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5704-04-1,MFCD00004277
Catalog No.:AA003UY4

5704-04-1 | Tricine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10g
98%
in stock  
$9.00   $7.00
- +
100g
98%
in stock  
$37.00   $26.00
- +
500g
98%
in stock  
$112.00   $78.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003UY4
Chemical Name:
Tricine
CAS Number:
5704-04-1
Molecular Formula:
C6H13NO5
Molecular Weight:
179.1711
MDL Number:
MFCD00004277
SMILES:
OCC(NCC(=O)O)(CO)CO
NSC Number:
369995
Properties
Properties
 
BP:
500.9 °C at 760 mmHg  
Form:
Solid  
MP:
186-188 °C (dec.);  
Refractive Index:
1.4240 (estimate)  
Solubility:
H2O: 4 M at 20 °C, clear, colorless  
Storage:
Room Temperature;Light sensitive;Inert atmosphere;  

Computed Properties
 
Complexity:
137  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
6  
XLogP3:
-5.1  

Downstream Synthesis Route

[1]JournalofOrganicChemistry,1986,vol.51,p.4866-4872

64-17-5    5704-04-1   
C8H17NO5 

[1]Patent:US6346547,2002,B1.Locationinpatent:Pagecolumn17

sodium99Tcpertechnetate 
  139-13-9    5704-04-1   
(99m)Tc(HYNIC-Lys(OMe)-NIC)(tricine) 

[1]Patent:US2005/10038,2005,A1.Locationinpatent:Page43

N-ε-(picolinyl)-N-α-(6-(2-(2-sulfonatobenzaldehyde)hydrazono)nicotinyl)lysinemethylester 
 
sodium99Tcpertechnetate 
  5704-04-1   
99mTc(HYNIC-Lys(OMe)-Pic)(tricine) 

[1]Patent:US2005/10038,2005,A1.Locationinpatent:Page44

1-(N-(6-(2-(2-sulfonatobenzaldehyde)hydrazono)nicotinyl))-6-(nicotinoyl)hexanediamine 
 
sodium99Tcpertechnetate 
  5704-04-1   
99mTc(HYNIC-HD-NIC)(tricine) 

[1]Patent:US2005/10038,2005,A1.Locationinpatent:Page44

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Title: 99mTc-HYNIC-Gastrin Peptides: Assisted Coordination of 99mTc by Amino Acid Side Chains Results in Improved Performance Both In Vitro and In Vivo.

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Title: Clinical evaluation of antimicrobial peptide [(99m)Tc/Tricine/HYNIC(0)]ubiquicidin 29-41 as a human-specific infection imaging agent.

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Title: Post-assembly modification of Bordetella bronchiseptica O polysaccharide by a novel periplasmic enzyme encoded by wbmE.

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Title: Histoplasma capsulatum encodes a dipeptidyl peptidase active against the mammalian immunoregulatory peptide, substance P.

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Title: [Synthesis and animal imaging of 99mTc-hydrazinonicotinamide-folate as a new folate receptor-targeted tumor imaging agent].

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Title: [99mTc]HYNIC-RGD for imaging integrin alphavbeta3 expression.

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Title: In vivo tumor angiogenesis imaging with site-specific labeled (99m)Tc-HYNIC-VEGF.

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Title: Genetic screens for mutations affecting development of Xenopus tropicalis.

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Title: Asialoglycoprotein-receptor-targeted hepatocyte imaging using 99mTc galactosylated chitosan.

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Title: The decay of the ATPase activity of light plus thiol-activated thylakoid membranes in the dark.

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Title: Biochemical and morphological changes in endothelial cells in response to hypoxic interstitial edema.

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Title: HTLV-I antisense transcripts initiating in the 3'LTR are alternatively spliced and polyadenylated.

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Title: Upregulation of a tonoplast-localized cytochrome P450 during petal senescence in Petunia inflata.

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Title: Possible involvement of integrin-mediated signalling in oocyte activation: evidence that a cyclic RGD-containing peptide can stimulate protein kinase C and cortical granule exocytosis in mouse oocytes.

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Title: [The use of a new analogue DGlu-Octagastrin in scintigraphy of medullary thyroid carcinoma].

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Title: Phosphorylation of HIV-1 Tat by CDK2 in HIV-1 transcription.

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Title: Identification of a gonadotropin-releasing hormone receptor orthologue in Caenorhabditis elegans.

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Title: Human urine proteome analysis by three separation approaches.

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Title: Analysis and separation of enkephalin and dalargin analogues and fragments by capillary zone electrophoresis.

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Title: [99mTc] HYNIC-hEGF, a potential agent for imaging of EGF receptors in vivo: preparation and pre-clinical evaluation.

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Title: Structural requirements of the extracellular to transmembrane domain junction for erythropoietin receptor function.

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Title: 99mTc-labeling and in vitro and in vivo evaluation of HYNIC- and (Nalpha-His)acetic acid-modified [D-Glu1]-minigastrin.

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Title: Optimization of the preparation of 99mTc-labeled Hynic-derivatized Annexin V for human use.

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Title: Investigations into the stabilization of drugs by sugar glasses: III. The influence of various high-pH buffers.

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Title: In vitro cell studies of technetium-99m labeled RGD-HYNIC peptide, a comparison of tricine and EDDA as co-ligands.

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Title: Phosphine-containing HYNIC derivatives as potential bifunctional chelators for (99m)Tc-labeling of small biomolecules.

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Title: Comparative inhibition by substrate analogues 3-methoxy- and 3-hydroxydesaminokynurenine and an improved 3 step purification of recombinant human kynureninase.

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Title: Enhanced spontaneous activity of the mu opioid receptor by cysteine mutations: characterization of a tool for inverse agonist screening.

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Title: Effect of excipients on the stability and aerosol performance of nebulized aviscumine.

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Title: Biochemical characterization of the dissociated forms from the core antenna proteins from purple bacteria.

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Title: Optimization of expression and the purification by organic extraction of the integral membrane protein EmrE.

Journal: Protein expression and purification 20021001

Title: Analysis of lipoproteins by capillary zone electrophoresis in microfluidic devices: assay development and surface roughness measurements.

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Title: Nitriles form mixed-coligand complexes with (99m)Tc-HYNIC-peptide.

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Title: Effects of high-molecular-mass substrates on protein migration during sodium dodecyl sulfatepolyacrylamide gel electrophoresis.

Journal: Electrophoresis 20020101

Title: Effects of coligand variation on the in vivo characteristics of Tc-99m-labeled interleukin-8 in detection of infection.

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Title: Control of radioactivity pharmacokinetics of 99mTc-HYNIC-labeled polypeptides derivatized with ternary ligand complexes.

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Title: In vitro and in vivo evaluation of a Technetium-99m-labeled cyclic RGD peptide as a specific marker of alpha(V)beta(3) integrin for tumor imaging.

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Title: Expression of human beta-defensins 1 and 2 in kidneys with chronic bacterial infection.

Journal: BMC infectious diseases 20020101

Title: 99mTc-labeled divalent and tetravalent CC49 single-chain Fv's: novel imaging agents for rapid in vivo localization of human colon carcinoma.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20011001

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Title: Susceptibility to trypsinolysis of esterified milk proteins.

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Title: (99m)Tc-HYNIC-derivatized ternary ligand complexes for (99m)Tc-labeled polypeptides with low in vivo protein binding.

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Title: Conformational flexibility of tricine as a chelating agent in catena-poly-[[(tricinato)copper(II)]-mu-chloro].

Journal: Acta crystallographica. Section C, Crystal structure communications 20010101

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Tags:5704-04-1 Molecular Formula|5704-04-1 MDL|5704-04-1 SMILES|5704-04-1 Tricine