[1]Chemicalandpharmaceuticalbulletin,1986,vol.34,p.1473-1478
[2]Phytochemistry,1990,vol.29,p.2507-2508
[3]Heterocycles,1984,vol.21,p.705
[4]Phytochemistry,1986,vol.25,p.2759-2764
Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Journal: Bioorganic & medicinal chemistry 20121115
Title: Orthosteric and allosteric drug binding sites in the Caenorhabditis elegans mgl-2 metabotropic glutamate receptor.
Journal: Neuropharmacology 20120901
Title: Ligand bias at metabotropic glutamate 1a receptors: molecular determinants that distinguish β-arrestin-mediated from G protein-mediated signaling.
Journal: Molecular pharmacology 20120801
Title: Weak BMAA toxicity compares with that of the dietary supplement β-alanine.
Journal: Neurobiology of aging 20120701
Title: The loss of an electrostatic contact unique to AMPA receptor ligand binding domain 2 slows channel activation.
Journal: Biochemistry 20120515
Title: Metabotropic glutamate receptor-1: a potential therapeutic target for the treatment of breast cancer.
Journal: Breast cancer research and treatment 20120401
Title: Selective and sustained α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor activation in cerebellum induces dystonia in mice.
Journal: The Journal of pharmacology and experimental therapeutics 20120301
Title: Anti-Alcohol and Anxiolytic Properties of a New Chemical Entity, GET73.
Journal: Frontiers in psychiatry 20120101
Title: Selective cholinergic depletion in medial septum leads to impaired long term potentiation and glutamatergic synaptic currents in the hippocampus.
Journal: PloS one 20120101
Title: Estradiol treatment prevents injury induced enhancement in spinal cord dynorphin expression.
Journal: Frontiers in physiology 20120101
Title: Dynamic regulation of NMDAR function in the adult brain by the stress hormone corticosterone.
Journal: Frontiers in cellular neuroscience 20120101
Title: Deleterious GRM1 mutations in schizophrenia.
Journal: PloS one 20120101
Title: Potential for Cell-Transplant Therapy with Human Neuronal Precursors to Treat Neuropathic Pain in Models of PNS and CNS Injury: Comparison of hNT2.17 and hNT2.19 Cell Lines.
Journal: Pain research and treatment 20120101
Title: Cortical development of AMPA receptor trafficking proteins.
Journal: Frontiers in molecular neuroscience 20120101
Title: Hippocampal dendritic spines modifications induced by perinatal asphyxia.
Journal: Neural plasticity 20120101
Title: Predifferentiated GABAergic neural precursor transplants for alleviation of dysesthetic central pain following excitotoxic spinal cord injury.
Journal: Frontiers in physiology 20120101
Title: Comparison of the spinal neuropathic pain induced by intraspinal injection of N-methyl-d-aspartate and quisquate in rats.
Journal: Journal of Korean Neurosurgical Society 20111101
Title: Sex differences in effects of excitotoxic spinal injury on below-level pain sensitivity.
Journal: Brain research 20111024
Title: Glutamatergic modulation of separation distress: profound emotional effects of excitatory amino acids in chicks.
Journal: Neuroscience and biobehavioral reviews 20111001
Title: Preclinical profile of a novel metabotropic glutamate receptor 5 positive allosteric modulator.
Journal: European journal of pharmacology 20110601
Title: Kynurenine metabolites and migraine: experimental studies and therapeutic perspectives.
Journal: Current neuropharmacology 20110601
Title: Quantitative analysis reveals multiple mechanisms of allosteric modulation of the mGlu5 receptor in rat astroglia.
Journal: Molecular pharmacology 20110501
Title: Reaction of endogenous progenitor cells in a rat model of posttraumatic syringomyelia.
Journal: Journal of neurosurgery. Spine 20110501
Title: Posttraumatic syringomyelia.
Journal: Journal of neurosurgery. Spine 20110501
Title: From toxins targeting ligand gated ion channels to therapeutic molecules.
Journal: Toxins 20110301
Title: Aqueous and Ethanolic Valeriana officinalis Extracts Change the Binding of Ligands to Glutamate Receptors.
Journal: Evidence-based complementary and alternative medicine : eCAM 20110101
Title: Physiological experimentation with the crayfish hindgut: a student laboratory exercise.
Journal: Journal of visualized experiments : JoVE 20110101
Title: Therapeutic hypothermia: critical review of the molecular mechanisms of action.
Journal: Frontiers in neurology 20110101
Title: mGluR5 positive modulators both potentiate activation and restore inhibition in NMDA receptors by PKC dependent pathway.
Journal: Journal of biomedical science 20110101
Title: Expression and localization of CLC chloride transport proteins in the avian retina.
Journal: PloS one 20110101
Title: The animal model of spinal cord injury as an experimental pain model.
Journal: Journal of biomedicine & biotechnology 20110101
Title: Rehabilitating a brain with Alzheimer's: a proposal.
Journal: Clinical interventions in aging 20110101
Title: Cholinergic interneurons mediate fast VGluT3-dependent glutamatergic transmission in the striatum.
Journal: PloS one 20110101
Title: Physiological properties of enkephalin-containing neurons in the spinal dorsal horn visualized by expression of green fluorescent protein in BAC transgenic mice.
Journal: BMC neuroscience 20110101
Title: Selective Interactions of Valeriana officinalis Extracts and Valerenic Acid with [H]Glutamate Binding to Rat Synaptic Membranes.
Journal: Evidence-based complementary and alternative medicine : eCAM 20110101
Title: Excitotoxicity triggered by Neurobasal culture medium.
Journal: PloS one 20110101
Title: Determinants of functional coupling between astrocytes and respiratory neurons in the pre-Bötzinger complex.
Journal: PloS one 20110101
Title: Distribution of extracellular glutamate in the neuropil of hippocampus.
Journal: PloS one 20110101
Title: Modulation of synaptic plasticity by stress hormone associates with plastic alteration of synaptic NMDA receptor in the adult hippocampus.
Journal: PloS one 20110101
Title: Simulation of postsynaptic glutamate receptors reveals critical features of glutamatergic transmission.
Journal: PloS one 20110101
Title: Extracellular glutamate: functional compartments operate in different concentration ranges.
Journal: Frontiers in systems neuroscience 20110101
Title: Evaluation of cannabinoid receptor 2 and metabotropic glutamate receptor 1 functional responses using a cell impedance-based technology.
Journal: Journal of biomolecular screening 20101201
Title: Expression of KA1 kainate receptor subunit in the substantia gelatinosa of the trigeminal subnucleus caudalis in mice.
Journal: Journal of veterinary science 20101201
Title: A post-burst after depolarization is mediated by group i metabotropic glutamate receptor-dependent upregulation of Ca(v)2.3 R-type calcium channels in CA1 pyramidal neurons.
Journal: PLoS biology 20101101
Title: Lateral diffusion of inositol 1,4,5-trisphosphate receptor type 1 in Purkinje cells is regulated by calcium and actin filaments.
Journal: Journal of neurochemistry 20100901
Title: Characterization of apical and basal thiol-disulfide redox regulation in human colonic epithelial cells.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20100801
Title: Central Pain from Excitotoxic Spinal Cord Injury Induced by Intraspinal NMDA Injection: A Pilot Study.
Journal: The Korean journal of pain 20100601
Title: Conformationally-restricted amino acid analogues bearing a distal sulfonic acid show selective inhibition of system x(c)(-) over the vesicular glutamate transporter.
Journal: Bioorganic & medicinal chemistry letters 20100415
Title: Involvement of ERK2 in traumatic spinal cord injury.
Journal: Journal of neurochemistry 20100401
Title: Potent homocysteine-induced ERK phosphorylation in cultured neurons depends on self-sensitization via system Xc(-).
Journal: Toxicology and applied pharmacology 20100115
Title: A glycine receptor is involved in the organization of swimming movements in an invertebrate chordate.
Journal: BMC neuroscience 20100101
Title: Selective serotonin reuptake inhibitors potentiate the rapid antidepressant-like effects of serotonin4 receptor agonists in the rat.
Journal: PloS one 20100101
Title: Pyk2 uncouples metabotropic glutamate receptor G protein signaling but facilitates ERK1/2 activation.
Journal: Molecular brain 20100101
Title: Alterations in ZENK and glucagon RNA transcript expression during increased ocular growth in chickens.
Journal: Molecular vision 20100101
Title: Marine drugs from sponge-microbe association--a review.
Journal: Marine drugs 20100101
Title: Confocal Analysis of Cholinergic and Dopaminergic Inputs onto Pyramidal Cells in the Prefrontal Cortex of Rodents.
Journal: Frontiers in neuroanatomy 20100101
Title: The human gonadotropin releasing hormone type I receptor is a functional intracellular GPCR expressed on the nuclear membrane.
Journal: PloS one 20100101
Title: Glutamatergic mechanisms for speed control and network operation in the rodent locomotor CpG.
Journal: Frontiers in neural circuits 20100101
Title: Modes of Neuronal Calcium Entry and Homeostasis following Cerebral Ischemia.
Journal: Stroke research and treatment 20100101
Title: Metabotropic glutamate receptors: potential drug targets for psychiatric disorders.
Journal: The open medicinal chemistry journal 20100101
Title: α7 Nicotinic Receptor Agonists: Potential Therapeutic Drugs for Treatment of Cognitive Impairments in Schizophrenia and Alzheimer's Disease.
Journal: The open medicinal chemistry journal 20100101
Title: Ammonia production, excretion, toxicity, and defense in fish: a review.
Journal: Frontiers in physiology 20100101
Title: Cortico-striatal spike-timing dependent plasticity after activation of subcortical pathways.
Journal: Frontiers in synaptic neuroscience 20100101
Title: Tryptophan, Neurodegeneration and HIV-Associated Neurocognitive Disorder.
Journal: International journal of tryptophan research : IJTR 20100101
Title: Functional expression of two system A glutamine transporter isoforms in rat auditory brainstem neurons.
Journal: Neuroscience 20091215
Title: Effects of positive allosteric modulators on single-cell oscillatory Ca2+ signaling initiated by the type 5 metabotropic glutamate receptor.
Journal: Molecular pharmacology 20091201
Title: Furthering pharmacological and physiological assessment of the glutamatergic receptors at the Drosophila neuromuscular junction.
Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20091101
Title: Agonist-induced internalization of mGluR1alpha is mediated by caveolin.
Journal: Journal of neurochemistry 20091001
Title: Effects of TRH and its analogues on primary cortical neuronal cell damage induced by various excitotoxic, necrotic and apoptotic agents.
Journal: Neuropeptides 20091001
Title: Structural insight into the evolutionary and pharmacologic homology of glutamate carboxypeptidases II and III.
Journal: The FEBS journal 20090801
Title: Activation of metabotropic glutamate receptors induces periodic burst firing and concomitant cytosolic Ca2+ oscillations in cerebellar interneurons.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090722
Title: Pre-differentiated embryonic stem cells promote neuronal regeneration by cross-coupling of BDNF and IL-6 signaling pathways in the host tissue.
Journal: Journal of neurotrauma 20090701
Title: Towards a reconceptualization of striatal interactions between glutamatergic and dopaminergic neurotransmission and their contribution to the production of movements.
Journal: Current neuropharmacology 20090601
Title: Characterization of ionotropic glutamate receptors in insect neuro-muscular junction.
Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20090401
Title: Identification of single nucleotide polymorphisms of the human metabotropic glutamate receptor 1 gene and pharmacological characterization of a P993S variant.
Journal: Biochemical pharmacology 20090401
Title: Glutamate-induced post-activation inhibition of locus coeruleus neurons is mediated by AMPA/kainate receptors and sodium-dependent potassium currents.
Journal: British journal of pharmacology 20090201
Title: Subtype selective kainic acid receptor agonists: discovery and approaches to rational design.
Journal: Medicinal research reviews 20090101
Title: Expression of muscarinic receptor subtypes in tree shrew ocular tissues and their regulation during the development of myopia.
Journal: Molecular vision 20090101
Title: Clinical feasibility for cell therapy using human neuronal cell line to treat neuropathic behavioral hypersensitivity following spinal cord injury in rats.
Journal: Journal of rehabilitation research and development 20090101
Title: Long-term potentiation in isolated dendritic spines.
Journal: PloS one 20090101
Title: Synaptic NR2A- but not NR2B-Containing NMDA Receptors Increase with Blockade of Ionotropic Glutamate Receptors.
Journal: Frontiers in molecular neuroscience 20090101
Title: Dermatomal scratching after intramedullary quisqualate injection: correlation with cutaneous denervation.
Journal: The journal of pain : official journal of the American Pain Society 20081101
Title: EphrinB2 induces tyrosine phosphorylation of NR2B via Src-family kinases during inflammatory hyperalgesia.
Journal: Neuroscience 20080922
Title: Group I metabotropic glutamate receptors control proliferation, survival and differentiation of cultured neural progenitor cells isolated from the subventricular zone of adult mice.
Journal: Neuropharmacology 20080901
Title: 2-(7,8-Diphenyl-1H-imidazo[4,5-f]quinoxalin-2-yl)phenol methanol disolvate.
Journal: Acta crystallographica. Section E, Structure reports online 20080901
Title: Chemo-enzymatic synthesis of a series of 2,4-syn-functionalized (S)-glutamate analogues: new insight into the structure-activity relation of ionotropic glutamate receptor subtypes 5, 6, and 7.
Journal: Journal of medicinal chemistry 20080724
Title: Neuromodulatory role of acetylcholine in visually-induced cortical activation: behavioral and neuroanatomical correlates.
Journal: Neuroscience 20080717
Title: Pharmacology of ionotropic and metabotropic glutamate receptors on neurons involved in feeding behavior in the pond snail, Helisoma trivolvis.
Journal: The Journal of experimental biology 20080301
Title: Domoic acid toxicologic pathology: a review.
Journal: Marine drugs 20080301
Title: Inducible expression and pharmacological characterization of the mouse metabotropic glutamate 5b receptor.
Journal: European journal of pharmacology 20080128
Title: Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080123
Title: Regulatory roles of Ca2+/calmodulin-dependent protein kinase II and protein phosphatase 2A on the quisqualic acid-induced K+-current response in identified neurons of Aplysia.
Journal: Neuroscience research 20080101
Title: Muscarinic signaling influences the patterning and phenotype of cholinergic amacrine cells in the developing chick retina.
Journal: BMC developmental biology 20080101
Title: Neuroprotective and anticonvulsant effects of EGIS-8332, a non-competitive AMPA receptor antagonist, in a range of animal models.
Journal: British journal of pharmacology 20070901
Title: Structural insight into the pharmacophore pocket of human glutamate carboxypeptidase II.
Journal: Journal of medicinal chemistry 20070712
Title: Mitochondrial aspartate aminotransferase: a third kynurenate-producing enzyme in the mammalian brain.
Journal: Journal of neurochemistry 20070701
Title: Metabotropic glutamate receptor/phospholipase C system in female rat heart.
Journal: Brain research 20070611
Title: Pharmacological characterization of a new, orally active and potent allosteric metabotropic glutamate receptor 1 antagonist, 4-[1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide (FTIDC).
Journal: The Journal of pharmacology and experimental therapeutics 20070601
Title: Mechanisms of modafinil: A review of current research.
Journal: Neuropsychiatric disease and treatment 20070601
Title: Nuclear localization of functional metabotropic glutamate receptor mGlu1 in HEK293 cells and cortical neurons: role in nuclear calcium mobilization and development.
Journal: Journal of neurochemistry 20070401
Title: Human glutamate carboxypeptidase II inhibition: structures of GCPII in complex with two potent inhibitors, quisqualate and 2-PMPA.
Journal: Acta crystallographica. Section D, Biological crystallography 20070401
Title: Lesions to the nucleus basalis magnocellularis lower performance but do not block the retention of a previously acquired learning set.
Journal: Brain research 20070309
Title: Optimizing the transplant dose of a human neuronal cell line graft to treat SCI pain in the rat.
Journal: Neuroscience letters 20070306
Title: The lathyrus toxin, beta-N-oxalyl-L-alpha,beta-diaminopropionic acid (ODAP), and homocysteic acid sensitize CA1 pyramidal neurons to cystine and L-2-amino-6-phosphonohexanoic acid.
Journal: Toxicology and applied pharmacology 20070215
Title: The new 2,3-benzodiazepine derivative EGIS-8332 inhibits AMPA/kainate ion channels and cell death.
Journal: Neurochemistry international 20070201
Title: ABP688, a novel selective and high affinity ligand for the labeling of mGlu5 receptors: identification, in vitro pharmacology, pharmacokinetic and biodistribution studies.
Journal: Bioorganic & medicinal chemistry 20070115
Title: Subarachnoid transplant of a human neuronal cell line attenuates chronic allodynia and hyperalgesia after excitotoxic spinal cord injury in the rat.
Journal: The journal of pain : official journal of the American Pain Society 20070101
Title: Pigment epithelium-derived factor protects retinal ganglion cells.
Journal: BMC neuroscience 20070101
Title: Spinal and supraspinal changes in tumor necrosis factor-alpha expression following excitotoxic spinal cord injury.
Journal: Journal of molecular neuroscience : MN 20070101
Title: Stress before puberty exerts a sex- and age-related impact on auditory and contextual fear conditioning in the rat.
Journal: Neural plasticity 20070101
Title: Ronald Tasker Award: Intrathecal transplantation of a human neuronal cell line for the treatment of neuropathic pain in a spinal cord injury model.
Journal: Clinical neurosurgery 20070101
Title: Mechanisms underlying type I mGluR-induced activation of lobster gastric mill neurons.
Journal: Journal of neurophysiology 20061201
Title: Intracellular calcium is regulated by different pathways in horizontal cells of the mouse retina.
Journal: Journal of neurophysiology 20060901
Title: The relationship between agonist potency and AMPA receptor kinetics.
Journal: Biophysical journal 20060815
Title: Stimulation of oncogenic metabotropic glutamate receptor 1 in melanoma cells activates ERK1/2 via PKCepsilon.
Journal: Cellular signalling 20060801
Title: Group I mGlu receptor stimulation inhibits activation-induced cell death of human T lymphocytes.
Journal: British journal of pharmacology 20060701
Title: Comparison of the binding pockets of two chemically unrelated allosteric antagonists of the mGlu5 receptor and identification of crucial residues involved in the inverse agonism of MPEP.
Journal: Journal of neurochemistry 20060701
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Expression of the cystine-glutamate exchanger (xc-) in retinal ganglion cells and regulation by nitric oxide and oxidative stress.
Journal: Cell and tissue research 20060501
Title: Actions of glutamate and ivermectin on the pharyngeal muscle of Ascaridia galli: a comparative study with Caenorhabditis elegans.
Journal: International journal for parasitology 20060401
Title: Sodium- and magnesium-valproate in vivo modulate glutamatergic and GABAergic synapses in the medial prefrontal cortex.
Journal: Psychopharmacology 20060401
Title: Effects of muscarinic antagonists on ZENK expression in the chicken retina.
Journal: Experimental eye research 20060301
Title: Non-NMDA glutamatergic receptors modulate acetylcholine release in the rat subfornical organ area.
Journal: Autonomic neuroscience : basic & clinical 20060130
Title: Nitric oxide in the amphibian (Ambystoma tigrinum) lateral line.
Journal: Neuroscience letters 20060123
Title: Novel bioactive bromopyrrole alkaloids from the Mediterranean sponge Axinella verrucosa.
Journal: Bioorganic & medicinal chemistry 20060101
Title: The glutamate story.
Journal: British journal of pharmacology 20060101
Title: Selective up-regulation of NMDA-NR1 receptor expression in myenteric plexus after TNBS induced colitis in rats.
Journal: Molecular pain 20060101
Title: Predifferentiated embryonic stem cells prevent chronic pain behaviors and restore sensory function following spinal cord injury in mice.
Journal: Molecular medicine (Cambridge, Mass.) 20060101
Title: Glutamate receptors in neuroinflammatory demyelinating disease.
Journal: Mediators of inflammation 20060101
Title: Differences in forebrain activation in two strains of rat at rest and after spinal cord injury.
Journal: Experimental neurology 20051201
Title: Functional metabotropic glutamate receptors on nuclei from brain and primary cultured striatal neurons. Role of transporters in delivering ligand.
Journal: The Journal of biological chemistry 20050826
Title: Activation of the ERK1/2 signaling cascade by excitotoxic spinal cord injury.
Journal: Brain research. Molecular brain research 20050818
Title: Evaluation of the pathologic characteristics of excitotoxic spinal cord injury with MR imaging.
Journal: AJNR. American journal of neuroradiology 20050801
Title: Phosphorylation-independent regulation of metabotropic glutamate receptor 1 signaling requires g protein-coupled receptor kinase 2 binding to the second intracellular loop.
Journal: The Journal of biological chemistry 20050701
Title: Effects of estrone on quisqualate-induced toxicity in primary cultures of rat cortical neurons.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20050601
Title: The neural substrates of infant sleep in rats.
Journal: PLoS biology 20050501
Title: AMPA receptor binding cleft mutations that alter affinity, efficacy, and recovery from desensitization.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050413
Title: A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models.
Journal: The Journal of pharmacology and experimental therapeutics 20050401
Title: Constitutive activity modulation of human metabotropic glutamate 5a receptors in HEK293 cells: a role for key amino-terminal cysteine residues.
Journal: British journal of pharmacology 20050401
Title: Group I metabotropic glutamate receptors, mGlu1a and mGlu5a, couple to cyclic AMP response element binding protein (CREB) through a common Ca2+ - and protein kinase C-dependent pathway.
Journal: Journal of neurochemistry 20050401
Title: Antinociceptive interactions between intrathecal gabapentin and MK801 or NBQX in rat formalin test.
Journal: Journal of Korean medical science 20050401
Title: Microsecond-to-millisecond conformational dynamics demarcate the GluR2 glutamate receptor bound to agonists glutamate, quisqualate, and AMPA.
Journal: Biochemistry 20050308
Title: Interactions between ephrin-B and metabotropic glutamate 1 receptors in brain tissue and cultured neurons.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050302
Title: Antagonist-induced supersensitivity of mGlu1 receptor signalling in cerebellar granule cells.
Journal: The European journal of neuroscience 20050301
Title: Crystal structures of the GluR5 and GluR6 ligand binding cores: molecular mechanisms underlying kainate receptor selectivity.
Journal: Neuron 20050217
Title: Distinct modulatory roles of sigma receptor subtypes on glutamatergic responses in the dorsal hippocampus.
Journal: Synapse (New York, N.Y.) 20050101
Title: Active medullary control of atonia in week-old rats.
Journal: Neuroscience 20050101
Title: Central neuropathic itch from spinal-cord cavernous hemangioma: a human case, a possible animal model, and hypotheses about pathogenesis.
Journal: Pain 20050101
Title: Endogenous activation of mGlu5 metabotropic glutamate receptors supports self-renewal of cultured mouse embryonic stem cells.
Journal: Neuropharmacology 20050101
Title: The Lathyrus excitotoxin beta-N-oxalyl-L-alpha,beta-diaminopropionic acid is a substrate of the L-cystine/L-glutamate exchanger system xc-.
Journal: Toxicology and applied pharmacology 20041015
Title: Abnormal metabotropic glutamate receptor expression and signaling in the cerebral cortex in diffuse Lewy body disease is associated with irregular alpha-synuclein/phospholipase C (PLCbeta1) interactions.
Journal: Brain pathology (Zurich, Switzerland) 20041001
Title: Excitatory amino acid induced oligodendrocyte cell death in vitro: receptor-dependent and -independent mechanisms.
Journal: Journal of neurochemistry 20040901
Title: Mutation-induced quisqualic acid and ibotenic acid affinity at the metabotropic glutamate receptor subtype 4: ligand selectivity results from a synergy of several amino acid residues.
Journal: The Journal of biological chemistry 20040813
Title: Characterization of a domoic acid binding site from Pacific razor clam.
Journal: Aquatic toxicology (Amsterdam, Netherlands) 20040810
Title: Interaction between intrathecal gabapentin and adenosine in the formalin test of rats.
Journal: Journal of Korean medical science 20040801
Title: Nefopam blocks voltage-sensitive sodium channels and modulates glutamatergic transmission in rodents.
Journal: Brain research 20040709
Title: Spinal neurons involved in the generation of at-level pain following spinal injury in the rat.
Journal: Neuroscience letters 20040506
Title: A novel selective allosteric modulator potentiates the activity of native metabotropic glutamate receptor subtype 5 in rat forebrain.
Journal: The Journal of pharmacology and experimental therapeutics 20040501
Title: Analogues of homoibotenic acid show potent and selective activity following sensitisation by quisqualic acid.
Journal: European journal of pharmacology 20040319
Title: Differentiation of substrate and non-substrate inhibitors of transport system xc(-): an obligate exchanger of L-glutamate and L-cystine.
Journal: Neuropharmacology 20040201
Title: Neuroprotective effects of nicotinamide after experimental spinal cord injury.
Journal: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20040201
Title: Effects of quisqualic acid on retinal ZENK expression induced by imposed defocus in the chick eye.
Journal: Optometry and vision science : official publication of the American Academy of Optometry 20040201
Title: The effects of endogenous interleukin-10 on gray matter damage and the development of pain behaviors following excitotoxic spinal cord injury in the mouse.
Journal: Neuroscience 20040101
Title: Glutamate-mediated cytosolic calcium oscillations regulate a pulsatile prostaglandin release from cultured rat astrocytes.
Journal: The Journal of physiology 20031201
Title: Blockade of excitatory amino acid transporters in the rat hippocampus results in enhanced activation of group I and group III metabotropic glutamate receptors.
Journal: Neuropharmacology 20031201
Title: PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis.
Journal: Nature neuroscience 20031101
Title: Mutational analysis and molecular modeling of the binding pocket of the metabotropic glutamate 5 receptor negative modulator 2-methyl-6-(phenylethynyl)-pyridine.
Journal: Molecular pharmacology 20031001
Title: N-methyl-D-aspartate receptor subunit expression and phosphorylation following excitotoxic spinal cord injury in rats.
Journal: Neuroscience letters 20030925
Title: A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5.
Journal: Molecular pharmacology 20030901
Title: The role of excitotoxic injury in post-traumatic syringomyelia.
Journal: Journal of neurotrauma 20030901
Title: Nerve growth factor response to excitotoxic lesion of the cholinergic basal forebrain is slightly impaired in aged rats.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20030601
Title: Fluid flow in an animal model of post-traumatic syringomyelia.
Journal: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 20030601
Title: [3H]R214127: a novel high-affinity radioligand for the mGlu1 receptor reveals a common binding site shared by multiple allosteric antagonists.
Journal: Molecular pharmacology 20030501
Title: Pharmacological properties of l-glutamate receptors associated with the crayfish hindgut.
Journal: Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20030501
Title: Role of G protein-coupled receptor kinase 4 and beta-arrestin 1 in agonist-stimulated metabotropic glutamate receptor 1 internalization and activation of mitogen-activated protein kinases.
Journal: The Journal of biological chemistry 20030404
Title: Age-related differences in NMDA/metabotropic glutamate receptor binding in rat substantia nigra.
Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20030401
Title: A new acylglycosyl sterol from Quisqualis Fructus.
Journal: Archives of pharmacal research 20030401
Title: Effects of agmatine, interleukin-10, and cyclosporin on spontaneous pain behavior after excitotoxic spinal cord injury in rats.
Journal: The journal of pain : official journal of the American Pain Society 20030401
Title: Mutational analysis and molecular modeling of the allosteric binding site of a novel, selective, noncompetitive antagonist of the metabotropic glutamate 1 receptor.
Journal: The Journal of biological chemistry 20030307
Title: Metabotropic glutamate receptor activation enhances the activities of two types of Ca2+-activated k+ channels in rat hippocampal astrocytes.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030301
Title: Enhancing action of LSD on neuronal responsiveness to serotonin in a brain structure involved in obsessive-compulsive disorder.
Journal: The international journal of neuropsychopharmacology 20030301
Title: Amino acid mutagenesis of the ligand binding site and the dimer interface of the metabotropic glutamate receptor 1. Identification of crucial residues for setting the activated state.
Journal: The Journal of biological chemistry 20030207
Title: Neurohormonal and glutamatergic neuronal control of the cardioarterial valves in the isopod crustacean Bathynomus doederleini.
Journal: The Journal of experimental biology 20030201
Title: Ionotropic glutamate receptors in cerebral microvascular endothelium are functionally linked to heme oxygenase.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20030201
Title: The selective cyclooxygenase-2 inhibitor rofecoxib suppresses brain inflammation and protects cholinergic neurons from excitotoxic degeneration in vivo.
Journal: Neuroscience 20030101
Title: Structure of glutamate analogs that activate the ON bipolar cell metabotropic glutamate receptor in vertebrate retina.
Journal: Visual neuroscience 20030101
Title: Mechanism of activation and selectivity in a ligand-gated ion channel: structural and functional studies of GluR2 and quisqualate.
Journal: Biochemistry 20021231
Title: Characterization of mGluR5R, a novel, metabotropic glutamate receptor 5-related gene.
Journal: Brain research. Molecular brain research 20021230
Title: Identification and characterization of a novel splice variant of the metabotropic glutamate receptor 5 gene in human hippocampus and cerebellum.
Journal: Brain research. Molecular brain research 20021230
Title: Group-I metabotropic glutamate receptors, mGlu1a and mGlu5a, couple to extracellular signal-regulated kinase (ERK) activation via distinct, but overlapping, signalling pathways.
Journal: Journal of neurochemistry 20021201
Title: A pharmacological analysis of the contractile effects of glutamate on rat and human isolated gut smooth muscle strips.
Journal: Methods and findings in experimental and clinical pharmacology 20021201
Title: Lead can inhibit NMDA-, K(+)-, QA/KA-induced increases in intracellular free Ca2+ in cultured rat hippocampal neurons.
Journal: Biomedical and environmental sciences : BES 20021201
Title: Culturing and characterization of astrocytes isolated from juvenile rainbow trout (Oncorhynchus mykiss).
Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20020901
Title: VEGA: a versatile program to convert, handle and visualize molecular structure on Windows-based PCs.
Journal: Journal of molecular graphics & modelling 20020801
Title: Common and selective molecular determinants involved in metabotopic glutamate receptor agonist activity.
Journal: Journal of medicinal chemistry 20020718
Title: Ionotropic glutamate receptors mediate juvenile hormone synthesis in the cockroach, Diploptera punctata.
Journal: Insect biochemistry and molecular biology 20020601
Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
Journal: The Journal of biological chemistry 20020419
Title: The non-competitive AMPA receptor antagonist (GYKI 52466) blocks quisqualate-induced acetylcholine release from the rat hippocampus and striatum: an in vivo microdialysis study.
Journal: Neurochemistry international 20020401
Title: Internalization of metabotropic glutamate receptor in C6 cells through clathrin-coated vesicles.
Journal: Brain research. Molecular brain research 20020227
Title: Expression of the nerve growth factor receptors TrkA and p75NTR in the visual cortex of the rat: development and regulation by the cholinergic input.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020201
Title: Glutamate receptors on the somata of dorsal unpaired median neurons in cockroach, Periplaneta americana, thoracic ganglia.
Journal: Zoological science 20020201
Title: Characterization of an N-terminal secreted domain of the type-1 human metabotropic glutamate receptor produced by a mammalian cell line.
Journal: Journal of neurochemistry 20020101
Title: A novel binding assay for metabotropic glutamate receptors using [3H] L-quisqualic acid and recombinant receptors.
Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20020101
Title: Use of excitotoxins to lesion the hippocampus: update.
Journal: Hippocampus 20020101
Title: Nitric oxide synthase inhibition and glutamate binding in quinolinate-lesioned rat hippocampus.
Journal: Physiological research 20020101
Title: Influence of serotonin on the glutamate-induced excitations of secondary vestibular neurons in the rat.
Journal: Experimental neurology 20011201
Title: Positive allosteric modulators of metabotropic glutamate 1 receptor: characterization, mechanism of action, and binding site.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20011106
Title: Glutamate receptor desensitization block potentiates the stimulated GABA release through external Ca2+-independent mechanisms from granule cells of olfactory bulb.
Journal: Neurochemical research 20011101
Title: Protective effect of excitatory amino acids on cold-restraint stress-induced gastric ulcers in mice: role of cyclic nucleotides.
Journal: Digestive diseases and sciences 20011001
Title: Binding of the glutamate carboxypeptidase II (NAALADase) inhibitor 2-PMPA to rat brain membranes.
Journal: European journal of pharmacology 20010914
Title: Excitotoxic model of post-traumatic syringomyelia in the rat.
Journal: Spine 20010901
Title: Physiological and pharmacological characteristics of quisqualic acid-induced K(+)-current response in the ganglion cells of Aplysia.
Journal: The Japanese journal of physiology 20010801
Title: Differential effects of glutamate agonists and D-aspartate on oxytocin release from hypothalamus and posterior pituitary of male rats.
Journal: Endocrine 20010801
Title: Conditions affecting the onset, severity, and progression of a spontaneous pain-like behavior after excitotoxic spinal cord injury.
Journal: The journal of pain : official journal of the American Pain Society 20010801
Title: Expression of c-fos mRNA is increased and related to dynorphin mRNA expression following excitotoxic spinal cord injury in the rat.
Journal: Neuroscience letters 20010720
Title: Dibutyryl-cAMP (dbcAMP) up-regulates astrocytic chloride-dependent L-[3H]glutamate transport and expression of both system xc(-) subunits.
Journal: Journal of neurochemistry 20010701
Title: Reassessment of the Ca2+ sensing property of a type I metabotropic glutamate receptor by simultaneous measurement of inositol 1,4,5-trisphosphate and Ca2+ in single cells.
Journal: The Journal of biological chemistry 20010601
Title: Enhanced inducible mGlu1alpha receptor expression in Chinese hamster ovary cells.
Journal: Journal of neurochemistry 20010601
Title: NO-flurbiprofen attenuates excitotoxin-induced brain inflammation, and releases nitric oxide in the brain.
Journal: Japanese journal of pharmacology 20010601
Title: Characterization of glutamate-gated chloride channels in the pharynx of wild-type and mutant Caenorhabditis elegans delineates the role of the subunit GluCl-alpha2 in the function of the native receptor.
Journal: Molecular pharmacology 20010501
Title: Inhibition of choline acetyltransferase by excitatory amino acids as a possible mechanism for cholinergic dysfunction in the central nervous system.
Journal: Journal of neurochemistry 20010501
Title: A Na+-dependent electrogenic glutamate transporter current in voltage-clamped cells of corpora allata in the cricket Gryllus bimaculatus.
Journal: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20010501
Title: Cloning and characterization of a human orphan family C G-protein coupled receptor GPRC5D.
Journal: Biochimica et biophysica acta 20010416
Title: Cell type-specific differences in the coupling of recombinant mGlu1alpha receptors to endogenous G protein sub-populations.
Journal: Neuropharmacology 20010401
Title: An activity-dependent switch from facilitation to inhibition in the control of excitotoxicity by group I metabotropic glutamate receptors.
Journal: The European journal of neuroscience 20010401
Title: The effects of nucleus basalis magnocellularis lesions in Long-Evans hooded rats on two learning set formation tasks, delayed matching-to-sample learning, and open-field activity.
Journal: Behavioral neuroscience 20010401
Title: [Synthesis and release of N-acetylaspartyl glutamate (NAAG) in medial giant axons in crayfish].
Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20010401
Title: Tetanic stimulation and metabotropic glutamate receptor agonists modify synaptic responses and protein kinase activity in rat auditory cortex.
Journal: Brain research 20010316
Title: Methylmercury inhibits the in vitro uptake of the glutathione precursor, cystine, in astrocytes, but not in neurons.
Journal: Brain research 20010309
Title: Characterization with [3H]quisqualate of group I metabotropic glutamate receptor subtype in rat central and peripheral excitable tissues.
Journal: Neurochemistry international 20010301
Title: Effects of interleukin-10 (IL-10) on pain behavior and gene expression following excitotoxic spinal cord injury in the rat.
Journal: Experimental neurology 20010301
Title: Cajal-Retzius cells in early postnatal mouse cortex selectively express functional metabotropic glutamate receptors.
Journal: The European journal of neuroscience 20010301
Title: Metabotropic glutamate receptor type 1alpha and tubulin assemble into dynamic interacting complexes.
Journal: Journal of neurochemistry 20010201
Title: Spinal and supraspinal changes in opioid mRNA expression are related to the onset of pain behaviors following excitotoxic spinal cord injury.
Journal: Pain 20010201
Title: Covalent and noncovalent interactions mediate metabotropic glutamate receptor mGlu5 dimerization.
Journal: Molecular pharmacology 20010101
Title: Expression of ionotropic glutamate receptors in the retina of the rdta transgenic mouse.
Journal: BMC neuroscience 20010101
Title: The role of kainic acid/AMPA and metabotropic glutamate receptors in the regulation of opioid mRNA expression and the onset of pain-related behavior following excitotoxic spinal cord injury.
Journal: Neuroscience 20010101
Title: Synthesis and release of N-acetylaspartylglutamate (NAAG) by crayfish nerve fibers: implications for axon-glia signaling.
Journal: Neuroscience 20010101
Title: L-Quisqualic acid transport into hippocampal neurons by a cystine-sensitive carrier is required for the induction of quisqualate sensitization.
Journal: Neuroscience 20010101
Title: Mechanisms for clearance of released N-acetylaspartylglutamate in crayfish nerve fibers: implications for axon-glia signaling.
Journal: Neuroscience 20010101
Title: Cognitive effects of neurotoxic lesions of the nucleus basalis magnocellularis in rats: differential roles for corticopetal versus amygdalopetal projections.
Journal: Neurotoxicity research 20010101
Title: Characterization of [(3)H]Quisqualate binding to recombinant rat metabotropic glutamate 1a and 5a receptors and to rat and human brain sections.
Journal: Journal of neurochemistry 20001201
Title: Pharmacological characterization of the rat metabotropic glutamate receptor type 8a revealed strong similarities and slight differences with the type 4a receptor.
Journal: European journal of pharmacology 20000407
Title: Effect of the umami peptides on the ligand binding and function of rat mGlu4a receptor might implicate this receptor in the monosodium glutamate taste transduction.
Journal: British journal of pharmacology 19991101
Title: 2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist.
Journal: Neuropharmacology 19991001
Title: Propofol modulates the effects of chemoconvulsants acting at GABAergic, glycinergic, and glutamate receptor subtypes.
Journal: Anesthesiology 19951001
Title: Pharmacological analysis of 4-carboxyphenylglycine derivatives: comparison of effects on mGluR1 alpha and mGluR5a subtypes.
Journal: Neuropharmacology 19950801
Title: Felbamate displays in vitro antiepileptic effects as a broad spectrum excitatory amino acid receptor antagonist.
Journal: European journal of pharmacology 19941227
Title: Benzothiadiazides inhibit rapid glutamate receptor desensitization and enhance glutamatergic synaptic currents.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 19930901
Title: A pharmacological characterization of the mGluR1 alpha subtype of the metabotropic glutamate receptor expressed in a cloned baby hamster kidney cell line.
Journal: Brain research 19930813
Title: Anticonvulsant action of the beta-carboline abecarnil: studies in rodents and baboon, Papio papio.
Journal: The Journal of pharmacology and experimental therapeutics 19900401
Title: The involvement of excitatory amino acid receptors within the prepiriform cortex in pilocarpine-induced limbic seizures in rats.
Journal: Experimental brain research 19880101
Title: Amino acid neurotoxicity: relationship to neuronal depolarization in rat cerebellar slices.
Journal: Neuroscience 19860601
Title: Quantitative studies on some antagonists of N-methyl D-aspartate in slices of rat cerebral cortex.
Journal: British journal of pharmacology 19850201
Title: Hugues-Olivier Bertrand, et al. Common and Selective Molecular Determinants Involved in Metabotopic Glutamate Receptor Agonist Activity. J Med Chem. 2002 Jul 18;45(15):3171-83.
Title: H Bräuner-Osborne, et al. Ligands for Glutamate Receptors: Design and Therapeutic Prospects. J Med Chem. 2000 Jul 13;43(14):2609-45.
