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40045-50-9,MFCD01927019
Catalog No.:AA0075XU

40045-50-9 | SU 3327

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Purity
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5mg
≥98%
in stock  
$139.00   $97.00
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10mg
≥98%
in stock  
$222.00   $155.00
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250mg
98% HPLC
in stock  
$222.00   $156.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0075XU
Chemical Name:
SU 3327
CAS Number:
40045-50-9
Molecular Formula:
C5H3N5O2S3
Molecular Weight:
261.3046
MDL Number:
MFCD01927019
SMILES:
[O-][N+](=O)c1cnc(s1)Sc1nnc(s1)N
Properties
Computed Properties
 
Complexity:
251  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
1.9  

Downstream Synthesis Route

[1]EuropeanJournalofMedicinalChemistry,1981,vol.16,p.233-239

[2]JournalofMedicinalChemistry,2009,vol.52,p.1943-1952

37366-09-9    40045-50-9    1203507-02-1   
C30H26Cl2N7O2RuS4(1+)*Cl(1-) 

[1]Patent:CN108794543,2018,A.Locationinpatent:Paragraph0035

Literature

Title: Design, synthesis, and structure-activity relationship of substrate competitive, selective, and in vivo active triazole and thiadiazole inhibitors of the c-Jun N-terminal kinase.

Journal: Journal of medicinal chemistry 20090409

Title: De SK, et al. Design, synthesis, and structure-activity relationship of substrate competitive, selective, and in vivo active triazole and thiadiazole inhibitors of the c-Jun N-terminal kinase. J Med Chem. 2009 Apr 9;52(7):1943-52.

Title: Augustine C, et al. Traumatic injury elicits JNK-mediated human astrocyte retraction in vitro. Neuroscience. 2014 Aug 22;274:1-10.

Title: Serizawa F, et al. Pretreatment of human cerebrovascular endothelial cells with CO-releasing molecule-3 interferes with JNK/AP-1 signaling and suppresses LPS-induced proadhesive phenotype. Microcirculation. 2015 Jan;22(1):28-36.

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SDS
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