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40246-10-4,MFCD00800711
Catalog No.:AA00I7TI

40246-10-4 | Glycitin

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Purity
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1mg
98%
in stock  
$11.00   $8.00
- +
5mg
98%
in stock  
$22.00   $15.00
- +
10mg
98%
in stock  
$29.00   $21.00
- +
25mg
98%
in stock  
$50.00   $35.00
- +
50mg
98%
in stock  
$77.00   $54.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00I7TI
Chemical Name:
Glycitin
CAS Number:
40246-10-4
Molecular Formula:
C22H22O10
Molecular Weight:
446.4041
MDL Number:
MFCD00800711
SMILES:
OCC1OC(Oc2cc3occ(c(=O)c3cc2OC)c2ccc(cc2)O)C(C(C1O)O)O
Properties
Computed Properties
 
Complexity:
690  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
5  
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
5  
XLogP3:
0.6  

Upstream Synthesis Route

[1]JournalofPharmacologyandExperimentalTherapeutics,2007,vol.320,#3,p.1237-1245

[2]JournalofAgriculturalandFoodChemistry,2012,vol.60,#6,p.1535-1541

[1]EuropeanJournalofOrganicChemistry,2008,#33,p.5622-5629

[1]Molecules,2010,vol.15,#8,p.5153-5161

[1]LiebigsAnnales,1996,#10,p.1651-1652

[1]LiebigsAnnales,1996,#10,p.1651-1652

Downstream Synthesis Route
Solgen40 
  40246-10-4    552-66-9    529-59-9 

[1]Patent:WO2004/43945,2004,A1.Locationinpatent:Page9-10

[2]Patent:WO2004/43945,2004,A1.Locationinpatent:Page9-10

[3]Patent:WO2004/43945,2004,A1.Locationinpatent:Page9-10

[4]Patent:WO2004/43945,2004,A1.Locationinpatent:Page9-10

[5]Patent:WO2004/43945,2004,A1.Locationinpatent:Page9-10

[6]Patent:WO2004/43945,2004,A1.Locationinpatent:Page9-10

[7]Patent:WO2004/43945,2004,A1.Locationinpatent:Page9-10

[8]Patent:WO2004/43945,2004,A1.Locationinpatent:Page9-10

[9]Patent:WO2004/43945,2004,A1.Locationinpatent:Page9-10

ADMNovasoy 
  40246-10-4    552-66-9    529-59-9 

[1]Patent:WO2004/43945,2004,A1.Locationinpatent:Page8

Literature

Title: Continuous soy isoflavones exposure from weaning to maturity induces downregulation of ovarian steroidogenic factor 1 gene expression and corresponding changes in DNA methylation pattern.

Journal: Toxicology letters 20171105

Title: A risk assessment-driven quantitative comparison of gene expression profiles in PBMCs and white adipose tissue of humans and rats after isoflavone supplementation.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20160901

Title: Hydrolysis of isoflavone glycosides by a thermostable β-glucosidase from Pyrococcus furiosus.

Journal: Journal of agricultural and food chemistry 20120215

Title: Equol is more active than soy isoflavone itself to compete for binding to thromboxane A(2) receptor in human platelets.

Journal: Thrombosis research 20090301

Title: [Isoflavone glycosides from the bark of Maackia amurensis].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20090101

Title: Ultrahigh-pressure liquid chromatography of isoflavones and phenolic acids on different stationary phases.

Journal: Journal of chromatography. A 20080627

Title: Enhanced bioavailability of soy isoflavones by complexation with beta-cyclodextrin in rats.

Journal: Bioscience, biotechnology, and biochemistry 20071201

Title: Inhibitory effects of glycitein on hydrogen peroxide induced cell damage by scavenging reactive oxygen species and inhibiting c-Jun N-terminal kinase.

Journal: Free radical research 20070601

Title: Flavonoids possess neuroprotective effects on cultured pheochromocytoma PC12 cells: a comparison of different flavonoids in activating estrogenic effect and in preventing beta-amyloid-induced cell death.

Journal: Journal of agricultural and food chemistry 20070321

Title: Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.

Journal: Journal of molecular graphics & modelling 20061101

Title: [Preparation of soybean isoflavone glucosides by reversed-phase high performance liquid chromatography].

Journal: Se pu = Chinese journal of chromatography 20060701

Title: Effect of daidzin, genistin, and glycitin on osteogenic and adipogenic differentiation of bone marrow stromal cells and adipocytic transdifferentiation of osteoblasts.

Journal: Acta pharmacologica Sinica 20050901

Title: Simultaneous determination of isoflavones and bisphenol A in rat serum by high-performance liquid chromatography coupled with coulometric array detection.

Journal: Bioscience, biotechnology, and biochemistry 20040101

Title: Isoflavone, glyphosate, and aminomethylphosphonic acid levels in seeds of glyphosate-treated, glyphosate-resistant soybean.

Journal: Journal of agricultural and food chemistry 20030101

Title: Determination of isoflavones in ready-to-feed soy-based infant formula.

Journal: Journal of AOAC International 20030101

Title: Stabilities of daidzin, glycitin, genistin, and generation of derivatives during heating.

Journal: Journal of agricultural and food chemistry 20021204

Title: Efficacy and safety of a phytoestrogen preparation derived from Glycine max (L.) Merr in climacteric symptomatology: a multicentric, open, prospective and non-randomized trial.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20020301

Title: Comparative study on reduction of bone loss and lipid metabolism abnormality in ovariectomized rats by soy isoflavones, daidzin, genistin, and glycitin.

Journal: Biological & pharmaceutical bulletin 20010401

Title: Determination of isoflavones in soy and selected foods containing soy by extraction, saponification, and liquid chromatography: collaborative study.

Journal: Journal of AOAC International 20010101

Title: Uesugi T, et al. Comparative study on reduction of bone loss and lipid metabolism abnormality in ovariectomized rats by soy isoflavones, daidzin, genistin, and glycitin. Biol Pharm Bull. 2001 Apr;24(4):368-72.

Title: Li XH, et al. Effect of daidzin, genistin, and glycitin on osteogenic and adipogenic differentiation of bone marrow stromal cells and adipocytic transdifferentiation of osteoblasts. Acta Pharmacol Sin. 2005 Sep;26(9):1081-6.

Title: Zhang L, et al. Glycitin regulates osteoblasts through TGF-β or AKT signaling pathways in bone marrow stem cells. Exp Ther Med. 2016 Nov;12(5):3063-3067.

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