Name: Name:(5E)-5-[4-(Dimethylamino)benzylidene]-2-mercapto-1,3-thiazol-4(5h)-one
Brand: AABLOCKS
SKU: AA00I9HF
Rating: 90 (10 reviews)

5-(4-Dimethylaminobenzylidene)rhodanine is a specialized dye with a unique affinity for silver ions, making it particularly useful in various analytical assays. One of its key applications involves quantifying the deposition of silver onto X-ray film in autoradiography experiments, providing researchers with a reliable colorimetric assay for detecting silver-labeled molecules. Additionally, this compound serves as an indicator in the titration of cyanide solution with silver nitrate solution, where it exhibits a distinctive color change in the presence of cyanide ions, facilitating accurate endpoint determination in titration experiments.

Catalog No.: AA00I9HF

536-17-4 | (5E)-5-[4-(Dimethylamino)benzylidene]-2-mercapto-1,3-thiazol-4(5h)-one

Pack Size： 1g

Purity： 92% +(isomers mixture)

in stock

$11.00 $8.00

Pack Size： 5g

Purity： 92% +(isomers mixture)

in stock

$19.00 $13.00

Pack Size： 25g

Purity： 92% +(isomers mixture)

in stock

$39.00 $27.00

Pack Size： 100g

Purity： 92% +(isomers mixture)

in stock

$59.00 $42.00

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Technical Information

Catalog Number: AA00I9HF

Chemical Name: (5E)-5-[4-(Dimethylamino)benzylidene]-2-mercapto-1,3-thiazol-4(5h)-one

CAS Number: 536-17-4

Molecular Formula: C12H12N2OS2

Molecular Weight: 264.3665

MDL Number: MFCD04969049

SMILES: CN(c1ccc(cc1)/C=C\1/SC(=NC1=O)S)C

NSC Number: 5042

Properties

Complexity: 358

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 1

Formal Charge: 0

Heavy Atom Count: 17

Hydrogen Bond Acceptor Count: 4

Hydrogen Bond Donor Count: 1

Isotope Atom Count: 0

Rotatable Bond Count: 2

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 2.9

Downstream Synthesis Route

141-84-4

100-10-7

536-17-4

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[3]Salem,ManarG.;AbdelAziz,YasmineM.;Elewa,Marwa;Nafie,MohamedS.;Elshihawy,HosamA.;Said,MohamedM.[BioorganicChemistry,2021,vol.111]

[4]Locationinpatent:experimentalpartGong,Kai;He,Zhi-Wei;Xu,Ying;Fang,Dong;Liu,Zu-Liang[MonatsheftefurChemie,2008,vol.139,#8,p.913-915]

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[9]Zheng,Qingdong;Yao,Zuguang;Cheng,Jiqi;Shen,Yaochun;Lu,Zuhong[ChemistryLetters,2000,#12,p.1426-1427]

[10]Andreasch;Zipser[MonatsheftefurChemie,1905,vol.26,p.1193]

[11]Bargellini[AttidellaAccademiaNazionaledeiLincei,ClassediScienzeFisiche,MatematicheeNaturali,Rendiconti,1906,vol.<5>15I,p.185][GazzettaChimicaItaliana,1906,vol.36II,p.142]

[12]Lapiere[JournaldePharmaciedeBelgique,<NS>11<1956>3,5,6]

[13]Yaremenko,F.G.etal.[ChemistryofHeterocyclicCompounds,1977,vol.13,p.1190-1194][KhimiyaGeterotsiklicheskikhSoedinenii,1977,vol.13,#11,p.1490-1494]

[14]Ginak,A.I.etal.[JournalofOrganicChemistryUSSR(EnglishTranslation),1971,vol.7,p.1552-1554][ZhurnalOrganicheskoiKhimii,1971,vol.7,p.1500-1502]

[15]Sun,Zhi-Gang;Xu,Yun-Jie;Xu,Jian-Fei;Liu,Qi-Xing;Yang,Yu-Shun;Zhu,Hai-Liang[ChemicalandPharmaceuticalBulletin,2019,vol.67,#2,p.125-129]

536-17-4

99981-54-1

[1]Behringeretal.[ChemischeBerichte,1958,vol.91,p.2773,2783]

536-17-4

857205-41-5

[1]Bhargava;Kulyadi[1958,vol.1,p.29,31]

908094-01-9

536-17-4

28996-10-3

23517-84-2

[1]Ginak,A.I.etal.[JournalofOrganicChemistryUSSR(EnglishTranslation),1970,vol.6,p.1747-1749][ZhurnalOrganicheskoiKhimii,1970,vol.6,p.1744-1746]

141-84-4

1613-99-6

536-17-4

[1]Nederlof,A.[RecueildesTravauxChimiquesdesPays-Bas,1963,vol.82,p.75-89]

Application fold

5-(4-Dimethylaminobenzylidene)rhodanine is a specialized dye with a unique affinity for silver ions, making it particularly useful in various analytical assays. One of its key applications involves quantifying the deposition of silver onto X-ray film in autoradiography experiments, providing researchers with a reliable colorimetric assay for detecting silver-labeled molecules.

Additionally, this compound serves as an indicator in the titration of cyanide solution with silver nitrate solution, where it exhibits a distinctive color change in the presence of cyanide ions, facilitating accurate endpoint determination in titration experiments.