Home Amines 68890-66-4
68890-66-4,MFCD01690792
Catalog No.:AA00IBSW

68890-66-4 | Piroctone olamine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
50mg
97%
in stock  
$7.00   $5.00
- +
100mg
97%
in stock  
$11.00   $8.00
- +
1g
97%
in stock  
$37.00   $26.00
- +
5g
97%
in stock  
$79.00   $55.00
- +
10g
97%
in stock  
$112.00   $78.00
- +
25g
97%
in stock  
$195.00   $137.00
- +
100g
97%
in stock  
$444.00   $311.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00IBSW
Chemical Name:
Piroctone olamine
CAS Number:
68890-66-4
Molecular Formula:
C16H30N2O3
Molecular Weight:
298.4210
MDL Number:
MFCD01690792
SMILES:
CC(CC(C)(C)C)Cc1cc(C)cc(=O)n1O.NCCO
Properties
Computed Properties
 
Complexity:
371  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
5  
Undefined Atom Stereocenter Count:
1  

Downstream Synthesis Route
6A-O-methacryloyl-β-cyclodextrin 
  68890-66-4   
C2H7NO*C14H23NO2*C46H74O36 

[1]Dollendorf;Maier;Janda;Ritter[JournalofInclusionPhenomenaandMacrocyclicChemistry,2013,vol.77,#1-4,p.351-361]

68890-66-4    7585-39-9   
C42H70O35*C2H7NO*C14H23NO2 

[1]Dollendorf;Maier;Janda;Ritter[JournalofInclusionPhenomenaandMacrocyclicChemistry,2013,vol.77,#1-4,p.351-361]

68890-66-4   
4-methyl-6-(2,4,4-trimethylpentyl)pyridine-2(1H)-thione 

[1]CurrentPatentAssignee:NEUROTHERYXCANADA-US2017/327463,2017,A1Locationinpatent:Paragraph0584;0585

68890-66-4   
6-(2,4,4-trimethylpentyl)-1-hydroxy-4-methyl-2(1H)-pyridone 

[1]CurrentPatentAssignee:CLARIANTAG-WO2019/228988,2019,A1Locationinpatent:Page/Pagecolumn88;89

Literature

Title: Efficacy of a piroctone olamine/climbazol shampoo in comparison with a zinc pyrithione shampoo in subjects with moderate to severe dandruff.

Journal: International journal of cosmetic science 20110601

Title: Increased in vivo efficacy of lenalidomide by addition of piroctone olamine.

Journal: In vivo (Athens, Greece) 20110101

Title: Allergic contact dermatitis to propyl gallate and pentylene glycol in an emollient cream.

Journal: The Australasian journal of dermatology 20100501

Title: The in vitro effect of a collagenolytic enzyme inhibitor on lesion development in root dentin.

Journal: American journal of dentistry 20090401

Title: Treatment of mild to moderate seborrhoeic dermatitis with MAS064D (Sebclair), a novel topical medical device: results of a pilot, randomized, double-blind, controlled trial.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20080301

Title: In vitro investigations on the mode of action of the hydroxypyridone antimycotics rilopirox and piroctone on Candida albicans.

Journal: Mycoses 20060501

Title: [Determination of antidangdruff agent salicylic acid, zinc pyrithione, octopirox, climbazole and ketoconazole in shampoo by high performance liquid chromatography].

Journal: Wei sheng yan jiu = Journal of hygiene research 20050901

Title: In vitro antimycotic activity and nail permeation models of a piroctone olamine (octopirox) containing transungual water soluble technology.

Journal: Arzneimittel-Forschung 20050101

Title: Enhanced delivery of an anti-dandruff active in a shampoo vehicle.

Journal: Journal of cosmetic science 20040101

Title: Hybrid-versus-parental strain reaction. I. Comparative mortality in allogenetic and parental strain male and female mice.

Journal: Journal of the National Cancer Institute 19751101

Title: Youn HJ, et al. Efficacy and Safety of Cream Containing Climbazole/Piroctone Olamine for Facial Seborrheic Dermatitis: A Single-Center, Open-Label Split-Face Clinical Study. Ann Dermatol. 2016 Dec;28(6):733-739.

Title: do Couto FM, et al. Antifungal activity of the piroctone olamine in experimental intra-abdominal candidiasis. Springerplus. 2016 Apr 16;5:468.

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