Title: Effects of a new synthetic zerumbone pendant derivative (ZPD) on apoptosis induction and anti-migratory effects in human cervical cancer cells.
Journal: Chemico-biological interactions 20171225
Title: Zerumbone reduced the inflammatory response of acute lung injury in endotoxin-treated mice via Akt-NFκB pathway.
Journal: Chemico-biological interactions 20170601
Title: Elevated IL-1β expression induces invasiveness of triple negative breast cancer cells and is suppressed by zerumbone.
Journal: Chemico-biological interactions 20161025
Title: Lipid-lowering effects of zerumbone, a natural cyclic sesquiterpene of Zingiber zerumbet Smith, in high-fat diet-induced hyperlipidemic hamsters.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20140701
Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Journal: Bioorganic & medicinal chemistry 20121115
Title: Antiulcer principle from Zingiber montanum.
Journal: Journal of ethnopharmacology 20120507
Title: Zerumbone attenuates the severity of acute necrotizing pancreatitis and pancreatitis-induced hepatic injury.
Journal: Mediators of inflammation 20120101
Title: Ginger phytochemicals mitigate the obesogenic effects of a high-fat diet in mice: a proteomic and biomarker network analysis.
Journal: Molecular nutrition & food research 20110901
Title: A short-chain dehydrogenase involved in terpene metabolism from Zingiber zerumbet.
Journal: The FEBS journal 20110801
Title: Liquid chromatography-tandem mass spectroscopic method for the determination of zerumbone in human plasma and its application to pharmacokinetics.
Journal: Journal of mass spectrometry : JMS 20110801
Title: Zerumbone induces heme oxygenase-1 expression in mouse skin and cultured murine epidermal cells through activation of Nrf2.
Journal: Cancer prevention research (Philadelphia, Pa.) 20110601
Title: Altered cross-linking of HSP27 by zerumbone as a novel strategy for overcoming HSP27-mediated radioresistance.
Journal: International journal of radiation oncology, biology, physics 20110315
Title: Zingiber zerumbet CYP71BA1 catalyzes the conversion of α-humulene to 8-hydroxy-α-humulene in zerumbone biosynthesis.
Journal: Cellular and molecular life sciences : CMLS 20110301
Title: Zerumbone-induced antinociception: involvement of the L-arginine-nitric oxide-cGMP -PKC-K+ ATP channel pathways.
Journal: Basic & clinical pharmacology & toxicology 20110301
Title: Zerumbone induces apoptosis in T-acute lymphoblastic leukemia cells.
Journal: Leukemia research 20110201
Title: Dietary zerumbone prevents against ultraviolet B-induced cataractogenesis in the mouse.
Journal: Molecular vision 20110101
Title: Dietary zerumbone prevents mouse cornea from UVB-induced photokeratitis through inhibition of NF-κB, iNOS, and TNF-α expression and reduction of MDA accumulation.
Journal: Molecular vision 20110101
Title: Effects of selected food phytochemicals in reducing the toxic actions of TCDD and p,p'-DDT in U937 macrophages.
Journal: Archives of toxicology 20101201
Title: Regression of cervical intraepithelial neoplasia by zerumbone in female Balb/c mice prenatally exposed to diethylstilboestrol: involvement of mitochondria-regulated apoptosis.
Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20100901
Title: Potential chemoprevention of diethylnitrosamine-initiated and 2-acetylaminofluorene-promoted hepatocarcinogenesis by zerumbone from the rhizomes of the subtropical ginger (Zingiber zerumbet).
Journal: Chemico-biological interactions 20100805
Title: Zerumbone enhances TRAIL-induced apoptosis through the induction of death receptors in human colon cancer cells: Evidence for an essential role of reactive oxygen species.
Journal: Cancer research 20090815
Title: Combination of zerumbone and cisplatin to treat cervical intraepithelial neoplasia in female BALB/c mice.
Journal: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20090801
Title: Preliminary analysis of the antinociceptive activity of zerumbone.
Journal: Fitoterapia 20090601
Title: In vitro ultramorphological assessment of apoptosis induced by zerumbone on (HeLa).
Journal: Journal of biomedicine & biotechnology 20090101
Title: Chemoprevention with phytochemicals targeting inducible nitric oxide synthase.
Journal: Forum of nutrition 20090101
Title: Zerumbone down-regulates chemokine receptor CXCR4 expression leading to inhibition of CXCL12-induced invasion of breast and pancreatic tumor cells.
Journal: Cancer research 20081101
Title: Molecular cloning and functional characterization of alpha-humulene synthase, a possible key enzyme of zerumbone biosynthesis in shampoo ginger (Zingiber zerumbet Smith).
Journal: Planta 20080501
Title: Targeting NOX, INOS and COX-2 in inflammatory cells: chemoprevention using food phytochemicals.
Journal: International journal of cancer 20071201
Title: Zerumbone exerts a beneficial effect on inflammatory parameters of cholecystokinin octapeptide-induced experimental pancreatitis but fails to improve histology.
Journal: Pancreas 20071001
Title: Zerumbone suppresses phorbol ester-induced expression of multiple scavenger receptor genes in THP-1 human monocytic cells.
Journal: Bioscience, biotechnology, and biochemistry 20070401
Title: Synthesis of a novel inhibitor against MRSA and VRE: preparation from zerumbone ring opening material showing histidine-kinase inhibition.
Journal: Bioorganic & medicinal chemistry letters 20070215
Title: Citrus nobiletin suppresses bone loss in ovariectomized ddY mice and collagen-induced arthritis in DBA/1J mice: possible involvement of receptor activator of NF-kappaB ligand (RANKL)-induced osteoclastogenesis regulation.
Journal: BioFactors (Oxford, England) 20070101
Title: Zerumbone abolishes NF-kappaB and IkappaBalpha kinase activation leading to suppression of antiapoptotic and metastatic gene expression, upregulation of apoptosis, and downregulation of invasion.
Journal: Oncogene 20051020
Title: Inhibitory actions of several natural products on proliferation of rat vascular smooth muscle cells induced by Hsp60 from Chlamydia pneumoniae J138.
Journal: Journal of agricultural and food chemistry 20041006
Title: Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes.
Journal: FEBS letters 20040813
Title: Zerumbone, a sesquiterpene in subtropical ginger, suppresses skin tumor initiation and promotion stages in ICR mice.
Journal: International journal of cancer 20040701
Title: Sesquiterpenes and flavonol glycosides from Zingiber aromaticum and their CYP3A4 and CYP2D6 inhibitory activities.
Journal: Journal of natural products 20040701
Title: Suppression of dextran sodium sulfate-induced colitis in mice by zerumbone, a subtropical ginger sesquiterpene, and nimesulide: separately and in combination.
Journal: Biochemical pharmacology 20031001
Title: Effects of selected food factors with chemopreventive properties on combined lipopolysaccharide- and interferon-gamma-induced IkappaB degradation in RAW264.7 macrophages.
Journal: Cancer letters 20030530
Title: Antitumor activity of extract of Zingiber aromaticum and its bioactive sesquiterpenoid zerumbone.
Journal: Nutrition and cancer 20030101
Title: Redox-regulated mechanism may account for zerumbone's ability to suppress cancer-cell proliferation.
Journal: Carcinogenesis 20021101
Title: Zerumbone, a Southeast Asian ginger sesquiterpene, markedly suppresses free radical generation, proinflammatory protein production, and cancer cell proliferation accompanied by apoptosis: the alpha,beta-unsaturated carbonyl group is a prerequisite.
Journal: Carcinogenesis 20020501
Title: Chemoprevention of azoxymethane-induced rat aberrant crypt foci by dietary zerumbone isolated from Zingiber zerumbet.
Journal: Life sciences 20010907
Title: Murakami A, et al. Identification of zerumbone in Zingiber zerumbet Smith as a potent inhibitor of 12-O-tetradecanoylphorbol-13-acetate-induced Epstein-Barr virus activation. Biosci Biotechnol Biochem. 1999 Oct;63(10):1811-2.
Title: Kalantari K, et al. A Review of the Biomedical Applications of Zerumbone and the Techniques for Its Extractionfrom Ginger Rhizomes. Molecules. 2017 Sep 30;22(10).
