Title: Hepatoprotective effects of diosmin and/or sildenafil against cholestatic liver cirrhosis: The role of Keap-1/Nrf-2 and P(38)-MAPK/NF-κB/iNOS signaling pathway.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20181001
Title: Diosmin induces genotoxicity and apoptosis in DU145 prostate cancer cell line.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20150401
Title: Diosmin abrogates chemically induced hepatocarcinogenesis via alleviation of oxidative stress, hyperproliferative and inflammatory markers in murine model.
Journal: Toxicology letters 20130718
Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Journal: Bioorganic & medicinal chemistry 20121115
Title: Diosmin protects rat retina from ischemia/reperfusion injury.
Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20121001
Title: The effects of doxycycline and micronized purified flavonoid fraction on human vein wall remodeling are not hypoxia-inducible factor pathway-dependent.
Journal: Journal of vascular surgery 20121001
Title: Chemical fingerprinting by RP-RRLC-DAD and principal component analysis of Ziziphora clinopodioides from different locations.
Journal: Natural product communications 20120901
Title: Phlebotonics for haemorrhoids.
Journal: The Cochrane database of systematic reviews 20120815
Title: Meta-analysis of the impact of the principal venoactive drugs agents on malleolar venous edema.
Journal: International angiology : a journal of the International Union of Angiology 20120801
Title: PP2A mediates diosmin p53 activation to block HA22T cell proliferation and tumor growth in xenografted nude mice through PI3K-Akt-MDM2 signaling suppression.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120501
Title: [Chemical constituents contained in seeds of Notopterygium franchetii].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120401
Title: Diosmin, a bioflavonoid reverses alterations in blood pressure, nitric oxide, lipid peroxides and antioxidant status in DOCA-salt induced hypertensive rats.
Journal: European journal of pharmacology 20120315
Title: Pharmacologic and compression therapies for postthrombotic syndrome: a systematic review of randomized controlled trials.
Journal: Chest 20120201
Title: Ameliorative effect of diosmin, a citrus flavonoid against streptozotocin-nicotinamide generated oxidative stress induced diabetic rats.
Journal: Chemico-biological interactions 20120105
Title: Cancer chemoprevention by citrus pulp and juices containing high amounts of β-cryptoxanthin and hesperidin.
Journal: Journal of biomedicine & biotechnology 20120101
Title: Screening of anti-dengue activity in methanolic extracts of medicinal plants.
Journal: BMC complementary and alternative medicine 20120101
Title: Centella asiatica Extract Improves Behavioral Deficits in a Mouse Model of Alzheimer's Disease: Investigation of a Possible Mechanism of Action.
Journal: International journal of Alzheimer's disease 20120101
Title: Secondary Metabolites from Plants Inhibiting ABC Transporters and Reversing Resistance of Cancer Cells and Microbes to Cytotoxic and Antimicrobial Agents.
Journal: Frontiers in microbiology 20120101
Title: Morphologic and pharmacological investigations in the epicatechin gastroprotective effect.
Journal: Evidence-based complementary and alternative medicine : eCAM 20120101
Title: Characteristics and clinical managements of chronic skin ulcers based on traditional chinese medicine.
Journal: Evidence-based complementary and alternative medicine : eCAM 20120101
Title: [Micronized purified flavonoid fraction in treatment of pelvic varicose veins].
Journal: Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20120101
Title: [On advisability of perioperative phleboprotection in endovascular treatment of lower in varicose disease: first initial results of the decision study].
Journal: Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20120101
Title: A comprehensive strategy to discover inhibitors of the translesion synthesis DNA polymerase κ.
Journal: PloS one 20120101
Title: Screening medicinal plants for the detection of novel antimalarial products applying the inhibition of β-hematin formation.
Journal: Journal of pharmaceutical and biomedical analysis 20111215
Title: Toxicological aspects of the use of phenolic compounds in disease prevention.
Journal: Interdisciplinary toxicology 20111201
Title: HPLC determination of hesperidin, diosmin and eriocitrin in Iranian lime juice using polyamide as an adsorbent for solid phase extraction.
Journal: Journal of pharmaceutical and biomedical analysis 20110910
Title: Protective effect of diosmin on LPS-induced apoptosis in PC12 cells and inhibition of TNF-α expression.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20110801
Title: Ca(2+)-dependent contraction by the saponoside escin in rat vena cava: implications in venotonic treatment of varicose veins.
Journal: Journal of vascular surgery 20110801
Title: Chemical genoprotection: reducing biological damage to as low as reasonably achievable levels.
Journal: Dento maxillo facial radiology 20110701
Title: Spontaneous intraventricular hemorrhage associated with prolonged diosmin therapy.
Journal: Neurocritical care 20110601
Title: Clinical effectiveness of a highly standardized and bioavailable mixture of flavonoids and triterpenes in the management of acute hemorroidal crisis.
Journal: Acta bio-medica : Atenei Parmensis 20110401
Title: How we can improve patients' comfort after Milligan-Morgan open haemorrhoidectomy.
Journal: World journal of gastroenterology 20110321
Title: Are venotonic drugs effective for decreasing acute posttraumatic oedema following ankle sprain? A prospective randomized clinical trial.
Journal: Archives of orthopaedic and trauma surgery 20110301
Title: Intestinal Anti-Inflammatory Activity of Baccharis dracunculifolia in the Trinitrobenzenesulphonic Acid Model of Rat Colitis.
Journal: Evidence-based complementary and alternative medicine : eCAM 20110101
Title: Pharmacological treatment of primary chronic venous disease: rationale, results and unanswered questions.
Journal: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20110101
Title: The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease.
Journal: International journal of molecular sciences 20110101
Title: Oral carcinogenesis and oral cancer chemoprevention: a review.
Journal: Pathology research international 20110101
Title: The effect of a flavonoid fractions diosmin + hesperidin on radiation-induced acute proctitis in a rat model.
Journal: Journal of cancer research and therapeutics 20110101
Title: Understanding carcinogenesis for fighting oral cancer.
Journal: Journal of oncology 20110101
Title: Antioxidant therapy: current status and future prospects.
Journal: Current medicinal chemistry 20110101
Title: Identification of novel functional inhibitors of acid sphingomyelinase.
Journal: PloS one 20110101
Title: Oxidative DNA Damage in Blood of CVD Patients Taking Detralex.
Journal: The open cardiovascular medicine journal 20110101
Title: Pathobiology and chemoprevention of bladder cancer.
Journal: Journal of oncology 20110101
Title: Diosmin ameliorates intestinal injury induced by hepatic ischemia reperfusion in rats.
Journal: Bratislavske lekarske listy 20110101
Title: Flavonoids: A versatile source of anticancer drugs.
Journal: Pharmacognosy reviews 20110101
Title: [Results of a multicentre clinical trial studying efficacy and safety of Vasocet in patients with varicose disease and chronic venous insufficiency].
Journal: Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20110101
Title: Experimental comparative study of the efficacy and side effects of Cissus quadrangularis L. (Vitaceae) to Daflon (Servier) and placebo in the treatment of acute hemorrhoids.
Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20101201
Title: Bioactive phenolics and antioxidant propensity of flavedo extracts of Mauritian citrus fruits: potential prophylactic ingredients for functional foods application.
Journal: Toxicology 20101128
Title: Flavonoid combinations cause synergistic inhibition of proinflammatory mediator secretion from lipopolysaccharide-induced RAW 264.7 cells.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20100901
Title: Antihyperglycemic effect of diosmin on hepatic key enzymes of carbohydrate metabolism in streptozotocin-nicotinamide-induced diabetic rats.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20100901
Title: Agenesis of the renal segment of inferior vena cava associated with venous stasis.
Journal: International angiology : a journal of the International Union of Angiology 20100801
Title: Dietary bioflavonoids inhibit Escherichia coli ATP synthase in a differential manner.
Journal: International journal of biological macromolecules 20100601
Title: Simultaneous determination of diosmin and diosmetin in human plasma by ion trap liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry: Application to a clinical pharmacokinetic study.
Journal: Journal of pharmaceutical and biomedical analysis 20100311
Title: Simultaneous determination of flavonoids and phenylethanoids in the flowers of Verbascum densiflorum and V. phlomoides by high-performance liquid chromatography.
Journal: Phytochemical analysis : PCA 20100101
Title: Micronized purified flavonoid fraction in pretreating CABG patients.
Journal: Texas Heart Institute journal 20100101
Title: [Monitoring the quality of life in patients with varicose disease of the lower extremities in the use of venarus].
Journal: Khirurgiia 20100101
Title: Gene-environment interaction research and transgenic mouse models of Alzheimer's disease.
Journal: International journal of Alzheimer's disease 20100101
Title: [Conservative treatment of patients with varicose esophagus veins cirrhosis].
Journal: Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20100101
Title: Flavonoids, a prenatal prophylaxis via targeting JAK2/STAT3 signaling to oppose IL-6/MIA associated autism.
Journal: Journal of neuroimmunology 20091210
Title: Radioprotective effects of Daflon against genotoxicity induced by gamma irradiation in human cultured lymphocytes.
Journal: Environmental and molecular mutagenesis 20091201
Title: Treatment of rat adjuvant arthritis with flavonoid (Detralex), methotrexate, and their combination.
Journal: Annals of the New York Academy of Sciences 20090901
Title: Cytotoxic activity of flavonoids from the flowers of Chrysanthemum morifolium on human colon cancer Colon205 cells.
Journal: Journal of Asian natural products research 20090901
Title: Vascular perfusion abnormalities in infants with spinal muscular atrophy.
Journal: The Journal of pediatrics 20090801
Title: Pharmacological agents in the treatment of venous disease: an update of the available evidence.
Journal: Current vascular pharmacology 20090701
Title: Synergistic effect of diosmin and interferon-alpha on metastatic pulmonary melanoma.
Journal: Cancer biotherapy & radiopharmaceuticals 20090601
Title: Flavonoid-mediated presenilin-1 phosphorylation reduces Alzheimer's disease beta-amyloid production.
Journal: Journal of cellular and molecular medicine 20090301
Title: The phytochemical analysis and antioxidant activity assessment of orange peel (Citrus sinensis) cultivated in Greece-Crete indicates a new commercial source of hesperidin.
Journal: Biomedical chromatography : BMC 20090301
Title: Simultaneous determination of the flavonoid aglycones diosmetin and hesperetin in human plasma and urine by a validated GC/MS method: in vivo metabolic reduction of diosmetin to hesperetin.
Journal: Biomedical chromatography : BMC 20090201
Title: Antihepatotoxic activity and chemical constituents of Buddleja asiatica Lour.
Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20090101
Title: Anti-collagenase, anti-elastase and anti-oxidant activities of extracts from 21 plants.
Journal: BMC complementary and alternative medicine 20090101
Title: [Drug-mediated correction of negative phlebotropic effects of hormone replacement therapy in women].
Journal: Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20090101
Title: [Application of Phlebodia 600 during the early postoperative period after gynecological surgeries with lymph node dissection, as well as application in the treatment of lymphedema during the late postoperative period].
Journal: Akusherstvo i ginekologiia 20090101
Title: Lemon Polyphenols Suppress Diet-induced Obesity by Up-Regulation of mRNA Levels of the Enzymes Involved in beta-Oxidation in Mouse White Adipose Tissue.
Journal: Journal of clinical biochemistry and nutrition 20081101
Title: Update on uses and properties of citrus flavonoids: new findings in anticancer, cardiovascular, and anti-inflammatory activity.
Journal: Journal of agricultural and food chemistry 20080813
Title: Effects of calcium dobesilate and diosmin-hesperidin on apoptosis of venous wall in primary varicose veins.
Journal: VASA. Zeitschrift fur Gefasskrankheiten 20080801
Title: Two-dimensional liquid chromatography coupled with mass spectrometry for the analysis of Lobelia chinensis Lour. using an ESI/APCI multimode ion source.
Journal: Journal of separation science 20080701
Title: Effects of purified micronized flavonoid fraction (Detralex) on prophylactic treatment of adjuvant arthritis with methotrexate in rats.
Journal: The Israel Medical Association journal : IMAJ 20080501
Title: Prediction of intestinal absorption and metabolism of pharmacologically active flavones and flavanones.
Journal: Bioorganic & medicinal chemistry 20080401
Title: Different flavonoids present in the micronized purified flavonoid fraction (Daflon 500 mg) contribute to its anti-hyperpermeability effect in the hamster cheek pouch microcirculation.
Journal: International angiology : a journal of the International Union of Angiology 20080201
Title: Identification of small molecule inhibitors of Pseudomonas aeruginosa exoenzyme S using a yeast phenotypic screen.
Journal: PLoS genetics 20080201
Title: Mechanisms in experimental venous valve failure and their modification by Daflon 500 mg.
Journal: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20080101
Title: [Certain aspects of pathogenesis of hemorheological and trophic disturbances and their pharmacological correction in patients with chronic venous insufficiency].
Journal: Vestnik khirurgii imeni I. I. Grekova 20080101
Title: [Use of phlebodia in pregnant women with feto-placental insufficiency (preeclampsia)].
Journal: Akusherstvo i ginekologiia 20080101
Title: Inflammaging as a prodrome to Alzheimer's disease.
Journal: Journal of neuroinflammation 20080101
Title: [The effect of oral contraceptives on the orthostatic diameter of lower limb major veins and its correction].
Journal: Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20080101
Title: [Using phlebodia in pregnant women during preterm delivery].
Journal: Akusherstvo i ginekologiia 20080101
Title: Medicamentous treatment of chronic venous insufficiency using semisynthetic diosmin--a prospective study.
Journal: Acta chirurgica Iugoslavica 20080101
Title: Influence of some bioflavonoids on the transport of nitrendipine.
Journal: Drug metabolism and drug interactions 20080101
Title: Influence of diosmin pretreatment on the pharmacokinetics of chlorzoxazone in healthy male volunteers.
Journal: Drug metabolism and drug interactions 20080101
Title: [Edema as a measure for severity of chronic venous insufficiency and efficacy of its treatment].
Journal: Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20080101
Title: [Combined therapy of lower limb variceal disease].
Journal: Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20080101
Title: [The 9th Annual Meeting of the European Venous Forum].
Journal: Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20080101
Title: [Immunological aspects of aphthous stomatitis].
Journal: Georgian medical news 20071001
Title: Effects of diosmin, a flavonoid glycoside in citrus fruits, on P-glycoprotein-mediated drug efflux in human intestinal Caco-2 cells.
Journal: Journal of agricultural and food chemistry 20070905
Title: Analgesic, anti-inflammatory and venotonic effects of Cissus quadrangularis Linn.
Journal: Journal of ethnopharmacology 20070321
Title: The effect of citrus flavonoids on the redox state of alimentary-induced fatty liver in rats.
Journal: Natural product research 20070301
Title: [Studies on pharmacokinetics of diosmin in rats].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070301
Title: Effects of micronized purified flavonoid fraction (Daflon) on pelvic pain in women with laparoscopically diagnosed pelvic congestion syndrome: a randomized crossover trial.
Journal: Clinical and experimental obstetrics & gynecology 20070101
Title: [Congenital anomalies of the inferior vena cava: diagnosis and medical treatment].
Journal: Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20070101
Title: Bioavailability of diclofenac sodium after pretreatment with diosmin in healthy volunteers.
Journal: Drug metabolism and drug interactions 20070101
Title: Surgical correction of varicose vein disease under micronized diosmin protection (results of the Russian multicenter controlled trial DEFANS).
Journal: Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20070101
Title: Screening of various phenolic acids and flavonoid derivatives for their anticholinesterase potential.
Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101
Title: [Results of administering Phlebodia 600 in fertile women with orthostasis-dependent phlebopathy].
Journal: Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20070101
Title: In vivo and in vitro assessment of human saphenous vein wall changes.
Journal: The open cardiovascular medicine journal 20070101
Title: Toxicological aspects of flavonoid interaction with biomacromolecules.
Journal: Neuro endocrinology letters 20061201
Title: Effects of citrus flavonoids on redox homeostasis of toxin-injured liver in rat.
Journal: Acta biologica Hungarica 20061201
Title: Possible regulation of venous outflow from deep brain structures.
Journal: Neuroscience and behavioral physiology 20061001
Title: Determination of trace levels of diosmin in a pharmaceutical preparation by adsorptive stripping voltammetry at a glassy carbon electrode.
Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20061001
Title: Central nervous system depressant action of flavonoid glycosides.
Journal: European journal of pharmacology 20060613
Title: The impact of micronized purified flavonoid fraction on the treatment of acute haemorrhoidal episodes.
Journal: Current medical research and opinion 20060601
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Comparison of Pycnogenol and Daflon in treating chronic venous insufficiency: a prospective, controlled study.
Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20060401
Title: Venoruton vs Daflon: evaluation of effects on quality of life in chronic venous insufficiency.
Journal: Angiology 20060101
Title: [Risk factors of chronic venous insufficiency of the lower extremities and possibilities of its medication in therapeutic practice].
Journal: Terapevticheskii arkhiv 20060101
Title: The effect of purified micronized flavonoid fraction on the healing of anastomoses in the colon in rats.
Journal: Surgery today 20060101
Title: [Semisynthetic Diosmin (Phlebodia 600) for therapy of lower limb chronic venous insufficiency].
Journal: Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20060101
Title: Micronized diosmin (Detralex) for vein-related trophic ulcers: European experience.
Journal: Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20060101
Title: The effect of the flavonoid diosmin, grape seed extract and red wine on the pulmonary metastatic B16F10 melanoma.
Journal: Histology and histopathology 20051001
Title: Re: Meshikhes A-W. N. Daflon for haemorrhoids: a prospective, multi-centre observational study. Surg JR Coll Surg Edinb Irel 2004;2(6): 355-38.
Journal: The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland 20051001
Title: Treatment of metastatic melanoma B16F10 by the flavonoids tangeretin, rutin, and diosmin.
Journal: Journal of agricultural and food chemistry 20050824
Title: Venous leg ulcer: a meta-analysis of adjunctive therapy with micronized purified flavonoid fraction.
Journal: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20050801
Title: Flavonoid glycosides inhibit oral cancer cell proliferation--role of cellular uptake and hydrolysis to the aglycones.
Journal: The Journal of pharmacy and pharmacology 20050801
Title: Flavonoids to reduce bleeding and pain after stapled hemorrhoidopexy: a randomized controlled trial.
Journal: Wiener klinische Wochenschrift 20050801
Title: [Analysis of surgical procedures on the vena saphena magna in the Czech Republic and an effect of Detralex during its stripping].
Journal: Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti 20050801
Title: [Butcher's Broom, in the treatment of venous insufficiency].
Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20050801
Title: Phlebotonics for venous insufficiency.
Journal: The Cochrane database of systematic reviews 20050720
Title: Determination of flavonoids in citrus juices by micro-HPLC-ESI/MS.
Journal: Journal of separation science 20050701
Title: Treatment of abnormal uterine bleeding with micronized flavonoids.
Journal: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20050501
Title: Venous ulcers: pathophysiology and treatment options.
Journal: Ostomy/wound management 20050501
Title: Micronized purified flavonoid fraction (MPFF): a review of its pharmacological effects, therapeutic efficacy and benefits in the management of chronic venous insufficiency.
Journal: Current vascular pharmacology 20050101
Title: HR, 0-(beta-hydroxyethyl)-rutosides, in comparison with diosmin+hesperidin in chronic venous insufficiency and venous microangiopathy: an independent, prospective, comparative registry study.
Journal: Angiology 20050101
Title: Hesperidin, a citrus bioflavonoid, decreases the oxidative stress produced by carbon tetrachloride in rat liver and kidney.
Journal: BMC pharmacology 20050101
Title: [Possibility of the regulation of venous outflow from deep brain structures].
Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20050101
Title: [PHLEBODIA (diosmine): a role in the management of bleeding nonprolapsed hemorrhoids].
Journal: Acta chirurgica Iugoslavica 20050101
Title: Chronic venous disease, inflammation, and Daflon 500 mg.
Journal: Angiology 20050101
Title: Chronic venous insufficiency and the therapeutic effects of Daflon 500 mg.
Journal: Angiology 20050101
Title: Daflon 500 mg: symptoms and edema clinical update.
Journal: Angiology 20050101
Title: Daflon 500 mg and venous leg ulcer: new results from a meta-analysis.
Journal: Angiology 20050101
Title: Antiradical and anti-H2O2 properties of polyphenolic compounds from an aqueous peppermint extract.
Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20050101
Title: [Derivatives of semi-synthetic diosmine in the treatment of patients with chronic venous insufficiency. The results of a prospective study--using phlebodia 600].
Journal: Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20050101
Title: A validated HPLC determination of the flavone aglycone diosmetin in human plasma.
Journal: Biomedical chromatography : BMC 20041201
Title: Daflon for haemorrhoids: a prospective, multi-centre observational study.
Journal: The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland 20041201
Title: Semisynthesis of linarin, acacetin, and 6-iodoapigenin derivatives from diosmin.
Journal: Journal of natural products 20040901
Title: Monograph. Diosmin.
Journal: Alternative medicine review : a journal of clinical therapeutic 20040901
Title: Flavonoid distribution during the development of leaves, flowers, stems, and roots of Rosmarinus officinalis. postulation of a biosynthetic pathway.
Journal: Journal of agricultural and food chemistry 20040811
Title: [The flavonoids effect against vinblastine, cyclophosphamide and paracetamol toxicity by inhibition of lipid-peroxydation and increasing liver glutathione concentration].
Journal: Pathologie-biologie 20040701
Title: Micronization enhances the protective effect of purified flavonoid fraction against postischaemic microvascular injury in the hamster cheek pouch.
Journal: Clinical and experimental pharmacology & physiology 20040301
Title: Effect of the rootstock and interstock grafted in lemon tree (Citrus limon (L.) Burm.) on the flavonoid content of lemon juice.
Journal: Journal of agricultural and food chemistry 20040128
Title: Study on the influence of silymarin pretreatment on metabolism and disposition of metronidazole.
Journal: Arzneimittel-Forschung 20040101
Title: Benzo-pyrones for reducing and controlling lymphoedema of the limbs.
Journal: The Cochrane database of systematic reviews 20040101
Title: [The principles of action and use of phlebotropic agents].
Journal: Klinicheskaia meditsina 20040101
Title: The effect of diosmin hesperidin on intestinal ischaemia--reperfusion injury.
Journal: Acta chirurgica Belgica 20040101
Title: A new flavonoid derivative, dosmalfate, attenuates the development of dextran sulphate sodium-induced colitis in mice.
Journal: International immunopharmacology 20031201
Title: Flavonoids as aryl hydrocarbon receptor agonists/antagonists: effects of structure and cell context.
Journal: Environmental health perspectives 20031201
Title: Effects of selected flavonoids and caffeic acid derivatives on hypoxanthine-xanthine oxidase-induced toxicity in cultivated human cells.
Journal: Planta medica 20031201
Title: Simultaneous reversed-phase high-performance liquid chromatographic method for the determination of diosmin, hesperidin and naringin in different citrus fruit juices and pharmaceutical formulations.
Journal: Journal of pharmaceutical and biomedical analysis 20030919
Title: Effects of Daflon on oxidative stress induced by hindlimb ischemia/reperfusion.
Journal: Pharmacological research 20030701
Title: Flavonoids detection by HPLC-DAD-MS-MS in lemon juices from Sicilian cultivars.
Journal: Journal of agricultural and food chemistry 20030604
Title: Flavonoid treatment in patients with healed venous ulcer: flow cytometry analysis suggests increased CD11b expression on neutrophil granulocytes in the circulation.
Journal: Vascular medicine (London, England) 20030501
Title: Diosmin pretreatment affects bioavailability of metronidazole.
Journal: European journal of clinical pharmacology 20030401
Title: Efficacy of a 6-month treatment with Daflon 500 mg in patients with venous leg ulcers associated with chronic venous insufficiency.
Journal: International angiology : a journal of the International Union of Angiology 20030301
Title: Effects of dosmalfate, a new cytoprotective agent, on acute and chronic trinitrobenzene sulphonic acid-induced colitis in rats.
Journal: European journal of pharmacology 20030124
Title: Micronised purified flavonoid fraction: a review of its use in chronic venous insufficiency, venous ulcers and haemorrhoids.
Journal: Drugs 20030101
Title: [The theory of lymphangion and current approaches to the pathogenesis, diagnosis and treatment of lymphedema of the lower extremities].
Journal: Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20030101
Title: The social and economic burden of venous leg ulcers: focus on the role of micronized purified flavonoid fraction adjuvant therapy.
Journal: American journal of clinical dermatology 20030101
Title: [Efficacy and safety of treatment with methotrexate, leflunomide, detralex, and their combination of patients with rheumatoid arthritis].
Journal: Likars'ka sprava 20030101
Title: From symptoms to leg edema: efficacy of Daflon 500 mg.
Journal: Angiology 20030101
Title: From skin disorders to venous leg ulcers: pathophysiology and efficacy of Daflon 500 mg in ulcer healing.
Journal: Angiology 20030101
Title: [Microcirculation end effect of detralex in patients with chronic venous insufficiency of the lower extremities].
Journal: Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20030101
Title: Efficacy of Daflon in the treatment of hemorrhoids.
Journal: Saudi medical journal 20021201
Title: Further investigation of the modifying effect of various chemopreventive agents on apoptosis and cell proliferation in human colon cancer cells.
Journal: Journal of cancer research and clinical oncology 20021001
Title: HR (Venoruton1000, Paroven, 0-[beta-hydroxyethyl]-rutosides) vs. Daflon 500 in chronic venous disease and microangiopathy: an independent prospective, controlled, randomized trial.
Journal: Journal of cardiovascular pharmacology and therapeutics 20020701
Title: Antiallergic effect of flavonoid glycosides obtained from Mentha piperita L.
Journal: Biological & pharmaceutical bulletin 20020201
Title: A randomised controlled trial of micronised purified flavonoid fraction vs placebo in patients with chronic venous disease.
Journal: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20020101
Title: Comparison of the absorption of micronized (Daflon 500 mg) and nonmicronized 14C-diosmin tablets after oral administration to healthy volunteers by accelerator mass spectrometry and liquid scintillation counting.
Journal: Journal of pharmaceutical sciences 20020101
Title: Chronic venous insufficiency: worldwide results of the RELIEF study. Reflux assEssment and quaLity of lIfe improvEment with micronized Flavonoids.
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Title: Anti-inflammatory actions of a micronized, purified flavonoid fraction in ischemia/reperfusion.
Journal: Advances in experimental medicine and biology 20020101
Title: Effects of plant-derived phenols on rat liver cytochrome P450 2B1 activity.
Journal: Anticancer research 20020101
Title: Radioprotective effects in vivo of phenolics extracted from Olea europaea L. leaves against X-ray-induced chromosomal damage: comparative study versus several flavonoids and sulfur-containing compounds.
Journal: Journal of medicinal food 20020101
Title: Improved LC methods for the determination of diosmin and/or hesperidin in plant extracts and pharmaceutical formulations.
Journal: Journal of pharmaceutical and biomedical analysis 20011101
Title: Flavonoids with epidermal growth factor-receptor tyrosine kinase inhibitory activity stimulate PEPT1-mediated cefixime uptake into human intestinal epithelial cells.
Journal: The Journal of pharmacology and experimental therapeutics 20011001
Title: Therapeutic approach to chronic venous insufficiency and its complications: place of Daflon 500 mg.
Journal: Angiology 20010801
Title: Clinical benefits of Daflon 500 mg in the most severe stages of chronic venous insufficiency.
Journal: Angiology 20010801
Title: Selection of hybrids and edible citrus species with a high content in the diosmin functional compound. Modulating effect of plant growth regulators on contents.
Journal: Journal of agricultural and food chemistry 20010701
Title: [Lymphocytic colitis after ingestion of Rustacea flavonoid extract].
Journal: Presse medicale (Paris, France : 1983) 20010601
Title: [Effect of daflon on the transcapillary fluid exchange in hindlimbs of anesthesized Wistar rats].
Journal: Eksperimental'naia i klinicheskaia farmakologiia 20010101
Title: [Clinical practice guidelines for the treatment of hemorrhoid disease].
Journal: Gastroenterologie clinique et biologique 20010101
Title: Clinical and hemodynamic outcomes in patients with chronic venous insufficiency after oral micronized flavonoid therapy.
Journal: Vascular surgery 20010101
Title: Inhibition of HIV activation in latently infected cells by flavonoid compounds.
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Title: Fulminant hepatitis due to cyproterone acetate.
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