Home Deuterated Building Blocks 536-71-0
536-71-0,MFCD00866606
Catalog No.:AA0039RQ

536-71-0 | 4,4'-(Triaz-1-ene-1,3-diyl)dibenzimidamide

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
99%
2 weeks  
$25.00   $17.00
- +
5g
99%
2 weeks  
$45.00   $32.00
- +
25g
99%
2 weeks  
$119.00   $84.00
- +
100g
99%
2 weeks  
$300.00   $210.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0039RQ
Chemical Name:
4,4'-(Triaz-1-ene-1,3-diyl)dibenzimidamide
CAS Number:
536-71-0
Molecular Formula:
C14H15N7
Molecular Weight:
281.3158
MDL Number:
MFCD00866606
SMILES:
NC(=N)c1ccc(cc1)N/N=N/c1ccc(cc1)C(=N)N
Properties
Computed Properties
 
Complexity:
390  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
5  
XLogP3:
1.9  

Literature

Title: Angiotensin-converting enzyme 2 decreases formation and severity of angiotensin II-induced abdominal aortic aneurysms.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20141201

Title: Is trypanocidal drug resistance a threat for livestock health and production in endemic areas? Food for thoughts from Sahelian goats infected by Trypanosoma vivax in Bobo Dioulasso (Burkina Faso).

Journal: Veterinary parasitology 20121221

Title: Comparative serum biochemical changes induced by experimental infection of T. brucei and T. congolense in pigs.

Journal: Veterinary parasitology 20121221

Title: Ghibe river basin in Ethiopia: present situation of trypanocidal drug resistance in Trypanosoma congolense using tests in mice and PCR-RFLP.

Journal: Veterinary parasitology 20121026

Title: Involvement of mitochondrial genes of Babesia gibsoni in resistance to diminazene aceturate.

Journal: The Journal of veterinary medical science 20120901

Title: Purification of plasmid DNA from clarified and non-clarified Escherichia coli lysates by berenil pseudo-affinity chromatography.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120901

Title: Analysis of energy generation and glycolysis pathway in diminazene aceturate-resistant Babesia gibsoni isolate in vitro.

Journal: The Japanese journal of veterinary research 20120801

Title: Field detection of resistance to isometamidium chloride and diminazene aceturate in Trypanosoma vivax from the region of the Boucle du Mouhoun in Burkina Faso.

Journal: Veterinary parasitology 20120608

Title: The therapeutic efficacy of two antibabesial strategies against Babesia gibsoni.

Journal: Veterinary parasitology 20120525

Title: Modeling the control of trypanosomiasis using trypanocides or insecticide-treated livestock.

Journal: PLoS neglected tropical diseases 20120501

Title: Development of in vitro atovaquone-resistant Babesia gibsoni with a single-nucleotide polymorphism in cytb.

Journal: Veterinary parasitology 20120430

Title: Energetics of ligand binding to the DNA minor groove.

Journal: Physical chemistry chemical physics : PCCP 20120428

Title: Current advances in detection and treatment of babesiosis.

Journal: Current medicinal chemistry 20120401

Title: Quinol derivatives as potential trypanocidal agents.

Journal: Bioorganic & medicinal chemistry 20120215

Title: Diamidinium and iminium aromatics as new aggregators of the bacterial signaling molecule, c-di-GMP.

Journal: Bioorganic & medicinal chemistry letters 20120115

Title: Highly debilitating natural Trypanosoma vivax infections in Brazilian calves: epidemiology, pathology, and probable transplacental transmission.

Journal: Parasitology research 20120101

Title: Comparison of protective immune responses to apicomplexan parasites.

Journal: Journal of parasitology research 20120101

Title: Current State-of-Art and New Trends on Lipid Nanoparticles (SLN and NLC) for Oral Drug Delivery.

Journal: Journal of drug delivery 20120101

Title: Validation of an HPLC method for the simultaneous determination of diminazene diaceturate and phenazone in injectable veterinary granules and bulk powders.

Journal: Pakistan journal of pharmaceutical sciences 20120101

Title: The Trypanosoma cruzi virulence factor oligopeptidase B (OPBTc) assembles into an active and stable dimer.

Journal: PloS one 20120101

Title: How full is our antihypertensives pipeline?

Journal: Journal of pharmacology & pharmacotherapeutics 20120101

Title: Detection of multiple drug-resistant Trypanosoma congolense populations in village cattle of south-east Mali.

Journal: Parasites & vectors 20120101

Title: Biological activities of xanthatin from Xanthium strumarium leaves.

Journal: Phytotherapy research : PTR 20111201

Title: Biodynamic parameters of micellar diminazene in sheep erythrocytes and blood plasma.

Journal: Journal of veterinary science 20111201

Title: High prevalence of drug resistance in animal trypanosomes without a history of drug exposure.

Journal: PLoS neglected tropical diseases 20111201

Title: Susceptibility of mice to Trypanosoma evansi treated with human plasma containing different concentrations of apolipoprotein L-1.

Journal: The Korean journal of parasitology 20111201

Title: Convolutamines I and J, antitrypanosomal alkaloids from the bryozoan Amathia tortusa.

Journal: Bioorganic & medicinal chemistry 20111115

Title: The pharmacological profile of brain liver intestine Na+ channel: inhibition by diarylamidines and activation by fenamates.

Journal: Molecular pharmacology 20111101

Title: Cerebroprotection by angiotensin-(1-7) in endothelin-1-induced ischaemic stroke.

Journal: Experimental physiology 20111001

Title: Managing tsetse transmitted trypanosomosis by insecticide treated nets--an affordable and sustainable method for resource poor pig farmers in Ghana.

Journal: PLoS neglected tropical diseases 20111001

Title: Genital lesions in male red fronted gazelles (Gazella rufifrons) experimentally infected with Trypanosoma brucei and the effect of melarsamine hydrochloride (Cymelarsan®) and diminazene aceturate (Berenil®) in its treatment.

Journal: Theriogenology 20110901

Title: CBFB and MYH11 in inv(16)(p13q22) of acute myeloid leukemia displaying close spatial proximity in interphase nuclei of human hematopoietic stem cells.

Journal: Genes, chromosomes & cancer 20110901

Title: Polyamine homoeostasis as a drug target in pathogenic protozoa: peculiarities and possibilities.

Journal: The Biochemical journal 20110901

Title: Prediction of off-target effects on angiotensin-converting enzyme 2.

Journal: Journal of biomolecular screening 20110901

Title: Melarsoprol cyclodextrin inclusion complexes as promising oral candidates for the treatment of human African trypanosomiasis.

Journal: PLoS neglected tropical diseases 20110901

Title: Serial haematology results in transfused and non-transfused dogs naturally infected with Babesia rossi.

Journal: Journal of the South African Veterinary Association 20110901

Title: Experimental infection with Rangelia vitalii in dogs: acute phase, parasitemia, biological cycle, clinical-pathological aspects and treatment.

Journal: Experimental parasitology 20110801

Title: Polyamines in aging and disease.

Journal: Aging 20110801

Title: Influence of trypanocidal therapy on the haematology of vervet monkeys experimentally infected with Trypanosoma brucei rhodesiense.

Journal: Acta tropica 20110701

Title: Diminazene aceturate associated with sodium selenite and vitamin E in the treatment of Trypanosoma evansi infection in rats.

Journal: Experimental parasitology 20110701

Title: The diamidine diminazene aceturate is a substrate for the high-affinity pentamidine transporter: implications for the development of high resistance levels in trypanosomes.

Journal: Molecular pharmacology 20110701

Title: Improved PCR-RFLP for the detection of diminazene resistance in Trypanosoma congolense under field conditions using filter papers for sample storage.

Journal: PLoS neglected tropical diseases 20110701

Title: Drug delivery systems in the treatment of African trypanosomiasis infections.

Journal: Expert opinion on drug delivery 20110601

Title: SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis.

Journal: PLoS neglected tropical diseases 20110601

Title: Specific berenil-DNA interactions: an approach for separation of plasmid isoforms by pseudo-affinity chromatography.

Journal: Analytical biochemistry 20110515

Title: Effect of topoisomerase inhibitors and DNA-binding drugs on the cell proliferation and ultrastructure of Trypanosoma cruzi.

Journal: International journal of antimicrobial agents 20110501

Title: The effects of combination of methanolic leaf extract of Azadirachta indica and diminazene diaceturate in the treatment of experimental Trypanosoma brucei brucei infection in rats.

Journal: Asian Pacific journal of tropical medicine 20110501

Title: Horses naturally infected by Trypanosoma vivax in southern Brazil.

Journal: Parasitology research 20110101

Title: Synthesis and antitrypanosomal evaluation of derivatives of N-benzyl-1,2-dihydroquinolin-6-ols: Effect of core substitutions and salt formation.

Journal: Bioorganic & medicinal chemistry 20110101

Title: Emergence of new types of Theileria orientalis in Australian cattle and possible cause of theileriosis outbreaks.

Journal: Parasites & vectors 20110101

Title: Efficacy study of novel diamidine compounds in a Trypanosoma evansi goat model.

Journal: PloS one 20110101

Title: Molecular and cellular characterization of an AT-hook protein from Leishmania.

Journal: PloS one 20110101

Title: In vitro and in vivo antileishmanial efficacy of a combination therapy of diminazene and artesunate against Leishmania donovani in BALB/c mice.

Journal: Revista do Instituto de Medicina Tropical de Sao Paulo 20110101

Title: Functional modifications of acid-sensing ion channels by ligand-gated chloride channels.

Journal: PloS one 20110101

Title: Neglected disease - african sleeping sickness: recent synthetic and modeling advances.

Journal: Scientia pharmaceutica 20110101

Title: Experimental Chemotherapy for Chagas Disease: A Morphological, Biochemical, and Proteomic Overview of Potential Trypanosoma cruzi Targets of Amidines Derivatives and Naphthoquinones.

Journal: Molecular biology international 20110101

Title: Gold nanoparticles in biology and medicine: recent advances and prospects.

Journal: Acta naturae 20110101

Title: Development of a nanoparticulate formulation of diminazene to treat African trypanosomiasis.

Journal: Nanotechnology 20101217

Title: Crystal structure of Leishmania major oligopeptidase B gives insight into the enzymatic properties of a trypanosomatid virulence factor.

Journal: The Journal of biological chemistry 20101210

Title: The killing of African trypanosomes by ethidium bromide.

Journal: PLoS pathogens 20101201

Title: Reduced transcript levels of the heat shock protein 70 gene in diminazene aceturate-resistant Babesia gibsoni variants under low concentrations of diminazene aceturate.

Journal: The Japanese journal of veterinary research 20101101

Title: Babesia canis and Babesia rossi co-infection in an untraveled Nigerian dog.

Journal: Veterinary parasitology 20101029

Title: Chemosensitization of Trypanosoma congolense strains resistant to isometamidium chloride by tetracyclines and enrofloxacin.

Journal: PLoS neglected tropical diseases 20100901

Title: Efficacy of Cymelarsan and Diminasan against Trypanosoma equiperdum infections in mice and horses.

Journal: Veterinary parasitology 20100804

Title: Malaria gametocytogenesis.

Journal: Molecular and biochemical parasitology 20100801

Title: Selective delivery of 2-hydroxy APA to Trypanosoma brucei using the melamine motif.

Journal: Bioorganic & medicinal chemistry letters 20100801

Title: Trypanosoma vivax infections: pushing ahead with mouse models for the study of Nagana. I. Parasitological, hematological and pathological parameters.

Journal: PLoS neglected tropical diseases 20100801

Title: DNA instability at chromosomal fragile sites in cancer.

Journal: Current genomics 20100801

Title: Diarylamidines: high potency inhibitors of acid-sensing ion channels.

Journal: Neuropharmacology 20100601

Title: Development and characterization of a strain of Babesia gibsoni resistant to diminazene aceturate in vitro.

Journal: The Journal of veterinary medical science 20100601

Title: Structural binding evidence of the trypanocidal drugs berenil and pentacarinate active principles to a serine protease model.

Journal: International journal of biological macromolecules 20100601

Title: In vitro activity and preliminary toxicity of various diamidine compounds against Trypanosoma evansi.

Journal: Veterinary parasitology 20100511

Title: Curcuminoid analogs with potent activity against Trypanosoma and Leishmania species.

Journal: European journal of medicinal chemistry 20100301

Title: Frequency and therapy monitoring of canine Babesia spp. infection by high-resolution melting curve quantitative FRET-PCR.

Journal: Veterinary parasitology 20100226

Title: Antitrypanosomal activity of 1,2-dihydroquinolin-6-ols and their ester derivatives.

Journal: Journal of medicinal chemistry 20100211

Title: Multiple genetic mechanisms lead to loss of functional TbAT1 expression in drug-resistant trypanosomes.

Journal: Eukaryotic cell 20100201

Title: Evaluation of the in vitro growth-inhibitory effect of epoxomicin on Babesia parasites.

Journal: Veterinary parasitology 20100120

Title: Characterization of major surface protease homologues of Trypanosoma congolense.

Journal: Journal of biomedicine & biotechnology 20100101

Title: Immunobiology of African trypanosomes: need of alternative interventions.

Journal: Journal of biomedicine & biotechnology 20100101

Title: Multifunctional Nanocarriers for diagnostics, drug delivery and targeted treatment across blood-brain barrier: perspectives on tracking and neuroimaging.

Journal: Particle and fibre toxicology 20100101

Title: Proteomics of Trypanosoma evansi infection in rodents.

Journal: PloS one 20100101

Title: Use of a doxycycline-enrofloxacin-metronidazole combination with/without diminazene diaceturate to treat naturally occurring canine babesiosis caused by Babesia gibsoni.

Journal: Acta veterinaria Scandinavica 20100101

Title: Distamycin A inhibits HMGA1-binding to the P-selectin promoter and attenuates lung and liver inflammation during murine endotoxemia.

Journal: PloS one 20100101

Title: Experiences with an in-training community service model in the control of zoonotic sleeping sickness in Uganda.

Journal: Journal of veterinary medical education 20100101

Title: The effect of a novel dinuclear platinum complex with berenil and 2-picoline ligands on growth of human breast cancer cells.

Journal: Acta poloniae pharmaceutica 20100101

Title: Senna occidentalis leaf extract possesses antitrypanosomal activity and ameliorates the trypanosome-induced anemia and organ damage.

Journal: Pharmacognosy research 20100101

Title: The intravenous pharmacokinetics of diminazene in healthy dogs.

Journal: Journal of the South African Veterinary Association 20091201

Title: The effects of hairpin loops on ligand-DNA interactions.

Journal: The journal of physical chemistry. B 20091029

Title: Diminazene aceturate in the control of Trypanosoma evansi infection in cats.

Journal: Veterinary parasitology 20091028

Title: Structure and inhibition of human diamine oxidase.

Journal: Biochemistry 20091020

Title: Endemic type of animal trypanosomiasis is not associated with lower genotype variability of Trypanosoma congolense isolates circulating in livestock.

Journal: Research in veterinary science 20091001

Title: Development of an Alamar Blue viability assay in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427.

Journal: The American journal of tropical medicine and hygiene 20091001

Title: Genotypic status of the TbAT1/P2 adenosine transporter of Trypanosoma brucei gambiense isolates from Northwestern Uganda following melarsoprol withdrawal.

Journal: PLoS neglected tropical diseases 20090901

Title: Advancing drug innovation for neglected diseases-criteria for lead progression.

Journal: PLoS neglected tropical diseases 20090801

Title: Effects of melarsamine hydrochloride (Cymelarsan) and diminazene aceturate (Berenil) on the pathology of experimental Trypanosoma brucei infection in red fronted gazelles (Gazella rufifrons).

Journal: Veterinary parasitology 20090707

Title: Immunospecific immunoglobulins and IL-10 as markers for Trypanosoma brucei rhodesiense late stage disease in experimentally infected vervet monkeys.

Journal: Tropical medicine & international health : TM & IH 20090701

Title: Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis.

Journal: Brain : a journal of neurology 20090501

Title: Isolation of antibabesial compounds from Brucea javanica, Curcuma xanthorrhiza, and Excoecaria cochinchinensis.

Journal: Bioscience, biotechnology, and biochemistry 20090323

Title: Evaluation of efficacy of bruceine A, a natural quassinoid compound extracted from a medicinal plant, Brucea javanica, for canine babesiosis.

Journal: The Journal of veterinary medical science 20090101

Title: Canine babesiosis: from molecular taxonomy to control.

Journal: Parasites & vectors 20090101

Title: Chemotherapy of human african trypanosomiasis.

Journal: Interdisciplinary perspectives on infectious diseases 20090101

Title: A luciferase based viability assay for ATP detection in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427.

Journal: Parasites & vectors 20090101

Title: In vitro antitrypanosomal activities of quassinoid compounds from the fruits of a medicinal plant, Brucea javanica.

Journal: Veterinary parasitology 20081220

Title: Pharmacophore based discovery of potential antimalarial agent targeting haem detoxification pathway.

Journal: European journal of medicinal chemistry 20081201

Title: Five-fold increase in Trypanosoma congolense isolates resistant to diminazene aceturate over a seven-year period in Eastern Zambia.

Journal: Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20081201

Title: The blood-brain barrier significantly limits eflornithine entry into Trypanosoma brucei brucei infected mouse brain.

Journal: Journal of neurochemistry 20081101

Title: Preparation of polyclonal antibodies to diminazene and its detection in animal blood plasma.

Journal: International immunopharmacology 20081001

Title: The promotion of secondary structures in single-stranded DNA by drugs that bind to duplex DNA: an atomic force microscopy study.

Journal: Nanotechnology 20080924

Title: Estimation of tsetse challenge and its relationship with trypanosomosis incidence in cattle kept under pastoral production systems in Kenya.

Journal: Veterinary parasitology 20080817

Title: Comparative efficacy of diminazene diaceturate and diminazene aceturate for the treatment of babesiosis in horses.

Journal: Tropical animal health and production 20080801

Title: Enhancement of hydrophilic drug loading and release characteristics through micellization with new carboxymethyldextran-PEG block copolymers of tunable charge density.

Journal: International journal of pharmaceutics 20080522

Title: Assessment of the occurrence of trypanocidal drug resistance in trypanosomes of naturally infected cattle in the Adamaoua region of Cameroon using the standard mouse test and molecular tools.

Journal: Acta tropica 20080501

Title: Molecular tools for the rapid detection of drug resistance in animal trypanosomes.

Journal: Trends in parasitology 20080501

Title: Prevalence of bovine trypanosomosis and trypanocidal drug sensitivity studies on Trypanosoma congolense in Wolyta and Dawero zones of southern Ethiopia.

Journal: Veterinary parasitology 20080325

Title: Comparative efficacy assessment of pentamidine isethionate and diminazene aceturate in the chemotherapy of Trypanosoma brucei brucei infection in dogs.

Journal: Veterinary parasitology 20080214

Title: Development of potent purine-derived nitrile inhibitors of the trypanosomal protease TbcatB.

Journal: Journal of medicinal chemistry 20080214

Title: Acute phase response in mice experimentally infected with Trypanosoma congolense: a molecular gauge of parasite-host interaction.

Journal: Veterinary parasitology 20080125

Title: Microarray analysis of the in vivo sequence preferences of a minor groove binding drug.

Journal: BMC genomics 20080101

Title: DNA-binding activity and cytotoxicity of Pt-berenil compounds in MDA-MB-231 and MCF-7 breast cancer cells.

Journal: Acta poloniae pharmaceutica 20080101

Title: Synthesis, DNA-binding affinity and cytotoxicity of the dinuclear platinum(II) complexes with berenil and amines ligands.

Journal: Acta poloniae pharmaceutica 20080101

Title: A systematic approach to understand the mechanism of action of the bisthiazolium compound T4 on the human malaria parasite, Plasmodium falciparum.

Journal: BMC genomics 20080101

Title: Screening of Indonesian medicinal plant extracts for antibabesial activity and isolation of new quassinoids from Brucea javanica.

Journal: Journal of natural products 20071001

Title: Heterogeneity in the trypanosomosis incidence in Zebu cattle of different ages and sex on the plateau of eastern Zambia.

Journal: Acta tropica 20070801

Title: Clinical management of babesiosis in dogs with homeopathic Crotalus horridus 200C.

Journal: Homeopathy : the journal of the Faculty of Homeopathy 20070401

Title: Anti-babesial compounds from Curcuma xanthorrhiza.

Journal: Natural product research 20070401

Title: Molecular characterisation of Babesia gibsoni infection from a pit-bull terrier pup recently imported into South Africa.

Journal: Journal of the South African Veterinary Association 20070301

Title: Occurrence of multiple drug resistance in Trypanosoma brucei rhodesiense isolated from sleeping sickness patients.

Journal: The Onderstepoort journal of veterinary research 20070301

Title: The pathogenesis of anaemia in goats experimentally infected with Trypanosoma congolense or Trypanosoma brucei: use of the myeloid:erythroid ratio.

Journal: Veterinary parasitology 20070227

Title: Rigid dipeptide mimics: synthesis of enantiopure C6-functionalized pyrrolizidinone amino acids.

Journal: The Journal of organic chemistry 20070202

Title: Trypanosomiasis by Trypanosoma vivax in cattle in the Brazilian semiarid: Description of an outbreak and lesions in the nervous system.

Journal: Veterinary parasitology 20070131

Title: Co-administration of Na-EDTA and diminazene aceturate (DA) to mice infected with DA-resistant Trypanosoma brucei.

Journal: Journal of comparative pathology 20070101

Title: Genotypic and phenotypic characterization of Trypanosoma brucei gambiense isolates from Ibba, South Sudan, an area of high melarsoprol treatment failure rate.

Journal: Acta tropica 20070101

Title: Combined contribution of TbAT1 and TbMRPA to drug resistance in Trypanosoma brucei.

Journal: Molecular and biochemical parasitology 20061201

Title: Androgens differentially potentiate mouse intestinal smooth muscle by nongenomic activation of polyamine synthesis and Rho kinase activation.

Journal: Endocrinology 20061201

Title: Fumagillin, a new P-glycoprotein-interfering agent able to modulate moxidectin efflux in rat hepatocytes.

Journal: Journal of veterinary pharmacology and therapeutics 20061201

Title: Confirmation of diminazene diaceturate in bovine plasma using electrospray liquid chromatography-mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061121

Title: SSCP analysis of the P2 purine transporter TcoAT1 gene of Trypanosoma congolense leads to a simple PCR-RFLP test allowing the rapid identification of diminazene resistant stocks.

Journal: Acta tropica 20061101

Title: Response of four indigenous cattle breeds to natural tsetse and trypanosomosis challenge in the Ghibe valley of Ethiopia.

Journal: Veterinary parasitology 20061010

Title: Porcine eperythrozoonosis in China.

Journal: Annals of the New York Academy of Sciences 20061001

Title: Equine trypanosomosis in the Central River Division of The Gambia: a study of veterinary gate-clinic consultation records.

Journal: Preventive veterinary medicine 20060817

Title: Stability analysis for double-stranded DNA oligomers and their noncovalent complexes with drugs by laser spray.

Journal: Journal of mass spectrometry : JMS 20060801

Title: Excitability scores of goats administered ascorbic acid and transported during hot-dry conditions.

Journal: Journal of veterinary science 20060601

Title: Chemotherapy against babesiosis.

Journal: Veterinary parasitology 20060531

Title: Epidemiology of Trypanosoma vivax infection in cattle in the tse-tse free area of Lake Chad.

Journal: Preventive veterinary medicine 20060517

Title: Study on the susceptibility of Sahel goats to experimental Trypanosoma vivax infection.

Journal: Veterinary parasitology 20060430

Title: Quantitative analysis of DNA-porphyrin interactions.

Journal: Biopolymers 20060405

Title: Complexes of poly(ethylene oxide)-block-poly(L-glutamate) and diminazene.

Journal: Langmuir : the ACS journal of surfaces and colloids 20060227

Title: Drug-resistance of Trypanosoma b. rhodesiense isolates from Tanzania.

Journal: Tropical medicine & international health : TM & IH 20060201

Title: Leishmania donovani: differential activities of classical topoisomerase inhibitors and antileishmanials against parasite and host cells at the level of DNA topoisomerase I and in cytotoxicity assays.

Journal: Experimental parasitology 20060101

Title: A diminazene-resistant strain of Trypanosoma brucei brucei isolated from a dog is cross-resistant to pentamidine in experimentally infected albino rats.

Journal: Parasitology 20060101

Title: RNA aptamers as potential pharmaceuticals against infections with African trypanosomes.

Journal: Handbook of experimental pharmacology 20060101

Title: The effectivity analysis of accumulation of liposomal, micellar, and water-soluble forms of diminazene in cells and in organs.

Journal: Drug delivery 20060101

Title: In vitro growth inhibition of bloodstream forms of Trypanosoma brucei and Trypanosoma congolense by iron chelators.

Journal: Kinetoplastid biology and disease 20060101

Title: Comparative application of wavelet approaches to absorption and ratio spectra for the simultaneous determination of diminazene aceturate and phenazone in veterinary granules for injection.

Journal: Die Pharmazie 20051201

Title: The susceptibility of Trypanosoma congolense isolated in Zambézia Province, Mozambique, to isometamidium chloride, diminazene aceturate and homidium chloride.

Journal: The Onderstepoort journal of veterinary research 20051201

Title: Acquired resistance to berenil in a cloned isolate of Trypanosoma evansi is associated with upregulation of a novel gene, TeDR40.

Journal: Parasitology 20051101

Title: Thermodynamic evaluation and modeling of proton and water exchange associated with benzamidine and berenil binding to beta-trypsin.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20051101

Title: Diminazene aceturate resistance on the virulence of Trypanosoma brucei for rats.

Journal: Journal of comparative pathology 20051101

Title: The pharmacokinetics of diminazene aceturate after intramuscular administration in healthy dogs.

Journal: Journal of the South African Veterinary Association 20050901

Title: Synthesis of a novel PEG-block-poly(aspartic acid-stat-phenylalanine) copolymer shows potential for formation of a micellar drug carrier.

Journal: International journal of pharmaceutics 20050613

Title: Susceptibility of West African Dwarf goats and WAD x Saanen crosses to experimental infection with Trypanosoma congolense.

Journal: Veterinary parasitology 20050610

Title: Identification of anti-babesial activity for four ethnoveterinary plants in vitro.

Journal: Veterinary parasitology 20050610

Title: Anti-babesial compounds from Curcuma zedoaria.

Journal: Planta medica 20050501

Title: Semicarbazide-functionalized Si(111) surfaces for the site-specific immobilization of peptides.

Journal: Langmuir : the ACS journal of surfaces and colloids 20050215

Title: Exotic diseases of dogs and cats at risk of importation to Ireland.

Journal: Irish veterinary journal 20050101

Title: Transition models to assess risk factors for new and persistent trypanosome infections in cattle-analysis of longitudinal data from the Ghibe Valley, southwest Ethiopia.

Journal: The Journal of parasitology 20041201

Title: Knowledge and attitudes of cattle owners regarding trypanosomosis control in tsetse-infested areas of Uganda.

Journal: Journal of the South African Veterinary Association 20041201

Title: Analysis of GAA/TTC DNA triplexes using nuclear magnetic resonance and electrospray ionization mass spectrometry.

Journal: Analytical biochemistry 20041115

Title: Degradation of berenil (diminazene aceturate) in acidic aqueous solution.

Journal: The Journal of pharmacy and pharmacology 20041001

Title: Trypanocidal failure suggested by PCR results in cattle field samples.

Journal: Acta tropica 20040901

Title: Protective efficacy of isometamidium chloride and diminazene aceturate against natural Trypanosoma brucei, Trypanosoma congolense and Trypanosoma vivax infections in cattle under a suppressed tsetse population in Uganda.

Journal: The Onderstepoort journal of veterinary research 20040901

Title: DNA minor groove binders as potential antitumor and antimicrobial agents.

Journal: Medicinal research reviews 20040701

Title: Micronuclei induced by aneugens and clastogens in mononucleate and binucleate cells using the cytokinesis block assay.

Journal: Mutagenesis 20040701

Title: Effect of diminazene block treatment on live redwater vaccine reactions.

Journal: The Onderstepoort journal of veterinary research 20040601

Title: Lipid-drug conjugate nanoparticles of the hydrophilic drug diminazene-cytotoxicity testing and mouse serum adsorption.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20040518

Title: Bloodstream form-specific up-regulation of silent vsg expression sites and procyclin in Trypanosoma brucei after inhibition of DNA synthesis or DNA damage.

Journal: The Journal of biological chemistry 20040402

Title: Application of field methods to assess isometamidium resistance of trypanosomes in cattle in western Ethiopia.

Journal: Acta tropica 20040401

Title: Characterization of a novel DNA minor-groove complex.

Journal: Biophysical journal 20040201

Title: Trypanocidal drug resistance in eastern province of Zambia.

Journal: Veterinary parasitology 20040130

Title: The effects of diminazene aceturate and ceftriaxone on ram sperm.

Journal: Theriogenology 20040115

Title: A large-scale trial to evaluate the efficacy of a 1% pour-on formulation of cyfluthrin (Cylence, Bayer) in controlling bovine trypanosomosis in Eastern Zambia.

Journal: Tropical animal health and production 20040101

Title: RNA-interference silencing of the adenosine transporter-1 gene in Trypanosoma evansi confers resistance to diminazene aceturate.

Journal: Experimental parasitology 20040101

Title: Gametocytogenesis: the puberty of Plasmodium falciparum.

Journal: Malaria journal 20040101

Title: Efficacy of combined atovaquone and azithromycin for therapy of chronic Babesia gibsoni (Asian genotype) infections in dogs.

Journal: Journal of veterinary internal medicine 20040101

Title: Efficacy of Trypan: a diminazene based drug as antileishmanial agent.

Journal: Acta tropica 20040101

Title: The effect of inducing agents on the metabolism of trypanocidal diamidines by isolated rat hepatocytes.

Journal: Chemico-biological interactions 20031215

Title: Changes in adenosine transport associated with melaminophenyl arsenical (Mel CY) resistance in Trypanosoma evansi: down-regulation and affinity changes of the P2 transporter.

Journal: Parasitology 20031201

Title: The leucocytic and parasitaemic profiles and immune response of rats treated with retinyl palmitate before infection with Trypanosoma brucei.

Journal: Journal of comparative pathology 20031101

Title: Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei.

Journal: Eukaryotic cell 20031001

Title: The effects of diminazene aceturate on systemic blood pressure in clinically healthy adult dogs.

Journal: Journal of the South African Veterinary Association 20030901

Title: Clinical and neuroinflammatory responses to meningoencephalitis in substance P receptor knockout mice.

Journal: Brain : a journal of neurology 20030701

Title: Field studies of drug-resistant cattle trypanosomes in Kénédougou Province, Burkina Faso.

Journal: Acta tropica 20030401

Title: Intra-uterine Infection with Babesia bovis in a 2-day-old Calf.

Journal: Journal of veterinary medicine. B, Infectious diseases and veterinary public health 20030301

Title: Chemotherapy of surra in horses and mules with diminazene aceturate.

Journal: Veterinary parasitology 20030102

Title: The pathogenicity of diminazene aceturate-resistant Trypanosoma brucei in rats after treatment with the drug.

Journal: Journal of comparative pathology 20030101

Title: The rare human fragile site 16B.

Journal: Cytogenetic and genome research 20030101

Title: Liquid chromatographic determination of diminazene diaceturate (Berenil) in raw bovine milk.

Journal: Journal of AOAC International 20030101

Title: Electron paramagnetic resonance dynamic signatures of TAR RNA-small molecule complexes provide insight into RNA structure and recognition.

Journal: Biochemistry 20021217

Title: Determination of diminazene aceturate in pharmaceutical formulations by HPLC and identification of related substances by LC/MS.

Journal: Journal of pharmaceutical and biomedical analysis 20021107

Title: A competitive enzyme-linked immunosorbent assay for diminazene.

Journal: Acta tropica 20021101

Title: Financial implications of rearing sheep and goats under natural trypanosomosis challenge at Galana ranch, Kenya.

Journal: Tropical animal health and production 20021101

Title: Residual effect of antibabesial drugs on the live redwater blood vaccines.

Journal: Annals of the New York Academy of Sciences 20021001

Title: Drug sensitivity of trypanosome populations from cattle in a peri-urban dairy production system in Uganda.

Journal: Acta tropica 20021001

Title: Lipid-drug-conjugate (LDC) nanoparticles as novel carrier system for the hydrophilic antitrypanosomal drug diminazenediaceturate.

Journal: Journal of drug targeting 20020801

Title: In vitro cultivation of Chinese strains of Babesia spp.

Journal: Parasitology research 20020501

Title: Developments in the treatment of leishmaniasis and trypanosomiasis.

Journal: Expert opinion on emerging drugs 20020501

Title: Screening of acyl hydrazide proteinase inhibitors for antiparasitic activity against Trypanosoma brucei.

Journal: International journal of antimicrobial agents 20020301

Title: Inhibition of DNA replication by berenil in plasmids containing Poly(dA)poly(dT) sequences.

Journal: Plasmid 20020301

Title: S-adenosylmethionine decarboxylase from Leishmania donovani. Molecular, genetic, and biochemical characterization of null mutants and overproducers.

Journal: The Journal of biological chemistry 20020222

Title: Effect of strand orientation on the interaction of berenil with DNA triple helices.

Journal: European biophysics journal : EBJ 20020201

Title: Discriminating small molecule DNA binding modes by single molecule force spectroscopy.

Journal: FEBS letters 20020116

Title: Inhibition of DNA replication by berenil of bacterial plasmids containing poly(dA)-poly(dT) sequences. 2D gel analysis of replicative intermediates.

Journal: Cellular and molecular biology (Noisy-le-Grand, France) 20020101

Title: Changes in properties of adenosine transporters in Trypanosoma evansi and modes of selection of resistance to the melaminophenyl arsenical drug, Mel Cy.

Journal: Veterinary parasitology 20011213

Title: Enhancing effects of anti-CD40 treatment on the immune response of SCID-bovine mice to Trypanosoma congolense infection.

Journal: Journal of leukocyte biology 20011201

Title: In vitro effect of alkaloids on bloodstream forms of Trypanosoma brucei and T. congolense.

Journal: Planta medica 20011001

Title: Drug-resistant Trypanosoma congolense in naturally infected donkeys in north Omo Zone, southern Ethiopia.

Journal: Veterinary parasitology 20010831

Title: Drug-polyionic block copolymer interactions for micelle formation: physicochemical characterisation.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20010810

Title: Bioassay-guided studies on the cytotoxic and in vitro trypanocidal activities of a sesquiterpene (Muzigadial) derived from a Ugandan medicinal plant (Warburgia ugandensis).

Journal: African health sciences 20010801

Title: Heterogeneous DNA binding modes of berenil.

Journal: Biochimica et biophysica acta 20010628

Title: A simple, high-resolution method for establishing DNA binding affinity and sequence selectivity.

Journal: Journal of the American Chemical Society 20010627

Title: Standardised tests in mice and cattle for the detection of drug resistance in tsetse-transmitted trypanosomes of African domestic cattle.

Journal: Veterinary parasitology 20010612

Title: Concentration-dependent inhibition of sheep erythrocyte ghost plasma membrane Ca2+-ATPase activity by Berenil.

Journal: Journal of veterinary pharmacology and therapeutics 20010601

Title: DNA minor-groove recognition by small molecules.

Journal: Natural product reports 20010601

Title: The incidence of new and the prevalence and persistence of recurrent trypanosome infections in cattle in southwest Ethiopia exposed to a high challenge with drug-resistant parasites.

Journal: Acta tropica 20010525

Title: A comparative evaluation of parasitological tests and a PCR for Trypanosoma evansi diagnosis in experimentally infected water buffaloes.

Journal: Veterinary parasitology 20010509

Title: Transporters in African trypanosomes: role in drug action and resistance.

Journal: International journal for parasitology 20010501

Title: Effect of clindamycin therapy on phagocytic and oxidative activity profiles of spleen mononuclear cells in Babesia rodhaini-infected mice.

Journal: The Journal of veterinary medical science 20010501

Title: Validation of a polymerase chain reaction assay for monitoring the therapeutic efficacy of diminazene aceturate in trypanosome-infected sheep.

Journal: Veterinary parasitology 20010320

Title: Uptake of pentamidine in Trypanosoma brucei brucei is mediated by three distinct transporters: implications for cross-resistance with arsenicals.

Journal: Molecular pharmacology 20010301

Title: Cytokines and the acute phase response in post-treatment reactive encephalopathy of Trypanosoma brucei brucei infected mice.

Journal: Parasitology international 20010301

Title: Enhanced lipid peroxide levels in the erythrocytes of calves with haemoglobinuria.

Journal: Veterinary research communications 20010101

Title: In vitro effect of diamidines on intracellular polyamines of Acanthamoeba polyphaga.

Journal: Drugs under experimental and clinical research 20010101

Title: Highly potent synthetic polyamides, bisdistamycins, and lexitropsins as inhibitors of human immunodeficiency virus type 1 integrase.

Journal: Molecular pharmacology 19980801

Title: Linked lexitropsins and the in vitro inhibition of HIV-1 reverse transcriptase RNA-directed DNA polymerization: a novel induced-fit of 3,5 m-pyridyl bisdistamycin to enzyme-associated template-primer.

Journal: Biochemistry 19961203

Title: Efficacy of 101 antimicrobials and other agents on the development of Cryptosporidium parvum in vitro.

Journal: Annals of tropical medicine and parasitology 19961201

Title: New drug developments for opportunistic infections in immunosuppressed patients: Pneumocystis carinii.

Journal: Journal of medicinal chemistry 19951124

Title: DNA-binding activity and biological effects of aromatic polyamidines.

Journal: Biochemical pharmacology 19940211

Title: Efficacy of DL-alpha-difluoromethylornithine in a rat model of Pneumocystis carinii pneumonia.

Journal: Antimicrobial agents and chemotherapy 19880801

Title: Cationic antitrypanosomal and other antimicrobial agents in the therapy of experimental Pneumocystis carinii pneumonia.

Journal: Antimicrobial agents and chemotherapy 19880601

Title: Antifungal and antibacterial activities of diarylamidine derivatives.

Journal: Antimicrobial agents and chemotherapy 19800801

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:536-71-0 Molecular Formula|536-71-0 MDL|536-71-0 SMILES|536-71-0 4,4'-(Triaz-1-ene-1,3-diyl)dibenzimidamide