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Title: Host cells participate in the in vitro effects of novel diamidine analogues against tachyzoites of the intracellular apicomplexan parasites Neospora caninum and Toxoplasma gondii.
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Title: Human enteric microsomal CYP4F enzymes O-demethylate the antiparasitic prodrug pafuramidine.
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Title: Multidrug-binding transcription factor QacR binds the bivalent aromatic diamidines DB75 and DB359 in multiple positions.
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Title: Diamidines as antitrypanosomal, antileishmanial and antimalarial agents.
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Title: Inhibitory effect of dicationic diphenylfurans on production of type I collagen by human fibroblasts and activated hepatic stellate cells.
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Title: Thiophene-based diamidine forms a 'super' at binding minor groove agent.
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Title: Phenyl substitution of furamidine markedly potentiates its anti-parasitic activity against Trypanosoma cruzi and Leishmania amazonensis.
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Title: DB-289 Immtech International.
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Title: The activity of diguanidino and 'reversed' diamidino 2,5-diarylfurans versus Trypanosoma cruzi and Leishmania donovani.
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Title: Distribution of furamidine analogues in tumor cells: targeting of the nucleus or mitochondria depending on the amidine substitution.
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Title: Enhanced permeability of the antimicrobial agent 2,5-bis(4-amidinophenyl)furan across Caco-2 cell monolayers via its methylamidoidme prodrug.
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Title: Distribution of furamidine analogues in tumor cells: influence of the number of positive charges.
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Title: Influence of compound structure on affinity, sequence selectivity, and mode of binding to DNA for unfused aromatic dications related to furamidine.
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Title: Comparative thermodynamics for monomer and dimer sequence-dependent binding of a heterocyclic dication in the DNA minor groove.
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Title: Characterizing the fragmentation of 2,5-bis (4-amidinophenyl)furan-bis-O-methylamidoxime and selected metabolites using ion trap mass spectrometry.
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Title: Recognition of ATGA sequences by the unfused aromatic dication DB293 forming stacked dimers in the DNA minor groove.
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Title: Diguanidino and 'reversed' diamidino 2,5-diarylfurans as antimicrobial agents.
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Title: Inhibition of the HIV-1 rev-RRE complex formation by unfused aromatic cations.
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Title: Prodrugs for amidines: synthesis and anti-Pneumocystis carinii activity of carbamates of 2,5-bis(4-amidinophenyl)furan.
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Title: Aminooxypentane-RANTES, an inhibitor of R5 human immunodeficiency virus type 1, increases the interferon gamma to interleukin 10 ratio without impairing cellular proliferation.
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Title: Pentamidine is a potent inhibitor of [3H]idazoxan binding to imidazoline I2 receptors.
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Title: Extended aromatic furan amidino derivatives as anti-Pneumocystis carinii agents.
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Title: Dicationic furans inhibit development of Cryptosporidium parvum in HSD/ICR suckling Swiss mice.
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Title: 2,5-bis[4-(N-alkylamidino)phenyl]furans as anti-Pneumocystis carinii agents.
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Title: Identification and characterization of an endo/exonuclease in Pneumocystis carinii that is inhibited by dicationic diarylfurans with efficacy against Pneumocystis pneumonia.
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Title: Inhibition of HIV-1 Rev-RRE interaction by diphenylfuran derivatives.
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