Title: Assessment of the pharmacological properties of 5-methoxyindole derivatives at 5-HT4 receptors.
Journal: The Journal of pharmacy and pharmacology 20120801
Title: DNA cleavage induced by antitumor antibiotic leinamycin and its biological consequences.
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Title: Development and validation of an LC-MS/MS method for pharmacokinetic study of methoxyamine in phase I clinical trial.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120715
Title: Trypanosoma brucei AP endonuclease 1 has a major role in the repair of abasic sites and protection against DNA-damaging agents.
Journal: DNA repair 20120102
Title: Removal of uracil by uracil DNA glycosylase limits pemetrexed cytotoxicity: overriding the limit with methoxyamine to inhibit base excision repair.
Journal: Cell death & disease 20120101
Title: Bioactivation pathways of the cannabinoid receptor 1 antagonist rimonabant.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20111001
Title: Disproportionation of O-methylhydroxylamine catalyzed by aquapentacyanoferrate(II).
Journal: Inorganic chemistry 20110919
Title: DNA repair BER pathway inhibition increases cell death caused by oxidative DNA damage in Trypanosoma cruzi.
Journal: Journal of cellular biochemistry 20110801
Title: N-methylpurine DNA glycosylase and DNA polymerase beta modulate BER inhibitor potentiation of glioma cells to temozolomide.
Journal: Neuro-oncology 20110501
Title: Soy isoflavones augment radiation effect by inhibiting APE1/Ref-1 DNA repair activity in non-small cell lung cancer.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20110401
Title: Overcoming temozolomide resistance in glioblastoma via dual inhibition of NAD+ biosynthesis and base excision repair.
Journal: Cancer research 20110315
Title: Diphenylthiourea, a common rubber chemical, is bioactivated to potent skin sensitizers.
Journal: Chemical research in toxicology 20110114
Title: Accumulation of true single strand breaks and AP sites in base excision repair deficient cells.
Journal: Mutation research 20101210
Title: Targeting base excision repair suggests a new therapeutic strategy of fludarabine for the treatment of chronic lymphocytic leukemia.
Journal: Leukemia 20101001
Title: Role of APE1 in differentiated neuroblastoma SH-SY5Y cells in response to oxidative stress: use of APE1 small molecule inhibitors to delineate APE1 functions.
Journal: DNA repair 20091102
Title: Nucleophile addition of reduced glutathione on 2-methyl-2-nitroso compound: a combined electron paramagnetic resonance spectroscopy and electrospray tandem mass spectrometry study.
Journal: Journal of the American Society for Mass Spectrometry 20091101
Title: Direct detection and quantification of abasic sites for in vivo studies of DNA damage and repair.
Journal: Nuclear medicine and biology 20091101
Title: Inhibitory properties of trapping agents: glutathione, potassium cyanide, and methoxylamine, against major human cytochrome p450 isoforms.
Journal: Drug metabolism letters 20090401
Title: Coordination of DNA mismatch repair and base excision repair processing of chemotherapy and radiation damage for targeting resistant cancers.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090315
Title: Influence of high dietary sodium intake on the functional subtypes of alpha-adrenoceptors in the renal cortical vasculature of Wistar-Kyoto rats.
Journal: Autonomic & autacoid pharmacology 20090101
Title: The mismatch repair-mediated cell cycle checkpoint response to fluorodeoxyuridine.
Journal: Journal of cellular biochemistry 20080901
Title: [Effects of manumycin combined with methoxyamine on apoptosis in myeloid leukemia U937 cells].
Journal: Ai zheng = Aizheng = Chinese journal of cancer 20080801
Title: Carmustine-resistant cancer cells are sensitized to temozolomide as a result of enhanced mismatch repair during the development of carmustine resistance.
Journal: Molecular pharmacology 20080701
Title: Enantioselective oxidation of O-methyl-N-hydroxylamines using monoamine oxidase N as catalyst.
Journal: Chemical communications (Cambridge, England) 20070421
Title: Ape1 regulates hematopoietic differentiation of embryonic stem cells through its redox functional domain.
Journal: Blood 20070301
Title: Combined treatment with temozolomide and methoxyamine: blocking apurininc/pyrimidinic site repair coupled with targeting topoisomerase IIalpha.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070301
Title: Role for DNA polymerase beta in response to ionizing radiation.
Journal: DNA repair 20070204
Title: Manipulation of base excision repair to sensitize ovarian cancer cells to alkylating agent temozolomide.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070101
Title: The DNA base excision repair protein Ape1/Ref-1 as a therapeutic and chemopreventive target.
Journal: Molecular aspects of medicine 20070101
Title: A stronger DNA damage-induced G2 checkpoint due to over-activated CHK1 in the absence of PARP-1.
Journal: Cell cycle (Georgetown, Tex.) 20061001
Title: Base excision repair of both uracil and oxidatively damaged bases contribute to thymidine deprivation-induced radiosensitization.
Journal: International journal of radiation oncology, biology, physics 20060801
Title: Methoxyamine potentiates iododeoxyuridine-induced radiosensitization by altering cell cycle kinetics and enhancing senescence.
Journal: Molecular cancer therapeutics 20060401
Title: Improved measurement of dibenzo[a,l]pyrene-induced abasic sites by the aldehyde-reactive probe assay.
Journal: Mutation research 20051230
Title: DNA repair inhibition: a selective tumour targeting strategy.
Journal: Trends in molecular medicine 20051101
Title: Development and validation of an HPLC-UV method for the analysis of methoxyamine using 4-(diethylamino)benzaldehyde as a derivatizing agent.
Journal: Journal of pharmaceutical and biomedical analysis 20050915
Title: Simultaneous retention index analysis of urinary amino acids and carboxylic acids for graphic recognition of abnormal state.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050705
Title: Enhancement of manumycin A-induced apoptosis by methoxyamine in myeloid leukemia cells.
Journal: Leukemia 20050401
Title: Transient adenoviral N-methylpurine DNA glycosylase overexpression imparts chemotherapeutic sensitivity to human breast cancer cells.
Journal: Molecular cancer therapeutics 20040801
Title: Therapeutic impact of methoxyamine: blocking repair of abasic sites in the base excision repair pathway.
Journal: Current opinion in investigational drugs (London, England : 2000) 20040601
Title: Measurement of anti-cancer agent methoxyamine in plasma by tandem mass spectrometry with on-line sample extraction.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20031005
Title: Role of MutSalpha in the recognition of iododeoxyuridine in DNA.
Journal: Cancer research 20030901
Title: Inhibition of base excision repair potentiates iododeoxyuridine-induced cytotoxicity and radiosensitization.
Journal: Cancer research 20030215
Title: A new sensitive HPLC assay for methoxyamine and its analogs.
Journal: Journal of pharmaceutical and biomedical analysis 20021015
Title: Base excision repair as a therapeutic target in colon cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20020901
Title: Involvement of DNA polymerase beta in protection against the cytotoxicity of oxidative DNA damage.
Journal: DNA repair 20020429
Title: [Biochemical diagnosis of pheochromocytoma and neuroblastomas].
Journal: Annales de biologie clinique 20020101
Title: [Normal values of plasma methoxyamines in the setting of renal insufficiency and peri-operative stress. Consequences for the etiological diagnosis of hypertension].
Journal: Annales d'endocrinologie 20011101
Title: DNA polymerase beta mediates protection of mammalian cells against ganciclovir-induced cytotoxicity and DNA breakage.
Journal: Cancer research 20011015
Title: Beta D305A mutant of tryptophan synthase shows strongly perturbed allosteric regulation and substrate specificity.
Journal: Biochemistry 20010626
Title: Methoxyamine potentiates DNA single strand breaks and double strand breaks induced by temozolomide in colon cancer cells.
Journal: Mutation research 20010510
