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Home Other Building Blocks 514814-49-4
514814-49-4,MFCD31657373
Catalog No.:AA01B4T1

514814-49-4 | PMX 205

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
98%
2 weeks  
$520.00   $364.00
- +
10mg
98%
2 weeks  
$758.00   $530.00
- +
25mg
98%
2 weeks  
$1,234.00   $864.00
- +
50mg
98%
2 weeks  
$1,710.00   $1,197.00
- +
100mg
98%
2 weeks  
$2,424.00   $1,697.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01B4T1
Chemical Name:
PMX 205
CAS Number:
514814-49-4
Molecular Formula:
C45H62N10O6
Molecular Weight:
839.0372
MDL Number:
MFCD31657373
SMILES:
O=C(N[C@H]1CCCNC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H]2N(C1=O)CCC2)CC1CCCCC1)Cc1c[nH]c2c1cccc2)CCc1ccccc1
Properties
Computed Properties
 
Complexity:
1530  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
5  
Heavy Atom Count:
61  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
8  
Rotatable Bond Count:
12  
XLogP3:
3.8  

Literature

Title: Increased potency of a novel complement factor 5a receptor antagonist in a rat model of inflammatory bowel disease.

Journal: The Journal of pharmacology and experimental therapeutics 20050801

Title: Kosni NN, et al. Expression of complement C5a receptor and the viability of 4T1 tumor cells following agonist-antagonist treatment. J Cancer Res Ther. 2016 Apr-Jun;12(2):590-6.

Title: Woodruff TM, et al. The complement factor C5a contributes to pathology in a rat model of amyotrophic lateral sclerosis. J Immunol. 2008 Dec 15;181(12):8727-34.

Title: Fonseca MI, et al. Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease. J Immunol. 2009 Jul 15;183(2):1375-83.

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SDS
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Tags:514814-49-4 Molecular Formula|514814-49-4 MDL|514814-49-4 SMILES|514814-49-4 PMX 205