Title: The PIGRET assay, a method for measuring Pig-a gene mutation in reticulocytes, is reliable as a short-term in vivo genotoxicity test: Summary of the MMS/JEMS-collaborative study across 16 laboratories using 24 chemicals.
Journal: Mutation research 20161115
Title: Chemotherapy drug thioTEPA exacerbates stress-induced anhedonia and corticosteroid responses but not impairment of hippocampal cell proliferation in adult mice.
Journal: Behavioural brain research 20130101
Title: Thiotepa and melphalan based single, tandem, and triple high dose therapy and autologous stem cell transplantation for high risk neuroblastoma.
Journal: Pediatric blood & cancer 20121215
Title: Efficient monitoring of in vivo pig-a gene mutation and chromosomal damage: summary of 7 published studies and results from 11 new reference compounds.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20121201
Title: Intensive chemotherapy with thiotepa, busulfan and cyclophosphamide and hematopoietic stem cell rescue in relapsed or refractory primary central nervous system lymphoma and intraocular lymphoma: a retrospective study of 79 cases.
Journal: Haematologica 20121101
Title: Single-unit umbilical cord blood transplantation from unrelated donors in patients with hematological malignancy using busulfan, thiotepa, fludarabine and ATG as myeloablative conditioning regimen.
Journal: Bone marrow transplantation 20121001
Title: High-dose thiotepa, etoposide and carboplatin as conditioning regimen for autologous stem cell transplantation in patients with high-risk non-Hodgkin lymphoma.
Journal: Clinical and experimental medicine 20120901
Title: Radiation-free allogeneic conditioning with fludarabine, carmustine, and thiotepa for acute lymphoblastic leukemia and other hematologic malignancies necessitating enhanced central nervous system activity.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20120901
Title: Mechanisms and kinetics of thiotepa and tepa hydrolysis: DFT study.
Journal: Journal of molecular modeling 20120801
Title: Allogeneic hematopoietic stem cell transplantation in thalassemia major: results of a reduced-toxicity conditioning regimen based on the use of treosulfan.
Journal: Blood 20120712
Title: Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Journal: Journal of medicinal chemistry 20120524
Title: Fludarabine, melphalan, thiotepa and anti-thymocyte globulin conditioning for unrelated cord blood transplant.
Journal: Leukemia & lymphoma 20120501
Title: Upfront thiotepa, busulfan, cyclophosphamide, and autologous stem cell transplantation for primary CNS lymphoma: a single centre experience.
Journal: Leukemia & lymphoma 20120501
Title: Salvage haploidentical transplantation for graft failure using reduced-intensity conditioning.
Journal: Bone marrow transplantation 20120301
Title: BU, melphalan and thiotepa as a preparative regimen for auto-transplantation in Hodgkin's disease.
Journal: Bone marrow transplantation 20120201
Title: Tandem high-dose chemotherapy and autologous stem cell transplantation in young children with atypical teratoid/rhabdoid tumor of the central nervous system.
Journal: Journal of Korean medical science 20120201
Title: Autologous stem cell transplantation with thiotepa, busulfan, and cyclophosphamide (TBC) conditioning in patients with CNS involvement by non-Hodgkin lymphoma.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20120101
Title: High-dose thiotepa, etoposide and carboplatin as conditioning regimen for autologous stem cell transplantation in patients with high-risk Hodgkin's lymphoma.
Journal: Hematology (Amsterdam, Netherlands) 20120101
Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Journal: PLoS computational biology 20111201
Title: [Sustained complete remission of intravascular large B-cell lymphoma with recurrent CNS involvement by autologous peripheral blood stem cell transplantation preconditioned with TBC regimen].
Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20111201
Title: Platine and cytarabine-based salvage treatment for primary central nervous system lymphoma.
Journal: Journal of neuro-oncology 20111101
Title: Therapeutic in vivo selection of thymic-derived natural T regulatory cells following non-myeloablative hematopoietic stem cell transplant for IPEX.
Journal: Clinical immunology (Orlando, Fla.) 20111101
Title: Phase I study of tandem high-dose chemotherapy with autologous peripheral blood stem cell rescue for children with recurrent brain tumors: a Pediatric Blood and MarrowTransplant Consortium study.
Journal: Pediatric blood & cancer 20110901
Title: An aCGH classifier derived from BRCA1-mutated breast cancer and benefit of high-dose platinum-based chemotherapy in HER2-negative breast cancer patients.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20110701
Title: New sequential treatment with chemotherapy and reduced-intensity conditioning for allogeneic stem-cell transplantation in very high-risk acute myeloid leukemia.
Journal: American journal of hematology 20110701
Title: Conventional-dose versus high-dose chemotherapy as first salvage treatment in male patients with metastatic germ cell tumors: evidence from a large international database.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110601
Title: A comprehensive understanding of thioTEPA metabolism in the mouse using UPLC-ESI-QTOFMS-based metabolomics.
Journal: Biochemical pharmacology 20110415
Title: Is radiotherapy an option for early breast cancers with complete clinical response after neoadjuvant chemotherapy?
Journal: International journal of radiation oncology, biology, physics 20110401
Title: Infratentorial brain metastases of pediatric non-epithelial malignant tumors: three case reports.
Journal: Brain tumor pathology 20110401
Title: Zebrafish (Danio rerio) embryos as a model for testing proteratogens.
Journal: Toxicology 20110315
Title: Intramedullary PNET of the spine: long-term survival after combined modality therapy and subsequent relapse.
Journal: Journal of pediatric hematology/oncology 20110301
Title: Clinical relevance of the dose of cytarabine in the upfront treatment of primary CNS lymphomas with methotrexate-cytarabine combination.
Journal: The oncologist 20110301
Title: [Randomized clinical case-control trial for the comparison of docetaxel plus thiotepa versus docetaxel plus capecitabine in patients with metastatic breast cancer].
Journal: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20110218
Title: MUC1-positive circulating tumor cells and MUC1 protein predict chemotherapeutic efficacy in the treatment of metastatic breast cancer.
Journal: Chinese journal of cancer 20110101
Title: DNA methyltransferase inhibitor CDA-2 synergizes with high-dose thiotepa and paclitaxel in killing breast cancer stem cells.
Journal: Frontiers in bioscience (Elite edition) 20110101
Title: Nicotinamide inhibits alkylating agent-induced apoptotic neurodegeneration in the developing rat brain.
Journal: PloS one 20110101
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: Toxicity of high-dose chemotherapy with etoposide, thiotepa and CY in treating poor-prognosis Ewing's sarcoma family tumors: the experience of the Bambino Gesù Children's Hospital.
Journal: Bone marrow transplantation 20100801
Title: Some physicochemical properties of the antitumor drug thiotepa and its metabolite tepa as obtained by density functional theory (DFT) calculations.
Journal: Journal of molecular modeling 20100801
Title: The chemotherapy agent, thioTEPA, yields long-term impairment of hippocampal cell proliferation and memory deficits but not depression-related behaviors in mice.
Journal: Behavioural brain research 20100501
Title: Remission re-induction chemotherapy with clofarabine, topotecan, thiotepa, and vinorelbine for patients with relapsed or refractory leukemia.
Journal: Pediatric blood & cancer 20100501
Title: Excessive toxicity of once daily i.v. BU, melphalan and thiotepa followed by auto SCT on patients with non-Hodgkin's lymphoma.
Journal: Bone marrow transplantation 20100401
Title: A phase II prospective study of sequential myeloablative chemotherapy with hematopoietic stem cell rescue for the treatment of selected high risk and recurrent central nervous system tumors.
Journal: Journal of neuro-oncology 20100401
Title: Thiotepa/topotecan/carboplatin with autologous stem cell rescue in recurrent/refractory/poor prognosis pediatric malignancies of the central nervous system.
Journal: Pediatric blood & cancer 20100401
Title: Reduced-intensity conditioning using fludarabine, melphalan and thiotepa for adult patients undergoing haploidentical SCT.
Journal: Bone marrow transplantation 20100301
Title: High-dose carboplatin, thiotepa, and etoposide with autologous stem cell rescue for patients with previously irradiated recurrent medulloblastoma.
Journal: Neuro-oncology 20100301
Title: Thiotepa, a reliable marker for sperm precedence measurement in a polyandrous moth.
Journal: Journal of insect physiology 20100101
Title: Cyclophosphamide-metabolizing enzyme polymorphisms and survival outcomes after adjuvant chemotherapy for node-positive breast cancer: a retrospective cohort study.
Journal: Breast cancer research : BCR 20100101
Title: Cytochrome P(450)-dependent toxic effects of primaquine on human erythrocytes.
Journal: Toxicology and applied pharmacology 20091115
Title: Outcome of patients with recurrent medulloblastoma or central nervous system germinoma treated with low dose continuous intravenous etoposide along with dose-intensive chemotherapy followed by autologous hematopoietic stem cell rescue.
Journal: Pediatric blood & cancer 20090701
Title: Impairment of APE1 function enhances cellular sensitivity to clinically relevant alkylators and antimetabolites.
Journal: Molecular cancer research : MCR 20090601
Title: Effect of tamoxifen on the endometrium and the menstrual cycle of premenopausal breast cancer patients.
Journal: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20090501
Title: No salvage using high-dose chemotherapy plus/minus reirradiation for relapsing previously irradiated medulloblastoma.
Journal: International journal of radiation oncology, biology, physics 20090401
Title: A multimodal strategy based on surgery, radiotherapy, ICE regimen and high dose chemotherapy in atypical teratoid/rhabdoid tumours: a single institution experience.
Journal: Journal of neuro-oncology 20090401
Title: Evaluation of osmolality and pH of various concentrations of methotrexate, cytarabine, and thiotepa prepared in normal saline, sterile water for injection, and lactated Ringer's solution for intrathecal administration.
Journal: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20090301
Title: Pharmacokinetics of cyclophosphamide and thiotepa in a conventional fractionated high-dose regimen compared with a novel simplified unfractionated regimen.
Journal: Therapeutic drug monitoring 20090201
Title: Survival after second-line intraperitoneal therapy for the treatment of epithelial ovarian cancer: the Gynecologic Oncology Group experience.
Journal: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20090201
Title: Altered cyclophosphamide and thiotepa pharmacokinetics in a patient with moderate renal insufficiency.
Journal: Cancer chemotherapy and pharmacology 20090101
Title: Polymorphisms of drug-metabolizing enzymes (GST, CYP2B6 and CYP3A) affect the pharmacokinetics of thiotepa and tepa.
Journal: British journal of clinical pharmacology 20090101
Title: Myeloablative chemotherapy with autologous bone marrow rescue in children and adolescents with recurrent malignant astrocytoma: outcome compared with conventional chemotherapy: a report from the Children's Oncology Group.
Journal: Pediatric blood & cancer 20081201
Title: Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Journal: Journal of medicinal chemistry 20081113
Title: Relations between polymorphisms in drug-metabolising enzymes and toxicity of chemotherapy with cyclophosphamide, thiotepa and carboplatin.
Journal: Pharmacogenetics and genomics 20081101
Title: Treosulfan-based conditioning regimen for allogeneic haematopoietic stem cell transplantation in patients with thalassaemia major.
Journal: British journal of haematology 20081101
Title: Risk factors for hepatic veno-occlusive disease: a retrospective unicentric study in 116 children autografted after a high-dose BU-thiotepa regimen.
Journal: Bone marrow transplantation 20081001
Title: Breast cancer management: the road to today.
Journal: Cancer 20081001
Title: High-dose chemotherapy with BEAM or Busulphan/Melphalan and Thiotepa followed by hematopoietic cell transplantation in malignant lymphoma.
Journal: Leukemia & lymphoma 20081001
Title: Structure-activity relationships of novel heteroaryl-acrylonitriles as cytotoxic and antibacterial agents.
Journal: European journal of medicinal chemistry 20080901
Title: A phase II study of intensified chemotherapy alone as initial treatment for newly diagnosed anaplastic oligodendroglioma: an interim analysis.
Journal: Journal of neuro-oncology 20080901
Title: The monoterpenoids citral and geraniol are moderate inhibitors of CYP2B6 hydroxylase activity.
Journal: Chemico-biological interactions 20080811
Title: The feasibility of using topotecan, vinorelbine, thiotepa and gemcitabine (TVTG) in adult patients with relapsed/refractory acute lymphoblastic leukaemia/lymphoma.
Journal: Leukemia 20080801
Title: Rituximab improves the efficacy of high-dose chemotherapy with autograft for high-risk follicular and diffuse large B-cell lymphoma: a multicenter Gruppo Italiano Terapie Innnovative nei linfomi survey.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080701
Title: Randomized trial of high-dose adjuvant chemotherapy with autologous hematopoietic stem-cell support versus standard-dose chemotherapy in breast cancer patients with 10 or more positive lymph nodes: overall survival after 6 years of follow-up.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20080601
Title: Intensive chemotherapy followed by hematopoietic stem-cell rescue for refractory and recurrent primary CNS and intraocular lymphoma: Société Française de Greffe de Moëlle Osseuse-Thérapie Cellulaire.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080520
Title: Feasibility of metronomic maintenance chemotherapy following high-dose chemotherapy for malignant central nervous system tumors.
Journal: Pediatric blood & cancer 20080501
Title: A fludarabine, thiotepa reduced toxicity conditioning regimen designed specifically for allogeneic second haematopoietic cell transplantation after failure of previous autologous or allogeneic transplantation.
Journal: Bone marrow transplantation 20080501
Title: High-dose chemotherapy with autologous stem cell transplantation in adults with recurrent embryonal tumors of the central nervous system.
Journal: Cancer 20080415
Title: Cutaneous effects of thiotepa in pediatric patients receiving high-dose chemotherapy with autologous stem cell transplantation.
Journal: Journal of the American Academy of Dermatology 20080401
Title: Symptom burden after autologous stem cell transplantation for multiple myeloma.
Journal: Cancer 20080401
Title: Treatment of children with metastatic soft tissue sarcoma with oral maintenance compared to high dose chemotherapy: report of the HD CWS-96 trial.
Journal: Pediatric blood & cancer 20080401
Title: Brain magnetic resonance imaging after high-dose chemotherapy and radiotherapy for childhood brain tumors.
Journal: International journal of radiation oncology, biology, physics 20080315
Title: Acute transient encephalopathy following paclitaxel treatment in an adolescent with a recurrent suprasellar germinoma.
Journal: Pediatric blood & cancer 20080301
Title: Brainstem primitive neuroectodermal tumors (bstPNET): results of treatment with intensive induction chemotherapy followed by consolidative chemotherapy with autologous hematopoietic cell rescue.
Journal: Pediatric blood & cancer 20080301
Title: Pegase 03: a prospective randomized phase III trial of FEC with or without high-dose thiotepa, cyclophosphamide and autologous stem cell transplantation in first-line treatment of metastatic breast cancer.
Journal: Bone marrow transplantation 20080301
Title: Haploidentical allogeneic hematopoietic cell transplantation in adults using CD3/CD19 depletion and reduced intensity conditioning: an update.
Journal: Blood cells, molecules & diseases 20080101
Title: Phase III study to evaluate the use of high-dose chemotherapy as consolidation of treatment for high-risk postoperative breast cancer: Japan Clinical Oncology Group study, JCOG 9208.
Journal: Cancer science 20080101
Title: Wound healing in patients with cancer.
Journal: Eplasty 20080101
Title: Thiotepa/cyclophosphamide/TBI as a conditioning regimen for allogeneic hematopoietic stem cell transplantation in patients aged 50 years and over.
Journal: Internal medicine (Tokyo, Japan) 20080101
Title: High-dose chemotherapy with autologous stem cell rescue in stage IIIB inflammatory breast cancer.
Journal: Anticancer research 20080101
Title: Prospective study of long-term impact of adjuvant high-dose and conventional-dose chemotherapy on health-related quality of life.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071201
Title: The effect of high-dose thiotepa, alone or in combination with other chemotherapeutic agents, on a murine B-cell leukemia model simulating autologous stem cell transplantation.
Journal: Bone marrow transplantation 20071101
Title: Elevated plasma ferritin and busulfan pharmacodynamics during high-dose chemotherapy regimens in children with malignant solid tumors.
Journal: Clinical pharmacology and therapeutics 20071001
Title: [A case of recurrent renal cell carcinoma which recurred after fourth surgical resection and survived for about 2 years by medroxyporgesterone acetate administration].
Journal: Hinyokika kiyo. Acta urologica Japonica 20070901
Title: Outcome for young children newly diagnosed with ependymoma, treated with intensive induction chemotherapy followed by myeloablative chemotherapy and autologous stem cell rescue.
Journal: Pediatric blood & cancer 20070701
Title: Parvovirus B19 pneumonia in a child undergoing allogeneic hematopoietic stem cell transplantation.
Journal: Bone marrow transplantation 20070701
Title: High-dose chemotherapy with autologous stem cell rescue followed by posterior fossa irradiation for local medulloblastoma recurrence or progression after conventional chemotherapy.
Journal: Cancer 20070701
Title: High-dose cyclophosphamide inhibition of humoral immune response to murine monoclonal antibody 3F8 in neuroblastoma patients: broad implications for immunotherapy.
Journal: Pediatric blood & cancer 20070401
Title: A chemosensitivity test for superficial bladder cancer based on three-dimensional culture of tumour spheroids.
Journal: European urology 20070401
Title: Primary central nervous system lymphoma treated with high-dose methotrexate, high-dose busulfan/thiotepa, autologous stem-cell transplantation and response-adapted whole-brain radiotherapy: results of the multicenter Ostdeutsche Studiengruppe Hamato-Onkologie OSHO-53 phase II study.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20070401
Title: Long-term follow-up of the SBG 9401 study comparing tailored FEC-based therapy versus marrow-supported high-dose therapy.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20070401
Title: Reduced intensity conditioning with thiotepa, fludarabine, and melphalan is effective in advanced multiple myeloma.
Journal: Leukemia & lymphoma 20070401
Title: Outcome for children <4 years of age with malignant central nervous system tumors treated with high-dose chemotherapy and autologous stem cell rescue.
Journal: Pediatric blood & cancer 20070301
Title: Survival benefit with GM-CSF use after high-dose chemotherapy in high-risk breast cancer.
Journal: Tumori 20070101
Title: Contribution of CYP2C9, CYP2A6, and CYP2B6 to valproic acid metabolism in hepatic microsomes from individuals with the CYP2C9*1/*1 genotype.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20061201
Title: Molecular subtypes of breast cancer and amplification of topoisomerase II alpha: predictive role in dose intensive adjuvant chemotherapy.
Journal: British journal of cancer 20061120
Title: A case of relapsing glioblastoma multiforme responding to vinorelbine.
Journal: Journal of neuro-oncology 20061101
Title: In-vitro toxicity of Ukrain against human Ewing tumor cell lines.
Journal: Anti-cancer drugs 20061001
Title: Potent inhibition of cell proliferation in the hippocampal dentate gyrus of mice by the chemotherapeutic drug thioTEPA.
Journal: Brain research 20060921
Title: RAT CYP3A and CYP2B1/2 were not associated with nevirapine-induced hepatotoxicity.
Journal: Methods and findings in experimental and clinical pharmacology 20060901
Title: High-dose chemotherapy with autologous stem-cell transplantation and hyperfractionated radiotherapy as first-line treatment of primary CNS lymphoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060820
Title: Breast cancer-specific mRNA transcripts presence in peripheral blood after adjuvant chemotherapy predicts poor survival among high-risk breast cancer patients treated with high-dose chemotherapy with peripheral blood stem cell support.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060801
Title: Stereoselective metabolism of endosulfan by human liver microsomes and human cytochrome P450 isoforms.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20060701
Title: [A case of recurrent breast cancer complicated with pericardial effusions and cardiac tamponade].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20060701
Title: MATILDE regimen followed by radiotherapy is an active strategy against primary CNS lymphomas.
Journal: Neurology 20060509
Title: High exposures to bioactivated cyclophosphamide are related to the occurrence of veno-occlusive disease of the liver following high-dose chemotherapy.
Journal: British journal of cancer 20060508
Title: High-dose chemotherapy and autologous peripheral blood stem cell transplantation for primary breast cancer refractory to neoadjuvant chemotherapy.
Journal: Bone marrow transplantation 20060501
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Successful autologous peripheral blood stem cell transplantation using thiotepa in a patient with systemic sclerosis and cardiac involvement.
Journal: The Tohoku journal of experimental medicine 20060501
Title: Efficacy of high-dose alkylating chemotherapy in HER2/neu-negative breast cancer.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20060401
Title: High-dose chemotherapy with stem cell rescue as initial therapy for anaplastic oligodendroglioma: long-term follow-up.
Journal: Neuro-oncology 20060401
Title: Supratentorial primitive neuroectodermal tumors (S-PNET) in children: A prospective experience with adjuvant intensive chemotherapy and hyperfractionated accelerated radiotherapy.
Journal: International journal of radiation oncology, biology, physics 20060315
Title: Topotecan, thiotepa, and carboplatin for neuroblastoma: failure to prevent relapse in the central nervous system.
Journal: Bone marrow transplantation 20060201
Title: Bone marrow mammaglobin expression as a marker of graft-versus-tumor effect after reduced-intensity allografting for advanced breast cancer.
Journal: Bone marrow transplantation 20060201
Title: Correlations between the activities of 19 anti-tumor agents and the intracellular glutathione concentrations in a panel of 14 human cancer cell lines: comparisons with the National Cancer Institute data.
Journal: Anti-cancer drugs 20060101
Title: Phase I/II study of tandem cycles of high-dose chemotherapy followed by autologous hematopoietic stem cell support in women with advanced ovarian cancer.
Journal: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101
Title: High-dose busulfan and thiotepa followed by autologous stem cell transplantation (ASCT) in previously irradiated medulloblastoma patients: high toxicity and lack of efficacy.
Journal: Bone marrow transplantation 20051201
Title: Population pharmacokinetics of cyclophosphamide and its metabolites 4-hydroxycyclophosphamide, 2-dechloroethylcyclophosphamide, and phosphoramide mustard in a high-dose combination with Thiotepa and Carboplatin.
Journal: Therapeutic drug monitoring 20051201
Title: Amsacrine combined with etoposide and high-dose methylprednisolone as salvage therapy in acute lymphoblastic leukemia in children.
Journal: Haematologica 20051201
Title: Lasting remission following multimodal treatment in a patient with metastatic breast cancer.
Journal: Anti-cancer drugs 20051101
Title: Aprepitant inhibits cyclophosphamide bioactivation and thiotepa metabolism.
Journal: Cancer chemotherapy and pharmacology 20051001
Title: Excessive toxicity of the high dose thiotepa and etoposide regimen when combined with radiation: Long-term autologous transplantation experience in follicular and mantle cell lymphoma.
Journal: Leukemia & lymphoma 20051001
Title: Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
Journal: Current drug metabolism 20051001
Title: Bladder cancer: current optimal intravesical treatment.
Journal: Urologic nursing 20051001
Title: Reduced intensity conditioning for allograft after cytoreductive autograft in metastatic breast cancer.
Journal: Lancet (London, England) 20050701
Title: The extent of chromosomal aberrations induced by chemotherapy in non-human primates depends on the schedule of administration.
Journal: Mutation research 20050606
Title: The naturally occurring cytochrome P450 (P450) 2B6 K262R mutant of P450 2B6 exhibits alterations in substrate metabolism and inactivation.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20050601
Title: Sparse sampling design for therapeutic drug monitoring of sequentially administered cyclophosphamide, thiotepa, and carboplatin (CTC).
Journal: Therapeutic drug monitoring 20050601
Title: High-dose chemotherapy and autologous stem cell rescue for metastatic breast cancer: superior survival for tandem compared with single transplants.
Journal: American journal of clinical oncology 20050601
Title: Management of leptomeningeal malignancy.
Journal: Expert opinion on pharmacotherapy 20050601
Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.
Journal: Chemical research in toxicology 20050601
Title: Glutamine as a neuroprotective agent in high-dose paclitaxel-induced peripheral neuropathy: a clinical and electrophysiologic study.
Journal: Clinical oncology (Royal College of Radiologists (Great Britain)) 20050601
Title: Significant induction of cyclophosphamide and thiotepa metabolism by phenytoin.
Journal: Cancer chemotherapy and pharmacology 20050501
Title: High-dose etoposide, thiotepa, and dose-adjusted carboplatin (TVCa) with autologous hematopoietic stem cell rescue as treatment of relapsed or refractory germ cell cancer.
Journal: American journal of clinical oncology 20050401
Title: Inhibition of human CYP2B6 by N,N',N''-triethylenethiophosphoramide is irreversible and mechanism-based.
Journal: Biochemical pharmacology 20050201
Title: Accuracy, feasibility, and clinical impact of prospective Bayesian pharmacokinetically guided dosing of cyclophosphamide, thiotepa, and carboplatin in high-dose chemotherapy.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050101
Title: Sequential chemotherapy, high-dose thiotepa, circulating progenitor cell rescue, and radiotherapy for childhood high-grade glioma.
Journal: Neuro-oncology 20050101
Title: High-dose chemotherapy with autologous stem cell rescue for children with high risk and recurrent medulloblastoma and supratentorial primitive neuroectodermal tumors.
Journal: Journal of neuro-oncology 20050101
Title: Combined treatment of metastatic breast cancer (MBC) by high-dose chemotherapy (HDCT) and bispecific antibodies: a pilot study.
Journal: Anticancer research 20050101
Title: [Berberine and amitozine binding with calf thymus DNA].
Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20050101
Title: Reduced-intensity conditioning regimen with thiotepa and fludarabine followed by allogeneic blood stem cell transplantation in haematological malignancies.
Journal: Bone marrow transplantation 20041201
Title: The use of high-dose cyclophosphamide, carmustine, and thiotepa plus autologous hematopoietic stem cell transplantation as consolidation therapy for high-risk primary breast cancer after primary surgery or neoadjuvant chemotherapy.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20041101
Title: High dose chemotherapy with thiotepa, mitoxantrone and carboplatin (TMJ) followed by autologous stem cell support in 100 consecutive lymphoma patients in a single centre: analysis of efficacy, toxicity and prognostic factors.
Journal: Leukemia & lymphoma 20041101
Title: Metabolism of N,N',N'-triethylenethiophosphoramide by CYP2B1 and CYP2B6 results in the inactivation of both isoforms by two distinct mechanisms.
Journal: The Journal of pharmacology and experimental therapeutics 20040901
Title: CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20040901
Title: The treatment of neoplastic meningitis.
Journal: Expert opinion on pharmacotherapy 20040901
Title: Oral fluconazole for empiric treatment of prolonged Fever in neutropenic patients: prospective study in 250 consecutive patients after stem cell transplantation.
Journal: American journal of clinical oncology 20040801
Title: Cardiac toxicity observed in association with high-dose cyclophosphamide-based chemotherapy for metastatic breast cancer.
Journal: Breast (Edinburgh, Scotland) 20040801
Title: Treatment of relapsed Wilms' tumor with high-dose therapy and autologous hematopoietic stem-cell rescue: the experience at Children's Memorial Hospital.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040715
Title: Randomized Phase II trial of two high-dose chemotherapy regimens with stem cell transplantation for the treatment of advanced ovarian cancer in first remission or chemosensitive relapse: a Southwest Oncology Group study.
Journal: Gynecologic oncology 20040701
Title: Comparison of high-dose melphalan with a more intensive regimen of thiotepa, busulfan, and cyclophosphamide for patients with multiple myeloma.
Journal: Cancer 20040615
Title: Selective inhibition of CYP2B6-catalyzed bupropion hydroxylation in human liver microsomes in vitro.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20040601
Title: High-dose chemotherapy and autologous stem cell transplant in women with de novo chemosensitive metastatic breast cancer.
Journal: American journal of clinical oncology 20040601
Title: High dose chemotherapy and autologous stem cell transplantation for poor risk and recurrent non-Hodgkin's lymphoma: a single-center experience of 50 patients.
Journal: The Korean journal of internal medicine 20040601
Title: Safety and efficacy of high-dose chemotherapy with autologous stem cell transplantation for patients with malignant astrocytomas.
Journal: Cancer 20040515
Title: High-dose thiotepa and etoposide in children with poor-prognosis brain tumors.
Journal: Cancer 20040515
Title: Thiotepa/cyclophosphamide/TBI as a conditioning regimen for allogeneic hematopoietic stem cell transplantation in patients with myelodysplastic syndrome.
Journal: Bone marrow transplantation 20040401
Title: Integrated Population Pharmacokinetic Model of both cyclophosphamide and thiotepa suggesting a mutual drug-drug interaction.
Journal: Journal of pharmacokinetics and pharmacodynamics 20040401
Title: Simultaneous quantification of cyclophosphamide, 4-hydroxycyclophosphamide, N,N',N'-triethylenethiophosphoramide (thiotepa) and N,N',N'-triethylenephosphoramide (tepa) in human plasma by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.
Journal: Journal of mass spectrometry : JMS 20040301
Title: Treatment-induced leukoencephalopathy in primary CNS lymphoma: a clinical and autopsy study.
Journal: Neurology 20040210
Title: [Results of intensive chemotherapy followed by hematopoietic stem-cell rescue in 22 patients with refractory or recurrent primary CNS lymphoma or intraocular lymphoma].
Journal: Bulletin du cancer 20040201
Title: [Refractory germ cell cancer of testis treated by salvage high-dose chemotherapy: report of three cases].
Journal: Hinyokika kiyo. Acta urologica Japonica 20040201
Title: A novel preparative regimen for autologous transplant in non-Hodgkin's lymphoma: long-term experience with etoposide and thiotepa.
Journal: Bone marrow transplantation 20040101
Title: High-dose chemotherapy with autologous stem cell rescue as first line of treatment in young children with medulloblastoma and supratentorial primitive neuroectodermal tumors.
Journal: Journal of neuro-oncology 20040101
Title: Double allogeneic peripheral blood stem cell transplantation in a 9-year-old patient with relapsed acute lymphoblastic leukemia: case report.
Journal: Pediatric hematology and oncology 20040101
Title: T1-T2 breast cancer with four or more positive axillary lymph nodes: adjuvant locoregional radiotherapy with high-dose or standard-dose chemotherapy. Results of an observational study.
Journal: Tumori 20040101
Title: Secondary acute leukemia following mitoxantrone-based high-dose chemotherapy for primary breast cancer patients.
Journal: Bone marrow transplantation 20031201
Title: Eye-preservation treatment of retinoblastoma with vitreous seeding.
Journal: Japanese journal of clinical oncology 20031201
Title: In children and adolescents, the pharmacodynamics of high-dose busulfan is dependent on the second alkylating agent used in the combined regimen (melphalan or thiotepa).
Journal: Bone marrow transplantation 20031101
Title: High-dose chemotherapy with stem cell rescue as initial therapy for anaplastic oligodendroglioma.
Journal: Journal of neuro-oncology 20031101
Title: Quality of life in women with breast cancer during the first year after random assignment to adjuvant treatment with marrow-supported high-dose chemotherapy with cyclophosphamide, thiotepa, and carboplatin or tailored therapy with Fluorouracil, epirubicin, and cyclophosphamide: Scandinavian Breast Group Study 9401.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031001
Title: A new multidrug reinduction protocol with topotecan, vinorelbine, thiotepa, dexamethasone, and gemcitabine for relapsed or refractory acute leukemia.
Journal: Leukemia 20031001
Title: Autologous stem cell transplantation for Hodgkin's disease: busulfan, melphalan and thiotepa compared to a radiation-based regimen.
Journal: Bone marrow transplantation 20030801
Title: High-dose chemotherapy with hematopoietic stem-cell rescue for high-risk breast cancer.
Journal: The New England journal of medicine 20030703
Title: Conventional adjuvant chemotherapy with or without high-dose chemotherapy and autologous stem-cell transplantation in high-risk breast cancer.
Journal: The New England journal of medicine 20030703
Title: Safety and outcome after fludarabine-thiotepa-TBI conditioning for allogeneic transplantation: a prospective study of 30 patients with hematologic malignancies.
Journal: Bone marrow transplantation 20030701
Title: Toxicity of the high-dose chemotherapy CTC regimen (cyclophosphamide, thiotepa, carboplatin): the Netherlands Cancer Institute experience.
Journal: British journal of cancer 20030616
Title: Idiopathic pneumonia syndrome after high-dose chemotherapy and autologous hematopoietic stem cell transplantation for high-risk breast cancer.
Journal: Bone marrow transplantation 20030601
Title: Double high-dose chemotherapy with adriamycin, paclitaxel, cyclophosphamide, and thiotepa followed by autologous peripheral blood stem cell transplantation in women with metastatic breast cancer.
Journal: Journal of cancer research and clinical oncology 20030601
Title: Adjuvant treatment of high-risk stage II breast cancer with doxorubicin followed by high-dose chemotherapy and autologous stem-cell transplantation: a single-institution experience with 132 consecutive patients.
Journal: Bone marrow transplantation 20030401
Title: High-dose thiotepa, busulfan, cyclophosphamide and ASCT without whole-brain radiotherapy for poor prognosis primary CNS lymphoma.
Journal: Bone marrow transplantation 20030401
Title: Successful engraftment and stable full donor chimerism after myeloablation with thiotepa, fludarabine, and melphalan and CD34-selected peripheral allogeneic stem cell transplantation in hemophagocytic lymphohistiocytosis.
Journal: American journal of hematology 20030201
Title: High-dose consolidation chemotherapy with Idarubicin and alkylating agents following induction with gemcitabine-epirubicin-paclitaxel in metastatic breast cancer: a dose finding study.
Journal: Bone marrow transplantation 20030201
Title: [Effect of bcl-2 antisense oligonucleotides on multidrug resistance of cultured uveal melanoma cells].
Journal: [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20030201
Title: A novel case of a CAT to AAT transversion in codon 179 of the p53 gene in a supratentorial primitive neuroectodermal tumor harbored by a young girl. Case report and review of the literature.
Journal: Oncology 20030101
Title: Palliative chemotherapy after failure of high-dose chemotherapy in breast cancer--toxicity and efficacy.
Journal: Anticancer research 20030101
Title: Nonablative hematopoietic cell transplantation for the treatment of metastatic renal cell carcinoma.
Journal: Bone marrow transplantation 20021201
Title: High-dose chemotherapy with autologous stem cell rescue in children with nephroblastoma.
Journal: Bone marrow transplantation 20021201
Title: A phase I/II study of 4 monthly courses of high-dose cyclophosphamide and thiotepa for metastatic breast cancer patients.
Journal: British journal of cancer 20021104
Title: Possible benefits of high-dose chemotherapy and autologous stem cell transplantation for adults with recurrent medulloblastoma.
Journal: Bone marrow transplantation 20021101
Title: Relationship between irreversible alopecia and exposure to cyclophosphamide, thiotepa and carboplatin (CTC) in high-dose chemotherapy.
Journal: Bone marrow transplantation 20021101
Title: Allelic variants of the human glutathione S-transferase P1 gene confer differential cytoprotection against anticancer agents in Escherichia coli.
Journal: Pharmacogenetics 20021001
Title: Extremely high exposures in an obese patient receiving high-dose cyclophosphamide, thiotepa and carboplatin.
Journal: Cancer chemotherapy and pharmacology 20020901
Title: Phase II trial of sequential high-dose chemotherapy with paclitaxel, melphalan and cyclophosphamide, thiotepa and carboplatin with peripheral blood progenitor support in women with responding metastatic breast cancer.
Journal: Bone marrow transplantation 20020801
Title: Toxicity of high-dose carboplatin: ultrafiltered and not total plasma pharmacokinetics is of clinical relevance.
Journal: Journal of clinical pharmacology 20020701
Title: Cytochrome P450 isozymes 3A4 and 2B6 are involved in the in vitro human metabolism of thiotepa to TEPA.
Journal: Cancer chemotherapy and pharmacology 20020601
Title: Triethylenethiophosphoramide is a specific inhibitor of cytochrome P450 2B6: implications for cyclophosphamide metabolism.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20020501
Title: Enhanced antitumor activity of irofulven in combination with thiotepa or mitomycin C.
Journal: Cancer chemotherapy and pharmacology 20020501
Title: Factors affecting progression-free survival in hormone-dependent metastatic breast cancer patients receiving high-dose chemotherapy and hematopoietic progenitor cell transplantation: role of maintenance endocrine therapy.
Journal: Bone marrow transplantation 20020501
Title: High-dose chemotherapy in poor-prognosis adult small round-cell tumors: clinical and molecular results from a prospective study.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020415
Title: Sensitivity of p53-deficient cells to oxaliplatin and thio-TEPA (N, N', N' triethylenethiophosphoramide).
Journal: Breast cancer research and treatment 20020401
Title: Relationship between exposure and toxicity in high-dose chemotherapy with cyclophosphamide, thiotepa and carboplatin.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20020301
Title: Epstein-Barr virus-associated lymphoma in a child undergoing an autologous stem cell rescue.
Journal: Journal of pediatric hematology/oncology 20020201
Title: Reduced-intensity conditioning followed by allografting of hematopoietic cells can produce clinical and molecular remissions in patients with poor-risk hematologic malignancies.
Journal: Blood 20020101
Title: The status of high-dose chemotherapy with hematopoietic stem cell transplantation in germ cell tumor patients.
Journal: Haematologica 20020101
Title: Isolex 300i CD34-selected cells to support multiple cycles of high-dose therapy.
Journal: Cytotherapy 20020101
Title: CliniMACS CD34-selected cells to support multiple cycles of high-dose therapy.
Journal: Cytotherapy 20020101
Title: The impact of induction duration and the number of high-dose cycles on the long-term survival of women with metastatic breast cancer treated with high-dose chemotherapy with stem cell rescue: an analysis of sequential phase I/II trials from the Dana-Farber/Beth Israel STAMP program.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20020101
Title: Pharmacological considerations of primary alkylators.
Journal: Cancer treatment and research 20020101
Title: Oral ftorafur plus intramuscular thiotepa as adjuvant chemotherapy in patients with breast cancer.
Journal: Medical oncology (Northwood, London, England) 20020101
Title: Intrathecal chemotherapy in carcinomatous meningitis from breast cancer.
Journal: Anticancer research 20020101
Title: Acute and late toxicity following adjuvant high-dose chemotherapy for high-risk primary operable breast cancer--a quality assessment study.
Journal: Acta oncologica (Stockholm, Sweden) 20020101
Title: Infectious complications in breast cancer patients undergoing peripheral blood stem cell transplantation: a single center retrospective analysis towards outpatient strategy.
Journal: Bone marrow transplantation 20011101
Title: Standardized, unrelated donor cord blood transplantation in adults with hematologic malignancies.
Journal: Blood 20011015
Title: [Modeling the periodically-changing predictable response to mutagen exposure in CBA/LacY mice in a successive inbred generations].
Journal: Genetika 20011001
Title: Topotecan combined with myeloablative doses of thiotepa and carboplatin for neuroblastoma, brain tumors, and other poor-risk solid tumors in children and young adults.
Journal: Bone marrow transplantation 20010901
Title: Thiotepa and fludarabine (TT-FLUDA) as conditioning regimen in poor candidates for conventional allogeneic hemopoietic stem cell transplant.
Journal: Annals of hematology 20010901
Title: [Hematopoietic stem cell transplantation with busulfanthiotepa-cyclophosphamide conditioning for pediatric patients with high-risk acute lymphoblastic leukemia].
Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20010901
Title: Thiotepa, busulfan, and cyclophosphamide as a preparative regimen for allogeneic transplantation for advanced myelodysplastic syndrome and acute myelogenous leukemia.
Journal: American journal of hematology 20010801
Title: Treatment of aggressive non-Hodgkin's lymphoma in elderly patients with thiotepa, Novantrone (mitoxantrone), vincristine, prednisone (TNOP).
Journal: American journal of clinical oncology 20010801
Title: Retrovirus-mediated expression of the base excision repair proteins, formamidopyrimidine DNA glycosylase or human oxoguanine DNA glycosylase, protects hematopoietic cells from N,N',N'-triethylenethiophosphoramide (thioTEPA)-induced toxicity in vitro and in vivo.
Journal: Cancer research 20010701
Title: Urinary excretion of thioTEPA and its metabolites in patients treated with high-dose cyclophosphamide, thioTEPA and carboplatin.
Journal: Anti-cancer drugs 20010701
Title: Phase II study of a multi-course high-dose chemotherapy regimen incorporating cyclophosphamide, thiotepa, and carboplatin in stage IV breast cancer.
Journal: Bone marrow transplantation 20010701
Title: A general family of distributions for longitudinal dependence with special reference to event histories.
Journal: Statistics in medicine 20010615
Title: Feasibility and low toxicity of early radiotherapy after high-dose chemotherapy and autologous stem cell transplantation for patients with high-risk stage II-III and locally advanced breast carcinoma.
Journal: Cancer 20010601
Title: A mechanism-based pharmacokinetic model for the cytochrome P450 drug-drug interaction between cyclophosphamide and thioTEPA and the autoinduction of cyclophosphamide.
Journal: Journal of pharmacokinetics and pharmacodynamics 20010601
Title: Telomere length in breast cancer patients before and after chemotherapy with or without stem cell transplantation.
Journal: British journal of cancer 20010501
Title: Thiotepa, busulfan, cyclophosphamide (TBC) and autologous hematopoietic transplantation: an intensive regimen for the treatment of multiple myeloma.
Journal: Bone marrow transplantation 20010401
Title: Randomized trials of high dose chemotherapy for breast cancer.
Journal: Biochimica et biophysica acta 20010321
Title: Total body irradiation before allogeneic bone marrow transplantation: is more dose better?
Journal: International journal of radiation oncology, biology, physics 20010315
Title: Protection of mammalian cells against chemotherapeutic agents thiotepa, 1,3-N,N'-bis(2-chloroethyl)-N-nitrosourea, and mafosfamide using the DNA base excision repair genes Fpg and alpha-hOgg1: implications for protective gene therapy applications.
Journal: The Journal of pharmacology and experimental therapeutics 20010301
Title: Severe interstitial pneumonitis following high-dose cyclophosphamide, thiotepa and docetaxel: two case reports and a review of the literature.
Journal: Bone marrow transplantation 20010301
Title: Recurrent disseminated retinoblastoma in a 7-year-old girl treated successfully by high-dose chemotherapy and CD34-selected autologous peripheral blood stem cell transplantation.
Journal: Bone marrow transplantation 20010301
Title: Results of intensive chemotherapy followed by hematopoietic stem-cell rescue in 22 patients with refractory or recurrent primary CNS lymphoma or intraocular lymphoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010201
Title: How effective is dose-intensive/myeloablative therapy against Ewing's sarcoma/primitive neuroectodermal tumor metastatic to bone or bone marrow? The Memorial Sloan-Kettering experience and a literature review.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010201
Title: Fatal upper and lower gastrointestinal cytomegalovirus disease following autologous peripheral blood stem cell transplantation.
Journal: European journal of haematology 20010201
Title: Salvage treatment with paclitaxel, ifosfamide, and cisplatin plus high-dose carboplatin, etoposide, and thiotepa followed by autologous stem-cell rescue in patients with relapsed or refractory germ cell cancer.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010101
Title: Population pharmacokinetics of thioTEPA and its active metabolite TEPA in patients undergoing high-dose chemotherapy.
Journal: British journal of clinical pharmacology 20010101
Title: The pharmacokinetics and pharmacodynamics of high-dose paclitaxel monotherapy (825 mg/m2 continuous infusion over 24 h) with hematopoietic support in women with metastatic breast cancer.
Journal: Cancer chemotherapy and pharmacology 20010101
Title: Comparison of double and triple high-dose chemotherapy with autologous blood stem cell transplantation in patients with metastatic breast cancer.
Journal: Stem cells (Dayton, Ohio) 20010101
Title: High-dose thiotepa and melphalan with hemopoietic progenitor support following induction therapy with epirubicin-paclitaxel-containing regimens in metastatic breast cancer (MBC).
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20010101
Title: Impact of intravesical chemotherapy on recurrence rate of recurrent superficial transitional cell carcinoma of the bladder: results of a meta-analysis.
Journal: Anticancer research 20010101
Title: Intrathecal chemotherapy with antineoplastic agents in children.
Journal: Paediatric drugs 20010101
Title: Neurophysiological evaluation of late effects of adjuvant high-dose chemotherapy on cognitive function.
Journal: Journal of neuro-oncology 20010101
Title: Systemic fusariosis after a preparative regimen including thiotepa, VP-16 and busulfan used for blood stem cell transplantation in Hodgkin's disease.
Journal: Leukemia & lymphoma 20010101
Title: Analyzing counts, durations, and recurrences in clinical trials.
Journal: Journal of biopharmaceutical statistics 20010101
Title: Overview of the treatment of infant central nervous system tumors: medulloblastoma as a model.
Journal: Journal of pediatric hematology/oncology 20010101
Title: Results of a prospective study with high-dose etoposide, thiotepa and carboplatin and peripheral blood stem cell rescue for high-risk stage II-IIIA and selected stage IV breast cancer patients.
Journal: Tumori 20010101
Title: New combinations with Herceptin in metastatic breast cancer.
Journal: Oncology 20010101
Title: Activity of allelic variants of Pi class human glutathione S-transferase toward chlorambucil.
Journal: Biochemical and biophysical research communications 20001111
Title: Individualizing high-dose oral busulfan: prospective dose adjustment in a pediatric population undergoing allogeneic stem cell transplantation for advanced hematologic malignancies.
Journal: Bone marrow transplantation 20000901
Title: Chemistry, pharmacology and pharmacokinetics of N,N',N' -triethylenethiophosphoramide (ThioTEPA).
Journal: Cancer treatment reviews 20000801
Title: Pilot trial of cytoprotection with amifostine given with high-dose chemotherapy and autologous peripheral blood stem cell transplantation.
Journal: American journal of clinical oncology 20000801
Title: High-dose carmustine, thiotepa and etoposide followed by autologous bone marrow rescue for the treatment of high risk central nervous system tumors.
Journal: Bone marrow transplantation 20000701
Title: [Establishment of MRP-overexpression subline of bladder carcinoma and its MDR phenotype].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20000701
Title: Susceptibility to drug-induced apoptosis correlates with differential modulation of Bad, Bcl-2 and Bcl-xL protein levels.
Journal: Cell death and differentiation 20000601
Title: Myeloablative chemotherapy for recurrent aggressive oligodendroglioma.
Journal: Neuro-oncology 20000401
Title: Inappropriate antidiuretic hormone secretion after high-dose thiotepa.
Journal: Bone marrow transplantation 19990901
Title: Differential catalytic efficiency of allelic variants of human glutathione S-transferase Pi in catalyzing the glutathione conjugation of thiotepa.
Journal: Archives of biochemistry and biophysics 19990601
Title: Thiotepa, busulfan and cyclophosphamide as a preparative regimen for allogeneic transplantation for advanced chronic myelogenous leukemia.
Journal: Bone marrow transplantation 19990501
Title: Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancers.
Journal: Oncogene 19990401
Title: Hprt mutant frequency and molecular analysis of Hprt mutations in Fischer 344 rats treated with thiotepa.
Journal: Carcinogenesis 19990201
Title: Veno-occlusive disease of the liver after busulfan, melphalan, and thiotepa conditioning therapy: incidence, risk factors, and outcome.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 19990101
Title: Thiotepa-associated cardiomyopathy during blood or marrow transplantation: association with the female sex and cardiac risk factors.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 19990101
Title: Phase I trial of sequential high-dose chemotherapy with escalating dose paclitaxel, melphalan, and cyclophosphamide, thiotepa, and carboplatin with peripheral blood progenitor support in women with responding metastatic breast cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 19980701
Title: [A comparative study of thio-tepa and mitomycin C in the treatment of pterygium. Preliminary results].
Journal: Journal francais d'ophtalmologie 19980201
Title: Transforming growth factor-beta 1 overexpression produces drug resistance in vivo: reversal by decorin.
Journal: In vivo (Athens, Greece) 19970101
Title: Therapeutic activity of CPT-11, a DNA-topoisomerase I inhibitor, against peripheral primitive neuroectodermal tumour and neuroblastoma xenografts.
Journal: British journal of cancer 19960801
Title: [Paraplegia following intrathecal chemotherapy].
Journal: Schweizerische medizinische Wochenschrift 19960622
Title: Intravesical thiotepa-induced eosinophilic cystitis.
Journal: Urology 19951101
Title: Bladder tumours following chemotherapy and radiotherapy for ovarian cancer: a case-control study.
Journal: International journal of cancer 19950927
Title: The role of human glutathione S-transferase isoenzymes in the formation of glutathione conjugates of the alkylating cytostatic drug thiotepa.
Journal: Cancer research 19950415
Title: A phase II trial of vinorelbine and thiotepa in metastatic breast cancer.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 19950201
Title: Multiple myeloma after treatment of essential thrombocythemia.
Journal: Southern medical journal 19950101
Title: Acquired episodic complete heart block after high-dose chemotherapy with cyclophosphamide and thiotepa.
Journal: American heart journal 19940301
Title: A phase I-II study of high-dose cyclophosphamide, thiotepa and escalating doses of mitoxantrone with autologous stem cell rescue in patients with refractory malignancies.
Journal: Bone marrow transplantation 19901201
Title: Phase I evaluation of thio-TEPA in combination with cisplatin for advanced gynecologic malignancies.
Journal: Gynecologic oncology 19901101
Title: Severe polyneuropathy and motor loss after intrathecal thiotepa combination chemotherapy: description of two cases.
Journal: Anti-cancer drugs 19901001
Title: Biotransformation of N,N',N''-triethylenethiophosphoramide: oxidative desulfuration to yield N,N',N''-triethylenephosphoramide associated with suicide inactivation of a phenobarbital-inducible hepatic P-450 monooxygenase.
Journal: Cancer research 19900201
Title: Nephrogenic adenoma in a patient with chronic renal failure associated with intravesical treatment with thiotepa.
Journal: European urology 19900101
Title: Mitomycin for patients who have failed on thiotepa. The National Bladder Cancer Group.
Journal: Urology 19851001
Title: Systemic influence of intravesical chemotherapy with verapamil.
Journal: Urological research 19850101
Title: Mitomycin C intravesical therapy in noninvasive bladder cancer after failure on thiotepa.
Journal: Cancer 19840301
Title: [Arsenic trioxide inhibition of the thiophosphamide induction of mutations in mouse germ and somatic cells].
Journal: Genetika 19840201
Title: Single and sequential combination intravesical chemotherapy of murine bladder cancer.
Journal: Urology 19820201
Title: The morphologic effects of mitomycin C in mammalian urinary bladder.
Journal: Cancer 19810601
Title: Hematologic effects of intravesicular thiotepa therapy for bladder carcinoma.
Journal: JAMA 19801107
Title: Intravesical thio-tepa: a study of 3H-thymidine uptake in normal urothelium and FANFT-induced tumors in rats.
Journal: Investigative urology 19790501
Title: Prophylaxis of bladder tumor implantation. Intravesical and systemic chemotherapy.
Journal: Urology 19760101
Title: The prophylactic use of thio-tepa and urokinase in transitional cell carcinoma of the bladder: a preliminary report.
Journal: The Journal of urology 19750901
Title: [Spontaneously cured pancytopenia due to intravesical thio-tepa, apropos of one case].
Journal: Journal d'urologie et de nephrologie 19731201
Title: [Fatal bone marrow aplasia due to endovesical thio-tepa].
Journal: Journal d'urologie et de nephrologie 19731201
Title: Renal failure associated with the use of thio-tepa.
Journal: The Journal of urology 19731101
Title: Prolonged apnea after succinylcholine in a case treated with cytostatics for cancer.
Journal: Anesthesia and analgesia 19720101
Title: Severe pancytopenia associated with the use of intravesical thio-TEPA.
Journal: The Journal of urology 19671001
Title: Pancytopenia and generalized sepsis following treatment of cancer of the bladder with instillations of triethylene thiophosphoramide.
Journal: The Journal of urology 19670301
Title: Qualitative defects of pseudocholinesterase activity.
Journal: Anaesthesia 19670101
Title: Hagen B, et al. Metabolism and alkylating activity of thio-TEPA in rat liver slice incubation. Cancer Chemother Pharmacol. 1991;28(6):441-7.
Title: Down JD, et al. Thiotepa improves allogeneic bone marrow engraftment without enhancing stem cell depletion in irradiated mice. Bone Marrow Transplant. 1998 Feb;21(4):327-30.
