Home Other Building Blocks 41354-29-4
41354-29-4,MFCD00150043
Catalog No.:AA00I80F

41354-29-4 | Cyproheptadine hydrochloride sesquihydrate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5g
>98.0%(T)(HPLC)
in stock  
$24.00   $17.00
- +
25g
>98.0%(T)(HPLC)
in stock  
$70.00   $49.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00I80F
Chemical Name:
Cyproheptadine hydrochloride sesquihydrate
CAS Number:
41354-29-4
Molecular Formula:
C42H50Cl2N2O3
Molecular Weight:
701.7640
MDL Number:
MFCD00150043
SMILES:
CN1CCC(=C2c3ccccc3C=Cc3c2cccc3)CC1.CN1CCC(=C2c3ccccc3C=Cc3c2cccc3)CC1.Cl.Cl.O.O.O
Properties
Computed Properties
 
Complexity:
423  
Covalently-Bonded Unit Count:
7  
Heavy Atom Count:
49  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
5  

Literature

Title: Bioavailable inhibitors of HIV-1 RNA biogenesis identified through a Rev-based screen.

Journal: Biochemical pharmacology 20160501

Title: Mechanisms of high-dose citalopram-induced death in a rat model.

Journal: Toxicology 20121216

Title: Potentiation of acid-sensing ion channel activity by the activation of 5-HT₂ receptors in rat dorsal root ganglion neurons.

Journal: Neuropharmacology 20120901

Title: Neurotransmitter-mediated action of an antagonist of growth hormone-releasing hormone on anxiolysis in mice.

Journal: Behavioural brain research 20120715

Title: Rupatadine 10 mg in the treatment of immediate mosquito-bite allergy.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20120701

Title: Life beyond kinases: structure-based discovery of sorafenib as nanomolar antagonist of 5-HT receptors.

Journal: Journal of medicinal chemistry 20120628

Title: A clozapine-like effect of cyproheptadine on progressive ratio schedule performance.

Journal: Journal of psychopharmacology (Oxford, England) 20120601

Title: Mechanisms of action of selective serotonin reuptake inhibitors in Daphnia magna.

Journal: Environmental science & technology 20120306

Title: Chemometrics optimization of six antihistamines separations by capillary electrophoresis with electrochemiluminescence detection.

Journal: Talanta 20120115

Title: Quantification of cyproheptadine in human plasma by high-performance liquid chromatography coupled to electrospray tandem mass spectrometry in a bioequivalence study.

Journal: Biomedical chromatography : BMC 20120101

Title: Recognition and management of perioperative serotonin syndrome.

Journal: American journal of otolaryngology 20120101

Title: Serotonin toxicity in aripiprazole augmentation.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20120101

Title: A comparative study of loratadine syrup and cyproheptadine HCL solution for treating perennial allergic rhinitis in Taiwanese children aged 2-12 years.

Journal: International journal of immunopathology and pharmacology 20120101

Title: Evaluation of the degree of mixing of combinations of dry syrup, powder, and fine granule products in consideration of particle size distribution using near infrared spectrometry.

Journal: Chemical & pharmaceutical bulletin 20120101

Title: Cyproheptadine enhances the I(K) of mouse cortical neurons through sigma-1 receptor-mediated intracellular signal pathway.

Journal: PloS one 20120101

Title: Unexpected remission of hepatocellular carcinoma (HCC) with lung metastasis to the combination therapy of thalidomide and cyproheptadine: report of two cases and a preliminary HCC cell line study.

Journal: BMJ case reports 20120101

Title: The effect of nutrition on the neural mechanisms potentially involved in melatonin-stimulated LH secretion in female Mediterranean goats.

Journal: The Journal of endocrinology 20111201

Title: Rupatadine and levocetirizine in chronic idiopathic urticaria: a comparative study of efficacy and safety.

Journal: Journal of drugs in dermatology : JDD 20111201

Title: Pharmacological treatment of abdominal pain related functional gastrointestinal disorders.

Journal: Journal of pediatric gastroenterology and nutrition 20111201

Title: Fixed drug eruption against rupatadine fumarate.

Journal: The Journal of craniofacial surgery 20110901

Title: Determination of azatadine in human plasma by liquid chromatography/tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110801

Title: Review of the epidemiology and characteristics of intentional cyproheptadine overdose in Hong Kong.

Journal: Clinical toxicology (Philadelphia, Pa.) 20110801

Title: The acute effects of mirtazapine on pain related behavior in healthy animals.

Journal: Neurosciences (Riyadh, Saudi Arabia) 20110701

Title: Effect of a serotonin antagonist on delay in grip muscle relaxation for persons with chronic hemiparetic stroke.

Journal: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20110401

Title: Involvement of monoaminergic systems in the antidepressant-like effect of nobiletin.

Journal: Physiology & behavior 20110110

Title: A case of cutaneous mastocytosis in a child with prominent Langerhans cell infiltration.

Journal: Pediatric dermatology 20110101

Title: Rupatadine for the treatment of allergic rhinitis and urticaria.

Journal: Expert review of clinical immunology 20110101

Title: Cyclic vomiting syndrome in Taiwanese children.

Journal: Journal of the Formosan Medical Association = Taiwan yi zhi 20110101

Title: Rupatadine improves nasal symptoms, quality of life (ESPRINT-15) and severity in a subanalysis of a cohort of Spanish allergic rhinitis patients.

Journal: Journal of investigational allergology & clinical immunology 20110101

Title: Efficacy and tolerability of rupatadine at four times the recommended dose against histamine- and platelet-activating factor-induced flare responses and ex vivo platelet aggregation in healthy males.

Journal: The British journal of dermatology 20101201

Title: Hydrogen sulphide induces mouse paw oedema through activation of phospholipase A2.

Journal: British journal of pharmacology 20101201

Title: Diabetogenic effect of a series of tricyclic delta opioid agonists structurally related to cyproheptadine.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20101001

Title: 74-year-old woman with new-onset myoclonus.

Journal: Mayo Clinic proceedings 20101001

Title: Sertraline-induced serotonin syndrome followed by mirtazapine reaction.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20100816

Title: Proconvulsant potential of cyproheptadine in experimental animal models.

Journal: Fundamental & clinical pharmacology 20100801

Title: Rupatadine and levocetirizine for seasonal allergic rhinitis: a comparative study of efficacy and safety.

Journal: Archives of otolaryngology--head & neck surgery 20100801

Title: Screening of OATP1B1/3 and OCT1 inhibitors in cryopreserved hepatocytes in suspension.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100711

Title: Rupatadine does not potentiate the CNS depressant effects of lorazepam: randomized, double-blind, crossover, repeated dose, placebo-controlled study.

Journal: British journal of clinical pharmacology 20100601

Title: Biogenic amines modulate pulse rate in the dorsal blood vessel of Lumbriculus variegatus.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20100501

Title: No cardiac effects of therapeutic and supratherapeutic doses of rupatadine: results from a 'thorough QT/QTc study' performed according to ICH guidelines.

Journal: British journal of clinical pharmacology 20100401

Title: [Erythropoiesis-stimulating properties of an antiserotonin drug under cytostatic treatment conditions].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20100301

Title: [Rupatadine, oral Rupatall].

Journal: Journal de pharmacie de Belgique 20100301

Title: Serotonin syndrome after administration of milnacipran for fibromyalgia.

Journal: Neurology 20100223

Title: Rupatadine inhibits proinflammatory mediator secretion from human mast cells triggered by different stimuli.

Journal: International archives of allergy and immunology 20100101

Title: Rupatadine and heart rhythm disturbances.

Journal: Clinical pharmacology and therapeutics 20100101

Title: Comparative evaluation of antipruritic protocols in acute burns. The emerging value of gabapentin in the treatment of burns pruritus.

Journal: Journal of burn care & research : official publication of the American Burn Association 20100101

Title: Rupatadine and its effects on symptom control, stimulation time, and temperature thresholds in patients with acquired cold urticaria.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20100101

Title: Rupatadine improves nasal symptoms, airflow and inflammation in patients with persistent allergic rhinitis: a pilot study.

Journal: Journal of biological regulators and homeostatic agents 20100101

Title: Localized cold urticaria to the face in a pediatric patient: a case report and literature review.

Journal: Pediatric dermatology 20100101

Title: Development and validation of LC-MS/MS method for the determination of cyproheptadine in several pharmaceutical syrup formulations.

Journal: Journal of pharmaceutical and biomedical analysis 20091205

Title: Prophylactic drugs and cytokine and leptin levels in children with migraine.

Journal: Pediatric neurology 20091001

Title: [Observation on therapeutic effect of He's Santong needling methods on cold erythema multiforme].

Journal: Zhongguo zhen jiu = Chinese acupuncture & moxibustion 20091001

Title: A fatality due to cyproheptadine and citalopram.

Journal: Journal of analytical toxicology 20091001

Title: Treatment of acquired cold urticaria with rupatadine.

Journal: Allergy 20090901

Title: The use of a responder analysis to identify clinically meaningful differences in chronic urticaria patients following placebo- controlled treatment with rupatadine 10 and 20 mg.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20090901

Title: The anti-histaminic cyproheptadine synergizes the antineoplastic activity of bortezomib in mantle cell lymphoma through its effects as a histone deacetylase inhibitor.

Journal: British journal of haematology 20090901

Title: Assessment of 5-hydroxytryptamine efflux in rat brain during a mild, moderate and severe serotonin-toxicity syndrome.

Journal: European journal of pharmacology 20090801

Title: Potentiation of the stimulatory effect of erythropoietin on erythropoiesis by antiserotonin drug during cytostatic myelosuppression.

Journal: Bulletin of experimental biology and medicine 20090701

Title: Anticonvulsant effect of Ficus religiosa: role of serotonergic pathways.

Journal: Journal of ethnopharmacology 20090622

Title: Pharmacological profile, efficacy and safety of rupatadine in allergic rhinitis.

Journal: Primary care respiratory journal : journal of the General Practice Airways Group 20090601

Title: Unsuspected polymorphic metabolism of rupatadine via its primary metabolite, desloratadine.

Journal: Primary care respiratory journal : journal of the General Practice Airways Group 20090601

Title: Cyproheptadine prevents pergolide-induced valvulopathy in rats: an echocardiographic and histopathological study.

Journal: American journal of physiology. Heart and circulatory physiology 20090601

Title: Successful treatment in a child with feeding problems and growth failure.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20090601

Title: Heart rhythm disturbances associated with rupatadine: a case series from the Spanish and Portuguese pharmacovigilance systems.

Journal: Clinical pharmacology and therapeutics 20090501

Title: Application of dummy molecularly imprinted solid-phase extraction in the analysis of cyproheptadine in bovine urine.

Journal: Journal of separation science 20090501

Title: Childhood virilization and adrenal suppression after ingestion of methandienone and cyproheptadine.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20090501

Title: Germinating seeds of the mung bean, Vigna radiata (Fabaceae), as a model for the preliminary evaluation of cytotoxic effects of drugs.

Journal: Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al 20090401

Title: Development and validation of an LC-MS/MS confirmatory method for residue analysis of cyproheptadine in urine of food-producing animals.

Journal: Journal of agricultural and food chemistry 20090325

Title: Torsade de pointes associated with rupatadine.

Journal: Revista espanola de cardiologia 20090301

Title: Simultaneous determination of rupatadine and its metabolite desloratadine in human plasma by a sensitive LC-MS/MS method: application to the pharmacokinetic study in healthy Chinese volunteers.

Journal: Journal of pharmaceutical and biomedical analysis 20090220

Title: Successful treatment of chronic drug-resistant urticaria with alprazolam.

Journal: The Journal of allergy and clinical immunology 20090201

Title: Syntheses of molecularly imprinted polymers: Molecular recognition of cyproheptadine using original print molecules and azatadine as dummy templates.

Journal: Analytica chimica acta 20090112

Title: Future directions in evaluating cancer-associated cachexia.

Journal: Journal of pediatric hematology/oncology 20090101

Title: Safety of rupatadine administered over a period of 1 year in the treatment of persistent allergic rhinitis: a multicentre, open-label study in Spain.

Journal: Drug safety 20090101

Title: Futura study: evaluation of efficacy and safety of rupatadine fumarate in the treatment of persistent allergic rhinitis.

Journal: Brazilian journal of otorhinolaryngology 20090101

Title: Reduction of nasal volume after allergen-induced rhinitis in patients treated with rupatadine: a randomized, cross-over, double-blind, placebo-controlled study.

Journal: Journal of investigational allergology & clinical immunology 20090101

Title: Cyproheptadine for the treatment of functional abdominal pain in childhood: a double-blinded randomized placebo-controlled trial.

Journal: Minerva pediatrica 20081201

Title: [Cyproheptadine-induced urinary obstruction].

Journal: Anales de pediatria (Barcelona, Spain : 2003) 20081201

Title: The effect of cyproheptadine hydrochloride (periactin) and megestrol acetate (megace) on weight in children with cancer/treatment-related cachexia.

Journal: Journal of pediatric hematology/oncology 20081101

Title: [In vitro potentiation of chloroquine activity in Plasmodium falciparum by ketotifen and cyproheptadine].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20081030

Title: Determination of rupatadine in pharmaceutical formulations by a validated stability-indicating MEKC method.

Journal: Journal of separation science 20080901

Title: North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition consensus statement on the diagnosis and management of cyclic vomiting syndrome.

Journal: Journal of pediatric gastroenterology and nutrition 20080901

Title: Serotonin syndrome triggered by a single dose of suboxone.

Journal: The American journal of emergency medicine 20080901

Title: Pharmacokinetic and safety profile of rupatadine when coadministered with azithromycin at steady-state levels: a randomized, open-label, two-way, crossover, Phase I study.

Journal: Clinical therapeutics 20080901

Title: High performance liquid chromatography-tandem mass spectrometric determination of rupatadine in human plasma and its pharmacokinetics.

Journal: Journal of pharmaceutical and biomedical analysis 20080805

Title: Cyproheptadine displays preclinical activity in myeloma and leukemia.

Journal: Blood 20080801

Title: Characterization of serotonin-toxicity syndrome (toxidrome) elicited by 5-hydroxy-l-tryptophan in clorgyline-pretreated rats.

Journal: European journal of pharmacology 20080707

Title: A 12-week placebo-controlled study of rupatadine 10 mg once daily compared with cetirizine 10 mg once daily, in the treatment of persistent allergic rhinitis.

Journal: Allergy 20080701

Title: Spatial-specific action of serotonin within the leech midbody ganglion.

Journal: Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20080601

Title: Shapiro syndrome with hypothalamic hypothyroidism.

Journal: Arquivos de neuro-psiquiatria 20080601

Title: [Torsades de pointes associated with rupatadine].

Journal: Revista espanola de cardiologia 20080301

Title: Life-threatening serotonin toxicity due to a citalopram-fluconazole drug interaction: case reports and discussion.

Journal: General hospital psychiatry 20080101

Title: Antihistaminic effects of rupatadine and PKPD modelling.

Journal: European journal of drug metabolism and pharmacokinetics 20080101

Title: Appetite stimulants in cystic fibrosis: a systematic review.

Journal: Journal of human nutrition and dietetics : the official journal of the British Dietetic Association 20071201

Title: Cyproheptadine for pediatric intrathecal baclofen withdrawal: a case report.

Journal: American journal of physical medicine & rehabilitation 20071201

Title: [Nelson's syndrome management: current knowledge].

Journal: La Revue de medecine interne 20071101

Title: The metabolism of serotonin in neuronal cells in culture and platelets.

Journal: Experimental brain research 20071101

Title: Effects of cyproheptadine and cetirizine on eosinophilic airway inflammation in cats with experimentally induced asthma.

Journal: American journal of veterinary research 20071101

Title: First time, low dose citalopram use-related serotonin syndrome.

Journal: Neurotoxicology 20071101

Title: Calotropis procera latex-induced inflammatory hyperalgesia - effect of bradyzide and morphine.

Journal: Autonomic & autacoid pharmacology 20070701

Title: Lack of effects between rupatadine 10 mg and placebo on actual driving performance of healthy volunteers.

Journal: Human psychopharmacology 20070701

Title: Identification of a key amino acid of the human 5-HT(2B) serotonin receptor important for sarpogrelate binding.

Journal: Journal of pharmacological sciences 20070701

Title: Pharmacological characterization of a chronic pruritus model induced by multiple application of 2,4,6-trinitrochlorobenzene in NC mice.

Journal: European journal of pharmacology 20070601

Title: Prolonged anticholinergic delirium following antihistamine overdose.

Journal: Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists 20070601

Title: Rupatadine in the treatment of chronic idiopathic urticaria: a double-blind, randomized, placebo-controlled multicentre study.

Journal: Allergy 20070501

Title: Influence of food on the oral bioavailability of rupatadine tablets in healthy volunteers: a single-dose, randomized, open-label, two-way crossover study.

Journal: Clinical therapeutics 20070501

Title: Cyproheptadine resembles clozapine in vivo following both acute and chronic administration in rats.

Journal: Journal of psychopharmacology (Oxford, England) 20070301

Title: Influences of histamine H1 receptor antagonists on maximal electroshock seizure in infant rats.

Journal: Biological & pharmaceutical bulletin 20070301

Title: [Protective effect of rupatadine against oleic acid-induced acute lung injury in rabbits].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20070301

Title: Effects of some H1-antagonists on the sleep-wake cycle in sleep-disturbed rats.

Journal: Journal of pharmacological sciences 20070201

Title: Interactive effect of histamine and prostaglandin D2 on nasal allergic symptoms in rats.

Journal: European journal of pharmacology 20070112

Title: The effect of a first-generation antihistamine on sputum viscoelasticity in cystic fibrosis.

Journal: Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 20070101

Title: Once-daily rupatadine improves the symptoms of chronic idiopathic urticaria: a randomised, double-blind, placebo-controlled study.

Journal: European journal of dermatology : EJD 20070101

Title: Acquired Blaschkoid dermatitis.

Journal: Indian journal of dermatology, venereology and leprology 20070101

Title: The proarrhythmic antihistaminic drug terfenadine increases spontaneous calcium release in human atrial myocytes.

Journal: European journal of pharmacology 20061228

Title: Locomotor and peripheral effects of sibutramine modulated by 5-HT2 receptors.

Journal: Canadian journal of physiology and pharmacology 20061201

Title: New antihistamines: a critical view.

Journal: Jornal de pediatria 20061101

Title: Discovery, structure-activity relationship study, and oral analgesic efficacy of cyproheptadine derivatives possessing N-type calcium channel inhibitory activity.

Journal: Bioorganic & medicinal chemistry 20060801

Title: ADHD and insomnia.

Journal: Journal of the American Academy of Child and Adolescent Psychiatry 20060401

Title: Role of substance P in allergic nasal symptoms in rats.

Journal: European journal of pharmacology 20060217

Title: Refractory coronary vasospasm following drug-eluting stent placement treated with cyproheptadine.

Journal: The Journal of invasive cardiology 20060201

Title: Evaluation of the cognitive, psychomotor and pharmacokinetic profiles of rupatadine, hydroxyzine and cetirizine, in combination with alcohol, in healthy volunteers.

Journal: Human psychopharmacology 20060101

Title: Evidence supporting a role of serotonin in modulation of sudden death induced by seizures in DBA/2 mice.

Journal: Epilepsia 20060101

Title: Effects of rupatadine vs placebo on allergen-induced symptoms in patients exposed to aeroallergens in the Vienna Challenge Chamber.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060101

Title: Neuroleptic malignant syndrome and serotonin syndrome in the critical care setting: case analysis.

Journal: Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20060101

Title: Rare case of serotonin syndrome with therapeutic doses of paroxetine.

Journal: American journal of therapeutics 20060101

Title: Antipruritic and antierythema effects of ascomycete Bulgaria inquinans extract in ICR Mice.

Journal: Biological & pharmaceutical bulletin 20051201

Title: Acute anticholinergic poisoning in children.

Journal: Hong Kong medical journal = Xianggang yi xue za zhi 20051201

Title: Pizotyline effectively attenuates the stimulus effects of N-methyl-3,4-methylenedioxyamphetamine (MDMA).

Journal: Pharmacology, biochemistry, and behavior 20051001

Title: Long-term trial of cyproheptadine as an appetite stimulant in cystic fibrosis.

Journal: Pediatric pulmonology 20050901

Title: Effects of drug treatment on inflammation and hyperreactivity of airways and on immune variables in cats with experimentally induced asthma.

Journal: American journal of veterinary research 20050701

Title: Intrathecal application of cyproheptadine impairs locomotion in intact rats.

Journal: Neuroscience letters 20050601

Title: Lethal, oedema, haemorrhagic activity of spotted butterfish (Scatophagus argus, Linn) sting extract and its neutralization by antiserum and pharmacological antagonists.

Journal: Indian journal of experimental biology 20050601

Title: The treatment of pediatric migraine.

Journal: Pediatric annals 20050601

Title: Pharmacological management of treatment-induced insomnia in ADHD.

Journal: Journal of the American Academy of Child and Adolescent Psychiatry 20050501

Title: Pharmacological investigation of the nociceptive response and edema induced by venom of the scorpion Tityus serrulatus.

Journal: Toxicon : official journal of the International Society on Toxinology 20050401

Title: Rupatadine 10 mg and cetirizine 10 mg in seasonal allergic rhinitis: a randomised, double-blind parallel study.

Journal: Journal of investigational allergology & clinical immunology 20050101

Title: 5-HT2 receptor mediated the potentiation of GABA-activated current in the membrane of the dorsal root ganglion neurons of rat.

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20050101

Title: 5-Hydroxytryptamine-2A receptor gene (HTR 2 A) candidate polymorphism (T 102 C): Role for human platelet function under pharmacological challenge ex vivo.

Journal: Methods and findings in experimental and clinical pharmacology 20050101

Title: Effect of cyproheptadine on serum leptin levels.

Journal: Advances in therapy 20050101

Title: [Studies for analyzing the prohibited ingredients such as cyproheptadine hydrochloride in cosmetics].

Journal: Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences 20050101

Title: Cyproheptadine's antiserotonin effects are responsible for its antimigraine activity.

Journal: Headache 20041001

Title: Antispasticity medications: uses and limitations of enteral therapy.

Journal: American journal of physical medicine & rehabilitation 20041001

Title: Cutting edge: serotonin is a chemotactic factor for eosinophils and functions additively with eotaxin.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20040915

Title: Effects of autacoid inhibitors and of an antagonist on malaria infection in mice.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20040801

Title: Pentacyclic triterpenoids, alpha,beta-amyrins, suppress the scratching behavior in a mouse model of pruritus.

Journal: Pharmacology, biochemistry, and behavior 20040801

Title: Evaluation of antipruritic effects of several agents on scratching behavior by NC/Nga mice.

Journal: European journal of pharmacology 20040714

Title: Rupatadine 10 mg and ebastine 10 mg in seasonal allergic rhinitis: a comparison study.

Journal: Allergy 20040701

Title: HPLC and chemometric methods for the simultaneous determination of cyproheptadine hydrochloride, multivitamins, and sorbic acid.

Journal: Journal of pharmaceutical and biomedical analysis 20040629

Title: Inhibition of insulin synthesis by cyproheptadine: effects on translation.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20040601

Title: Isolation of a haemorrhagic protein toxin (SA-HT) from the Indian venomous butterfish (Scatophagus argus, Linn) sting extract.

Journal: Indian journal of experimental biology 20040501

Title: Cyproheptadine in the treatment of autistic disorder: a double-blind placebo-controlled trial.

Journal: Journal of clinical pharmacy and therapeutics 20040401

Title: Serotonin modulates hypothalamic neuronal activity.

Journal: The International journal of neuroscience 20040301

Title: Prophylactic treatment of pediatric migraine.

Journal: Headache 20040301

Title: A comparison of the pharmacokinetics of oral and sublingual cyproheptadine.

Journal: Journal of toxicology. Clinical toxicology 20040101

Title: A randomized, double-blind, parallel-group study, comparing the efficacy and safety of rupatadine (20 and 10 mg), a new PAF and H1 receptor-specific histamine antagonist, to loratadine 10 mg in the treatment of seasonal allergic rhinitis.

Journal: Journal of investigational allergology & clinical immunology 20040101

Title: The use of antiserotonin drugs in the nucleoreticular vestibular syndrome: preliminary observations.

Journal: The international tinnitus journal 20040101

Title: Central and peripheral evaluation of rupatadine, a new antihistamine/platelet-activating factor antagonist, at different doses in healthy volunteers.

Journal: Neuropsychobiology 20040101

Title: Nelson's syndrome: complete remission with cabergoline but not with bromocriptine or cyproheptadine treatment.

Journal: Hormone research 20040101

Title: Serotonin syndrome induced by a combination of bupropion and SSRIs.

Journal: Clinical neuropharmacology 20040101

Title: The effects of 5-HT on feeding behaviour in mianserin- or cyproheptadine-pretreated rats.

Journal: Eating and weight disorders : EWD 20031201

Title: Olanzapine reduces craving for alcohol: a DRD4 VNTR polymorphism by pharmacotherapy interaction.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20031001

Title: Pharmacological characterization of mouse hind paw oedema induced by Bothrops insularis (jararaca ilhoa) snake venom.

Journal: Toxicon : official journal of the International Society on Toxinology 20031001

Title: Synergism interaction between arachidonic acid by 5-hydroxytryptamine in human platelet aggregation is mediated through multiple signalling pathways.

Journal: Acta pharmacologica Sinica 20031001

Title: Serotonergic and histaminergic mechanisms involved in intralipid drinking?

Journal: Pharmacology, biochemistry, and behavior 20030901

Title: Differential regulation of rat peripheral 5-HT(2A) and 5-HT(2B) receptor systems: influence of drug treatment.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20030801

Title: Cyproheptadine and the treatment of an unconscious patient with the serotonin syndrome.

Journal: European journal of anaesthesiology 20030701

Title: Antinociceptive mechanisms of orally administered decursinol in the mouse.

Journal: Life sciences 20030613

Title: Evaluation of tricyclic antidepressant false positivity in a pediatric case of cyproheptadine (periactin) overdose.

Journal: Therapeutic drug monitoring 20030601

Title: Rupatadine: a new selective histamine H1 receptor and platelet-activating factor (PAF) antagonist. A review of pharmacological profile and clinical management of allergic rhinitis.

Journal: Drugs of today (Barcelona, Spain : 1998) 20030601

Title: Anorexia nervosa.

Journal: Clinical evidence 20030601

Title: Cyproheptadine for intrathecal baclofen withdrawal.

Journal: Archives of physical medicine and rehabilitation 20030501

Title: Paroxetine as a 5-HT neuroendocrine probe.

Journal: Psychopharmacology 20030401

Title: Episodic spontaneous hypothermia: a periodic childhood syndrome.

Journal: Pediatric neurology 20030401

Title: Pharmacological characterization of an adenylyl cyclase-coupled 5-HT receptor in aplysia: comparison with mammalian 5-HT receptors.

Journal: Journal of neurophysiology 20030301

Title: Replacement therapy in Mucopolysaccharidosis type VI: advantages of early onset of therapy.

Journal: Molecular genetics and metabolism 20030301

Title: Combined action of vasoactive amines and bradykinin mediates allergen-evoked thermal hyperalgesia in rats.

Journal: European journal of pharmacology 20030221

Title: LC-MS and NMR determination of a dichloromethane artifact adduct, cyproheptadine chloromethochloride.

Journal: Journal of pharmaceutical and biomedical analysis 20030205

Title: Reversal of iron deficiency anemia in a patient with gastric antral vascular ectasia treated with cyproheptadine.

Journal: Journal of clinical gastroenterology 20030201

Title: Pediatric nonenvironmental hypothermia presenting to the emergency department: Episodic spontaneous hypothermia with hyperhidrosis.

Journal: Pediatric emergency care 20030201

Title: Localization of serotonin and its possible role in early embryos of Tritonia diomedea(Mollusca: Nudibranchia).

Journal: Cell and tissue research 20030201

Title: Cardiac Ca(2+) channel-blocking effects of the cyproheptadine derivative AH-1058 in isolated guinea pig cardiomyocytes.

Journal: Journal of pharmacological sciences 20030201

Title: Tricyclic analogs cyclobenzaprine, amitriptyline and cyproheptadine inhibit the spinal reflex transmission through 5-HT(2) receptors.

Journal: European journal of pharmacology 20030101

Title: [Serotonin syndrome].

Journal: Ryoikibetsu shokogun shirizu 20030101

Title: Hornet sting induced systemic allergic reaction and large local reaction with bulle formation and rhabdomyolysis.

Journal: Journal of toxicology. Clinical toxicology 20030101

Title: Medical treatment of hyperadrenocorticism in the dog.

Journal: Australian veterinary journal 20030101

Title: Haem polymerase as a novel target of antimalarial action of cyproheptadine.

Journal: Biochemical pharmacology 20021101

Title: [MRI findings and effectiveness of cyproheptadine in two patients with ophthalmoplegic migraine].

Journal: No to hattatsu = Brain and development 20021101

Title: Plasma adrenocorticotropin (ACTH) concentrations and clinical response in horses treated for equine Cushing's disease with cyproheptadine or pergolide.

Journal: Equine veterinary journal 20021101

Title: The role of nutrition in the regulation of LH secretion during anestrus by the serotoninergic and dopaminergic systems in Mediterranean ewes treated with melatonin.

Journal: Theriogenology 20021015

Title: Possible role of mast cells in cineole-induced scratching behavior in mice.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20021001

Title: 5-HT2A and 5-HT2C serotonin receptors differentially modulate mouse sexual arousal and the hypothalamo-pituitary-testicular response to the presence of a female.

Journal: Neuroendocrinology 20020701

Title: Cyproheptadine in treatment of autism.

Journal: European psychiatry : the journal of the Association of European Psychiatrists 20020701

Title: Serotonin excites arcuate neurons directly but inhibits them through intercalated GABAergic neurons.

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20020625

Title: Cyproheptadine for drug-induced sweating.

Journal: The American journal of psychiatry 20020501

Title: Functional characterization of serotonin receptors in rat isolated aorta.

Journal: Biological & pharmaceutical bulletin 20020501

Title: Identification of C3a and N-truncated C3a as vascular permeability-enhancing factors from the exudate of chronic phase of carrageenan-induced inflammation in rats.

Journal: Biological & pharmaceutical bulletin 20020501

Title: Role of S2 receptors in the stimulatory effect of serotonin on hemopoietic bone marrow stem cells.

Journal: Bulletin of experimental biology and medicine 20020501

Title: Anti-inflammatory triterpenes from Pistacia terebinthus galls.

Journal: Planta medica 20020401

Title: Is the 5-HT(7) receptor involved in the pathogenesis and prophylactic treatment of migraine?

Journal: European journal of pharmacology 20020329

Title: Anti-endotoxic shock effects of cyproheptadine in rats.

Journal: Chinese medical journal 20020301

Title: Anti-CD44 monoclonal antibody (IM7) induces murine systemic shock mediated by platelet activating factor.

Journal: Journal of autoimmunity 20020201

Title: Effects of the 5HT antagonist cyproheptadine on neuropsychological function in chronic schizophrenia.

Journal: Schizophrenia research 20020101

Title: Abdominal migraine: evidence for existence and treatment options.

Journal: Paediatric drugs 20020101

Title: Assessment of spinal cord pathology following trauma using early changes in the spinal cord evoked potentials: a pharmacological and morphological study in the rat.

Journal: Muscle & nerve. Supplement 20020101

Title: The central role of thromboxane and platelet activating factor receptors in ex vivo regulation of endotoxin-induced monocyte tissue factor activity in human whole blood.

Journal: Journal of endotoxin research 20020101

Title: Dimorphic exanthema manifested as reticular maculopapular exanthema and erythema multiforme major associated with pyrazolon derivatives.

Journal: European journal of dermatology : EJD 20020101

Title: Treatment with pergolide or cyproheptadine of pituitary pars intermedia dysfunction (equine Cushing's disease).

Journal: Journal of veterinary internal medicine 20020101

Title: Cyproheptadine versus propranolol for the treatment of acute neuroleptic-induced akathisia: a comparative double-blind study.

Journal: Journal of clinical psychopharmacology 20011201

Title: Comment: serotonin syndrome, mydriasis, and cyproheptadine.

Journal: The Annals of pharmacotherapy 20011201

Title: Alpha adrenergic and serotonergic agents in the treatment of spastic hypertonia.

Journal: Physical medicine and rehabilitation clinics of North America 20011101

Title: Second messengers in platelet aggregation evoked by serotonin and A23187, a calcium ionophore.

Journal: Life sciences 20011026

Title: Verapamil, cyproheptadine, and anisodamine antagonized [Ca2+]i elevation induced by TNFalpha in a single endothelial cell.

Journal: Acta pharmacologica Sinica 20011001

Title: Effects of type 1A serotonin receptor agonist 8-OH-DPAT on immune response.

Journal: Bulletin of experimental biology and medicine 20011001

Title: Effects of cyproheptadine clorhydrate, a serotonin receptor antagonist, on endocrine parameters in weight-loss related amenorrhea.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20010801

Title: Serotonin-based pharmacotherapy for acute neuroleptic-induced akathisia: a new approach to an old problem.

Journal: The British journal of psychiatry : the journal of mental science 20010701

Title: Effects of the serotonin receptor antagonist cyproheptadine on the activity and pharmacokinetics of 5,6-dimethylxanthenone-4-acetic acid (DMXAA).

Journal: Cancer chemotherapy and pharmacology 20010601

Title: A difference between the rat and mouse in the pharmacokinetic interaction of 5,6-dimethylxanthenone-4-acetic acid with thalidomide.

Journal: Cancer chemotherapy and pharmacology 20010601

Title: Low-dose citalopram as a 5-HT neuroendocrine probe.

Journal: Psychopharmacology 20010501

Title: An update: cancer-associated anorexia as a treatment target.

Journal: Current opinion in clinical nutrition and metabolic care 20010501

Title: Effects of two newly synthesized analogues of lidocaine on rat arterial blood pressure and heart rate.

Journal: Pharmacological research 20010401

Title: Exploring the relationship between binding modes of 9-(aminomethyl)-9,10-dihydroanthracene and cyproheptadine analogues at the 5-HT2A serotonin receptor.

Journal: Bioorganic & medicinal chemistry letters 20010226

Title: Potent serotonin (5-HT)(2A) receptor antagonists completely prevent the development of hyperthermia in an animal model of the 5-HT syndrome.

Journal: Brain research 20010126

Title: Role of the central nervous system in hemopoiesis regulation during experimental neuroses.

Journal: Bulletin of experimental biology and medicine 20010101

Title: Serotonin syndrome: early management with cyproheptadine.

Journal: The Annals of pharmacotherapy 20010101

Title: Effect of ondansetron on the contractile responses to positive inotropic agents in electrically driven left atria of rats.

Journal: Journal of basic and clinical physiology and pharmacology 20010101

Title: Effects of serotoninergic drugs on tremor induced by physostigmine in rats.

Journal: Behavioural brain research 20000501

Title: [Psychotic syndrome after withdrawal of cyproheptadine: remission with olanzapine].

Journal: Actas espanolas de psiquiatria 20000101

Title: Case study: cyproheptadine and aggression in a five-year-old boy.

Journal: Journal of the American Academy of Child and Adolescent Psychiatry 19980601

Title: Fungal biotransformation of the antihistamine azatadine by Cunninghamella elegans.

Journal: Applied and environmental microbiology 19960901

Title: Relapse following clozapine withdrawal: effect of neuroleptic drugs and cyproheptadine.

Journal: Psychopharmacology 19960301

Title: Successful treatment of citalopram-induced anorgasmia by cyproheptadine.

Journal: Acta psychiatrica Scandinavica 19960101

Title: Cyproheptadine treatment of sexual dysfunction induced by serotonin reuptake inhibitors.

Journal: Clinical neuropharmacology 19950801

Title: [Arterial hypertension in Cushing's disease: the 24-hour pressure profile without and during treatment with beta-blockers or cyproheptadine].

Journal: Giornale italiano di cardiologia 19940501

Title: [Acute urine retention: a rare mode of revelation of cervico-dorsal syringomyelia caused by cyproheptadine].

Journal: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 19940301

Title: Profile of capsaicin-induced mouse ear oedema as neurogenic inflammatory model: comparison with arachidonic acid-induced ear oedema.

Journal: British journal of pharmacology 19931201

Title: The effect of antihistamines on the immediate allergic response: a comparative review.

Journal: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 19930601

Title: Depression after cyproheptadine: MAO treatment.

Journal: Biological psychiatry 19920601

Title: Fluoxetine-induced yawning and anorgasmia reversed by cyproheptadine treatment.

Journal: The Journal of clinical psychiatry 19920501

Title: Reversal of antidepressant activity of fluoxetine by cyproheptadine in three patients.

Journal: The Journal of clinical psychiatry 19910401

Title: Comparative effects of loratadine and azatadine in the treatment of seasonal allergic rhinitis.

Journal: Asian Pacific journal of allergy and immunology 19901201

Title: Reversal of fluoxetine-induced anorgasmia by cyproheptadine in two patients.

Journal: The Journal of clinical psychiatry 19900901

Title: Effects of azatadine, terfenadine, and astemizole on allergen-induced nasal provocation.

Journal: Annals of allergy 19900201

Title: A characterization of the acute cardiopulmonary toxicity of fenfluramine in the rat.

Journal: Pharmacological research 19900101

Title: Choreoathetosis induced by cyproheptadine.

Journal: Movement disorders : official journal of the Movement Disorder Society 19890101

Title: Successful treatment of levodopa-induced myoclonus and levodopa withdrawal-induced neuroleptic malignant syndrome. A case report.

Journal: Clinical neuropharmacology 19880601

Title: [Hepatitis caused by cyproheptadine (Periactine). A case and review of the literature].

Journal: Gastroenterologie clinique et biologique 19880101

Title: Possible toxic interaction between cyproheptadine and phenelzine.

Journal: The American journal of psychiatry 19870901

Title: Treatment of lethal pertussis vaccine reaction with histamine H1 antagonists.

Journal: Neurology 19870601

Title: Prolonged cholestasis after cyproheptadine-induced acute hepatitis.

Journal: Journal of clinical gastroenterology 19870201

Title: Pseudoephedrine-induced hypertensive emergency: treatment with labetalol.

Journal: The American journal of emergency medicine 19860301

Title: Demonstration of inhibition of mediator release from human mast cells by azatadine base. In vivo and in vitro evaluation.

Journal: JAMA 19860110

Title: Peripheral antihistamine and central sedative effects of three H1-receptor antagonists.

Journal: European journal of clinical pharmacology 19850101

Title: Clinical pharmacokinetics of H1-receptor antagonists (the antihistamines).

Journal: Clinical pharmacokinetics 19850101

Title: Prolonged remission of Cushing disease after treatment with cyproheptadine.

Journal: The Journal of pediatrics 19840601

Title: Chlorpromazine methiodide acts at the vestibular nuclear complex to induce barrel rotation in the rat.

Journal: Brain research 19831212

Title: Treatment of valproate tremors.

Journal: Neurology 19831001

Title: [Effect of lysyl vasopressin and vasotocin on a disorder of the conditioned avoidance reaction by a serotonin receptor blockader].

Journal: Biulleten' eksperimental'noi biologii i meditsiny 19830201

Title: Neuropharmacology of the parasitic trematode, Schistosoma mansoni.

Journal: The American journal of tropical medicine and hygiene 19830101

Title: Opposite effects of chlordiazepoxide and serotonin receptor antagonists on morphine-induced locomotor stimulation in mice.

Journal: Psychopharmacology 19820101

Title: Sustained remission of Nelson's syndrome after stopping cyproheptadine treatment.

Journal: The New England journal of medicine 19800221

Title: Jaundice during cyproheptadine treatment.

Journal: British medical journal 19780325

Title: [Toxicity of cyproheptadine. Side effects and accidental overdosage (author's transl)].

Journal: Monatsschrift fur Kinderheilkunde 19780301

Title: Cyproheptadine in levodopa-induced dyskinesia in parkinsonism.

Journal: Clinical pharmacology and therapeutics 19780201

Title: Treatment of Cushing's disease with cyproheptadine.

Journal: Lancet (London, England) 19770625

Title: Toxic psychosis due to cyproheptadine in a child on hemodialysis: a case report.

Journal: Clinical nephrology 19770101

Title: Differentiaton of neuropharmacological actions of apomorphine and d-amphetamine.

Journal: Pharmacology, biochemistry, and behavior 19761201

Title: On the anticataleptic action of cyproheptadine.

Journal: Pharmacology, biochemistry, and behavior 19760801

Title: Antagonistic effect of cyproheptadine on neuroleptic-induced catalepsy.

Journal: Pharmacology, biochemistry, and behavior 19750101

Title: Suppression of the drug-induced morphine withdrawal syndrome by cyproheptadine.

Journal: Psychopharmacologia 19730101

Title: Comparative trial of serotonin antagonists in the management of migraine.

Journal: British medical journal 19700509

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:41354-29-4 Molecular Formula|41354-29-4 MDL|41354-29-4 SMILES|41354-29-4 Cyproheptadine hydrochloride sesquihydrate