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14197-60-5,MFCD06410950
Catalog No.:AA006WQ1

14197-60-5 | Ginsenoside rg3

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Purity
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5mg
95%
in stock  
$37.00   $26.00
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25mg
95%
in stock  
$99.00   $69.00
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100mg
95%
in stock  
$293.00   $205.00
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA006WQ1
Chemical Name:
Ginsenoside rg3
CAS Number:
14197-60-5
Molecular Formula:
C42H72O13
Molecular Weight:
785.0133
MDL Number:
MFCD06410950
SMILES:
OC[C@H]1O[C@@H](O[C@H]2CC[C@]3([C@H](C2(C)C)CC[C@@]2([C@@H]3C[C@@H](O)[C@H]3[C@@]2(C)CC[C@@H]3[C@](CCC=C(C)C)(O)C)C)C)[C@@H]([C@H]([C@@H]1O)O)O[C@@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O
Properties
Properties
 
Form:
Solid  
MP:
209-219°C  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
1370  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
20  
Heavy Atom Count:
55  
Hydrogen Bond Acceptor Count:
13  
Hydrogen Bond Donor Count:
9  
Rotatable Bond Count:
10  
XLogP3:
4  

Literature

Title: Ginsenoside F1 suppresses astrocytic senescence-associated secretory phenotype.

Journal: Chemico-biological interactions 20180301

Title: Ginsenosides Rg3 attenuates glucocorticoid-induced osteoporosis through regulating BMP-2/BMPR1A/Runx2 signaling pathway.

Journal: Chemico-biological interactions 20160825

Title: Ginsenoside Rg3 induces FUT4-mediated apoptosis in H. pylori CagA-treated gastric cancer cells by regulating SP1 and HSF1 expressions.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20160301

Title: Novel roles of ginsenoside Rg3 in apoptosis through downregulation of epidermal growth factor receptor.

Journal: Chemico-biological interactions 20150525

Title: Stereospecific effects of ginsenoside 20-Rg3 inhibits TGF-β1-induced epithelial-mesenchymal transition and suppresses lung cancer migration, invasion and anoikis resistance.

Journal: Toxicology 20140801

Title: YY162 prevents ADHD-like behavioral side effects and cytotoxicity induced by Aroclor1254 via interactive signaling between antioxidant potential, BDNF/TrkB, DAT and NET.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20140301

Title: Ginsenoside Re and Rd enhance the expression of cholinergic markers and neuronal differentiation in Neuro-2a cells.

Journal: Biological & pharmaceutical bulletin 20140101

Title: Chronic treatment with ginsenoside Rg3 induces Akt-dependent senescence in human glioma cells.

Journal: International journal of oncology 20121101

Title: Neuroprotective effect of 20(R)-ginsenoside Rg(3) against transient focal cerebral ischemia in rats.

Journal: Neuroscience letters 20120927

Title: Ginsenoside Rg3 inhibits endothelial progenitor cell differentiation through attenuation of VEGF-dependent Akt/eNOS signaling.

Journal: Phytotherapy research : PTR 20120901

Title: Conversion of protopanaxadiol type saponins to ginsenoside Rg3 by lemon.

Journal: Natural product communications 20120901

Title: Red ginseng and 20(S)-Rg3 control testosterone-induced prostate hyperplasia by deregulating androgen receptor signaling.

Journal: Journal of natural medicines 20120701

Title: Ginsenoside Rg3 enhances the chemosensitivity of tumors to cisplatin by reducing the basal level of nuclear factor erythroid 2-related factor 2-mediated heme oxygenase-1/NAD(P)H quinone oxidoreductase-1 and prevents normal tissue damage by scavenging cisplatin-induced intracellular reactive oxygen species.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120701

Title: Stereospecificity of ginsenoside Rg3 in promotion of the immune response to ovalbumin in mice.

Journal: International immunology 20120701

Title: Stereospecific antioxidant effects of ginsenoside Rg3 on oxidative stress induced by cyclophosphamide in mice.

Journal: Fitoterapia 20120601

Title: Ginsenoside Rg3 attenuates cell migration via inhibition of aquaporin 1 expression in PC-3M prostate cancer cells.

Journal: European journal of pharmacology 20120515

Title: Ginsenoside Rg3 attenuates tumor angiogenesis via inhibiting bioactivities of endothelial progenitor cells.

Journal: Cancer biology & therapy 20120501

Title: Stereoisomers ginsenosides-20(S)-Rg₃ and -20(R)-Rg₃ differentially induce angiogenesis through peroxisome proliferator-activated receptor-gamma.

Journal: Biochemical pharmacology 20120401

Title: Enzymatic biotransformation of ginsenoside Rb1 to 20(S)-Rg3 by recombinant β-glucosidase from Microbacterium esteraromaticum.

Journal: Applied microbiology and biotechnology 20120401

Title: Microbial transformation of ginsenoside Rg3 to ginsenoside Rh2 by Esteya vermicola CNU 120806.

Journal: World journal of microbiology & biotechnology 20120401

Title: Effects of ginseng rhizome and ginsenoside Ro on testosterone 5α-reductase and hair re-growth in testosterone-treated mice.

Journal: Phytotherapy research : PTR 20120101

Title: Cytoprotective effect of 20S-Rg3 on benzo[a]pyrene-induced DNA damage.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20120101

Title: Ginsenoside Rg3 reduces lipid accumulation with AMP-Activated Protein Kinase (AMPK) activation in HepG2 cells.

Journal: International journal of molecular sciences 20120101

Title: Transient receptor potential melastatin 7 channels are involved in ginsenoside Rg3-induced apoptosis in gastric cancer cells.

Journal: Basic & clinical pharmacology & toxicology 20111001

Title: Ginsenoside Rg3 inhibits CXCR4 expression and related migrations in a breast cancer cell line.

Journal: International journal of clinical oncology 20111001

Title: Ginsenoside Rg3 inhibit hepatocellular carcinoma growth via intrinsic apoptotic pathway.

Journal: World journal of gastroenterology 20110821

Title: Toxicity of a novel anti-tumor agent 20(S)-ginsenoside Rg3: a 26-week intramuscular repeated administration study in Beagle dogs.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110801

Title: Ginsenoside Rg(3) decelerates hERG K(+) channel deactivation through Ser631 residue interaction.

Journal: European journal of pharmacology 20110801

Title: Effect of ginsenosides Rg3 and Re on glucose transport in mature 3T3-L1 adipocytes.

Journal: Phytotherapy research : PTR 20110501

Title: Immunopotentiation and antitumor effects of a ginsenoside Rg₃-fortified red ginseng preparation in mice bearing H460 lung cancer cells.

Journal: Environmental toxicology and pharmacology 20110501

Title: [Effect of ginsenoside Rg3 on hepatic fibrosis in murine schistosomiasis japonica].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20110430

Title: Bioactive constituents from the roots of Panax japonicus var. major and development of a LC-MS/MS method for distinguishing between natural and artifactual compounds.

Journal: Journal of natural products 20110425

Title: Antidepressant-like effect of altered Korean red ginseng in mice.

Journal: Behavioral medicine (Washington, D.C.) 20110401

Title: Ginsenoside Rg3 enhances large conductance Ca2+-activated potassium channel currents: a role of Tyr360 residue.

Journal: Molecules and cells 20110227

Title: Ginsenoside Rh2 induces apoptosis and paraptosis-like cell death in colorectal cancer cells through activation of p53.

Journal: Cancer letters 20110227

Title: Ginsenoside Rg3 inhibits colorectal tumor growth through the down-regulation of Wnt/ß-catenin signaling.

Journal: International journal of oncology 20110201

Title: Effects of ginsenoside on large-conductance K(Ca) channels in human corporal smooth muscle cells.

Journal: International journal of impotence research 20110101

Title: Vascular smooth muscle dysfunction and remodeling induced by ginsenoside Rg3, a bioactive component of ginseng.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20101001

Title: [Inhibitory effect of ginsenoside Rg3 on the tube-like structure formation in human nasopharyngeal carcinoma HNE-1 cell line in vitro].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20101001

Title: Enzymatic preparation of 20(S, R)-protopanaxadiol by transformation of 20(S, R)-Rg3 from black ginseng.

Journal: Phytochemistry 20100901

Title: Ginsenoside Rg3 inhibits tumor necrosis factor-alpha-induced expression of cell adhesion molecules in human endothelial cells.

Journal: Die Pharmazie 20100901

Title: Determination of ginsenoside Rg3 in human plasma and urine by high performance liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100815

Title: Ginsenoside rb1 and rg3 attenuate glucocorticoid-induced neurotoxicity.

Journal: Cellular and molecular neurobiology 20100801

Title: Ginsenoside Rg3 activates human KCNQ1 K+ channel currents through interacting with the K318 and V319 residues: a role of KCNE1 subunit.

Journal: European journal of pharmacology 20100710

Title: Cytotoxicity and inhibition of DNA topoisomerase I of polyhydroxylated triterpenoids and triterpenoid glycosides.

Journal: Bioorganic & medicinal chemistry letters 20100501

Title: Combination of ginsenoside Rg3 with docetaxel enhances the susceptibility of prostate cancer cells via inhibition of NF-kappaB.

Journal: European journal of pharmacology 20100410

Title: Improving enzymatic production of ginsenoside Rh2 from Rg3 by using nonionic surfactant.

Journal: Applied biochemistry and biotechnology 20100201

Title: Gensenoside Rg3 inhibits hypoxia-induced VEGF expression in human cancer cells.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101

Title: The ginsenoside Rg3 has a stimulatory effect on insulin signaling in L6 myotubes.

Journal: Biochemical and biophysical research communications 20091106

Title: [Efficacy of Shenyi Capsule combined with gemcitabine plus cisplatin in treatment of advanced esophageal cancer: a randomized controlled trial].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20091101

Title: [The effects of ginsenosides Rg3 on the expressions of VEGF and KDR in human lung squamous cancer cells].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20091101

Title: Optimization of the enzymatic production of 20(S)-ginsenoside Rg(3) from white ginseng extract using response surface methodology.

Journal: New biotechnology 20091031

Title: [Ginsenoside Rg3 induces apoptosis of human lung squamous cell carcinoma SK-MES-1 cell line].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090901

Title: Mutations Leu427, Asn428, and Leu431 residues within transmembrane domain-I-segment 6 attenuate ginsenoside-mediated L-type Ca(2+) channel current inhibitions.

Journal: Biological & pharmaceutical bulletin 20090701

Title: Anxiolytic-like effects of ginsenosides Rg3 and Rh2 from red ginseng in the elevated plus-maze model.

Journal: Planta medica 20090601

Title: A role for Leu247 residue within transmembrane domain 2 in ginsenoside-mediated alpha7 nicotinic acetylcholine receptor regulation.

Journal: Molecules and cells 20090531

Title: Inhibition of NF-kappaB by ginsenoside Rg3 enhances the susceptibility of colon cancer cells to docetaxel.

Journal: Archives of pharmacal research 20090501

Title: [Effect of ginsenoside Rg3 on Pim-3 and Bad proteins in human pancreatic cancer cell line PANC-1].

Journal: Ai zheng = Aizheng = Chinese journal of cancer 20090501

Title: Proteomic analysis of the anti-cancer effect of 20S-ginsenoside Rg3 in human colon cancer cell lines.

Journal: Bioscience, biotechnology, and biochemistry 20090423

Title: 20(S)-ginsenoside Rg3, a neuroprotective agent, inhibits mitochondrial permeability transition pores in rat brain.

Journal: Phytotherapy research : PTR 20090401

Title: Generation and characterization of monoclonal antibody to ginsenoside rg3.

Journal: Biological & pharmaceutical bulletin 20090401

Title: The effects of ginsenoside Rg(3) on human Kv1.4 channel currents without the N-terminal rapid inactivation domain.

Journal: Biological & pharmaceutical bulletin 20090401

Title: Ginsenoside Rg3 promotes beta-amyloid peptide degradation by enhancing gene expression of neprilysin.

Journal: The Journal of pharmacy and pharmacology 20090301

Title: Antiobesity effect of ginsenoside Rg3 involves the AMPK and PPAR-gamma signal pathways.

Journal: Phytotherapy research : PTR 20090201

Title: [Effect of gensenoside Rg3 on apoptosis of Hep-2 and expression of HIF-1alha in human laryngeal cancer cell line under anoxic conditions].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090101

Title: Inhibitory effect of ginsenoside Rg3 combined with gemcitabine on angiogenesis and growth of lung cancer in mice.

Journal: BMC cancer 20090101

Title: The anti-fatigue effect of 20(R)-ginsenoside Rg3 in mice by intranasally administration.

Journal: Biological & pharmaceutical bulletin 20081101

Title: Research on the antitumor effect of ginsenoside Rg3 in B16 melanoma cells.

Journal: Melanoma research 20081001

Title: Antiangiogenic effect of capecitabine combined with ginsenoside Rg3 on breast cancer in mice.

Journal: Cancer biotherapy & radiopharmaceuticals 20081001

Title: Therapeutic potential of 20(S)-ginsenoside Rg(3) against streptozotocin-induced diabetic renal damage in rats.

Journal: European journal of pharmacology 20080904

Title: [Fungal biotransformation of ginsenoside Rg3].

Journal: Wei sheng wu xue bao = Acta microbiologica Sinica 20080901

Title: Inhibitory effect of ginsenoside Rg3 on ovarian cancer metastasis.

Journal: Chinese medical journal 20080805

Title: Metabonomics study on the effects of the ginsenoside Rg3 in a beta-cyclodextrin-based formulation on tumor-bearing rats by a fully automatic hydrophilic interaction/reversed-phase column-switching HPLC-ESI-MS approach.

Journal: Analytical chemistry 20080615

Title: Characterization of gene expression regulated by American ginseng and ginsenoside Rg3 in human colorectal cancer cells.

Journal: International journal of oncology 20080501

Title: Involvement of batrachotoxin binding sites in ginsenoside-mediated voltage-gated Na+ channel regulation.

Journal: Brain research 20080408

Title: 20(S)-ginsenoside Rg3 enhances glucose-stimulated insulin secretion and activates AMPK.

Journal: Biological & pharmaceutical bulletin 20080401

Title: Ginsenoside Rg3 inhibits human Kv1.4 channel currents by interacting with the Lys531 residue.

Journal: Molecular pharmacology 20080301

Title: Effect and mechanism of ginsenoside Rg3 on postoperative life span of patients with non-small cell lung cancer.

Journal: Chinese journal of integrative medicine 20080301

Title: Modifications of aliphatic side chain of 20(S)-ginsenoside RG3 cause an enhancement or loss of brain Na+ channel current inhibitions.

Journal: Biological & pharmaceutical bulletin 20080301

Title: [Raman spectroscopy study on the structure of ginsenoside Rg3].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20080301

Title: 20(S)-25-methoxyl-dammarane-3beta, 12beta, 20-triol, a novel natural product for prostate cancer therapy: activity in vitro and in vivo and mechanisms of action.

Journal: British journal of cancer 20080226

Title: Protective effects of ginsenoside Rg(3) against cyclophosphamide-induced DNA damage and cell apoptosis in mice.

Journal: Archives of toxicology 20080201

Title: Selective toxicity of ginsenoside Rg3 on multidrug resistant cells by membrane fluidity modulation.

Journal: Archives of pharmacal research 20080201

Title: Neuroprotective effects of ginseng saponins against L-type Ca2+ channel-mediated cell death in rat cortical neurons.

Journal: Biochemical and biophysical research communications 20080118

Title: Conversion of major ginsenoside Rb1 to 20(S)-ginsenoside Rg3 by Microbacterium sp. GS514.

Journal: Phytochemistry 20080101

Title: [Correlation of insulin-like growth factor-1 (IGF-1) to angiogenesis of breast cancer in IGF-1-deficient mice].

Journal: Ai zheng = Aizheng = Chinese journal of cancer 20071101

Title: Preventive effect of 20(S)-ginsenoside Rg3 against lipopolysaccharide-induced hepatic and renal injury in rats.

Journal: Free radical research 20071001

Title: Marked production of ginsenosides Rd, F2, Rg3, and compound K by enzymatic method.

Journal: Chemical & pharmaceutical bulletin 20071001

Title: Mutations of arginine 222 in pre-transmembrane domain I of mouse 5-HT(3A) receptor abolish 20(R)- but not 20(S)-ginsenoside Rg(3) inhibition of 5-HT-mediated ion currents.

Journal: Biological & pharmaceutical bulletin 20070901

Title: Panaxadiol glycosides that induce neuronal differentiation in neurosphere stem cells.

Journal: Journal of natural products 20070801

Title: [Inducement effect of ginsenoside Rg3 on apoptosis of human bladder transitional cell carcinoma cell line EJ].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070801

Title: Bifidus fermentation increases hypolipidemic and hypoglycemic effects of red ginseng.

Journal: Journal of microbiology and biotechnology 20070701

Title: Red American ginseng: ginsenoside constituents and antiproliferative activities of heat-processed Panax quinquefolius roots.

Journal: Planta medica 20070601

Title: Inhibitory effect of ginsenoside Rg3 combined with cyclophosphamide on growth and angiogenesis of ovarian cancer.

Journal: Chinese medical journal 20070405

Title: Neuroprotective effects of ginsenoside Rg3 against homocysteine-induced excitotoxicity in rat hippocampus.

Journal: Brain research 20070309

Title: Identification of ginsenoside interaction sites in 5-HT3A receptors.

Journal: Neuropharmacology 20070301

Title: [Effect of adjuvant chemotherapy of ginsenoside Rg3 combined with mitomycin C and tegafur in advanced gastric cancer].

Journal: Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20070101

Title: Inhibitory effects of Korean red ginseng and its genuine constituents ginsenosides Rg3, Rf, and Rh2 in mouse passive cutaneous anaphylaxis reaction and contact dermatitis models.

Journal: Biological & pharmaceutical bulletin 20060901

Title: The angiosuppressive effects of 20(R)- ginsenoside Rg3.

Journal: Biochemical pharmacology 20060814

Title: [Determination of ginsenoside Rd and its metabolites in rat urine by LC-MS].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20060801

Title: The antistress effect of ginseng total saponin and ginsenoside Rg3 and Rb1 evaluated by brain polyamine level under immobilization stress.

Journal: Pharmacological research 20060701

Title: Reductions in levels of the Alzheimer's amyloid beta peptide after oral administration of ginsenosides.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060601

Title: Ginsenosides Rg3 and Rh2 inhibit the activation of AP-1 and protein kinase A pathway in lipopolysaccharide/interferon-gamma-stimulated BV-2 microglial cells.

Journal: Planta medica 20060601

Title: 20(S)-ginsenoside Rh2, a newly identified active ingredient of ginseng, inhibits NMDA receptors in cultured rat hippocampal neurons.

Journal: European journal of pharmacology 20060424

Title: Antiangiogenic effect of low-dose cyclophosphamide combined with ginsenoside Rg3 on Lewis lung carcinoma.

Journal: Biochemical and biophysical research communications 20060414

Title: Stereospecific effects of ginsenoside Rg3 epimers on swine coronary artery contractions.

Journal: Biological & pharmaceutical bulletin 20060201

Title: [The effects of 20(R)-Rg3 on lung carcinoma A549 cell line and endogenous VEGF secreted by tumor cells].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20060101

Title: [Metabolite fingerprint and biomarkers identification of rat urine after dosed with ginsenoside Rg3 based on ultra high performance liquid chromatography/time-of-flight mass spectrometry (UPLC/TOF-MS)].

Journal: Se pu = Chinese journal of chromatography 20060101

Title: [Effects of ginsenoside Rg3 on the micro-lymphatic metastasis of colorectal neoplasms].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20051201

Title: Characteristics of ginsenoside Rg3-mediated brain Na+ current inhibition.

Journal: Molecular pharmacology 20051001

Title: Hepatoprotective effect of 20(S)-ginsenosides Rg3 and its metabolite 20(S)-ginsenoside Rh2 on tert-butyl hydroperoxide-induced liver injury.

Journal: Biological & pharmaceutical bulletin 20051001

Title: Potential effects of microglial activation induced by ginsenoside Rg3 in rat primary culture: enhancement of type A Macrophage Scavenger Receptor expression.

Journal: Archives of pharmacal research 20051001

Title: Evidence that the tertiary structure of 20(S)-ginsenoside Rg(3) with tight hydrophobic packing near the chiral center is important for Na(+) channel regulation.

Journal: Biochemical and biophysical research communications 20050812

Title: [Experimental study on anti-angiogenesis in mice with Lewis lung carcinoma by low-dose of cyclophosphamide combined with ginsenoside Rg3].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20050801

Title: Relaxation of canine corporal smooth muscle relaxation by ginsenoside saponin Rg3 is independent from eNOS activation.

Journal: Life sciences 20050520

Title: High performance liquid chromatographic-mass spectrometric determination of ginsenoside Rg3 and its metabolites in rat plasma using solid-phase extraction for pharmacokinetic studies.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050425

Title: [Effect of ginsenoside on the cellular proliferation, apoptosis and cell cycles in LC A549 and HUVEC 304 cell lines].

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20050401

Title: [The inhibition of 20(R)-ginsenoside Rg3 on the expressions of angiogenesis factors proteins in human lung adenocarcinoma cell line A549 and HUVEC304 cell].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050301

Title: [Anticarcinogenic effect of 20(R)-ginsenoside Rg3 on induced hepatocellular carcinoma in rats].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20050301

Title: Memory enhancing and neuroprotective effects of selected ginsenosides.

Journal: Archives of pharmacal research 20050301

Title: [Distribution and pharmacokinetics of 20S-ginsenoside Rg3 eyeointment in rabbit eye].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20050301

Title: A role for the carbohydrate portion of ginsenoside Rg3 in Na+ channel inhibition.

Journal: Molecules and cells 20050227

Title: In vivo rat metabolism and pharmacokinetic studies of ginsenoside Rg3.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050225

Title: Neuroprotective effect of 20(S)-ginsenoside Rg3 on cerebral ischemia in rats.

Journal: Neuroscience letters 20050210

Title: Liquid chromatography/tandem mass spectrometry for pharmacokinetic studies of 20(R)-ginsenoside Rg3 in dog.

Journal: Rapid communications in mass spectrometry : RCM 20050101

Title: [Experimental study on effect of chemotherapy combined ginsengnoside Rg3 in treating pulmonary carcinoma].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20050101

Title: Evaluation of chemopreventive action and antimutagenic effect of the standardized Panax ginseng extract, EFLA400, in Swiss albino mice.

Journal: Phytotherapy research : PTR 20050101

Title: Stereospecificity of ginsenoside Rg3 action on ion channels.

Journal: Molecules and cells 20041231

Title: Changes of [3H]MK-801, [3H]muscimol and [3H]flunitrazepam binding in rat brain by the prolonged ventricular infusion of transformed ginsenosides.

Journal: Neurochemical research 20041201

Title: [Inhibitory effect of ginsenoside-Rg3 on lung metastasis of mouse melanoma transfected with ribonuclease inhibitor].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20041201

Title: Ginsenoside Rg3 antagonizes NMDA receptors through a glycine modulatory site in rat cultured hippocampal neurons.

Journal: Biochemical and biophysical research communications 20041015

Title: Hematopoietic effect of ginsenoside Rg3 in ICR mouse primary cultures and its application to a biological response modifier.

Journal: Fitoterapia 20040601

Title: Effects of ginsenosides Rg3 and Rh2 on the proliferation of prostate cancer cells.

Journal: Archives of pharmacal research 20040401

Title: [Progress of the study on effective integredients from Chinese herbal medicine in anti-tumor metastasis].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040201

Title: Ginsenoside Rg3 inhibits phenylephrine-induced vascular contraction through induction of nitric oxide synthase.

Journal: British journal of pharmacology 20031001

Title: [Effect of ginsenoside Rg3 on the progression of orthotopically xenotransplanted human breast cancer in nude mice and its mechanism].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20030701

Title: [Advances in the study of tumor angiogenesis and anti-angiogenic Chinese herbal drugs].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20030501

Title: Reversal of P-glycoprotein-mediated multidrug resistance by ginsenoside Rg(3).

Journal: Biochemical pharmacology 20030101

Title: Inhibitory effects of the ginsenoside Rg3 on phorbol ester-induced cyclooxygenase-2 expression, NF-kappaB activation and tumor promotion.

Journal: Mutation research 20030101

Title: [Effect of angiogenesis inhibitor Rg3 on the growth and metastasis of gastric cancer in SCID mice].

Journal: Zhonghua wai ke za zhi [Chinese journal of surgery] 20020801

Title: [Antiangiogenesis of ginsenoside Rg3 in severe combined immunodeficient mice with human ovarian carcinoma].

Journal: Zhonghua fu chan ke za zhi 20020401

Title: Ginseng and ginsenoside Rg3, a newly identified active ingredient of ginseng, modulate Ca2+ channel currents in rat sensory neurons.

Journal: European journal of pharmacology 20020202

Title: Metabolism of 20(S)- and 20(R)-ginsenoside Rg3 by human intestinal bacteria and its relation to in vitro biological activities.

Journal: Biological & pharmaceutical bulletin 20020101

Title: Characterization of ginseng saponin ginsenoside-Rg(3) inhibition of catecholamine secretion in bovine adrenal chromaffin cells.

Journal: Biochemical pharmacology 20011001

Title: [Pharmacokinetic studies of 20(R)-ginsenoside RG3 in human volunteers].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20010301

Title: Kim JH, et al. A role for the carbohydrate portion of ginsenoside Rg3 in Na+ channel inhibition. Mol Cells. 2005 Feb 28;19(1):137-42.

Title: Lee JH, et al. Ginsenoside Rg3 inhibits human Kv1.4 channel currents by interacting with the Lys531 residue. Mol Pharmacol. 2008 Mar;73(3):619-26.

Title: Lee IS, et al. Anti-Inflammatory Effects of Ginsenoside Rg3 via NF-κB Pathway in A549 Cells and Human Asthmatic Lung Tissue. J Immunol Res. 2016;2016:7521601.

Title: Kang MS, et al. Modulation of lipid kinase PI4KIIα activity and lipid raft association of presenilin 1 underlies γ-secretase inhibition by ginsenoside (20S)-Rg3. J Biol Chem. 2013 Jul 19;288(29):20868-82.

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Tags:14197-60-5 Molecular Formula|14197-60-5 MDL|14197-60-5 SMILES|14197-60-5 Ginsenoside rg3