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Home Other Building Blocks 488-04-0
488-04-0,MFCD01670588
Catalog No.:AA00DXFP

488-04-0 | holomycin

Pack Size
Purity
Availability
Price(USD)
Quantity
  
2.5mg
3 weeks  
$580.00   $406.00
- +
25mg
3 weeks  
$3,410.00   $2,387.00
- +
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00DXFP
Chemical Name:
holomycin
CAS Number:
488-04-0
Molecular Formula:
C7H6N2O2S2
Molecular Weight:
214.2647
MDL Number:
MFCD01670588
SMILES:
CC(=O)Nc1c2sscc2[nH]c1=O
Properties
Computed Properties
 
Complexity:
360  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
-0.8  

Literature

Title: Exploiting adaptive laboratory evolution of Streptomyces clavuligerus for antibiotic discovery and overproduction.

Journal: PloS one 20120101

Title: Streptomyces clavuligerus HlmI is an intramolecular disulfide-forming dithiol oxidase in holomycin biosynthesis.

Journal: Biochemistry 20110531

Title: A rhodanese-like protein is highly overrepresented in the mutant S. clavuligerus oppA2::aph: effect on holomycin and other secondary metabolites production.

Journal: Microbial biotechnology 20110301

Title: A natural plasmid uniquely encodes two biosynthetic pathways creating a potent anti-MRSA antibiotic.

Journal: PloS one 20110101

Title: Antibacterial compounds from marine Vibrionaceae isolated on a global expedition.

Journal: Marine drugs 20100101

Title: Intergeneric conjugation in holomycin-producing marine Streptomyces sp. strain M095.

Journal: Microbiological research 20080101

Title: Expedient total synthesis of pyrrothine natural products and analogs.

Journal: Organic & biomolecular chemistry 20070121

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SDS
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