-small cell lung cancer by fragile site expression.

Journal: Teratogenesis, carcinogenesis, and mutagenesis 20020101

Title: Enhanced nucleotide excision repair in cisplatin resistant human KB carcinoma cells.

Journal: Oncology reports 20020101

Title: In vitro antiviral activity of aphidicolin and its derivates. Synergistic effects of aphidicolin with other antiviral drugs.

Journal: Arzneimittel-Forschung 20020101

Title: Enhanced sensitivity of G1 arrested human cancer cells suggests a novel therapeutic strategy using a combination of simvastatin and TRAIL.

Journal: Cell cycle (Georgetown, Tex.) 20020101

Title: Localisation of aphidicolin-induced break points in Holstein-Friesian cattle (Bos taurus) using RBG-banding.

Journal: Genetics, selection, evolution : GSE 20020101

Title: Genetic modification of human trabecular meshwork with lentiviral vectors.

Journal: Human gene therapy 20011120

Title: Characterization of the DNA polymerase gene of varicella-zoster viruses resistant to acyclovir.

Journal: The Journal of general virology 20011101

Title: A multistep model for paclitaxel-induced apoptosis in human breast cancer cell lines.

Journal: Experimental cell research 20011101

Title: Cladribine induces apoptosis in human leukaemia cells by caspase-dependent and -independent pathways acting on mitochondria.

Journal: The Biochemical journal 20011101

Title: Cell cycle-dependent control of polarised development by a cyclin-dependent kinase-like protein in the Fucus zygote.

Journal: Development (Cambridge, England) 20011101

Title: Total synthesis of (+/-)-stemodinone via an efficient ring-exchange strategy.

Journal: The Journal of organic chemistry 20011019

Title: Extracellular control of cell size.

Journal: Nature cell biology 20011001

Title: A new flow cytometric method to follow DNA gap filling during nucleotide excision repair of UVc-induced damage.

Journal: Cytometry 20011001

Title: Quiescence, cell viability, apoptosis and necrosis of smooth muscle cells using different growth inhibitors.

Journal: Cell proliferation 20011001

Title: 'Caged cytoskeletons': a rapid method for the isolation of microtubule-associated proteins from synchronized plant suspension cells.

Journal: The Plant journal : for cell and molecular biology 20011001

Title: Post-mitotic, differentiated myotubes efficiently produce retroviral vector from hybrid adeno-retrovirus templates.

Journal: Gene therapy 20011001

Title: p53 Protects renal inner medullary cells from hypertonic stress by restricting DNA replication.

Journal: American journal of physiology. Renal physiology 20010901

Title: Transfection of large plasmids in primary human myoblasts.

Journal: Gene therapy 20010901

Title: Arsenic trioxide induces G2/M growth arrest and apoptosis after caspase-3 activation and bcl-2 phosphorylation in promonocytic U937 cells.

Journal: Biochemical and biophysical research communications 20010831

Title: Reduced store-operated Ca(2+) currents in rat basophilic leukaemia cells cultured under serum-free conditions.

Journal: Cell calcium 20010801

Title: Ethylene induces cell death at particular phases of the cell cycle in the tobacco TBY-2 cell line.

Journal: Journal of experimental botany 20010801

Title: Characterization of homologous recombination induced by replication inhibition in mammalian cells.

Journal: The EMBO journal 20010716

Title: Expression, purification and characterization of the Spodoptera littoralis nucleopolyhedrovirus (SpliNPV) DNA polymerase and interaction with the SpliNPV non-hr origin of DNA replication.

Journal: The Journal of general virology 20010701

Title: Initial amplification of duck hepatitis B virus covalently closed circular DNA after in vitro infection of embryonic duck hepatocytes is increased by cell cycle progression.

Journal: Hepatology (Baltimore, Md.) 20010701

Title: Cell cycle regulation of cyclin-dependent kinases in tobacco cultivar Bright Yellow-2 cells.

Journal: Plant physiology 20010701

Title: Variation in adenovirus receptor expression and adenovirus vector-mediated transgene expression at defined stages of the cell cycle.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20010701

Title: Fate of nascent microtubules organized at the M/G1 interface, as visualized by synchronized tobacco BY-2 cells stably expressing GFP-tubulin: time-sequence observations of the reorganization of cortical microtubules in living plant cells.

Journal: Plant & cell physiology 20010701

Title: Maintenance of the DNA puff expanded state is independent of active replication and transcription.

Journal: Chromosoma 20010701

Title: Incomplete RNA polymerase II phosphorylation in Xenopus laevis early embryos.

Journal: Journal of cell science 20010701

Title: Inner cell mass-specific expression of a cell adhesion molecule (PECAM-1/CD31) in the mouse blastocyst.

Journal: Developmental biology 20010615

Title: Regulation of zygotic gene activation in the preimplantation mouse embryo: global activation and repression of gene expression.

Journal: Biology of reproduction 20010601

Title: Treatment of drug-resistant human neuroblastoma cells with cyclodextrin inclusion complexes of aphidicolin.

Journal: Anti-cancer drugs 20010601

Title: Differentiation between inducers of apoptosis and nonspecific cytotoxic drugs by means of cell analyzer and immunoassay.

Journal: Die Pharmazie 20010601

Title: Direct regulation of the centrosome duplication cycle by the p53-p21Waf1/Cip1 pathway.

Journal: Oncogene 20010531

Title: Cloning and functional expression of cDNA encoding aphidicolan-16 beta-ol synthase: a key enzyme responsible for formation of an unusual diterpene skeleton in biosynthesis of aphidicolin.

Journal: Journal of the American Chemical Society 20010530

Title: Aphidicolin triggers a block to replication origin firing in Xenopus egg extracts.

Journal: The Journal of biological chemistry 20010518

Title: Delaying S-phase progression rescues cells from heat-induced S-phase hypertoxicity.

Journal: Journal of cellular physiology 20010501

Title: Analysis of repair and PCNA complex formation induced by ionizing radiation in human fibroblast cell lines.

Journal: Mutagenesis 20010501

Title: Werner helicase relocates into nuclear foci in response to DNA damaging agents and co-localizes with RPA and Rad51.

Journal: Genes to cells : devoted to molecular & cellular mechanisms 20010501

Title: Methods for synchronizing cells at specific stages of the cell cycle.

Journal: Current protocols in cell biology 20010501

Title: The cellular response to DNA damage induced by the enediynes C-1027 and neocarzinostatin includes hyperphosphorylation and increased nuclear retention of replication protein a (RPA) and trans inhibition of DNA replication.

Journal: Biochemistry 20010417

Title: Cell cycle-related changes in regulatory volume decrease and volume-sensitive chloride conductance in mouse fibroblasts.

Journal: Journal of cellular physiology 20010401

Title: Loss of cyclin A and G1-cell cycle arrest are a prerequisite of ceramide-induced toxicity in human arterial endothelial cells.

Journal: Cardiovascular research 20010401

Title: p53 is dispensable for UV-induced cell cycle arrest at late G(1) in mammalian cells.

Journal: Carcinogenesis 20010401

Title: DNA replication and daughter cell budding are not tightly linked in the protozoan parasite Toxoplasma gondii.

Journal: Microbes and infection 20010401

Title: Induction of the common fragile site FRA3B does not affect FHIT expression.

Journal: Oncogene 20010329

Title: Human DNA polymerase beta initiates DNA synthesis during long-patch repair of reduced AP sites in DNA.

Journal: The EMBO journal 20010315

Title: Circumvention of ara-C resistance by aphidicolin in blast cells from patients with AML.

Journal: British journal of cancer 20010301

Title: Swelling-activated taurine and K+ transport in human cervical cancer cells: association with cell cycle progression.

Journal: Pflugers Archiv : European journal of physiology 20010301

Title: The efficiency of simian foamy virus vector type-1 (SFV-1) in nondividing cells and in human PBLs.

Journal: Virology 20010215

Title: Differences in DNA synthesis in vitro using isolated nuclei from regenerating livers of young and aged rats.

Journal: Mechanisms of ageing and development 20010201

Title: Inhibition of N-myc expression and induction of apoptosis by iron chelation in human neuroblastoma cells.

Journal: Cancer research 20010201

Title: Identification of DNA polymerase delta in eggs of a teleost fish (loach).

Journal: Biochemistry. Biokhimiia 20010201

Title: Early stages of p53-induced apoptosis are reversible.

Journal: Cell death and differentiation 20010201

Title: De novo activation of the beta-phaseolin promoter by phosphatase or protein synthesis inhibitors.

Journal: The Journal of biological chemistry 20010119

Title: Activation of deoxycytidine kinase by inhibition of DNA synthesis in human lymphocytes.

Journal: Biochemical pharmacology 20010115

Title: The nuclear death domain protein p84N5 activates a G2/M cell cycle checkpoint prior to the onset of apoptosis.

Journal: The Journal of biological chemistry 20010112

Title: Purification and characterization of pol kappa, a DNA polymerase encoded by the human DINB1 gene.

Journal: The Journal of biological chemistry 20010105

Title: Cell division activity during apical hook development.

Journal: Plant physiology 20010101

Title: Critical assessment of the nuclear import of plasmid during cationic lipid-mediated gene transfer.

Journal: The journal of gene medicine 20010101

Title: Expression of VACM-1 protein in cultured rat adrenal endothelial cells is linked to the cell cycle.

Journal: Endothelium : journal of endothelial cell research 20010101

Title: Towards a virtual Arabidopsis plant.

Journal: Genome biology 20010101

Title: Uracil-initiated base excision DNA repair synthesis fidelity in human colon adenocarcinoma LoVo and Escherichia coli cell extracts.

Journal: Progress in nucleic acid research and molecular biology 20010101

Title: Expression of AAV Rep proteins in SV40-transformed and untransformed cells: reciprocal interaction with host DNA synthesis.

Journal: Intervirology 20010101

Title: Transcription and temporal cascade in Chilo iridescent virus infected cells.

Journal: Archives of virology 20010101

Title: Naphthalene carboxamides as inhibitors of human cytomegalovirus DNA polymerase.

Journal: Bioorganic & medicinal chemistry letters 20000918

Title: Synthesis and biological evaluation of certain alpha,beta-unsaturated ketones and their corresponding fused pyridines as antiviral and cytotoxic agents.

Journal: Journal of medicinal chemistry 20000727

Title: Herpes simplex type1:lacZ recombinant viruses. II. Microtiter plate-based colorimetric assays for the discovery of new antiherpes agents and the points at which such agents disrupt the viral replication cycle.

Journal: Antiviral research 19951101

Title: Bufalin induces apoptosis and influences the expression of apoptosis-related genes in human leukemia cells.

Journal: Leukemia research 19950801

Title: Alteration of the phosphorylation state of p34cdc2 kinase by the flavone L86-8275 in breast carcinoma cells. Correlation with decreased H1 kinase activity.

Journal: Biochemical pharmacology 19931117

Title: Isosteres of the DNA polymerase inhibitor aphidicolin as potential antiviral agents against human herpes viruses.

Journal: Journal of medicinal chemistry 19931112

Title: Transformation of BALB/c-3T3 cells: IV. Rank-ordered potency of 24 chemical responses detected in a sensitive new assay procedure.

Journal: Environmental health perspectives 19930701

Title: G2 delay induced by nitrogen mustard in human cells affects cyclin A/cdk2 and cyclin B1/cdc2-kinase complexes differently.

Journal: The Journal of biological chemistry 19930415

Title: Pentoxifylline and other methyl xanthines inhibit interleukin-2 receptor expression in human lymphocytes.

Journal: Cellular immunology 19910701

Title: Herpes simplex virus-specified DNA polymerase is the target for the antiviral action of 9-(2-phosphonylmethoxyethyl)adenine.

Journal: The Journal of biological chemistry 19910105

Title: Antiviral agents of plant origin. II. Antiviral activity of scopadulcic acid B derivatives.

Journal: Chemical & pharmaceutical bulletin 19900101

Title: Mechanism of inhibition of herpes simplex virus and vaccinia virus DNA polymerases by aphidicolin, a highly specific inhibitor of DNA replication in eucaryotes.

Journal: Journal of virology 19801101

Title: Effect of aphidicolin on viral and human DNA polymerases.

Journal: Biochemical and biophysical research communications 19790627

Title: Antiviral effects of aphidicolin, a new antibiotic produced by Cephalosporium aphidicola.

Journal: Antimicrobial agents and chemotherapy 19730901

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Tags:38966-21-1 Molecular Formula|38966-21-1 MDL|38966-21-1 SMILES|38966-21-1 8,11|á-Methano-11aH-cyclohepta[a]naphthalene-4,9-dimethanol,tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-, (3R,4R,4aR,6aS,8R,9R,11aS,11bS)-