53-60-1,MFCD00058535
Catalog No.:AA01A4TP

53-60-1 | Promazine hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
98%
in stock  
$66.00   $46.00
- +
250mg
95%
in stock  
$107.00   $75.00
- +
1g
98%
in stock  
$238.00   $167.00
- +
5g
98%
in stock  
$536.00   $375.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA01A4TP
Chemical Name:
Promazine hydrochloride
CAS Number:
53-60-1
Molecular Formula:
C17H21ClN2S
Molecular Weight:
320.8800
MDL Number:
MFCD00058535
SMILES:
CN(CCCN1c2ccccc2Sc2c1cccc2)C.Cl
Properties
Computed Properties
 
Complexity:
285  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  

Literature

Title: Interactions of phenothiazine drugs with bile salts: micellization and binding studies.

Journal: Journal of colloid and interface science 20121201

Title: Interaction of amphiphilic drugs with human and bovine serum albumins.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121101

Title: Acepromazine pharmacokinetics: a forensic perspective.

Journal: Veterinary journal (London, England : 1997) 20121001

Title: Promazine and chlorpromazine for prolonged spinal anesthesia in rats.

Journal: Neuroscience letters 20120719

Title: Phase behavior study of amphiphilic drugs: effect of pharmaceutical excipients.

Journal: Colloids and surfaces. B, Biointerfaces 20120615

Title: Use of potentiometric sensors to study (bio)molecular interactions.

Journal: Analytical chemistry 20120605

Title: Exanthema medicamentosum as a side effect of promazine.

Journal: Psychiatria Danubina 20110601

Title: Promazine in the treatment of delusional parasitosis.

Journal: Psychiatria Danubina 20110601

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Broad spectrum drug screening using electron-ionization gas chromatography-mass spectrometry (EI-GCMS).

Journal: Methods in molecular biology (Clifton, N.J.) 20100101

Title: Broad spectrum drug screening using liquid chromatography-hybrid triple quadrupole linear ion trap mass spectrometry.

Journal: Methods in molecular biology (Clifton, N.J.) 20100101

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: Simultaneous chemiluminescence determination of promazine and fluphenazine using support vector regression.

Journal: Talanta 20090715

Title: Use and misuse of antipsychotic drugs in patients with dementia in Alzheimer special care units.

Journal: International clinical psychopharmacology 20090301

Title: Chemiluminescence determination of promazine in human serum and drug formulations using Ru(phen)3(2+)-Ce(IV) system and a chemometrical optimization approach.

Journal: Luminescence : the journal of biological and chemical luminescence 20090101

Title: Acute intoxication by triazolam and promazine: a case report.

Journal: Medicine, science, and the law 20090101

Title: Validation of derivative spectrophotometry method for determination of active ingredients from neuroleptics in pharmaceutical preparations.

Journal: Acta poloniae pharmaceutica 20090101

Title: [Drug-induced agranulocytosis--case reports and literature review].

Journal: Przeglad lekarski 20090101

Title: Comparative study of the efficiency of synthetic and natural mediators in laccase-assisted bleaching of eucalyptus kraft pulp.

Journal: Bioresource technology 20081101

Title: The cardiorespiratory effects of a fentanyl infusion following acepromazine and glycopyrrolate in dogs.

Journal: Tijdschrift voor diergeneeskunde 20081101

Title: The psychotropic drug olanzapine (Zyprexa) increases the area of acid glycerophospholipid monolayers.

Journal: Biophysical chemistry 20080401

Title: Modification of the thermal unfolding pathways of myoglobin upon drug interaction in different aqueous media.

Journal: The journal of physical chemistry. B 20071213

Title: Thermodynamic studies of drug-alpha-cyclodextrin interactions in water at 298.15 K: promazine hydrochloride/chlorpromazine hydrochloride + alpha-cyclodextrin + H(2)O systems.

Journal: The journal of physical chemistry. B 20071206

Title: Synthesis and antitubercular activity of quaternized promazine and promethazine derivatives.

Journal: Bioorganic & medicinal chemistry letters 20070301

Title: Drug adverse events and drop-out risk: a clinical case.

Journal: Archives of gerontology and geriatrics 20070101

Title: Interactions of recombinant prions with compounds of therapeutical significance.

Journal: Biochemical and biophysical research communications 20060602

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Relation of postmortem blood alcohol and drug concentrations in fatal poisonings involving amitriptyline, propoxyphene and promazine.

Journal: Human & experimental toxicology 20050801

Title: Stability of the tranquilizer drug propionylpromazine hydrochloride in formulated products.

Journal: Pest management science 20050601

Title: Acute brain syndrome as a consequence of the Cronkhite-Canada syndrome.

Journal: Psychiatria Danubina 20050601

Title: Densitometric high performance thin-layer chromatography identification and quantitative analysis of psychotropic drugs.

Journal: Journal of AOAC International 20050101

Title: CSM thioridazine advice.

Journal: The British journal of general practice : the journal of the Royal College of General Practitioners 20040801

Title: CSM thioridazine advice.

Journal: The British journal of general practice : the journal of the Royal College of General Practitioners 20040801

Title: Old drugs as lead compounds for a new disease? Binding analysis of SARS coronavirus main proteinase with HIV, psychotic and parasite drugs.

Journal: Bioorganic & medicinal chemistry 20040515

Title: Comparison of the efficacy of new and conventional antipsychotic drugs in the treatment of behavioral and psychological symptoms of dementia (BPSD).

Journal: Archives of gerontology and geriatrics. Supplement 20040101

Title: Contribution of human cytochrome p-450 isoforms to the metabolism of the simplest phenothiazine neuroleptic promazine.

Journal: British journal of pharmacology 20030401

Title: Minimal myocardial damage after tricyclic neuroleptic overdose - a case report.

Journal: Pharmacopsychiatry 20030101

Title: Influence of classic and atypical neuroleptics on caffeine oxidation in rat liver microsomes.

Journal: Polish journal of pharmacology 20030101

Title: Analytical studies and application of reaction of promazine and thioridazine hydrochlorides with some oxidants.

Journal: Acta poloniae pharmaceutica 20030101

Title: The contribution of cytochrome P-450 isoenzymes to the metabolism of phenothiazine neuroleptics.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20021001

Title: Fructose-1,6-diphosphate attenuates acute lung injury induced by ischemia-reperfusion in rats.

Journal: Critical care medicine 20020701

Title: Intracellular distribution of psychotropic drugs in the grey and white matter of the brain: the role of lysosomal trapping.

Journal: British journal of pharmacology 20011001

Title: Use of laccase together with redox mediators to decolourize Remazol Brilliant Blue R.

Journal: Journal of biotechnology 20010823

Title: Application of reinecke salt and alizarin S for the determination of promazine.

Journal: Journal of pharmaceutical and biomedical analysis 20010801

Title: [Acute normovolemic hemodilution (ANH). Der Anaesthesist (2000) 49: 939-948].

Journal: Der Anaesthesist 20010801

Title: [The opinion of O. Habler].

Journal: Der Anaesthesist 20010801

Title: Spectrophotometric determination of vanadium(V) in minerals, steels, soil and biological samples using phenothiazine derivatives.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20010801

Title: A liquid chromatographic method for the simultaneous determination of promethazine and three of its metabolites in plasma using electrochemical and UV detectors.

Journal: Journal of chromatographic science 20010201

Title: Simultaneous quantification of promazine hydrochloride and its sulfoxide in pharmaceutical preparations.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20010201

Title: Examination of iron (III) and hexacyanoferrate (III) ions as reagents for the spectrophotometric determination of promazine and perazine.

Journal: Acta poloniae pharmaceutica 20010101

Title: Effects of xylazine and acetylpromazine upon induced ventricular fibrillation in dogs anesthetized with thiamylal and halothane.

Journal: American journal of veterinary research 19750901

Title: Tardive dyskinesia treated with pimozide.

Journal: Journal of the neurological sciences 19750401

Title: Neuroleptics and neurologic reactions.

Journal: Southern medical journal 19730301

Title: Mutism induced by phenothiazines.

Journal: The British journal of psychiatry : the journal of mental science 19721201

Title: Mental disorders caused by isonicotinic acid hydrazide (INH) in the course of treatment of pulmonary tuberculosis.

Journal: Polish medical journal 19700101

Title: Phenothiazines in early labour.

Journal: British medical journal 19670211

Title: Prolonged apnea after administration of promazine hydrochloride following succinylcholine infusion: a case report.

Journal: Anesthesia and analgesia 19670101

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Additional Info:
SDS
Historical Records
Tags:53-60-1 Molecular Formula|53-60-1 MDL|53-60-1 SMILES|53-60-1 Promazine hydrochloride
Catalog No.: AA01A4TP
53-60-1,MFCD00058535
53-60-1 | Promazine hydrochloride
Pack Size: 100mg
Purity: 98%
in stock
$66.00 $46.00
Pack Size: 250mg
Purity: 95%
in stock
$107.00 $75.00
Pack Size: 1g
Purity: 98%
in stock
$238.00 $167.00
Pack Size: 5g
Purity: 98%
in stock
$536.00 $375.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA01A4TP
Chemical Name: Promazine hydrochloride
CAS Number: 53-60-1
Molecular Formula: C17H21ClN2S
Molecular Weight: 320.8800
MDL Number: MFCD00058535
SMILES: CN(CCCN1c2ccccc2Sc2c1cccc2)C.Cl
Properties
Complexity: 285  
Covalently-Bonded Unit Count: 2  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 21  
Hydrogen Bond Acceptor Count: 3  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 4  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
Literature fold

Title: Interactions of phenothiazine drugs with bile salts: micellization and binding studies.

Journal: Journal of colloid and interface science20121201

Title: Interaction of amphiphilic drugs with human and bovine serum albumins.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy20121101

Title: Acepromazine pharmacokinetics: a forensic perspective.

Journal: Veterinary journal (London, England : 1997)20121001

Title: Promazine and chlorpromazine for prolonged spinal anesthesia in rats.

Journal: Neuroscience letters20120719

Title: Phase behavior study of amphiphilic drugs: effect of pharmaceutical excipients.

Journal: Colloids and surfaces. B, Biointerfaces20120615

Title: Use of potentiometric sensors to study (bio)molecular interactions.

Journal: Analytical chemistry20120605

Title: Exanthema medicamentosum as a side effect of promazine.

Journal: Psychiatria Danubina20110601

Title: Promazine in the treatment of delusional parasitosis.

Journal: Psychiatria Danubina20110601

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals20101201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters20101101

Title: Broad spectrum drug screening using electron-ionization gas chromatography-mass spectrometry (EI-GCMS).

Journal: Methods in molecular biology (Clifton, N.J.)20100101

Title: Broad spectrum drug screening using liquid chromatography-hybrid triple quadrupole linear ion trap mass spectrometry.

Journal: Methods in molecular biology (Clifton, N.J.)20100101

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology20091001

Title: Simultaneous chemiluminescence determination of promazine and fluphenazine using support vector regression.

Journal: Talanta20090715

Title: Use and misuse of antipsychotic drugs in patients with dementia in Alzheimer special care units.

Journal: International clinical psychopharmacology20090301

Title: Chemiluminescence determination of promazine in human serum and drug formulations using Ru(phen)3(2+)-Ce(IV) system and a chemometrical optimization approach.

Journal: Luminescence : the journal of biological and chemical luminescence20090101

Title: Acute intoxication by triazolam and promazine: a case report.

Journal: Medicine, science, and the law20090101

Title: Validation of derivative spectrophotometry method for determination of active ingredients from neuroleptics in pharmaceutical preparations.

Journal: Acta poloniae pharmaceutica20090101

Title: [Drug-induced agranulocytosis--case reports and literature review].

Journal: Przeglad lekarski20090101

Title: Comparative study of the efficiency of synthetic and natural mediators in laccase-assisted bleaching of eucalyptus kraft pulp.

Journal: Bioresource technology20081101

Title: The cardiorespiratory effects of a fentanyl infusion following acepromazine and glycopyrrolate in dogs.

Journal: Tijdschrift voor diergeneeskunde20081101

Title: The psychotropic drug olanzapine (Zyprexa) increases the area of acid glycerophospholipid monolayers.

Journal: Biophysical chemistry20080401

Title: Modification of the thermal unfolding pathways of myoglobin upon drug interaction in different aqueous media.

Journal: The journal of physical chemistry. B20071213

Title: Thermodynamic studies of drug-alpha-cyclodextrin interactions in water at 298.15 K: promazine hydrochloride/chlorpromazine hydrochloride + alpha-cyclodextrin + H(2)O systems.

Journal: The journal of physical chemistry. B20071206

Title: Synthesis and antitubercular activity of quaternized promazine and promethazine derivatives.

Journal: Bioorganic & medicinal chemistry letters20070301

Title: Drug adverse events and drop-out risk: a clinical case.

Journal: Archives of gerontology and geriatrics20070101

Title: Interactions of recombinant prions with compounds of therapeutical significance.

Journal: Biochemical and biophysical research communications20060602

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology20060501

Title: Relation of postmortem blood alcohol and drug concentrations in fatal poisonings involving amitriptyline, propoxyphene and promazine.

Journal: Human & experimental toxicology20050801

Title: Stability of the tranquilizer drug propionylpromazine hydrochloride in formulated products.

Journal: Pest management science20050601

Title: Acute brain syndrome as a consequence of the Cronkhite-Canada syndrome.

Journal: Psychiatria Danubina20050601

Title: Densitometric high performance thin-layer chromatography identification and quantitative analysis of psychotropic drugs.

Journal: Journal of AOAC International20050101

Title: CSM thioridazine advice.

Journal: The British journal of general practice : the journal of the Royal College of General Practitioners20040801

Title: CSM thioridazine advice.

Journal: The British journal of general practice : the journal of the Royal College of General Practitioners20040801

Title: Old drugs as lead compounds for a new disease? Binding analysis of SARS coronavirus main proteinase with HIV, psychotic and parasite drugs.

Journal: Bioorganic & medicinal chemistry20040515

Title: Comparison of the efficacy of new and conventional antipsychotic drugs in the treatment of behavioral and psychological symptoms of dementia (BPSD).

Journal: Archives of gerontology and geriatrics. Supplement20040101

Title: Contribution of human cytochrome p-450 isoforms to the metabolism of the simplest phenothiazine neuroleptic promazine.

Journal: British journal of pharmacology20030401

Title: Minimal myocardial damage after tricyclic neuroleptic overdose - a case report.

Journal: Pharmacopsychiatry20030101

Title: Influence of classic and atypical neuroleptics on caffeine oxidation in rat liver microsomes.

Journal: Polish journal of pharmacology20030101

Title: Analytical studies and application of reaction of promazine and thioridazine hydrochlorides with some oxidants.

Journal: Acta poloniae pharmaceutica20030101

Title: The contribution of cytochrome P-450 isoenzymes to the metabolism of phenothiazine neuroleptics.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology20021001

Title: Fructose-1,6-diphosphate attenuates acute lung injury induced by ischemia-reperfusion in rats.

Journal: Critical care medicine20020701

Title: Intracellular distribution of psychotropic drugs in the grey and white matter of the brain: the role of lysosomal trapping.

Journal: British journal of pharmacology20011001

Title: Use of laccase together with redox mediators to decolourize Remazol Brilliant Blue R.

Journal: Journal of biotechnology20010823

Title: Application of reinecke salt and alizarin S for the determination of promazine.

Journal: Journal of pharmaceutical and biomedical analysis20010801

Title: [Acute normovolemic hemodilution (ANH). Der Anaesthesist (2000) 49: 939-948].

Journal: Der Anaesthesist20010801

Title: [The opinion of O. Habler].

Journal: Der Anaesthesist20010801

Title: Spectrophotometric determination of vanadium(V) in minerals, steels, soil and biological samples using phenothiazine derivatives.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry20010801

Title: A liquid chromatographic method for the simultaneous determination of promethazine and three of its metabolites in plasma using electrochemical and UV detectors.

Journal: Journal of chromatographic science20010201

Title: Simultaneous quantification of promazine hydrochloride and its sulfoxide in pharmaceutical preparations.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry20010201

Title: Examination of iron (III) and hexacyanoferrate (III) ions as reagents for the spectrophotometric determination of promazine and perazine.

Journal: Acta poloniae pharmaceutica20010101

Title: Effects of xylazine and acetylpromazine upon induced ventricular fibrillation in dogs anesthetized with thiamylal and halothane.

Journal: American journal of veterinary research19750901

Title: Tardive dyskinesia treated with pimozide.

Journal: Journal of the neurological sciences19750401

Title: Neuroleptics and neurologic reactions.

Journal: Southern medical journal19730301

Title: Mutism induced by phenothiazines.

Journal: The British journal of psychiatry : the journal of mental science19721201

Title: Mental disorders caused by isonicotinic acid hydrazide (INH) in the course of treatment of pulmonary tuberculosis.

Journal: Polish medical journal19700101

Title: Phenothiazines in early labour.

Journal: British medical journal19670211

Title: Prolonged apnea after administration of promazine hydrochloride following succinylcholine infusion: a case report.

Journal: Anesthesia and analgesia19670101

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