Home Amines 41621-49-2
41621-49-2,MFCD00078997
Catalog No.:AA0071KG

41621-49-2 | 2-aminoethan-1-ol; 6-cyclohexyl-1-hydroxy-4-methyl-1,2-dihydropyridin-2-one

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1g
98%(HPLC)
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$24.00   $17.00
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5g
97%
in stock  
$37.00   $26.00
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25g
97%
in stock  
$103.00   $73.00
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100g
97%
in stock  
$286.00   $200.00
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500g
97%
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$992.00   $695.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0071KG
Chemical Name:
2-aminoethan-1-ol; 6-cyclohexyl-1-hydroxy-4-methyl-1,2-dihydropyridin-2-one
CAS Number:
41621-49-2
Molecular Formula:
C14H24N2O3
Molecular Weight:
268.3520
MDL Number:
MFCD00078997
SMILES:
Cc1cc(C2CCCCC2)n(c(=O)c1)O.NCCO
Properties
Computed Properties
 
Complexity:
335  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
2  

Literature

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Journal: Mycopathologia 20121001

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Title: Competitive displacement of drugs from cyclodextrin inclusion complex by polypseudorotaxane formation with poloxamer: implications in drug solubilization and delivery.

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Title: Effect of pH on in vitro susceptibility of Candida glabrata and Candida albicans to 11 antifungal agents and implications for clinical use.

Journal: Antimicrobial agents and chemotherapy 20120301

Title: Design, synthesis of some new (2-aminothiazol-4-yl)methylester derivatives as possible antimicrobial and antitubercular agents.

Journal: European journal of medicinal chemistry 20120301

Title: Comparative clinical evaluation of efficacy and safety of a formulation containing ciclopirox 8% in the form of a therapeutic nail lacquer in two different posologies for the treatment of onychomycosis of the toes.

Journal: Anais brasileiros de dermatologia 20120101

Title: Wnt inhibitor screen reveals iron dependence of β-catenin signaling in cancers.

Journal: Cancer research 20111215

Title: Recurrent vulvovaginal candidosis: focus on the vulva.

Journal: Mycoses 20111101

Title: Standardization of hyphal growth inhibition rate as a means of evaluating Microsporum spp. in vitro susceptibility to terbinafine, griseofulvin, and ciclopiroxolamine.

Journal: Mycopathologia 20111001

Title: Rescue of the mutant CFTR chloride channel by pharmacological correctors and low temperature analyzed by gene expression profiling.

Journal: American journal of physiology. Cell physiology 20111001

Title: Tinea capitis in an adult patient under treatment with trastuzumab.

Journal: Mycoses 20110901

Title: In vivo efficacy of griseofulvin against multiple myeloma.

Journal: Leukemia research 20110801

Title: Validation of bovine hoof slices as a model for infected human toenails: in vitro ciclopirox transungual permeation.

Journal: The British journal of dermatology 20110701

Title: The fungicide ciclopirox inhibits lymphatic endothelial cell tube formation by suppressing VEGFR-3-mediated ERK signaling pathway.

Journal: Oncogene 20110505

Title: Multipotent adult germline stem cells and embryonic stem cells functional proteomics revealed an important role of eukaryotic initiation factor 5A (Eif5a) in stem cell differentiation.

Journal: Journal of proteome research 20110401

Title: The repositioning of the anti-fungal agent ciclopirox olamine as a novel therapeutic agent for the treatment of haematologic malignancy.

Journal: Journal of clinical pharmacy and therapeutics 20110401

Title: Determination of ciclopirox olamine in pharmaceutical products by capillary electrophoresis with capacitively coupled contactless conductivity detection.

Journal: Electrophoresis 20110401

Title: Cyclosporin A inhibits hepatitis C virus replication and restores interferon-alpha expression in hepatocytes.

Journal: Transplant infectious disease : an official journal of the Transplantation Society 20110201

Title: Microsporum praecox: molecular identification of a new case and review of the literature.

Journal: Mycopathologia 20110101

Title: Targeting the Wnt/beta-catenin pathway with the antifungal agent ciclopirox olamine in a murine myeloma model.

Journal: In vivo (Athens, Greece) 20110101

Title: Antimycotic ciclopirox olamine in the diabetic environment promotes angiogenesis and enhances wound healing.

Journal: PloS one 20110101

Title: The antitumor activity of the fungicide ciclopirox.

Journal: International journal of cancer 20101115

Title: Ciclopirox: recent nonclinical and clinical data relevant to its use as a topical antimycotic agent.

Journal: Drugs 20101112

Title: Widespread erosive tinea corporis by Arthroderma benhamiae in a renal transplant recipient: case report.

Journal: Mycoses 20101101

Title: First case of Trichophyton soudanense isolated in Tunisia.

Journal: Mycopathologia 20101101

Title: Synthesis and biological evaluation of some 1,3,4-oxadiazole derivatives.

Journal: European journal of medicinal chemistry 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Ciclopirox olamine: an antifungal alternative against cryptococcosis.

Journal: Letters in applied microbiology 20101101

Title: Design, synthesis and antimicrobial activities of some new quinoline derivatives carrying 1,2,3-triazole moiety.

Journal: European journal of medicinal chemistry 20100901

Title: Studies on nonionic surfactant bilayer vesicles of ciclopirox olamine.

Journal: Drug development and industrial pharmacy 20100801

Title: Hypoxia-inducible factor-1 improves inotropic responses of cardiac myocytes in ageing heart without affecting mitochondrial activity.

Journal: Experimental physiology 20100601

Title: Effect of a novel penetration enhancer on the ungual permeation of two antifungal agents.

Journal: The Journal of pharmacy and pharmacology 20100601

Title: Antifungal activity, experimental infections and nail permeation of an innovative ciclopirox nail lacquer based on a water-soluble biopolymer.

Journal: Journal of drugs in dermatology : JDD 20100501

Title: [Melanonychia: The purpose of a case of ungual mycotization mimicking melanoma].

Journal: Dermatology online journal 20100315

Title: Onychomycosis.

Journal: Clinics in dermatology 20100304

Title: Synthesis and antimicrobial activities of novel 1,5-diaryl pyrazoles.

Journal: European journal of medicinal chemistry 20100301

Title: Hydrosoluble medicated nail lacquers: in vitro drug permeation and corresponding antimycotic activity.

Journal: The British journal of dermatology 20100201

Title: Ciclopirox nail lacquer for the treatment of onychomycosis: an open non-comparative study.

Journal: The Journal of dermatology 20100201

Title: A direct LC/MS/MS method for the determination of ciclopirox penetration across human nail plate in in vitro penetration studies.

Journal: Journal of pharmaceutical and biomedical analysis 20100105

Title: A randomized, double-blind study comparing the efficacy of selenium sulfide shampoo 1% and ciclopirox shampoo 1% as adjunctive treatments for tinea capitis in children.

Journal: Pediatric dermatology 20100101

Title: Randomized study comparing the efficacy and tolerance of a lipohydroxy acid shampoo to a ciclopiroxolamine shampoo in the treatment of scalp seborrheic dermatitis.

Journal: Journal of cosmetic dermatology 20091201

Title: Susceptibility testing of amorolfine, bifonazole and ciclopiroxolamine against Trichophyton rubrum in an in vitro model of dermatophyte nail infection.

Journal: Medical mycology 20091101

Title: The human urocortin 2 gene is regulated by hypoxia: identification of a hypoxia-responsive element in the 3'-flanking region.

Journal: The Biochemical journal 20091023

Title: Iontophoretically enhanced ciclopirox delivery into and across human nail plate.

Journal: Journal of pharmaceutical sciences 20091001

Title: Onychomycosis and diabetes.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20091001

Title: Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells.

Journal: Blood 20091001

Title: By the way, doctor. Penlac didn't work to cure my toenail fungus. I took an oral medication, terbinafine, and saw some improvement, but my insurance company won't approve more than a few months of treatment. It's frustrating to finally have a solution and then be cut off.

Journal: Harvard health letter 20091001

Title: Hypoxia inducible factor-1 improves the actions of positive inotropic agents in stunned cardiac myocytes.

Journal: Clinical and experimental pharmacology & physiology 20090901

Title: Bullous ulcerating tinea.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20090701

Title: An innovative water-soluble biopolymer improves efficacy of ciclopirox nail lacquer in the management of onychomycosis.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20090701

Title: The use of oral terbinafine or topical ciclopirox for lichen planus.

Journal: Cutis 20090701

Title: Clinical practice. Fungal nail disease.

Journal: The New England journal of medicine 20090514

Title: Non-hypoxic stabilization of hypoxia-inducible factor alpha (HIF-alpha): relevance in neural progenitor/stem cells.

Journal: Neurotoxicity research 20090501

Title: Targeting Wnt pathway in lymphoma and myeloma cells.

Journal: British journal of haematology 20090301

Title: Synthesis and antimicrobial activities of some new triazolothiadiazoles bearing 4-methylthiobenzyl moiety.

Journal: European journal of medicinal chemistry 20090201

Title: Determination of the efficacy of terbinafine hydrochloride nail solution in the topical treatment of dermatophytosis in a guinea pig model.

Journal: Mycoses 20090101

Title: Nail infection by Aspergillus ochraceopetaliformis.

Journal: Medical mycology 20090101

Title: Efficacy of debridement alone versus debridement combined with topical antifungal nail lacquer for the treatment of pedal onychomycosis: a randomized, controlled trial.

Journal: The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons 20090101

Title: Toenail onychomycosis in diabetic patients: issues and management.

Journal: American journal of clinical dermatology 20090101

Title: Inhibition of HIV-1 gene expression by Ciclopirox and Deferiprone, drugs that prevent hypusination of eukaryotic initiation factor 5A.

Journal: Retrovirology 20090101

Title: Evaluation of a nonsteroidal topical cream in a guinea pig model of Malassezia furfur infection.

Journal: Clinics in dermatology 20090101

Title: Onychomycosis in a very young child.

Journal: Pediatric dermatology 20090101

Title: Ototoxic effect of topical ciclopirox as an antimycotic preparation.

Journal: Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20081001

Title: Antimicrobial activity of iodoquinol 1%-hydrocortisone acetate 2% gel against ciclopirox and clotrimazole.

Journal: Cutis 20081001

Title: Fast and simple method for assay of ciclopirox olamine by micellar electrokinetic capillary chromatography.

Journal: Journal of pharmaceutical and biomedical analysis 20080805

Title: In vitro antifungal activity of sertaconazole nitrate against recent isolates of onychomycosis causative agents.

Journal: Journal of chemotherapy (Florence, Italy) 20080801

Title: Preanalytical conditions for broth microdilution antifungal susceptibility of Microsporum spp.

Journal: Mycoses 20080701

Title: Contact allergy to topical antifungal agents.

Journal: Allergy 20080701

Title: Synthesis, antimicrobial and anti-inflammatory activities of some 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles and 1,2,4-triazolo[3,4-b][1,3,4]thiadiazines bearing trichlorophenyl moiety.

Journal: European journal of medicinal chemistry 20080401

Title: Synthesis of some novel 2,4-disubstituted thiazoles as possible antimicrobial agents.

Journal: European journal of medicinal chemistry 20080201

Title: In search of novel agents for therapy of tropical diseases and human immunodeficiency virus.

Journal: Journal of medicinal chemistry 20080124

Title: Ciclopirox olamine directly scavenges hydroxyl radical.

Journal: International journal of dermatology 20080101

Title: Tinea incognito hidden under apparently treatment-resistant pemphigus foliaceus.

Journal: Acta dermato-venereologica 20080101

Title: Effects of VEGF on the blood-brain barrier disruption caused by hyperosmolarity.

Journal: Pharmacology 20080101

Title: In Vitro penetration of a novel oxaborole antifungal (AN2690) into the human nail plate.

Journal: Journal of pharmaceutical sciences 20071001

Title: [Mucoadhesive tablets for oral administration of ciclopiroxolamine].

Journal: Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20071001

Title: Convenient one pot synthesis and antimicrobial evaluation of some new Mannich bases carrying 4-methylthiobenzyl moiety.

Journal: European journal of medicinal chemistry 20070801

Title: Identification and in vitro antifungal susceptibility testing of 200 clinical isolates of Candida spp. responsible for fingernail infections.

Journal: Mycopathologia 20070701

Title: Trichophytic Majocchi granuloma mimicking Kaposi sarcoma.

Journal: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20070701

Title: An atypical active cell death process underlies the fungicidal activity of ciclopirox olamine against the yeast Saccharomyces cerevisiae.

Journal: FEMS yeast research 20070501

Title: Inhibitory or scavenging action of ketoconazole and ciclopiroxolamine against reactive oxygen species released by primed inflammatory cells.

Journal: The British journal of dermatology 20070401

Title: Toenail onychomycosis: current and future treatment options.

Journal: Dermatologic therapy 20070101

Title: Ciclopirox 8% nail lacquer topical solution for the treatment of onychomycosis in patients with diabetes: a multicenter, open-label study.

Journal: Journal of the American Podiatric Medical Association 20070101

Title: Clinical efficacies of shampoos containing ciclopirox olamine (1.5%) and ketoconazole (2.0%) in the treatment of seborrhoeic dermatitis.

Journal: The Journal of dermatological treatment 20070101

Title: An open randomized comparative study to test the efficacy and safety of oral terbinafine pulse as a monotherapy and in combination with topical ciclopirox olamine 8% or topical amorolfine hydrochloride 5% in the treatment of onychomycosis.

Journal: Indian journal of dermatology, venereology and leprology 20070101

Title: Malassezia furfur onychomycosis in an immunosuppressed liver transplant recipient.

Journal: Indian journal of dermatology, venereology and leprology 20070101

Title: In vitro antifungal efficacy of ciclopirox olamine alone and associated with zinc pyrithione compared to ketoconazole against Malassezia globosa and Malassezia restricta reference strains.

Journal: Mycopathologia 20061201

Title: Majocchi's granuloma after kidney transplantation.

Journal: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20061201

Title: [Bilateral proximal cellulitis and onychomycosis in both big toes due to Fusarium solani].

Journal: Revista iberoamericana de micologia 20061201

Title: Spectrofluorimetric determination of ciclopirox olamine via ternary complex with Tb(III) and EDTA.

Journal: Acta pharmaceutica (Zagreb, Croatia) 20061201

Title: Piperidones with activity against Plasmodium falciparum.

Journal: Parasitology research 20060801

Title: Dystrophic onychomycosis due to Microsporum gypseum.

Journal: Mycoses 20060701

Title: Contact dermatitis due to ciclopiroxolamine.

Journal: Mycoses 20060701

Title: Different physicochemical properties of antimycotic agents are relevant for penetration into and through human nails.

Journal: Die Pharmazie 20060701

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Antimycotic influence of beta-cyclodextrin complexes--in vitro measurements using laser nephelometry in microtiter plates.

Journal: International journal of pharmaceutics 20060327

Title: Congenital candidal onychomycoses: effective cure with ciclopirox olamine 8% nail lacquer.

Journal: The British journal of dermatology 20060301

Title: Ciclopirox 1% shampoo for the treatment of seborrheic dermatitis.

Journal: International journal of dermatology 20060101

Title: Treatment of head and neck dermatitis with ciclopiroxolamine cream--results of a double-blind, placebo-controlled study.

Journal: Skin pharmacology and physiology 20060101

Title: Rapid treatment of tinea nigra palmaris with ciclopirox olamine gel, 0.77%.

Journal: Skinmed 20060101

Title: Clinical efficacy of a new ciclopiroxolamine/zinc pyrithione shampoo in scalp seborrheic dermatitis treatment.

Journal: European journal of dermatology : EJD 20060101

Title: A-Detail fact sheet (Canada). Ciclopirox 8% nail lacquer (Penlac).

Journal: Skin therapy letter 20051201

Title: Ciclopirox nail lacquer 8% for the treatment of onychomycosis: a Canadian perspective.

Journal: Skin therapy letter 20050901

Title: Evaluation of the efficacy of ciclopirox 0.77% gel in the treatment of tinea pedis interdigitalis (dermatophytosis complex) in a randomized, double-blind, placebo-controlled trial.

Journal: International journal of dermatology 20050701

Title: Ciclopirox protects mitochondria from hydrogen peroxide toxicity.

Journal: British journal of pharmacology 20050601

Title: Can the use of a topical antifungal nail lacquer reduce risk for diabetic foot ulceration? Results from a randomised controlled pilot study.

Journal: International wound journal 20050601

Title: Oxygen accessibility and iron levels are critical factors for the antifungal action of ciclopirox against Candida albicans.

Journal: The Journal of antimicrobial chemotherapy 20050501

Title: Genome-wide expression profiling of the response to ciclopirox olamine in Candida albicans.

Journal: The Journal of antimicrobial chemotherapy 20050501

Title: The safety and efficacy of ciclopirox olamine for the treatment of seborrheic dermatitis.

Journal: Expert opinion on drug safety 20050301

Title: Physicochemical studies on Ciclopirox olamine complexes with divalent metal ions.

Journal: International journal of pharmaceutics 20050131

Title: Topical antifungal drugs for the treatment of onychomycosis: an overview of current strategies for monotherapy and combination therapy.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20050101

Title: Treatment and prophylaxis of seborrheic dermatitis of the scalp with antipityrosporal 1% ciclopirox shampoo.

Journal: Archives of dermatology 20050101

Title: A multicenter, open-label study to assess the safety and efficacy of ciclopirox topical suspension 0.77% in the treatment of diaper dermatitis due to Candida albicans.

Journal: Journal of drugs in dermatology : JDD 20050101

Title: In vitro transungual permeation of ciclopirox from a hydroxypropyl chitosan-based, water-soluble nail lacquer.

Journal: Drug development and industrial pharmacy 20050101

Title: Ciclopirox topical solution, 8% combined with oral terbinafine to treat onychomycosis: a randomized, evaluator-blinded study.

Journal: Journal of drugs in dermatology : JDD 20050101

Title: Treatment costs of three nail lacquers used in onychomycosis.

Journal: The Journal of dermatological treatment 20050101

Title: Combination of oral terbinafine and topical ciclopirox compared to oral terbinafine for the treatment of onychomycosis.

Journal: The Journal of dermatological treatment 20050101

Title: Cutaneous adiaspiromycosis: a distinct dermatologic entity associated with Chrysosporium species.

Journal: Journal of the American Academy of Dermatology 20041101

Title: Ciclopirox delivery into the human nail plate.

Journal: Journal of pharmaceutical sciences 20041001

Title: Management of onychomycosis with topicals.

Journal: Clinics in podiatric medicine and surgery 20041001

Title: Cell cycle arrest at the initiation step of human chromosomal DNA replication causes DNA damage.

Journal: Journal of cell science 20041001

Title: Ciclopirox: a broad-spectrum antifungal with antibacterial and anti-inflammatory properties.

Journal: International journal of dermatology 20040701

Title: Efficacy of different concentrations of ciclopirox shampoo for the treatment of seborrheic dermatitis of the scalp: results of a randomized, double-blind, vehicle-controlled trial.

Journal: International journal of dermatology 20040701

Title: Rationale of frequency of use of ciclopirox 1% shampoo in the treatment of seborrheic dermatitis: results of a double-blind, placebo-controlled study comparing the efficacy of once, twice, and three times weekly usage.

Journal: International journal of dermatology 20040701

Title: Safety and efficacy of ciclopirox 1% shampoo for the treatment of seborrheic dermatitis of the scalp in the US population: results of a double-blind, vehicle-controlled trial.

Journal: International journal of dermatology 20040701

Title: Activation of HIF-1alpha mRNA by hypoxia and iron chelator in isolated rat carotid body.

Journal: Neuroscience letters 20040617

Title: Tinea capitis favosa in Poland.

Journal: Mycoses 20040601

Title: The use of 40% urea cream in the treatment of moccasin tinea pedis.

Journal: Cutis 20040501

Title: [Onychomycosis].

Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20040201

Title: Fungus-free versus disease-free nails.

Journal: Journal of the American Academy of Dermatology 20040101

Title: Dermacase. Pityriasis rosea.

Journal: Canadian family physician Medecin de famille canadien 20040101

Title: Managing simple chronic paronychia and onycholysis with ciclopirox 0.77% and an irritant-avoidance regimen.

Journal: Cutis 20040101

Title: Assessing treatment outcomes in toenail onychomycosis clinical trials.

Journal: American journal of clinical dermatology 20040101

Title: Ciclopirox (Loprox) gel for superficial fungal infections.

Journal: Skin therapy letter 20040101

Title: Ciclopirox shampoo for treating seborrheic dermatitis.

Journal: Skin therapy letter 20040101

Title: A randomized comparison of nail surface remanence of three nail lacquers, containing amorolfine 5%, ciclopirox 8% or tioconazole 28%, in healthy volunteers.

Journal: International journal of tissue reactions 20040101

Title: Polarographic determination of ciclopirox olamine in pure substance and in different pharmaceutical preparations.

Journal: Farmaco (Societa chimica italiana : 1989) 20031201

Title: Action mechanisms of modern antifungal agents and resulting problems in the management of onychomycosis.

Journal: Mycoses 20031201

Title: Successful treatment of dandruff with 1.5% ciclopirox olamine shampoo in Korea.

Journal: The Journal of dermatological treatment 20031201

Title: Permeation of ciclopirox across porcine hoof membrane: effect of pressure sensitive adhesives and vehicles.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20031101

Title: Effects of hypoxia and intracellular iron chelation on hypoxia-inducible factor-1alpha and -1beta in the rat carotid body and glomus cells.

Journal: Histochemistry and cell biology 20031101

Title: I've heard there's a nail polish for nail fungus. Does it work?

Journal: Mayo Clinic women's healthsource 20031001

Title: Ciclopirox gel: an update.

Journal: International journal of dermatology 20030901

Title: Ciclopirox for the treatment of superficial fungal infections: a review.

Journal: International journal of dermatology 20030901

Title: Evaluation of in vitro activity of ciclopirox olamine, butenafine HCl and econazole nitrate against dermatophytes, yeasts and bacteria.

Journal: International journal of dermatology 20030901

Title: Ciclopirox gel for seborrheic dermatitis of the scalp.

Journal: International journal of dermatology 20030901

Title: Interdigital tinea pedis (dermatophytosis simplex and complex) and treatment with ciclopirox 0.77% gel.

Journal: International journal of dermatology 20030901

Title: Ciclopirox gel in the treatment of patients with interdigital tinea pedis.

Journal: International journal of dermatology 20030901

Title: In vitro susceptibility testing of ciclopirox, terbinafine, ketoconazole and itraconazole against dermatophytes and nondermatophytes, and in vitro evaluation of combination antifungal activity.

Journal: The British journal of dermatology 20030801

Title: The use of topical therapies to treat onychomycosis.

Journal: Dermatologic clinics 20030701

Title: Ciclopirox olamine treatment affects the expression pattern of Candida albicans genes encoding virulence factors, iron metabolism proteins, and drug resistance factors.

Journal: Antimicrobial agents and chemotherapy 20030601

Title: Anodic polarographic determination of ciclopirox olamine in pure and certain pharmaceutical preparations.

Journal: Journal of pharmaceutical and biomedical analysis 20030601

Title: The antimycotic ciclopirox olamine induces HIF-1alpha stability, VEGF expression, and angiogenesis.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030401

Title: Onychomycosis: current treatment options.

Journal: Journal of the American Academy of Nurse Practitioners 20030401

Title: Economic analysis of oral and topical therapies for onychomycosis of the toenails and fingernails.

Journal: Managed care (Langhorne, Pa.) 20030301

Title: The possible mechanism of action of ciclopirox olamine in the yeast Saccharomyces cerevisiae.

Journal: Molecules and cells 20030227

Title: Topical treatments for onychomycosis: a historical perspective.

Journal: Journal of the American Podiatric Medical Association 20030101

Title: Seborrheic dermatitis today, gone tomorrow? The link between the biocene and treatment.

Journal: Dermatology (Basel, Switzerland) 20030101

Title: Randomized, open-labeled, non-inferiority study between ciclopiroxolamine 1% cream and ketoconazole 2% foaming gel in mild to moderate facial seborrheic dermatitis.

Journal: Dermatology (Basel, Switzerland) 20030101

Title: Ciclopirox olamine: head to foot.

Journal: Journal of drugs in dermatology : JDD 20030101

Title: Ciclopiroxolamine cream for treating seborrheic dermatitis: a double-blind parallel group comparison.

Journal: Infection 20021201

Title: Ciclopiroxolamine: in vitro antifungal activity against clinical yeast isolates.

Journal: International journal of antimicrobial agents 20021101

Title: Randomized prospective comparative study: short-term treatment with ciclopiroxolamine (cream and solution) versus boric acid in the treatment of otomycosis.

Journal: Mycoses 20021001

Title: Ciclopirox prevents peroxynitrite toxicity in astrocytes by maintaining their mitochondrial function: a novel mechanism for cytoprotection by ciclopirox.

Journal: Neuropharmacology 20020901

Title: The antifungal drug ciclopirox inhibits deoxyhypusine and proline hydroxylation, endothelial cell growth and angiogenesis in vitro.

Journal: International journal of cancer 20020801

Title: [Batrafen in the treatment of fungal diseases of the skin and nails].

Journal: Voenno-meditsinskii zhurnal 20020801

Title: [Tinea].

Journal: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20020701

Title: A randomised, single-blind, single-centre clinical trial to evaluate comparative clinical efficacy of shampoos containing ciclopirox olamine (1.5%) and salicylic acid (3%), or ketoconazole (2%, Nizoral) for the treatment of dandruff/seborrhoeic dermatitis.

Journal: The Journal of dermatological treatment 20020601

Title: Treatment of dermatophyte toenail onychomycosis in the United States. A pharmacoeconomic analysis.

Journal: Journal of the American Podiatric Medical Association 20020501

Title: Homologous recombination induced by replication inhibition, is stimulated by expression of mutant p53.

Journal: Oncogene 20020117

Title: [Mode of action of ciclopiroxolamine on Candida albicans].

Journal: Mycoses 20020101

Title: A method to measure the amount of drug penetrated across the nail plate.

Journal: Pharmaceutical research 20011001

Title: Ciclopirox nail lacquer: a brush with onychomycosis.

Journal: Cutis 20010801

Title: A multicenter, open-label study of the efficacy and safety of ciclopirox nail lacquer solution 8% for the treatment of onychomycosis in patients with diabetes.

Journal: Cutis 20010801

Title: Successful treatment of onychomycosis with ciclopirox nail lacquer: a case report.

Journal: Cutis 20010801

Title: [Treatment of therapy refractory verrucae vulgares with a ciclopirox-containing lacquer].

Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20010601

Title: Allergic contact dermatitis from ciclopirox olamine.

Journal: The Australasian journal of dermatology 20010501

Title: Randomized, placebo-controlled, double-blind study on clinical efficacy of ciclopiroxolamine 1% cream in facial seborrhoeic dermatitis.

Journal: The British journal of dermatology 20010501

Title: Ciclopirox: an overview.

Journal: International journal of dermatology 20010501

Title: [The in vitro properties of a new hydroxypyridone antimycotic rilopirox, with special reference to its anti-Candida activity].

Journal: The Japanese journal of antibiotics 19990201

Title: The hydroxypyridones: a class of antimycotics of its own.

Journal: Mycoses 19971101

Title: Niewerth M, et al. Ciclopirox olamine treatment affects the expression pattern of Candida albicans genes encoding virulence factors, iron metabolism proteins, and drug resistance factors. Antimicrob Agents Chemother. 2003 Jun;47(6):1805-17.

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Tags:41621-49-2 Molecular Formula|41621-49-2 MDL|41621-49-2 SMILES|41621-49-2 2-aminoethan-1-ol; 6-cyclohexyl-1-hydroxy-4-methyl-1,2-dihydropyridin-2-one