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5058-13-9,MFCD07781426
Catalog No.:AA00DA25

5058-13-9 | Columbianadin

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1mg
≥98%
in stock  
$48.00   $33.00
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5mg
98%(HPLC)powder
in stock  
$120.00   $84.00
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10mg
98%(HPLC)powder
in stock  
$178.00   $125.00
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25mg
>98.0%(HPLC)
in stock  
$203.00   $142.00
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1000mg
98% by HPLC
in stock  
$6,710.00   $4,697.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00DA25
Chemical Name:
Columbianadin
CAS Number:
5058-13-9
Molecular Formula:
C19H20O5
Molecular Weight:
328.3591
MDL Number:
MFCD07781426
SMILES:
C/C=C(\C(=O)OC([C@H]1Oc2c(C1)c1oc(=O)ccc1cc2)(C)C)/C
Properties
Computed Properties
 
Complexity:
589  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
5  
Rotatable Bond Count:
4  
XLogP3:
3.7  

Literature

Title: Biotransformation of columbianadin by rat hepatic microsomes and inhibition of biotransformation products on NO production in RAW 264.7 cells in vitro.

Journal: Phytochemistry 20120901

Title: A simple RP-HPLC method for quantification of columbianadin in rat plasma and its application to pharmacokinetic study.

Journal: Biomedical chromatography : BMC 20100401

Title: [Absorption and transport of 6 coumarins isolated from the roots of Angelica pubescens f. biserrata in human Caco-2 cell monolayer model].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20080401

Title: [In situ rats single pass perfusion intestinal absorption of the effectivein components in Radix Angelicae Pubescentis].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20080101

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: [Studies on chemical constituents from the herb of Peucedanum decursivum (Miq.) Maxim].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20010301

Title: Suksdorfin: an anti-HIV principle from Lomatium suksdorfii, its structure-activity correlation with related coumarins, and synergistic effects with anti-AIDS nucleosides.

Journal: Bioorganic & medicinal chemistry 19941001

Title: Kang JI, et al. Columbianadin Inhibits Cell Proliferation by Inducing Apoptosis and Necroptosis in HCT116 Colon Cancer Cells. Biomol Ther (Seoul). 2016 May 1;24(3):320-7.

Title: Zhang YB, et al. Tissue distribution study of columbianadin and its active metabolite columbianetin in rats. Biomed Chromatogr. 2016 Feb;30(2):256-62.

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Tags:5058-13-9 Molecular Formula|5058-13-9 MDL|5058-13-9 SMILES|5058-13-9 Columbianadin