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4640-01-1,MFCD04039700
Catalog No.:AA00D90G

4640-01-1 | Triclosan methyl ether

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1g
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5g
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00D90G
Chemical Name:
Triclosan methyl ether
CAS Number:
4640-01-1
Molecular Formula:
C13H9Cl3O2
Molecular Weight:
303.5684
MDL Number:
MFCD04039700
SMILES:
COc1cc(Cl)ccc1Oc1ccc(cc1Cl)Cl
Properties
Computed Properties
 
Complexity:
265  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
5.5  

Downstream Synthesis Route

[1]OrganicMassSpectrometry,1985,vol.20,p.122-133

[2]EnvironmentalScienceandTechnology,2004,vol.38,p.390-395

[3]AnalyticalChemistry,2006,vol.78,p.6542-6546

[1]BiomedicalMassSpectrometry,1978,vol.5,p.224-231

[1]BioorganicandMedicinalChemistryLetters,2013,vol.23,p.1022-1025

Literature

Title: LINE-1 gene hypomethylation and p16 gene hypermethylation in HepG2 cells induced by low-dose and long-term triclosan exposure: The role of hydroxyl group.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20160801

Title: Slow O-demethylation of methyl triclosan to triclosan, which is rapidly glucuronidated and sulfonated in channel catfish liver and intestine.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20121115

Title: Metabolization of the bacteriostatic agent triclosan in edible plants and its consequences for plant uptake assessment.

Journal: Environmental science & technology 20121002

Title: In vitro effects of triclosan and methyl-triclosan on the marine gastropod Haliotis tuberculata.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20120801

Title: Bioconcentration of triclosan, methyl-triclosan, and triclocarban in the plants and sediments of a constructed wetland.

Journal: Chemosphere 20120701

Title: Fate of triclosan and triclocarban in soil columns with and without biosolids surface application.

Journal: Environmental toxicology and chemistry 20120201

Title: Biodegradation of triclosan in biosolids-amended soils.

Journal: Environmental toxicology and chemistry 20111101

Title: Biodegradation of triclosan and formation of methyl-triclosan in activated sludge under aerobic conditions.

Journal: Chemosphere 20110701

Title: Stir bar sorptive extraction of parabens, triclosan and methyl triclosan from soil, sediment and sludge with in situ derivatization and determination by gas chromatography-mass spectrometry.

Journal: Journal of chromatography. A 20110624

Title: Effects of triclocarban, triclosan, and methyl triclosan on thyroid hormone action and stress in frog and mammalian culture systems.

Journal: Environmental science & technology 20110615

Title: Fully automated determination of parabens, triclosan and methyl triclosan in wastewater by microextraction by packed sorbents and gas chromatography-mass spectrometry.

Journal: Analytica chimica acta 20110117

Title: GC-MS determination of parabens, triclosan and methyl triclosan in water by in situ derivatisation and stir-bar sorptive extraction.

Journal: Analytical and bioanalytical chemistry 20110101

Title: Matrix solid-phase dispersion followed by gas chromatography-mass spectrometry for the determination of triclosan and methyl triclosan in sludge and sediments.

Journal: Analytical and bioanalytical chemistry 20101101

Title: Simultaneous quantitation of parabens, triclosan, and methyl triclosan in indoor house dust using solid phase extraction and gas chromatography-mass spectrometry.

Journal: Journal of environmental monitoring : JEM 20101006

Title: Determination of triclosan and methyl triclosan in environmental solid samples by matrix solid-phase dispersion and gas chromatography-mass spectrometry.

Journal: Journal of separation science 20100901

Title: Identification of methyl triclosan and halogenated analogues in male common carp (Cyprinus carpio) from Las Vegas Bay and semipermeable membrane devices from Las Vegas Wash, Nevada.

Journal: The Science of the total environment 20090301

Title: Snail bioaccumulation of triclocarban, triclosan, and methyltriclosan in a North Texas, USA, stream affected by wastewater treatment plant runoff.

Journal: Environmental toxicology and chemistry 20080801

Title: Assessment of the acute toxicity of triclosan and methyl triclosan in wastewater based on the bioluminescence inhibition of Vibrio fischeri.

Journal: Analytical and bioanalytical chemistry 20080401

Title: Toxicity of the antimicrobial compound triclosan and formation of the metabolite methyl-triclosan in estuarine systems.

Journal: Environmental toxicology 20080401

Title: Algal bioaccumulation of triclocarban, triclosan, and methyl-triclosan in a North Texas wastewater treatment plant receiving stream.

Journal: Chemosphere 20070501

Title: Occurrence of UV filters 4-methylbenzylidene camphor and octocrylene in fish from various Swiss rivers with inputs from wastewater treatment plants.

Journal: Environmental science & technology 20060301

Title: Optimization of solid-phase microextraction conditions for the determination of triclosan and possible related compounds in water samples.

Journal: Journal of chromatography. A 20050422

Title: Xijuan Chen, et al. Biodegradation of triclosan and formation of methyl-triclosan in activated sludge under aerobic conditions. Chemosphere. 2011 Jul;84(4):452-6.

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