+1 858-523-8231
Login | Register
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
Home Other Building Blocks 443913-15-3
443913-15-3,MFCD30533549
Catalog No.:AA01EOGI

443913-15-3 | p38-α MAPK-IN-1

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
1 week  
$170.00   $119.00
- +
5mg
95%
1 week  
$349.00   $244.00
- +
10mg
95%
1 week  
$530.00   $371.00
- +
25mg
95%
1 week  
$848.00   $594.00
- +
50mg
95%
1 week  
$1,183.00   $828.00
- +
100mg
95%
1 week  
$1,578.00   $1,104.00
- +
500mg
95%
1 week  
$3,098.00   $2,168.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01EOGI
Chemical Name:
p38-α MAPK-IN-1
CAS Number:
443913-15-3
Molecular Formula:
C27H35N5O3
Molecular Weight:
477.5985
MDL Number:
MFCD30533549
SMILES:
O=C(Nc1cc(nn1c1ccc(cc1)C)C(C)(C)C)Nc1ccc(cc1)OCCN1CCOCC1
Properties
Computed Properties
 
Complexity:
650  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
35  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
8  
XLogP3:
4.5  

Literature

Title: Displacement assay for the detection of stabilizers of inactive kinase conformations.

Journal: Journal of medicinal chemistry 20100114

Title: The kinetics of binding to p38MAP kinase by analogues of BIRB 796.

Journal: Bioorganic & medicinal chemistry letters 20030915

Title: Pyrazole urea-based inhibitors of p38 MAP kinase: from lead compound to clinical candidate.

Journal: Journal of medicinal chemistry 20020704

Title: Kluter S, et al. Displacement assay for the detection of stabilizers of inactive kinase conformations. J Med Chem. 2010 Jan 14;53(1):357-67.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 443913-15-3
285983-48-4

285983-48-4
Building Blocks
More >
Tags:443913-15-3 Molecular Formula|443913-15-3 MDL|443913-15-3 SMILES|443913-15-3 p38-α MAPK-IN-1