Name: Name:1-[(3-Bromobenzene)sulfonyl]-4-methylpiperazine
Brand: AABLOCKS
SKU: AA00DC32
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00DC32

Chemical Name: 1-[(3-Bromobenzene)sulfonyl]-4-methylpiperazine

CAS Number: 486422-19-9

Molecular Formula: C11H15BrN2O2S

Molecular Weight: 319.2180

MDL Number: MFCD10000772

SMILES: CN1CCN(CC1)S(=O)(=O)c1cccc(c1)Br

Properties

Complexity: 347

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 17

Hydrogen Bond Acceptor Count: 4

Hydrogen Bond Donor Count: 0

Isotope Atom Count: 0

Rotatable Bond Count: 2

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 1.6

Downstream Synthesis Route

867333-35-5

486422-19-9

7-(2,6-dimethyl-phenyl)-5-methyl-benzo1,2,4triazin-3-yl-3-(4-methyl-piperazine-1-sulfonyl)-phenyl-amine

[1]Noronha,Glenn;Barrett,Kathy;Cao,Jianguo;Dneprovskaia,Elena;Fine,Richard;Gong,Xianchang;Gritzen,Colleen;Hood,John;Kang,Xinshan;Klebansky,Boris;Li;Liao;Lohse,Dan;Mak,ChiChing;McPherson,Andrew;Palanki,MoorthyS.S.;Pathak,VedP.;Renick,Joel;Soll,Richard;Splittgerber,Ute;Wrasidlo,Wolfgang;Zeng,Binqi;Zhao,Ningning;Zhou[BioorganicandMedicinalChemistryLetters,2006,vol.16,#21,p.5546-5550]

109-01-3

2905-24-0

486422-19-9

[1]CurrentPatentAssignee:SANOFI-US2005/245524,2005,A1Locationinpatent:Page/Pagecolumn40

[2]CurrentPatentAssignee:ANTABIOSAS-EP3628672,2020,A1Locationinpatent:Paragraph0457-0459

[3]CurrentPatentAssignee:Novartis(w/oSandoz);NOVARTISAG-US2009/239847,2009,A1Locationinpatent:Page/Pagecolumn43

[4]Locationinpatent:schemeortableShim,Jaechul;Eid,Clark;Lee,Julie;Liu,Erica;Chaudhary,Divya;Boschelli,DianeH.[BioorganicandMedicinalChemistryLetters,2009,vol.19,#23,p.6575-6577]

[5]Berg,Stefan;Bergh,Margareta;Hellberg,Sven;Hoegdin,Katharina;Lo-Alfredsson,Yvonne;Soederman,Peter;VonBerg,Stefan;Weigelt,Tatjana;Ormoe,Mats;Xue,Yafeng;Tucker,Julie;Neelissen,Jan;Jerning,Eva;Nilsson,Yvonne;Bhat,Ratan[JournalofMedicinalChemistry,2012,vol.55,#21,p.9107-9119,13]

867330-72-1

486422-19-9

7-(2-chloro-5-methoxy-phenyl)-5-methyl-benzo1,2,4triazin-3-yl-3-(4-methyl-piperazine-1-sulfonyl)-phenyl-amine

[1]CurrentPatentAssignee:SANOFI-US2005/245524,2005,A1Locationinpatent:Page/Pagecolumn40-41

486422-19-9

C17H20BN3O3

1188409-60-0

[1]CurrentPatentAssignee:Novartis(w/oSandoz);NOVARTISAG-US2009/239847,2009,A1Locationinpatent:Page/Pagecolumn33-34