Title: Polydatin ameliorates renal ischemia/reperfusion injury by decreasing apoptosis and oxidative stress through activating sonic hedgehog signaling pathway.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20161001
Title: Mono-2-ethyhexyl phthalate advancing the progression of prostate cancer through activating the hedgehog pathway in LNCaP cells.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20160401
Title: MAPK and SHH pathways modulate type 3 deiodinase expression in papillary thyroid carcinoma.
Journal: Endocrine-related cancer 20160301
Title: White-to-brown metabolic conversion of human adipocytes by JAK inhibition.
Journal: Nature cell biology 20150101
Title: Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition.
Journal: Nature medicine 20140701
Title: Primary cilia mediate sonic hedgehog signaling to regulate neuronal-like differentiation of bone mesenchymal stem cells for resveratrol induction in vitro.
Journal: Journal of neuroscience research 20140501
Title: Protein and mRNA expression of Shh, Smo and Gli1 and inhibition by cyclopamine in hepatocytes of rats with chronic fluorosis.
Journal: Toxicology letters 20140303
Title: Quantitative high-throughput profiling of environmental chemicals and drugs that modulate farnesoid X receptor.
Journal: Scientific reports 20140101
Title: NODAL and SHH dose-dependent double inhibition promotes an HPE-like phenotype in chick embryos.
Journal: Disease models & mechanisms 20130301
Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Journal: Bioorganic & medicinal chemistry 20121115
Title: Identification of a novel Smoothened antagonist that potently suppresses Hedgehog signaling.
Journal: Bioorganic & medicinal chemistry 20121115
Title: Inhibition of hedgehog signaling depresses self-renewal of pancreatic cancer stem cells and reverses chemoresistance.
Journal: International journal of oncology 20121101
Title: Response to inhibition of smoothened in diverse epithelial cancer cells that lack smoothened or patched 1 mutations.
Journal: International journal of oncology 20121101
Title: Hedgehog partial agonism drives Warburg-like metabolism in muscle and brown fat.
Journal: Cell 20121012
Title: A convenient and efficient one-pot conversion of peimisine into cyclopamine.
Journal: Fitoterapia 20121001
Title: Antagonistic cross-regulation between Wnt and Hedgehog signalling pathways controls post-embryonic retinal proliferation.
Journal: Development (Cambridge, England) 20121001
Title: Evaluation of the Metabolic Response to Cyclopamine Therapy in Pancreatic Cancer Xenografts Using a Clinical PET-CT System.
Journal: Translational oncology 20121001
Title: SDF-1/CXCR4 signaling induces pancreatic cancer cell invasion and epithelial-mesenchymal transition in vitro through non-canonical activation of Hedgehog pathway.
Journal: Cancer letters 20120928
Title: Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans.
Journal: Hepatology (Baltimore, Md.) 20120901
Title: Hedgehog-GLI signaling drives self-renewal and tumorigenicity of human melanoma-initiating cells.
Journal: Stem cells (Dayton, Ohio) 20120901
Title: Diindolylmethane-mediated Gli1 protein suppression induces anoikis in ovarian cancer cells in vitro and blocks tumor formation ability in vivo.
Journal: The Journal of biological chemistry 20120817
Title: Additive effects of sonic hedgehog and Nell-1 signaling in osteogenic versus adipogenic differentiation of human adipose-derived stromal cells.
Journal: Stem cells and development 20120810
Title: Targeting the sonic hedgehog pathway in keratocystic odontogenic tumor.
Journal: The Journal of biological chemistry 20120803
Title: The insecticide synergist piperonyl butoxide inhibits hedgehog signaling: assessing chemical risks.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120801
Title: Combined effects of EGFR and Hedgehog signaling pathway inhibition on the proliferation and apoptosis of pancreatic cancer cells.
Journal: Oncology reports 20120801
Title: Green tea epigallocatechin-3-gallate (EGCG) promotes neural progenitor cell proliferation and sonic hedgehog pathway activation during adult hippocampal neurogenesis.
Journal: Molecular nutrition & food research 20120801
Title: In vitro and in vivo characterization of a novel Hedgehog signaling antagonist in human glioblastoma cell lines.
Journal: International journal of cancer 20120715
Title: [Effects and mechanisms of combined suppression of epidermal growth factor receptor and hedgehog signaling on proliferation in pancreatic cancer cells].
Journal: Zhonghua yi xue za zhi 20120710
Title: Interactions between bone marrow stromal microenvironment and B-chronic lymphocytic leukemia cells: any role for Notch, Wnt and Hh signaling pathways?
Journal: Cellular signalling 20120701
Title: Activation of Indian hedgehog promotes chondrocyte hypertrophy and upregulation of MMP-13 in human osteoarthritic cartilage.
Journal: Osteoarthritis and cartilage 20120701
Title: Development of a monoclonal antibody-based ELISA for the hedgehog inhibitors cyclopamine and KAAD-cyclopamine.
Journal: Journal of pharmaceutical and biomedical analysis 20120701
Title: Smoothened antagonists reverse taxane resistance in ovarian cancer.
Journal: Molecular cancer therapeutics 20120701
Title: Inhibition of hedgehog signaling induces monocytic differentiation of HL-60 cells.
Journal: Leukemia & lymphoma 20120601
Title: Gli inhibitor GANT61 causes apoptosis in myeloid leukemia cells and acts in synergy with rapamycin.
Journal: Leukemia research 20120601
Title: Folate deprivation enhances invasiveness of human colon cancer cells mediated by activation of sonic hedgehog signaling through promoter hypomethylation and cross action with transcription nuclear factor-kappa B pathway.
Journal: Carcinogenesis 20120601
Title: Hedgehog regulates angiogenesis of intersegmental vessels through the VEGF signaling pathway.
Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20120601
Title: Attenuation of Notch and Hedgehog signaling is required for fate specification in the spinal cord.
Journal: PLoS genetics 20120601
Title: [Indian Hedgehog signaling is involved in the stretch induced proliferation of osteoblast].
Journal: Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 20120601
Title: The protective effect of sonic hedgehog is mediated by the phosphoinositide [corrected] 3-kinase/AKT/Bcl-2 pathway in cultured rat astrocytes under oxidative stress.
Journal: Neuroscience 20120503
Title: Sonic hedgehog is cytoprotective against oxidative challenge in a cellular model of amyotrophic lateral sclerosis.
Journal: Journal of molecular neuroscience : MN 20120501
Title: Pharmacological modulation of the Hedgehog pathway differentially affects dorsal/ventral patterning in mouse and human embryonic stem cell models of telencephalic development.
Journal: Stem cells and development 20120501
Title: Sonic hedgehog maintains survival and growth of chronic myeloid leukemia progenitor cells through β-catenin signaling.
Journal: Experimental hematology 20120501
Title: Sonic hedgehog signaling mediates epithelial-mesenchymal communication and promotes renal fibrosis.
Journal: Journal of the American Society of Nephrology : JASN 20120501
Title: Sonic Hedgehog pathway is essential for neuroblastoma cell proliferation and tumor growth.
Journal: Molecular and cellular biochemistry 20120501
Title: Hedgehog signaling in glioblastoma multiforme.
Journal: Cancer biology & therapy 20120501
Title: Off-target function of the Sonic hedgehog inhibitor cyclopamine in mediating apoptosis via nitric oxide-dependent neutral sphingomyelinase 2/ceramide induction.
Journal: Molecular cancer therapeutics 20120501
Title: A low-grade ovarian carcinoma case with coincident LOH of PTCH1 and BRCA1, and a mutation in BRCA1.
Journal: International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 20120501
Title: Indian hedgehog signaling is required for proper formation, maintenance and migration of Xenopus neural crest.
Journal: Developmental biology 20120415
Title: Cooperation between Shh and IGF-I in promoting myogenic proliferation and differentiation via the MAPK/ERK and PI3K/Akt pathways requires Smo activity.
Journal: Journal of cellular physiology 20120401
Title: Activation of the Sonic Hedgehog pathway in thyroid neoplasms and its potential role in tumor cell proliferation.
Journal: Endocrine-related cancer 20120401
Title: Transcriptional responses of zebrafish embryos exposed to potential sonic hedgehog pathway interfering compounds deviate from expression profiles of cyclopamine.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20120401
Title: Estradiol triggers sonic-hedgehog-induced angiogenesis during peripheral nerve regeneration by downregulating hedgehog-interacting protein.
Journal: Laboratory investigation; a journal of technical methods and pathology 20120401
Title: Hedgehog signaling plays roles in epithelial cell proliferation in neonatal mouse uterus and vagina.
Journal: Cell and tissue research 20120401
Title: Hedgehog-mediated regulation of PPARγ controls metabolic patterns in neural precursors and shh-driven medulloblastoma.
Journal: Acta neuropathologica 20120401
Title: Combination of hedgehog signaling blockage and chemotherapy leads to tumor reduction in pancreatic adenocarcinomas.
Journal: Pancreas 20120301
Title: INS(GFP/w) human embryonic stem cells facilitate isolation of in vitro derived insulin-producing cells.
Journal: Diabetologia 20120301
Title: Seminiferous cord formation is regulated by hedgehog signaling in the marsupial.
Journal: Biology of reproduction 20120301
Title: Effect of the Hedgehog-inhibitor cyclopamine on mice with osteosarcoma pulmonary metastases.
Journal: International journal of molecular medicine 20120301
Title: Advances in Smoothened-targeting therapies for pancreatic cancer: implication for drug discovery from herbal medicines.
Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20120301
Title: Acylthiourea, acylurea, and acylguanidine derivatives with potent hedgehog inhibiting activity.
Journal: Journal of medicinal chemistry 20120223
Title: Hedgehog signaling inhibition blocks growth of resistant tumors through effects on tumor microenvironment.
Journal: Cancer research 20120215
Title: A mouse model of the most aggressive subgroup of human medulloblastoma.
Journal: Cancer cell 20120214
Title: miR-25 targets TNF-related apoptosis inducing ligand (TRAIL) death receptor-4 and promotes apoptosis resistance in cholangiocarcinoma.
Journal: Hepatology (Baltimore, Md.) 20120201
Title: Hedgehog signaling regulates myelination in the peripheral nervous system through primary cilia.
Journal: Differentiation; research in biological diversity 20120201
Title: Selective inhibitory effect of HPMA copolymer-cyclopamine conjugate on prostate cancer stem cells.
Journal: Biomaterials 20120201
Title: Evaluation of vitamin D3 A-ring analogues as Hedgehog pathway inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20120201
Title: Gene regulatory logic for reading the Sonic Hedgehog signaling gradient in the vertebrate neural tube.
Journal: Cell 20120120
Title: Hedgehog signaling is required for differentiation of endocardial progenitors in zebrafish.
Journal: Developmental biology 20120115
Title: Inhibition of sonic hedgehog signaling aggravates brain damage associated with the down-regulation of Gli1, Ptch1 and SOD1 expression in acute ischemic stroke.
Journal: Neuroscience letters 20120106
Title: The sonic hedgehog pathway as a treatment target for extrahepatic biliary tract cancer.
Journal: Molecular medicine reports 20120101
Title: Yeast-based assay identifies novel Shh/Gli target genes in vertebrate development.
Journal: BMC genomics 20120101
Title: HSPG-deficient zebrafish uncovers dental aspect of multiple osteochondromas.
Journal: PloS one 20120101
Title: Interaction between hedgehog signalling and PAX6 dosage mediates maintenance and regeneration of the corneal epithelium.
Journal: Molecular vision 20120101
Title: Mammalian sex determination—insights from humans and mice.
Journal: Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 20120101
Title: The hedgehog pathway conditions the bone microenvironment for osteolytic metastasis of breast cancer.
Journal: International journal of breast cancer 20120101
Title: Multi-parametric profiling network based on gene expression and phenotype data: a novel approach to developmental neurotoxicity testing.
Journal: International journal of molecular sciences 20120101
Title: Ccdc80-l1 Is involved in axon pathfinding of zebrafish motoneurons.
Journal: PloS one 20120101
Title: Pathobiological implications of the expression of EGFR, pAkt, NF-κB and MIC-1 in prostate cancer stem cells and their progenies.
Journal: PloS one 20120101
Title: Aberrations and therapeutics involving the developmental pathway Hedgehog in pancreatic cancer.
Journal: Vitamins and hormones 20120101
Title: Hedgehog inhibition as an anti-cancer strategy.
Journal: Vitamins and hormones 20120101
Title: The side population in human lung cancer cell line NCI-H460 is enriched in stem-like cancer cells.
Journal: PloS one 20120101
Title: Tissue plasminogen activator and plasminogen activator inhibitor 1 contribute to sonic hedgehog-induced in vitro cerebral angiogenesis.
Journal: PloS one 20120101
Title: Hedgehog signaling in tumor cells facilitates osteoblast-enhanced osteolytic metastases.
Journal: PloS one 20120101
Title: Endothelial cell co-culture mediates maturation of human embryonic stem cell to pancreatic insulin producing cells in a directed differentiation approach.
Journal: Journal of visualized experiments : JoVE 20120101
Title: Hedgehog pathway as a drug target: Smoothened inhibitors in development.
Journal: OncoTargets and therapy 20120101
Title: The expression of irx7 in the inner nuclear layer of zebrafish retina is essential for a proper retinal development and lamination.
Journal: PloS one 20120101
Title: Calcitriol inhibits hedgehog signaling and induces vitamin d receptor signaling and differentiation in the patched mouse model of embryonal rhabdomyosarcoma.
Journal: Sarcoma 20120101
Title: Notch, wnt, and hedgehog pathways in rhabdomyosarcoma: from single pathways to an integrated network.
Journal: Sarcoma 20120101
Title: Shh signaling from the nucleus pulposus is required for the postnatal growth and differentiation of the mouse intervertebral disc.
Journal: PloS one 20120101
Title: Embryonic signaling pathways and rhabdomyosarcoma: contributions to cancer development and opportunities for therapeutic targeting.
Journal: Sarcoma 20120101
Title: A scalable system for production of functional pancreatic progenitors from human embryonic stem cells.
Journal: PloS one 20120101
Title: Dehydroepiandrosterone biosynthesis, role, and mechanism of action in the developing neural tube.
Journal: Frontiers in endocrinology 20120101
Title: Acute myeloid leukemia: focus on novel therapeutic strategies.
Journal: Clinical Medicine Insights. Oncology 20120101
Title: Current knowledge on pancreatic cancer.
Journal: Frontiers in oncology 20120101
Title: Chemoresistance in prostate cancer cells is regulated by miRNAs and Hedgehog pathway.
Journal: PloS one 20120101
Title: Detection of canonical hedgehog signaling in breast cancer by 131-iodine-labeled derivatives of the sonic hedgehog protein.
Journal: Journal of biomedicine & biotechnology 20120101
Title: Hedgehog pathway signaling regulates human colon carcinoma HT-29 epithelial cell line apoptosis and cytokine secretion.
Journal: PloS one 20120101
Title: The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence.
Journal: Science (New York, N.Y.) 20111223
Title: A new cyclopamine glucuronide prodrug with improved kinetics of drug release.
Journal: Organic & biomolecular chemistry 20111221
Title: ABCG2 is a direct transcriptional target of hedgehog signaling and involved in stroma-induced drug tolerance in diffuse large B-cell lymphoma.
Journal: Oncogene 20111208
Title: Active sonic hedgehog signaling between androgen independent human prostate cancer cells and normal/benign but not cancer-associated prostate stromal cells.
Journal: The Prostate 20111201
Title: Semi-quantitative evaluation of CD44(+) /CD24(-) tumor cell distribution in breast cancer tissue using a newly developed fluorescence immunohistochemical staining method.
Journal: Cancer science 20111201
Title: Myofibroblast-derived PDGF-BB promotes Hedgehog survival signaling in cholangiocarcinoma cells.
Journal: Hepatology (Baltimore, Md.) 20111201
Title: Roles of Hedgehog pathway components and retinoic acid signalling in specifying zebrafish ventral spinal cord neurons.
Journal: Development (Cambridge, England) 20111201
Title: Inhibition of the sonic hedgehog pathway by cyplopamine reduces the CD133+/CD15+ cell compartment and the in vitro tumorigenic capability of neuroblastoma cells.
Journal: Cancer letters 20111128
Title: Purmorphamine increases DARPP-32 differentiation in human striatal neural stem cells through the Hedgehog pathway.
Journal: Stem cells and development 20111101
Title: Up-regulation of Hedgehog pathway is associated with cellular permissiveness for hepatitis C virus replication.
Journal: Hepatology (Baltimore, Md.) 20111101
Title: Multipotent mesenchymal stromal cells increase tPA expression and concomitantly decrease PAI-1 expression in astrocytes through the sonic hedgehog signaling pathway after stroke (in vitro study).
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20111101
Title: Antitumoral effects of calcitriol in basal cell carcinomas involve inhibition of hedgehog signaling and induction of vitamin D receptor signaling and differentiation.
Journal: Molecular cancer therapeutics 20111101
Title: Hedgehog signalling promotes germ cell survival in the rat testis.
Journal: Reproduction (Cambridge, England) 20111101
Title: Studies directed toward the elucidation of the pharmacophore of steroid-based Sonic Hedgehog signaling inhibitors.
Journal: Organic letters 20111007
Title: Epithelial mesenchymal transition and hedgehog signaling activation are associated with chemoresistance and invasion of hepatoma subpopulations.
Journal: Journal of hepatology 20111001
Title: Pharmacological inhibition of the Hedgehog pathway prevents human rhabdomyosarcoma cell growth.
Journal: International journal of oncology 20111001
Title: Hedgehog signaling pathway regulates the growth of ovarian cancer spheroid forming cells.
Journal: International journal of oncology 20111001
Title: Hedgehog signaling regulates nociceptive sensitization.
Journal: Current biology : CB 20110927
Title: Stereoselective synthesis of F-ring saturated estrone-derived inhibitors of Hedgehog signaling based on cyclopamine.
Journal: Organic letters 20110916
Title: Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells.
Journal: Cancer research 20110901
Title: ABCG2 is required to control the sonic hedgehog pathway in side population cells with stem-like properties.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20110901
Title: Motoneurons are essential for vascular pathfinding.
Journal: Development (Cambridge, England) 20110901
Title: Vitamin D3 regulates cell viability in gastric cancer and cholangiocarcinoma.
Journal: Anatomy & cell biology 20110901
Title: Ochratoxin A at nanomolar concentration perturbs the homeostasis of neural stem cells in highly differentiated but not in immature three-dimensional brain cell cultures.
Journal: Toxicology letters 20110828
Title: Chemical 'Jekyll and Hyde's: small-molecule inhibitors of developmental signaling pathways.
Journal: Chemical Society reviews 20110814
Title: Protection from lipopolysaccharide-induced pulmonary microvascular endothelial cell injury by activation of hedgehog signaling pathway.
Journal: Molecular biology reports 20110801
Title: Adult-type myogenesis of the frog Xenopus laevis specifically suppressed by notochord cells but promoted by spinal cord cells in vitro.
Journal: In vitro cellular & developmental biology. Animal 20110801
Title: The GLI genes as the molecular switch in disrupting Hedgehog signaling in colon cancer.
Journal: Oncotarget 20110801
Title: Exo-cyclopamine--a stable and potent inhibitor of hedgehog-signaling.
Journal: Chemical communications (Cambridge, England) 20110714
Title: In vitro differentiation of mouse embryonic stem cells into neurons of the dorsal forebrain.
Journal: Cellular and molecular neurobiology 20110701
Title: Increased production of sonic hedgehog by ballooned hepatocytes.
Journal: The Journal of pathology 20110701
Title: Tumor shrinkage by cyclopamine tartrate through inhibiting hedgehog signaling.
Journal: Chinese journal of cancer 20110701
Title: Microvascular retinal endothelial and pericyte cell apoptosis in vitro: role of hedgehog and Notch signaling.
Journal: Investigative ophthalmology & visual science 20110623
Title: Synthesis and biological evaluation of desmethylveramiline, a micromolar Hedgehog inhibitor.
Journal: Bioorganic & medicinal chemistry letters 20110615
Title: Cyclopamine attenuates acute warm ischemia reperfusion injury in cholestatic rat liver: hope for marginal livers.
Journal: Molecular pharmaceutics 20110606
Title: Hedgehog signaling regulates size of the dorsal aortae and density of the plexus during avian vascular development.
Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20110601
Title: Gli1 enhances migration and invasion via up-regulation of MMP-11 and promotes metastasis in ERα negative breast cancer cell lines.
Journal: Clinical & experimental metastasis 20110601
Title: HH/GLI signalling as a new therapeutic target for patients with oral squamous cell carcinoma.
Journal: Oral oncology 20110601
Title: Sonic Hedgehog dependent phosphorylation by CK1α and GRK2 is required for ciliary accumulation and activation of smoothened.
Journal: PLoS biology 20110601
Title: Shh signalling restricts the expression of Gcm2 and controls the position of the developing parathyroids.
Journal: Developmental biology 20110515
Title: Six1 transcription factor is critical for coordination of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung.
Journal: Developmental biology 20110515
Title: Targeting GLI1 expression in human inflammatory breast cancer cells enhances apoptosis and attenuates migration.
Journal: British journal of cancer 20110510
Title: Tandem metathesis reactions of oxabicyclo[2.2.1]heptenes: studies on the spirocyclic core of cyclopamine.
Journal: Organic letters 20110506
Title: Cyclopamine induces eosinophilic differentiation and upregulates CD44 expression in myeloid leukemia cells.
Journal: Leukemia research 20110501
Title: Redundant and differential roles of transcription factors Gli1 and Gli2 in the development of mouse fetal Leydig cells.
Journal: Biology of reproduction 20110501
Title: Vitamin D3 inhibits hedgehog signaling and proliferation in murine Basal cell carcinomas.
Journal: Cancer prevention research (Philadelphia, Pa.) 20110501
Title: Companies race to develop first Hedgehog inhibitor cancer drug.
Journal: Nature medicine 20110501
Title: The promise of human embryonic stem cells in aging-associated diseases.
Journal: Aging 20110501
Title: APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome.
Journal: Human molecular genetics 20110415
Title: Impact of co-culture on pancreatic differentiation of embryonic stem cells.
Journal: Journal of tissue engineering and regenerative medicine 20110401
Title: Hedgehog signaling and therapeutics in pancreatic cancer.
Journal: Carcinogenesis 20110401
Title: Hedgehog signaling induced by breast cancer cells promotes osteoclastogenesis and osteolysis.
Journal: The Journal of biological chemistry 20110318
Title: C. elegans patched-3 is an essential gene implicated in osmoregulation and requiring an intact permease transporter domain.
Journal: Developmental biology 20110315
Title: Coordinated waves of gene expression during neuronal differentiation of embryonic stem cells as basis for novel approaches to developmental neurotoxicity testing.
Journal: Cell death and differentiation 20110301
Title: Identification and mechanism of action of the acylguanidine MRT-83, a novel potent Smoothened antagonist.
Journal: Molecular pharmacology 20110301
Title: Targeting the hedgehog pathway: the development of cyclopamine and the development of anti-cancer drugs targeting the hedgehog pathway.
Journal: Mini reviews in medicinal chemistry 20110301
Title: Hedgehog inhibition with cyclopamine represses tumor growth and prolongs survival in a transgenic mouse model of islet cell tumors.
Journal: Annals of surgery 20110301
Title: Effects of combination of notch inhibitor plus hedgehog inhibitor or Wnt inhibitor on growth of leukemia cells.
Journal: Anticancer research 20110301
Title: Comparative study assessing effects of sonic hedgehog and VEGF in a human co-culture model for bone vascularisation strategies.
Journal: European cells & materials 20110208
Title: Pancreatic cancer spheres are more than just aggregates of stem marker-positive cells.
Journal: Bioscience reports 20110201
Title: In vivo evaluation of mixtures of uncultured freshly isolated adipose-derived stem cells and demineralized bone matrix for bone regeneration in a rat critically sized calvarial defect model.
Journal: Stem cells and development 20110201
Title: Human adipose-derived stromal cells stimulate autogenous skeletal repair via paracrine Hedgehog signaling with calvarial osteoblasts.
Journal: Stem cells and development 20110201
Title: Expression and epigenetic modulation of sonic hedgehog-GLI1 pathway genes in neuroblastoma cell lines and tumors.
Journal: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20110201
Title: Hedgehog signaling drives cellular survival in human colon carcinoma cells.
Journal: Cancer research 20110201
Title: TGF-beta promotion of Gli2-induced expression of parathyroid hormone-related protein, an important osteolytic factor in bone metastasis, is independent of canonical Hedgehog signaling.
Journal: Cancer research 20110201
Title: Sonic hedgehog (Shh)-Gli signaling controls neural progenitor cell division in the developing tectum in zebrafish.
Journal: The European journal of neuroscience 20110201
Title: Historical perspective: beginnings of the beta-cell: current perspectives in beta-cell development.
Journal: Diabetes 20110201
Title: Inhibition of Sonic hedgehog and Notch pathways enhances sensitivity of CD133(+) glioma stem cells to temozolomide therapy.
Journal: Molecular medicine (Cambridge, Mass.) 20110101
Title: Osteopontin is induced by hedgehog pathway activation and promotes fibrosis progression in nonalcoholic steatohepatitis.
Journal: Hepatology (Baltimore, Md.) 20110101
Title: Production of functional glucagon-secreting α-cells from human embryonic stem cells.
Journal: Diabetes 20110101
Title: Targeting the cancer initiating cell: the Achilles' heel of cancer.
Journal: Advances in enzyme regulation 20110101
Title: Hedgehog signalling is required for perichondral osteoblast differentiation in zebrafish.
Journal: Mechanisms of development 20110101
Title: Cancer stem cells: repair gone awry?
Journal: Journal of oncology 20110101
Title: Up-regulation of sonic hedgehog contributes to TGF-β1-induced epithelial to mesenchymal transition in NSCLC cells.
Journal: PloS one 20110101
Title: Basal cell carcinoma: from the molecular understanding of the pathogenesis to targeted therapy of progressive disease.
Journal: Journal of skin cancer 20110101
Title: Inhibition of hedgehog signaling decreases proliferation and clonogenicity of human mesenchymal stem cells.
Journal: PloS one 20110101
Title: Role of cancer stem cells in hepatocarcinogenesis.
Journal: Genome medicine 20110101
Title: Regulation of retinoid receptors by retinoic acid and axonal contact in Schwann cells.
Journal: PloS one 20110101
Title: Sonic hedgehog pathway is essential for maintenance of cancer stem-like cells in human gastric cancer.
Journal: PloS one 20110101
Title: Future perspectives in melanoma research. Meeting report from the 'Melanoma Research: a bridge Naples-USA. Naples, December 6th-7th 2010'.
Journal: Journal of translational medicine 20110101
Title: Hedgehog inhibition promotes a switch from Type II to Type I cell death receptor signaling in cancer cells.
Journal: PloS one 20110101
Title: Rostral growth of commissural axons requires the cell adhesion molecule MDGA2.
Journal: Neural development 20110101
Title: Novel therapeutic strategies for targeting liver cancer stem cells.
Journal: International journal of biological sciences 20110101
Title: Visualization, characterization and modulation of calcium signaling during the development of slow muscle cells in intact zebrafish embryos.
Journal: The International journal of developmental biology 20110101
Title: Ascl1/Mash1 is a novel target of Gli2 during Gli2-induced neurogenesis in P19 EC cells.
Journal: PloS one 20110101
Title: Cyclopamine reverts acquired chemoresistance and down-regulates cancer stem cell markers in pancreatic cancer cell lines.
Journal: Swiss medical weekly 20110101
Title: Breast cancer growth and metastasis: interplay between cancer stem cells, embryonic signaling pathways and epithelial-to-mesenchymal transition.
Journal: Breast cancer research : BCR 20110101
Title: Investigations on inhibitors of hedgehog signal pathway: a quantitative structure-activity relationship study.
Journal: International journal of molecular sciences 20110101
Title: A novel synthetic smoothened antagonist transiently inhibits pancreatic adenocarcinoma xenografts in a mouse model.
Journal: PloS one 20110101
Title: Zebrafish cyclin-dependent protein kinase-like 1 (zcdkl1): identification and functional characterization.
Journal: International journal of molecular sciences 20110101
Title: The regenerative capacity of the zebrafish caudal fin is not affected by repeated amputations.
Journal: PloS one 20110101
Title: Potential applications of curcumin and its novel synthetic analogs and nanotechnology-based formulations in cancer prevention and therapy.
Journal: Chinese medicine 20110101
Title: Zebrafish Ext2 is necessary for Fgf and Wnt signaling, but not for Hh signaling.
Journal: BMC developmental biology 20110101
Title: The hedgehog receptor patched is involved in cholesterol transport.
Journal: PloS one 20110101
Title: Cyclopamine blocked the growth of colorectal cancer SW116 cells by modulating some target genes of Gli1 in vitro.
Journal: Hepato-gastroenterology 20110101
Title: Anti-Aβ drug screening platform using human iPS cell-derived neurons for the treatment of Alzheimer's disease.
Journal: PloS one 20110101
Title: Role of GSK-3β in the osteogenic differentiation of palatal mesenchyme.
Journal: PloS one 20110101
Title: Toll-like receptor 3 regulates neural stem cell proliferation by modulating the Sonic Hedgehog pathway.
Journal: PloS one 20110101
Title: Hedgehog signaling antagonist GDC-0449 (Vismodegib) inhibits pancreatic cancer stem cell characteristics: molecular mechanisms.
Journal: PloS one 20110101
Title: Induced pluripotent stem cells from GMP-grade hematopoietic progenitor cells and mononuclear myeloid cells.
Journal: Stem cell research & therapy 20110101
Title: Expression of DNMT1 and DNMT3a are regulated by GLI1 in human pancreatic cancer.
Journal: PloS one 20110101
Title: Inhibition of Hedgehog signaling antagonizes serous ovarian cancer growth in a primary xenograft model.
Journal: PloS one 20110101
Title: Aberrant Hedgehog ligands induce progressive pancreatic fibrosis by paracrine activation of myofibroblasts and ductular cells in transgenic zebrafish.
Journal: PloS one 20110101
Title: Development of posterior hypothalamic neurons enlightens a switch in the prosencephalic basic plan.
Journal: PloS one 20110101
Title: The use of pluripotent stem cell for personalized cell therapies against neurological disorders.
Journal: Journal of biomedicine & biotechnology 20110101
Title: Tumor Suppressor Function of CYLD in Nonmelanoma Skin Cancer.
Journal: Journal of skin cancer 20110101
Title: Shared signaling pathways in normal and breast cancer stem cells.
Journal: Journal of carcinogenesis 20110101
Title: Therapeutic targeting of cancer stem cells.
Journal: Frontiers in oncology 20110101
Title: The Notch target Hes1 directly modulates Gli1 expression and Hedgehog signaling: a potential mechanism of therapeutic resistance.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20101215
Title: Activation of the sonic hedgehog signaling controls human pulmonary arterial smooth muscle cell proliferation in response to hypoxia.
Journal: Biochimica et biophysica acta 20101201
Title: Hedgehog signaling regulates E-cadherin expression for the maintenance of the actin cytoskeleton and tight junctions.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20101201
Title: A network of Wnt, hedgehog and BMP signaling pathways regulates tooth replacement in snakes.
Journal: Developmental biology 20101201
Title: Agents targeting the Hedgehog pathway for pancreatic cancer treatment.
Journal: Current opinion in investigational drugs (London, England : 2000) 20101201
Title: Hedgehog antagonists cyclopamine and dihydroveratramine can be mistaken for each other in Veratrum album.
Journal: Journal of pharmaceutical and biomedical analysis 20101102
Title: Sonic Hedgehog/GLI₁ signaling pathway inhibition restricts cell migration and invasion in human gliomas.
Journal: Neurological research 20101101
Title: Protective effect of hedgehog signaling on cytokine-induced cytotoxicity in pancreatic beta-cells.
Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20101101
Title: Inhibition of endogenous hedgehog signaling protects against acute liver injury after ischemia reperfusion.
Journal: Pharmaceutical research 20101101
Title: Gli3 mediates cell survival and sensitivity to cyclopamine in pancreatic cancer.
Journal: Cancer biology & therapy 20101101
Title: The inhibitory effect of cyclopamine on human non-small cell lung cancer.
Journal: Saudi medical journal 20101101
Title: Targeting metabolic remodeling in glioblastoma multiforme.
Journal: Oncotarget 20101101
Title: {Alpha}2B-adrenoceptor deficiency leads to postnatal respiratory failure in mice.
Journal: The Journal of biological chemistry 20101029
Title: Sonic Hedgehog improves in vitro development of porcine parthenotes and handmade cloned embryos.
Journal: Theriogenology 20101015
Title: CD133+ cells from medulloblastoma and PNET cell lines are more resistant to cyclopamine inhibition of the sonic hedgehog signaling pathway than CD133- cells.
Journal: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20101001
Title: Erythropoietin and sonic hedgehog mediate the neuroprotective effects of brain-derived neurotrophic factor against mitochondrial inhibition.
Journal: Neurobiology of disease 20101001
Title: Virtual screening-based discovery and mechanistic characterization of the acylthiourea MRT-10 family as smoothened antagonists.
Journal: Molecular pharmacology 20101001
Title: Mouse models and mouse supermodels.
Journal: EMBO molecular medicine 20101001
Title: Blockade of the sonic hedgehog signalling pathway inhibits choroidal neovascularization in a laser-induced rat model.
Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20101001
Title: Modulators of the hedgehog signaling pathway.
Journal: Bioorganic & medicinal chemistry 20100915
Title: Hedgehog antagonist cyclopamine isomerizes to less potent forms when acidified.
Journal: Journal of pharmaceutical and biomedical analysis 20100905
Title: Inactivation of Patched1 in the mouse limb has novel inhibitory effects on the chondrogenic program.
Journal: The Journal of biological chemistry 20100903
Title: Inhibition of GLI, but not Smoothened, induces apoptosis in chronic lymphocytic leukemia cells.
Journal: Oncogene 20100902
Title: Activation of Erk by sonic hedgehog independent of canonical hedgehog signalling.
Journal: The international journal of biochemistry & cell biology 20100901
Title: Sonic hedgehog signaling induces vascular smooth muscle cell proliferation via induction of the G1 cyclin-retinoblastoma axis.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20100901
Title: Recent advances and prospects in the differentiation of pancreatic cells from human embryonic stem cells.
Journal: Diabetes 20100901
Title: Molecular therapy targeting Sonic hedgehog and hepatocyte growth factor signaling in a mouse model of medulloblastoma.
Journal: Molecular cancer therapeutics 20100901
Title: Reduction of human embryonal rhabdomyosarcoma tumor growth by inhibition of the hedgehog signaling pathway.
Journal: Genes & cancer 20100901
Title: Sonic Hedgehog influences the balance of osteogenesis and adipogenesis in mouse adipose-derived stromal cells.
Journal: Tissue engineering. Part A 20100801
Title: Identification of Hedgehog signaling inhibitors with relevant human exposure by small molecule screening.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20100801
Title: Transcriptional suppression of mir-29b-1/mir-29a promoter by c-Myc, hedgehog, and NF-kappaB.
Journal: Journal of cellular biochemistry 20100801
Title: A biomimetic approach to C-nor-D-homo-steroids.
Journal: Journal of the American Chemical Society 20100728
Title: Hedgehog signaling regulates segment formation in the annelid Platynereis.
Journal: Science (New York, N.Y.) 20100716
Title: Gli1 inhibition induces cell-cycle arrest and enhanced apoptosis in brain glioma cell lines.
Journal: Journal of neuro-oncology 20100701
Title: Gli2 expression and human bladder transitional carcinoma cell invasiveness.
Journal: The Journal of urology 20100701
Title: Assessing the efficacy of the hedgehog pathway inhibitor vitamin D3 in a murine xenograft model for pancreatic cancer.
Journal: Cancer biology & therapy 20100701
Title: Expression of sonic hedgehog signaling components in hepatocellular carcinoma and cyclopamine-induced apoptosis through Bcl-2 downregulation in vitro.
Journal: Archives of medical research 20100701
Title: Betulinic acid induces apoptosis and inhibits hedgehog signalling in rhabdomyosarcoma.
Journal: British journal of cancer 20100629
Title: Antitumor and antiplatelet activity of alkaloids from veratrum dahuricum.
Journal: Phytotherapy research : PTR 20100601
Title: Neuroprotective effect of upregulated sonic Hedgehog in retinal ganglion cells following chronic ocular hypertension.
Journal: Investigative ophthalmology & visual science 20100601
Title: Stability study of the human G-protein coupled receptor, Smoothened.
Journal: Biochimica et biophysica acta 20100601
Title: Early development of medaka Oryzias latipes muscles as revealed by transgenic approaches using embryonic and larval types of myosin heavy chain genes.
Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20100601
Title: Dynamic assignment and maintenance of positional identity in the ventral neural tube by the morphogen sonic hedgehog.
Journal: PLoS biology 20100601
Title: Activation of Sonic hedgehog signaling pathway in S-type neuroblastoma cell lines.
Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20100601
Title: Nonsurgical innovations in the treatment of nonmelanoma skin cancer.
Journal: The Journal of clinical and aesthetic dermatology 20100601
Title: Terpenoids and a flavonoid glycoside from Acacia pennata leaves as hedgehog/GLI-mediated transcriptional inhibitors.
Journal: Journal of natural products 20100528
Title: Cyclopamine and hedgehog signaling: chemistry, biology, medical perspectives.
Journal: Angewandte Chemie (International ed. in English) 20100503
Title: Hedgehog signaling in pancreas epithelium regulates embryonic organ formation and adult beta-cell function.
Journal: Diabetes 20100501
Title: Hedgehog signaling is critical for normal liver regeneration after partial hepatectomy in mice.
Journal: Hepatology (Baltimore, Md.) 20100501
Title: [Mechanism of combined use of cyclopamine and hydroxycamptothecin in inducing the apoptosis of human oral squamous cell carcinoma cell line].
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20100501
Title: Common botanical compounds inhibit the hedgehog signaling pathway in prostate cancer.
Journal: Cancer research 20100415
Title: Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth.
Journal: Cancer cell 20100413
Title: Osteogenic oxysterol, 20(S)-hydroxycholesterol, induces notch target gene expression in bone marrow stromal cells.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20100401
Title: Sonic hedgehog promotes angiogenesis and osteogenesis in a coculture system consisting of primary osteoblasts and outgrowth endothelial cells.
Journal: Tissue engineering. Part A 20100401
Title: Novel xenograft and cell line derived from an invasive intraductal papillary mucinous neoplasm of the pancreas give new insights into molecular mechanisms.
Journal: Pancreas 20100401
Title: Study of a cyclopamine glucuronide prodrug for the selective chemotherapy of glioblastoma.
Journal: European journal of medicinal chemistry 20100401
Title: Cleft lip and palate results from Hedgehog signaling antagonism in the mouse: Phenotypic characterization and clinical implications.
Journal: Birth defects research. Part A, Clinical and molecular teratology 20100401
Title: The Hedgehog morphogen in myocardial ischemia-reperfusion injury.
Journal: Experimental biology and medicine (Maywood, N.J.) 20100401
Title: Hedgehog signaling regulates proliferation of prostate cancer cells via stathmin1.
Journal: Clinical and experimental medicine 20100301
Title: Curcumin inhibits the Sonic Hedgehog signaling pathway and triggers apoptosis in medulloblastoma cells.
Journal: Molecular carcinogenesis 20100301
Title: Hedgehog signaling and laminin play unique and synergistic roles in muscle development.
Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20100301
Title: Cytotoxic effects induced by docetaxel, gefitinib, and cyclopamine on side population and nonside population cell fractions from human invasive prostate cancer cells.
Journal: Molecular cancer therapeutics 20100301
Title: Activation of Hedgehog signaling by the environmental toxicant arsenic may contribute to the etiology of arsenic-induced tumors.
Journal: Cancer research 20100301
Title: [Effects of cyclopamine on the proliferation and cycle of prostate cancer cell line DU145].
Journal: Zhonghua nan ke xue = National journal of andrology 20100301
Title: Oestrogen receptor-alpha contributes to the regulation of the hedgehog signalling pathway in ERalpha-positive gastric cancer.
Journal: British journal of cancer 20100216
Title: Mys protein regulates protein kinase A activity by interacting with regulatory type Ialpha subunit during vertebrate development.
Journal: The Journal of biological chemistry 20100212
Title: Corticosteroid-induced kidney dysmorphogenesis is associated with deregulated expression of known cystogenic molecules, as well as Indian hedgehog.
Journal: American journal of physiology. Renal physiology 20100201
Title: Regulation of Sox9 by Sonic Hedgehog (Shh) is essential for patterning and formation of tracheal cartilage.
Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20100201
Title: Controlling destiny through chemistry: small-molecule regulators of cell fate.
Journal: ACS chemical biology 20100115
Title: Late reactivation of sonic hedgehog by Helicobacter pylori results in population of gastric epithelial cells that are resistant to apoptosis: implication for gastric carcinogenesis.
Journal: Cancer letters 20100101
Title: Sonic hedgehog is a potent chemoattractant for human monocytes: diabetes mellitus inhibits Sonic hedgehog-induced monocyte chemotaxis.
Journal: Basic research in cardiology 20100101
Title: Stage-specific role for shh in dopaminergic differentiation of human embryonic stem cells induced by stromal cells.
Journal: Stem cells and development 20100101
Title: Autocrine and paracrine Shh signaling are necessary for tooth morphogenesis, but not tooth replacement in snakes and lizards (Squamata).
Journal: Developmental biology 20100101
Title: Hedgehog pathway activity is required for the lethality and intestinal phenotypes of mice with hyperactive Wnt signaling.
Journal: Mechanisms of development 20100101
Title: Small-molecule modulators of the Sonic Hedgehog signaling pathway.
Journal: Molecular bioSystems 20100101
Title: Sonic Hedgehog gene delivery to the rodent heart promotes angiogenesis via iNOS/netrin-1/PKC pathway.
Journal: PloS one 20100101
Title: Regulation of Emx2 expression by antisense transcripts in murine cortico-cerebral precursors.
Journal: PloS one 20100101
Title: Smoothened as a new therapeutic target for human osteosarcoma.
Journal: Molecular cancer 20100101
Title: A current review of targeted therapeutics for ovarian cancer.
Journal: Journal of oncology 20100101
Title: Hedgehog promotes neovascularization in pancreatic cancers by regulating Ang-1 and IGF-1 expression in bone-marrow derived pro-angiogenic cells.
Journal: PloS one 20100101
Title: BMP-2 functions independently of SHH signaling and triggers cell condensation and apoptosis in regenerating axolotl limbs.
Journal: BMC developmental biology 20100101
Title: Hedgehog/Gli supports androgen signaling in androgen deprived and androgen independent prostate cancer cells.
Journal: Molecular cancer 20100101
Title: A comprehensive panel of three-dimensional models for studies of prostate cancer growth, invasion and drug responses.
Journal: PloS one 20100101
Title: Newly generated cells are increased in hippocampus of adult mice lacking a serine protease inhibitor.
Journal: BMC neuroscience 20100101
Title: T cells enhance stem-like properties and conditional malignancy in gliomas.
Journal: PloS one 20100101
Title: Cancerous stem cells: deviant stem cells with cancer-causing misbehavior.
Journal: Stem cell research & therapy 20100101
Title: A systems approach to mapping transcriptional networks controlling surfactant homeostasis.
Journal: BMC genomics 20100101
Title: The role of tumor initiating cells in drug resistance of breast cancer: Implications for future therapeutic approaches.
Journal: Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20100101
Title: Mtmr8 is essential for vasculature development in zebrafish embryos.
Journal: BMC developmental biology 20100101
Title: Role of Wnt canonical pathway in hematological malignancies.
Journal: Journal of hematology & oncology 20100101
Title: Microparticles carrying Sonic hedgehog favor neovascularization through the activation of nitric oxide pathway in mice.
Journal: PloS one 20100101
Title: cDNA microarray gene expression profiling of hedgehog signaling pathway inhibition in human colon cancer cells.
Journal: PloS one 20100101
Title: Hedgehog signaling is required at multiple stages of zebrafish tooth development.
Journal: BMC developmental biology 20100101
Title: Differentiation of mouse embryonic stem cells into endoderm without embryoid body formation.
Journal: PloS one 20100101
Title: Self-renewal of acute lymphocytic leukemia cells is limited by the Hedgehog pathway inhibitors cyclopamine and IPI-926.
Journal: PloS one 20100101
Title: Visualization of Gli activity in craniofacial tissues of hedgehog-pathway reporter transgenic zebrafish.
Journal: PloS one 20100101
Title: Characterization of new otic enhancers of the pou3f4 gene reveal distinct signaling pathway regulation and spatio-temporal patterns.
Journal: PloS one 20100101
Title: Synthesis of all diastereomers of the piperidine--alkaloid substructure of cyclopamine.
Journal: Organic letters 20091203
Title: Sonic hedgehog is a polarized signal for motor neuron regeneration in adult zebrafish.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20091202
Title: Transgenic zebrafish line with over-expression of Hedgehog on the skin: a useful tool to screen Hedgehog-inhibiting compounds.
Journal: Transgenic research 20091201
Title: Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20091201
Title: Blocking hedgehog signaling after ablation of the dorsal neural tube allows regeneration of the cardiac neural crest and rescue of outflow tract septation.
Journal: Developmental biology 20091115
Title: Sonic hedgehog regulates ischemia/hypoxia-induced neural progenitor proliferation.
Journal: Stroke 20091101
Title: Cyclopamine and quercetin suppress the growth of leukemia and lymphoma cells.
Journal: Anticancer research 20091101
Title: Blockade of hedgehog signaling pathway as a therapeutic strategy for pancreatic cancer.
Journal: Cancer letters 20091008
Title: Hedgehog-mediated epithelial-to-mesenchymal transition and fibrogenic repair in nonalcoholic fatty liver disease.
Journal: Gastroenterology 20091001
Title: Cross talk between hedgehog and bone morphogenetic proteins occurs during cardiomyogenesis in P19 cells.
Journal: In vitro cellular & developmental biology. Animal 20091001
Title: Targeted inhibition of the Hedgehog pathway in established malignant glioma xenografts enhances survival.
Journal: Oncogene 20091001
Title: A critical role of Sonic Hedgehog signaling in maintaining the tumorigenicity of neuroblastoma cells.
Journal: Cancer science 20091001
Title: From teratogens to potential therapeutics: natural inhibitors of the Hedgehog signaling network come of age.
Journal: Planta medica 20091001
Title: Hedgehog signal activation coordinates proliferation and differentiation of fetal liver progenitor cells.
Journal: Experimental cell research 20090910
Title: Review of the hair follicle origin hypothesis for basal cell carcinoma.
Journal: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20090901
Title: Combined targeted treatment to eliminate tumorigenic cancer stem cells in human pancreatic cancer.
Journal: Gastroenterology 20090901
Title: The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation.
Journal: Journal of cell science 20090901
Title: Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion.
Journal: EMBO molecular medicine 20090901
Title: Negative guidance factor-induced macropinocytosis in the growth cone plays a critical role in repulsive axon turning.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090826
Title: The hedgehog pathway transcription factor GLI1 promotes malignant behavior of cancer cells by up-regulating osteopontin.
Journal: The Journal of biological chemistry 20090821
Title: Sonic hedgehog pathway activation is induced by acute brain injury and regulated by injury-related inflammation.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090819
Title: BMP7 and SHH regulate Pax2 in mouse retinal astrocytes by relieving TLX repression.
Journal: Developmental biology 20090815
Title: Recent patents for Hedgehog pathway inhibitors for the treatment of malignancy.
Journal: Expert opinion on therapeutic patents 20090801
Title: Sonic hedgehog improves delayed wound healing via enhancing cutaneous nitric oxide function in diabetes.
Journal: American journal of physiology. Endocrinology and metabolism 20090801
Title: Sonic hedgehog expression and its role in form-deprivation myopia in mice.
Journal: Current eye research 20090801
Title: Discovery of a potent and orally active hedgehog pathway antagonist (IPI-926).
Journal: Journal of medicinal chemistry 20090723
Title: Structure-activity relationships and cancer-cell selective toxicity of novel inhibitors of glioma-associated oncogene homologue 1 (Gli1) mediated transcription.
Journal: Journal of medicinal chemistry 20090723
Title: Sonic hedgehog mediates BDNF-induced neuroprotection against mitochondrial inhibitor 3-nitropropionic acid.
Journal: Biochemical and biophysical research communications 20090717
Title: Development of zebrafish swimbladder: The requirement of Hedgehog signaling in specification and organization of the three tissue layers.
Journal: Developmental biology 20090715
Title: Synthesis and biological evaluation of SANT-2 and analogues as inhibitors of the hedgehog signaling pathway.
Journal: Bioorganic & medicinal chemistry 20090715
Title: Design and synthesis of inhibitors of Hedgehog signaling based on the alkaloid cyclopamine.
Journal: Organic letters 20090702
Title: Cyclopamine-induced synophthalmia in sheep: defining a critical window and toxicokinetic evaluation.
Journal: Journal of applied toxicology : JAT 20090701
Title: Sonic Hedgehog induces Notch target gene expression in vascular smooth muscle cells via VEGF-A.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20090701
Title: Zebrafish ift57, ift88, and ift172 intraflagellar transport mutants disrupt cilia but do not affect hedgehog signaling.
Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20090701
Title: Hedgehog signaling regulates the survival of gastric cancer cells by regulating the expression of Bcl-2.
Journal: International journal of molecular sciences 20090701
Title: Sonic hedgehog maintains proliferation in secondary heart field progenitors and is required for normal arterial pole formation.
Journal: Developmental biology 20090615
Title: Cyclopamine inhibition of human breast cancer cell growth independent of Smoothened (Smo).
Journal: Breast cancer research and treatment 20090601
Title: Deciphering the role of Shh signaling in axial defects produced by ethanol exposure.
Journal: Birth defects research. Part A, Clinical and molecular teratology 20090601
Title: Evidence for allosteric interactions of antagonist binding to the smoothened receptor.
Journal: The Journal of pharmacology and experimental therapeutics 20090601
Title: Bone marrow stromal cells increase oligodendrogenesis after stroke.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20090601
Title: [Hedgehog pathway is associated with the proliferation and differentiation of osteoblasts].
Journal: Shanghai kou qiang yi xue = Shanghai journal of stomatology 20090601
Title: Inhibition of S6K by resveratrol: in search of the purpose.
Journal: Aging 20090601
Title: Signaling hierarchy regulating human endothelial cell development.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20090501
Title: Drug resistance is dramatically restored by hedgehog inhibitors in CD34+ leukemic cells.
Journal: Cancer science 20090501
Title: KAAD-cyclopamine augmented TRAIL-mediated apoptosis in malignant glioma cells by modulating the intrinsic and extrinsic apoptotic pathway.
Journal: Neurobiology of disease 20090501
Title: Germ cell migration in zebrafish is cyclopamine-sensitive but Smoothened-independent.
Journal: Developmental biology 20090415
Title: Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia.
Journal: Nature 20090409
Title: Human fetal radial glia cells generate oligodendrocytes in vitro.
Journal: Glia 20090401
Title: Microparticles harboring Sonic Hedgehog promote angiogenesis through the upregulation of adhesion proteins and proangiogenic factors.
Journal: Carcinogenesis 20090401
Title: Germ cell sex determination in mammals.
Journal: Molecular human reproduction 20090401
Title: Hedgehog signaling is involved in differentiation of normal colonic tissue rather than in tumor proliferation.
Journal: Virchows Archiv : an international journal of pathology 20090401
Title: Lack of evidence for activation of the hedgehog pathway in psoriasis.
Journal: The Journal of investigative dermatology 20090301
Title: Sonic Hedgehog signaling in astrocytes is dependent on p38 mitogen-activated protein kinase and G-protein receptor kinase 2.
Journal: Journal of neurochemistry 20090301
Title: The Hedgehog pathway is a possible therapeutic target for patients with estrogen receptor-negative breast cancer.
Journal: Anticancer research 20090301
Title: Spatial and temporal pattern for the dentition in the Australian lungfish revealed with sonic hedgehog expression profile.
Journal: Proceedings. Biological sciences 20090222
Title: Identification of Hedgehog signaling outcomes in mouse testis development using a hanging drop-culture system.
Journal: Biology of reproduction 20090201
Title: A dynamic Gli code interprets Hh signals to regulate induction, patterning, and endocrine cell specification in the zebrafish pituitary.
Journal: Developmental biology 20090201
Title: A direct pancreatic cancer xenograft model as a platform for cancer stem cell therapeutic development.
Journal: Molecular cancer therapeutics 20090201
Title: Blocking the hedgehog pathway inhibits hepatoblastoma growth.
Journal: Hepatology (Baltimore, Md.) 20090201
Title: Blocking Ihh signaling pathway inhibits the proliferation and promotes the apoptosis of PSCs.
Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20090201
Title: Cross talk between hedgehog and epithelial-mesenchymal transition pathways in gastric pit cells and in diffuse-type gastric cancers.
Journal: British journal of cancer 20090127
Title: Cathepsin B is a target of Hedgehog signaling in pancreatic cancer.
Journal: Cancer letters 20090118
Title: N-myc alters the fate of preneoplastic cells in a mouse model of medulloblastoma.
Journal: Genes & development 20090115
Title: Antiandrogen exposure in utero disrupts expression of desert hedgehog and insulin-like factor 3 in the developing fetal rat testis.
Journal: Endocrinology 20090101
Title: Human embryonic stem cell differentiation toward regional specific neural precursors.
Journal: Stem cells (Dayton, Ohio) 20090101
Title: Liver cell-derived microparticles activate hedgehog signaling and alter gene expression in hepatic endothelial cells.
Journal: Gastroenterology 20090101
Title: Hedgehog signalling is required for cloacal development in the zebrafish embryo.
Journal: The International journal of developmental biology 20090101
Title: Androgenic regulation of hedgehog signaling pathway components in prostate cancer cells.
Journal: Cell cycle (Georgetown, Tex.) 20090101
Title: [The effects of Hedgehog-Gli 1 signaling pathway on proliferation and apoptosis of hepatic stellate cells].
Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20090101
Title: Frame-shifts of digit identity in bird evolution and Cyclopamine-treated wings.
Journal: Evolution & development 20090101
Title: Paracrine sonic hedgehog signalling by prostate cancer cells induces osteoblast differentiation.
Journal: Molecular cancer 20090101
Title: Mechanisms of KGF mediated signaling in pancreatic duct cell proliferation and differentiation.
Journal: PloS one 20090101
Title: FGF4 and retinoic acid direct differentiation of hESCs into PDX1-expressing foregut endoderm in a time- and concentration-dependent manner.
Journal: PloS one 20090101
Title: The role of hedgehog signaling during gastric regeneration.
Journal: Journal of gastroenterology 20090101
Title: Smoothened adopts multiple active and inactive conformations capable of trafficking to the primary cilium.
Journal: PloS one 20090101
Title: Heterochronic shift in Hox-mediated activation of sonic hedgehog leads to morphological changes during fin development.
Journal: PloS one 20090101
Title: Choosing the right path: enhancement of biologically relevant sets of genes or proteins using pathway structure.
Journal: Genome biology 20090101
Title: Sonic hedgehog: its expression in a healing cornea and its role in neovascularization.
Journal: Molecular vision 20090101
Title: Oligodendrocyte development and the onset of myelination in the human fetal brain.
Journal: Frontiers in neuroanatomy 20090101
Title: Immune regulatory neural stem/precursor cells protect from central nervous system autoimmunity by restraining dendritic cell function.
Journal: PloS one 20090101
Title: Sonic hedgehog promotes porcine oocyte maturation and early embryo development.
Journal: Reproduction, fertility, and development 20090101
Title: Inhibition of p70S6K2 down-regulates Hedgehog/GLI pathway in non-small cell lung cancer cell lines.
Journal: Molecular cancer 20090101
Title: Synthesis of cyclopamine using a biomimetic and diastereoselective approach.
Journal: Angewandte Chemie (International ed. in English) 20090101
Title: Highly efficient differentiation and enrichment of spinal motor neurons derived from human and monkey embryonic stem cells.
Journal: PloS one 20090101
Title: Expression of the glioma-associated oncogene homolog (GLI) 1 in human breast cancer is associated with unfavourable overall survival.
Journal: BMC cancer 20090101
Title: Gli1 maintains cell survival by up-regulating IGFBP6 and Bcl-2 through promoter regions in parallel manner in pancreatic cancer cells.
Journal: Journal of carcinogenesis 20090101
Title: Activation of sonic hedgehog signaling pathway in olfactory neuroblastoma.
Journal: Oncology 20090101
Title: Sonic hedgehog is a chemoattractant for midbrain dopaminergic axons.
Journal: PloS one 20090101
Title: Generation of cortical neurons from mouse embryonic stem cells.
Journal: Nature protocols 20090101
Title: GLI3 repressor controls nephron number via regulation of Wnt11 and Ret in ureteric tip cells.
Journal: PloS one 20090101
Title: Hedgehog pathway responsiveness correlates with the presence of primary cilia on prostate stromal cells.
Journal: BMC developmental biology 20090101
Title: GLI1 is a central mediator of EWS/FLI1 signaling in Ewing tumors.
Journal: PloS one 20090101
Title: Zebrafish con/disp1 reveals multiple spatiotemporal requirements for Hedgehog-signaling in craniofacial development.
Journal: BMC developmental biology 20090101
Title: The sonic hedgehog signaling pathway is reactivated in human renal cell carcinoma and plays orchestral role in tumor growth.
Journal: Molecular cancer 20090101
Title: Fishing for the signals that pattern the face.
Journal: Journal of biology 20090101
Title: Hedgehog signalling in androgen independent prostate cancer.
Journal: European urology 20081201
Title: Stemming cancer: functional genomics of cancer stem cells in solid tumors.
Journal: Stem cell reviews 20081201
Title: Role of hedgehog signaling in ovarian cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20081201
Title: The hedgehog inhibitor cyclopamine induces apoptosis in leukemic cells in vitro.
Journal: Leukemia & lymphoma 20081201
Title: Hedgehog-induced survival of B-cell chronic lymphocytic leukemia cells in a stromal cell microenvironment: a potential new therapeutic target.
Journal: Molecular cancer research : MCR 20081201
Title: Hedgehog signaling during expansion of human pancreatic islet-derived precursors.
Journal: Annals of the New York Academy of Sciences 20081201
Title: Zebrafish dorsal root ganglia neural precursor cells adopt a glial fate in the absence of neurogenin1.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20081119
Title: Semisynthetic cyclopamine analogues as potent and orally bioavailable hedgehog pathway antagonists.
Journal: Journal of medicinal chemistry 20081113
Title: Neuroprotective effect of sonic hedgehog up-regulated in Schwann cells following sciatic nerve injury.
Journal: Journal of neurochemistry 20081101
Title: Toward understanding the development of scleral ossicles in the chicken, Gallus gallus.
Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20081101
Title: Magnetic resonance imaging monitors physiological changes with antihedgehog therapy in pancreatic adenocarcinoma xenograft model.
Journal: Pancreas 20081101
Title: MSX2 stimulates chondrocyte maturation by controlling Ihh expression.
Journal: The Journal of biological chemistry 20081024
Title: Hedgehog inhibition prolongs survival in a genetically engineered mouse model of pancreatic cancer.
Journal: Gut 20081001
Title: Oxysterol-induced osteogenic differentiation of marrow stromal cells is regulated by Dkk-1 inhibitable and PI3-kinase mediated signaling.
Journal: Journal of cellular biochemistry 20081001
Title: Tri-phasic expression of posterior Hox genes during development of pectoral fins in zebrafish: implications for the evolution of vertebrate paired appendages.
Journal: Developmental biology 20081001
Title: An intrinsic mechanism of corticogenesis from embryonic stem cells.
Journal: Nature 20080918
Title: Expansion of Bcr-Abl-positive leukemic stem cells is dependent on Hedgehog pathway activation.
Journal: Cancer cell 20080909
Title: An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer.
Journal: Molecular cancer therapeutics 20080901
Title: Autonomous Hedgehog signalling is undetectable in PC-3 prostate cancer cells.
Journal: Biochemical and biophysical research communications 20080815
Title: Endogenous hedgehog expression contributes to myocardial ischemia-reperfusion-induced injury.
Journal: Experimental biology and medicine (Maywood, N.J.) 20080801
Title: Hedgehog signaling is required for effective regeneration of exocrine pancreas.
Journal: Gastroenterology 20080801
Title: Antitumor activity of extracts and compounds from the rhizomes of Veratrum dahuricum.
Journal: Phytotherapy research : PTR 20080801
Title: Gli1 contributes to the invasiveness of pancreatic cancer through matrix metalloproteinase-9 activation.
Journal: Cancer science 20080701
Title: Dose- and route-dependent teratogenicity, toxicity, and pharmacokinetic profiles of the hedgehog signaling antagonist cyclopamine in the mouse.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20080701
Title: Initiation and patterning of the snake dentition are dependent on Sonic hedgehog signaling.
Journal: Developmental biology 20080701
Title: Zebrafish blowout provides genetic evidence for Patched1-mediated negative regulation of Hedgehog signaling within the proximal optic vesicle of the vertebrate eye.
Journal: Developmental biology 20080701
Title: Hedgehog signaling is critical for maintenance of the adult coronary vasculature in mice.
Journal: The Journal of clinical investigation 20080701
Title: Down-regulation of hedgehog-interacting protein through genetic and epigenetic alterations in human hepatocellular carcinoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080615
Title: Survival and function of human thymic dendritic cells are dependent on autocrine Hedgehog signaling.
Journal: Journal of leukocyte biology 20080601
Title: Sonic hedgehog derived from human pancreatic cancer cells augments angiogenic function of endothelial progenitor cells.
Journal: Cancer science 20080601
Title: Hh and Wnt signaling regulate formation of olig2+ neurons in the zebrafish cerebellum.
Journal: Developmental biology 20080601
Title: Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy.
Journal: Development (Cambridge, England) 20080601
Title: Endoderm-derived Sonic hedgehog and mesoderm Hand2 expression are required for enteric nervous system development in zebrafish.
Journal: Developmental biology 20080601
Title: Hedgehog signal activation in oesophageal cancer patients undergoing neoadjuvant chemoradiotherapy.
Journal: British journal of cancer 20080520
Title: Vsx2/Chx10 ensures the correct timing and magnitude of Hedgehog signaling in the mouse retina.
Journal: Developmental biology 20080515
Title: ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification.
Journal: Cell stem cell 20080508
Title: Cyclopamine treatment of full-blown Hh/Ptch-associated RMS partially inhibits Hh/Ptch signaling, but not tumor growth.
Journal: Molecular carcinogenesis 20080501
Title: Characterization of bipotential epidermal progenitors derived from human sebaceous gland: contrasting roles of c-Myc and beta-catenin.
Journal: Stem cells (Dayton, Ohio) 20080501
Title: Patched1 haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity.
Journal: Developmental cell 20080501
Title: Hypoxia-induced compensatory effect as related to Shh and HIF-1alpha in ischemia embryo rat heart.
Journal: Molecular and cellular biochemistry 20080401
Title: Different effects of anti-sonic hedgehog antibodies and the hedgehog pathway inhibitor cyclopamine on generation of dopaminergic neurons from neurospheres of mesencephalic precursors.
Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20080401
Title: Targeted inhibition of hedgehog signaling by cyclopamine prodrugs for advanced prostate cancer.
Journal: Bioorganic & medicinal chemistry 20080315
Title: A hedgehog homolog is involved in muscle formation and organization of Sepia officinalis (mollusca) mantle.
Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20080301
Title: Cancer metastasis as disrupted developmental phenotype.
Journal: Current genomics 20080301
Title: Synthesis and anticancer activity studies of cyclopamine derivatives.
Journal: Bioorganic & medicinal chemistry letters 20080215
Title: Smarcd3 regulates the timing of zebrafish myogenesis onset.
Journal: The Journal of biological chemistry 20080208
Title: Cyclopamine inhibition of the sonic hedgehog pathway in the stomach requires concomitant acid inhibition.
Journal: Regulatory peptides 20080207
Title: CNS-derived glia ensheath peripheral nerves and mediate motor root development.
Journal: Nature neuroscience 20080201
Title: New developments in medulloblastoma treatment: the potential of a cyclopamine-lovastatin combination.
Journal: Expert opinion on investigational drugs 20080201
Title: Commercially available recombinant sonic hedgehog up-regulates Ptc and modulates the cytokine and chemokine expression of human macrophages: an effect mediated by endotoxin contamination?
Journal: Immunobiology 20080101
Title: The vitamin D receptor is a Wnt effector that controls hair follicle differentiation and specifies tumor type in adult epidermis.
Journal: PloS one 20080101
Title: Muscarinic signaling influences the patterning and phenotype of cholinergic amacrine cells in the developing chick retina.
Journal: BMC developmental biology 20080101
Title: Genetic analysis of the two zebrafish patched homologues identifies novel roles for the hedgehog signaling pathway.
Journal: BMC developmental biology 20080101
Title: Inhibition of androgen-independent prostate cancer cell growth is enhanced by combination therapy targeting Hedgehog and ErbB signalling.
Journal: Cancer cell international 20080101
Title: Identification of a novel retinoid by small molecule screening with zebrafish embryos.
Journal: PloS one 20080101
Title: Isolation, purification, and full NMR assignments of cyclopamine from Veratrum californicum.
Journal: Chemistry Central journal 20080101
Title: A periodic pattern generator for dental diversity.
Journal: BMC biology 20080101
Title: Breast cancer stem cells: implications for therapy of breast cancer.
Journal: Breast cancer research : BCR 20080101
Title: Differential screening identifies transcripts with depot-dependent expression in white adipose tissues.
Journal: BMC genomics 20080101
Title: Establishment and characterization of immortalized Gli-null mouse embryonic fibroblast cell lines.
Journal: BMC cell biology 20080101
Title: Distinct roles of Shh and Fgf signaling in regulating cell proliferation during zebrafish pectoral fin development.
Journal: BMC developmental biology 20080101
Title: Musashi1 modulates cell proliferation genes in the medulloblastoma cell line Daoy.
Journal: BMC cancer 20080101
Title: Hedgehog signaling is essential for normal wound healing.
Journal: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20080101
Title: Hedgehog signaling pathway is inactive in colorectal cancer cell lines.
Journal: International journal of cancer 20071215
Title: Urothelial sonic hedgehog signaling plays an important role in bladder smooth muscle formation.
Journal: Differentiation; research in biological diversity 20071201
Title: Identification and characterization of several dietary alkaloids as weak inhibitors of hedgehog signaling.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20071201
Title: The foxa2 gene controls the birth and spontaneous degeneration of dopamine neurons in old age.
Journal: PLoS biology 20071201
Title: Improvement of cytotoxic effects induced by mitoxantrone on hormone-refractory metastatic prostate cancer cells by co-targeting epidermal growth factor receptor and hedgehog signaling cascades.
Journal: Growth factors (Chur, Switzerland) 20071201
Title: Sonic hedgehog promotes stem-cell potential of Müller glia in the mammalian retina.
Journal: Biochemical and biophysical research communications 20071116
Title: The Sonic hedgehog pathway mediates carbamylated erythropoietin-enhanced proliferation and differentiation of adult neural progenitor cells.
Journal: The Journal of biological chemistry 20071102
Title: 20(S)-hydroxycholesterol inhibits PPARgamma expression and adipogenic differentiation of bone marrow stromal cells through a hedgehog-dependent mechanism.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20071101
Title: Correlations between the Sonic Hedgehog pathway and basal cell carcinoma.
Journal: International journal of dermatology 20071101
Title: The hedgehog pathway inhibitor cyclopamine increases levels of p27, and decreases both expression of IGF-II and activation of Akt in PC-3 prostate cancer cells.
Journal: Cancer letters 20071008
Title: Unmasking of epigenetically silenced genes reveals DNA promoter methylation and reduced expression of PTCH in breast cancer.
Journal: Breast cancer research and treatment 20071001
Title: Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma.
Journal: Stem cells (Dayton, Ohio) 20071001
Title: Inhibition of osteosarcoma cell proliferation by the Hedgehog-inhibitor cyclopamine.
Journal: Journal of chemotherapy (Florence, Italy) 20071001
Title: Sonic hedgehog carried by microparticles corrects endothelial injury through nitric oxide release.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070901
Title: Molecular changes associated with teratogen-induced cyclopia.
Journal: Birth defects research. Part A, Clinical and molecular teratology 20070901
Title: Sonic hedgehog promotes proliferation and differentiation of adult muscle cells: Involvement of MAPK/ERK and PI3K/Akt pathways.
Journal: Biochimica et biophysica acta 20070901
Title: Snail and Sonic Hedgehog activation in neuroendocrine tumors of the ileum.
Journal: Endocrine-related cancer 20070901
Title: Extended exposure to Sonic hedgehog is required for patterning the posterior digits of the vertebrate limb.
Journal: Developmental biology 20070815
Title: The hedgehog signaling pathway in the mouse ovary.
Journal: Biology of reproduction 20070801
Title: Essential role of stromally induced hedgehog signaling in B-cell malignancies.
Journal: Nature medicine 20070801
Title: Blockade of sonic hedgehog signal pathway enhances antiproliferative effect of EGFR inhibitor in pancreatic cancer cells.
Journal: Acta pharmacologica Sinica 20070801
Title: Induction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo.
Journal: Cancer research 20070715
Title: [New therapeutic target of breast cancer].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20070628
Title: Hedgehog signaling regulates the amount of hypaxial muscle development during Xenopus myogenesis.
Journal: Developmental biology 20070415
Title: Selective down-regulation of glioma-associated oncogene 2 inhibits the proliferation of hepatocellular carcinoma cells.
Journal: Cancer research 20070415
Title: Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line.
Journal: Cancer research 20070415
Title: Dual blockade of the Hedgehog and ERK1/2 pathways coordinately decreases proliferation and survival of cholangiocarcinoma cells.
Journal: Journal of cancer research and clinical oncology 20070401
Title: Characterization of a novel ectodermal signaling center regulating Tbx2 and Shh in the vertebrate limb.
Journal: Developmental biology 20070401
Title: The prethalamus is established during gastrulation and influences diencephalic regionalization.
Journal: PLoS biology 20070401
Title: Expression of Wsb2 in the developing and adult mouse testis.
Journal: Reproduction (Cambridge, England) 20070401
Title: Oxysterols are novel activators of the hedgehog signaling pathway in pluripotent mesenchymal cells.
Journal: The Journal of biological chemistry 20070323
Title: Sonic hedgehog inversely regulates the expression of angiopoietin-1 and angiopoietin-2 in fibroblasts.
Journal: International journal of molecular medicine 20070301
Title: Hedgehog signaling in the prostate.
Journal: The Journal of urology 20070301
Title: Lack of demonstrable autocrine hedgehog signaling in human prostate cancer cell lines.
Journal: The Journal of urology 20070301
Title: Overexpression of hedgehog signaling molecules and its involvement in the proliferation of endometrial carcinoma cells.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070301
Title: Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers.
Journal: Cancer research 20070301
Title: Combined targeting of epidermal growth factor receptor and hedgehog signaling by gefitinib and cyclopamine cooperatively improves the cytotoxic effects of docetaxel on metastatic prostate cancer cells.
Journal: Molecular cancer therapeutics 20070301
Title: Lovastatin and cyclopamine combination in medulloblastoma.
Journal: Cancer biology & therapy 20070201
Title: HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity.
Journal: Current biology : CB 20070123
Title: Hedgehog signal pathway is activated in ovarian carcinomas, correlating with cell proliferation: it's inhibition leads to growth suppression and apoptosis.
Journal: Cancer science 20070101
Title: Inhibition of Sonic hedgehog signaling leads to posterior digit loss in Ambystoma mexicanum: parallels to natural digit reduction in urodeles.
Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20070101
Title: Hedgehog signaling pathway is a possible therapeutic target for gastric cancer.
Journal: Journal of surgical oncology 20070101
Title: Abnormal hair development and apparent follicular transformation to mammary gland in the absence of hedgehog signaling.
Journal: Developmental cell 20070101
Title: Hedgehog signaling promotes medulloblastoma survival via Bc/II.
Journal: The American journal of pathology 20070101
Title: Holoprosencephaly.
Journal: Orphanet journal of rare diseases 20070101
Title: Systems biology by the rules: hybrid intelligent systems for pathway modeling and discovery.
Journal: BMC systems biology 20070101
Title: The disarrayed mutation results in cell cycle and neurogenesis defects during retinal development in zebrafish.
Journal: BMC developmental biology 20070101
Title: Stromal derived factor-1 exerts differential regulation on distinct cortical cell populations in vitro.
Journal: BMC developmental biology 20070101
Title: Role of stem cells in cancer therapy and cancer stem cells: a review.
Journal: Cancer cell international 20070101
Title: Common molecular pathways involved in human CD133+/CD34+ progenitor cell expansion and cancer.
Journal: Cancer cell international 20070101
Title: Hedgehog signaling patterns the outgrowth of unpaired skeletal appendages in zebrafish.
Journal: BMC developmental biology 20070101
Title: Hedgehog signaling in the murine melanoma microenvironment.
Journal: Angiogenesis 20070101
Title: Prediction of potential drug targets based on simple sequence properties.
Journal: BMC bioinformatics 20070101
Title: Factors that regulate embryonic gustatory development.
Journal: BMC neuroscience 20070101
Title: Indian hedgehog signaling pathway differences between swarm rat chondrosarcoma and native rat chondrocytes.
Journal: The Iowa orthopaedic journal 20070101
Title: Transcriptional profiling of inductive mesenchyme to identify molecules involved in prostate development and disease.
Journal: Genome biology 20070101
Title: Common activation of canonical Wnt signaling in pancreatic adenocarcinoma.
Journal: PloS one 20070101
Title: Manipulation of hedgehog signaling in Xenopus by means of embryo microinjection and application of chemical inhibitors.
Journal: Methods in molecular biology (Clifton, N.J.) 20070101
Title: Cyclopamine treatment of human embryonic stem cells followed by culture in human astrocyte medium promotes differentiation into nestin- and GFAP-expressing astrocytic lineage.
Journal: Life sciences 20061214
Title: Cyclopamine increases the cytotoxic effects of paclitaxel and radiation but not cisplatin and gemcitabine in Hedgehog expressing pancreatic cancer cells.
Journal: Cancer chemotherapy and pharmacology 20061201
Title: Characterization of Xenopus digits and regenerated limbs of the froglet.
Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20061201
Title: Suppressing Wnt signaling by the hedgehog pathway through sFRP-1.
Journal: The Journal of biological chemistry 20061124
Title: Zebrafish cypher is important for somite formation and heart development.
Journal: Developmental biology 20061115
Title: Regulation of Gremlin expression in the posterior limb bud.
Journal: Developmental biology 20061101
Title: Sonic Hedgehog-Gli1 signaling pathway might become an effective therapeutic target in gastrointestinal neuroendocrine carcinomas.
Journal: Cancer biology & therapy 20061101
Title: Identification and characterization of Hedgehog modulator properties after functional coupling of Smoothened to G15.
Journal: Biochemical and biophysical research communications 20061020
Title: Inhibition of the anti-adipogenic Hedgehog signaling pathway by cyclopamine does not trigger adipocyte differentiation.
Journal: Biochemical and biophysical research communications 20061020
Title: Role of small bioorganic molecules in stem cell differentiation to insulin-producing cells.
Journal: Bioorganic & medicinal chemistry 20061001
Title: Development of in vitro techniques for the important medicinal plant Veratrum californicum.
Journal: Planta medica 20061001
Title: Human receptors patched and smoothened partially transduce hedgehog signal when expressed in Drosophila cells.
Journal: The Journal of biological chemistry 20060929
Title: Bone morphogenetic proteins and noggin: inhibiting and inducing fungiform taste papilla development.
Journal: Developmental biology 20060901
Title: Long-term establishment, characterization and manipulation of cell lines from mouse basal cell carcinoma tumors.
Journal: Experimental dermatology 20060901
Title: Targeting the hedgehog signaling pathway with small molecules.
Journal: Anti-cancer agents in medicinal chemistry 20060901
Title: Cyclopamine: inhibiting hedgehog in the treatment of psoriasis.
Journal: Cutis 20060901
Title: PPARbeta/delta regulates paneth cell differentiation via controlling the hedgehog signaling pathway.
Journal: Gastroenterology 20060801
Title: Repression of smoothened by patched-dependent (pro-)vitamin D3 secretion.
Journal: PLoS biology 20060801
Title: Epidermal growth factor receptor and hedgehog signaling pathways are active in esophageal cancer cells from rat reflux model.
Journal: The Journal of surgical research 20060701
Title: Unique and complimentary activities of the Gli transcription factors in Hedgehog signaling.
Journal: Experimental cell research 20060701
Title: Role of sonic hedgehog in maintaining a pool of proliferating stem cells in the human fetal epidermis.
Journal: Human reproduction (Oxford, England) 20060701
Title: Functional compensation in Hedgehog signaling during mouse prostate development.
Journal: Developmental biology 20060701
Title: Hedgehog signal activation in gastric pit cell and in diffuse-type gastric cancer.
Journal: Gastroenterology 20060701
Title: Defects in aortic fusion and craniofacial vasculature in the holoprosencephalic mouse embryo under inhibition of sonic hedgehog signaling.
Journal: The Journal of craniofacial surgery 20060701
Title: Biology-driven diversity: concept of focused diversity.
Journal: Chemical biology & drug design 20060701
Title: Impairment of lower jaw growth in developing zebrafish exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin and reduced hedgehog expression.
Journal: Aquatic toxicology (Amsterdam, Netherlands) 20060615
Title: Sonic hedgehog stimulates the proliferation of rat gastric mucosal cells through ERK activation by elevating intracellular calcium concentration.
Journal: Biochemical and biophysical research communications 20060602
Title: Hedgehog signaling in small-cell lung cancer: frequent in vivo but a rare event in vitro.
Journal: Lung cancer (Amsterdam, Netherlands) 20060601
Title: Hedgehog signaling and response to cyclopamine differ in epithelial and stromal cells in benign breast and breast cancer.
Journal: Cancer biology & therapy 20060601
Title: Developmental signalling pathways in lung cancer.
Journal: Respirology (Carlton, Vic.) 20060501
Title: Activation of glucagon-like peptide-1 receptor signaling does not modify the growth or apoptosis of human pancreatic cancer cells.
Journal: Diabetes 20060501
Title: Dysregulation of the Hedgehog pathway in human hepatocarcinogenesis.
Journal: Carcinogenesis 20060401
Title: Hedgehog signaling controls thymocyte progenitor homeostasis and differentiation in the thymus.
Journal: Nature immunology 20060401
Title: Psoriatic skin expresses the transcription factor Gli1: possible contribution of decreased neurofibromin expression.
Journal: The British journal of dermatology 20060401
Title: Useful plants of dermatology. VIII. The false hellebore (Veratrum californicum).
Journal: Journal of the American Academy of Dermatology 20060401
Title: Inhibition of ocular neovascularization by hedgehog blockade.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20060301
Title: Critical time window of hedgehog-dependent angiogenesis in murine yolk sac.
Journal: Microvascular research 20060301
Title: Early Hedgehog signaling from neural to oral epithelium organizes anterior craniofacial development.
Journal: Development (Cambridge, England) 20060301
Title: Cytotoxic effects induced by a combination of cyclopamine and gefitinib, the selective hedgehog and epidermal growth factor receptor signaling inhibitors, in prostate cancer cells.
Journal: International journal of cancer 20060215
Title: Inhibition of GLI1 gene activation by Patched1.
Journal: The Biochemical journal 20060215
Title: Sonic hedgehog promotes mouse inner ear progenitor cell proliferation and hair cell generation in vitro.
Journal: Neuroreport 20060206
Title: GLI3-dependent transcriptional repression of Gli1, Gli2 and kidney patterning genes disrupts renal morphogenesis.
Journal: Development (Cambridge, England) 20060201
Title: Hedgehog signaling is activated in subsets of esophageal cancers.
Journal: International journal of cancer 20060101
Title: Sonic hedgehog pathway inhibition alters epididymal function as assessed by the development of sperm motility.
Journal: Journal of andrology 20060101
Title: Hedgehog signaling in human hepatocellular carcinoma.
Journal: Cancer biology & therapy 20060101
Title: Agonizing hedgehog.
Journal: Nature chemical biology 20060101
Title: Purmorphamine activates the Hedgehog pathway by targeting Smoothened.
Journal: Nature chemical biology 20060101
Title: RCAS-RNAi: a loss-of-function method for the developing chick retina.
Journal: BMC developmental biology 20060101
Title: Perlecan, a candidate gene for the CAPB locus, regulates prostate cancer cell growth via the Sonic Hedgehog pathway.
Journal: Molecular cancer 20060101
Title: Cross-platform expression profiling demonstrates that SV40 small tumor antigen activates Notch, Hedgehog, and Wnt signaling in human cells.
Journal: BMC cancer 20060101
Title: Cancer stem cells and therapeutic perspectives.
Journal: Current medicinal chemistry 20060101
Title: Treatment of eyelid epithelial neoplasm by targeting sonic hedgehog signaling: an experimental study.
Journal: Japanese journal of ophthalmology 20060101
Title: Gli-1 expression is associated with lymph node metastasis and tumor progression in esophageal squamous cell carcinoma.
Journal: Oncology 20060101
Title: Wnt and Hedgehog are critical mediators of cigarette smoke-induced lung cancer.
Journal: PloS one 20060101
Title: Expression and function of sonic hedgehog pathway components in pituitary adenomas: evidence for a direct role in hormone secretion and cell proliferation.
Journal: The Journal of clinical endocrinology and metabolism 20051201
Title: Migration from a mitogenic niche promotes cell-cycle exit.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20051109
Title: Role for hedgehog signaling in hepatic stellate cell activation and viability.
Journal: Laboratory investigation; a journal of technical methods and pathology 20051101
Title: Teratogens as anti-cancer drugs.
Journal: Cell cycle (Georgetown, Tex.) 20051101
Title: Vertebrate Smoothened functions at the primary cilium.
Journal: Nature 20051013
Title: Recruitment of the Sonic hedgehog signalling cascade in electroconvulsive seizure-mediated regulation of adult rat hippocampal neurogenesis.
Journal: The European journal of neuroscience 20051001
Title: Hedgehog signaling pathway as a therapeutic target in breast cancer.
Journal: Cancer letters 20050928
Title: Hedgehog signaling is required for cranial neural crest morphogenesis and chondrogenesis at the midline in the zebrafish skull.
Journal: Development (Cambridge, England) 20050901
Title: Hedgehog signaling in mouse ovary: Indian hedgehog and desert hedgehog from granulosa cells induce target gene expression in developing theca cells.
Journal: Endocrinology 20050801
Title: Pleiotropic effects of sonic hedgehog on muscle satellite cells.
Journal: Cellular and molecular life sciences : CMLS 20050801
Title: The zebrafish mutants dre, uki, and lep encode negative regulators of the hedgehog signaling pathway.
Journal: PLoS genetics 20050801
Title: Sonic hedgehog signaling regulates the expression of insulin-like growth factor binding protein-6 during fetal prostate development.
Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20050701
Title: Hedgehog signaling controls dorsoventral patterning, blastema cell proliferation and cartilage induction during axolotl tail regeneration.
Journal: Development (Cambridge, England) 20050701
Title: Gli function is essential for motor neuron induction in zebrafish.
Journal: Developmental biology 20050615
Title: Staggered cell-intrinsic timing of ath5 expression underlies the wave of ganglion cell neurogenesis in the zebrafish retina.
Journal: Development (Cambridge, England) 20050601
Title: Angiogenesis within the developing mouse neural tube is dependent on sonic hedgehog signaling: possible roles of motor neurons.
Journal: Genes to cells : devoted to molecular & cellular mechanisms 20050601
Title: Hedgehog signaling in normal urothelial cells and in urothelial carcinoma cell lines.
Journal: Journal of cellular physiology 20050501
Title: Sonic hedgehog regulates proliferation of the retinal ciliary marginal zone in posthatch chicks.
Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20050501
Title: COUP-TFII is essential for radial and anteroposterior patterning of the stomach.
Journal: Development (Cambridge, England) 20050501
Title: Interference with HH-GLI signaling inhibits prostate cancer.
Journal: Trends in molecular medicine 20050501
Title: Regulation and function of the sonic hedgehog signal transduction pathway in isolated gastric parietal cells.
Journal: The Journal of biological chemistry 20050422
Title: Sonic hedgehog has a dual effect on the growth of retinal ganglion axons depending on its concentration.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050330
Title: Basal cell nevus syndrome.
Journal: Current opinion in oncology 20050301
Title: Hedgehog signaling is required for adult blood stem cell formation in zebrafish embryos.
Journal: Developmental cell 20050301
Title: Sonic hedgehog guides commissural axons along the longitudinal axis of the spinal cord.
Journal: Nature neuroscience 20050301
Title: In vivo inhibition of endogenous brain tumors through systemic interference of Hedgehog signaling in mice.
Journal: Mechanisms of development 20050201
Title: Sonic hedgehog is produced by follicular dendritic cells and protects germinal center B cells from apoptosis.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20050201
Title: Sonic hedgehog controls stem cell behavior in the postnatal and adult brain.
Journal: Development (Cambridge, England) 20050101
Title: Hedgehog signaling and cell cycle control in differentiating erythroid progenitors.
Journal: Blood cells, molecules & diseases 20050101
Title: Craniofacial anomalies of the cultured mouse embryo induced by inhibition of sonic hedgehog signaling: an animal model of holoprosencephaly.
Journal: The Journal of craniofacial surgery 20050101
Title: The Hedgehog signaling pathway as a target for anticancer drug discovery.
Journal: Current topics in medicinal chemistry 20050101
Title: Mammary stem cells, self-renewal pathways, and carcinogenesis.
Journal: Breast cancer research : BCR 20050101
Title: Meckel's cartilage differentiation is dependent on hedgehog signaling.
Journal: Cells, tissues, organs 20050101
Title: Differential range and activity of various forms of the Hedgehog protein.
Journal: BMC developmental biology 20050101
Title: ABC transporters as multidrug resistance mechanisms and the development of chemosensitizers for their reversal.
Journal: Cancer cell international 20050101
Title: Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2.
Journal: Science (New York, N.Y.) 20041224
Title: Sonic hedgehog exerts distinct, stage-specific effects on tongue and taste papilla development.
Journal: Developmental biology 20041215
Title: Spatial and temporal regulation of ventral spinal cord precursor specification by Hedgehog signaling.
Journal: Development (Cambridge, England) 20041201
Title: Retinoic-acid-concentration-dependent acquisition of neural cell identity during in vitro differentiation of mouse embryonic stem cells.
Journal: Developmental biology 20041101
Title: Inhibition of smoothened signaling prevents ultraviolet B-induced basal cell carcinomas through regulation of Fas expression and apoptosis.
Journal: Cancer research 20041015
Title: Hedgehog signalling in prostate regeneration, neoplasia and metastasis.
Journal: Nature 20041007
Title: Evidence for a molecular mechanism of teratogenicity of SB-236057, a 5-HT1B receptor inverse agonist that alters axial formation.
Journal: Birth defects research. Part A, Clinical and molecular teratology 20041001
Title: Androgen dependent development of a modified anal fin, gonopodium, as a model to understand the mechanism of secondary sexual character expression in vertebrates.
Journal: FEBS letters 20040924
Title: Hedgehog signalling in foregut malignancy.
Journal: Biochemical pharmacology 20040915
Title: The upregulated expression of sonic hedgehog in motor neurons after rat facial nerve axotomy.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040908
Title: Hedgehog and Fgf signaling pathways regulate the development of tphR-expressing serotonergic raphe neurons in zebrafish embryos.
Journal: Journal of neurobiology 20040905
Title: Purmorphamine induces osteogenesis by activation of the hedgehog signaling pathway.
Journal: Chemistry & biology 20040901
Title: Temporal perturbations in sonic hedgehog signaling elicit the spectrum of holoprosencephaly phenotypes.
Journal: The Journal of clinical investigation 20040816
Title: Sonic Hedgehog functions by localizing the region of proliferation in early developing feather buds.
Journal: Developmental biology 20040801
Title: Signaling dynamics of feather tract formation from the chick somatopleure.
Journal: Development (Cambridge, England) 20040801
Title: Hedgehog signalling in colorectal tumour cells: induction of apoptosis with cyclopamine treatment.
Journal: International journal of cancer 20040720
Title: Indian hedgehog signaling pathway: expression and regulation in pancreatic cancer.
Journal: International journal of cancer 20040710
Title: Biomedical applications of poisonous plant research.
Journal: Journal of agricultural and food chemistry 20040602
Title: Sonic hedgehog signaling regulates Gli3 processing, mesenchymal proliferation, and differentiation during mouse lung organogenesis.
Journal: Developmental biology 20040601
Title: Transforming growth factor (TGF)beta, fibroblast growth factor (FGF) and retinoid signalling pathways promote pancreatic exocrine gene expression in mouse embryonic stem cells.
Journal: The Biochemical journal 20040501
Title: Shh-dependent differentiation of intestinal tissue from embryonic pancreas by activin A.
Journal: Journal of cell science 20040415
Title: Sonic hedgehog signaling plays an essential role during embryonic salivary gland epithelial branching morphogenesis.
Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20040401
Title: Roles for Hedgehog signaling in androgen production and prostate ductal morphogenesis.
Journal: Developmental biology 20040315
Title: Cooperation between sonic hedgehog and fibroblast growth factor/MAPK signalling pathways in neocortical precursors.
Journal: Development (Cambridge, England) 20040301
Title: Hedgehog--Gli signaling in brain tumors: stem cells and paradevelopmental programs in cancer.
Journal: Cancer letters 20040220
Title: A role of activated Sonic hedgehog signaling for the cellular proliferation of oral squamous cell carcinoma cell line.
Journal: Biochemical and biophysical research communications 20040206
Title: Molecular neuro-oncology and development of targeted therapeutic strategies for brain tumors. Part 2: PI3K/Akt/PTEN, mTOR, SHH/PTCH and angiogenesis.
Journal: Expert review of anticancer therapy 20040201
Title: Targeting Sonic Hedgehog: a new way to mow down pancreatic cancer?
Journal: Cancer biology & therapy 20040201
Title: Gene-teratogen interactions in chemically induced congenital malformations.
Journal: Biology of the neonate 20040101
Title: Induction of the differentiation and apoptosis of tumor cells in vivo with efficiency and selectivity.
Journal: European journal of dermatology : EJD 20040101
Title: Cyclopamine, hedgehog and psoriasis.
Journal: Dermatology (Basel, Switzerland) 20040101
Title: Rapid clearance of psoriatic skin lesions induced by topical cyclopamine. A preliminary proof of concept study.
Journal: Dermatology (Basel, Switzerland) 20040101
Title: Activation of the hedgehog pathway in advanced prostate cancer.
Journal: Molecular cancer 20040101
Title: Sonic hedgehog regulates prostatic growth and epithelial differentiation.
Journal: Developmental biology 20031215
Title: [Cutaneous epithelial tumors. Molecular biology and pathogenesis-based therapy].
Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20031201
Title: FGF-dependent generation of oligodendrocytes by a hedgehog-independent pathway.
Journal: Development (Cambridge, England) 20031201
Title: Hedgehog stimulates only osteoblastic differentiation of undifferentiated KS483 cells.
Journal: Bone 20031201
Title: Hedgehog signaling is directly required for the development of zebrafish dorsal root ganglia neurons.
Journal: Development (Cambridge, England) 20031101
Title: Sonic hedgehog and bone morphogenetic protein regulate interneuron development from dorsal telencephalic progenitors in vitro.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20031029
Title: Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours.
Journal: Nature 20031023
Title: Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis.
Journal: Nature 20031023
Title: Cancer: a twist in a hedgehog's tale.
Journal: Nature 20031023
Title: BMP-2 controls alkaline phosphatase expression and osteoblast mineralization by a Wnt autocrine loop.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20031001
Title: Distribution of Indian hedgehog and its receptors patched and smoothened in human chronic pancreatitis.
Journal: The Journal of endocrinology 20030901
Title: A restrictive role for Hedgehog signalling during otic specification in Xenopus.
Journal: Developmental biology 20030815
Title: Induction of neurogenin-1 expression by sonic hedgehog: Its role in development of trigeminal sensory neurons.
Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20030801
Title: Multiple muscle cell identities induced by distinct levels and timing of hedgehog activity in the zebrafish embryo.
Journal: Current biology : CB 20030715
Title: Major components of the insulin-like growth factor axis are expressed early in chicken embryogenesis, with IGF binding protein ( IGFBP) -5 expression subject to regulation by Sonic Hedgehog.
Journal: Anatomy and embryology 20030701
Title: Extraretinal and retinal hedgehog signaling sequentially regulate retinal differentiation in zebrafish.
Journal: Developmental biology 20030615
Title: Role of Sonic hedgehog signaling in epithelial and mesenchymal development of hair follicles in an organ culture of embryonic mouse skin.
Journal: Development, growth & differentiation 20030601
Title: The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance.
Journal: Cell 20030404
Title: Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development.
Journal: Development (Cambridge, England) 20030401
Title: A novel function for Hedgehog signalling in retinal pigment epithelium differentiation.
Journal: Development (Cambridge, England) 20030401
Title: A hedgehog homolog regulates gut formation in leech (Helobdella).
Journal: Development (Cambridge, England) 20030401
Title: Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer.
Journal: Nature 20030320
Title: Disruption of sonic hedgehog signaling alters growth and patterning of lingual taste papillae.
Journal: Developmental biology 20030315
Title: Sonic hedgehog induces capillary morphogenesis by endothelial cells through phosphoinositide 3-kinase.
Journal: The Journal of biological chemistry 20030307
Title: Unique and conserved aspects of gut development in zebrafish.
Journal: Developmental biology 20030301
Title: Cyclopamine and jervine in embryonic rat tongue cultures demonstrate a role for Shh signaling in taste papilla development and patterning: fungiform papillae double in number and form in novel locations in dorsal lingual epithelium.
Journal: Developmental biology 20030201
Title: Multiple roles for Hedgehog signaling in zebrafish pituitary development.
Journal: Developmental biology 20030201
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