Title: Novel Hsp90 inhibitor platycodin D disrupts Hsp90/Cdc37 complex and enhances the anticancer effect of mTOR inhibitor.
Journal: Toxicology and applied pharmacology 20170901
Title: Platycodin D inhibits migration, invasion, and growth of MDA-MB-231 human breast cancer cells via suppression of EGFR-mediated Akt and MAPK pathways.
Journal: Chemico-biological interactions 20131005
Title: Saponins, especially platycodin D, from Platycodon grandiflorum modulate hepatic lipogenesis in high-fat diet-fed rats and high glucose-exposed HepG2 cells.
Journal: Toxicology and applied pharmacology 20130301
Title: Platycodin D, a triterpenoid sapoinin from Platycodon grandiflorum, ameliorates cisplatin-induced nephrotoxicity in mice.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20121201
Title: Platycodin D inhibits lipogenesis through AMPKα-PPARγ2 in 3T3-L1 cells and modulates fat accumulation in obese mice.
Journal: Planta medica 20120901
Title: Platycodin D induces reactive oxygen species-mediated apoptosis signal-regulating kinase 1 activation and endoplasmic reticulum stress response in human breast cancer cells.
Journal: Journal of medicinal food 20120801
Title: Platycodon grandiflorum modifies adipokines and the glucose uptake in high-fat diet in mice and L6 muscle cells.
Journal: The Journal of pharmacy and pharmacology 20120501
Title: [Effects of platycodin D in combination with different active ingredients of Chinese herbs on proliferation and invasion of 4T1 and MDA-MB-231 breast cancer cell lines].
Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20120101
Title: Response surface methodology to optimize enzymatic preparation of Deapio-Platycodin D and Platycodin D from Radix Platycodi.
Journal: International journal of molecular sciences 20120101
Title: Anti-atherosclerotic activity of platycodin D derived from roots of Platycodon grandiflorum in human endothelial cells.
Journal: Biological & pharmaceutical bulletin 20120101
Title: Depigmenting action of platycodin D depends on the cAMP/Rho-dependent signalling pathway.
Journal: Experimental dermatology 20111201
Title: Platycodin D and 2''-O-acetyl-polygalacin D2 isolated from Platycodon grandiflorum protect ischemia/reperfusion injury in the gerbil hippocampus.
Journal: Brain research 20090707
Title: Implication of intracellular ROS formation, caspase-3 activation and Egr-1 induction in platycodon D-induced apoptosis of U937 human leukemia cells.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20090201
Title: Anti-inflammatory activity of prosapogenin methyl ester of platycodin D via nuclear factor-kappaB pathway inhibition.
Journal: Biological & pharmaceutical bulletin 20081101
Title: Lead compounds for anti-inflammatory drugs isolated from the plants of the traditional oriental medicine in Korea.
Journal: Inflammation & allergy drug targets 20080901
Title: Cholesterol-lowering effect of platycodin D in hypercholesterolemic ICR mice.
Journal: European journal of pharmacology 20060510
Title: Platycodin D and D3 isolated from the root of Platycodon grandiflorum modulate the production of nitric oxide and secretion of TNF-alpha in activated RAW 264.7 cells.
Journal: International immunopharmacology 20040801
Title: Antinociceptive mechanisms of platycodin D administered intracerebroventricularly in the mouse.
Journal: Planta medica 20020901
Title: Platycodin D and D3 increase airway mucin release in vivo and in vitro in rats and hamsters.
Journal: Planta medica 20020301
Title: Inhibition of prostaglandin E2 production by platycodin D isolated from the root of Platycodon grandiflorum.
Journal: Planta medica 20010601
Title: Kim HL, et al. Platycodin D, a novel activator of AMP-activated protein kinase, attenuates obesity in db/db mice via regulation of adipogenesis and thermogenesis. Phytomedicine. 2019 Jan;52:254-263.
