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427878-41-9,MFCD08448162
Catalog No.:AA00BZOQ

427878-41-9 | Ethyl 4-chloro-5-methylpyrrolo[1,2-f][1,2,4]triazine-6-carboxylate

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100mg
95%
in stock  
$153.00   $107.00
- +
250mg
95%
in stock  
$255.00   $179.00
- +
500mg
95%
in stock  
$366.00   $256.00
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1g
95%
in stock  
$546.00   $383.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00BZOQ
Chemical Name:
Ethyl 4-chloro-5-methylpyrrolo[1,2-f][1,2,4]triazine-6-carboxylate
CAS Number:
427878-41-9
Molecular Formula:
C10H10ClN3O2
Molecular Weight:
239.6583
MDL Number:
MFCD08448162
SMILES:
Cc1c(cn2c1c(Cl)ncn2)C(=O)OCC
Properties
Properties
 
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
277  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
3  
XLogP3:
2  

Downstream Synthesis Route
427878-41-9    288385-88-6   
4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo2,1-f1,2,4triazine-6-carboxylicacidethylester 

[1]JournalofMedicinalChemistry,2008,vol.51,p.1976-1980

[2]Patent:WO2004/9542,2004,A2.Locationinpatent:Page31

[3]OrganicProcessResearchandDevelopment,2014,vol.18,p.89-102

[1]HynesJr.,John;Dyckman,AlaricJ.;Lin,Shuqun;Wrobleski,StephenT.;Wu,Hong;Gillooly,KathleenM.;Kanner,StevenB.;Lonial,Herinder;Loo,Derek;McIntyre,KimW.;Pitt,Sidney;Ding,RenShen;Shuster,DavidJ.;Yang,XiaoXia;Zhang,Rosemary;Behnia,Kamelia;Zhang,Hongjian;Marathe,PunitH.;Doweyko,ArthurM.;Tokarski,JohnS.;Sack,JohnS.;Pokross,Matthew;Kiefer,SusanE.;Newitt,JohnA.;Barrish,JoelC.;Dodd,John;Schieven,GaryL.;Leftheris,Katerina[JournalofMedicinalChemistry,2008,vol.51,#1,p.4-16]

[2]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO-WO2003/90912,2003,A1Locationinpatent:Page/Pagecolumn111-112

[1]Wrobleski,StephenT.;Lin,Shuqun;HynesJr.,John;Wu,Hong;Pitt,Sidney;Shen,DingRen;Zhang,Rosemary;Gillooly,KathleenM.;Shuster,DavidJ.;McIntyre,KimW.;Doweyko,ArthurM.;Kish,KevinF.;Tredup,JeffreyA.;Duke,GeraldJ.;Sack,JohnS.;McKinnon,Murray;Dodd,John;Barrish,JoelC.;Schieven,GaryL.;Leftheris,Katerina[BioorganicandMedicinalChemistryLetters,2008,vol.18,#8,p.2739-2744]

[1]Wrobleski,StephenT.;Lin,Shuqun;HynesJr.,John;Wu,Hong;Pitt,Sidney;Shen,DingRen;Zhang,Rosemary;Gillooly,KathleenM.;Shuster,DavidJ.;McIntyre,KimW.;Doweyko,ArthurM.;Kish,KevinF.;Tredup,JeffreyA.;Duke,GeraldJ.;Sack,JohnS.;McKinnon,Murray;Dodd,John;Barrish,JoelC.;Schieven,GaryL.;Leftheris,Katerina[BioorganicandMedicinalChemistryLetters,2008,vol.18,#8,p.2739-2744]

[1]Locationinpatent:experimentalpartLiu,Chunjian;Lin,James;Wrobleski,StephenT.;Lin,Shuqun;Hynes,John;Wu,Hong;Dyckman,AlaricJ.;Li,Tianle;Wityak,John;Gillooly,KathleenM.;Pitt,Sidney;Shen,DingRen;Zhang,RosemaryF.;McIntyre,KimW.;Salter-Cid,Luisa;Shuster,DavidJ.;Zhang,Hongjian;Marathe,PunitH.;Doweyko,ArthurM.;Sack,JohnS.;Kiefer,SusanE.;Kish,KevinF.;Newitt,JohnA.;McKinnon,Murray;Dodd,JohnH.;Barrish,JoelC.;Schieven,GaryL.;Leftheris,Katerina[JournalofMedicinalChemistry,2010,vol.53,#18,p.6629-6639]

Literature
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Tags:427878-41-9 Molecular Formula|427878-41-9 MDL|427878-41-9 SMILES|427878-41-9 Ethyl 4-chloro-5-methylpyrrolo[1,2-f][1,2,4]triazine-6-carboxylate