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620601-77-6,MFCD06796619
Catalog No.:AA00EAN2

620601-77-6 | (R)-1-Cbz-2-cyano-pyrrolidine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
97%
in stock  
$26.00   $18.00
- +
1g
97%
in stock  
$39.00   $28.00
- +
5g
97%
in stock  
$116.00   $82.00
- +
  • Technical Information
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  • Downstream Synthesis Route
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00EAN2
Chemical Name:
(R)-1-Cbz-2-cyano-pyrrolidine
CAS Number:
620601-77-6
Molecular Formula:
C13H14N2O2
Molecular Weight:
230.2625
MDL Number:
MFCD06796619
SMILES:
N#C[C@H]1CCCN1C(=O)OCc1ccccc1
Properties
Computed Properties
 
Complexity:
315  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
3  
Rotatable Bond Count:
3  
XLogP3:
1.9  

Downstream Synthesis Route
74-86-2    620601-77-6   
(+)-(R)-2-pyridin-2-yl-pyrrolidine-1-carboxylicacidbenzylester 

[1]Heller,Barbara;Sundermann,Bernd;Fischer,Christine;You,Jingsong;Chen,Waiqiang;Drexler,Hans-Joachim;Knochel,Paul;Bonrath,Werner;Gutnov,Andrey[JournalofOrganicChemistry,2003,vol.68,#24,p.9221-9225]

[1]Cobb,AlexanderJ.A.;Shaw,DavidM.;Longbottom,DeborahA.;Gold,JohanB.;Ley,StevenV.[OrganicandBiomolecularChemistry,2005,vol.3,#1,p.84-96]

[2]CurrentPatentAssignee:LIGANDPHARMACEUTICALSINC-US2009/93472,2009,A1Locationinpatent:Page/Pagecolumn29-30

[3]Merritt,J.Robert;James,Ray;Paradkar,VidyadharM.;Zhang,Chongwu;Liu,Ruiyan;Liu,Jinqi;Jacob,Biji;Chiriac,Camelia;Ohlmeyer,MichaelJ.;Quadros,Elizabeth;Wines,Pamela;Postelnek,Jennifer;Hicks,CatherineM.;Chen,Weiqing;Kimble,EarlF.;O'Brien,Linda;White,Nicole;Desai,Hema;Appell,KennethC.;Webb,MariaL.[BioorganicandMedicinalChemistryLetters,2010,vol.20,#18,p.5477-5479]

[4]Lang,JanHendrik;Jones,PeterG.;Lindel,Thomas[Chemistry-AEuropeanJournal,2017,vol.23,#52,p.12714-12717]

[1]CurrentPatentAssignee:LIGANDPHARMACEUTICALSINC-US2009/93472,2009,A1Locationinpatent:Page/Pagecolumn28

[2]Cobb,AlexanderJ.A.;Shaw,DavidM.;Longbottom,DeborahA.;Gold,JohanB.;Ley,StevenV.[OrganicandBiomolecularChemistry,2005,vol.3,#1,p.84-96]

[3]CurrentPatentAssignee:Novartis(w/oSandoz);NOVARTISAG-WO2007/9716,2007,A1Locationinpatent:Page/Pagecolumn28-29

[4]Lang,JanHendrik;Jones,PeterG.;Lindel,Thomas[Chemistry-AEuropeanJournal,2017,vol.23,#52,p.12714-12717]

[1]Cobb,AlexanderJ.A.;Shaw,DavidM.;Longbottom,DeborahA.;Gold,JohanB.;Ley,StevenV.[OrganicandBiomolecularChemistry,2005,vol.3,#1,p.84-96]

[2]Lang,JanHendrik;Jones,PeterG.;Lindel,Thomas[Chemistry-AEuropeanJournal,2017,vol.23,#52,p.12714-12717]

[1]OrganicandBiomolecularChemistry,2005,vol.3,p.84-96

[2]Chemistry-AEuropeanJournal,2017,vol.23,p.12714-12717

Literature
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