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511-09-1,MFCD26143009
Catalog No.:AA00DBJB

511-09-1 | ALPHA-ERGOCRYPTINE

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  • Properties
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00DBJB
Chemical Name:
ALPHA-ERGOCRYPTINE
CAS Number:
511-09-1
Molecular Formula:
C32H41N5O5
Molecular Weight:
575.6984
MDL Number:
MFCD26143009
SMILES:
CC(CC1C(=O)N2CCCC2C2(N1C(=O)C(O2)(NC(=O)C1CN(C)C2C(=C1)c1cccc3c1c(C2)c[nH]3)C(C)C)O)C
Properties
Computed Properties
 
Complexity:
1190  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
6  
Heavy Atom Count:
42  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
5  
XLogP3:
2.7  

Literature

Title: Constriction of bovine vasculature caused by endophyte-infected tall fescue seed extract is similar to pure ergovaline.

Journal: Journal of animal science 20120501

Title: Deoxynivalenol, deoxynivalenol-3-glucoside, and enniatins: the major mycotoxins found in cereal-based products on the Czech market.

Journal: Journal of agricultural and food chemistry 20111228

Title: Effect of ergot alkaloids on contractility of bovine right ruminal artery and vein.

Journal: Journal of animal science 20110901

Title: Cytotoxicity and accumulation of ergot alkaloids in human primary cells.

Journal: Toxicology 20110411

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: The history of ergot of rye (Claviceps purpurea) III: 1940-80.

Journal: The journal of the Royal College of Physicians of Edinburgh 20100301

Title: Contractile response of fescue-naive bovine lateral saphenous veins to increasing concentrations of tall fescue alkaloids.

Journal: Journal of animal science 20100101

Title: Development of a cell-based high-throughput assay to screen for inhibitors of organic anion transporting polypeptides 1B1 and 1B3.

Journal: Current chemical genomics 20100101

Title: Toxicity of endophyte-infected tall fescue alkaloids and grass metabolites on Pratylenchus scribneri.

Journal: Phytopathology 20091201

Title: Development and validation of an LC-MS method for quantitation of ergot alkaloids in lateral saphenous vein tissue.

Journal: Journal of agricultural and food chemistry 20090826

Title: Chemotaxis disruption in Pratylenchus scribneri by tall fescue root extracts and alkaloids.

Journal: Journal of chemical ecology 20090701

Title: Prolactin signaling through the short isoform of the mouse prolactin receptor regulates DNA binding of specific transcription factors, often with opposite effects in different reproductive issues.

Journal: Reproductive biology and endocrinology : RB&E 20090101

Title: An attempt at conservative treatment in selected cases of type I endometrial carcinoma (stage I a/G1) in young women.

Journal: European journal of gynaecological oncology 20090101

Title: Recognition properties and competitive assays of a dual dopamine/serotonin selective molecularly imprinted polymer.

Journal: International journal of molecular sciences 20081201

Title: Claviceps nigricans and Claviceps grohii: their alkaloids and phylogenetic placement.

Journal: Journal of natural products 20080601

Title: Simultaneous determination of six major ergot alkaloids and their epimers in cereals and foodstuffs by LC-MS-MS.

Journal: Analytical and bioanalytical chemistry 20080501

Title: LC-MS/MS multi-method for mycotoxins after single extraction, with validation data for peanut, pistachio, wheat, maize, cornflakes, raisins and figs.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20080401

Title: Ergot alkaloids in rye flour determined by solid-phase cation-exchange and high-pressure liquid chromatography with fluorescence detection.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20080301

Title: Use of a nonhomologous end joining deficient strain (Deltaku70) of the ergot fungus Claviceps purpurea for identification of a nonribosomal peptide synthetase gene involved in ergotamine biosynthesis.

Journal: Fungal genetics and biology : FG & B 20080101

Title: Determination of ergot alkaloids: purity and stability assessment of standards and optimization of extraction conditions for cereal samples.

Journal: Journal of AOAC International 20080101

Title: A comparative study of topical natural ergot alkaloids on the intraocular pressure and aqueous humor dynamics in oclular normotensive and alpha-chymotrypsin-induced ocular hypertensive rabbits.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20071001

Title: Ergot alkaloids in Norwegian wild grasses: a mass spectrometric approach.

Journal: Rapid communications in mass spectrometry : RCM 20070101

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Ergot alkaloids--biology and molecular biology.

Journal: The Alkaloids. Chemistry and biology 20060101

Title: Expression and regulation of progestin membrane receptors in the rat corpus luteum.

Journal: Endocrinology 20051201

Title: The influence of ergot-contaminated feed on growth and slaughtering performance, nutrient digestibility and carry over of ergot alkaloids in growing-finishing pigs.

Journal: Archives of animal nutrition 20051201

Title: Electrospray[+] tandem quadrupole mass spectrometry in the elucidation of ergot alkaloids chromatographed by HPLC: screening of grass or forage samples for novel toxic compounds.

Journal: Journal of mass spectrometry : JMS 20051101

Title: Comparative studies on the effect of ergot contaminated feed on performance and health of piglets and chickens.

Journal: Archives of animal nutrition 20050401

Title: Claviceps cyperi, a new cause of severe ergotism in dairy cattle consuming maize silage and teff hay contaminated with ergotised Cyperus esculentus (nut sedge) on the Highveld of South Africa.

Journal: The Onderstepoort journal of veterinary research 20050301

Title: Fragmentation patterns of selected ergot alkaloids by electrospray ionization tandem quadrupole mass spectrometry.

Journal: Journal of mass spectrometry : JMS 20041101

Title: Enantioefficient synthesis of alpha-ergocryptine: first direct synthesis of (+)-lysergic acid.

Journal: The Journal of organic chemistry 20040903

Title: Determination of plasma ziprasidone using liquid chromatography with fluorescence detection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040125

Title: Does mowing height influence alkaloid production in endophytic tall fescue and perennial ryegrass?

Journal: Journal of chemical ecology 20030601

Title: Interaction of cytochrome P450 3A inhibitors with P-glycoprotein.

Journal: The Journal of pharmacology and experimental therapeutics 20021001

Title: Ergot alkaloids produced by submerged cultures of Claviceps zizaniae.

Journal: Journal of natural products 20020701

Title: Technical note: epimerization of ergopeptine alkaloids in organic and aqueous solvents.

Journal: Journal of animal science 20020601

Title: Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein.

Journal: Molecular pharmacology 20020501

Title: The effect of topical natural ergot alkaloids on the intraocular pressure and aqueous humor dynamics in rabbits with alpha-chymotrypsin-induced ocular hypertension.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20020401

Title: Effects of topical natural ergot alkaloids on intraocular pressure and aqueous humor dynamics in ocular normotensive rabbits.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20020201

Title: [Isolation of the ergot (Claviceps purpurea (Fr.) Tul., strain VKM-F-366D), producing the lactamic alkaloid ergocornam].

Journal: Prikladnaia biokhimiia i mikrobiologiia 20020101

Title: Semiquantitative determination of ergot alkaloids in seed, straw, and digesta samples using a competitive enzyme-linked immunosorbent assay.

Journal: Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 20010501

Title: Ergot alkaloid transport across ruminant gastric tissues.

Journal: Journal of animal science 20010201

Title: Identification of residues in transmembrane regions III and VI that contribute to the ligand binding site of the serotonin 5-HT6 receptor.

Journal: Journal of neurochemistry 19981101

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Tags:511-09-1 Molecular Formula|511-09-1 MDL|511-09-1 SMILES|511-09-1 ALPHA-ERGOCRYPTINE