52286-74-5,MFCD00210511
Catalog No.:AA00D8M5

52286-74-5 | Ginsenoside rg2

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98% by HPLC
in stock  
$77.00   $54.00
- +
5mg
≥98%
in stock  
$273.00   $191.00
- +
20mg
in stock  
$325.00   $228.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00D8M5
Chemical Name:
Ginsenoside rg2
CAS Number:
52286-74-5
Molecular Formula:
C34H58O5
Molecular Weight:
546.8213
MDL Number:
MFCD00210511
SMILES:
CCC=CCCC(C1CCC2C1CCC1C2CC(C2C1(C)CCC(C2(C)C)O)OC1CCC(C(O1)CO)O)C
Properties
Computed Properties
 
Complexity:
1390  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
21  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
55  
Hydrogen Bond Acceptor Count:
13  
Hydrogen Bond Donor Count:
9  
Isotope Atom Count:
0  
Rotatable Bond Count:
9  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
3.2  

Literature

Title: Ginsenoside Rg2 protects PC12 cells against β-amyloid(25-35)-induced apoptosis via the phosphoinositide 3-kinase/Akt pathway.

Journal: Chemico-biological interactions 20170925

Title: Effects of ginsenosides on the expression of cytochrome P450s and transporters involved in cholesterol metabolism.

Journal: Journal of natural medicines 20140401

Title: Saponins can perturb biologic membranes and reduce the surface tension of aqueous solutions: a correlation?

Journal: Bioorganic & medicinal chemistry 20120501

Title: Protective effects of Rg2 on hypoxia-induced neuronal damage in hippocampal neurons.

Journal: Artificial cells, blood substitutes, and immobilization biotechnology 20120201

Title: Ginsenoside Rg2 induces orphan nuclear receptor SHP gene expression and inactivates GSK3β via AMP-activated protein kinase to inhibit hepatic glucose production in HepG2 cells.

Journal: Chemico-biological interactions 20120105

Title: A novel ginsenosidase from an Aspergillus strain hydrolyzing 6-O-multi-glycosides of protopanaxatriol-type ginsenosides, named ginsenosidase type IV.

Journal: Journal of microbiology and biotechnology 20111001

Title: Effects of ginsenoside Rg2 on the ultraviolet B-induced DNA damage responses in HaCaT cells.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20100701

Title: [Study on excretion of ginsenoside Rg2 in rats].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090501

Title: Panax ginseng ginsenoside-Rg2 protects memory impairment via anti-apoptosis in a rat model with vascular dementia.

Journal: Journal of ethnopharmacology 20080212

Title: [Effects of 3 genosides on bio-thermodynamic expression of splenic lymphocyte in mice].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20080101

Title: Microbial transformation of 20(S)-protopanaxatriol-type saponins by Absidia coerulea.

Journal: Journal of natural products 20070701

Title: Protective effects of ginsenoside Rg2 against glutamate-induced neurotoxicity in PC12 cells.

Journal: Journal of ethnopharmacology 20070522

Title: Simultaneous enantiomer determination of 20 (R)- and 20 (S)-ginsenoside-Rg2 in rat plasma after intravenous administration using HPLC method.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070501

Title: Effects of mRg2, a mixture of ginsenosides containing 60% Rg2, on the ultraviolet B-induced DNA repair synthesis and apoptosis in NIH3T3 cells.

Journal: International journal of toxicology 20070101

Title: Extraction of 20(S)-ginsenoside Rg2 from cultured Panax notoginseng cells in vitro stimulates human umbilical cord vein endothelial cell proliferation.

Journal: American journal of therapeutics 20060101

Title: [Effect of ginsenoside Rg2 on chemical myocardial ischemia in rats].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20031201

Title: Differential effect of bovine serum albumin on ginsenoside metabolite-induced inhibition of alpha3beta4 nicotinic acetylcholine receptor expressed in Xenopus oocytes.

Journal: Archives of pharmacal research 20031001

Title: Enzymatic preparation of ginsenosides Rg2, Rh1, and F1.

Journal: Chemical & pharmaceutical bulletin 20030401

Title: Enzymatic preparation of ginsenosides Rg2, Rh1, and F1 from protopanaxatriol-type ginseng saponin mixture.

Journal: Planta medica 20030301

Title: Effects of ginsenoside Rg2 on the 5-HT3A receptor-mediated ion current in Xenopus oocytes.

Journal: Molecules and cells 20030227

Title: Effects of ginsenoside Rg2 on human neuronal nicotinic acetylcholine receptors.

Journal: The Journal of pharmacology and experimental therapeutics 20020601

Title: Characterization of ginseng saponin ginsenoside-Rg(3) inhibition of catecholamine secretion in bovine adrenal chromaffin cells.

Journal: Biochemical pharmacology 20011001

Title: [Effect of Rg2 on hemodynamics of hemorrhagic shock and its antioxidation in dogs].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20010801

Title: Inhibition by ginsenosides Rb1 and Rg1 of cocaine-induced hyperactivity, conditioned place preference, and postsynaptic dopamine receptor supersensitivity in mice.

Journal: Pharmacology, biochemistry, and behavior 19990701

Title: Cho YS, et al. Ginsenoside rg2 inhibits lipopolysaccharide-induced adhesion molecule expression in human umbilical vein endothelial cell. Korean J Physiol Pharmacol. 2013 Apr;17(2):133-7.

Title: Li N, et al. A UPLC/MS-based metabolomics investigation of the protective effect of ginsenosides Rg1 and Rg2 in mice with Alzheimer's disease. J Ginseng Res. 2016 Jan;40(1):9-17.

Title: Cho YS, et al. Ginsenoside rg2 inhibits lipopolysaccharide-induced adhesion molecule expression in human umbilical vein endothelial cell. Korean J Physiol Pharmacol. 2013;17(2):133-137.

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SDS
Tags:52286-74-5 Molecular Formula|52286-74-5 MDL|52286-74-5 SMILES|52286-74-5 Ginsenoside rg2
Catalog No.: AA00D8M5
52286-74-5,MFCD00210511
52286-74-5 | Ginsenoside rg2
Pack Size: 1mg
Purity: 98% by HPLC
in stock
$77.00 $54.00
Pack Size: 5mg
Purity: ≥98%
in stock
$273.00 $191.00
Pack Size: 20mg
Purity:
in stock
$325.00 $228.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00D8M5
Chemical Name: Ginsenoside rg2
CAS Number: 52286-74-5
Molecular Formula: C34H58O5
Molecular Weight: 546.8213
MDL Number: MFCD00210511
SMILES: CCC=CCCC(C1CCC2C1CCC1C2CC(C2C1(C)CCC(C2(C)C)O)OC1CCC(C(O1)CO)O)C
Properties
Complexity: 1390  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 21  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 55  
Hydrogen Bond Acceptor Count: 13  
Hydrogen Bond Donor Count: 9  
Isotope Atom Count: 0  
Rotatable Bond Count: 9  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 3.2  
Literature fold

Title: Ginsenoside Rg2 protects PC12 cells against β-amyloid(25-35)-induced apoptosis via the phosphoinositide 3-kinase/Akt pathway.

Journal: Chemico-biological interactions20170925

Title: Effects of ginsenosides on the expression of cytochrome P450s and transporters involved in cholesterol metabolism.

Journal: Journal of natural medicines20140401

Title: Saponins can perturb biologic membranes and reduce the surface tension of aqueous solutions: a correlation?

Journal: Bioorganic & medicinal chemistry20120501

Title: Protective effects of Rg2 on hypoxia-induced neuronal damage in hippocampal neurons.

Journal: Artificial cells, blood substitutes, and immobilization biotechnology20120201

Title: Ginsenoside Rg2 induces orphan nuclear receptor SHP gene expression and inactivates GSK3β via AMP-activated protein kinase to inhibit hepatic glucose production in HepG2 cells.

Journal: Chemico-biological interactions20120105

Title: A novel ginsenosidase from an Aspergillus strain hydrolyzing 6-O-multi-glycosides of protopanaxatriol-type ginsenosides, named ginsenosidase type IV.

Journal: Journal of microbiology and biotechnology20111001

Title: Effects of ginsenoside Rg2 on the ultraviolet B-induced DNA damage responses in HaCaT cells.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20100701

Title: [Study on excretion of ginsenoside Rg2 in rats].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20090501

Title: Panax ginseng ginsenoside-Rg2 protects memory impairment via anti-apoptosis in a rat model with vascular dementia.

Journal: Journal of ethnopharmacology20080212

Title: [Effects of 3 genosides on bio-thermodynamic expression of splenic lymphocyte in mice].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine20080101

Title: Microbial transformation of 20(S)-protopanaxatriol-type saponins by Absidia coerulea.

Journal: Journal of natural products20070701

Title: Protective effects of ginsenoside Rg2 against glutamate-induced neurotoxicity in PC12 cells.

Journal: Journal of ethnopharmacology20070522

Title: Simultaneous enantiomer determination of 20 (R)- and 20 (S)-ginsenoside-Rg2 in rat plasma after intravenous administration using HPLC method.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20070501

Title: Effects of mRg2, a mixture of ginsenosides containing 60% Rg2, on the ultraviolet B-induced DNA repair synthesis and apoptosis in NIH3T3 cells.

Journal: International journal of toxicology20070101

Title: Extraction of 20(S)-ginsenoside Rg2 from cultured Panax notoginseng cells in vitro stimulates human umbilical cord vein endothelial cell proliferation.

Journal: American journal of therapeutics20060101

Title: [Effect of ginsenoside Rg2 on chemical myocardial ischemia in rats].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20031201

Title: Differential effect of bovine serum albumin on ginsenoside metabolite-induced inhibition of alpha3beta4 nicotinic acetylcholine receptor expressed in Xenopus oocytes.

Journal: Archives of pharmacal research20031001

Title: Enzymatic preparation of ginsenosides Rg2, Rh1, and F1.

Journal: Chemical & pharmaceutical bulletin20030401

Title: Enzymatic preparation of ginsenosides Rg2, Rh1, and F1 from protopanaxatriol-type ginseng saponin mixture.

Journal: Planta medica20030301

Title: Effects of ginsenoside Rg2 on the 5-HT3A receptor-mediated ion current in Xenopus oocytes.

Journal: Molecules and cells20030227

Title: Effects of ginsenoside Rg2 on human neuronal nicotinic acetylcholine receptors.

Journal: The Journal of pharmacology and experimental therapeutics20020601

Title: Characterization of ginseng saponin ginsenoside-Rg(3) inhibition of catecholamine secretion in bovine adrenal chromaffin cells.

Journal: Biochemical pharmacology20011001

Title: [Effect of Rg2 on hemodynamics of hemorrhagic shock and its antioxidation in dogs].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20010801

Title: Inhibition by ginsenosides Rb1 and Rg1 of cocaine-induced hyperactivity, conditioned place preference, and postsynaptic dopamine receptor supersensitivity in mice.

Journal: Pharmacology, biochemistry, and behavior19990701

Title: Cho YS, et al. Ginsenoside rg2 inhibits lipopolysaccharide-induced adhesion molecule expression in human umbilical vein endothelial cell. Korean J Physiol Pharmacol. 2013 Apr;17(2):133-7.

Title: Li N, et al. A UPLC/MS-based metabolomics investigation of the protective effect of ginsenosides Rg1 and Rg2 in mice with Alzheimer's disease. J Ginseng Res. 2016 Jan;40(1):9-17.

Title: Cho YS, et al. Ginsenoside rg2 inhibits lipopolysaccharide-induced adhesion molecule expression in human umbilical vein endothelial cell. Korean J Physiol Pharmacol. 2013;17(2):133-137.

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