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545-46-0,MFCD00009620
Catalog No.:AA01CCML

545-46-0 | Urs-12-ene-3,28-diol, (3b)-

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10mg
≥95%
in stock  
$58.00   $40.00
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25mg
≥95%
in stock  
$128.00   $89.00
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50mg
≥95%
in stock  
$239.00   $167.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01CCML
Chemical Name:
Urs-12-ene-3,28-diol, (3b)-
CAS Number:
545-46-0
Molecular Formula:
C30H50O2
Molecular Weight:
442.7168
MDL Number:
MFCD00009620
SMILES:
OC[C@@]12CC[C@H]([C@@H]([C@H]2C2=CC[C@H]3[C@@]([C@@]2(CC1)C)(C)CC[C@@H]1[C@]3(C)CC[C@@H](C1(C)C)O)C)C
Properties
Computed Properties
 
Complexity:
799  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
10  
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
7.4  

Literature

Title: Study of skin anti-ageing and anti-inflammatory effects of dihydroquercetin, natural triterpenoids, and their synthetic derivatives.

Journal: Bioorganicheskaia khimiia 20120101

Title: CYP716A subfamily members are multifunctional oxidases in triterpenoid biosynthesis.

Journal: Plant & cell physiology 20111201

Title: Antibacterial properties of compounds isolated from Carpobrotus edulis.

Journal: International journal of antimicrobial agents 20110501

Title: [Studies on the chemical constituents of Coleus forskohlii transplanted in Tongcheng and their antitumor activity].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20110301

Title: [Synthesis and antitumor activity of betulin, erythrodiol and uvaol aminopropoxy derivatives].

Journal: Bioorganicheskaia khimiia 20110101

Title: Constituents of Carpobrotus edulis inhibit P-glycoprotein of MDR1-transfected mouse lymphoma cells.

Journal: Anticancer research 20100301

Title: 11beta-Hydroxysteroid dehydrogenase 1 inhibiting constituents from Eriobotrya japonica revealed by bioactivity-guided isolation and computational approaches.

Journal: Bioorganic & medicinal chemistry 20100215

Title: Structure-activity relationship study of betulinic acid, a novel and selective TGR5 agonist, and its synthetic derivatives: potential impact in diabetes.

Journal: Journal of medicinal chemistry 20100114

Title: Chemical Constituents of the Roots of Euphorbia micractina.

Journal: Journal of natural products 20090901

Title: Natural triterpenic diols promote apoptosis in astrocytoma cells through ROS-mediated mitochondrial depolarization and JNK activation.

Journal: PloS one 20090101

Title: A new monoterpene alkaloid and other constituents of Plumeria acutifolia.

Journal: Planta medica 20081101

Title: Triterpenoids from the leaves of Diospyros kaki (persimmon) and their inhibitory effects on protein tyrosine phosphatase 1B.

Journal: Journal of natural products 20081001

Title: Antimicrobial triterpenoids from Vladimiria muliensis.

Journal: Journal of natural products 20080401

Title: [Studies on chemical constituents of in herb Pyrola calliatha].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070901

Title: [Studies on triterpenoid constituents in leaf of Ilex pernyi].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070901

Title: Antitrypanosomal activity of triterpenoids and sterols from the leaves of Strychnos spinosa and related compounds.

Journal: Journal of natural products 20070801

Title: Modulation of cytokine secretion by pentacyclic triterpenes from olive pomace oil in human mononuclear cells.

Journal: Cytokine 20061201

Title: Three new triterpenes from Nerium oleander and biological activity of the isolated compounds.

Journal: Journal of natural products 20050201

Title: Antitubercular activity of triterpenoids from Asteraceae flowers.

Journal: Biological & pharmaceutical bulletin 20050101

Title: Triterpenoids from Brazilian Ilex species and their in vitro antitrypanosomal activity.

Journal: Journal of natural products 20041001

Title: Chemical constituents from the leaves of Psidium guajava.

Journal: Natural product research 20040401

Title: Cardiotonic and antidysrhythmic effects of oleanolic and ursolic acids, methyl maslinate and uvaol.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20040201

Title: Differentiation- and apoptosis-inducing activities by pentacyclic triterpenes on a mouse melanoma cell line.

Journal: Journal of natural products 20020501

Title: Antimycobacterial plant terpenoids.

Journal: Planta medica 20011101

Title: Inhibitory effects of triterpenoids and sterols on human immunodeficiency virus-1 reverse transcriptase.

Journal: Lipids 20010501

Title: Inhibitory effect of triterpenes from Crataegus pinatifida on HIV-I protease.

Journal: Planta medica 19990501

Title: Triterpenes as potential dimerization inhibitors of HIV-1 protease.

Journal: Biochemical and biophysical research communications 19961014

Title: Agra LC, et al. Uvaol attenuates pleuritis and eosinophilic inflammation in ovalbumin-induced allergy in mice. Eur J Pharmacol. 2016 Jun 5;780:232-42.

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