Home Aldehydes 4425-59-6
4425-59-6,MFCD18377703
Catalog No.:AA00DZKU

4425-59-6 | 6-Amino-2-oxo-1,2-dihydropyrimidine-5-carbaldehyde

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
3 weeks  
$366.00   $256.00
- +
5mg
3 weeks  
$456.00   $319.00
- +
10mg
3 weeks  
$695.00   $486.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00DZKU
Chemical Name:
6-Amino-2-oxo-1,2-dihydropyrimidine-5-carbaldehyde
CAS Number:
4425-59-6
Molecular Formula:
C5H5N3O2
Molecular Weight:
139.1121
MDL Number:
MFCD18377703
SMILES:
O=Cc1cnc(=O)[nH]c1N
Properties
Computed Properties
 
Complexity:
241  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
-1  

Literature

Title: Sequencing the sixth base (5-hydroxymethylcytosine): selective DNA oxidation enables base-pair resolution.

Journal: Angewandte Chemie (International ed. in English) 20121022

Title: 5-formylcytosine and 5-carboxylcytosine reduce the rate and substrate specificity of RNA polymerase II transcription.

Journal: Nature structural & molecular biology 20120801

Title: Crystal structure of human methyl-binding domain IV glycosylase bound to abasic DNA.

Journal: Journal of molecular biology 20120713

Title: [Oxidation and deamination of nucleobases as an epigenetic tool].

Journal: Postepy higieny i medycyny doswiadczalnej (Online) 20120524

Title: Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution.

Journal: Science (New York, N.Y.) 20120518

Title: Epiblast stem cell-based system reveals reprogramming synergy of germline factors.

Journal: Cell stem cell 20120406

Title: DNA glycosylases: in DNA repair and beyond.

Journal: Chromosoma 20120201

Title: Tet2 disruption leads to enhanced self-renewal and altered differentiation of fetal liver hematopoietic stem cells.

Journal: Scientific reports 20120101

Title: The genetic and epigenetic journey of embryonic stem cells into mature neural cells.

Journal: Frontiers in genetics 20120101

Title: 5-Methylcytosine and 5-hydroxymethylcytosine spatiotemporal profiles in the mouse zygote.

Journal: PloS one 20120101

Title: Dissecting epigenetic silencing complexity in the mouse lung cancer suppressor gene Cadm1.

Journal: PloS one 20120101

Title: Enzymatic analysis of Tet proteins: key enzymes in the metabolism of DNA methylation.

Journal: Methods in enzymology 20120101

Title: Active DNA demethylation by oxidation and repair.

Journal: Cell research 20111201

Title: Generation and replication-dependent dilution of 5fC and 5caC during mouse preimplantation development.

Journal: Cell research 20111201

Title: Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation.

Journal: Genes & development 20111201

Title: Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites.

Journal: The Journal of biological chemistry 20111014

Title: Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine.

Journal: Science (New York, N.Y.) 20110902

Title: Molecular biology. Demystifying DNA demethylation.

Journal: Science (New York, N.Y.) 20110902

Title: The discovery of 5-formylcytosine in embryonic stem cell DNA.

Journal: Angewandte Chemie (International ed. in English) 20110725

Title: Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates.

Journal: PloS one 20100101

Title: The pH effect on the naphthoquinone-photosensitized oxidation of 5-methylcytosine.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

Title: Cleavage at 5-methylcytosine in DNA by photosensitized oxidation with 2-methyl-1,4-naphthoquinone tethered oligodeoxynucleotides.

Journal: Bioorganic & medicinal chemistry letters 20050201

Title: Mammalian 5-formyluracil-DNA glycosylase. 2. Role of SMUG1 uracil-DNA glycosylase in repair of 5-formyluracil and other oxidized and deaminated base lesions.

Journal: Biochemistry 20030506

Title: Mutagenicity of 5-formylcytosine, an oxidation product of 5-methylcytosine, in DNA in mammalian cells.

Journal: Journal of biochemistry 20021001

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:4425-59-6 Molecular Formula|4425-59-6 MDL|4425-59-6 SMILES|4425-59-6 6-Amino-2-oxo-1,2-dihydropyrimidine-5-carbaldehyde