Home Nitro Compounds 433695-36-4
433695-36-4,MFCD03039912
Catalog No.:AA00D9NY

433695-36-4 | 5-Nitro-2,N,N-trimethylbenzenesulfonamide

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
98%
in stock  
$17.00   $12.00
- +
10mg
98%
in stock  
$25.00   $18.00
- +
25mg
98%
in stock  
$42.00   $29.00
- +
50mg
98%
in stock  
$71.00   $50.00
- +
250mg
98%
in stock  
$95.00   $67.00
- +
1g
>98.0%(HPLC)(N)
in stock  
$149.00   $104.00
- +
5g
98%
in stock  
$610.00   $427.00
- +
10g
98%
in stock  
$1,009.00   $706.00
- +
25g
98%
in stock  
$2,007.00   $1,405.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00D9NY
Chemical Name:
5-Nitro-2,N,N-trimethylbenzenesulfonamide
CAS Number:
433695-36-4
Molecular Formula:
C9H12N2O4S
Molecular Weight:
244.2676
MDL Number:
MFCD03039912
SMILES:
Cc1ccc(cc1S(=O)(=O)N(C)C)[N+](=O)[O-]
Properties
Properties
 
Form:
Solid  
MP:
65-67°C  
Solubility:
DMSO: 12 mg/mL  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
355  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
5  
Rotatable Bond Count:
2  
XLogP3:
1.3  

Literature

Title: New classes of PDE7 inhibitors identified by a fission yeast-based HTS.

Journal: Journal of biomolecular screening 20100401

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: Discovery and structure-activity study of a novel benzoxaborole anti-inflammatory agent (AN2728) for the potential topical treatment of psoriasis and atopic dermatitis.

Journal: Bioorganic & medicinal chemistry letters 20090415

Title: Discovery of BRL 50481 [3-(N,N-dimethylsulfonamido)-4-methyl-nitrobenzene], a selective inhibitor of phosphodiesterase 7: in vitro studies in human monocytes, lung macrophages, and CD8+ T-lymphocytes.

Journal: Molecular pharmacology 20041201

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Safavi M, et al. New methods for the discovery and synthesis of PDE7 inhibitors as new drugs for neurologicaland inflammatory disorders. Expert Opin Drug Discov. 2013 Jun;8(6):733-51.

Title: Smith SJ, et al. Discovery of BRL 50481 -(N,N-dimethylsulfonamido)-4-methyl-nitrobenzene, a selective inhibitor of phosphodiesterase 7: in vitro studies in human monocytes, lung macrophages, and CD8+ T-lymphocytes. Mol Pharmacol. 2004 Dec;66(6):1679-89.

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SDS
Tags:433695-36-4 Molecular Formula|433695-36-4 MDL|433695-36-4 SMILES|433695-36-4 5-Nitro-2,N,N-trimethylbenzenesulfonamide