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54-36-4,MFCD00006397
Catalog No.:AA00D9O4

54-36-4 | METYRAPONE

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1mg
95%
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$7.00   $5.00
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5mg
95%
in stock  
$14.00   $10.00
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25mg
95%
in stock  
$25.00   $18.00
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100mg
95%
in stock  
$36.00   $25.00
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250mg
≥98%
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$36.00   $25.00
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500mg
≥98%
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1g
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00D9O4
Chemical Name:
METYRAPONE
CAS Number:
54-36-4
Molecular Formula:
C14H14N2O
Molecular Weight:
226.2738
MDL Number:
MFCD00006397
SMILES:
O=C(C(c1cccnc1)(C)C)c1cccnc1
Properties
Properties
 
BP:
384.4°C at 760 mmHg  
Form:
Solid  
MP:
48-51ºC  
Storage:
Room Temperature;Inert atmosphere;  

Computed Properties
 
Complexity:
275  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
3  
Rotatable Bond Count:
3  
XLogP3:
2  

Literature

Title: Ozone Inhalation Provokes Glucocorticoid-Dependent and -Independent Effects on Inflammatory and Metabolic Pathways.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20160701

Title: Therapy of endocrine disease: steroidogenesis enzyme inhibitors in Cushing's syndrome.

Journal: European journal of endocrinology 20150601

Title: Biochemical properties of human dehydrogenase/reductase (SDR family) member 7.

Journal: Chemico-biological interactions 20140125

Title: A reappraisal of the medical therapy with steroidogenesis inhibitors in Cushing's syndrome.

Journal: Clinical endocrinology 20121101

Title: The use of an early postoperative CRH test to assess adrenal function after transsphenoidal surgery for pituitary adenomas.

Journal: Pituitary 20120901

Title: Effects of the combination of metyrapone and oxazepam on intravenous nicotine self-administration in rats.

Journal: Psychopharmacology 20120901

Title: Medical management of Cushing's disease: what is the future?

Journal: Pituitary 20120901

Title: Acute stress-induced sensitization of the pituitary-adrenal response to heterotypic stressors: independence of glucocorticoid release and activation of CRH1 receptors.

Journal: Hormones and behavior 20120901

Title: Screening for modulatory effects on steroidogenesis using the human H295R adrenocortical cell line: a metabolomics approach.

Journal: Chemical research in toxicology 20120820

Title: Novel imidazol-1-ylmethyl substituted 1,2,5,6-tetrahydropyrrolo[3,2,1-ij]quinolin-4-ones as potent and selective CYP11B1 inhibitors for the treatment of Cushing's syndrome.

Journal: Journal of medicinal chemistry 20120726

Title: Effects of the combination of metyrapone and oxazepam on cocaine craving and cocaine taking: a double-blind, randomized, placebo-controlled pilot study.

Journal: Journal of psychopharmacology (Oxford, England) 20120701

Title: Role of the pituitary–adrenal axis in granulocyte-colony stimulating factor-induced neuroprotection against hypoxia–ischemia in neonatal rats.

Journal: Neurobiology of disease 20120701

Title: Assessment of central adrenal insufficiency in children and adolescents with Prader-Willi syndrome.

Journal: Clinical endocrinology 20120601

Title: Pathophysiology of hypercortisolism in depression: pituitary and adrenal responses to low glucocorticoid feedback.

Journal: Acta psychiatrica Scandinavica 20120601

Title: An ectopic ACTH-producing small cell lung carcinoma associated with enhanced corticosteroid biosynthesis in the peritumoral areas of adrenal metastasis.

Journal: Lung cancer (Amsterdam, Netherlands) 20120601

Title: Consequences of acute stress and cortisol manipulation on the physiology, behavior, and reproductive outcome of female Pacific salmon on spawning grounds.

Journal: Hormones and behavior 20120601

Title: Metyrapone effects on systemic and cerebral energy metabolism.

Journal: European journal of pharmacology 20120505

Title: Risk assessment behaviors associated with corticosterone trigger the defense reaction to social isolation in rats: role of the anterior cingulate cortex.

Journal: Stress (Amsterdam, Netherlands) 20120501

Title: Taenia crassiceps WFU cysticerci synthesize corticosteroids in vitro: metyrapone regulates the production.

Journal: General and comparative endocrinology 20120501

Title: Role of corticotropin-releasing factor and corticosterone in behavioral sensitization to ethanol.

Journal: The Journal of pharmacology and experimental therapeutics 20120501

Title: ACTH-induced cortisol release is related to the copy number of the C4B gene encoding the fourth component of complement in patients with non-functional adrenal incidentaloma.

Journal: Clinical endocrinology 20120401

Title: Role of neurosteroids in the anticonvulsant activity of midazolam.

Journal: British journal of pharmacology 20120401

Title: Standardized LC-MS/MS based steroid hormone profile-analysis.

Journal: The Journal of steroid biochemistry and molecular biology 20120401

Title: Increases of CRF in the amygdala are responsible for reinstatement of methamphetamine-seeking behavior induced by footshock.

Journal: Pharmacology, biochemistry, and behavior 20120401

Title: Corticotroph deficiency.

Journal: Annales d'endocrinologie 20120401

Title: [Recent progress in the treatment of Cushing's disease].

Journal: Annales d'endocrinologie 20120401

Title: Computational prediction of metabolism: sites, products, SAR, P450 enzyme dynamics, and mechanisms.

Journal: Journal of chemical information and modeling 20120326

Title: Cytochrome P450 11A1 bioactivation of a kinase inhibitor in rats: use of radioprofiling, modulation of metabolism, and adrenocortical cell lines to evaluate adrenal toxicity.

Journal: Chemical research in toxicology 20120319

Title: Corticosteroid dependent and independent effects of a cannabinoid agonist on core temperature, motor activity, and prepulse inhibition of the acoustic startle reflex in Wistar rats.

Journal: Psychopharmacology 20120301

Title: Corticosterone synthesis inhibitor metyrapone ameliorates chronic hypobaric hypoxia induced memory impairment in rat.

Journal: Behavioural brain research 20120301

Title: Prolonged remission after long-term treatment with steroidogenesis inhibitors in Cushing's syndrome caused by ectopic ACTH secretion.

Journal: European journal of endocrinology 20120301

Title: Comparison of serum cortisol measurement by immunoassay and liquid chromatography-tandem mass spectrometry in patients receiving the 11β-hydroxylase inhibitor metyrapone.

Journal: Annals of clinical biochemistry 20120301

Title: A refined blood collection method for quantifying corticosterone.

Journal: Lab animal 20120301

Title: The effects of palm vitamin E on stress hormone levels and gastric lesions in stress-induced rats.

Journal: Archives of medical science : AMS 20120227

Title: Carney's complex: a successful pregnancy after bilateral adrenalectomy.

Journal: Archives of medical science : AMS 20120227

Title: Assessment of long-term efficacy and safety of metyrapone monotherapy in a patient with ACTH-independent macronodular adrenal hyperplasia.

Journal: Endocrine 20120201

Title: Permanent hypopituitarism is rare after structural traumatic brain injury in early childhood.

Journal: The Journal of clinical endocrinology and metabolism 20120201

Title: Pregnancy-induced Cushing's syndrome in recurrent pregnancies: case report and literature review.

Journal: The Australian & New Zealand journal of obstetrics & gynaecology 20120201

Title: Treatment of corticotroph deficiency.

Journal: Annales d'endocrinologie 20120201

Title: Modeling cortisol dynamics in the neuro-endocrine axis distinguishes normal, depression, and post-traumatic stress disorder (PTSD) in humans.

Journal: PLoS computational biology 20120201

Title: Advances in medical therapies for Cushing's syndrome.

Journal: Discovery medicine 20120201

Title: Interactions between cortisol and Rhesus glycoprotein expression in ureogenic toadfish, Opsanus beta.

Journal: The Journal of experimental biology 20120115

Title: Bupropion hydroxylation as a selective marker of rat CYP2B1 catalytic activity.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20120101

Title: Effects of cortisol on pregnancy rate and corpus luteum function in heifers: an in vivo study.

Journal: The Journal of reproduction and development 20120101

Title: Application of the new classification on patients with a disorder of sex development in indonesia.

Journal: International journal of endocrinology 20120101

Title: Stress hormones receptors in the amygdala mediate the effects of stress on the consolidation, but not the retrieval, of a non aversive spatial task.

Journal: PloS one 20120101

Title: Mechanisms of fetal programming in hypertension.

Journal: International journal of pediatrics 20120101

Title: Cortisol responses to mental stress and the progression of coronary artery calcification in healthy men and women.

Journal: PloS one 20120101

Title: Treatment Options in Cushing's Disease.

Journal: Clinical Medicine Insights. Oncology 20120101

Title: Successful long-term treatment of Cushing disease with mifepristone (RU486).

Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20120101

Title: Investigation of indazole unbinding pathways in CYP2E1 by molecular dynamics simulations.

Journal: PloS one 20120101

Title: Vascular aging and hemodynamic stability in the intraoperative period.

Journal: Frontiers in physiology 20120101

Title: Synaptic regulation of the hypothalamic-pituitary-adrenal axis and its modulation by glucocorticoids and stress.

Journal: Frontiers in cellular neuroscience 20120101

Title: Low dose adrenocorticotropic hormone test and adrenal insufficiency in critically ill acquired immunodeficiency syndrome patients.

Journal: Indian journal of endocrinology and metabolism 20120101

Title: Childhood adrenocortical carcinoma: Case report and review.

Journal: Indian journal of endocrinology and metabolism 20120101

Title: McCune-Albright syndrome and the extraskeletal manifestations of fibrous dysplasia.

Journal: Orphanet journal of rare diseases 20120101

Title: Stress and tinnitus-from bedside to bench and back.

Journal: Frontiers in systems neuroscience 20120101

Title: The combined dexamethasone/TSST paradigm--a new method for psychoneuroendocrinology.

Journal: PloS one 20120101

Title: Glucocorticoid-cholinergic interactions in the dorsal striatum in memory consolidation of inhibitory avoidance training.

Journal: Frontiers in behavioral neuroscience 20120101

Title: Management Strategies for Aggressive Cushing's Syndrome: From Macroadenomas to Ectopics.

Journal: Journal of oncology 20120101

Title: Biodegradation of bisphenol A and 4-alkylphenols by Novosphingobium sp. strain TYA-1 and its potential for treatment of polluted water.

Journal: Water science and technology : a journal of the International Association on Water Pollution Research 20120101

Title: Membrane mineralocorticoid but not glucocorticoid receptors of the dorsal hippocampus mediate the rapid effects of corticosterone on memory retrieval.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20111201

Title: Urine steroid metabolomics as a biomarker tool for detecting malignancy in adrenal tumors.

Journal: The Journal of clinical endocrinology and metabolism 20111201

Title: Adrenal disease in pregnancy.

Journal: Best practice & research. Clinical endocrinology & metabolism 20111201

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: NMDA receptors and fear extinction: implications for cognitive behavioral therapy.

Journal: Dialogues in clinical neuroscience 20111201

Title: Neurobiology of panic and pH chemosensation in the brain.

Journal: Dialogues in clinical neuroscience 20111201

Title: Stress-related noradrenergic activity prompts large-scale neural network reconfiguration.

Journal: Science (New York, N.Y.) 20111125

Title: Overnight ACTH-cortisol dose responsiveness: comparison with 24-h data, metyrapone administration and insulin-tolerance test in healthy adults.

Journal: Clinical endocrinology 20111101

Title: Biosynthesis of cholesterol and other sterols.

Journal: Chemical reviews 20111012

Title: Evidence for transcriptional regulation of the urea transporter in the gill of the Gulf toadfish, Opsanus beta.

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20111001

Title: Metyrapone and fluoxetine suppress enduring behavioral but not cardiac effects of subchronic stress in rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20111001

Title: Endocrine hypertension - Cushing's syndrome.

Journal: Indian journal of endocrinology and metabolism 20111001

Title: Cushing's surgery: Role of the anesthesiologist.

Journal: Indian journal of endocrinology and metabolism 20111001

Title: Successful outcome of pregnancy in a patient with Cushing's disease under treatment with ketoconazole during the first trimester of gestation.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20110901

Title: Isolation and characterization of RDX-degrading Rhodococcus species from a contaminated aquifer.

Journal: Biodegradation 20110901

Title: Mechanistic computational model of steroidogenesis in H295R cells: role of oxysterols and cell proliferation to improve predictability of biochemical response to endocrine active chemical--metyrapone.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110901

Title: Glucocorticoids are required for extinction of predator stress-induced hyperarousal.

Journal: Neurobiology of learning and memory 20110901

Title: Mitotane, metyrapone, and ketoconazole combination therapy as an alternative to rescue adrenalectomy for severe ACTH-dependent Cushing's syndrome.

Journal: The Journal of clinical endocrinology and metabolism 20110901

Title: Hypothalamic-pituitary-adrenal axis suppression in asthmatic children on inhaled and nasal corticosteroids: is the early-morning serum adrenocorticotropic hormone (ACTH) a useful screening test?

Journal: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20110901

Title: Comparison of serum cortisol measurement by immunoassay and liquid chromatography-tandem mass spectrometry in patients receiving the 11β-hydroxylase inhibitor metyrapone.

Journal: Annals of clinical biochemistry 20110901

Title: Effects of epinephrine and cortisol on the analgesic activity of metyrosine in rats.

Journal: Archives of pharmacal research 20110901

Title: Pituitary apoplexy.

Journal: Indian journal of endocrinology and metabolism 20110901

Title: Anesthesia and Intensive care implications for pituitary surgery: Recent trends and advancements.

Journal: Indian journal of endocrinology and metabolism 20110901

Title: 11β-hydroxysteroid dehydrogenases and the brain: from zero to hero, a decade of progress.

Journal: Frontiers in neuroendocrinology 20110801

Title: Hepatic cytochrome P450s attenuate the cytotoxicity induced by leflunomide and its active metabolite A77 1726 in primary cultured rat hepatocytes.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110801

Title: Metyrapone administration reduces the strength of an emotional memory trace in a long-lasting manner.

Journal: The Journal of clinical endocrinology and metabolism 20110801

Title: Type 2 diabetes identified in pregnancy secondary to Cushing's syndrome.

Journal: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20110801

Title: Metabolism of dl-praeruptorin A in rat liver microsomes using HPLC-electrospray ionization tandem mass spectrometry.

Journal: Archives of pharmacal research 20110801

Title: Brief neck restraint stress enhances long-term potentiation and suppresses long-term depression in the dentate gyrus of the mouse.

Journal: Brain research bulletin 20110715

Title: Low incidence of adrenal insufficiency after transsphenoidal surgery in patients with acromegaly: a long-term follow-up study.

Journal: The Journal of clinical endocrinology and metabolism 20110701

Title: Metyrapone restores the febrile response to Escherichia coli LPS in pregnant rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20110601

Title: Diagnosis of adrenal failure in critically ill patients.

Journal: Arquivos brasileiros de endocrinologia e metabologia 20110601

Title: The glucocorticoid system is required for the voluntary exercise-induced enhancement of learning and memory in rats.

Journal: Behavioural brain research 20110516

Title: Somatic and neuroendocrine responses to standard and biologically salient acoustic startle stimuli in monkeys.

Journal: Psychoneuroendocrinology 20110501

Title: Roles of cortisol and carbonic anhydrase in acid-base compensation in rainbow trout, Oncorhynchus mykiss.

Journal: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20110501

Title: Block of glucocorticoid synthesis during re-activation inhibits extinction of an established fear memory.

Journal: Neurobiology of learning and memory 20110501

Title: Management of pituitary tumors in pregnancy.

Journal: Nature reviews. Endocrinology 20110501

Title: Progesterone prevents corticosterone mediated inhibition of estrous behaviour in rats.

Journal: Indian journal of experimental biology 20110501

Title: Effects of endogenous glucocorticoid secretion on the interleukin-6 response to bacterial endotoxin in pregnant and non-pregnant rats.

Journal: The Journal of endocrinology 20110401

Title: Changes in HPA reactivity and noradrenergic functions regulate spatial memory impairments at delayed time intervals following cerebral ischemia.

Journal: Hormones and behavior 20110401

Title: Cortisol synthesis in epidermis is induced by IL-1 and tissue injury.

Journal: The Journal of biological chemistry 20110325

Title: Cisplatin-induced emesis: systematic review and meta-analysis of the ferret model and the effects of 5-HT₃ receptor antagonists.

Journal: Cancer chemotherapy and pharmacology 20110301

Title: Heat shock protein 70 is acute phase reactant: response elicited by tumor treatment with photodynamic therapy.

Journal: Cell stress & chaperones 20110301

Title: Development of individual differences in stress responsiveness: an overview of factors mediating the outcome of early life experiences.

Journal: Psychopharmacology 20110301

Title: A case of corticotroph carcinoma that caused multiple cranial nerve palsies, destructive petrosal bone invasion, and liver metastasis.

Journal: Endocrine pathology 20110301

Title: Culture of porcine hepatocytes or bile duct epithelial cells by inductive serum-free media.

Journal: In vitro cellular & developmental biology. Animal 20110301

Title: Hormone treatment of depression.

Journal: Dialogues in clinical neuroscience 20110301

Title: Single administration of metyrapone modifies sleep-wake patterns in the rat.

Journal: European journal of pharmacology 20110210

Title: Long-lasting cognitive deficit induced by stress is alleviated by acute administration of antidepressants.

Journal: Psychoneuroendocrinology 20110101

Title: Electrochemical investigations of cytochrome P450.

Journal: Biochimica et biophysica acta 20110101

Title: Evidence that prenatal programming of hypertension by dietary protein deprivation is mediated by fetal glucocorticoid exposure.

Journal: American journal of hypertension 20110101

Title: N-(Pyridin-3-yl)benzamides as selective inhibitors of human aldosterone synthase (CYP11B2).

Journal: Bioorganic & medicinal chemistry letters 20110101

Title: Lactobacillus rhamnosus HN001 attenuates allergy development in a pig model.

Journal: PloS one 20110101

Title: 11β-Hydroxylase inhibitors protect against seizures in mice by increasing endogenous neurosteroid synthesis.

Journal: Neuropharmacology 20110101

Title: Interaction between Diazepam and Hippocampal Corticosterone after Acute Stress: Impact on Memory in Middle-Aged Mice.

Journal: Frontiers in behavioral neuroscience 20110101

Title: Severe Hypoglycemia due to Isolated ACTH Deficiency in Children: A New Case Report and Review of the Literature.

Journal: International journal of pediatrics 20110101

Title: Clinical evaluation of non-surgical sterilization of male cats with single intra-testicular injection of calcium chloride.

Journal: BMC veterinary research 20110101

Title: Molecular dynamics analysis reveals structural insights into mechanism of nicotine N-demethylation catalyzed by tobacco cytochrome P450 mono-oxygenase.

Journal: PloS one 20110101

Title: Failure of functional imaging with gallium-68-DOTA-D-Phe1-Tyr3-octreotide positron emission tomography to localize the site of ectopic adrenocorticotropic hormone secretion: a case report.

Journal: Journal of medical case reports 20110101

Title: Decolorizing activity of malachite green and its mechanisms involved in dye biodegradation by Achromobacter xylosoxidans MG1.

Journal: Journal of molecular microbiology and biotechnology 20110101

Title: Hypothalamic-pituitary-adrenal axis suppression in asthmatic children on inhaled and nasal corticosteroids--more common than expected?

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20110101

Title: Alcohol-induced Cushing syndrome. Hypercortisolism caused by alcohol abuse.

Journal: The Netherlands journal of medicine 20110101

Title: Prader-Willi syndrome: A primer for clinicians.

Journal: International journal of pediatric endocrinology 20110101

Title: Regulation of excitatory synapses and fearful memories by stress hormones.

Journal: Frontiers in behavioral neuroscience 20110101

Title: Etomidate and mortality in cirrhotic patients with septic shock.

Journal: BMC clinical pharmacology 20110101

Title: Metyrapone: a management option for ectopic ACTH syndrome in small cell lung cancer treated with intravenous etoposide.

Journal: BMJ case reports 20110101

Title: Evidence that metyrapone in the presence of inflammation modulates cytokine mRNA expression.

Journal: Cytokine 20101201

Title: Pineal-adrenal-immune system relationship under thermal stress: effect on physiological, endocrine, and non-specific immune response in goats.

Journal: Journal of physiology and biochemistry 20101201

Title: Thymus-derived glucocorticoids mediate androgen effects on thymocyte homeostasis.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20101201

Title: Normal cortisol response on low-dose synacthen (1 microg) test in children with Prader Willi syndrome.

Journal: The Journal of clinical endocrinology and metabolism 20101201

Title: Decreased prereceptorial glucocorticoid activating capacity in starvation due to an oxidative shift of pyridine nucleotides in the endoplasmic reticulum.

Journal: FEBS letters 20101119

Title: Blocking corticotropin-releasing factor-2 receptors, but not corticotropin-releasing factor-1 receptors or glucocorticoid feedback, disrupts the development of conditioned defeat.

Journal: Physiology & behavior 20101102

Title: A randomised controlled study of risperidone and olanzapine for schizophrenic patients with neuroleptic-induced acute dystonia or parkinsonism.

Journal: Journal of psychopharmacology (Oxford, England) 20101101

Title: How right is the righting reflex? The risk of false positives in neuroprotection studies using behavioral measures to certify forebrain ischemia.

Journal: Neurological research 20101101

Title: Effects on plasma corticosterone levels and brain serotonin from interference with methamphetamine-induced corticosterone release in neonatal rats.

Journal: Stress (Amsterdam, Netherlands) 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Accelerated trace eyeblink conditioning after cortisol IV-infusion.

Journal: Neurobiology of learning and memory 20101101

Title: Cloning and heterologous expression of P450Um-1, a novel bacterial P450 gene, for hydroxylation of immunosuppressive agent AS1387392.

Journal: The Journal of antibiotics 20101101

Title: Cortisol measurement in patients receiving metyrapone therapy.

Journal: Annals of clinical biochemistry 20101101

Title: Influence of adrenal hormones in the occurrence and prevention of stress ulcers.

Journal: Journal of pediatric surgery 20101101

Title: Measurement of cortisol, cortisone, prednisolone, dexamethasone and 11-deoxycortisol with ultra high performance liquid chromatography-tandem mass spectrometry: Application for plasma, plasma ultrafiltrate, urine and saliva in a routine laboratory.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101015

Title: Metyrapone blunts stress-induced hyperthermia and increased locomotor activity independently of glucocorticoids and neurosteroids.

Journal: Psychoneuroendocrinology 20101001

Title: Chronic stress enhances the corticosterone response and neurotoxicity to +3,4-methylenedioxymethamphetamine (MDMA): the role of ambient temperature.

Journal: The Journal of pharmacology and experimental therapeutics 20101001

Title: Physiology and biochemistry of reduction of azo compounds by Shewanella strains relevant to electron transport chain.

Journal: Applied microbiology and biotechnology 20101001

Title: Effects of corticosterone synthesis inhibitor metyrapone on anxiety-related behaviors in Lurcher mutant mice.

Journal: Physiology & behavior 20100901

Title: Replacement of imidazolyl by pyridyl in biphenylmethylenes results in selective CYP17 and dual CYP17/CYP11B1 inhibitors for the treatment of prostate cancer.

Journal: Journal of medicinal chemistry 20100812

Title: Cortisol is involved in temperature-dependent sex determination in the Japanese flounder.

Journal: Endocrinology 20100801

Title: High temperature causes masculinization of genetically female medaka by elevation of cortisol.

Journal: Molecular reproduction and development 20100801

Title: Atypical thymic carcinoid associated with Cushing's syndrome.

Journal: The Tokai journal of experimental and clinical medicine 20100720

Title: Anti-inflammatory effect of bee venom on antigen-induced arthritis in rabbits: influence of endogenous glucocorticoids.

Journal: Journal of ethnopharmacology 20100706

Title: Pharmacodynamic and pharmacokinetic characterization of the aldosterone synthase inhibitor FAD286 in two rodent models of hyperaldosteronism: comparison with the 11beta-hydroxylase inhibitor metyrapone.

Journal: The Journal of pharmacology and experimental therapeutics 20100701

Title: Feedback inhibition of human scavenger receptor class B type I gene expression by glucocorticoid in adrenal and ovarian cells.

Journal: Endocrinology 20100701

Title: Defining age limits of the sensitive period for attachment learning in rat pups.

Journal: Developmental psychobiology 20100701

Title: [Pituitary adenomas--where is the treatment heading at the beginning of the 21st century?].

Journal: Vnitrni lekarstvi 20100701

Title: Origin of ultradian pulsatility in the hypothalamic-pituitary-adrenal axis.

Journal: Proceedings. Biological sciences 20100607

Title: Role of metabolic activation and the TRPA1 receptor in the sensory irritation response to styrene and naphthalene.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100601

Title: [Contribution of glucocorticoid hormones to gastroprotective effect of ischemic preconditioning in rats with normal and deficient prostaglandin production].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20100601

Title: The PXR is a drug target for chronic inflammatory liver disease.

Journal: The Journal of steroid biochemistry and molecular biology 20100531

Title: Corticosterone synthesis inhibitor-induced decrease in the age-dependant expression of nitric oxide synthase 3 in the preterm ductus arteriosus of rats.

Journal: The Journal of veterinary medical science 20100501

Title: CRF-1 antagonist and CRF-2 agonist decrease binge-like ethanol drinking in C57BL/6J mice independent of the HPA axis.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100501

Title: From then to now: lessons from developments in our understanding of the pituitary gland.

Journal: The Ulster medical journal 20100501

Title: Stress and IL-1beta contribute to the development of depressive-like behavior following peripheral nerve injury.

Journal: Molecular psychiatry 20100401

Title: Regulation of MCP-1 production in brain by stress and noradrenaline-modulating drugs.

Journal: Journal of neurochemistry 20100401

Title: Suppressing the morning rise in cortisol impairs free recall.

Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20100401

Title: Role of corticosterone in trace and delay conditioned fear-potentiated startle in rats.

Journal: Behavioral neuroscience 20100401

Title: Increased stress-induced intra-hippocampus corticosterone rise associated with memory impairments in middle-aged mice.

Journal: Neurobiology of learning and memory 20100301

Title: Stress at learning facilitates memory formation by regulating AMPA receptor trafficking through a glucocorticoid action.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100201

Title: Computational model of steroidogenesis in human H295R cells to predict biochemical response to endocrine-active chemicals: model development for metyrapone.

Journal: Environmental health perspectives 20100201

Title: Rapid stress-induced corticosterone rise in the hippocampus reverses serial memory retrieval pattern.

Journal: Hippocampus 20100101

Title: Biotransformation of beta-myrcene to geraniol by a strain of Rhodococcus erythropolis isolated by selective enrichment from hop plants.

Journal: Applied microbiology and biotechnology 20100101

Title: Altered redox state of luminal pyridine nucleotides facilitates the sensitivity towards oxidative injury and leads to endoplasmic reticulum stress dependent autophagy in HepG2 cells.

Journal: The international journal of biochemistry & cell biology 20100101

Title: Biochemical predictors of outcome of pituitary surgery for Cushing's disease.

Journal: Neuroendocrinology 20100101

Title: Stress and aversive learning in a wild vertebrate: the role of corticosterone in mediating escape from a novel stressor.

Journal: The American naturalist 20100101

Title: On the diagnosis and investigation of adrenal insufficiency in adults.

Journal: Annals of clinical biochemistry 20100101

Title: Pitfalls in the diagnosis of central adrenal insufficiency in children.

Journal: Endocrine development 20100101

Title: Endothelial dysfunction aassociated with hypercortisolism is reversible in Cushing's syndrome.

Journal: Endocrine journal 20100101

Title: A case of ectopic adrenocorticotropic hormone-producing pancreatic neuroendocrine tumor with multiple liver metastases.

Journal: Endocrine journal 20100101

Title: Unusual cause of ectopic secretion of adrenocorticotropic hormone: Cushing syndrome attributable to small cell prostate cancer.

Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20100101

Title: Unchanged triclabendazole kinetics after co-administration with ivermectin and methimazole: failure of its therapeutic activity against triclabendazole-resistant liver flukes.

Journal: BMC veterinary research 20100101

Title: Glucocorticoid effects on the programming of AT1b angiotensin receptor gene methylation and expression in the rat.

Journal: PloS one 20100101

Title: Corticosteroids: way upstream.

Journal: Molecular brain 20100101

Title: Chicken blood provides a suitable meal for the sand fly Lutzomyia longipalpis and does not inhibit Leishmania development in the gut.

Journal: Parasites & vectors 20100101

Title: An ACTH-secreting pituitary adenoma within the sphenoid sinus.

Journal: Internal medicine (Tokyo, Japan) 20100101

Title: Diagnostic predicament of secondary adrenal insufficiency.

Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20100101

Title: Effects of Melatonin on Adrenal Cortical Functions of Indian Goats under Thermal Stress.

Journal: Veterinary medicine international 20100101

Title: Prolactinomas, Cushing's disease and acromegaly: debating the role of medical therapy for secretory pituitary adenomas.

Journal: BMC endocrine disorders 20100101

Title: Explaining the atypical reaction profiles of heme enzymes with a novel mechanistic hypothesis and kinetic treatment.

Journal: PloS one 20100101

Title: Medical therapy of Cushing's disease: where are we now?

Journal: Frontiers of hormone research 20100101

Title: Modulation of Sleep Homeostasis by Corticotropin Releasing Hormone in REM Sleep-Deprived Rats.

Journal: International journal of endocrinology 20100101

Title: Impact of sleep and its disturbances on hypothalamo-pituitary-adrenal axis activity.

Journal: International journal of endocrinology 20100101

Title: Ectopic corticotropin-releasing hormone (CRH) syndrome from metastatic small cell carcinoma: a case report and review of the literature.

Journal: Diagnostic pathology 20100101

Title: Acute adrenal crisis in an asthmatic child treated with inhaled fluticasone proprionate.

Journal: International journal of pediatric endocrinology 20100101

Title: Neuropsychiatric disorders in Cushing's syndrome.

Journal: Neuroendocrinology 20100101

Title: Management of diabetes mellitus in Cushing's syndrome.

Journal: Neuroendocrinology 20100101

Title: Medical treatment of Cushing's syndrome: adrenal-blocking drugs and ketaconazole.

Journal: Neuroendocrinology 20100101

Title: Does early mismatched nutrition predispose to hypertension and atherosclerosis, in male mice?

Journal: PloS one 20100101

Title: Treatment of Cushing disease: overview and recent findings.

Journal: Therapeutics and clinical risk management 20100101

Title: Clinical features and management of ectopic ACTH syndrome at a single institute in Japan.

Journal: Endocrine journal 20100101

Title: Molecular evolution and functional divergence of the cytochrome P450 3 (CYP3) Family in Actinopterygii (ray-finned fish).

Journal: PloS one 20100101

Title: Metabolic activity and mRNA levels of human cardiac CYP450s involved in drug metabolism.

Journal: PloS one 20100101

Title: Novel medical treatment of pituitary adrenocorticotropic hormone-dependent hypercortisolism: a case study.

Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20100101

Title: Effect of metyrapone on the fluoxetine-induced change in extracellular dopamine, serotonin and their metabolites in the rat frontal cortex.

Journal: Pharmacological reports : PR 20100101

Title: Cosyntropin as a diagnostic agent in the screening of patients for adrenocortical insufficiency.

Journal: Clinical pharmacology : advances and applications 20100101

Title: Chewing under restraint stress inhibits the stress-induced suppression of cell birth in the dentate gyrus of aged SAMP8 mice.

Journal: Neuroscience letters 20091211

Title: Influence of metyrapone treatment during pregnancy on the development and maturation of brain monoaminergic systems in the rat.

Journal: Acta physiologica (Oxford, England) 20091201

Title: Drugs in the medical treatment of Cushing's syndrome.

Journal: Expert opinion on emerging drugs 20091201

Title: Effects of endogenous glucocorticoids on allergic inflammation and T(H)1 /T(H)2 balance in airway allergic disease.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20091201

Title: Rationale for treatment and therapeutic options in Cushing's disease.

Journal: Best practice & research. Clinical endocrinology & metabolism 20091201

Title: Ischemic preconditioning attenuates gastric ischemia-reperfusion injury through involvement of glucocorticoids.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20091201

Title: Isolation of Streptomyces sp. strain capable of butyltin compounds degradation with high efficiency.

Journal: Journal of hazardous materials 20091115

Title: Differential response of Leydig cells in expressing 11beta-HSD type I and cytochrome P450 aromatase in male rats subjected to corticosterone deficiency.

Journal: Molecular and cellular endocrinology 20091113

Title: Hypothalamic-pituitary-adrenal axis abnormalities in response to deletion of 11beta-HSD1 is strain-dependent.

Journal: Journal of neuroendocrinology 20091101

Title: Transfer of metyrapone and its metabolite, rac-metyrapol, into breast milk.

Journal: Journal of human lactation : official journal of International Lactation Consultant Association 20091101

Title: Profound neutropenia resulting from metyrapone-induced adrenal crisis.

Journal: American journal of hematology 20091101

Title: [Participation of glucocorticoid hormones in gastroprotection during ischemia and ischemia-reperfusion in rats].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20091101

Title: Glucocorticoid receptor and mitogen-activated protein kinase activity after restraint stress and acoustic trauma.

Journal: Journal of neurotrauma 20091001

Title: Pituitary response to metyrapone in Gulf War veterans: relationship to deployment, PTSD and unexplained health symptoms.

Journal: Psychoneuroendocrinology 20091001

Title: Gene expression changes in the hypothalamus provide evidence for regionally-selective changes in IL-1 and microglial markers after acute stress.

Journal: Brain, behavior, and immunity 20091001

Title: Feeding pregnant rats a low-protein diet alters the hepatic expression of SREBP-1c in their offspring via a glucocorticoid-related mechanism.

Journal: Endocrine 20091001

Title: Theoretical characterization of substrate access/exit channels in the human cytochrome P450 3A4 enzyme: involvement of phenylalanine residues in the gating mechanism.

Journal: The journal of physical chemistry. B 20091001

Title: Management of endocrine manifestations and the use of mitotane as a chemotherapeutic agent for adrenocortical carcinoma.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090920

Title: Use of morning serum cortisol level after transsphenoidal resection of pituitary adenoma to predict the need for long-term glucocorticoid supplementation.

Journal: Journal of neurosurgery 20090901

Title: An approach to the management of patients with residual Cushing's disease.

Journal: Journal of neuro-oncology 20090901

Title: Thymocyte-synthesized glucocorticoids play a role in thymocyte homeostasis and are down-regulated by adrenocorticotropic hormone.

Journal: Endocrinology 20090901

Title: Cross reactions elicited by serum 17-OH progesterone and 11-desoxycortisol in cortisol assays.

Journal: Clinica chimica acta; international journal of clinical chemistry 20090901

Title: Ectopic Cushing's syndrome due to a pheochromocytoma: a new case in the post-partum and review of literature.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20090901

Title: Exercise-related hypoglycemia-associated autonomic failure in diabetes.

Journal: Diabetes 20090901

Title: Diagnosis of diseases of steroid hormone production, metabolism and action.

Journal: Journal of clinical research in pediatric endocrinology 20090901

Title: Characterization of the angiotensin (AT1b) receptor promoter and its regulation by glucocorticoids.

Journal: Journal of molecular endocrinology 20090801

Title: Structure-activity relationship of etomidate derivatives at the GABA(A) receptor: Comparison with binding to 11beta-hydroxylase.

Journal: Bioorganic & medicinal chemistry letters 20090801

Title: A prospective study on the incidence and predictive factors of relative adrenal insufficiency in Korean critically-ill patients.

Journal: Journal of Korean medical science 20090801

Title: The relationship between central adrenal insufficiency and sleep-related breathing disorders in children with Prader-Willi syndrome.

Journal: The Journal of clinical endocrinology and metabolism 20090701

Title: Thyroid hormone activation in vascular smooth muscle cells is negatively regulated by glucocorticoid.

Journal: Thyroid : official journal of the American Thyroid Association 20090701

Title: Hypothalamic-pituitary-adrenocortical system dysregulation and new treatment strategies in depression.

Journal: Expert review of neurotherapeutics 20090701

Title: Metyrapone decreases locomotion acutely.

Journal: Neuroscience letters 20090619

Title: The regulatory role of glucocorticoid and mineralocorticoid receptors in pulsatile urea excretion of the gulf toadfish, Opsanus beta.

Journal: The Journal of experimental biology 20090601

Title: Modeling kinetics of subcellular disposition of chemicals.

Journal: Chemical reviews 20090513

Title: A novel use of etomidate for intentional adrenal suppression to control severe hypercortisolemia in childhood.

Journal: Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20090501

Title: [Cushing's syndrome: special issues].

Journal: Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20090501

Title: Chronic unpredictable stress augments +3,4-methylenedioxymethamphetamine-induced monoamine depletions: the role of corticosterone.

Journal: Neuroscience 20090410

Title: Corticosterone- or metapyrone-induced alterations in adrenal function and expression of the arginine vasotocin receptor VT2 in the pituitary gland of domestic fowl, Gallus gallus.

Journal: General and comparative endocrinology 20090401

Title: Flexible structure of cytochrome P450: promiscuity of ligand binding in the CYP3A4 heme pocket.

Journal: Anticancer research 20090301

Title: Ketoconazole treatment for Cushing syndrome in McCune-Albright syndrome.

Journal: The Journal of pediatrics 20090301

Title: Priming of rotational behavior by a dopamine receptor agonist in Hemiparkinsonian rats: movement-dependent induction.

Journal: Neuroscience 20090218

Title: A steered molecular dynamics method with adaptive direction adjustments.

Journal: Biochemical and biophysical research communications 20090206

Title: Endogenous cortisol suppression with metyrapone enhances acoustic startle in healthy subjects.

Journal: Hormones and behavior 20090201

Title: Tissue-specific difference in the molecular mechanisms for the development of acute insulin resistance after injury.

Journal: Endocrinology 20090101

Title: Glucocorticoid inhibition in the treatment of depression: can we think outside the endocrine hypothalamus?

Journal: Depression and anxiety 20090101

Title: Energy generation coupled to azoreduction by membranous vesicles from Shewanella decolorationis S12.

Journal: Journal of microbiology and biotechnology 20090101

Title: The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism.

Journal: Nuclear receptor signaling 20090101

Title: Low affinity glucocorticoid binding site ligands as potential anti-fibrogenics.

Journal: Comparative hepatology 20090101

Title: Prenatal stress, glucocorticoids and the programming of adult disease.

Journal: Frontiers in behavioral neuroscience 20090101

Title: Early life stress as an influence on limbic epilepsy: an hypothesis whose time has come?

Journal: Frontiers in behavioral neuroscience 20090101

Title: Structural basis for substrate specificity in human monomeric carbonyl reductases.

Journal: PloS one 20090101

Title: Adrenocortical responsiveness to infusions of physiological doses of ACTH is not altered in posttraumatic stress disorder.

Journal: Frontiers in behavioral neuroscience 20090101

Title: Tuning microbial hosts for membrane protein production.

Journal: Microbial cell factories 20090101

Title: Vulnerability to stroke: implications of perinatal programming of the hypothalamic-pituitary-adrenal axis.

Journal: Frontiers in behavioral neuroscience 20090101

Title: Potentiation of the antidepressant-like effect of desipramine or reboxetine by metyrapone in the forced swimming test in rats.

Journal: Pharmacological reports : PR 20090101

Title: Medical treatment of Cushing's disease: Overview and recent findings.

Journal: International journal of general medicine 20090101

Title: How do azoles inhibit cytochrome P450 enzymes? A density functional study.

Journal: The journal of physical chemistry. A 20081218

Title: A patient with ectopic cortisol production derived from malignant testicular masses.

Journal: Nature clinical practice. Endocrinology & metabolism 20081201

Title: Contribution of glucocorticoids to protective influence of preconditioning mild stress against stress-induced gastric erosions.

Journal: Annals of the New York Academy of Sciences 20081201

Title: Characterization of CYP2A13*2, a variant cytochrome P450 allele previously found to be associated with decreased incidences of lung adenocarcinoma in smokers.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20081101

Title: Effects of the combination of metyrapone and oxazepam on cocaine and food self-administration in rats.

Journal: Pharmacology, biochemistry, and behavior 20081101

Title: Corticotropin tests for hypothalamic-pituitary- adrenal insufficiency: a metaanalysis.

Journal: The Journal of clinical endocrinology and metabolism 20081101

Title: Hypocortisolemic clamp unmasks jointly feedforward- and feedback-dependent control of overnight ACTH secretion.

Journal: European journal of endocrinology 20081101

Title: Fatal pneumocystis jirovecii pneumonia in a case of ectopic Cushing's syndrome due to neuroendocrine carcinoma of the kidney.

Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20081001

Title: A simple and cost-effective approach to assessment of pituitary adrenocorticotropin and growth hormone reserve: combined use of the overnight metyrapone test and insulin-like growth factor-I standard deviation scores.

Journal: The Journal of clinical endocrinology and metabolism 20081001

Title: Local and systemic glucocorticoid metabolism in inflammatory arthritis.

Journal: Annals of the rheumatic diseases 20080901

Title: Bringing light to the dark side of insulin: a journey across the blood-brain barrier.

Journal: Diabetes 20080901

Title: Mechanism of sulfite cytotoxicity in isolated rat hepatocytes.

Journal: Chemico-biological interactions 20080811

Title: Effects of corticosterone deficiency and its replacement on Leydig cell steroidogenesis.

Journal: Journal of cellular biochemistry 20080801

Title: Inhibition of cortisol production by metyrapone enhances trace, but not delay, eyeblink conditioning.

Journal: Psychopharmacology 20080801

Title: Metyrapone prevents cortisone-induced preadipocyte differentiation by depleting luminal NADPH of the endoplasmic reticulum.

Journal: Biochemical pharmacology 20080801

Title: Testing for hypothalamic-pituitary-adrenal axis suppression in asthmatic children.

Journal: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20080801

Title: The pilocarpine model of temporal lobe epilepsy.

Journal: Journal of neuroscience methods 20080730

Title: Method for comparing the structures of protein ligand-binding sites and application for predicting protein-drug interactions.

Journal: Proteins 20080701

Title: Treatment of adrenocorticotropin-dependent Cushing's syndrome: a consensus statement.

Journal: The Journal of clinical endocrinology and metabolism 20080701

Title: Glucocorticoids enhance taste aversion memory via actions in the insular cortex and basolateral amygdala.

Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20080701

Title: Distribution and corticosteroid regulation of glucocorticoid receptor in the brain of Xenopus laevis.

Journal: The Journal of comparative neurology 20080620

Title: Effect of organic and inorganic nitrogenous compounds on RDX degradation and cytochrome P-450 expression in Rhodococcus strain YH1.

Journal: Biodegradation 20080601

Title: Hypothalamus-pituitary-adrenal axis evaluation in patients with hypothalamo-pituitary disorders: comparison of different provocative tests.

Journal: Clinical endocrinology 20080601

Title: Pharmacological treatment of hypercortisolism.

Journal: Current opinion in endocrinology, diabetes, and obesity 20080601

Title: Prolonged remission of severe Cushing syndrome without adrenalectomy in an infant with McCune-Albright syndrome.

Journal: The Journal of pediatrics 20080601

Title: Cocaine decreases the expression of PSA-NCAM protein and attenuates long-term potentiation via glucocorticoid receptors in the rat dentate gyrus.

Journal: The European journal of neuroscience 20080601

Title: Stress impairs reconsolidation of drug memory via glucocorticoid receptors in the basolateral amygdala.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080521

Title: Evolutionarily conserved glucocorticoid regulation of corticotropin-releasing factor expression.

Journal: Endocrinology 20080501

Title: Chronic stress enhances methamphetamine-induced extracellular glutamate and excitotoxicity in the rat striatum.

Journal: Synapse (New York, N.Y.) 20080501

Title: High prevalence of central adrenal insufficiency in patients with Prader-Willi syndrome.

Journal: The Journal of clinical endocrinology and metabolism 20080501

Title: Malocclusion induces chronic stress.

Journal: Okajimas folia anatomica Japonica 20080501

Title: New selective inhibitors of steroid 11beta-hydroxylation in the adrenal cortex. Synthesis and structure-activity relationship of potent etomidate analogues.

Journal: Journal of medicinal chemistry 20080410

Title: Metyrapone and mifepristone reverse recognition memory loss induced by spontaneous morphine withdrawal in mice.

Journal: Basic & clinical pharmacology & toxicology 20080401

Title: Preoperative management of Cushing's syndrome with metyrapone for severe psychiatric disturbances.

Journal: International journal of urology : official journal of the Japanese Urological Association 20080401

Title: Glucocorticoids are not responsible for paradoxical sleep deprivation-induced memory impairments.

Journal: Sleep 20080401

Title: Differential effect of corticosterone deficiency on the expression of LH, prolactin and insulin receptors on rat Leydig cells.

Journal: Molecular and cellular endocrinology 20080326

Title: Hypophyseal corticosteroids stimulate somatotrope differentiation in the embryonic chicken pituitary gland.

Journal: Histochemistry and cell biology 20080301

Title: High-affinity binding of [3H]cimetidine to a heme-containing protein in rat brain.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080301

Title: Assessment of in vitro effects of metyrapone on Leydig cell steroidogenesis.

Journal: Steroids 20080301

Title: Biotransformation of flubendazole and selected model xenobiotics in Haemonchus contortus.

Journal: Veterinary parasitology 20080214

Title: Antiglucocorticoid treatments for mood disorders.

Journal: The Cochrane database of systematic reviews 20080123

Title: Mood and neuroendocrine response to a chemical stressor, metyrapone, in buprenorphine-maintained heroin dependence.

Journal: Biological psychiatry 20080115

Title: One single dose of etomidate negatively influences adrenocortical performance for at least 24h in children with meningococcal sepsis.

Journal: Intensive care medicine 20080101

Title: Memory consolidation during sleep: interactive effects of sleep stages and HPA regulation.

Journal: Stress (Amsterdam, Netherlands) 20080101

Title: [Medical treatment for Cushing's syndrome].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20080101

Title: Effect of a 14-day course of systemic corticosteroids on the hypothalamic-pituitary-adrenal-axis in patients with acute exacerbation of chronic obstructive pulmonary disease.

Journal: BMC pulmonary medicine 20080101

Title: Reduction in salivary cortisol concentration correlates with resolution of psychosis in Cushing's syndrome.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20080101

Title: Acromegaly.

Journal: Orphanet journal of rare diseases 20080101

Title: Timing-dependent effects of restraint stress on eosinophilic airway inflammation in mice.

Journal: Neuroimmunomodulation 20080101

Title: Biology and therapy of fibromyalgia. Evidence-based biomarkers for fibromyalgia syndrome.

Journal: Arthritis research & therapy 20080101

Title: Steroid biosynthesis inhibitors in the therapy of hypercortisolism: theory and practice.

Journal: Current medicinal chemistry 20080101

Title: Effects of co-administration of fluoxetine or tianeptine with metyrapone on immobility time and plasma corticosterone concentration in rats subjected to the forced swim test.

Journal: Pharmacological reports : PR 20080101

Title: Hirsutism: clinico-investigative profile of 50 Indian patients.

Journal: Indian journal of dermatology 20080101

Title: Effect of norharmane in vitro on juvenile hormone epoxide hydrolase activity in the lower termite, Reticulitermes speratus.

Journal: Journal of insect science (Online) 20080101

Title: Neurosteroid allopregnanolone mediates anxiolytic effect of etifoxine in rats.

Journal: Brain research 20071212

Title: Opioids, dopamine, stress, and the addictions.

Journal: Dialogues in clinical neuroscience 20071201

Title: Comparative CYP-dependent binding of the adrenocortical toxicants 3-methylsulfonyl-DDE and o,p'-DDD in Y-1 adrenal cells.

Journal: Archives of toxicology 20071101

Title: Cocaine- and amphetamine-regulated transcript (CART) peptide as an in vivo regulator of cardiac function in Rana ridibunda frog.

Journal: Experimental physiology 20071101

Title: Role of maternal corticosterone in the development and maturation of the aminoacidergic systems of the rat brain.

Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20071101

Title: Pharmacological management of Cushing's syndrome: an update.

Journal: Arquivos brasileiros de endocrinologia e metabologia 20071101

Title: Temporospatial patterns of COX-2 expression and pyramidal cell degeneration in the rat hippocampus after trimethyltin administration.

Journal: Neuroscience research 20071001

Title: Hypothalamic-pituitary-adrenal axis suppression in asthmatic children on inhaled corticosteroids (Part 2)--the risk as determined by gold standard adrenal function tests: a systematic review.

Journal: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20070901

Title: An update on the diagnosis of adrenal insufficiency and the use of corticotherapy in critical illness.

Journal: The Annals of pharmacotherapy 20070901

Title: Acute effects of glucocorticoids on endothelial fibrinolytic and vasodilator function in humans.

Journal: Journal of cardiovascular pharmacology 20070901

Title: Effect of glucocorticoid depletion on heat-induced Hsp70, IL-1beta and TNF-alpha gene expression.

Journal: Brain research 20070820

Title: Activities of biotransformation enzymes in pheasant (Phasianus colchicus) and their modulation by in vivo administration of mebendazole and flubendazole.

Journal: Research in veterinary science 20070801

Title: Neurotoxic effects of chronic restraint stress in the striatum of methamphetamine-exposed rats.

Journal: Psychopharmacology 20070801

Title: Increases in plasma corticosterone and stretched-attend postures in rats naive and previously exposed to the elevated plus-maze are sensitive to the anxiolytic-like effects of midazolam.

Journal: Hormones and behavior 20070801

Title: Hypothalamic-pituitary-adrenal axis suppression in asthmatic children on inhaled corticosteroids: part 1. Which test should be used?

Journal: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20070801

Title: Construction of 3D models of the CYP11B family as a tool to predict ligand binding characteristics.

Journal: Journal of computer-aided molecular design 20070801

Title: Repeat doses of antenatal steroids and hypothalamic-pituitary-adrenal axis (HPA) function.

Journal: American journal of obstetrics and gynecology 20070701

Title: Modulation of hepatic and renal metabolism and toxicity of trichloroethylene and perchloroethylene by alterations in status of cytochrome P450 and glutathione.

Journal: Toxicology 20070603

Title: Preclinical Cushing's disease characterized by massive adrenal hyperplasia and hormonal changes after three years of metyrapone therapy.

Journal: Endocrine journal 20070601

Title: Sex differences in ACTH pulsatility following metyrapone blockade in patients with major depression.

Journal: Psychoneuroendocrinology 20070601

Title: Biotransformation of polymethoxylated flavonoids: access to their 4'-O-demethylated metabolites.

Journal: Journal of natural products 20070601

Title: Basal serum cortisol levels are not predictive of response to corticotropin but have prognostic significance in patients with septic shock.

Journal: Journal of Korean medical science 20070601

Title: Neuropsychiatric manifestations of depression in multiple sclerosis: neuroinflammatory, neuroendocrine, and neurotrophic mechanisms in the pathogenesis of immune-mediated depression.

Journal: Dialogues in clinical neuroscience 20070601

Title: Glutamate NMDA receptors within the amygdala participate in the modulatory effect of glucocorticoids on extinction of conditioned fear in rats.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070501

Title: Effects of peroxisome proliferator-activated receptor-alpha and -gamma agonists on 11beta-hydroxysteroid dehydrogenase type 1 in subcutaneous adipose tissue in men.

Journal: The Journal of clinical endocrinology and metabolism 20070501

Title: Indirect role of alpha2-adrenoreceptors in anti-ulcer effect mechanism of nimesulide in rats.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20070501

Title: Matching salt intake to physiological need in rats using foraging protocols.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20070501

Title: Effects of metyrapone on hypothalamic-pituitary-adrenal axis and sleep in women with post-traumatic stress disorder.

Journal: Biological psychiatry 20070415

Title: Fe(III)-enhanced Azo Reduction by Shewanella decolorationis S12.

Journal: Applied microbiology and biotechnology 20070401

Title: Possible pathway(s) of metyrapone egress from the active site of cytochrome P450 3A4: a molecular dynamics simulation.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070401

Title: [Perioperative treatment of a patient with ectopic ACTH-producing pheochromocytoma].

Journal: Masui. The Japanese journal of anesthesiology 20070401

Title: Effects of electron donors and acceptors on anaerobic reduction of azo dyes by Shewanella decolorationis S12.

Journal: Applied microbiology and biotechnology 20070201

Title: A noninflammatory interleukin-1beta fragment stimulates fetal lung fluid absorption in guinea pigs.

Journal: The Journal of pharmacology and experimental therapeutics 20070201

Title: Etomidate use for Cushing's syndrome caused by an ectopic adrenocorticotropic hormone-producing tumor.

Journal: The Annals of pharmacotherapy 20070201

Title: In silico prediction of pregnane X receptor activators by machine learning approaches.

Journal: Molecular pharmacology 20070101

Title: Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers.

Journal: The Journal of pharmacology and experimental therapeutics 20070101

Title: Sound conditioning protects hearing by activating the hypothalamic-pituitary-adrenal axis.

Journal: Neurobiology of disease 20070101

Title: Steroid-dependent ACTH-produced thymic carcinoid: regulation of POMC gene expression by cortisol via methylation of its promoter region.

Journal: Hormone research 20070101

Title: Vitamin C. Biosynthesis, recycling and degradation in mammals.

Journal: The FEBS journal 20070101

Title: Adrenal participation in thymocyte death by anti-CD3 antibodies in vivo.

Journal: Microbiology and immunology 20070101

Title: Stimulation of MAP kinase pathways after maternal IL-1beta exposure induces fetal lung fluid absorption in guinea pigs.

Journal: Respiratory research 20070101

Title: [Characteristics of uptake, transport and efflux of Z- and E-ajoenes in Caco-2 cell monolayers in vitro].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20070101

Title: Simultaneous ectopic adrenocorticotropic hormone syndrome and adrenal metastasis of a medullary thyroid carcinoma causing paraneoplastic Cushing's syndrome.

Journal: International seminars in surgical oncology : ISSO 20070101

Title: The acute effects of a mineralocorticoid receptor (MR) agonist on nocturnal hypothalamic-adrenal-pituitary (HPA) axis activity in healthy controls.

Journal: Psychoneuroendocrinology 20070101

Title: Differential MR/GR activation in mice results in emotional states beneficial or impairing for cognition.

Journal: Neural plasticity 20070101

Title: [Quo vadis, hypophysis? Some news and prospects].

Journal: Vnitrni lekarstvi 20070101

Title: Lack of cortisol response in patients with posttraumatic stress disorder (PTSD) undergoing a diagnostic interview.

Journal: BMC psychiatry 20070101

Title: Medical management of Cushing disease.

Journal: Neurosurgical focus 20070101

Title: A possible role for the endocannabinoid system in the neurobiology of depression.

Journal: Clinical practice and epidemiology in mental health : CP & EMH 20070101

Title: Effect of repeated co-treatment with imipramine and metyrapone on the behavioral reactivity of the central serotonin, dopamine and alpha 1-adrenergic systems in rats.

Journal: Pharmacological reports : PR 20070101

Title: Stress and memory: behavioral effects and neurobiological mechanisms.

Journal: Neural plasticity 20070101

Title: Sex differences in the ACTH response to 24H metyrapone in depression.

Journal: Brain research 20061218

Title: Diagnosis of adrenal insufficiency in severe sepsis and septic shock.

Journal: American journal of respiratory and critical care medicine 20061215

Title: [Anaerobic humus respiration by Shewanella cinica D14T].

Journal: Wei sheng wu xue bao = Acta microbiologica Sinica 20061201

Title: In vivo and in vitro metabolism of dexamethasone in the camel.

Journal: Veterinary journal (London, England : 1997) 20061101

Title: The H295R system for evaluation of endocrine-disrupting effects.

Journal: Ecotoxicology and environmental safety 20061101

Title: A patient with recurrent hypercortisolism after removal of an ACTH-secreting pituitary adenoma due to an adrenal macronodule.

Journal: Journal of endocrinological investigation 20061101

Title: Diminished cortisol levels in subordinate female marmosets are associated with altered central drive to the hypothalamic-pituitary-adrenal axis.

Journal: Biological psychiatry 20061015

Title: Role of IL-1 in poststroke depressive-like behavior in mice.

Journal: Biological psychiatry 20061015

Title: Mineralocorticoid receptor function in posttraumatic stress disorder after pretreatment with metyrapone.

Journal: Biological psychiatry 20061001

Title: [Properties of a triphenylmethane dyes decolorization enzyme (TpmD) from Aeromonas hydrophila strain DN322].

Journal: Wei sheng wu xue bao = Acta microbiologica Sinica 20061001

Title: [Adrenal insufficiency].

Journal: La Revue du praticien 20060915

Title: Glucocorticoid receptor and nuclear factor-kappa B interactions in restraint stress-mediated protection against acoustic trauma.

Journal: Endocrinology 20060901

Title: In vivo and mechanistic evidence of nuclear receptor CAR induction by artemisinin.

Journal: European journal of clinical investigation 20060901

Title: Induction of ROS formation, poly(ADP-ribose) polymerase-1 activation, and cell death by PCB126 and PCB153 in human T47D and MDA-MB-231 breast cancer cells.

Journal: Chemico-biological interactions 20060825

Title: CART peptide diurnal variations in blood and brain.

Journal: Peptides 20060801

Title: A novel role for IL-18 in corticosterone-mediated intestinal damage in a two-hit rodent model of alcohol intoxication and injury.

Journal: Journal of leukocyte biology 20060801

Title: Enhancement of DMNQ-induced hepatocyte toxicity by cytochrome P450 inhibition.

Journal: Toxicology and applied pharmacology 20060715

Title: Metyrapone improves endothelial dysfunction in patients with treated depression.

Journal: Journal of the American College of Cardiology 20060704

Title: Molecular characterization of cytochrome P450 genes in the polycyclic aromatic hydrocarbon degrading Mycobacterium vanbaalenii PYR-1.

Journal: Applied microbiology and biotechnology 20060701

Title: The role of corticosterone in human hypothalamic-pituitary-adrenal axis feedback.

Journal: Clinical endocrinology 20060701

Title: [Effects of blockage of hypothalamic-pituitary-adrenal cortex axis by metyrapone and Jiawei Xiaoyao Pills on immune system in mice exposed to chronic emotional stress].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20060701

Title: Neuroendocrine regulation of sleep disturbances in PTSD.

Journal: Annals of the New York Academy of Sciences 20060701

Title: Attenuating corticosterone levels on the day of memory assessment prevents chronic stress-induced impairments in spatial memory.

Journal: The European journal of neuroscience 20060701

Title: Up-regulation of the alligator CYP3A77 gene by toxaphene and dexamethasone and its short term effect on plasma testosterone concentrations.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20060630

Title: Restraint stress modulates glucocorticoid receptors and nuclear factor kappa B in the cochlea.

Journal: Neuroreport 20060626

Title: Rosiglitazone attenuates learning and memory deficits in Tg2576 Alzheimer mice.

Journal: Experimental neurology 20060601

Title: Inhibiting endogenous cortisol blunts the meal-entrained rise in serum leptin.

Journal: The Journal of clinical endocrinology and metabolism 20060601

Title: The role of glucocorticoids in the uncontrollable stress-induced potentiation of nucleus accumbens shell dopamine and conditioned place preference responses to morphine.

Journal: Psychoneuroendocrinology 20060601

Title: Future prospects in depression research.

Journal: Dialogues in clinical neuroscience 20060601

Title: [Corticosterone-producing adrenal tumor].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20060528

Title: [Adrenocortical adenoma].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20060528

Title: Systemic and intra-amygdala administration of glucocorticoid agonist and antagonist modulate extinction of conditioned fear.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060501

Title: Increased adrenal androgen secretion with inhibition of 11beta-hydroxylase in HIV-infected women.

Journal: American journal of physiology. Endocrinology and metabolism 20060501

Title: Lack of effect of metyrapone and exogenous cortisol on early porcine conceptus development.

Journal: Experimental physiology 20060501

Title: NF-kappaB mediated glucocorticoid response in the inner ear after acoustic trauma.

Journal: Journal of neuroscience research 20060501

Title: Increases in preproenkephalin mRNA levels in the Syrian hamster: the influence of glucocorticoids is dependent on age and tissue.

Journal: Brain research 20060501

Title: Why does acute hyperglycemia worsen the outcome of transient focal cerebral ischemia? Role of corticosteroids, inflammation, and protein O-glycosylation.

Journal: Stroke 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Antiglucocoticoid treatments for depression.

Journal: The Australian and New Zealand journal of psychiatry 20060501

Title: A case of low cortisol-binding globulin: use of plasma free cortisol in interpretation of hypothalamic-pituitary-adrenal axis tests.

Journal: Annals of clinical biochemistry 20060501

Title: Catecholamine response to methamphetamine is related to glucocorticoid levels but not to pleasurable subjective response.

Journal: Pharmacopsychiatry 20060501

Title: Corticotropin-releasing factor and neuropeptide Y mRNA levels are modified by glucocorticoids in rainbow trout, Oncorhynchus mykiss.

Journal: General and comparative endocrinology 20060401

Title: Antecedent hypercortisolemia is not primarily responsible for generating hypoglycemia-associated autonomic failure.

Journal: Diabetes 20060401

Title: Glucuronate, the precursor of vitamin C, is directly formed from UDP-glucuronate in liver.

Journal: The FEBS journal 20060401

Title: Mifepristone (RU-486) treatment for depression and psychosis: a review of the therapeutic implications.

Journal: Neuropsychiatric disease and treatment 20060301

Title: Uncoupled redox systems in the lumen of the endoplasmic reticulum. Pyridine nucleotides stay reduced in an oxidative environment.

Journal: The Journal of biological chemistry 20060224

Title: Stress-induced elevation of glucocorticoids increases microglia proliferation through NMDA receptor activation.

Journal: Journal of neuroimmunology 20060201

Title: Effect of neonatal isolation on outcome following neonatal seizures in rats--the role of corticosterone.

Journal: Epilepsy research 20060201

Title: [Effects of drugs on the adrenal cortex and its tumors].

Journal: Der Pathologe 20060201

Title: Cushing's syndrome during pregnancy secondary to adrenal adenoma: metyrapone treatment and laparoscopic adrenalectomy.

Journal: Journal of endocrinological investigation 20060201

Title: CYP2A5-mediated activation and early ultrastructural changes in the olfactory mucosa: studies on 2,6-dichlorophenyl methylsulfone.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060101

Title: Glucocorticoids in T cell apoptosis and function.

Journal: Cellular and molecular life sciences : CMLS 20060101

Title: Ectopic Cushing' syndrome caused by a neuroendocrine carcinoma of the mesentery.

Journal: BMC cancer 20060101

Title: [Effect of steroid biosynthesis modificators on the progesterone biotransformation by a recombinant yeasts expressing cytochrome P450c17].

Journal: Biomeditsinskaia khimiia 20060101

Title: Moderate exercise and chronic stress produce counteractive effects on different areas of the brain by acting through various neurotransmitter receptor subtypes: a hypothesis.

Journal: Theoretical biology & medical modelling 20060101

Title: Automatic recognition of topic-classified relations between prostate cancer and genes using MEDLINE abstracts.

Journal: BMC bioinformatics 20060101

Title: [Diagnosis and differential diagnosis of Cushing's syndrome].

Journal: Srpski arhiv za celokupno lekarstvo 20060101

Title: The hypothalamopituitary-adrenal axis and alcohol preference.

Journal: Brain research bulletin 20051230

Title: Effects of cortisol suppression on sleep-associated consolidation of neutral and emotional memory.

Journal: Biological psychiatry 20051201

Title: Oxytocin-induced labor augments IL-1beta-stimulated lung fluid absorption in fetal guinea pig lungs.

Journal: American journal of physiology. Lung cellular and molecular physiology 20051201

Title: Decreased response of plasma cortisol to intravenous metyrapone in ocular hypertension and primary open-angle glaucoma.

Journal: Journal of glaucoma 20051201

Title: Establishment of reference values for endocrine tests. Part IV: Adrenal insufficiency.

Journal: The Netherlands journal of medicine 20051201

Title: Olfactory neuroblastoma causing ectopic ACTH syndrome.

Journal: Endocrine journal 20051201

Title: Corticosteroids and endothelial dysfunction.

Journal: Vascular health and risk management 20051201

Title: Combination/augmentation strategies for improving the treatment of depression.

Journal: Neuropsychiatric disease and treatment 20051201

Title: ACTH deficiency in childhood cancer survivors.

Journal: Pediatric blood & cancer 20051101

Title: Expression of the human glucocorticoid receptor splice variants alpha, beta, and P in peripheral blood mononuclear leukocytes in healthy controls and in patients with hyper- and hypocortisolism.

Journal: The Journal of clinical endocrinology and metabolism 20051101

Title: Glucocorticoid receptor and treatment of psychotic major depression.

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20051101

Title: Structural and dynamical basis of broad substrate specificity, catalytic mechanism, and inhibition of cytochrome P450 3A4.

Journal: Journal of the American Chemical Society 20051005

Title: Effect of cytochrome P450 inhibitors and anticonvulsants on the acute toxicity of acrylonitrile.

Journal: Archives of toxicology 20051001

Title: Biodegradation of bisphenol A by cells and cell lysate from Sphingomonas sp. strain AO1.

Journal: Biodegradation 20051001

Title: Escalated aggression as a reward: corticosterone and GABA(A) receptor positive modulators in mice.

Journal: Psychopharmacology 20051001

Title: In-vitro cytotoxicity of ET-743 (Trabectedin, Yondelis), a marine anti-cancer drug, in the Hep G2 cell line: influence of cytochrome P450 and phase II inhibition, and cytochrome P450 induction.

Journal: Anti-cancer drugs 20051001

Title: An extra-adrenal abdominal pheochromocytoma causing ectopic ACTH syndrome.

Journal: American journal of hypertension 20051001

Title: Inhibition of cortisol biosynthesis decreases circulating leptin levels in obese humans.

Journal: The Journal of clinical endocrinology and metabolism 20050901

Title: Omega-oxygenation of the alkyl sidechain of linear alkylbenzenesulfonate (LAS) surfactant in Parvibaculum lavamentivorans(T).

Journal: Archives of microbiology 20050901

Title: Neuroendocrine predictors of the evolution of depression.

Journal: Dialogues in clinical neuroscience 20050901

Title: Behavioral specificity of non-genomic glucocorticoid effects in rats: effects on risk assessment in the elevated plus-maze and the open-field.

Journal: Hormones and behavior 20050801

Title: Metyrapone is an effective adjuvant treatment for major depression.

Journal: Evidence-based mental health 20050801

Title: [Urinary tetrahydro-11-deoxycortisol (THS)].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20050801

Title: Inhibition of cortisol production with metyrapone prevents mental stress-induced endothelial dysfunction and baroreflex impairment.

Journal: Journal of the American College of Cardiology 20050719

Title: The effects of cocaine on CART expression in the rat nucleus accumbens: a possible role for corticosterone.

Journal: European journal of pharmacology 20050704

Title: Corticosterone suppresses mesenteric lymph node T cells by inhibiting p38/ERK pathway and promotes bacterial translocation after alcohol and burn injury.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20050701

Title: Evaluation of GABAergic neuroactive steroid 3alpha-hydroxy-5alpha-pregnane-20-one as a neurobiological substrate for the anti-anxiety effect of ethanol in rats.

Journal: Psychopharmacology 20050701

Title: Joint synchrony of reciprocal hormonal signaling in human paradigms of both ACTH excess and cortisol depletion.

Journal: American journal of physiology. Endocrinology and metabolism 20050701

Title: Arachidonic acid induces neuronal death through lipoxygenase and cytochrome P450 rather than cyclooxygenase.

Journal: Journal of neuroscience research 20050701

Title: [Treatment with metyrapone of Cushing's syndrome revealing McCune-Albright syndrome].

Journal: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20050701

Title: Reduced capacity for the reactivation of glucocorticoids in rheumatoid arthritis synovial cells: possible role of the sympathetic nervous system?

Journal: Arthritis and rheumatism 20050601

Title: Periodic secretion of adrenocorticotropin in a patient with Cushing's disease manifested during pregnancy.

Journal: Endocrine journal 20050601

Title: Properties and regional expression of a CYP3A-like protein in channel catfish intestine.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20050515

Title: Surgical and pharmacological suppression of glucocorticoids prevents the enhancement of morphine conditioned place preference by uncontrollable stress in rats.

Journal: Psychopharmacology 20050501

Title: Psychological stress induces chemoresistance in breast cancer by upregulating mdr1.

Journal: Biochemical and biophysical research communications 20050415

Title: Effective NADH-dependent oxidation of 7beta-hydroxy-delta8-tetrahydrocannabinol to the corresponding ketone by Japanese monkey hepatic microsomes.

Journal: Biological & pharmaceutical bulletin 20050401

Title: Metyrapone and cocaine: a double-blind, placebo-controlled drug interaction study.

Journal: Pharmacology, biochemistry, and behavior 20050401

Title: Significance of endogenous glucocorticoid sensitivity for airway eosinophilia in a murine model of allergy.

Journal: Acta oto-laryngologica 20050401

Title: Hypothalamo-pituitary-adrenocortical axis in stress-susceptible and stress-resistant pigs: endocrine responses to corticotrophin-releasing factor and vasopressin.

Journal: Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie 20050401

Title: Interference of arachidonic acid and its metabolites with TNF-alpha release by ochratoxin A from rat liver.

Journal: Toxicology 20050330

Title: Declarative memory after stress in humans: differential involvement of the beta-adrenergic and corticosteroid systems.

Journal: The Journal of clinical endocrinology and metabolism 20050301

Title: Effect of corticosterone on CART peptide levels in rat blood.

Journal: Peptides 20050301

Title: Kinetic and binding studies with purified recombinant proteins ferredoxin reductase, ferredoxin and cytochrome P450 comprising the morpholine mono-oxygenase from Mycobacterium sp. strain HE5.

Journal: The FEBS journal 20050301

Title: Effect of combined treatment with imipramine and metyrapone on the immobility time, the activity of hypothalamo-pituitary-adrenocortical axis and immunological parameters in the forced swimming test in the rat.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20050301

Title: Inhibiting cortisol response accelerates recovery from a photic phase shift.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20050101

Title: Maternal low-protein diet in rat pregnancy programs blood pressure through sex-specific mechanisms.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20050101

Title: A single dose of metyrapone caused long-term dysregulation of the hypothalamic-pituitary-adrenal axis in the rat.

Journal: Neuroscience 20050101

Title: Effects of the cortisol synthesis inhibitor metyrapone on the response to carbon dioxide challenge in panic disorder.

Journal: Depression and anxiety 20050101

Title: Quantitative PCR assay for cytochromes P450 2B and 3A induction in rat precision-cut liver slices: correlation study with induction in vivo.

Journal: Journal of pharmacological and toxicological methods 20050101

Title: Efficient short-term control of hypercortisolaemia by low-dose etomidate in severe paediatric Cushing's disease.

Journal: Hormone research 20050101

Title: Heterophile antibodies may cause falsely lowered serum cortisol values.

Journal: Journal of endocrinological investigation 20050101

Title: Combined treatment with imipramine and metyrapone induces hippocampal and cortical brain-derived neurotrophic factor gene expression in rats.

Journal: Pharmacological reports : PR 20050101

Title: Metyrapone attenuates the sequential learning deficits but not monoamine depletions following d,l-fenfluramine administration to adult rats.

Journal: Synapse (New York, N.Y.) 20041215

Title: Metyrapone tests in patients with panic disorder.

Journal: Biological psychiatry 20041201

Title: Metyrapone as additive treatment in major depression: a double-blind and placebo-controlled trial.

Journal: Archives of general psychiatry 20041201

Title: Macronodular adrenocortical hyperplasia in a postmenopausal woman.

Journal: The Netherlands journal of medicine 20041201

Title: Behavioral effects of metyrapone on Pavlovian extinction.

Journal: Neuroscience letters 20041123

Title: Induction of bone-marrow eosinophilia in mice submitted to surgery is dependent on stress-induced secretion of glucocorticoids.

Journal: British journal of pharmacology 20041101

Title: Clinical features, diagnosis, treatment and molecular studies in paediatric Cushing's syndrome due to primary nodular adrenocortical hyperplasia.

Journal: Clinical endocrinology 20041101

Title: Metyrapone infusion stimulates adrenal growth without activating the cell cycle or the IGF system in the late gestation fetal sheep.

Journal: Endocrine research 20041101

Title: Essentiality of central GABAergic neuroactive steroid allopregnanolone for anticonvulsant action of fluoxetine against pentylenetetrazole-induced seizures in mice.

Journal: Brain research 20041008

Title: HPA axis activation in major depression and response to fluoxetine: a pilot study.

Journal: Psychoneuroendocrinology 20041001

Title: Stress and glucocorticoid inhibit apical GLUT2-trafficking and intestinal glucose absorption in rat small intestine.

Journal: The Journal of physiology 20041001

Title: Periconceptional undernutrition in sheep accelerates maturation of the fetal hypothalamic-pituitary-adrenal axis in late gestation.

Journal: Endocrinology 20040901

Title: Effect of single doses of dexamethasone and adrenocorticotrop hormone on serum bone markers in healthy subjects and in patients with adrenal incidentalomas and Cushing's syndrome.

Journal: Journal of endocrinological investigation 20040901

Title: Effects of beta-naphthoflavone, phenobarbital and dichlobenil on the drug-metabolizing system of liver and nasal mucosa of Italian water frogs.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20040825

Title: Overnight metyrapone and combined dexamethasone/metyrapone tests in post-traumatic stress disorder: preliminary findings.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20040801

Title: Differential actions of metyrapone on the fetal pituitary-adrenal axis in the sheep fetus in late gestation.

Journal: Biology of reproduction 20040801

Title: Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone.

Journal: Science (New York, N.Y.) 20040730

Title: Metyrapone for delirium due to Cushing's syndrome induced by occult ectopic adrenocorticotropic hormone secretion.

Journal: The Journal of clinical psychiatry 20040701

Title: Genomic and non-genomic effects of glucocorticoids on aggressive behavior in male rats.

Journal: Psychoneuroendocrinology 20040601

Title: Selective inhibition of CYP2B6-catalyzed bupropion hydroxylation in human liver microsomes in vitro.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040601

Title: Chronic glucocorticoid deficiency-induced abnormal aggression, autonomic hypoarousal, and social deficit in rats.

Journal: Journal of neuroendocrinology 20040601

Title: Role of Sp1, C/EBP alpha, HNF3, and PXR in the basal- and xenobiotic-mediated regulation of the CYP3A4 gene.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040501

Title: IL-1beta stimulates alveolar fluid absorption in fetal guinea pig lungs via the hypothalamus-pituitary-adrenal gland axis.

Journal: American journal of physiology. Lung cellular and molecular physiology 20040401

Title: Evidence of metyrapone reduction by two Mycobacterium strains shown by 1H NMR.

Journal: Biodegradation 20040401

Title: Microbial transformations of chalcones: hydroxylation, O-demethylation, and cyclization to flavanones.

Journal: Journal of natural products 20040401

Title: Differential effects of adrenergic and corticosteroid hormonal systems on human short- and long-term declarative memory for emotionally arousing material.

Journal: Behavioral neuroscience 20040401

Title: A facilitative role for corticosterone in the acquisition of a spatial task under moderate stress.

Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20040301

Title: Do smoking intensity-related differences in vigilance indicate altered glucocorticoid receptor sensitivity?

Journal: Addiction biology 20040301

Title: Spectroelectrochemistry of cytochrome P450cam.

Journal: Biochemical and biophysical research communications 20040213

Title: Comparison of in vitro activities of biotransformation enzymes in pig, cattle, goat and sheep.

Journal: Research in veterinary science 20040201

Title: Characterization of enzymes responsible for biotransformation of the new antileukotrienic drug quinlukast in rat liver microsomes and in primary cultures of rat hepatocytes.

Journal: The Journal of pharmacy and pharmacology 20040201

Title: Regulation of allergic lung inflammation in rats: interaction between estradiol and corticosterone.

Journal: Neuroimmunomodulation 20040101

Title: Clinical review: corticotherapy in sepsis.

Journal: Critical care (London, England) 20040101

Title: Investigation of the hypothalamo-pituitary-adrenal axis (HPA) by 1 microg ACTH test and metyrapone test in patients with primary fibromyalgia syndrome.

Journal: Journal of endocrinological investigation 20040101

Title: Effects of amphetamine on immune-mediated lung inflammatory response in rats.

Journal: Neuroimmunomodulation 20040101

Title: Ectopic Cushing's syndrome caused by an esthesioneuroblastoma.

Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20040101

Title: Role of adrenal gland hormones in the mechanism of antiulcer action of nimesulide and ranitidine.

Journal: Polish journal of pharmacology 20040101

Title: Effect of metyrapone supplementation on imipramine therapy in patients with treatment-resistant unipolar depression.

Journal: Polish journal of pharmacology 20040101

Title: Decreasing endogenous glucocorticoids alters the ability of bone marrow cells to produce nitric oxide in response to stimulating agents.

Journal: Cellular immunology 20040101

Title: [ACTH-dependent Cushing's syndrome: a revision of 43 cases].

Journal: Acta medica portuguesa 20040101

Title: Toluene monooxygenase from the fungus Cladosporium sphaerospermum.

Journal: Biochemical and biophysical research communications 20031212

Title: Cortisol feedback state governs adrenocorticotropin secretory-burst shape, frequency, and mass in a dual-waveform construct: time of day-dependent regulation.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20031101

Title: Glucocorticoids are involved in the long-term effects of a single immobilization stress on the hypothalamic-pituitary-adrenal axis.

Journal: Psychoneuroendocrinology 20031101

Title: Induction of ABCC3 (MRP3) by pregnane X receptor activators.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20031101

Title: Pathway-specific response to cortisol in the metabolism of catfish.

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20031101

Title: Sleep endocrine effects of the 11-beta-hydroxysteroiddehydrogenase inhibitor metyrapone.

Journal: Sleep 20031101

Title: The effect of intrafetal infusion of metyrapone on arterial blood pressure and on the arterial blood pressure response to angiotensin II in the sheep fetus during late gestation.

Journal: The Journal of physiology 20031015

Title: Nuclear receptors constitutive androstane receptor and pregnane X receptor activate a drug-responsive enhancer of the murine 5-aminolevulinic acid synthase gene.

Journal: The Journal of biological chemistry 20031010

Title: Circadian clock resetting by arousal in Syrian hamsters: the role of stress and activity.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20031001

Title: Endotoxin-induced shock in the pig--limited effects of low and high concentrations of inhaled nitric oxide.

Journal: Acta physiologica Scandinavica 20031001

Title: Mineralocorticoid receptor-mediated inhibition of the hypothalamic-pituitary-adrenal axis in aged humans.

Journal: The journals of gerontology. Series A, Biological sciences and medical sciences 20031001

Title: [How to plan glucocorticoid withdrawal: diagnostic and therapeutic strategies].

Journal: Praxis 20031001

Title: Modification of delayed radiation-induced reactions of duodenal vessels and mast cells in old rats.

Journal: Bulletin of experimental biology and medicine 20031001

Title: Rapid stimulation of free glucuronate formation by non-glucuronidable xenobiotics in isolated rat hepatocytes.

Journal: The Journal of biological chemistry 20030919

Title: Delta sleep response to metyrapone in post-traumatic stress disorder.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030901

Title: Altering cortisol level does not change the pleasurable effects of methamphetamine in humans.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030901

Title: A regulatory role for cortisol in muscle glycogen metabolism in rainbow trout Oncorhynchus mykiss Walbaum.

Journal: The Journal of experimental biology 20030901

Title: Interaction effects of corticosterone and experience on aggressive behavior in the green anole lizard.

Journal: Hormones and behavior 20030901

Title: The mineralocorticoid receptor agonist, fludrocortisone, inhibits pituitary-adrenal activity in humans after pre-treatment with metyrapone.

Journal: Life sciences 20030822

Title: Corticosterone enhances adrenocorticotropin-induced calcium signals in bovine adrenocortical cells.

Journal: Endocrinology 20030801

Title: Leptin distribution and metabolism in the pregnant rat: transplacental leptin passage increases in late gestation but is reduced by excess glucocorticoids.

Journal: Endocrinology 20030701

Title: Effect of cortisol on muscle sympathetic nerve activity in Pima Indians and Caucasians.

Journal: The Journal of clinical endocrinology and metabolism 20030701

Title: The role of CYP 1A1 in the in vitro metabolism of pregnenolone by the liver of rainbow trout embryos.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20030701

Title: Cell-specific activation of aflatoxin B1 correlates with presence of some cytochrome P450 enzymes in olfactory and respiratory tissues in horse.

Journal: Research in veterinary science 20030601

Title: Ultrastructure of the pineal gland after gamma-irradiation under conditions of inhibition of adrenocortical function.

Journal: Bulletin of experimental biology and medicine 20030601

Title: Mitochondrial and microsomal derived reactive oxygen species mediate apoptosis induced by transforming growth factor-beta1 in immortalized rat hepatocytes.

Journal: Journal of cellular biochemistry 20030515

Title: The glucose paradox of cerebral ischemia: evidence for corticosterone involvement.

Journal: Brain research 20030502

Title: Mifepristone or inhibition of 11beta-hydroxylase activity potentiates the sedating effects of the cannabinoid receptor-1 agonist Delta(9)-tetrahydrocannabinol in mice.

Journal: Neuroscience letters 20030501

Title: Corticotropin-releasing factor testing reveals a dose-dependent difference in methadone maintained vs control subjects.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030501

Title: Decreasing the threshold for thymocyte activation biases CD4+ T cells toward a regulatory (CD4+CD25+) lineage.

Journal: European journal of immunology 20030501

Title: Concurrent corticosteroid and phenanthrene transformation by filamentous fungus Cunninghamella elegans.

Journal: The Journal of steroid biochemistry and molecular biology 20030501

Title: Action of metyrapone and tetracosactrin to modify cisplatin-induced acute and delayed emesis in the ferret.

Journal: European journal of pharmacology 20030411

Title: Effects of anti-ecdysteroid quaternary derivatives of azole analogues of metyrapone on the post-embryonic development of the red cotton bug (Dysdercus cingulatus F).

Journal: Pest management science 20030401

Title: 11-hydroxylation in the biosynthesis of endogenous ouabain: multiple implications.

Journal: Annals of the New York Academy of Sciences 20030401

Title: Octreotide-sensitive ectopic ACTH production by islet cell carcinoma with multiple liver metastases.

Journal: Endocrine journal 20030401

Title: Influence of cortisol, gonadal steroids and an energy deficit on biochemical indicators of bone turnover in Swine.

Journal: Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20030301

Title: Hypothalamic-pituitary adrenal response to cholecystokinin-B receptor agonism is resistant to cortisol feedback inhibition.

Journal: Psychoneuroendocrinology 20030201

Title: In vitro metabolism of fenthion and fenthion sulfoxide by liver preparations of sea bream, goldfish, and rats.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030201

Title: Repeated, non-habituating stress suppresses inflammatory plasma extravasation by a novel, sympathoadrenal dependent mechanism.

Journal: The European journal of neuroscience 20030201

Title: 11beta-Hydroxysteroid dehydrogenase type 1: tissue-specific expression and reductive metabolism of some anti-insect agent azole analogues of metyrapone.

Journal: Chemico-biological interactions 20030201

Title: Exposure of brown trout Salmo trutta to a sublethal concentration of copper in soft acidic water: effects upon gas exchange and ammonia accumulation.

Journal: The Journal of experimental biology 20030101

Title: Catalytic activities of cytochrome P450 enzymes and UDP-glucuronosyltransferases involved in drug metabolism in rat everted sacs and intestinal microsomes.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20030101

Title: Metyrapone-induced glucocorticoid depletion modulates tyrosine hydroxylase and phenylethanolamine N-methyltransferase gene expression in the rat adrenal gland by a noncholinergic transsynaptic activation.

Journal: Journal of neuroendocrinology 20030101

Title: Adrenal-mediated rather than direct effects of nicotine as a basis of altered sex steroid synthesis in fetal and neonatal rat.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20030101

Title: Evidence of cytochrome P450-catalyzed cleavage of the ether bond of phenoxybutyrate herbicides in Rhodococcus erythropolis K2-3.

Journal: Biodegradation 20030101

Title: Isomer-specific bioactivation and toxicity of dichlorophenyl methylsulphone in rat olfactory mucosa.

Journal: Toxicologic pathology 20030101

Title: Resolution of Cushing's disease followed by secondary adrenal insufficiency after anticoagulant-associated pituitary hemorrhage: report of a case and review of the literature.

Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20030101

Title: Significance of low-dose and standard-dose ACTH tests compared to overnight metyrapone test in the diagnosis of adrenal insufficiency in childhood.

Journal: Hormone research 20030101

Title: The assessment of the hypothalamo-pituitary-adrenal axis in pituitary disease: are there short cuts?

Journal: Journal of endocrinological investigation 20030101

Title: Dynamic tests in the diagnosis and differential diagnosis of Cushing's syndrome.

Journal: Journal of endocrinological investigation 20030101

Title: Dynamic evaluation of adrenal hypofunction.

Journal: Journal of endocrinological investigation 20030101

Title: Neural immune pathways and their connection to inflammatory diseases.

Journal: Arthritis research & therapy 20030101

Title: Effects of combined treatment with imipramine and metyrapone in the forced swimming test in rats. Behavioral and pharmacokinetic studies.

Journal: Polish journal of pharmacology 20030101

Title: Medical treatment of hyperadrenocorticism in the dog.

Journal: Australian veterinary journal 20030101

Title: Receptor-dependent regulation of the CYP3A4 gene.

Journal: Toxicology 20021227

Title: Glucocorticoid receptor deficient thymic and peripheral T cells develop normally in adult mice.

Journal: European journal of immunology 20021201

Title: Combined stimulation of adrenocorticotropin and compound-S by single dose metyrapone test as an outpatient procedure to assess hypothalamic-pituitary-adrenal function.

Journal: The Journal of clinical endocrinology and metabolism 20021201

Title: Behavioral action of ethanol in Porsolt's forced swim test: modulation by 3 alpha-hydroxy-5 alpha-pregnan-20-one.

Journal: Neuropharmacology 20021201

Title: Cushing's syndrome during pregnancy: curative adrenalectomy at 31 weeks gestation.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20021115

Title: [Cushing's syndrome during pregnancy].

Journal: Presse medicale (Paris, France : 1983) 20021109

Title: Leukemia inhibitory factor is a mediator of Escherichia coli lipopolysaccharide-induced acute thymic atrophy.

Journal: European journal of immunology 20021101

Title: Corticosteroids and pregnancy.

Journal: Seminars in reproductive medicine 20021101

Title: Estrogen-induced gonadotropin surge in rhesus monkeys is not inhibited by cortisol synthesis inhibition or hypoglycemia.

Journal: Endocrine 20021101

Title: The contribution of cytochrome P-450 isoenzymes to the metabolism of phenothiazine neuroleptics.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20021001

Title: Determination of the plasma levels of metyrapone and its enantiomeric metyrapol metabolites by direct plasma injection and multidimensional achiral-chiral chromatography.

Journal: Chirality 20021001

Title: Does cortisol mediate endotoxin-induced inhibition of pulsatile luteinizing hormone and gonadotropin-releasing hormone secretion?

Journal: Endocrinology 20021001

Title: Leptin receptor expression in the rat placenta: changes in ob-ra, ob-rb, and ob-re with gestational age and suppression by glucocorticoids.

Journal: Biology of reproduction 20021001

Title: The stimulatory effect of canrenoate, a mineralocorticoid antagonist, on the activity of the hypothalamus-pituitary-adrenal axis is abolished by alprazolam, a benzodiazepine, in humans.

Journal: The Journal of clinical endocrinology and metabolism 20021001

Title: The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism.

Journal: Endocrine reviews 20021001

Title: Spectroscopic studies of peroxyacetic acid reaction intermediates of cytochrome P450cam and chloroperoxidase.

Journal: Journal of inorganic biochemistry 20020920

Title: Preirradiation endocrinopathies in pediatric brain tumor patients determined by dynamic tests of endocrine function.

Journal: International journal of radiation oncology, biology, physics 20020901

Title: Responses of the bronchial and pulmonary circulations to short-term nitric oxide inhalation before and after endotoxaemia in the pig.

Journal: Acta physiologica Scandinavica 20020901

Title: Deoxysarpagine hydroxylase--a novel enzyme closing a short side pathway of alkaloid biosynthesis in Rauvolfia.

Journal: Bioorganic & medicinal chemistry 20020801

Title: Acute modulation of aged human memory by pharmacological manipulation of glucocorticoids.

Journal: The Journal of clinical endocrinology and metabolism 20020801

Title: Target cells for cytochrome p450-catalysed irreversible binding of 7,12-dimethylbenz[a]anthracene (DMBA) in rodent adrenal glands.

Journal: Archives of toxicology 20020801

Title: Evidence that metyrapone can act as a stressor: effect on pituitary-adrenal hormones, plasma glucose and brain c-fos induction.

Journal: The European journal of neuroscience 20020801

Title: Metyrapone-induced corticosterone deficiency impairs glucose oxidation and steroidogenesis in Leydig cells of adult albino rats.

Journal: Endocrine journal 20020801

Title: Functional scintigraphy of the adrenal gland.

Journal: European journal of endocrinology 20020701

Title: Metyrapone for Cushing's syndrome.

Journal: The American journal of psychiatry 20020701

Title: Brain HSP70 mRNA expression is linked with plasma cortisol levels in goldfish (Carassius auratus) exposed to a potential predator.

Journal: Zoological science 20020701

Title: The role of cortisol suppression on craving for and satisfaction from nicotine in high and low impulsive subjects.

Journal: Human psychopharmacology 20020701

Title: The neurobiology of opioid dependence: implications for treatment.

Journal: Science & practice perspectives 20020701

Title: The lethal form of Cushing's in 7B2 null mice is caused by multiple metabolic and hormonal abnormalities.

Journal: Endocrinology 20020601

Title: Glucocorticoid replacement in pituitary surgery: guidelines for perioperative assessment and management.

Journal: The Journal of clinical endocrinology and metabolism 20020601

Title: Small changes in whole-body corticosterone content affect larval Rana pipiens fitness components.

Journal: General and comparative endocrinology 20020601

Title: Erratum to 'CNS drugs in Cushing's disease: pathophysiological and therapeutic implications for mood disorders' [Prog. Neuro-Psycol. Biol. Psychiatry, 26, 763 (2002)].

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20020601

Title: A spectrophotometric method to monitor the catalytic activity of microsomal cytochrome P-450 IIB1/2: comparison with fluorometric assay.

Journal: Indian journal of biochemistry & biophysics 20020601

Title: Transcriptional activation of cytochrome P450 CYP2C45 by drugs is mediated by the chicken xenobiotic receptor (CXR) interacting with a phenobarbital response enhancer unit.

Journal: The Journal of biological chemistry 20020503

Title: Residual symptoms in depression an emerging therapeutic concept.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20020501

Title: Evidence for glucose-6-phosphate transport in rat liver microsomes.

Journal: FEBS letters 20020424

Title: The modulatory effects of corticosteroids on cognition: studies in young human populations.

Journal: Psychoneuroendocrinology 20020401

Title: Evidence for involvement of glucocorticoid response in the hippocampal changes in aged molarless SAMP8 mice.

Journal: Behavioural brain research 20020401

Title: Effects of 3-MeSO2-DDE and some CYP inhibitors on glucocorticoid steroidogenesis in the H295R human adrenocortical carcinoma cell line.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20020401

Title: The oxidative biotransformation of losoxantrone (CI-941).

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020401

Title: Sympathetic nervous system plays a major role in acute cold/restraint stress inhibition of host resistance to Listeria monocytogenes.

Journal: Journal of neuroimmunology 20020401

Title: The low-dose ACTH test does not provide a useful assessment of the hypothalamic-pituitary-adrenal axis in secondary adrenal insufficiency.

Journal: Clinical endocrinology 20020401

Title: Induction of cardiac cytochrome p450 in cocaine-treated mice.

Journal: Experimental biology and medicine (Maywood, N.J.) 20020301

Title: Cytochrome P450-catalyzed binding of 3-methylsulfonyl-DDE and o,p'-DDD in human adrenal zona fasciculata/reticularis.

Journal: The Journal of clinical endocrinology and metabolism 20020301

Title: The clinical pharmacology of depressive states.

Journal: Dialogues in clinical neuroscience 20020301

Title: Reductive metabolism of p,p'-DDT and o,p'-DDT by rat liver cytochrome P450.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020201

Title: Production of carbon monoxide by cytochrome P450 during iron-dependent lipid peroxidation.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20020201

Title: Glucocorticoid involvement in memory formation in a rat model for traumatic memory.

Journal: Stress (Amsterdam, Netherlands) 20020201

Title: Biosynthesis of beta-substituted furan skeleton in the lower furanoterpenoids: a model study.

Journal: Biochemical and biophysical research communications 20020111

Title: A pharmacophore for human pregnane X receptor ligands.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020101

Title: Role for corticoids in mediating the response of Rana pipiens tadpoles to intraspecific competition.

Journal: The Journal of experimental zoology 20020101

Title: Circulating corticosterone alters the rate of neuropathological and behavioral changes induced by trimethyltin in rats.

Journal: Experimental neurology 20020101

Title: A lipid A analog ONO-4007 induces tolerance to plasma leakage in mice.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20020101

Title: Ectopic ACTH-syndrome due to a thymic carcinoid tumor.

Journal: Acta clinica Belgica 20020101

Title: Evidence that RDX biodegradation by Rhodococcus strain DN22 is plasmid-borne and involves a cytochrome p-450.

Journal: Journal of applied microbiology 20020101

Title: Bench-to-bedside review: a possible resolution of the glucose paradox of cerebral ischemia.

Journal: Critical care (London, England) 20020101

Title: Medical therapy of Cushing's disease.

Journal: Pituitary 20020101

Title: Medical management of pituitary adenomas: the special case of management of the pregnant woman.

Journal: Pituitary 20020101

Title: Classic and recent etiologies of Cushing's syndrome: diagnosis and therapy.

Journal: Treatments in endocrinology 20020101

Title: Metabolism of territrem a by liver microsomes of Wistar rats: identification of the metabolites and their metabolic sequence.

Journal: Journal of toxicology and environmental health. Part A 20011207

Title: Induction by xenobiotics of phase I and phase II enzyme activities in the human keratinocyte cell line NCTC 2544.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20011201

Title: Memory retrieval impairment induced by hippocampal CA3 lesions is blocked by adrenocortical suppression.

Journal: Nature neuroscience 20011201

Title: Preischemic hyperglycemia-aggravated damage: evidence that lactate utilization is beneficial and glucose-induced corticosterone release is detrimental.

Journal: Journal of neuroscience research 20011201

Title: Rational, effective metyrapone treatment of ACTH-independent bilateral macronodular adrenocortical hyperplasia (AIMAH).

Journal: Endocrine journal 20011201

Title: Comparative metabolism, covalent binding and toxicity of BHT congeners in rat liver slices.

Journal: Chemico-biological interactions 20011128

Title: The role of adrenal corticosteroids in induction of micronuclei by morphine.

Journal: Mutation research 20011115

Title: Corticotropin secretory dynamics in humans under low glucocorticoid feedback.

Journal: The Journal of clinical endocrinology and metabolism 20011101

Title: Effects of diethylstilbestrol on the cytogenesis of prolactin cells in the pars distalis of the pituitary gland of the mouse.

Journal: Cell and tissue research 20011101

Title: Oxyphil metaplasia of adrenal cortex secondary to metyrapone therapy.

Journal: Histopathology 20011101

Title: Protective effects of 5-HT1A receptor agonists against emotional changes produced by stress stimuli are related to their neuroendocrine effects.

Journal: British journal of pharmacology 20011001

Title: No effect of the cortisol-synthesis inhibitor metyrapone on alcohol drinking: a pilot study.

Journal: Alcohol (Fayetteville, N.Y.) 20011001

Title: Glucocorticoids impair fetal beta-cell development in rats.

Journal: American journal of physiology. Endocrinology and metabolism 20010901

Title: Conservation of signaling pathways of xenobiotic-sensing orphan nuclear receptors, chicken xenobiotic receptor, constitutive androstane receptor, and pregnane X receptor, from birds to humans.

Journal: Molecular endocrinology (Baltimore, Md.) 20010901

Title: 7-Deoxyloganin 7-hydroxylase in Lonicera japonica cell cultures.

Journal: Phytochemistry 20010901

Title: Primary culture system of adrenocortical cells from dogs to evaluate direct effects of chemicals on steroidogenesis.

Journal: Toxicology 20010828

Title: Glucocorticoid feedback sensitivity and adrenocortical responsiveness in posttraumatic stress disorder.

Journal: Biological psychiatry 20010815

Title: Lung carcinoid related Cushing's syndrome: report of three cases and review of the literature.

Journal: Postgraduate medical journal 20010701

Title: Prodissociative effects of metyrapone.

Journal: The American journal of psychiatry 20010701

Title: Do circulating plasma AVT and/or cortisol levels control pulsatile urea excretion in the gulf toadfish (Opsanus beta)?

Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20010701

Title: Effects of intranasal corticosteroids on the hypothalamic-pituitary-adrenal axis in children.

Journal: The Journal of allergy and clinical immunology 20010701

Title: In vitro metabolism of 14C-moxidectin by hepatic microsomes from various species.

Journal: Veterinary research communications 20010701

Title: Involvement of adrenal and thyroid activity in the annual testicular regression of red headed bunting (Emberiza bruniceps).

Journal: Journal of environmental biology 20010701

Title: Modulation of cyclophosphamide-based cytochrome P450 gene therapy using liver P450 inhibitors.

Journal: Cancer gene therapy 20010601

Title: Involvement of the cholinergic pathway in the pathogenesis of pituitary Cushing's syndrome.

Journal: Endocrine journal 20010601

Title: Role of crotoxin, a phospholipase A2 isolated from Crotalus durissus terrificus snake venom, on inflammatory and immune reactions.

Journal: Mediators of inflammation 20010601

Title: Cold-induced increment in rat adrenal gland type II deiodinase is corticosterone dependent.

Journal: Endocrine 20010601

Title: Pharmacological suppression of corticosterone secretion in response to a physical stressor does not prevent the delayed persistent increase in circulating basal corticosterone concentration.

Journal: Stress (Amsterdam, Netherlands) 20010601

Title: Altered HPA axis responsivity to metyrapone testing in methadone maintained former heroin addicts with ongoing cocaine addiction.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010501

Title: The role of glutathione reductase in the cytotoxicity of chromium (VI) in isolated rat hepatocytes.

Journal: Chemico-biological interactions 20010416

Title: Bioactivation and cytotoxicity of 1,1-dichloro-2,2,2-trifluoroethane (HCFC-123) in isolated rat hepatocytes.

Journal: Pharmacology & toxicology 20010401

Title: Diagnosis of adrenal cortical dysfunction by liquid chromatography-tandem mass spectrometry.

Journal: Annals of clinical and laboratory science 20010401

Title: Cytochrome P450 1A1 and 4A activities in isolated rat spleen lymphocytes.

Journal: Die Pharmazie 20010401

Title: Appetite-suppressing effects of urotensin I and corticotropin-releasing hormone in goldfish (Carassius auratus).

Journal: Neuroendocrinology 20010401

Title: Glucocorticoid and mineralocorticoid receptors are involved in the facilitation of anxiety-like response induced by restraint.

Journal: Neuroendocrinology 20010401

Title: Isolation and characterization of two aerobic bacterial strains that completely degrade ethyl tert-butyl ether (ETBE).

Journal: Applied microbiology and biotechnology 20010401

Title: Fatal liver failure due to ketoconazole treatment of a girl with Cushing's syndrome.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20010301

Title: Species- and tissue-specific physiological regulation of vasopressin mRNA poly(A) tail length.

Journal: Physiological genomics 20010207

Title: Long term modulation of the HPA axis by the hippocampus. Behavioral, biochemical and immunological endpoints in rats exposed to chronic mild stress.

Journal: Psychoneuroendocrinology 20010201

Title: Human glucocorticoid feedback inhibition is reduced in older individuals: evening study.

Journal: The Journal of clinical endocrinology and metabolism 20010201

Title: Recurrent ACTH-independent Cushing's syndrome in multiple pregnancies and its treatment with metyrapone.

Journal: Clinical endocrinology 20010201

Title: Adrenal insufficiency in HIV infection: a review and recommendations.

Journal: The American journal of the medical sciences 20010201

Title: Irreversible binding and adrenocorticolytic activity of the DDT metabolite 3-methylsulfonyl-DDE examined in tissue-slice culture.

Journal: Environmental health perspectives 20010201

Title: A novel drug-regulated gene expression system based on the nuclear receptor constitutive androstane receptor (CAR).

Journal: Pharmaceutical research 20010201

Title: Bioactivation to free radicals and cytotoxicity of 1,1-dichloro-1-fluoroethane (HCFC-141b).

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20010201

Title: Human cervical tissue metabolizes the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, via alpha-hydroxylation and carbonyl reduction pathways.

Journal: Carcinogenesis 20010101

Title: Interaction between the adrenal and the pineal gland in chronic experimental inflammation induced by BCG in mice.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20010101

Title: Pathogenesis of carbon tetrachloride-induced hepatocyte injury bioactivation of CCI4 by cytochrome P450 and effects on lipid homeostasis.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20010101

Title: Psychiatric disorders associated with Cushing's syndrome. Epidemiology, pathophysiology and treatment.

Journal: CNS drugs 20010101

Title: Biology of posttraumatic stress disorder.

Journal: The Journal of clinical psychiatry 20010101

Title: The existence and significance of redox-cycling ubiquinone in lysosomes.

Journal: Protoplasma 20010101

Title: [Pituitary function after transsphenoidal surgery for pituitary adenoma].

Journal: Przeglad lekarski 20010101

Title: Metyrapone reveals that previous chronic stress differentially impairs hippocampal-dependent memory.

Journal: Stress (Amsterdam, Netherlands) 20010101

Title: In the search for specific inhibitors of human 11beta-hydroxysteroid-dehydrogenases (11beta-HSDs): chenodeoxycholic acid selectively inhibits 11beta-HSD-I.

Journal: European journal of endocrinology 20000201

Title: A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 19990301

Title: Functional maturation of the primate fetal adrenal in vivo: 3. Specific zonal localization and developmental regulation of CYP21A2 (P450c21) and CYP11B1/CYP11B2 (P450c11/aldosterone synthase) lead to integrated concept of zonal and temporal steroid biosynthesis.

Journal: Endocrinology 19981201

Title: A case of Cushing's syndrome due to ACTH-independent bilateral macronodular hyperplasia associated with excessive secretion of mineralocorticoids.

Journal: Endocrine journal 19980801

Title: Thiomorpholine and morpholine oxidation by a cytochrome P450 in Mycobacterium aurum MO1. Evidence of the intermediates by in situ 1H NMR.

Journal: Biodegradation 19980101

Title: Studies on the relationships between 7 alpha-hydroxylation and the ability of 25- and 27-hydroxycholesterol to suppress the activity of HMG-CoA reductase.

Journal: Biochimica et biophysica acta 19970218

Title: Styrene metabolism in Exophiala jeanselmei and involvement of a cytochrome P-450-dependent styrene monooxygenase.

Journal: Applied and environmental microbiology 19960401

Title: Sensitization of human breast cancer cells to cyclophosphamide and ifosfamide by transfer of a liver cytochrome P450 gene.

Journal: Cancer research 19960315

Title: Dog liver microsomal P450 enzyme-mediated toluene biotransformation.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 19951101

Title: Intratumoral activation and enhanced chemotherapeutic effect of oxazaphosphorines following cytochrome P-450 gene transfer: development of a combined chemotherapy/cancer gene therapy strategy.

Journal: Cancer research 19950201

Title: p-Dichlorobenzene-induced hepatotoxicity in mice depleted of glutathione by treatment with buthionine sulfoximine.

Journal: Toxicology 19940101

Title: Halothane-induced liver injury as a consequence of enhanced microsomal lipid peroxidation in guinea pigs.

Journal: Research communications in chemical pathology and pharmacology 19880801

Title: [Hypertension in rats caused by metyrapone and heat-stress treatment].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 19850901

Title: Metyrapone-induced cardiovascular degenerative changes in non-arteriosclerotic and arteriosclerotic rats.

Journal: British journal of experimental pathology 19780201

Title: Cytochrome P-450 for 11beta- and 18-hydroxylase activities of bovine adrenocortical mitochondria: one enzyme or two?

Journal: Biochemistry 19780110

Title: Inhibition by metyrapone of convulsions and storage of brain glycogen in mice induced by methionine sulfoximine (MSO).

Journal: Brain research 19770603

Title: Mineralocorticoid hypertension in childhood.

Journal: Mayo Clinic proceedings 19770501

Title: Evidence for an unidentified ACTH-induced steroid hormone causing hypertension.

Journal: The Journal of clinical endocrinology and metabolism 19761201

Title: Hemodynamic role of extracellular fluid in hypertension.

Journal: Circulation research 19760601

Title: Further studies of metyrapone effects upon anilide hydroxylation.

Journal: Drug metabolism and disposition: the biological fate of chemicals 19750101

Title: Adverse effects of large doses of medroxyprogesterone (MPA) in idiopathic isosexual precocity.

Journal: The Journal of pediatrics 19711201

Title: [Vertigo caused by SU 4885 (drug used in the hypophyseal function test)].

Journal: Jibi inkoka Otolaryngology 19710301

Title: 'Selective' pituitary insufficiency secondary to busulfan.

Journal: Annals of internal medicine 19670801

Title: Roozendaal B, et al. Dose-dependent suppression of adrenocortical activity with metyrapone: effects on emotion and memory. Psychoneuroendocrinology. 1996 Nov;21(8):681-93.

Title: Jahn H, et al. Metyrapone as additive treatment in major depression: a double-blind and placebo-controlled trial. Arch Gen Psychiatry. 2004 Dec;61(12):1235-44.

Title: Daniel E, et al. Effectiveness of Metyrapone in Treating Cushing's Syndrome: A Retrospective Multicenter Study in 195 Patients. J Clin Endocrinol Metab. 2015 Nov;100(11):4146-54.

Title: Peterson JA, Ullrich V, Hildebrandt AG. Methyrapone interaction with Pseudomonas putida cytochrome P-405. Arch Biochem Biophys. 1971 Aug;145(2):531-42.

Title: Holczer M, et al. A Comprehensive Systems Biological Study of Autophagy-Apoptosis Crosstalk during Endoplasmic Reticulum Stress. Biomed Res Int. 2015;2015:319589.

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Tags:54-36-4 Molecular Formula|54-36-4 MDL|54-36-4 SMILES|54-36-4 METYRAPONE |Heterocyclic_Building_Blocks