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611207-11-5
Catalog No.:AA00EBJ2

611207-11-5 | LH 21

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Purity
Availability
Price(USD)
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1mg
≥98%
in stock  
$86.00   $60.00
- +
5mg
≥98%
in stock  
$370.00   $259.00
- +
10mg
≥98%
in stock  
$653.00   $457.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00EBJ2
Chemical Name:
LH 21
CAS Number:
611207-11-5
Molecular Formula:
C20H20Cl3N3
Molecular Weight:
408.7519
SMILES:
CCCCCCc1nn(c(n1)c1ccc(cc1)Cl)c1ccc(cc1Cl)Cl
Properties
Computed Properties
 
Complexity:
417  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
2  
Rotatable Bond Count:
7  
XLogP3:
8  

Literature

Title: Anti-obesity efficacy of LH-21, a cannabinoid CB(1) receptor antagonist with poor brain penetration, in diet-induced obese rats.

Journal: British journal of pharmacology 20120401

Title: Central versus peripheral antagonism of cannabinoid CB1 receptor in obesity: effects of LH-21, a peripherally acting neutral cannabinoid receptor antagonist, in Zucker rats.

Journal: Journal of neuroendocrinology 20080501

Title: Pharmacological evaluation of LH-21, a newly discovered molecule that binds to cannabinoid CB1 receptor.

Journal: European journal of pharmacology 20080428

Title: Antiobesity effects of the novel in vivo neutral cannabinoid receptor antagonist 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-hexyl-1H-1,2,4-triazole--LH 21.

Journal: Neuropharmacology 20060801

Title: Discovery of 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-hexyl-1h-1,2,4-triazole, a novel in vivo cannabinoid antagonist containing a 1,2,4-triazole motif.

Journal: Journal of medicinal chemistry 20040520

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Tags:611207-11-5 Molecular Formula|611207-11-5 MDL|611207-11-5 SMILES|611207-11-5 LH 21