Name: Name:6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid
Brand: AABLOCKS
SKU: AA003N5M
Rating: 90 (10 reviews)

(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid, commonly known as Trolox, serves as a crucial compound in antioxidant assays. Specifically, it is utilized in the 6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid equivalent antioxidant assay (TEAC) to evaluate the total antioxidant capacity of various fruit species. Trolox's presence in TEAC facilitates the measurement of the antioxidant activity of fruits by comparing their effects with the antioxidant properties of Trolox. This compound plays a pivotal role in assessing and understanding the antioxidant capabilities of different fruits, aiding in nutritional and pharmaceutical research endeavors.

Catalog No.: AA003N5M

53188-07-1 | 6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid

Pack Size： 1mg

Purity： 95%

in stock

$6.00 $4.00

Pack Size： 250mg

Purity： 95%

in stock

$28.00 $19.00

Pack Size： 1g

Purity： 97%

in stock

$42.00 $29.00

Pack Size： 5g

Purity： 95%

in stock

$66.00 $46.00

Pack Size： 10g

Purity： 97%

in stock

$115.00 $80.00

Pack Size： 25g

Purity： 97%

in stock

$250.00 $175.00

Pack Size： 100g

Purity： 97%

in stock

$885.00 $619.00

Quantity

- +

Add to Card

Order Now

bulk Quotation Request

Technical Information

Catalog Number: AA003N5M

Chemical Name: 6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid

CAS Number: 53188-07-1

Molecular Formula: C14H18O4

Molecular Weight: 250.2903

MDL Number: MFCD00006846

SMILES: Cc1c2OC(C)(CCc2c(c(c1C)O)C)C(=O)O

Properties

BP: 450.3°C at 760 mmHg

Form: Solid

MP: 187-189 °C(lit.);

Refractive Index: 1.4970 (estimate)

Storage: Keep in dry area;Room Temperature;

Complexity: 343

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 18

Hydrogen Bond Acceptor Count: 4

Hydrogen Bond Donor Count: 2

Isotope Atom Count: 0

Rotatable Bond Count: 1

Undefined Atom Stereocenter Count: 1

Undefined Bond Stereocenter Count: 0

XLogP3: 2.8

Downstream Synthesis Route

15837-47-5

53188-07-1

6-hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylicacid(6-amino-2,4-dioxo-1-phenyl-1,2,3,4-tetrahydro-pyrimidin-5-yl)-amide

[1]Isobe,Yoshiaki;Tobe,Masanori;Inoue,Yoshifumi;Isobe,Masakazu;Tsuchiya,Masami;Hayashi,Hideya[BioorganicandMedicinalChemistry,2003,vol.11,#23,p.4933-4940]

36653-82-4

53188-07-1

(±)-6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylicacidhexadecylester

[1]CurrentPatentAssignee:SINOBIOPHARMACEUTICALLIMITED-EP2799438,2014,A1Locationinpatent:Paragraph0099-0101

[2]CurrentPatentAssignee:SINOBIOPHARMACEUTICALLIMITED-US2014/343088,2014,A1Locationinpatent:Paragraph0195;0197;0198;0199

[3]Zhang,Xiquan;Cao,Meng;Xing,Jing;Liu,Fei;Dong,Ping;Tian,Xin;Xu,Hongjiang;Zhang,Laifang;Gu,Hongmei;Yang,Ling;Li,Rui;Zheng,Ming;Ji,Min;Gu,Ning[MedicinalChemistryResearch,2017,vol.26,#12,p.3395-3406]

58186-27-9

56305-04-5

3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylicacid10-(4,5-dimethoxy-2-methyl-3,6-dioxo-1,4-cyclohexadien-1-yl)decylester

[1]Molecules,2017,vol.22

343778-59-6

53188-07-1

N-(1-(3-chlorobenzyl)piperidin-4-yl)-6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxamide

[1]Cai,Pei;Fang,Si-Qiang;Yang,Xue-Lian;Wu,Jia-Jia;Liu,Qiao-Hong;Hong,Hao;Wang,Xiao-Bing;Kong,Ling-Yi[ACSChemicalNeuroscience,2017,vol.8,#11,p.2496-2511]

138-14-7

53188-07-1

N1-hydroxy-N-(5-(4-(hydroxy(1-(6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxamido)-1λ5,5λ3-pentyl)amino)-4-oxobutanamido)pentyl)-N4-(5-(N-hydroxyacetamido)pentyl)succinamide

[1]CurrentPatentAssignee:UNIVERSITYOFSYDNEY-WO2017/201581,2017,A1Locationinpatent:Page/Pagecolumn31;32

Application fold

(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid, commonly known as Trolox, serves as a crucial compound in antioxidant assays. Specifically, it is utilized in the 6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid equivalent antioxidant assay (TEAC) to evaluate the total antioxidant capacity of various fruit species. Trolox's presence in TEAC facilitates the measurement of the antioxidant activity of fruits by comparing their effects with the antioxidant properties of Trolox. This compound plays a pivotal role in assessing and understanding the antioxidant capabilities of different fruits, aiding in nutritional and pharmaceutical research endeavors.