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599-04-2,MFCD00005392
Catalog No.:AA0034LO

599-04-2 | D-(-)-Pantolactone

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Purity
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5g
98%
in stock  
$6.00   $4.00
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10g
98%
in stock  
$7.00   $5.00
- +
25g
98%
in stock  
$15.00   $10.00
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100g
98%
in stock  
$42.00   $29.00
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500g
98%
in stock  
$106.00   $74.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0034LO
Chemical Name:
D-(-)-Pantolactone
CAS Number:
599-04-2
Molecular Formula:
C6H10O3
Molecular Weight:
130.1418
MDL Number:
MFCD00005392
SMILES:
O[C@H]1C(=O)OCC1(C)C
Properties
Properties
 
BP:
224.6°C at 760 mmHg  
Form:
Solid  
MP:
91 °C(lit.)  
Refractive Index:
-50.8 ° (C=2, H2O)  
Stability:
Hygroscopic  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
139  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
XLogP3:
0.5  

Literature

Title: L-pantoyl lactone dehydrogenase from Rhodococcus erythropolis: genetic analyses and application to the stereospecific oxidation of L-pantoyl lactone.

Journal: Applied microbiology and biotechnology 20120701

Title: Synthesis of molluscicidal agent cyanolide a macrolactone from D-(-)-pantolactone.

Journal: The Journal of organic chemistry 20110204

Title: Biocatalytic properties of a recombinant Fusarium proliferatum lactonase with significantly enhanced production by optimal expression in Escherichia coli.

Journal: Applied biochemistry and biotechnology 20101001

Title: A striking exception to the chelate model for acyclic diastereocontrol: efficient access to a versatile propargyl alcohol for chemical synthesis.

Journal: Molecules (Basel, Switzerland) 20091215

Title: Asymmetric histidine-catalyzed cross-aldol reactions of enolizable aldehydes: access to defined configured quaternary stereogenic centers.

Journal: Journal of the American Chemical Society 20091125

Title: Synthesis and absolute configuration of novel N,O-psiconucleosides using (R)-N-phenylpantolactam as a resolution agent.

Journal: The Journal of organic chemistry 20080905

Title: Total synthesis and antitumor activity of ZK-EPO: the first fully synthetic epothilone in clinical development.

Journal: Angewandte Chemie (International ed. in English) 20061204

Title: Directed evolution and characterization of a novel D-pantonohydrolase from Fusarium moniliforme.

Journal: Journal of agricultural and food chemistry 20060809

Title: Practical resolution system for DL-pantoyl lactone using the lactonase from Fusarium oxysporum.

Journal: Journal of biotechnology 20050721

Title: Total synthesis of polycavernoside A, a lethal toxin of the red alga Polycavernosa tsudai.

Journal: The Journal of organic chemistry 20050708

Title: Exogenous supply of pantoyl lactone to excised leaves increases their pantothenate levels.

Journal: Annals of botany 20050501

Title: Gene cloning and overexpression of two conjugated polyketone reductases, novel aldo-keto reductase family enzymes, of Candida parapsilosis.

Journal: Applied microbiology and biotechnology 20040401

Title: A formal synthesis of (-)-mycalamide A.

Journal: Journal of the American Chemical Society 20040114

Title: Optical rotation of noncovalent aggregates.

Journal: Journal of the American Chemical Society 20031224

Title: Practical asymmetric synthesis of a potent Cathepsin K inhibitor. Efficient palladium removal following Suzuki coupling.

Journal: The Journal of organic chemistry 20030404

Title: (R)-2,4-Dihydroxybutyramide seco-pseudonucleosides: new versatile homochiral synthons for synthesis of modified oligonucleotides.

Journal: Organic letters 20021226

Title: Synthesis of (+/-)-5-epi-citreoviral and (+/-)-citreoviral and the kinetic resolution of an allylic silane by a [3 + 2] annulation.

Journal: Organic letters 20020822

Title: Double diastereoselective intramolecular cyclopropanation to P-chiral [3.1.0]-bicyclic phosphonates.

Journal: Organic letters 20020711

Title: A screening system for enantioselective enzymes based on differential cell growth.

Journal: Chemical communications (Cambridge, England) 20020707

Title: Synthesis of diastereomerically enriched 2-bromoesters and their reaction with nucleophiles.

Journal: Chirality 20010201

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