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486-84-0,MFCD00004957
Catalog No.:AA003QR9

486-84-0 | Harmane

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25mg
95%
in stock  
$54.00   $38.00
- +
100mg
95%
in stock  
$71.00   $50.00
- +
250mg
95%
in stock  
$120.00   $84.00
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1g
≥ 95%
in stock  
$313.00   $219.00
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5g
≥ 95%
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$1,394.00   $976.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003QR9
Chemical Name:
Harmane
CAS Number:
486-84-0
Molecular Formula:
C12H10N2
Molecular Weight:
182.2212
MDL Number:
MFCD00004957
SMILES:
Cc1nccc2c1[nH]c1c2cccc1
NSC Number:
54439
Properties
Properties
 
BP:
386.9°C at 760 mmHg  
Form:
Solid  
MP:
>235ºC (dec.)  
Storage:
2-8℃;Inert atmosphere;  

Computed Properties
 
Complexity:
216  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
XLogP3:
3.6  

Downstream Synthesis Route

[1]Tetrahedron,2016,vol.72,p.5872-5879

[2]TetrahedronLetters,1985,vol.26,p.385-388

486-84-0    56523-59-2   
1-methyl-2-(15-pentadecanoicacid)-2H-pyrido3,4-bindoliumbromide 

[1]JournalofHeterocyclicChemistry,1999,vol.36,p.949-951

[1]Bennasar,M.-Lluisa;Roca,Tomas;Monerris,Manuel[JournalofOrganicChemistry,2004,vol.69,#3,p.752-756]

486-84-0    637-59-2   
9-(3-phenyl)propyl-1-methyl-β-carboline 

[1]Zhang,Guoxian;Cao,Rihui;Guo,Liang;Ma,Qin;Fan,Wenxi;Chen,Xuemei;Li,Jianru;Shao,Guang;Qiu,Liqin;Ren,Zhenghua[EuropeanJournalofMedicinalChemistry,2013,vol.65,p.21-31]

[2]Cao;Chen;Peng;Ma;Hou;Guan;Liu;Xu[EuropeanJournalofMedicinalChemistry,2005,vol.40,#10,p.991-1001]

[3]Locationinpatent:schemeortableChen,Zhiyong;Cao,Rihui;Shi,Buxi;Guo,Liang;Sun,Jie;Ma,Qin;Fan,Wenxi;Song,Huacan[EuropeanJournalofMedicinalChemistry,2011,vol.46,#10,p.5127-5137]

[1]Moehrle,Hans;Dwuletzki,Heinz[ZeitschriftfurNaturforschung,B:ChemicalSciences,1987,vol.42,#8,p.1032-1034]

Literature

Title: From the Cover: Harmane-Induced Selective Dopaminergic Neurotoxicity in Caenorhabditis elegans.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20180201

Title: Monoamine oxidase inhibitory activity in tobacco particulate matter: Are harman and norharman the only physiologically relevant inhibitors?

Journal: Neurotoxicology 20170301

Title: α-Glucosidase inhibitor from Buthus martensi Karsch.

Journal: Food chemistry 20130115

Title: Profiles and concentrations of heterocyclic aromatic amines formed in beef during various heat treatments depend on the time of ripening and muscle type.

Journal: Meat science 20121201

Title: Antioxidant capacity and inhibitory effect of grape seed and rosemary extract in marinades on the formation of heterocyclic amines in fried beef patties.

Journal: Food chemistry 20120915

Title: Structural insights into cholinesterases inhibition by harmane β-carbolinium derivatives: a kinetics-molecular modeling approach.

Journal: Phytochemistry 20120901

Title: Simultaneous determination of alkaloids and flavonoids from aerial parts of Passiflora species and dietary supplements using UPLC-UV-MS and HPTLC.

Journal: Natural product communications 20120901

Title: Binding interaction and rotational-relaxation dynamics of a cancer cell photosensitizer with various micellar assemblies.

Journal: The journal of physical chemistry. B 20120816

Title: Involvement of the cholinergic system of CA1 on harmane-induced amnesia in the step-down passive avoidance test.

Journal: Journal of psychopharmacology (Oxford, England) 20120801

Title: Detection of bioactive exometabolites produced by the filamentous marine cyanobacterium Geitlerinema sp.

Journal: Marine biotechnology (New York, N.Y.) 20120801

Title: Blood harmane (1-methyl-9H-pyrido[3,4-b]indole) concentrations in essential tremor: repeat observation in cases and controls in New York.

Journal: Journal of toxicology and environmental health. Part A 20120615

Title: Molecular phylogeny and species delimitation in the section Longibrachiatum of Trichoderma.

Journal: Fungal genetics and biology : FG & B 20120501

Title: Prospective acetylcholinesterase inhibitory activity of indole and its analogs.

Journal: Bioorganic & medicinal chemistry letters 20120415

Title: Differential interactions of a biological photosensitizer with liposome membranes having varying surface charges.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20120401

Title: Photosensitization of DNA by β-carbolines: kinetic analysis and photoproduct characterization.

Journal: Organic & biomolecular chemistry 20120307

Title: No differences in in vivo kinematics between six different types of knee prostheses.

Journal: Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA 20120301

Title: Predicting lower body power from vertical jump prediction equations for loaded jump squats at different intensities in men and women.

Journal: Journal of strength and conditioning research 20120301

Title: Constructing an index of physical fitness age for Japanese elderly based on 7-year longitudinal data: sex differences in estimated physical fitness age.

Journal: Age (Dordrecht, Netherlands) 20120201

Title: Effects of apomorphine and β-carbolines on firing rate of neurons in the ventral pallidum in the rats.

Journal: Behavioural brain research 20120201

Title: The impact of dihydrogen phosphate anions on the excited-state proton transfer of harmane. Effect of β-cyclodextrin on these photoreactions.

Journal: The journal of physical chemistry. A 20120112

Title: Administration of harmine and imipramine alters creatine kinase and mitochondrial respiratory chain activities in the rat brain.

Journal: Depression research and treatment 20120101

Title: Low-temperature-modulated fruit ripening is independent of ethylene in 'Sanuki Gold' kiwifruit.

Journal: Journal of experimental botany 20120101

Title: Taxon-specific metagenomics of Trichoderma reveals a narrow community of opportunistic species that regulate each other's development.

Journal: Microbiology (Reading, England) 20120101

Title: Rationale for antioxidant supplementation in sarcopenia.

Journal: Journal of aging research 20120101

Title: Old and new ideas for data screening and assumption testing for exploratory and confirmatory factor analysis.

Journal: Frontiers in psychology 20120101

Title: Mitochondrial protection and anti-aging activity of Astragalus polysaccharides and their potential mechanism.

Journal: International journal of molecular sciences 20120101

Title: The Complexity of Sporadic Alzheimer's Disease Pathogenesis: The Role of RAGE as Therapeutic Target to Promote Neuroprotection by Inhibiting Neurovascular Dysfunction.

Journal: International journal of Alzheimer's disease 20120101

Title: Glutathione homeostasis and functions: potential targets for medical interventions.

Journal: Journal of amino acids 20120101

Title: Insulin in central nervous system: more than just a peripheral hormone.

Journal: Journal of aging research 20120101

Title: Testosterone and vascular function in aging.

Journal: Frontiers in physiology 20120101

Title: The assumption of a reliable instrument and other pitfalls to avoid when considering the reliability of data.

Journal: Frontiers in psychology 20120101

Title: Air pollution, oxidative stress, and Alzheimer's disease.

Journal: Journal of environmental and public health 20120101

Title: Healthy aging - insights from Drosophila.

Journal: Frontiers in physiology 20120101

Title: Effects of peroxisomal catalase inhibition on mitochondrial function.

Journal: Frontiers in physiology 20120101

Title: Polysaccharides from the Medicinal Mushroom Cordyceps taii Show Antioxidant and Immunoenhancing Activities in a D-Galactose-Induced Aging Mouse Model.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: Selectionist and evolutionary approaches to brain function: a critical appraisal.

Journal: Frontiers in computational neuroscience 20120101

Title: Pattern Recognition Receptors in HIV Transmission.

Journal: Frontiers in immunology 20120101

Title: An alternative paradigm for the role of antimalarial plants in Africa.

Journal: TheScientificWorldJournal 20120101

Title: Function and Regulation of Lipid Biology in Caenorhabditis elegans Aging.

Journal: Frontiers in physiology 20120101

Title: The neglected significance of 'antioxidative stress'.

Journal: Oxidative medicine and cellular longevity 20120101

Title: Genome-Wide Characterization of ISR Induced in Arabidopsis thaliana by Trichoderma hamatum T382 Against Botrytis cinerea Infection.

Journal: Frontiers in plant science 20120101

Title: Leishmanicidal activity of nine novel flavonoids from Delphinium staphisagria.

Journal: TheScientificWorldJournal 20120101

Title: Successful closed reduction of a dislocated constrained total hip arthroplasty: a case report and literature review.

Journal: The open orthopaedics journal 20120101

Title: Vascular Aging in Women: is Estrogen the Fountain of Youth?

Journal: Frontiers in physiology 20120101

Title: Energy and redox homeostasis in tumor cells.

Journal: International journal of cell biology 20120101

Title: Untangling the Roles of Anti-Apoptosis in Regulating Programmed Cell Death using Humanized Yeast Cells.

Journal: Frontiers in oncology 20120101

Title: Formation of heterocyclic amines during cooking of duck meat.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101

Title: Neonaucline, a new indole alkaloid from the leaves of Ochreinauclea maingayii (Hook. f.) Ridsd. (Rubiaceae).

Journal: Molecules (Basel, Switzerland) 20111228

Title: Inhibition of human cytochrome P450 enzymes 3A4 and 2D6 by β-carboline alkaloids, harmine derivatives.

Journal: Phytotherapy research : PTR 20111101

Title: Protein accumulation in leaves and roots associated with improved drought tolerance in creeping bentgrass expressing an ipt gene for cytokinin synthesis.

Journal: Journal of experimental botany 20111101

Title: Preventing false negatives with high-resolution mass spectrometry: the benzophenone case.

Journal: Rapid communications in mass spectrometry : RCM 20111030

Title: Exploring the strength, mode, dynamics, and kinetics of binding interaction of a cationic biological photosensitizer with DNA: implication on dissociation of the drug-DNA complex via detergent sequestration.

Journal: The journal of physical chemistry. B 20111020

Title: Simiranes A and B: erythroxylanes diterpenes and other compounds from Simira eliezeriana (Rubiaceae).

Journal: Natural product research 20111001

Title: An accurate new method to measure the dimensionless figure of merit of thermoelectric devices based on the complex impedance porcupine diagram.

Journal: The Review of scientific instruments 20111001

Title: Modulation of prototropic activity and rotational relaxation dynamics of a cationic biological photosensitizer within the motionally constrained bio-environment of a protein.

Journal: The journal of physical chemistry. B 20110901

Title: The Arabidopsis phi class glutathione transferase AtGSTF2: binding and regulation by biologically active heterocyclic ligands.

Journal: The Biochemical journal 20110815

Title: A genetic analysis of nitric oxide-mediated signaling during chronological aging in the yeast.

Journal: Biogerontology 20110801

Title: Monoamine oxidase A binding in the prefrontal and anterior cingulate cortices during acute withdrawal from heavy cigarette smoking.

Journal: Archives of general psychiatry 20110801

Title: In vitro and in vivo activities of Peganum harmala extract against Leishmania major.

Journal: Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 20110801

Title: Structure-activity relationships of carboline and carbazole derivatives as a novel class of ATP-competitive kinesin spindle protein inhibitors.

Journal: Journal of medicinal chemistry 20110714

Title: Dietary inhibitors of monoamine oxidase A.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20110701

Title: Jump peak power assessment through power prediction equations in different samples.

Journal: Journal of strength and conditioning research 20110701

Title: The protean toxicities of lead: new chapters in a familiar story.

Journal: International journal of environmental research and public health 20110701

Title: Lesion of the cerebellar noradrenergic innervation enhances the harmaline-induced tremor in rats.

Journal: Cerebellum (London, England) 20110601

Title: Species diversity of Trichoderma in Poland.

Journal: Journal of applied genetics 20110501

Title: Effects of harmane and other β-carbolines on apomorphine-induced licking behavior in rat.

Journal: Pharmacology, biochemistry, and behavior 20110401

Title: Blood harmane, blood lead, and severity of hand tremor: evidence of additive effects.

Journal: Neurotoxicology 20110301

Title: Screening of non-polar heterocyclic amines in urine by microextraction in packed sorbent-fluorimetric detection and confirmation by capillary liquid chromatography.

Journal: Talanta 20110215

Title: SIRT-ain relief from age-inducing stress.

Journal: Aging 20110201

Title: Hazardous compounds in tobacco smoke.

Journal: International journal of environmental research and public health 20110201

Title: Effects of spider venom toxin PWTX-I (6-Hydroxytrypargine) on the central nervous system of rats.

Journal: Toxins 20110201

Title: Positioning effects of KillerRed inside of cells correlate with DNA strand breaks after activation with visible light.

Journal: International journal of medical sciences 20110101

Title: Stress resistance and longevity are not directly linked to levels of enzymatic antioxidants in the ponerine ant Harpegnathos saltator.

Journal: PloS one 20110101

Title: Tolerance of spermatogonia to oxidative stress is due to high levels of Zn and Cu/Zn superoxide dismutase.

Journal: PloS one 20110101

Title: Inspiratory muscle strength training improves weaning outcome in failure to wean patients: a randomized trial.

Journal: Critical care (London, England) 20110101

Title: The role of the mitochondrial genome in ageing and carcinogenesis.

Journal: Journal of aging research 20110101

Title: May 'mitochondrial eve' and mitochondrial haplogroups play a role in neurodegeneration and Alzheimer's disease?

Journal: International journal of Alzheimer's disease 20110101

Title: Hypothesis on the dual origin of the Mammalian subplate.

Journal: Frontiers in neuroanatomy 20110101

Title: Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in wistar rats.

Journal: PloS one 20110101

Title: Metabolism, genomics, and DNA repair in the mouse aging liver.

Journal: Current gerontology and geriatrics research 20110101

Title: β-carboline compounds, including harmine, inhibit DYRK1A and tau phosphorylation at multiple Alzheimer's disease-related sites.

Journal: PloS one 20110101

Title: Posttranslational modification of 6-phosphofructo-1-kinase as an important feature of cancer metabolism.

Journal: PloS one 20110101

Title: The importance of mitochondrial DNA in aging and cancer.

Journal: Journal of aging research 20110101

Title: Zoogeography, taxonomy, and conservation of West Virginia's Ohio River floodplain crayfishes (Decapoda, Cambaridae).

Journal: ZooKeys 20110101

Title: Lack of the delta subunit of RNA polymerase increases virulence related traits of Streptococcus mutans.

Journal: PloS one 20110101

Title: Long-Term Potentiation at CA3-CA1 Hippocampal Synapses with Special Emphasis on Aging, Disease, and Stress.

Journal: Frontiers in aging neuroscience 20110101

Title: Expressed sequence tags from Atta laevigata and identification of candidate genes for the control of pest leaf-cutting ants.

Journal: BMC research notes 20110101

Title: Efficacy of treating pain to reduce behavioural disturbances in residents of nursing homes with dementia: cluster randomised clinical trial.

Journal: BMJ (Clinical research ed.) 20110101

Title: Abdominal compartment syndrome - Intra-abdominal hypertension: Defining, diagnosing, and managing.

Journal: Journal of emergencies, trauma, and shock 20110101

Title: Blood harmane concentrations in 497 individuals relative to coffee, cigarettes, and food consumption on the morning of testing.

Journal: Journal of toxicology 20110101

Title: Mitochondria and aging.

Journal: Journal of aging research 20110101

Title: Comparative Effects of α-, β-, and γ-Carbolines on Platelet Aggregation and Lipid Membranes.

Journal: Journal of toxicology 20110101

Title: Correlation between antibutyrylcholinesterasic and antioxidant activities of three aqueous extracts from Tunisian Rhus pentaphyllum.

Journal: Annals of clinical microbiology and antimicrobials 20110101

Title: MedEval - A Swedish medical test collection with doctors and patients user groups.

Journal: Journal of biomedical semantics 20110101

Title: Are physiological attributes of jockeys predictors of falls? A pilot study.

Journal: BMJ open 20110101

Title: Website quality, expectation, confirmation, and end user satisfaction: the knowledge-intensive website of the Korean National Cancer Information Center.

Journal: Journal of medical Internet research 20110101

Title: Comparative endocrinology of aging and longevity regulation.

Journal: Frontiers in endocrinology 20110101

Title: Visuo-spatial ability in colonoscopy simulator training.

Journal: Advances in health sciences education : theory and practice 20101201

Title: Relationship between blood harmane and harmine concentrations in familial essential tremor, sporadic essential tremor and controls.

Journal: Neurotoxicology 20101201

Title: Interaction of β-carboline alkaloids with RNA.

Journal: DNA and cell biology 20101201

Title: Harman induces CYP1A1 enzyme through an aryl hydrocarbon receptor mechanism.

Journal: Toxicology and applied pharmacology 20101115

Title: Capillary liquid chromatography with diode array and mass spectrometry detection for heterocyclic aromatic amine determination in ready-to-eat food treated with electron-beam irradiation.

Journal: Journal of chromatography. A 20101022

Title: Fractionation and identification of organic nitrogen species from bio-oil produced by fast pyrolysis of sewage sludge.

Journal: Bioresource technology 20101001

Title: Intravaginal and menstrual practices among women working in food and recreational facilities in Mwanza, Tanzania: implications for microbicide trials.

Journal: AIDS and behavior 20101001

Title: Quantitative trait loci associated with longevity of lettuce seeds under conventional and controlled deterioration storage conditions.

Journal: Journal of experimental botany 20101001

Title: Bis(carbonyl-κC)(N,N-dimethyl-thio-carbamoyl-κC,S)(pyridine-2-thiol-ato-κN,S)(triphenyl-phosphine-κP)molybdenum(II).

Journal: Acta crystallographica. Section E, Structure reports online 20101001

Title: Signaling and Damaging Functions of Free Radicals in Aging-Free Radical Theory, Hormesis, and TOR.

Journal: Aging and disease 20101001

Title: Clinical aspects of melatonin intervention in Alzheimer's disease progression.

Journal: Current neuropharmacology 20100901

Title: Association of Angiotensin Converting Enzyme gene Polymorphism and Indian Army Triathletes Performance.

Journal: Asian journal of sports medicine 20100901

Title: Beta-carboline alkaloids bind DNA.

Journal: Journal of photochemistry and photobiology. B, Biology 20100802

Title: Inhibitory effect of marinades with hibiscus extract on formation of heterocyclic aromatic amines and sensory quality of fried beef patties.

Journal: Meat science 20100801

Title: Kinesin spindle protein (KSP) inhibitors with 2,3-fused indole scaffolds.

Journal: Journal of medicinal chemistry 20100708

Title: Lipidomics: a tool for studies of atherosclerosis.

Journal: Current atherosclerosis reports 20100701

Title: Biology and biotechnology of Trichoderma.

Journal: Applied microbiology and biotechnology 20100701

Title: Age-related increase of reactive oxygen generation in the brains of mammals and birds: is reactive oxygen a signaling molecule to determine the aging process and life span?

Journal: Geriatrics & gerontology international 20100701

Title: Simultaneous determination of six non-polar heterocyclic amines in meat samples by supercritical fluid extraction-capillary electrophoresis under fluorimetric detection.

Journal: Electrophoresis 20100701

Title: Successful smoking cessation and duration of abstinence--an analysis of socioeconomic determinants.

Journal: International journal of environmental research and public health 20100701

Title: Transdisciplinarity as an inference technique to achieve a better understanding in the health and environmental sciences.

Journal: International journal of environmental research and public health 20100601

Title: Hexaaqua-magnesium(II) bis-{[2-(1-phenyl-1H-tetra-zol-5-yl)sulfan-yl]acetate}.

Journal: Acta crystallographica. Section E, Structure reports online 20100601

Title: Involvement of dopamine D1/D2 receptors on harmane-induced amnesia in the step-down passive avoidance test.

Journal: European journal of pharmacology 20100525

Title: A class of 3S-2-aminoacyltetrahydro-beta-carboline-3-carboxylic acids: their facile synthesis, inhibition for platelet activation, and high in vivo anti-thrombotic potency.

Journal: Journal of medicinal chemistry 20100422

Title: Thermoelectric characterization by transient Harman method under nonideal contact and boundary conditions.

Journal: The Review of scientific instruments 20100401

Title: Electrophysiological characterization of harmane-induced activation of mesolimbic dopamine neurons.

Journal: European journal of pharmacology 20100310

Title: Electrospray MS-based characterization of beta-carbolines--mutagenic constituents of thermally processed meat.

Journal: Molecular nutrition & food research 20100301

Title: Mitochondrial function as a determinant of life span.

Journal: Pflugers Archiv : European journal of physiology 20100101

Title: A novel 5-HT(2A) receptor antagonist exhibits antidepressant-like effects in a battery of rodent behavioural assays: approaching early-onset antidepressants.

Journal: Pharmacology, biochemistry, and behavior 20100101

Title: [Analysis of aging-related oxidative stress status in normal aging animals and development of anti-aging interventions].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20100101

Title: Curcumin, inflammation, ageing and age-related diseases.

Journal: Immunity & ageing : I & A 20100101

Title: Bacterial adaptation through distributed sensing of metabolic fluxes.

Journal: Molecular systems biology 20100101

Title: Learning at old age: a study on winter bees.

Journal: Frontiers in behavioral neuroscience 20100101

Title: Human direct actions may alter animal welfare, a study on horses (Equus caballus).

Journal: PloS one 20100101

Title: Oxidative stress mediates the pathogenic effect of different Alzheimer's disease risk factors.

Journal: Frontiers in aging neuroscience 20100101

Title: Differential expression of maize chitinases in the presence or absence of Trichoderma harzianum strain T22 and indications of a novel exo- endo-heterodimeric chitinase activity.

Journal: BMC plant biology 20100101

Title: Income-, education- and gender-related inequalities in out-of-pocket health-care payments for 65+ patients - a systematic review.

Journal: International journal for equity in health 20100101

Title: Markers of oxidative stress in erythrocytes and plasma during aging in humans.

Journal: Oxidative medicine and cellular longevity 20100101

Title: Beta-carboline alkaloids and essential tremor: exploring the environmental determinants of one of the most prevalent neurological diseases.

Journal: TheScientificWorldJournal 20100101

Title: Brain mitochondrial dysfunction in aging, neurodegeneration, and Parkinson's disease.

Journal: Frontiers in aging neuroscience 20100101

Title: New one-pot methodologies for the modification or synthesis of alkaloid scaffolds.

Journal: Marine drugs 20100101

Title: Effects of cooking variables on formation of heterocyclic amines (HCA) in roasted pork and mackerel.

Journal: Journal of toxicology and environmental health. Part A 20100101

Title: Comparison of stainless and mild steel welding fumes in generation of reactive oxygen species.

Journal: Particle and fibre toxicology 20100101

Title: Vulnerability of mesostriatal dopaminergic neurons in Parkinson's disease.

Journal: Frontiers in neuroanatomy 20100101

Title: Evolution of allosteric citrate binding sites on 6-phosphofructo-1-kinase.

Journal: PloS one 20100101

Title: Harmine and imipramine promote antioxidant activities in prefrontal cortex and hippocampus.

Journal: Oxidative medicine and cellular longevity 20100101

Title: Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses.

Journal: PloS one 20100101

Title: Alzheimer's disease and anesthesia.

Journal: Frontiers in neuroscience 20100101

Title: Oxidative stress and longevity in okinawa: an investigation of blood lipid peroxidation and tocopherol in okinawan centenarians.

Journal: Current gerontology and geriatrics research 20100101

Title: On the need for Embodied and Dis-Embodied Cognition.

Journal: Frontiers in psychology 20100101

Title: 1-Hydroxypyrene--a biochemical marker for PAH pollution assessment of aquatic ecosystem.

Journal: Sensors (Basel, Switzerland) 20100101

Title: Activation of the immune response is a key feature of aging in mice.

Journal: Biogerontology 20091201

Title: Gene expression profile of mesenchymal stem cells from paired umbilical cord units: cord is different from blood.

Journal: Stem cell reviews 20091201

Title: Molecular, genetic and epigenetic pathways of peroxynitrite-induced cellular toxicity.

Journal: Interdisciplinary toxicology 20091201

Title: Schwannoma of the tongue: two case reports and review of the literature.

Journal: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20091101

Title: Ionizing radiation and aging: rejuvenating an old idea.

Journal: Aging 20091101

Title: Human and mouse trace amine-associated receptor 1 have distinct pharmacology towards endogenous monoamines and imidazoline receptor ligands.

Journal: The Biochemical journal 20091023

Title: Structure-activity relationship of antiparasitic and cytotoxic indoloquinoline alkaloids, and their tricyclic and bicyclic analogues.

Journal: Bioorganic & medicinal chemistry 20091015

Title: Age-related transcriptional changes in gene expression in different organs of mice support the metabolic stability theory of aging.

Journal: Biogerontology 20091001

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: 13-[4,5-Bis(methyl-sulfan-yl)-1,3-dithiol-2-yl-idene]-6-oxa-3,9,12,14-tetra-thia-bicyclo-[9.3.0]tetra-dec-1(11)-ene.

Journal: Acta crystallographica. Section E, Structure reports online 20091001

Title: Molecular determinants of beta-carboline inhibition of the glycine receptor.

Journal: Journal of neurochemistry 20090901

Title: Acetylcholinesterase inhibitive activity-guided isolation of two new alkaloids from seeds of Peganum nigellastrum Bunge by an in vitro TLC- bioautographic assay.

Journal: Archives of pharmacal research 20090901

Title: Preparation and characterisation of fried chicken as a laboratory reference material for the analysis of heterocyclic amines.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090715

Title: Identification of an imidazoline binding protein: creatine kinase and an imidazoline-2 binding site.

Journal: Brain research 20090707

Title: One- and two-photon excitation of beta-carbolines in aqueous solution: pH-dependent spectroscopy, photochemistry, and photophysics.

Journal: The journal of physical chemistry. A 20090618

Title: The effects of synthetic and endogenous imidazoline binding site ligands on neuronal activity in discrete brain regions of naive and restraint-stressed rats.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20090501

Title: Poly(ADP-ribose) polymerase 1 at the crossroad of metabolic stress and inflammation in aging.

Journal: Aging 20090501

Title: 1-(m-Chlorophenyl)piperazine induces depressogenic-like behaviour in rodents by stimulating the neuronal 5-HT(2A) receptors: proposal of a modified rodent antidepressant assay.

Journal: European journal of pharmacology 20090417

Title: 5-Bromo-8-methoxy-1-methyl-beta-carboline, an alkaloid from the New Zealand marine bryozoan Pterocella vesiculosa.

Journal: Journal of natural products 20090401

Title: Mitochondria-targeted antioxidant SkQ1 inhibits age-dependent involution of the thymus in normal and senescence-prone rats.

Journal: Aging 20090401

Title: One-electron oxidation of ruthenocene: reactions of the ruthenocenium ion in gentle electrolyte media.

Journal: Inorganic chemistry 20090302

Title: 'Getting through' not 'going under': a qualitative study of gender and spousal support after diagnosis with colorectal cancer.

Journal: Social science & medicine (1982) 20090301

Title: Oxidative stress biomarkers and lifestyles in Japanese healthy people.

Journal: Journal of clinical biochemistry and nutrition 20090301

Title: Analysis of heterocyclic amines and beta-carbolines by liquid chromatography-mass spectrometry in cooked meats commonly consumed in Korea.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20090301

Title: 3-Hydr-oxy-1,2,3,9-tetra-hydro-pyrrolo[2,1-b]quinazolin-4-ium chloride dihydrate: (+)-vasicinol hydro-chloride dihydrate from Peganum harmala L.

Journal: Acta crystallographica. Section E, Structure reports online 20090301

Title: The effect of temperature on the stability of compounds used as UV-MALDI-MS matrix: 2,5-dihydroxybenzoic acid, 2,4,6-trihydroxyacetophenone, alpha-cyano-4-hydroxycinnamic acid, 3,5-dimethoxy-4-hydroxycinnamic acid, nor-harmane and harmane.

Journal: Journal of mass spectrometry : JMS 20090201

Title: Antiplatelet activity of beta-carboline alkaloids from Perganum harmala: a possible mechanism through inhibiting PLCgamma2 phosphorylation.

Journal: Vascular pharmacology 20090101

Title: MBA: a literature mining system for extracting biomedical abbreviations.

Journal: BMC bioinformatics 20090101

Title: Is searching full text more effective than searching abstracts?

Journal: BMC bioinformatics 20090101

Title: Abdominal compartment syndrome: pathophysiology and definitions.

Journal: Scandinavian journal of trauma, resuscitation and emergency medicine 20090101

Title: The role of estrogen, testosterone, and parathyroid hormones in combination with conventional and sustained antioxidant treatment on lncap cells - biomed 2009.

Journal: Biomedical sciences instrumentation 20090101

Title: The role of causal criteria in causal inferences: Bradford Hill's 'aspects of association'.

Journal: Epidemiologic perspectives & innovations : EP+I 20090101

Title: Optimized HPLC method for analysis of polar and nonpolar heterocyclic amines in cooked meat products.

Journal: Journal of AOAC International 20090101

Title: Colony collapse disorder: a descriptive study.

Journal: PloS one 20090101

Title: European species of Hypocrea Part I. The green-spored species.

Journal: Studies in mycology 20090101

Title: Smoking induces long-lasting effects through a monoamine-oxidase epigenetic regulation.

Journal: PloS one 20090101

Title: Understanding the molecular basis of plant growth promotional effect of Pseudomonas fluorescens on rice through protein profiling.

Journal: Proteome science 20090101

Title: Detection of autoantibodies against recombinant desmoglein 1 and 3 molecules in patients with pemphigus vulgaris: correlation with disease extent at the time of diagnosis and during follow-up.

Journal: Clinical & developmental immunology 20090101

Title: Global and local perceptual style, field-independence, and central coherence: An attempt at concept validation.

Journal: Advances in cognitive psychology 20090101

Title: Oxidative stress in ageing of hair.

Journal: International journal of trichology 20090101

Title: Dietary calcium and dairy modulation of oxidative stress and mortality in aP2-agouti and wild-type mice.

Journal: Nutrients 20090101

Title: Synthesis and cytotoxic activities of 1-benzylidine substituted beta-carboline derivatives.

Journal: Bioorganic & medicinal chemistry letters 20081215

Title: Quantification of heterocyclic amines from thermally processed meats selected from a small-scale population-based study.

Journal: Molecular nutrition & food research 20081201

Title: 3D and quantum QSAR of non-benzodiazepine compounds.

Journal: European journal of medicinal chemistry 20081101

Title: Effect of Peganum harmala or its beta-carboline alkaloids on certain antibiotic resistant strains of bacteria and protozoa from poultry.

Journal: Phytotherapy research : PTR 20081101

Title: Oxidative metabolism of the bioactive and naturally occurring beta-carboline alkaloids, norharman and harman, by human cytochrome P450 enzymes.

Journal: Chemical research in toxicology 20081101

Title: (Benzophenone imine-κN)-chlorido(hydrido-tripyrazolyl-borato)-(triphenyl-phosphine)ruthenium(II) diethyl ether solvate.

Journal: Acta crystallographica. Section E, Structure reports online 20081101

Title: Environmental epidemiology of essential tremor.

Journal: Neuroepidemiology 20081001

Title: Molecular basis of halorespiration control by CprK, a CRP-FNR type transcriptional regulator.

Journal: Molecular microbiology 20081001

Title: Cancer and blood concentrations of the comutagen harmane in essential tremor.

Journal: Movement disorders : official journal of the Movement Disorder Society 20080915

Title: The functional anatomy of semantic retrieval is influenced by gender, menstrual cycle, and sex hormones.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20080901

Title: Deletion of cd39/entpd1 results in hepatic insulin resistance.

Journal: Diabetes 20080901

Title: Staff behaviour and resident engagement before and after active support training.

Journal: Journal of intellectual & developmental disability 20080901

Title: Active support is person-centred by definition: a response to Harman and Sanderson (2008).

Journal: Journal of intellectual & developmental disability 20080901

Title: [Studies on alkalodial constituents in leaves of Uncaria hirsuta].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080901

Title: The use of natural product scaffolds as leads in the search for trypanothione reductase inhibitors.

Journal: Bioorganic & medicinal chemistry 20080715

Title: Quantitative structure-activity relationship studies of a series of non-benzodiazepine structural ligands binding to benzodiazepine receptor.

Journal: European journal of medicinal chemistry 20080701

Title: The desmosome and pemphigus.

Journal: Histochemistry and cell biology 20080701

Title: Evaluation of peak power prediction equations in male basketball players.

Journal: Journal of strength and conditioning research 20080701

Title: Quantification of heterocyclic aromatic amines in fried meat by HPTLC/UV-FLD and HPLC/UV-FLD: a comparison of two methods.

Journal: Journal of agricultural and food chemistry 20080625

Title: Effects of harman and norharman on dopamine biosynthesis and L-DOPA-induced cytotoxicity in PC12 cells.

Journal: European journal of pharmacology 20080610

Title: Indolealkylamines: biotransformations and potential drug-drug interactions.

Journal: The AAPS journal 20080601

Title: Influence of the presence of methyl cyclodextrins in high-performance liquid chromatography mobile phases on the separation of beta-carboline alkaloids.

Journal: Journal of chromatography. A 20080530

Title: Dietary epidemiology of essential tremor: meat consumption and meat cooking practices.

Journal: Neuroepidemiology 20080501

Title: Higher blood harmane (1-methyl-9H-pyrido[3,4-b]indole) concentrations correlate with lower olfactory scores in essential tremor.

Journal: Neurotoxicology 20080501

Title: The mitochondrial free radical theory of ageing--where do we stand?

Journal: Frontiers in bioscience : a journal and virtual library 20080501

Title: Ethylene-induced modulation of genes associated with the ethylene signalling pathway in ripening kiwifruit.

Journal: Journal of experimental botany 20080501

Title: Lysosomes in iron metabolism, ageing and apoptosis.

Journal: Histochemistry and cell biology 20080401

Title: Elevated blood harmane (1-methyl-9H-pyrido[3,4-b]indole) concentrations in essential tremor.

Journal: Neurotoxicology 20080301

Title: The endogenous alkaloid harmane: acidifying and activity-reducing effects on hippocampal neurons in vitro.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20080215

Title: What parathyroid hormone levels should we aim for in children with stage 5 chronic kidney disease; what is the evidence?

Journal: Pediatric nephrology (Berlin, Germany) 20080201

Title: Does ligament balancing technique affect kinematics in rotating platform, PCL retaining knee arthroplasties? A prospective randomized study.

Journal: Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA 20080201

Title: Purifying selection and birth-and-death evolution in the class II hydrophobin gene families of the ascomycete Trichoderma/Hypocrea.

Journal: BMC evolutionary biology 20080101

Title: Determination of beta-carboline alkaloids in fruiting bodies of Hygrophorus spp. by liquid chromatography/electrospray ionisation tandem mass spectrometry.

Journal: Phytochemical analysis : PCA 20080101

Title: Graphical presentation of diagnostic information.

Journal: BMC medical research methodology 20080101

Title: PageRank without hyperlinks: reranking with PubMed related article networks for biomedical text retrieval.

Journal: BMC bioinformatics 20080101

Title: Chemical markers for the quality control of herbal medicines: an overview.

Journal: Chinese medicine 20080101

Title: The information highways of a biotechnological workhorse--signal transduction in Hypocrea jecorina.

Journal: BMC genomics 20080101

Title: Retrieved Unicompartmental Implants with Full PE Tibial Components: The Effects of Knee Alignment and Polyethylene Thickness on Creep and Wear.

Journal: The open orthopaedics journal 20080101

Title: The selectivity of protein kinase inhibitors: a further update.

Journal: The Biochemical journal 20071215

Title: Degradation of heterocyclic aromatic amines in oil under storage and frying conditions and reduction of their mutagenic potential.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20071101

Title: Elevated blood lead concentrations in essential tremor: a case-control study in Mersin, Turkey.

Journal: Environmental health perspectives 20071101

Title: Identification and occurrence of beta-carboline alkaloids in raisins and inhibition of monoamine oxidase (MAO).

Journal: Journal of agricultural and food chemistry 20071017

Title: Role of acetaldehyde in tobacco smoke addiction.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20071001

Title: Coupled hydrogen-bonding interactions between beta-carboline derivatives and acetic acid.

Journal: Magnetic resonance in chemistry : MRC 20071001

Title: [Graphical modeling for constructs: an integrated solution for factor analysis and GM].

Journal: Shinrigaku kenkyu : The Japanese journal of psychology 20071001

Title: Synthesis of 3,8,9-trisubstituted-1,7,9-triaza-fluorene-6-carboxylic acid derivatives as a new class of insulin secretagogues.

Journal: Bioorganic & medicinal chemistry 20070901

Title: The aging process and potential interventions to extend life expectancy.

Journal: Clinical interventions in aging 20070901

Title: Trends in oxidative aging theories.

Journal: Free radical biology & medicine 20070815

Title: Blood harmane is correlated with cerebellar metabolism in essential tremor: a pilot study.

Journal: Neurology 20070807

Title: Validation of an ion-pair liquid chromatography-electrospray-tandem mass spectrometry method for the determination of heterocyclic aromatic amines in meat-based infant foods.

Journal: Food additives and contaminants 20070801

Title: Antioxidant properties of beta-carboline alkaloids are related to their antimutagenic and antigenotoxic activities.

Journal: Mutagenesis 20070701

Title: Quantification of the neurotoxic beta-carboline harmane in barbecued/grilled meat samples and correlation with level of doneness.

Journal: Journal of toxicology and environmental health. Part A 20070601

Title: Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence.

Journal: PLoS biology 20070501

Title: Biomechanics of the anterior cruciate ligament and implications for surgical reconstruction.

Journal: Strategies in trauma and limb reconstruction (Online) 20070401

Title: Factors influencing the norharman and harman contents in espresso coffee.

Journal: Journal of agricultural and food chemistry 20070307

Title: Determination of beta-carboline alkaloids in foods and beverages by high-performance liquid chromatography with electrochemical detection at a glassy carbon electrode modified with carbon nanotubes.

Journal: Analytica chimica acta 20070307

Title: Validation of a new planar chromatographic method for quantification of the heterocyclic aromatic amines most frequently found in meat.

Journal: Analytical and bioanalytical chemistry 20070201

Title: Protection from oxidative stress by enhanced glycolysis; a possible mechanism of cellular immortalization.

Journal: Histology and histopathology 20070101

Title: Do longer consultations improve the management of psychological problems in general practice? A systematic literature review.

Journal: BMC health services research 20070101

Title: Faster rates of post-puberty kidney deterioration in males is correlated with elevated oxidative stress in males vs females at early puberty.

Journal: BMC genomics 20070101

Title: Structural characterization of native high-methoxylated pectin using nuclear magnetic resonance spectroscopy and ultraviolet matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Comparative use of 2,5-dihydroxybenzoic acid and nor-harmane as UV-MALDI matrices.

Journal: Rapid communications in mass spectrometry : RCM 20070101

Title: PubMed related articles: a probabilistic topic-based model for content similarity.

Journal: BMC bioinformatics 20070101

Title: Significant and systematic expression differentiation in long-lived yeast strains.

Journal: PloS one 20070101

Title: Mediterranean diet and essential tremor. A case-control study.

Journal: Neuroepidemiology 20070101

Title: Heart valve tissue engineering: concepts, approaches, progress, and challenges.

Journal: Annals of biomedical engineering 20061201

Title: Mental health and substance abuse services preferences among American Indian people of the northern Midwest.

Journal: Community mental health journal 20061201

Title: Comparative aromatic hydroxylation and N-demethylation of MPTP neurotoxin and its analogs, N-methylated beta-carboline and isoquinoline alkaloids, by human cytochrome P450 2D6.

Journal: Toxicology and applied pharmacology 20061101

Title: Activation of aminophenylnorharman, aminomethylphenylnorharman and aminophenylharman to genotoxic metabolites by human N-acetyltransferases and cytochrome P450 enzymes expressed in Salmonella typhimurium umu tester strains.

Journal: Mutagenesis 20061101

Title: Effect of red wine marinades on the formation of heterocyclic amines in fried chicken breast.

Journal: Journal of agricultural and food chemistry 20061018

Title: Efficacy of planar chromatography coupled to (tandem) mass spectrometry for employment in trace analysis.

Journal: Journal of chromatography. A 20060922

Title: Neurochemical mechanisms of the dorsal pallidum in the antiaversive effects of anxiolytics in various models of anxiety.

Journal: Neuroscience and behavioral physiology 20060901

Title: Partial least squares-based multivariate spectral calibration method for simultaneous determination of beta-carboline derivatives in Peganum harmala seed extracts.

Journal: Analytica chimica acta 20060811

Title: Monoamine oxidase inhibitors allow locomotor and rewarding responses to nicotine.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060801

Title: Analysis of monoamine oxidase enzymatic activity by reversed-phase high performance liquid chromatography and inhibition by beta-carboline alkaloids occurring in foods and plants.

Journal: Journal of chromatography. A 20060707

Title: Antidepressant-like effect of harmane and other beta-carbolines in the mouse forced swim test.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20060701

Title: Phytochemical and pharmacological study of roots and leaves of Guiera senegalensis J.F. Gmel (Combretaceae).

Journal: Journal of ethnopharmacology 20060630

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Tissue-specific deletion patterns of the mitochondrial genome with advancing age.

Journal: Experimental gerontology 20060501

Title: Theoretical study of structure, pKa, lipophilicity, solubility, absorption, and polar surface area of some centrally acting antihypertensives.

Journal: Bioorganic & medicinal chemistry 20060315

Title: In vitro and ex vivo distribution of [3H]harmane, an endogenous beta-carboline, in rat brain.

Journal: Neuropharmacology 20060301

Title: Autoradiographical distribution of imidazoline binding sites in monoamine oxidase A deficient mice.

Journal: Journal of neurochemistry 20060301

Title: [Ageing free radicals and cellular stress].

Journal: Medecine sciences : M/S 20060301

Title: Effect of chlorine as substituent on the photochemistry and acid-base properties of beta-carboline alkaloids.

Journal: Journal of photochemistry and photobiology. B, Biology 20060201

Title: Human monoamine oxidase enzyme inhibition by coffee and beta-carbolines norharman and harman isolated from coffee.

Journal: Life sciences 20060118

Title: Understanding the importance of selenium and selenoproteins in muscle function.

Journal: Cellular and molecular life sciences : CMLS 20060101

Title: Imidazoline receptors, novel agents and therapeutic potential.

Journal: Cardiovascular & hematological agents in medicinal chemistry 20060101

Title: Melatonin in Alzheimer's disease and other neurodegenerative disorders.

Journal: Behavioral and brain functions : BBF 20060101

Title: Apoptosis and aging: role of p66Shc redox protein.

Journal: Antioxidants & redox signaling 20060101

Title: Enhancing access to the Bibliome: the TREC 2004 Genomics Track.

Journal: Journal of biomedical discovery and collaboration 20060101

Title: Centrally acting imidazolines stimulate vascular alpha 1A-adrenergic receptors in Rat-Tail Artery.

Journal: Cellular and molecular neurobiology 20060101

Title: The Trichoderma koningii aggregate species.

Journal: Studies in mycology 20060101

Title: Harmane inhibits serotonergic dorsal raphe neurons in the rat.

Journal: Psychopharmacology 20051101

Title: Investigation of the separation of heterocyclic aromatic amines by reversed phase ion-pair liquid chromatography coupled with tandem mass spectrometry: the role of ion pair reagents on LC-MS/MS sensitivity.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051025

Title: Characterisation of imidazoline I2 binding sites in pig brain.

Journal: European journal of pharmacology 20050905

Title: Aging and gene expression in the primate brain.

Journal: PLoS biology 20050901

Title: Blood harmane concentrations and dietary protein consumption in essential tremor.

Journal: Neurology 20050809

Title: Photochemistry of the alkaloids eudistomin N (6-bromo-nor-harmane) and eudistomin O (8-bromo-nor-harmane) and other bromo-beta-carbolines.

Journal: Journal of photochemistry and photobiology. B, Biology 20050701

Title: Chronological and physiological ageing in a polar and a temperate mud clam.

Journal: Mechanisms of ageing and development 20050501

Title: Mitochondrial ageing of a polar and a temperate mud clam.

Journal: Mechanisms of ageing and development 20050501

Title: Comparison of the Protective Effect of Indole beta-carbolines and R-(-)-deprenyl Against Nitrogen Species-Induced Cell Death in Experimental Culture Model of Parkinson's Disease.

Journal: Journal of clinical neurology (Seoul, Korea) 20050401

Title: Lack of combination hepatocarcinogenicity of harman, norharman and amitrole when given with NaNO2 in the rat.

Journal: The Journal of toxicological sciences 20050201

Title: Human monoamine oxidase is inhibited by tobacco smoke: beta-carboline alkaloids act as potent and reversible inhibitors.

Journal: Biochemical and biophysical research communications 20050114

Title: Beta-carbolines induce apoptosis in cultured cerebellar granule neurons via the mitochondrial pathway.

Journal: Neuropharmacology 20050101

Title: Modulation of voltage-gated channel currents by harmaline and harmane.

Journal: British journal of pharmacology 20050101

Title: Matrix-assisted ultraviolet laser desorption/ionization time-of-flight mass spectrometry of beta-(1 --> 3), beta-(1 --> 4)-xylans from Nothogenia fastigiata using nor-harmane as matrix.

Journal: Rapid communications in mass spectrometry : RCM 20050101

Title: Estimate of illnesses from Salmonella enteritidis in eggs, United States, 2000.

Journal: Emerging infectious diseases 20050101

Title: Fluorescence quenching of beta-carboline alkaloids in micellar media. A study to select the adequate surfactant to use in analytical techniques.

Journal: Luminescence : the journal of biological and chemical luminescence 20050101

Title: Comprehensive photochemistry and photophysics of land- and marine-based beta-carbolines employing time-resolved emission and flash transient spectroscopy.

Journal: Photochemistry and photobiology 20050101

Title: Melatonin, immune function and aging.

Journal: Immunity & ageing : I & A 20050101

Title: Harmane and harmalan are bioactive components of classical clonidine-displacing substance.

Journal: Biochemistry 20041228

Title: Relative exposure to beta-carbolines norharman and harman from foods and tobacco smoke.

Journal: Food additives and contaminants 20041101

Title: The putative imidazoline receptor agonist, harmane, promotes intracellular calcium mobilisation in pancreatic beta-cells.

Journal: European journal of pharmacology 20041006

Title: Evaluation of power prediction equations: peak vertical jumping power in women.

Journal: Medicine and science in sports and exercise 20040901

Title: Analysis of alpha- and beta-carbolines in mainstream smoke of reference cigarettes by gas chromatography-mass spectrometry.

Journal: Journal of chromatography. A 20040813

Title: He's the dean of CEOs. Harman has held the top job at his West Virginia hospital for nearly 40 years--and counting.

Journal: Modern healthcare 20040802

Title: Modulation of cytochrome P450 1A1 by food-derived heterocyclic aromatic amines.

Journal: Toxicology 20040701

Title: Uncoupled and surviving: individual mice with high metabolism have greater mitochondrial uncoupling and live longer.

Journal: Aging cell 20040601

Title: Use of horseradish peroxidase for gene-directed enzyme prodrug therapy with paracetamol.

Journal: British journal of cancer 20040504

Title: Transport of harman alkaloids across Caco-2 cell monolayers.

Journal: Chemical & pharmaceutical bulletin 20040401

Title: High-performance liquid chromatographic analysis of beta-carbolines in human scalp hair.

Journal: Journal of chromatography. A 20040326

Title: Occurrence of heterocyclic amines in several home-cooked meat dishes of the Spanish diet.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040325

Title: Exposure to beta-carbolines norharman and harman.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040325

Title: Mutagens formed from beta-carbolines with aromatic amines.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040325

Title: Dermatology in Nigeria: evolution, establishment and current status.

Journal: International journal of dermatology 20040301

Title: The effects of imidazoline agents on the aggregation of human platelets.

Journal: The Journal of pharmacy and pharmacology 20040201

Title: Leading by feel.

Journal: Harvard business review 20040101

Title: A pauper dead-house: the expansion of the Cambridge anatomical teaching school under the late-Victorian poor law, 1870-1914.

Journal: Medical history 20040101

Title: In vitro activity of the beta-carboline alkaloids harmane, harmine, and harmaline toward parasites of the species Leishmania infantum.

Journal: Experimental parasitology 20040101

Title: Effects of the beta-carbolines, harmane and pinoline, on insulin secretion from isolated human islets of Langerhans.

Journal: European journal of pharmacology 20031215

Title: Endogenous beta-carbolines as clonidine-displacing substances.

Journal: Annals of the New York Academy of Sciences 20031201

Title: Comparative effects of efaroxan and beta-carbolines on the secretory activity of rodent and human beta cells.

Journal: Annals of the New York Academy of Sciences 20031201

Title: Characterization of [(3)H]harmane binding to rat whole brain membranes.

Journal: Annals of the New York Academy of Sciences 20031201

Title: Effect of harmane on mononeuropathic pain in rats.

Journal: Annals of the New York Academy of Sciences 20031201

Title: Inhibitory effect of harmane on morphine-dependent Guinea pig ileum.

Journal: Annals of the New York Academy of Sciences 20031201

Title: Effect of harmane on the convulsive threshold in epilepsy models in mice.

Journal: Annals of the New York Academy of Sciences 20031201

Title: Harmane induces anxiolysis and antidepressant-like effects in rats.

Journal: Annals of the New York Academy of Sciences 20031201

Title: Endogenous imidazoline receptor ligands relax rat aorta by an endothelium-dependent mechanism.

Journal: Annals of the New York Academy of Sciences 20031201

Title: Atypical [(3)H]clonidine binding sites in human caudate and platelets on cryostat-cut sections.

Journal: Annals of the New York Academy of Sciences 20031201

Title: Influence of antioxidants in virgin olive oil on the formation of heterocyclic amines in fried beefburgers.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20031101

Title: Effects of harman and harmine on naloxone-precipitated withdrawal syndrome in morphine-dependent rats.

Journal: Life sciences 20030919

Title: Detection and characterization of cyclodextrin complexes with beta-carboline derivatives by spectroscopic techniques.

Journal: Journal of pharmaceutical and biomedical analysis 20030808

Title: Microbial metabolites of harman alkaloids.

Journal: Chemical & pharmaceutical bulletin 20030601

Title: Agmatine and imidazoline systems--fourth international symposium: 9-11 April 2003, San Diego, CA, USA.

Journal: IDrugs : the investigational drugs journal 20030601

Title: Identification of harman as the antibiotic compound produced by a tunicate-associated bacterium.

Journal: Marine biotechnology (New York, N.Y.) 20030101

Title: Oxidative stress and aging.

Journal: Advances in experimental medicine and biology 20030101

Title: Elevation of blood beta-carboline alkaloids in essential tremor.

Journal: Neurology 20021224

Title: Antimalarial activity of extracts and alkaloids isolated from six plants used in traditional medicine in Mali and Sao Tome.

Journal: Phytotherapy research : PTR 20021101

Title: Collision-induced dissociation actualized the H+-promoted reaction as observed in vitro; harman formation from beta-carboline-type monoterpenoid glucoindole alkaloids.

Journal: Chemical & pharmaceutical bulletin 20021101

Title: Jump evaluation of elite volleyball players using two methods: jump power equations and force platform.

Journal: The Journal of sports medicine and physical fitness 20020901

Title: Dynamic study of excited state hydrogen-bonded complexes of harmane in cyclohexane-toluene mixtures.

Journal: Photochemistry and photobiology 20020901

Title: Screening for heterocyclic amines in chicken cooked in various ways.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20020801

Title: Multistep mass spectrometry of heterocyclic amines in a quadrupole ion trap mass analyser.

Journal: Journal of mass spectrometry : JMS 20020801

Title: Identification and occurrence of the bioactive beta-carbolines norharman and harman in coffee brews.

Journal: Food additives and contaminants 20020801

Title: Tetrahydro-beta-carboline alkaloids that occur in foods and biological systems act as radical scavengers and antioxidants in the ABTS assay.

Journal: Free radical research 20020801

Title: Phenylethanolamine N-methyltransferase has beta-carboline 2N-methyltransferase activity: hypothetical relevance to Parkinson's disease.

Journal: Neurochemistry international 20020601

Title: Affinitive separation and on-line identification of antitumor components from Peganum nigellastrum by coupling a chromatographic column of target analogue imprinted polymer with mass spectrometry.

Journal: Analytical chemistry 20020515

Title: Natural variations of precursors in pig meat affect the yield of heterocyclic amines--effects of RN genotype, feeding regime, and sex.

Journal: Journal of agricultural and food chemistry 20020508

Title: 5-HT2A receptor-stimulated phosphoinositide hydrolysis in the stimulus effects of hallucinogens.

Journal: Pharmacology, biochemistry, and behavior 20020501

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: The levels of norharman are high enough after smoking to affect monoamineoxidase B in platelets.

Journal: European journal of pharmacology 20020419

Title: Beta-carbolines as specific inhibitors of cyclin-dependent kinases.

Journal: Bioorganic & medicinal chemistry letters 20020408

Title: Pro-oxidant and anti-oxidant mechanism(s) of BHT and beta-carotene in photocarcinogenesis.

Journal: Frontiers in bioscience : a journal and virtual library 20020401

Title: Induction of sister chromatid exchanges and chromosome aberrations in cultured mammalian cells treated with aminophenylnorharman formed by norharman with aniline.

Journal: Mutation research 20020325

Title: Genotoxic and recombinogenic activities of the two beta-carboline alkaloids harman and harmine in Saccharomyces cerevisiae.

Journal: Mutation research 20020320

Title: Synergistic in vitro antimalarial activity of plant extracts used as traditional herbal remedies in Mali.

Journal: Parasitology research 20020201

Title: Free radicals in the physiological control of cell function.

Journal: Physiological reviews 20020101

Title: An in vitro evaluation of human DNA topoisomerase I inhibition by Peganum harmala L. seeds extract and its beta-carboline alkaloids.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20020101

Title: [Serum norharman and harman analysis using high pressure liquid chromatography/mass spectrometry and value of beta-carbolines as blood alcohol markers].

Journal: Archiv fur Kriminologie 20020101

Title: Toxicokinetics of tremorogenic natural products, harmane and harmine, in male Sprague-Dawley rats.

Journal: Journal of toxicology and environmental health. Part A 20011221

Title: Degradation of tetrahydro-beta-carbolines in the presence of nitrite: HPLC-MS analysis of the reaction products.

Journal: Journal of agricultural and food chemistry 20011201

Title: Genotoxic effects of the alkaloids harman and harmine assessed by comet assay and chromosome aberration test in mammalian cells in vitro.

Journal: Pharmacology & toxicology 20011201

Title: Spasmolytic effects of three harmala alkaloids on guinea-pig isolated trachea.

Journal: Pharmacology & toxicology 20011101

Title: Amino acid substitution at position 99 affects the rate of CRP subunit exchange.

Journal: Biochemistry 20011016

Title: [Neurochemical characteristics of the ventromedial hypothalamus and anti-aversive effects of anxiolytic agents in various anxiety models].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20010901

Title: Stimulatory effect of harmane and other beta-carbolines on locus coeruleus neurons in anaesthetized rats.

Journal: Neuroscience letters 20010810

Title: Anti-AIDS agents. 46. Anti-HIV activity of harman, an anti-HIV principle from Symplocos setchuensis, and its derivatives.

Journal: Journal of natural products 20010701

Title: Manipulating and recognizing virtual objects: where the action is.

Journal: Canadian journal of experimental psychology = Revue canadienne de psychologie experimentale 20010601

Title: Identification of co-mutagenic chlorinated harmans in final effluent from a sewage treatment plant.

Journal: Mutation research 20010405

Title: Hydrogen bonding NH/pi interactions between betacarboline and methyl benzene derivatives.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20010401

Title: Do antioxidant strategies work against aging and age-associated disorders? Propargylamines: a possible antioxidant strategy.

Journal: Annals of the New York Academy of Sciences 20010401

Title: Neural substrates of mathematical reasoning: a functional magnetic resonance imaging study of neocortical activation during performance of the necessary arithmetic operations test.

Journal: Neuropsychology 20010101

Title: Garbage catastrophe theory of aging: imperfect removal of oxidative damage?

Journal: Redox report : communications in free radical research 20010101

Title: Norharman, an indoleamine-derived beta-carboline, but not Trp-P-2, a gamma-carboline, induces apoptotic cell death in human neuroblastoma SH-SY5Y cells.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20010101

Title: Evaluation of pyridoindoles, pyridylindoles and pyridylpyridoindoles as matrices for ultraviolet matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20010101

Title: Effects of beta- and gamma-carboline derivatives of DNA topoisomerase activities.

Journal: Mutation research 19960201

Title: Development of a pharmacophore for inhibition of human liver cytochrome P-450 2D6: molecular modeling and inhibition studies.

Journal: Journal of medicinal chemistry 19930430

Title: Anticonvulsant effects of caerulein, cholecystokinin octapeptide (CCK-8) and diazepam against seizures produced in mice by harman, thiosemicarbazide and isoniazid.

Journal: Neuroscience letters 19810702

Title: Louis ED, et, al. Blood harmane concentrations and dietary protein consumption in essential tremor. Neurology. 2005 Aug 9;65(3):391-6.

Title: Musgrave IF, et, al. Harmane produces hypotension following microinjection into the RVLM: possible role of I(1)-imidazoline receptors. Br J Pharmacol. 2000 Mar;129(6):1057-9.

Title: Glover V, et, al. β-Carbolines as selective monoamine oxidase inhibitors:In vivo implications

Title: Umezawa K, et, al. Comutagenic effect of norharman and harman with 2-acetylaminofluorene derivatives. Proc Natl Acad Sci U S A. 1978 Feb;75(2):928-30.

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Tags:486-84-0 Molecular Formula|486-84-0 MDL|486-84-0 SMILES|486-84-0 Harmane |Heterocyclic_Building_Blocks